MPD: JaxKOMP-EAP genotype: Fam114a1<sup>em1(IMPC)J</sup> -/-

JaxKOMP-EAP effect sizes: Fam114a1^em1(IMPC)J -/- Gene Fam114a1

MULTIPLE (NUMERIC) TRAIT PROFILE PLOT — Early Adult Phenotyping study (EAP)

In this plot, data points are the computed genotype effect size vs. C57BL/6NJ controls, for all measured numeric phenotypes in JaxKOMP-EAP

Dimensions Width: × Height: px

Plot Options Group by Procedure Standard Error Show Effect Sizes RankZ

Significance Threshold p-Value Threshold Adjusted Unadjusted

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Procedure	JaxKOMP-EAP Trait	Trait Effect	Trait Effect SE	Trait Effect RankZ	Adjusted p-value	Unadjusted p-value

ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 6 kHz pip	-1.8114	3.1575	-0.78350	0.870	0.597
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 12 kHz pip	-0.84052	2.8158	-0.17734	0.938	0.780
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 18 kHz pip	3.1208	3.3046	0.46422	0.739	0.398
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 24 kHz pip	6.6164	4.5147	0.92954	0.609	0.217
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 30 kHz pip	2.7287	3.6925	0.40168	0.789	0.501
body composition	body length	-0.084251	0.034571	-0.75656	0.130	0.0185
body composition	body weight (at time of DXA)	0.069467	0.69089	0.16102	0.970	0.920
body composition	bone area, whole body scan, head excluded	-0.50963	0.14363	-1.6130	0.0161	0.000866
body composition	bone mineral content of whole body scan, head excluded	-0.034497	0.010222	-1.5156	0.0266	0.00145
body composition	bone mineral content to body weight ratio	-0.0014659	0.00043946	-1.5375	0.0232	0.00163
body composition	bone mineral density of whole body scan, head excluded	-0.0010695	0.00052369	-1.1024	0.222	0.0465
body composition	fat tissue mass of whole body scan, head excluded	0.48690	0.34564	0.74835	0.397	0.165
body composition	fat tissue mass to body weight ratio	0.013112	0.012185	0.63725	0.534	0.287
body composition	lean tissue mass of whole body scan, head excluded	-0.10744	0.33443	-0.38915	0.899	0.749
body composition	lean tissue mass to body weight ratio	-0.010741	0.012810	-0.64351	0.648	0.406
body composition	percent fat, whole body scan, head excluded	1.2640	1.1667	0.65745	0.532	0.284
body composition	ratio of soft-tissue attenuation coefficients	-0.0014039	0.0012973	-0.67106	0.537	0.284
body composition	tissue area	-0.054449	0.21653	-0.0041003	0.937	0.803
body composition	total tissue mass, whole body scan, head excluded	0.44816	0.22446	0.71975	0.197	0.0514
clinical blood chemistry	alanine transaminase (plasma ALT)	-0.77692	2.3830	-0.098639	0.926	0.748
clinical blood chemistry	albumin (plasma Alb)	-0.19936	0.48899	-0.24041	0.882	0.688
clinical blood chemistry	alkaline phosphatase (plasma ALP)	6.9326	3.3505	0.69464	0.201	0.0517
clinical blood chemistry	aspartate transaminase (plasma AST)	-3.6457	8.2805	-0.18104	0.878	0.665
clinical blood chemistry	aspartate transaminase to alanine transaminase ratio (plasma AST:ALT)	0.033230	0.18422	0.12380	0.959	0.859
clinical blood chemistry	blood urea nitrogen (BUN)	1.8333	1.2768	0.72251	0.409	0.166
clinical blood chemistry	calcium (plasma Ca)	0.083248	0.089802	0.92479	0.608	0.366
clinical blood chemistry	creatinine (plasma)	0.070576	0.019200	1.6972	0.0238	0.00150
clinical blood chemistry	glucose (plasma GLU, no fast)	-11.429	8.6780	-0.15415	0.398	0.203
clinical blood chemistry	HDL cholesterol (plasma HDL)	1.0621	1.8150	-0.056000	0.804	0.565
clinical blood chemistry	HDL cholesterol to total cholesterol ratio	-0.0020191	0.012894	-0.27162	0.969	0.877
clinical blood chemistry	phosphorus (plasma phosphate)	0.22251	0.31733	0.31358	0.746	0.491
clinical blood chemistry	total bilirubin (plasma TBIL)	0.036581	0.010966	1.9240	0.0570	0.00329
clinical blood chemistry	total cholesterol (plasma CHOL, no fast)	1.8004	2.2667	0.091835	0.732	0.437
clinical blood chemistry	total protein (plasma TP)	0.60867	0.95476	0.39703	0.748	0.531
clinical blood chemistry	triglyceride (plasma TG, no fast)	-11.607	8.3611	-0.42759	0.463	0.181
EKG	duration of PQ interval	0.77250	1.0714	0.97496	0.889	0.479
EKG	duration of PR interval	0.31750	1.0697	0.40799	0.940	0.770
EKG	duration of QRS interval	-0.44875	0.30913	-1.3556	0.885	0.162
EKG	duration of QT interval	-0.18500	0.95940	-0.024182	0.982	0.849
EKG	duration of QTC interval, calculated by dividing QT interval by square root of preceding RR interval	-0.24375	0.98039	-0.20906	0.986	0.806
EKG	duration of RR interval	1.2043	1.4022	0.89690	0.783	0.401
EKG	duration of ST interval	0.32500	0.94305	0.54813	0.953	0.734
EKG	heart rate coefficient of variation (signal intensity)	-0.19062	1.0792	-0.054431	0.971	0.862
EKG	heart rate variability, mean of differences between sequential beats; beats per min	-1.4550	7.8478	-0.072603	0.972	0.855
EKG	heart rate, beats per min	-10.938	11.509	-0.95197	0.738	0.353
EKG	mean R amplitude, mean amplitude of signal measured from isoelectric line to peak of QRS	0.029250	0.11916	0.13247	0.939	0.809
EKG	mean SR amplitude, mean amplitude of signal measured from signal minimum line to peak of QRS	-0.014500	0.16082	-0.15081	0.970	0.929
EKG	number of signals	6.6375	4.1377	1.2048	0.611	0.124
EKG	proportion of number pairs of successive beat-to-beat intervals that exceed 50 ms	-0.14576	2.7306	0.040703	0.991	0.958
EKG	QT dispersion, measured as inter-lead variability of QT intervals	-0.28894	2.3594	-0.052413	0.989	0.904
EKG	QTc dispersion, calculated as rate-corrected QT dispersion	0.24980	2.4422	0.064524	0.986	0.920
EKG	root mean square of successive differences of neighboring RR intervals	-0.65950	1.6718	-0.21730	0.947	0.697
glucose tolerance test	amount glucose injected	-1.3362	3.1024	-0.030942	0.890	0.672
glucose tolerance test	plasma glucose, 0min	-4.7203	9.2481	-0.68747	0.789	0.615
glucose tolerance test	plasma glucose, 15min	49.114	25.629	1.4165	0.312	0.0697
glucose tolerance test	plasma glucose, 30min	-2.8652	18.650	0.049439	0.957	0.879
glucose tolerance test	plasma glucose, 60min	-16.052	15.912	-0.55906	0.655	0.326
glucose tolerance test	plasma glucose, 120min	0.38498	10.491	-0.10314	0.983	0.971
grip strength	body weight (at time of grip strength test)	-0.72053	0.76871	-0.43073	0.548	0.358
grip strength	forelimb and hindlimb grip strength (mean of trials), average	-39.732	7.2316	-2.2705	0.000709	0.0000138
grip strength	forelimb and hindlimb grip strength (mean of trials), average normalized to bw	-1.8601	0.37708	-2.2339	0.00208	0.0000551
grip strength	forelimb and hindlimb grip strength by trial, trial1	-41.965	8.5913	-2.2339	0.00466	0.0000621
grip strength	forelimb and hindlimb grip strength by trial, trial2	-41.384	9.0842	-2.3320	0.00900	0.000141
grip strength	forelimb and hindlimb grip strength by trial, trial3	-39.306	7.8087	-2.0480	0.00288	0.0000382
grip strength	forelimb grip strength (mean of trials), average	-22.985	5.2892	-2.2339	0.00727	0.000219
grip strength	forelimb grip strength (mean of trials), average normalized to bw	-1.0616	0.26459	-1.9516	0.0143	0.000546
grip strength	forelimb grip strength by trial, trial1	-21.896	5.6804	-2.0600	0.0330	0.000760
grip strength	forelimb grip strength by trial, trial2	-25.774	6.3127	-2.2518	0.0163	0.000427
grip strength	forelimb grip strength by trial, trial3	-23.525	5.6661	-2.0364	0.0185	0.000386
heart weight	heart weight, normalized to body weight	-0.043824	0.13741	-0.63060	0.863	0.753
heart weight	heart weight, weight	-1.4688	3.8207	-0.56278	0.828	0.704
hematology	basophil differential (percent of total WBC)	0.013070	0.051743	0.23976	0.950	0.803
hematology	calculated hemoglobin (cHGB)	-0.013095	0.11753	-0.32001	0.964	0.912
hematology	eosinophil differential (percent of total WBC)	0.30952	0.22622	0.92779	0.582	0.186
hematology	hematocrit (HCT)	0.21290	0.42195	-0.14815	0.802	0.619
hematology	hemoglobin concentration distribution width (HDW)	-0.019988	0.020801	-0.56391	0.650	0.349
hematology	large unstained cells (percent of total WBC)	0.29093	0.13523	1.6459	0.284	0.0445
hematology	lymphocyte differential (percent of total WBC)	0.94150	0.87420	0.36173	0.551	0.295
hematology	mean corpuscular hemoglobin (CHr)	0.065154	0.051158	0.53857	0.447	0.217
hematology	mean platelet volume (MPV)	-0.31805	0.11396	-1.6207	0.0598	0.0113
hematology	mean RBC corpuscular hemoglobin (MCH)	0.20061	0.096155	0.75953	0.291	0.0500
hematology	mean RBC corpuscular hemoglobin concentration (MCHC)	-0.10958	0.26749	-0.25335	0.885	0.687
hematology	mean RBC corpuscular volume (MCV)	0.57232	0.29665	0.97107	0.209	0.0688
hematology	measured hemoglobin (mHGB)	0.16667	0.11836	0.17525	0.477	0.174
hematology	monocyte differential (percent of total WBC)	-0.20833	0.10962	-0.49205	0.367	0.0719
hematology	neutrophil differential (percent of total WBC)	-1.4714	0.73958	-0.67021	0.231	0.0605
hematology	platelet count (PLT; units per volume x 10³)	-42.874	32.247	-0.52943	0.572	0.199
hematology	RBC corpuscular distribution width (RDW)	-0.076942	0.10995	-0.27406	0.718	0.493
hematology	RBC corpuscular hemoglobin concentration mean (CHCM)	-0.21480	0.19696	-0.61449	0.552	0.288
hematology	red blood cell count (RBC; per volume x 10⁶)	-0.059643	0.086253	-0.59580	0.728	0.497
hematology	reticulocyte count (Retic; units per volume x 10⁹)	-11.263	11.558	-0.40127	0.717	0.341
hematology	reticulocyte differential (percent of total RBC)	-0.091905	0.11662	-0.16916	0.754	0.440
hematology	white blood cell count (WBC; units per volume x 10³)	-0.46324	0.47660	-0.14539	0.553	0.343
holeboard	number of hole pokes by individual hole number, 20 min test, 1	-0.16592	0.49240	-0.097211	0.926	0.738
holeboard	number of hole pokes by individual hole number, 20 min test, 2	0.37162	0.34764	0.71587	0.775	0.291
holeboard	number of hole pokes by individual hole number, 20 min test, 3	-0.12451	0.31847	-0.098907	0.937	0.698
holeboard	number of hole pokes by individual hole number, 20 min test, 4	0.22350	0.42431	0.30071	0.885	0.601
holeboard	number of hole pokes by individual hole number, 20 min test, 5	0.37760	0.39049	0.70934	0.790	0.339
holeboard	number of hole pokes by individual hole number, 20 min test, 6	-0.39716	0.27111	-1.1112	0.778	0.150
holeboard	number of hole pokes by individual hole number, 20 min test, 7	-0.41534	0.22074	-1.1681	0.691	0.0664
holeboard	number of hole pokes by individual hole number, 20 min test, 8	-0.50284	0.34970	-0.73563	0.701	0.157
holeboard	number of hole pokes by individual hole number, 20 min test, 9	0.21307	0.36283	0.46936	0.905	0.560
holeboard	number of hole pokes by individual hole number, 20 min test, 10	0.092045	0.23462	0.30931	0.951	0.697
holeboard	number of hole pokes by individual hole number, 20 min test, 11	-0.10170	0.22405	-0.23872	0.921	0.652
holeboard	number of hole pokes by individual hole number, 20 min test, 12	-0.18820	0.34523	-0.23666	0.898	0.588
holeboard	number of hole pokes by individual hole number, 20 min test, 13	-0.60398	0.73128	-0.51052	0.768	0.413
holeboard	number of hole pokes by individual hole number, 20 min test, 14	0.30010	0.41215	0.56510	0.839	0.470
holeboard	number of hole pokes by individual hole number, 20 min test, 15	-0.20311	0.30738	-0.23146	0.854	0.512
holeboard	number of hole pokes by individual hole number, 20 min test, 16	1.1874	0.77733	1.0333	0.559	0.134
holeboard	total number of hole pokes, 20 min test	0.097793	3.2079	0.079364	0.982	0.976
light / dark	fecal boli count, 20 min test	1.1159	0.69921	1.2093	0.512	0.118
light / dark	latency to enter dark zone, 20 min test	70.635	54.329	1.1239	0.630	0.200
light / dark	number of transitions between light and dark zones, 20 min test	0.38693	6.8082	0.15201	0.981	0.955
light / dark	percentage of total time in dark zone, 20 min test	-3.8193	4.1003	-0.56391	0.688	0.357
light / dark	percentage of total time in light zone, 20 min test	3.8193	4.1003	0.56233	0.688	0.357
light / dark	time mobile in dark zone, 20 min test	-6.2675	11.858	-0.51697	0.824	0.600
light / dark	time mobile in light zone, 20 min test	7.8052	12.944	0.27238	0.778	0.550
light / dark	time spent in dark zone, 20 min test	-52.656	60.230	-0.57026	0.749	0.387
light / dark	time spent in light zone, 20 min test	52.656	60.230	0.57026	0.749	0.387
open field	average speed in center of arena, 20 min test	-0.21532	0.37022	-0.45641	0.818	0.563
open field	average speed in periphery of arena, 20 min test	0.073469	0.15651	-0.21306	0.803	0.641
open field	distance traveled habituation ratio, 20 min test	4.2856	5.8781	0.38742	0.739	0.469
open field	distance traveled in center of arena, 20 min test	23.011	111.23	-0.25723	0.913	0.837
open field	distance traveled in periphery of arena, 20 min test	27.183	143.24	-0.31882	0.933	0.850
open field	distance traveled slope, 20 min test	2.3807	5.6917	0.29349	0.875	0.678
open field	distance traveled, 20 min test, 1st 5min	-10.013	65.574	-0.43122	0.947	0.879
open field	distance traveled, 20 min test, 2nd 5min	37.913	55.947	-0.070545	0.722	0.501
open field	distance traveled, 20 min test, 3rd 5min	8.2125	62.947	-0.33014	0.962	0.897
open field	distance traveled, 20 min test, 4th 5min	28.176	51.425	-0.12722	0.776	0.586
open field	number of clockwise revolution episodes, 20 min test	1.0125	1.2756	0.19055	0.759	0.431
open field	number of counter-clockwise revolution episodes, 20 min test	-0.13362	1.4866	-0.49398	0.968	0.929
open field	number of fecal boli, 20 min test	-0.70605	0.68518	-0.28387	0.633	0.308
open field	number of rears in 5 min bins, 20 min test, 1st 5min	1.3408	2.2823	0.16326	0.777	0.560
open field	number of rears in 5 min bins, 20 min test, 2nd 5min	3.4125	2.7884	0.53382	0.520	0.227
open field	number of rears in 5 min bins, 20 min test, 3rd 5min	2.3625	2.8938	0.25584	0.681	0.418
open field	number of rears in 5 min bins, 20 min test, 4th 5min	4.6576	2.7533	0.69102	0.329	0.0971
open field	percentage of total time in center of arena, 20 min test	2.9206	3.2016	0.44304	0.678	0.366
open field	percentage of total time in center of arena, slope, 20 min test	0.49975	1.4776	0.40484	0.944	0.737
open field	percentage of total time in center, habituation ratio, 20 min test	0.21475	1.5857	0.23371	0.973	0.893
open field	percentage of total time in corners of arena, 20 min test	-4.0094	2.9960	-0.42533	0.495	0.187
open field	percentage of total time in corners, habituation ratio, 20 min test	1.0658	1.3208	0.20072	0.849	0.424
open field	percentage of total time in corners, slope, 20 min test	0.79925	1.3647	0.093446	0.900	0.561
open field	permanence time in center of arena, 20 min test	35.045	38.419	0.44452	0.678	0.366
open field	permanence time in corners of arena, 20 min test	-48.104	35.955	-0.42533	0.495	0.187
open field	permanence time in periphery of arena, 20 min test	-35.059	38.427	-0.44452	0.678	0.366
open field	total distance traveled, 20 min test	68.915	208.38	-0.29209	0.868	0.742
open field	total number of rears, 20 min test	12.970	9.5989	0.54625	0.420	0.183
open field	whole arena average speed, 20 min test	0.058750	0.17372	-0.28090	0.866	0.737
open field	whole arena resting time, 20 min test	-9.5550	20.033	0.27392	0.783	0.635
open field	whole arena time spent mobile, 20 min test	9.4150	20.035	-0.094795	0.789	0.640
open field	whole arena time spent vertical, 20 min test	16.988	9.5975	1.2276	0.333	0.0829
SHIRPA	locomotor activity (number of squares in the arena the mouse moves into with all four paws in first 30 s of test)	-0.62191	1.2555	-0.080399	0.838	0.625
startle / PPI	average baseline movement during background noise	-0.34032	1.2459	-0.16680	0.963	0.787
startle / PPI	average of each corrected maximum percent pre-pulse inhibition value	-0.31630	0.66420	-2.2140	0.840	0.637
startle / PPI	average of each corrected percent pre-pulse inhibition value	-0.11943	0.063774	-1.2555	0.356	0.0712
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	2.0981	9.9443	0.28473	0.989	0.834
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-15.944	6.9316	-1.5902	0.290	0.0288
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-16.153	6.0511	-1.5706	0.121	0.0123
startle / PPI	average startle response to full pulse (120 dB)	32.093	39.450	0.84122	0.662	0.423
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	45.798	32.131	1.0277	0.379	0.165
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	55.067	36.633	1.1825	0.344	0.144
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	53.131	32.100	1.2717	0.295	0.109
startle / PPI	average startle response to pre-pulse, 74dB sound pressure level	-0.78604	1.2547	-0.51910	0.899	0.536
startle / PPI	average startle response to pre-pulse, 78dB sound pressure level	0.17759	1.5192	0.13562	0.985	0.908
startle / PPI	average startle response to pre-pulse, 82dB sound pressure level	-5.3644	3.0403	-2.3679	0.500	0.0878
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	0.042710	0.11006	0.44512	0.941	0.701
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-0.17066	0.072166	-1.4931	0.239	0.0249
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-0.23327	0.064942	-1.8944	0.0243	0.00120
startle / PPI	corrected average startle response to full pulse (120 dB) minus average baseline movement during background noise	32.677	39.422	0.85326	0.657	0.414
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 74dB sound pressure level	46.194	32.337	1.0183	0.375	0.164
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 78dB sound pressure level	54.832	36.382	1.1713	0.343	0.143
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 82dB sound pressure level	58.256	31.641	1.3582	0.235	0.0759
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-0.073459	0.98801	-0.63842	0.994	0.941
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-0.61107	1.1282	-2.6593	0.812	0.592
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-0.24160	0.069569	-1.8461	0.0312	0.00164
startle / PPI	corrected maximum startle response to full pulse (120 dB) minus maximum baseline movement during background noise	126.37	136.64	0.87155	0.602	0.363
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 74dB sound pressure level	195.89	108.27	1.1044	0.248	0.0808
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 78dB sound pressure level	223.33	130.43	1.2655	0.267	0.0975
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 82dB sound pressure level	221.26	113.82	1.3833	0.200	0.0617
startle / PPI	maximum baseline movement during background noise	0.064749	3.0993	0.14978	0.994	0.983
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	0.51726	10.709	0.10598	1.00	0.962
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-19.024	7.7034	-1.7288	0.239	0.0197
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-18.466	6.6911	-1.6473	0.104	0.00992
startle / PPI	maximum startle response to full pulse (120 dB)	125.77	136.35	0.86746	0.597	0.364
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	193.84	107.85	1.0992	0.250	0.0827
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	224.43	131.00	1.2655	0.268	0.0973
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	207.78	115.03	1.3171	0.242	0.0813
startle / PPI	maximum startle response to pre-pulse, 74dB sound pressure level	-2.5822	2.8379	-0.70515	0.791	0.370
startle / PPI	maximum startle response to pre-pulse, 78dB sound pressure level	0.84287	3.7984	0.26871	0.974	0.826
startle / PPI	maximum startle response to pre-pulse, 82dB sound pressure level	-14.278	7.1463	-2.5370	0.373	0.0549

MULTIPLE (CATEGORICAL) TRAIT PROFILE PLOT — Early Adult Phenotyping study (EAP)

In this plot, data points are the computed genotype effect % vs. C57BL/6NJ controls, for all measured categorical phenotypes in JaxKOMP-EAP

Dimensions Width: × Height: px

Plot Options Group by Procedure

Significance Threshold p-Value Threshold

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Procedure	JaxKOMP-EAP Trait	Trait Effect	P-value

eye morphology	anterior chamber depth	1.0 %	1.0
eye morphology	bulging eye	1.0 %	1.0
eye morphology	cornea	3.0 %	1.00
eye morphology	cornea opacity	3.0 %	1.0
eye morphology	cornea vascularization	2.0 %	1.0
eye morphology	corneal deposits	1.0 %	1.00
eye morphology	corneal mineralization	1.0 %	1.00
eye morphology	corneal scleralization	2.0 %	1.0
eye morphology	corneal ulcer	1.0 %	1.00
eye morphology	eye closure	1.0 %	1.00
eye morphology	eye hemorrhage or blood presence	1.0 %	1.0
eye morphology	eyelid morphology	1.0 %	1.00
eye morphology	eyes (present, absent)	0.0 %	1.00
eye morphology	fusion between cornea and lens	3.0 %	1.0
eye morphology	iris pigmentation	2.0 %	1.0
eye morphology	iris transillumination	1.0 %	1.00
eye morphology	irispupil	3.0 %	1.0
eye morphology	lacrimation	3.0 %	1.00
eye morphology	lens	9.0 %	1.00
eye morphology	lens opacity	7.0 %	1.00
eye morphology	narrow eye opening	1.0 %	1.00
eye morphology	optic disc	3.0 %	1.00
eye morphology	persistence of hyaloid vascular system	9.0 %	1.00
eye morphology	pupil dilation	2.0 %	1.00
eye morphology	pupil light response	2.0 %	1.0
eye morphology	pupil position	4.0 %	1.0
eye morphology	pupil shape	3.0 %	1.0
eye morphology	retina	37.0 %	0.0914
eye morphology	retinal blood vessels	3.0 %	1.00
eye morphology	retinal blood vessels pattern	25.0 %	0.0107
eye morphology	retinal blood vessels structure	3.0 %	1.0
eye morphology	retinal pigmentation	22.0 %	0.299
eye morphology	retinal structure	3.0 %	1.00
eye morphology	synechia	3.0 %	1.00
eye morphology	vitreous	3.0 %	1.0
SHIRPA	activity body position	1.0 %	1.00
SHIRPA	aggression	1.0 %	1.0
SHIRPA	body length	0.0 %	1.00
SHIRPA	body position	0.0 %	1.0
SHIRPA	body thickness	0.0 %	1.0
SHIRPA	coat color abdomen	4.0 %	1.0
SHIRPA	coat color back	0.0 %	1.00
SHIRPA	coat color head	0.0 %	1.0
SHIRPA	coat color pattern abdomen	1.0 %	1.0
SHIRPA	coat color pattern back	0.0 %	1.0
SHIRPA	coat color pattern head	0.0 %	1.00
SHIRPA	coat hair abdomen texture appearance	2.0 %	1.0
SHIRPA	coat hair back texture appearance	0.0 %	1.0
SHIRPA	coat hair distribution abdomen	1.0 %	1.00
SHIRPA	coat hair distribution back	0.0 %	1.0
SHIRPA	coat hair distribution head	1.0 %	1.0
SHIRPA	coat hair head texture appearance	0.0 %	1.0
SHIRPA	contact righting	5.0 %	1.00
SHIRPA	ear morphology	0.0 %	1.0
SHIRPA	fat distribution	0.0 %	1.00
SHIRPA	forelimb digit number	0.0 %	1.00
SHIRPA	forelimb digit position	0.0 %	1.0
SHIRPA	forelimb digit shape	0.0 %	1.0
SHIRPA	forelimb digit size	0.0 %	1.0
SHIRPA	forelimb footpads	0.0 %	1.0
SHIRPA	forelimb nail length	0.0 %	1.0
SHIRPA	forelimb nail number	0.0 %	1.0
SHIRPA	forelimb nail position	0.0 %	1.0
SHIRPA	forelimb nail shape	0.0 %	1.0
SHIRPA	forelimbs position	0.0 %	1.0
SHIRPA	forelimbs shape	0.0 %	1.0
SHIRPA	forelimbs size	0.0 %	1.0
SHIRPA	forepaw position	0.0 %	1.0
SHIRPA	forepaw shape	0.0 %	1.0
SHIRPA	forepaw size	0.0 %	1.0
SHIRPA	gait (fluidity)	0.0 %	1.00
SHIRPA	genitalia morphology	0.0 %	1.00
SHIRPA	genitalia presence	0.0 %	1.0
SHIRPA	genitalia size	0.0 %	1.0
SHIRPA	head bobbing	0.0 %	1.0
SHIRPA	head morphology	6.0 %	0.0320
SHIRPA	head size	0.0 %	1.00
SHIRPA	hindlimb digit number	0.0 %	1.00
SHIRPA	hindlimb digit position	0.0 %	1.0
SHIRPA	hindlimb digit shape	0.0 %	1.0
SHIRPA	hindlimb digit size	0.0 %	1.00
SHIRPA	hindlimb nail length	0.0 %	1.00
SHIRPA	hindlimb nail number	0.0 %	1.00
SHIRPA	hindlimb nail position	0.0 %	1.0
SHIRPA	hindlimb nail shape	0.0 %	1.0
SHIRPA	hindlimbs footpads	0.0 %	1.0
SHIRPA	hindlimbs position	0.0 %	1.0
SHIRPA	hindlimbs shape	0.0 %	1.0
SHIRPA	hindlimbs size	0.0 %	1.0
SHIRPA	hindpaw position	0.0 %	1.0
SHIRPA	hindpaw shape	0.0 %	1.0
SHIRPA	hindpaw size	0.0 %	1.0
SHIRPA	limb grasp	1.0 %	1.0
SHIRPA	lower lip morphology	0.0 %	1.0
SHIRPA	lower teeth appearance	0.0 %	1.00
SHIRPA	mouth morphology	0.0 %	1.00
SHIRPA	salivation	0.0 %	1.0
SHIRPA	skin color back paws	0.0 %	1.0
SHIRPA	skin color ear	0.0 %	1.0
SHIRPA	skin color front paws	0.0 %	1.0
SHIRPA	skin color snout	0.0 %	1.0
SHIRPA	skin color tail	0.0 %	1.0
SHIRPA	skin color whole body	0.0 %	1.0
SHIRPA	skin texture back paw	0.0 %	1.0
SHIRPA	skin texture ear	0.0 %	1.0
SHIRPA	skin texture front paws	0.0 %	1.0
SHIRPA	skin texture snout	0.0 %	1.0
SHIRPA	skin texture tail	0.0 %	1.0
SHIRPA	skin texture whole body	0.0 %	1.00
SHIRPA	snout size	0.0 %	1.0
SHIRPA	startle response	0.0 %	1.00
SHIRPA	tail curvature	0.0 %	1.0
SHIRPA	tail elevation	5.0 %	0.202
SHIRPA	tail length	0.0 %	1.00
SHIRPA	tail morphology	0.0 %	1.00
SHIRPA	tail presence	0.0 %	1.0
SHIRPA	tail shape	0.0 %	1.00
SHIRPA	tail thickness	0.0 %	1.0
SHIRPA	teeth presence	0.0 %	1.00
SHIRPA	transfer arousal	1.0 %	1.0
SHIRPA	tremor	6.0 %	0.0262
SHIRPA	trunk curl	0.0 %	1.0
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	0.0 %	1.00
SHIRPA	upper lip morphology	0.0 %	1.0
SHIRPA	upper teeth appearance	0.0 %	1.00
SHIRPA	vibrissae appearance	1.0 %	1.0
SHIRPA	vibrissae presence	2.0 %	1.0
SHIRPA	vocalization	2.0 %	1.00

GENOTYPE CORRELATION PLOT

Correlate Fam114a1^em1(IMPC)J -/- with genotype: