MPD: JaxKOMP-EAP genotype: Tex2<sup>em1(IMPC)J</sup> -/-

JaxKOMP-EAP effect sizes: Tex2^em1(IMPC)J -/- Gene Tex2

MULTIPLE (NUMERIC) TRAIT PROFILE PLOT — Early Adult Phenotyping study (EAP)

Procedure	JaxKOMP-EAP Trait	Trait Effect	Trait Effect SE	Trait Effect RankZ	Adjusted p-value	Unadjusted p-value
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 6 kHz pip	1.3980	2.3567	0.16059	0.856	0.560
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 12 kHz pip	-3.1250	2.4085	-0.68744	0.697	0.211
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 18 kHz pip	1.3125	1.8184	0.12602	0.791	0.480
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 24 kHz pip	2.0498	3.0262	0.21487	0.803	0.507
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 30 kHz pip	2.8057	2.4121	0.41540	0.642	0.260
body composition	body length	-0.18623	0.035608	-1.4913	0.000222	0.00000243
body composition	body weight (at time of DXA)	-1.2140	0.44373	-0.76878	0.0484	0.00820
body composition	bone area, whole body scan, head excluded	-0.32258	0.13977	-1.0350	0.143	0.0246
body composition	bone mineral content of whole body scan, head excluded	-0.027490	0.010427	-1.2559	0.0862	0.0107
body composition	bone mineral content to body weight ratio	-0.0012409	0.00043294	-1.2928	0.0544	0.00575
body composition	bone mineral density of whole body scan, head excluded	-0.0015932	0.00051578	-1.4817	0.0483	0.00308
body composition	fat tissue mass of whole body scan, head excluded	0.62795	0.28344	0.93100	0.159	0.0307
body composition	fat tissue mass to body weight ratio	0.026552	0.010398	1.1230	0.0829	0.0133
body composition	lean tissue mass of whole body scan, head excluded	-0.22523	0.26360	-0.63725	0.693	0.396
body composition	lean tissue mass to body weight ratio	-0.014611	0.010382	-0.83773	0.411	0.165
body composition	percent fat, whole body scan, head excluded	2.4499	1.0216	1.1359	0.112	0.0197
body composition	ratio of soft-tissue attenuation coefficients	-0.0027215	0.0011364	-1.1320	0.112	0.0199
body composition	tissue area	0.23555	0.16962	0.91354	0.452	0.170
body composition	total tissue mass, whole body scan, head excluded	0.41394	0.19161	0.66084	0.161	0.0349
clinical blood chemistry	alanine transaminase (plasma ALT)	-6.6001	5.1153	-0.60877	0.585	0.208
clinical blood chemistry	albumin (plasma Alb)	0.61606	0.41184	0.91415	0.459	0.146
clinical blood chemistry	alkaline phosphatase (plasma ALP)	6.3748	3.2243	0.61903	0.213	0.0576
clinical blood chemistry	aspartate transaminase (plasma AST)	-9.4070	16.514	-0.47048	0.824	0.573
clinical blood chemistry	aspartate transaminase to alanine transaminase ratio (plasma AST:ALT)	0.41917	0.28029	1.1635	0.524	0.146
clinical blood chemistry	blood urea nitrogen (BUN)	-1.4857	1.1595	-0.63410	0.473	0.211
clinical blood chemistry	calcium (plasma Ca)	0.14941	0.060537	1.3466	0.107	0.0197
clinical blood chemistry	creatinine (plasma)	-0.13552	0.021414	-2.0461	0.000186	7.60e-7
clinical blood chemistry	glucose (plasma GLU, no fast)	17.735	11.860	0.99633	0.328	0.146
clinical blood chemistry	HDL cholesterol (plasma HDL)	4.7488	2.0037	0.77828	0.175	0.0249
clinical blood chemistry	HDL cholesterol to total cholesterol ratio	-0.000047667	0.011341	-0.16371	0.999	0.997
clinical blood chemistry	phosphorus (plasma phosphate)	-0.20067	0.25090	-0.38632	0.702	0.430
clinical blood chemistry	total bilirubin (plasma TBIL)	-0.026010	0.0087304	-1.6576	0.0847	0.00579
clinical blood chemistry	total cholesterol (plasma CHOL, no fast)	7.7743	2.7565	1.0375	0.0903	0.00872
clinical blood chemistry	total protein (plasma TP)	-0.19148	0.56064	-0.21140	0.879	0.735
clinical blood chemistry	triglyceride (plasma TG, no fast)	-8.1954	9.2779	-0.23683	0.661	0.385
EKG	duration of PQ interval	-0.15125	0.87015	-0.014105	0.971	0.863
EKG	duration of PR interval	-0.10567	0.90638	-0.0080600	0.982	0.908
EKG	duration of QRS interval	0.15710	0.45771	0.30067	0.967	0.734
EKG	duration of QT interval	0.52250	1.0115	0.65689	0.902	0.609
EKG	duration of QTC interval, calculated by dividing QT interval by square root of preceding RR interval	-0.066250	0.88951	-0.036277	0.999	0.941
EKG	duration of RR interval	2.1813	1.9665	1.3114	0.701	0.276
EKG	duration of ST interval	0.40875	0.87687	0.62227	0.908	0.645
EKG	heart rate coefficient of variation (signal intensity)	-0.46685	0.99652	-0.30067	0.927	0.643
EKG	heart rate variability, mean of differences between sequential beats; beats per min	-3.5511	6.9884	-0.33032	0.931	0.615
EKG	heart rate, beats per min	-19.725	14.453	-1.4523	0.573	0.183
EKG	mean R amplitude, mean amplitude of signal measured from isoelectric line to peak of QRS	0.0077843	0.080421	-0.071650	0.973	0.924
EKG	mean SR amplitude, mean amplitude of signal measured from signal minimum line to peak of QRS	0.0097033	0.11134	-0.021176	0.970	0.931
EKG	number of signals	-1.4582	4.7195	-0.35597	0.948	0.760
EKG	proportion of number pairs of successive beat-to-beat intervals that exceed 50 ms	-4.2095	4.4955	-0.70808	0.846	0.357
EKG	QT dispersion, measured as inter-lead variability of QT intervals	1.4000	2.3434	0.43885	0.964	0.555
EKG	QTc dispersion, calculated as rate-corrected QT dispersion	2.3075	2.1982	0.59319	0.883	0.303
EKG	root mean square of successive differences of neighboring RR intervals	-0.87915	1.3278	-0.35597	0.899	0.513
glucose tolerance test	amount glucose injected	2.2625	2.0383	0.98253	0.652	0.277
glucose tolerance test	plasma glucose, 0min	-17.522	5.4351	-1.7022	0.0261	0.00321
glucose tolerance test	plasma glucose, 15min	-52.180	25.709	-1.3024	0.267	0.0520
glucose tolerance test	plasma glucose, 30min	-2.2547	19.587	0.068691	0.969	0.909
glucose tolerance test	plasma glucose, 60min	4.8196	15.087	0.33856	0.911	0.752
glucose tolerance test	plasma glucose, 120min	-9.8799	8.1008	-0.80350	0.543	0.233
grip strength	body weight (at time of grip strength test)	-0.44281	0.48517	-0.21340	0.560	0.368
grip strength	forelimb and hindlimb grip strength (mean of trials), average	-22.411	7.3199	-1.2969	0.0311	0.00436
grip strength	forelimb and hindlimb grip strength (mean of trials), average normalized to bw	-1.1038	0.35022	-1.3564	0.0298	0.00345
grip strength	forelimb and hindlimb grip strength by trial, trial1	-24.408	7.6466	-1.3492	0.0408	0.00310
grip strength	forelimb and hindlimb grip strength by trial, trial2	-18.276	8.5439	-0.90587	0.178	0.0399
grip strength	forelimb and hindlimb grip strength by trial, trial3	-25.226	9.1344	-1.3384	0.0764	0.00921
grip strength	forelimb grip strength (mean of trials), average	-11.381	5.1157	-1.0925	0.163	0.0331
grip strength	forelimb grip strength (mean of trials), average normalized to bw	-0.51168	0.26317	-1.0337	0.239	0.0602
grip strength	forelimb grip strength by trial, trial1	-10.629	5.3911	-0.92352	0.296	0.0571
grip strength	forelimb grip strength by trial, trial2	-15.107	6.3440	-1.3071	0.178	0.0232
grip strength	forelimb grip strength by trial, trial3	-8.0079	5.9570	-0.61636	0.497	0.188
heart weight	heart weight, normalized to body weight	0.041362	0.10251	-0.29544	0.825	0.689
heart weight	heart weight, weight	-1.4551	2.8141	-0.55331	0.764	0.608
hematology	basophil differential (percent of total WBC)	-0.092369	0.061681	-1.2261	0.586	0.145
hematology	calculated hemoglobin (cHGB)	0.33525	0.16774	0.77980	0.254	0.0548
hematology	eosinophil differential (percent of total WBC)	-0.28935	0.28579	-0.70441	0.706	0.320
hematology	hematocrit (HCT)	0.12450	0.51422	-0.24855	0.905	0.810
hematology	hemoglobin concentration distribution width (HDW)	-0.0032912	0.017357	-0.076560	0.935	0.851
hematology	large unstained cells (percent of total WBC)	-0.12835	0.084408	-0.83816	0.483	0.139
hematology	lymphocyte differential (percent of total WBC)	6.2146	3.0743	1.8652	0.228	0.0522
hematology	mean corpuscular hemoglobin (CHr)	-0.065775	0.071990	-0.52424	0.612	0.368
hematology	mean platelet volume (MPV)	-0.033741	0.10023	-0.42171	0.869	0.739
hematology	mean RBC corpuscular hemoglobin (MCH)	-0.44324	0.33609	-1.1007	0.538	0.197
hematology	mean RBC corpuscular hemoglobin concentration (MCHC)	0.21250	0.69713	0.49632	0.922	0.763
hematology	mean RBC corpuscular volume (MCV)	-1.0463	0.34424	-1.5107	0.0347	0.00498
hematology	measured hemoglobin (mHGB)	-0.10249	0.37942	-0.50240	0.904	0.789
hematology	monocyte differential (percent of total WBC)	-0.57417	0.38189	-1.2114	0.503	0.143
hematology	neutrophil differential (percent of total WBC)	-5.4623	2.9558	-1.7993	0.264	0.0745
hematology	platelet count (PLT; units per volume x 10³)	-87.621	68.863	-1.0390	0.582	0.213
hematology	RBC corpuscular distribution width (RDW)	-0.12768	0.12571	-0.44682	0.579	0.318
hematology	RBC corpuscular hemoglobin concentration mean (CHCM)	0.62047	0.22753	1.4346	0.0749	0.0107
hematology	red blood cell count (RBC; per volume x 10⁶)	0.27295	0.11025	0.84045	0.140	0.0192
hematology	reticulocyte count (Retic; units per volume x 10⁹)	10.953	11.620	0.57148	0.723	0.353
hematology	reticulocyte differential (percent of total RBC)	0.010792	0.11752	0.25644	0.976	0.927
hematology	white blood cell count (WBC; units per volume x 10³)	0.52729	0.40250	0.53415	0.404	0.200
holeboard	number of hole pokes by individual hole number, 20 min test, 1	-0.54000	0.55938	-0.46808	0.744	0.338
holeboard	number of hole pokes by individual hole number, 20 min test, 2	-0.67488	0.41098	-0.90846	0.642	0.106
holeboard	number of hole pokes by individual hole number, 20 min test, 3	-0.78919	0.34737	-1.2496	0.485	0.0268
holeboard	number of hole pokes by individual hole number, 20 min test, 4	-0.22383	0.61729	-0.11928	0.914	0.718
holeboard	number of hole pokes by individual hole number, 20 min test, 5	-0.40529	0.37817	-0.57048	0.769	0.288
holeboard	number of hole pokes by individual hole number, 20 min test, 6	-0.060096	0.23331	-0.11156	0.968	0.798
holeboard	number of hole pokes by individual hole number, 20 min test, 7	-0.32750	0.26690	-0.89737	0.803	0.225
holeboard	number of hole pokes by individual hole number, 20 min test, 8	0.0022354	0.33854	0.14483	0.999	0.995
holeboard	number of hole pokes by individual hole number, 20 min test, 9	-0.57532	0.44678	-0.90545	0.671	0.203
holeboard	number of hole pokes by individual hole number, 20 min test, 10	-0.46040	0.37852	-1.3218	0.777	0.229
holeboard	number of hole pokes by individual hole number, 20 min test, 11	-0.019903	0.29064	-0.033788	0.987	0.946
holeboard	number of hole pokes by individual hole number, 20 min test, 12	-0.51151	0.38375	-0.76070	0.625	0.188
holeboard	number of hole pokes by individual hole number, 20 min test, 13	0.20000	0.74897	0.28027	0.939	0.790
holeboard	number of hole pokes by individual hole number, 20 min test, 14	-0.030000	0.45738	0.025305	0.986	0.948
holeboard	number of hole pokes by individual hole number, 20 min test, 15	-0.33450	0.47006	-0.43876	0.852	0.480
holeboard	number of hole pokes by individual hole number, 20 min test, 16	0.30197	0.79488	0.30668	0.927	0.705
holeboard	total number of hole pokes, 20 min test	-4.3092	3.8044	-0.53566	0.559	0.262
light / dark	fecal boli count, 20 min test	-0.95095	0.62123	-1.0589	0.529	0.131
light / dark	latency to enter dark zone, 20 min test	9.6620	37.528	0.083923	0.952	0.798
light / dark	number of transitions between light and dark zones, 20 min test	9.2289	5.8702	0.95455	0.419	0.121
light / dark	percentage of total time in dark zone, 20 min test	-2.6547	3.4591	-0.34758	0.750	0.446
light / dark	percentage of total time in light zone, 20 min test	2.6547	3.4591	0.34471	0.748	0.446
light / dark	time mobile in dark zone, 20 min test	-7.6157	9.7918	-0.60562	0.721	0.440
light / dark	time mobile in light zone, 20 min test	7.3008	9.3584	0.24025	0.693	0.439
light / dark	time spent in dark zone, 20 min test	-44.566	43.053	-0.45759	0.705	0.305
light / dark	time spent in light zone, 20 min test	44.566	43.053	0.45759	0.705	0.305
open field	average speed in center of arena, 20 min test	0.37148	0.39105	0.57611	0.678	0.346
open field	average speed in periphery of arena, 20 min test	0.077077	0.14156	-0.20072	0.770	0.588
open field	distance traveled habituation ratio, 20 min test	-9.7346	6.7899	-0.81588	0.469	0.157
open field	distance traveled in center of arena, 20 min test	144.61	76.316	0.55876	0.225	0.0630
open field	distance traveled in periphery of arena, 20 min test	84.507	135.30	-0.088054	0.744	0.535
open field	distance traveled slope, 20 min test	-9.3719	6.1462	-0.82528	0.430	0.133
open field	distance traveled, 20 min test, 1st 5min	106.94	67.158	0.50768	0.319	0.117
open field	distance traveled, 20 min test, 2nd 5min	49.702	49.790	0.054402	0.570	0.322
open field	distance traveled, 20 min test, 3rd 5min	12.428	46.397	-0.27253	0.909	0.790
open field	distance traveled, 20 min test, 4th 5min	19.032	51.615	-0.24614	0.865	0.714
open field	number of clockwise revolution episodes, 20 min test	0.26269	1.2090	-0.26641	0.941	0.829
open field	number of counter-clockwise revolution episodes, 20 min test	0.41403	1.0908	-0.22406	0.855	0.706
open field	number of fecal boli, 20 min test	-3.8407	0.80999	-2.4824	0.00238	0.0000138
open field	number of rears in 5 min bins, 20 min test, 1st 5min	0.68358	1.8112	-0.030901	0.856	0.707
open field	number of rears in 5 min bins, 20 min test, 2nd 5min	0.79333	1.9040	-0.14891	0.842	0.678
open field	number of rears in 5 min bins, 20 min test, 3rd 5min	1.1408	1.9755	-0.046336	0.773	0.566
open field	number of rears in 5 min bins, 20 min test, 4th 5min	-0.95180	1.9137	-0.55562	0.812	0.621
open field	percentage of total time in center of arena, 20 min test	2.0782	2.6009	0.27810	0.728	0.427
open field	percentage of total time in center of arena, slope, 20 min test	-0.91748	1.2817	-0.38887	0.851	0.477
open field	percentage of total time in center, habituation ratio, 20 min test	-0.95149	1.2589	-0.38453	0.845	0.453
open field	percentage of total time in corners of arena, 20 min test	-0.55208	3.4042	0.21443	0.953	0.872
open field	percentage of total time in corners, habituation ratio, 20 min test	3.0498	1.6594	1.0435	0.515	0.0711
open field	percentage of total time in corners, slope, 20 min test	3.0818	1.6296	1.1007	0.499	0.0635
open field	permanence time in center of arena, 20 min test	24.929	31.209	0.27810	0.728	0.428
open field	permanence time in corners of arena, 20 min test	-6.6252	40.852	0.21443	0.953	0.872
open field	permanence time in periphery of arena, 20 min test	-24.898	31.202	-0.27671	0.728	0.428
open field	total distance traveled, 20 min test	168.17	179.04	0.026184	0.574	0.351
open field	total number of rears, 20 min test	2.0027	5.5677	-0.19798	0.861	0.720
open field	whole arena average speed, 20 min test	0.14163	0.14910	0.030213	0.569	0.346
open field	whole arena resting time, 20 min test	-8.0364	18.486	0.33156	0.804	0.665
open field	whole arena time spent mobile, 20 min test	8.1484	18.484	-0.17203	0.805	0.661
open field	whole arena time spent vertical, 20 min test	-1.9120	5.9355	-0.26279	0.904	0.748
SHIRPA	locomotor activity (number of squares in the arena the mouse moves into with all four paws in first 30 s of test)	-0.10204	1.5058	0.14418	0.987	0.946
startle / PPI	average baseline movement during background noise	-0.99505	0.99254	-0.69798	0.812	0.322
startle / PPI	average of each corrected maximum percent pre-pulse inhibition value	0.031002	0.22728	0.17107	0.955	0.892
startle / PPI	average of each corrected percent pre-pulse inhibition value	0.0044126	0.052319	-0.042795	0.968	0.933
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	6.5768	6.9452	0.76200	0.879	0.349
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-7.1465	6.4219	-0.73603	0.640	0.273
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-2.1776	5.8714	-0.33768	0.895	0.713
startle / PPI	average startle response to full pulse (120 dB)	4.2917	31.323	0.31551	0.966	0.892
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-3.7047	30.348	0.11867	0.958	0.903
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	0.81978	31.220	0.19244	0.992	0.979
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	9.0620	26.873	0.41897	0.852	0.738
startle / PPI	average startle response to pre-pulse, 74dB sound pressure level	-1.5734	1.2409	-1.0469	0.747	0.212
startle / PPI	average startle response to pre-pulse, 78dB sound pressure level	-1.4302	1.3640	-0.96333	0.814	0.301
startle / PPI	average startle response to pre-pulse, 82dB sound pressure level	4.0578	1.6110	1.3408	0.236	0.0160
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	0.067042	0.077943	0.66441	0.879	0.395
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-0.086798	0.064838	-0.79342	0.537	0.189
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	0.023223	0.066080	0.028042	0.883	0.727
startle / PPI	corrected average startle response to full pulse (120 dB) minus average baseline movement during background noise	4.9943	31.401	0.31846	0.949	0.874
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 74dB sound pressure level	-0.34751	30.388	0.16396	0.996	0.991
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 78dB sound pressure level	2.0829	31.333	0.22106	0.972	0.947
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 82dB sound pressure level	5.8083	26.796	0.34957	0.911	0.830
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	0.072800	0.69551	0.68022	0.993	0.917
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-0.085792	0.077500	-0.74483	0.622	0.275
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	0.043152	0.071306	0.14774	0.762	0.549
startle / PPI	corrected maximum startle response to full pulse (120 dB) minus maximum baseline movement during background noise	55.725	116.79	0.51910	0.828	0.636
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 74dB sound pressure level	21.707	110.02	0.28911	0.925	0.845
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 78dB sound pressure level	38.387	111.21	0.40068	0.839	0.732
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 82dB sound pressure level	19.164	99.340	0.31846	0.914	0.848
startle / PPI	maximum baseline movement during background noise	-1.7971	2.4359	-0.49837	0.847	0.465
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	7.0341	7.5881	0.73971	0.890	0.360
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-8.5321	7.2663	-0.82931	0.612	0.247
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	0.077203	6.5782	-0.16112	0.995	0.991
startle / PPI	maximum startle response to full pulse (120 dB)	53.928	116.85	0.50791	0.835	0.647
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	16.841	109.10	0.26581	0.942	0.878
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	35.029	110.78	0.37500	0.857	0.754
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	30.046	99.500	0.38555	0.871	0.764
startle / PPI	maximum startle response to pre-pulse, 74dB sound pressure level	-4.8659	3.2794	-1.3006	0.642	0.146
startle / PPI	maximum startle response to pre-pulse, 78dB sound pressure level	-3.3406	3.2753	-0.92182	0.776	0.314
startle / PPI	maximum startle response to pre-pulse, 82dB sound pressure level	13.456	3.6120	1.6809	0.0424	0.000617

MULTIPLE (CATEGORICAL) TRAIT PROFILE PLOT — Early Adult Phenotyping study (EAP)

Procedure	JaxKOMP-EAP Trait	Sex	Trait Effect	P-value
eye morphology	anterior chamber depth	females	1.0 %	1.0
eye morphology	anterior chamber depth	males	0.0 %	1.0
eye morphology	anterior chamber depth	both	1.0 %	1.0
eye morphology	bulging eye	females	1.0 %	1.0
eye morphology	bulging eye	males	0.0 %	1.0
eye morphology	bulging eye	both	1.0 %	1.00
eye morphology	cornea	females	4.0 %	1.0
eye morphology	cornea	males	2.0 %	1.0
eye morphology	cornea	both	3.0 %	1.00
eye morphology	cornea opacity	females	5.0 %	1.00
eye morphology	cornea opacity	males	1.0 %	1.0
eye morphology	cornea opacity	both	3.0 %	1.0
eye morphology	cornea vascularization	females	3.0 %	1.0
eye morphology	cornea vascularization	males	1.0 %	1.0
eye morphology	cornea vascularization	both	2.0 %	1.0
eye morphology	corneal deposits	females	2.0 %	1.0
eye morphology	corneal deposits	males	1.0 %	1.0
eye morphology	corneal deposits	both	1.0 %	1.00
eye morphology	corneal mineralization	females	2.0 %	1.0
eye morphology	corneal mineralization	males	1.0 %	1.0
eye morphology	corneal mineralization	both	1.0 %	1.00
eye morphology	corneal scleralization	females	3.0 %	1.00
eye morphology	corneal scleralization	males	1.0 %	1.0
eye morphology	corneal scleralization	both	2.0 %	1.0
eye morphology	corneal ulcer	females	1.0 %	1.0
eye morphology	corneal ulcer	males	1.0 %	1.0
eye morphology	corneal ulcer	both	1.0 %	1.00
eye morphology	eye closure	females	1.0 %	1.00
eye morphology	eye closure	males	0.0 %	1.0
eye morphology	eye closure	both	1.0 %	1.00
eye morphology	eye hemorrhage or blood presence	females	2.0 %	1.00
eye morphology	eye hemorrhage or blood presence	males	1.0 %	1.0
eye morphology	eye hemorrhage or blood presence	both	1.0 %	1.0
eye morphology	eyelid morphology	females	1.0 %	1.0
eye morphology	eyelid morphology	males	0.0 %	1.0
eye morphology	eyelid morphology	both	1.0 %	1.00
eye morphology	eyes (present, absent)	females	1.0 %	1.0
eye morphology	eyes (present, absent)	males	0.0 %	1.0
eye morphology	eyes (present, absent)	both	0.0 %	1.00
eye morphology	fusion between cornea and lens	females	4.0 %	1.00
eye morphology	fusion between cornea and lens	males	2.0 %	1.0
eye morphology	fusion between cornea and lens	both	3.0 %	1.0
eye morphology	iris pigmentation	females	2.0 %	1.0
eye morphology	iris pigmentation	males	1.0 %	1.0
eye morphology	iris pigmentation	both	2.0 %	1.0
eye morphology	iris transillumination	females	2.0 %	1.00
eye morphology	iris transillumination	males	1.0 %	1.00
eye morphology	iris transillumination	both	1.0 %	1.00
eye morphology	irispupil	females	4.0 %	1.00
eye morphology	irispupil	males	3.0 %	1.0
eye morphology	irispupil	both	3.0 %	1.0
eye morphology	lacrimation	females	3.0 %	1.0
eye morphology	lacrimation	males	2.0 %	1.00
eye morphology	lacrimation	both	3.0 %	1.00
eye morphology	lens	females	10.0 %	1.00
eye morphology	lens	males	8.0 %	1.00
eye morphology	lens	both	9.0 %	1.00
eye morphology	lens opacity	females	22.0 %	0.155
eye morphology	lens opacity	males	28.0 %	0.0279
eye morphology	lens opacity	both	21.0 %	0.0182
eye morphology	narrow eye opening	females	2.0 %	1.0
eye morphology	narrow eye opening	males	1.0 %	1.0
eye morphology	narrow eye opening	both	1.0 %	1.00
eye morphology	optic disc	females	4.0 %	1.00
eye morphology	optic disc	males	2.0 %	1.00
eye morphology	optic disc	both	3.0 %	1.00
eye morphology	persistence of hyaloid vascular system	females	14.0 %	1.0
eye morphology	persistence of hyaloid vascular system	males	15.0 %	0.262
eye morphology	persistence of hyaloid vascular system	both	3.0 %	0.745
eye morphology	pupil dilation	females	2.0 %	1.0
eye morphology	pupil dilation	males	1.0 %	1.00
eye morphology	pupil dilation	both	2.0 %	1.00
eye morphology	pupil light response	females	2.0 %	1.00
eye morphology	pupil light response	males	1.0 %	1.0
eye morphology	pupil light response	both	2.0 %	1.0
eye morphology	pupil position	females	4.0 %	1.00
eye morphology	pupil position	males	3.0 %	1.0
eye morphology	pupil position	both	4.0 %	1.0
eye morphology	pupil shape	females	3.0 %	1.00
eye morphology	pupil shape	males	2.0 %	1.0
eye morphology	pupil shape	both	3.0 %	1.0
eye morphology	retina	females	10.0 %	1.0
eye morphology	retina	males	34.0 %	0.0693
eye morphology	retina	both	9.0 %	0.307
eye morphology	retinal blood vessels	females	4.0 %	1.0
eye morphology	retinal blood vessels	males	2.0 %	1.0
eye morphology	retinal blood vessels	both	3.0 %	1.00
eye morphology	retinal blood vessels pattern	females	5.0 %	1.0
eye morphology	retinal blood vessels pattern	males	2.0 %	1.00
eye morphology	retinal blood vessels pattern	both	4.0 %	1.00
eye morphology	retinal blood vessels structure	females	4.0 %	1.00
eye morphology	retinal blood vessels structure	males	2.0 %	1.0
eye morphology	retinal blood vessels structure	both	3.0 %	1.0
eye morphology	retinal pigmentation	females	12.0 %	1.0
eye morphology	retinal pigmentation	males	53.0 %	0.00724
eye morphology	retinal pigmentation	both	16.0 %	0.177
eye morphology	retinal structure	females	4.0 %	1.00
eye morphology	retinal structure	males	2.0 %	1.00
eye morphology	retinal structure	both	3.0 %	1.00
eye morphology	synechia	females	4.0 %	1.0
eye morphology	synechia	males	2.0 %	1.00
eye morphology	synechia	both	3.0 %	1.00
eye morphology	vitreous	females	4.0 %	1.00
eye morphology	vitreous	males	2.0 %	1.0
eye morphology	vitreous	both	3.0 %	1.0
SHIRPA	activity body position	females	1.0 %	1.0
SHIRPA	activity body position	males	2.0 %	1.0
SHIRPA	activity body position	both	1.0 %	1.00
SHIRPA	aggression	females	0.0 %	1.00
SHIRPA	aggression	males	1.0 %	1.0
SHIRPA	aggression	both	1.0 %	1.0
SHIRPA	body length	females	0.0 %	1.0
SHIRPA	body length	males	0.0 %	1.00
SHIRPA	body length	both	0.0 %	1.00
SHIRPA	body position	females	0.0 %	1.0
SHIRPA	body position	males	1.0 %	1.0
SHIRPA	body position	both	0.0 %	1.0
SHIRPA	body thickness	females	1.0 %	1.0
SHIRPA	body thickness	males	0.0 %	1.0
SHIRPA	body thickness	both	0.0 %	1.0
SHIRPA	coat color abdomen	females	3.0 %	1.00
SHIRPA	coat color abdomen	males	9.0 %	0.256
SHIRPA	coat color abdomen	both	3.0 %	0.440
SHIRPA	coat color back	females	0.0 %	1.0
SHIRPA	coat color back	males	0.0 %	1.00
SHIRPA	coat color back	both	0.0 %	1.00
SHIRPA	coat color head	females	0.0 %	1.0
SHIRPA	coat color head	males	0.0 %	1.00
SHIRPA	coat color head	both	0.0 %	1.0
SHIRPA	coat color pattern abdomen	females	1.0 %	1.0
SHIRPA	coat color pattern abdomen	males	1.0 %	1.0
SHIRPA	coat color pattern abdomen	both	1.0 %	1.0
SHIRPA	coat color pattern back	females	0.0 %	1.0
SHIRPA	coat color pattern back	males	0.0 %	1.00
SHIRPA	coat color pattern back	both	0.0 %	1.0
SHIRPA	coat color pattern head	females	0.0 %	1.0
SHIRPA	coat color pattern head	males	0.0 %	1.0
SHIRPA	coat color pattern head	both	0.0 %	1.00
SHIRPA	coat hair abdomen texture appearance	females	2.0 %	1.0
SHIRPA	coat hair abdomen texture appearance	males	2.0 %	1.0
SHIRPA	coat hair abdomen texture appearance	both	2.0 %	1.0
SHIRPA	coat hair back texture appearance	females	0.0 %	1.0
SHIRPA	coat hair back texture appearance	males	0.0 %	1.0
SHIRPA	coat hair back texture appearance	both	0.0 %	1.0
SHIRPA	coat hair distribution abdomen	females	0.0 %	1.0
SHIRPA	coat hair distribution abdomen	males	1.0 %	1.00
SHIRPA	coat hair distribution abdomen	both	1.0 %	1.00
SHIRPA	coat hair distribution back	females	0.0 %	1.0
SHIRPA	coat hair distribution back	males	0.0 %	1.0
SHIRPA	coat hair distribution back	both	0.0 %	1.0
SHIRPA	coat hair distribution head	females	1.0 %	1.00
SHIRPA	coat hair distribution head	males	1.0 %	1.0
SHIRPA	coat hair distribution head	both	1.0 %	1.0
SHIRPA	coat hair head texture appearance	females	0.0 %	1.00
SHIRPA	coat hair head texture appearance	males	0.0 %	1.0
SHIRPA	coat hair head texture appearance	both	0.0 %	1.0
SHIRPA	contact righting	females	5.0 %	1.0
SHIRPA	contact righting	males	5.0 %	1.00
SHIRPA	contact righting	both	5.0 %	1.00
SHIRPA	ear morphology	females	0.0 %	1.0
SHIRPA	ear morphology	males	0.0 %	1.0
SHIRPA	ear morphology	both	0.0 %	1.0
SHIRPA	fat distribution	females	0.0 %	1.0
SHIRPA	fat distribution	males	0.0 %	1.0
SHIRPA	fat distribution	both	0.0 %	1.00
SHIRPA	forelimb digit number	females	0.0 %	1.00
SHIRPA	forelimb digit number	males	0.0 %	1.0
SHIRPA	forelimb digit number	both	0.0 %	1.00
SHIRPA	forelimb digit position	females	0.0 %	1.0
SHIRPA	forelimb digit position	males	0.0 %	1.0
SHIRPA	forelimb digit position	both	0.0 %	1.0
SHIRPA	forelimb digit shape	females	0.0 %	1.0
SHIRPA	forelimb digit shape	males	0.0 %	1.0
SHIRPA	forelimb digit shape	both	0.0 %	1.0
SHIRPA	forelimb digit size	females	0.0 %	1.0
SHIRPA	forelimb digit size	males	0.0 %	1.0
SHIRPA	forelimb digit size	both	0.0 %	1.0
SHIRPA	forelimb footpads	females	0.0 %	1.0
SHIRPA	forelimb footpads	males	0.0 %	1.0
SHIRPA	forelimb footpads	both	0.0 %	1.0
SHIRPA	forelimb nail length	females	0.0 %	1.0
SHIRPA	forelimb nail length	males	0.0 %	1.0
SHIRPA	forelimb nail length	both	0.0 %	1.0
SHIRPA	forelimb nail number	females	0.0 %	1.0
SHIRPA	forelimb nail number	males	0.0 %	1.0
SHIRPA	forelimb nail number	both	0.0 %	1.0
SHIRPA	forelimb nail position	females	0.0 %	1.0
SHIRPA	forelimb nail position	males	0.0 %	1.0
SHIRPA	forelimb nail position	both	0.0 %	1.0
SHIRPA	forelimb nail shape	females	0.0 %	1.0
SHIRPA	forelimb nail shape	males	0.0 %	1.0
SHIRPA	forelimb nail shape	both	0.0 %	1.0
SHIRPA	forelimbs position	females	0.0 %	1.0
SHIRPA	forelimbs position	males	0.0 %	1.0
SHIRPA	forelimbs position	both	0.0 %	1.0
SHIRPA	forelimbs shape	females	0.0 %	1.0
SHIRPA	forelimbs shape	males	0.0 %	1.0
SHIRPA	forelimbs shape	both	0.0 %	1.0
SHIRPA	forelimbs size	females	0.0 %	1.0
SHIRPA	forelimbs size	males	0.0 %	1.0
SHIRPA	forelimbs size	both	0.0 %	1.0
SHIRPA	forepaw position	females	0.0 %	1.0
SHIRPA	forepaw position	males	0.0 %	1.0
SHIRPA	forepaw position	both	0.0 %	1.0
SHIRPA	forepaw shape	females	0.0 %	1.0
SHIRPA	forepaw shape	males	0.0 %	1.0
SHIRPA	forepaw shape	both	0.0 %	1.0
SHIRPA	forepaw size	females	0.0 %	1.0
SHIRPA	forepaw size	males	0.0 %	1.0
SHIRPA	forepaw size	both	0.0 %	1.0
SHIRPA	gait (fluidity)	females	0.0 %	1.0
SHIRPA	gait (fluidity)	males	0.0 %	1.00
SHIRPA	gait (fluidity)	both	0.0 %	1.00
SHIRPA	genitalia morphology	females	0.0 %	1.00
SHIRPA	genitalia morphology	males	0.0 %	1.0
SHIRPA	genitalia morphology	both	0.0 %	1.00
SHIRPA	genitalia presence	females	0.0 %	1.0
SHIRPA	genitalia presence	males	0.0 %	1.0
SHIRPA	genitalia presence	both	0.0 %	1.0
SHIRPA	genitalia size	females	0.0 %	1.0
SHIRPA	genitalia size	males	0.0 %	1.0
SHIRPA	genitalia size	both	0.0 %	1.0
SHIRPA	head bobbing	females	0.0 %	1.0
SHIRPA	head bobbing	males	0.0 %	1.0
SHIRPA	head bobbing	both	0.0 %	1.0
SHIRPA	head morphology	females	0.0 %	1.0
SHIRPA	head morphology	males	0.0 %	1.00
SHIRPA	head morphology	both	0.0 %	1.0
SHIRPA	head size	females	0.0 %	1.0
SHIRPA	head size	males	0.0 %	1.0
SHIRPA	head size	both	0.0 %	1.00
SHIRPA	hindlimb digit number	females	1.0 %	1.00
SHIRPA	hindlimb digit number	males	0.0 %	1.0
SHIRPA	hindlimb digit number	both	0.0 %	1.00
SHIRPA	hindlimb digit position	females	0.0 %	1.0
SHIRPA	hindlimb digit position	males	0.0 %	1.0
SHIRPA	hindlimb digit position	both	0.0 %	1.0
SHIRPA	hindlimb digit shape	females	0.0 %	1.0
SHIRPA	hindlimb digit shape	males	0.0 %	1.0
SHIRPA	hindlimb digit shape	both	0.0 %	1.0
SHIRPA	hindlimb digit size	females	0.0 %	1.00
SHIRPA	hindlimb digit size	males	0.0 %	1.0
SHIRPA	hindlimb digit size	both	0.0 %	1.00
SHIRPA	hindlimb nail length	females	0.0 %	1.0
SHIRPA	hindlimb nail length	males	0.0 %	1.0
SHIRPA	hindlimb nail length	both	0.0 %	1.00
SHIRPA	hindlimb nail number	females	0.0 %	1.0
SHIRPA	hindlimb nail number	males	1.0 %	1.0
SHIRPA	hindlimb nail number	both	0.0 %	1.00
SHIRPA	hindlimb nail position	females	0.0 %	1.0
SHIRPA	hindlimb nail position	males	0.0 %	1.0
SHIRPA	hindlimb nail position	both	0.0 %	1.0
SHIRPA	hindlimb nail shape	females	0.0 %	1.0
SHIRPA	hindlimb nail shape	males	0.0 %	1.0
SHIRPA	hindlimb nail shape	both	0.0 %	1.0
SHIRPA	hindlimbs footpads	females	0.0 %	1.0
SHIRPA	hindlimbs footpads	males	0.0 %	1.0
SHIRPA	hindlimbs footpads	both	0.0 %	1.0
SHIRPA	hindlimbs position	females	0.0 %	1.0
SHIRPA	hindlimbs position	males	0.0 %	1.0
SHIRPA	hindlimbs position	both	0.0 %	1.0
SHIRPA	hindlimbs shape	females	0.0 %	1.0
SHIRPA	hindlimbs shape	males	0.0 %	1.0
SHIRPA	hindlimbs shape	both	0.0 %	1.0
SHIRPA	hindlimbs size	females	0.0 %	1.0
SHIRPA	hindlimbs size	males	0.0 %	1.0
SHIRPA	hindlimbs size	both	0.0 %	1.0
SHIRPA	hindpaw position	females	0.0 %	1.0
SHIRPA	hindpaw position	males	0.0 %	1.0
SHIRPA	hindpaw position	both	0.0 %	1.0
SHIRPA	hindpaw shape	females	0.0 %	1.0
SHIRPA	hindpaw shape	males	0.0 %	1.0
SHIRPA	hindpaw shape	both	0.0 %	1.0
SHIRPA	hindpaw size	females	0.0 %	1.0
SHIRPA	hindpaw size	males	0.0 %	1.0
SHIRPA	hindpaw size	both	0.0 %	1.0
SHIRPA	limb grasp	females	9.0 %	1.00
SHIRPA	limb grasp	males	6.0 %	1.0
SHIRPA	limb grasp	both	7.0 %	0.624
SHIRPA	lower lip morphology	females	0.0 %	1.0
SHIRPA	lower lip morphology	males	0.0 %	1.0
SHIRPA	lower lip morphology	both	0.0 %	1.0
SHIRPA	lower teeth appearance	females	0.0 %	1.0
SHIRPA	lower teeth appearance	males	0.0 %	1.00
SHIRPA	lower teeth appearance	both	0.0 %	1.00
SHIRPA	mouth morphology	females	0.0 %	1.0
SHIRPA	mouth morphology	males	0.0 %	1.00
SHIRPA	mouth morphology	both	0.0 %	1.00
SHIRPA	salivation	females	0.0 %	1.0
SHIRPA	salivation	males	0.0 %	1.0
SHIRPA	salivation	both	0.0 %	1.0
SHIRPA	skin color back paws	females	0.0 %	1.0
SHIRPA	skin color back paws	males	0.0 %	1.0
SHIRPA	skin color back paws	both	0.0 %	1.0
SHIRPA	skin color ear	females	0.0 %	1.0
SHIRPA	skin color ear	males	0.0 %	1.0
SHIRPA	skin color ear	both	0.0 %	1.0
SHIRPA	skin color front paws	females	0.0 %	1.0
SHIRPA	skin color front paws	males	0.0 %	1.0
SHIRPA	skin color front paws	both	0.0 %	1.0
SHIRPA	skin color snout	females	0.0 %	1.0
SHIRPA	skin color snout	males	0.0 %	1.0
SHIRPA	skin color snout	both	0.0 %	1.0
SHIRPA	skin color tail	females	0.0 %	1.0
SHIRPA	skin color tail	males	0.0 %	1.0
SHIRPA	skin color tail	both	0.0 %	1.0
SHIRPA	skin color whole body	females	0.0 %	1.0
SHIRPA	skin color whole body	males	0.0 %	1.0
SHIRPA	skin color whole body	both	0.0 %	1.0
SHIRPA	skin texture back paw	females	0.0 %	1.0
SHIRPA	skin texture back paw	males	0.0 %	1.0
SHIRPA	skin texture back paw	both	0.0 %	1.0
SHIRPA	skin texture ear	females	0.0 %	1.0
SHIRPA	skin texture ear	males	0.0 %	1.0
SHIRPA	skin texture ear	both	0.0 %	1.0
SHIRPA	skin texture front paws	females	0.0 %	1.0
SHIRPA	skin texture front paws	males	0.0 %	1.0
SHIRPA	skin texture front paws	both	0.0 %	1.0
SHIRPA	skin texture snout	females	0.0 %	1.0
SHIRPA	skin texture snout	males	0.0 %	1.0
SHIRPA	skin texture snout	both	0.0 %	1.0
SHIRPA	skin texture tail	females	0.0 %	1.0
SHIRPA	skin texture tail	males	0.0 %	1.0
SHIRPA	skin texture tail	both	0.0 %	1.0
SHIRPA	skin texture whole body	females	0.0 %	1.0
SHIRPA	skin texture whole body	males	0.0 %	1.00
SHIRPA	skin texture whole body	both	0.0 %	1.00
SHIRPA	snout size	females	0.0 %	1.0
SHIRPA	snout size	males	1.0 %	1.0
SHIRPA	snout size	both	0.0 %	1.0
SHIRPA	startle response	females	0.0 %	1.00
SHIRPA	startle response	males	0.0 %	1.00
SHIRPA	startle response	both	0.0 %	1.00
SHIRPA	tail curvature	females	0.0 %	1.00
SHIRPA	tail curvature	males	0.0 %	1.0
SHIRPA	tail curvature	both	0.0 %	1.0
SHIRPA	tail elevation	females	1.0 %	1.00
SHIRPA	tail elevation	males	2.0 %	1.0
SHIRPA	tail elevation	both	1.0 %	1.0
SHIRPA	tail length	females	0.0 %	1.0
SHIRPA	tail length	males	0.0 %	1.0
SHIRPA	tail length	both	0.0 %	1.00
SHIRPA	tail morphology	females	0.0 %	1.00
SHIRPA	tail morphology	males	0.0 %	1.0
SHIRPA	tail morphology	both	0.0 %	1.00
SHIRPA	tail presence	females	0.0 %	1.0
SHIRPA	tail presence	males	0.0 %	1.0
SHIRPA	tail presence	both	0.0 %	1.0
SHIRPA	tail shape	females	0.0 %	1.0
SHIRPA	tail shape	males	0.0 %	1.0
SHIRPA	tail shape	both	0.0 %	1.00
SHIRPA	tail thickness	females	0.0 %	1.0
SHIRPA	tail thickness	males	0.0 %	1.0
SHIRPA	tail thickness	both	0.0 %	1.0
SHIRPA	teeth presence	females	0.0 %	1.0
SHIRPA	teeth presence	males	0.0 %	1.00
SHIRPA	teeth presence	both	0.0 %	1.00
SHIRPA	transfer arousal	females	1.0 %	1.0
SHIRPA	transfer arousal	males	2.0 %	1.00
SHIRPA	transfer arousal	both	1.0 %	1.0
SHIRPA	tremor	females	0.0 %	1.0
SHIRPA	tremor	males	0.0 %	1.0
SHIRPA	tremor	both	0.0 %	1.00
SHIRPA	trunk curl	females	0.0 %	1.00
SHIRPA	trunk curl	males	0.0 %	1.0
SHIRPA	trunk curl	both	0.0 %	1.0
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	females	0.0 %	1.0
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	males	0.0 %	1.0
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	both	0.0 %	1.00
SHIRPA	upper lip morphology	females	0.0 %	1.0
SHIRPA	upper lip morphology	males	0.0 %	1.0
SHIRPA	upper lip morphology	both	0.0 %	1.0
SHIRPA	upper teeth appearance	females	0.0 %	1.0
SHIRPA	upper teeth appearance	males	0.0 %	1.0
SHIRPA	upper teeth appearance	both	0.0 %	1.00
SHIRPA	vibrissae appearance	females	2.0 %	1.0
SHIRPA	vibrissae appearance	males	1.0 %	1.0
SHIRPA	vibrissae appearance	both	1.0 %	1.0
SHIRPA	vibrissae presence	females	2.0 %	1.00
SHIRPA	vibrissae presence	males	1.0 %	1.0
SHIRPA	vibrissae presence	both	2.0 %	1.0
SHIRPA	vocalization	females	2.0 %	1.00
SHIRPA	vocalization	males	2.0 %	1.0
SHIRPA	vocalization	both	2.0 %	1.00

GENOTYPE CORRELATION PLOT

Correlate Tex2^em1(IMPC)J -/- with genotype: