MPD: JaxKOMP-EAP genotype: Rai14<sup>em1(IMPC)J</sup> -/+

JaxKOMP-EAP effect sizes: Rai14^em1(IMPC)J -/+ Gene Rai14

MULTIPLE (NUMERIC) TRAIT PROFILE PLOT — Early Adult Phenotyping study (EAP)

In this plot, data points are the computed genotype effect size vs. C57BL/6NJ controls, for all measured numeric phenotypes in JaxKOMP-EAP

Dimensions Width: × Height: px

Plot Options Group by Procedure Standard Error Show Effect Sizes RankZ

Significance Threshold p-Value Threshold Adjusted Unadjusted

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Procedure	JaxKOMP-EAP Trait	Trait Effect	Trait Effect SE	Trait Effect RankZ	Adjusted p-value	Unadjusted p-value

ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 6 kHz pip	-0.87732	1.6234	-0.53434	0.870	0.596
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 12 kHz pip	-0.063108	1.7971	-0.00070849	0.990	0.972
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 18 kHz pip	0.96698	2.0011	0.036223	0.872	0.635
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 24 kHz pip	-0.10987	3.0075	-0.13340	0.991	0.971
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 30 kHz pip	1.0377	2.3206	0.12510	0.864	0.660
body composition	body length	-0.071200	0.038953	-0.62237	0.288	0.0749
body composition	body weight (at time of DXA)	0.084175	0.51080	0.17486	0.947	0.870
body composition	bone area, whole body scan, head excluded	-0.23110	0.11692	-0.74474	0.228	0.0549
body composition	bone mineral content of whole body scan, head excluded	-0.029069	0.0081062	-1.3087	0.0196	0.000886
body composition	bone mineral content to body weight ratio	-0.0012212	0.00035911	-1.2650	0.0222	0.00151
body composition	bone mineral density of whole body scan, head excluded	-0.0019512	0.00040965	-1.7469	0.00200	0.0000240
body composition	fat tissue mass of whole body scan, head excluded	0.20724	0.29747	0.35695	0.716	0.490
body composition	fat tissue mass to body weight ratio	0.0093982	0.011225	0.48685	0.640	0.407
body composition	lean tissue mass of whole body scan, head excluded	-0.34284	0.28040	-0.88563	0.527	0.228
body composition	lean tissue mass to body weight ratio	-0.014622	0.0091221	-0.83968	0.336	0.116
body composition	percent fat, whole body scan, head excluded	1.0073	1.0646	0.54932	0.599	0.350
body composition	ratio of soft-tissue attenuation coefficients	-0.0010862	0.0011659	-0.54429	0.602	0.357
body composition	tissue area	0.029475	0.14836	0.29679	0.950	0.843
body composition	total tissue mass, whole body scan, head excluded	-0.012125	0.20013	-0.23984	0.977	0.952
clinical blood chemistry	alanine transaminase (plasma ALT)	45.182	27.633	1.8650	0.469	0.112
clinical blood chemistry	albumin (plasma Alb)	1.0003	0.41834	1.4803	0.182	0.0230
clinical blood chemistry	alkaline phosphatase (plasma ALP)	6.6380	4.1756	0.65023	0.332	0.122
clinical blood chemistry	aspartate transaminase (plasma AST)	-11.242	29.671	-0.55127	0.902	0.707
clinical blood chemistry	aspartate transaminase to alanine transaminase ratio (plasma AST:ALT)	-0.37144	0.25110	-1.1015	0.528	0.150
clinical blood chemistry	blood urea nitrogen (BUN)	-1.5505	1.3221	-0.66776	0.518	0.253
clinical blood chemistry	calcium (plasma Ca)	-0.020945	0.079959	0.20546	0.892	0.795
clinical blood chemistry	creatinine (plasma)	-0.028562	0.025907	-0.55775	0.533	0.286
clinical blood chemistry	glucose (plasma GLU, no fast)	-37.053	14.159	-0.97314	0.0660	0.0141
clinical blood chemistry	HDL cholesterol (plasma HDL)	4.1695	1.8076	0.64673	0.184	0.0282
clinical blood chemistry	HDL cholesterol to total cholesterol ratio	0.010927	0.0090792	0.44483	0.577	0.239
clinical blood chemistry	phosphorus (plasma phosphate)	-0.081241	0.26660	-0.18415	0.894	0.763
clinical blood chemistry	total bilirubin (plasma TBIL)	-0.016206	0.021341	-1.1360	0.764	0.453
clinical blood chemistry	total cholesterol (plasma CHOL, no fast)	4.3483	2.3445	0.52914	0.293	0.0746
clinical blood chemistry	total protein (plasma TP)	0.57819	0.53834	0.36938	0.570	0.292
clinical blood chemistry	triglyceride (plasma TG, no fast)	-6.3730	7.7686	-0.14067	0.690	0.420
EKG	duration of PQ interval	0.32698	0.59979	0.48594	0.924	0.589
EKG	duration of PR interval	-0.038492	0.65554	0.042327	0.992	0.953
EKG	duration of QRS interval	-0.54960	0.37577	-1.6543	0.885	0.151
EKG	duration of QT interval	-0.063492	0.86534	0.094846	0.990	0.942
EKG	duration of QTC interval, calculated by dividing QT interval by square root of preceding RR interval	0.38135	0.69897	0.47238	0.935	0.588
EKG	duration of RR interval	-1.7472	1.9615	-0.66944	0.776	0.379
EKG	duration of ST interval	0.46389	0.71014	0.71554	0.870	0.517
EKG	heart rate coefficient of variation (signal intensity)	-0.98444	0.85956	-0.72861	0.841	0.259
EKG	heart rate variability, mean of differences between sequential beats; beats per min	-6.3397	5.6255	-0.64940	0.853	0.266
EKG	heart rate, beats per min	12.765	14.666	0.52648	0.744	0.389
EKG	mean R amplitude, mean amplitude of signal measured from isoelectric line to peak of QRS	0.021429	0.074360	0.065586	0.925	0.775
EKG	mean SR amplitude, mean amplitude of signal measured from signal minimum line to peak of QRS	-0.026270	0.096497	-0.23092	0.922	0.787
EKG	number of signals	5.7659	3.4506	1.0559	0.605	0.103
EKG	proportion of number pairs of successive beat-to-beat intervals that exceed 50 ms	-4.2014	4.9698	-0.70286	0.848	0.403
EKG	QT dispersion, measured as inter-lead variability of QT intervals	2.1865	2.4270	0.68210	0.917	0.373
EKG	QTc dispersion, calculated as rate-corrected QT dispersion	2.9591	2.4256	0.78771	0.863	0.230
EKG	root mean square of successive differences of neighboring RR intervals	-0.52433	1.4968	-0.15986	0.947	0.728
grip strength	body weight (at time of grip strength test)	0.11108	0.56124	0.30341	0.915	0.844
grip strength	forelimb and hindlimb grip strength (mean of trials), average	-20.758	8.1594	-1.1638	0.0749	0.0162
grip strength	forelimb and hindlimb grip strength (mean of trials), average normalized to bw	-1.0081	0.41544	-1.2292	0.0933	0.0211
grip strength	forelimb and hindlimb grip strength by trial, trial1	-10.946	9.5105	-0.51410	0.558	0.259
grip strength	forelimb and hindlimb grip strength by trial, trial2	-33.312	11.602	-1.8460	0.0653	0.00731
grip strength	forelimb and hindlimb grip strength by trial, trial3	-20.012	11.969	-1.0437	0.328	0.104
grip strength	forelimb grip strength (mean of trials), average	-3.5980	6.4445	-0.19733	0.795	0.581
grip strength	forelimb grip strength (mean of trials), average normalized to bw	-0.13604	0.33706	-0.12522	0.858	0.689
grip strength	forelimb grip strength by trial, trial1	-4.5597	7.7778	-0.27349	0.811	0.562
grip strength	forelimb grip strength by trial, trial2	-10.756	8.1831	-0.93022	0.528	0.198
grip strength	forelimb grip strength by trial, trial3	3.6525	9.7459	0.64828	0.882	0.710
heart weight	heart weight, normalized to body weight	-0.061688	0.097655	-0.69456	0.716	0.531
heart weight	heart weight, weight	-1.7490	2.4674	-0.59312	0.680	0.482
hematology	basophil differential (percent of total WBC)	-0.17617	0.10886	-1.7973	0.543	0.116
hematology	calculated hemoglobin (cHGB)	0.15519	0.19979	0.19239	0.707	0.443
hematology	eosinophil differential (percent of total WBC)	0.045419	0.30434	0.20170	0.967	0.882
hematology	hematocrit (HCT)	0.82921	0.78155	0.58045	0.588	0.297
hematology	hemoglobin concentration distribution width (HDW)	-0.029758	0.021730	-0.82538	0.483	0.181
hematology	large unstained cells (percent of total WBC)	-0.040694	0.12197	-0.26808	0.890	0.741
hematology	lymphocyte differential (percent of total WBC)	2.8007	1.7881	0.94939	0.367	0.128
hematology	mean corpuscular hemoglobin (CHr)	-0.020779	0.041121	-0.15477	0.807	0.617
hematology	mean platelet volume (MPV)	-0.22071	0.14083	-1.3092	0.309	0.128
hematology	mean RBC corpuscular hemoglobin (MCH)	-1.4065	0.78212	-1.8152	0.378	0.0822
hematology	mean RBC corpuscular hemoglobin concentration (MCHC)	-3.0656	1.7017	-1.9863	0.381	0.0817
hematology	mean RBC corpuscular volume (MCV)	0.73521	0.40111	1.2316	0.222	0.0771
hematology	measured hemoglobin (mHGB)	-1.1610	0.76673	-1.7527	0.424	0.140
hematology	monocyte differential (percent of total WBC)	-0.13993	0.38347	-0.26834	0.898	0.718
hematology	neutrophil differential (percent of total WBC)	-2.2034	1.6657	-0.91978	0.445	0.196
hematology	platelet count (PLT; units per volume x 10³)	31.655	58.270	0.49051	0.840	0.591
hematology	RBC corpuscular distribution width (RDW)	0.010390	0.098176	0.025357	0.964	0.916
hematology	RBC corpuscular hemoglobin concentration mean (CHCM)	-0.63930	0.28845	-1.5513	0.157	0.0347
hematology	red blood cell count (RBC; per volume x 10⁶)	0.12831	0.14706	0.24742	0.651	0.390
hematology	reticulocyte count (Retic; units per volume x 10⁹)	1.0760	13.767	0.14958	0.991	0.938
hematology	reticulocyte differential (percent of total RBC)	-0.17779	0.14065	-0.55819	0.586	0.216
hematology	white blood cell count (WBC; units per volume x 10³)	0.093256	0.61078	0.25278	0.932	0.880
holeboard	number of hole pokes by individual hole number, 20 min test, 1	-0.49731	0.72114	-0.41964	0.829	0.494
holeboard	number of hole pokes by individual hole number, 20 min test, 2	-1.3891	0.47238	-1.8863	0.290	0.00531
holeboard	number of hole pokes by individual hole number, 20 min test, 3	-0.13314	0.39081	-0.12609	0.941	0.735
holeboard	number of hole pokes by individual hole number, 20 min test, 4	-1.5835	0.66146	-1.5386	0.337	0.0213
holeboard	number of hole pokes by individual hole number, 20 min test, 5	0.40273	0.33070	0.74674	0.725	0.230
holeboard	number of hole pokes by individual hole number, 20 min test, 6	0.26236	0.25144	0.73836	0.855	0.303
holeboard	number of hole pokes by individual hole number, 20 min test, 7	-0.38709	0.36281	-1.0852	0.837	0.292
holeboard	number of hole pokes by individual hole number, 20 min test, 8	-0.44782	0.42942	-0.64771	0.790	0.303
holeboard	number of hole pokes by individual hole number, 20 min test, 9	-0.10964	0.35918	-0.10492	0.958	0.762
holeboard	number of hole pokes by individual hole number, 20 min test, 10	-0.036711	0.34088	-0.016915	0.983	0.915
holeboard	number of hole pokes by individual hole number, 20 min test, 11	0.11111	0.30833	0.31953	0.943	0.720
holeboard	number of hole pokes by individual hole number, 20 min test, 12	-0.35138	0.47902	-0.51052	0.840	0.467
holeboard	number of hole pokes by individual hole number, 20 min test, 13	-0.44347	0.89224	-0.36559	0.883	0.622
holeboard	number of hole pokes by individual hole number, 20 min test, 14	-0.24576	0.50691	-0.29433	0.879	0.630
holeboard	number of hole pokes by individual hole number, 20 min test, 15	0.17912	0.50273	0.33153	0.913	0.723
holeboard	number of hole pokes by individual hole number, 20 min test, 16	-1.5732	0.88833	-1.3823	0.501	0.0840
holeboard	total number of hole pokes, 20 min test	-6.1998	3.5721	-0.78342	0.327	0.0900
light / dark	fecal boli count, 20 min test	-0.94714	0.80631	-1.0483	0.648	0.247
light / dark	latency to enter dark zone, 20 min test	-124.10	40.901	-2.2978	0.130	0.00413
light / dark	number of transitions between light and dark zones, 20 min test	8.3818	5.3613	0.86851	0.427	0.125
light / dark	percentage of total time in dark zone, 20 min test	-6.6222	3.8142	-1.0413	0.426	0.0900
light / dark	percentage of total time in light zone, 20 min test	6.6222	3.8142	1.0367	0.426	0.0900
light / dark	time mobile in dark zone, 20 min test	4.4259	11.110	0.20836	0.871	0.692
light / dark	time mobile in light zone, 20 min test	18.103	11.470	0.77380	0.345	0.122
light / dark	time spent in dark zone, 20 min test	5.7735	52.207	0.29631	0.971	0.912
light / dark	time spent in light zone, 20 min test	-5.7735	52.207	-0.29631	0.971	0.912
open field	average speed in center of arena, 20 min test	-0.10656	0.34136	-0.29489	0.914	0.756
open field	average speed in periphery of arena, 20 min test	0.15603	0.14770	0.10964	0.525	0.297
open field	distance traveled habituation ratio, 20 min test	-3.6813	7.6080	-0.26974	0.841	0.631
open field	distance traveled in center of arena, 20 min test	90.521	83.653	0.23785	0.539	0.285
open field	distance traveled in periphery of arena, 20 min test	122.74	143.69	0.073237	0.644	0.398
open field	distance traveled slope, 20 min test	-6.4087	7.2444	-0.55249	0.688	0.381
open field	distance traveled, 20 min test, 1st 5min	74.717	66.502	0.25168	0.512	0.267
open field	distance traveled, 20 min test, 2nd 5min	91.049	55.979	0.52455	0.306	0.111
open field	distance traveled, 20 min test, 3rd 5min	2.2242	56.748	-0.39902	0.992	0.969
open field	distance traveled, 20 min test, 4th 5min	27.889	58.208	-0.13128	0.808	0.634
open field	number of clockwise revolution episodes, 20 min test	-0.67361	1.6037	-0.82489	0.882	0.677
open field	number of counter-clockwise revolution episodes, 20 min test	0.61969	0.85913	-0.11234	0.722	0.475
open field	number of fecal boli, 20 min test	0.30217	0.95209	0.48216	0.890	0.752
open field	number of rears in 5 min bins, 20 min test, 1st 5min	2.7856	2.1006	0.55517	0.451	0.192
open field	number of rears in 5 min bins, 20 min test, 2nd 5min	5.9400	2.1263	1.1513	0.0768	0.00782
open field	number of rears in 5 min bins, 20 min test, 3rd 5min	6.5189	2.1703	1.1592	0.0543	0.00448
open field	number of rears in 5 min bins, 20 min test, 4th 5min	7.3850	2.8752	1.2596	0.121	0.0138
open field	percentage of total time in center of arena, 20 min test	3.2627	2.7543	0.53227	0.561	0.243
open field	percentage of total time in center of arena, slope, 20 min test	0.88640	1.3572	0.61945	0.867	0.517
open field	percentage of total time in center, habituation ratio, 20 min test	1.2833	1.3603	0.81588	0.799	0.351
open field	percentage of total time in corners of arena, 20 min test	-5.5323	3.5704	-0.73253	0.431	0.129
open field	percentage of total time in corners, habituation ratio, 20 min test	0.82772	2.2756	0.10019	0.947	0.718
open field	percentage of total time in corners, slope, 20 min test	1.0397	2.2928	0.20346	0.926	0.653
open field	permanence time in center of arena, 20 min test	39.157	33.052	0.53537	0.561	0.243
open field	permanence time in corners of arena, 20 min test	-66.392	42.844	-0.73253	0.431	0.129
open field	permanence time in periphery of arena, 20 min test	-39.219	33.051	-0.53537	0.559	0.242
open field	total distance traveled, 20 min test	196.69	199.51	0.093446	0.553	0.330
open field	total number of rears, 20 min test	23.089	7.7571	1.2106	0.0474	0.00482
open field	whole arena average speed, 20 min test	0.16369	0.16633	0.094795	0.555	0.331
open field	whole arena resting time, 20 min test	-21.886	18.997	-0.079970	0.456	0.256
open field	whole arena time spent mobile, 20 min test	21.966	19.000	0.33156	0.458	0.254
open field	whole arena time spent vertical, 20 min test	18.513	7.9938	1.3278	0.184	0.0255
SHIRPA	locomotor activity (number of squares in the arena the mouse moves into with all four paws in first 30 s of test)	1.0733	1.1764	0.63298	0.667	0.368
startle / PPI	average baseline movement during background noise	-1.4818	0.82033	-0.98586	0.579	0.0780
startle / PPI	average of each corrected maximum percent pre-pulse inhibition value	-0.13975	0.065392	-1.3512	0.276	0.0385
startle / PPI	average of each corrected percent pre-pulse inhibition value	-0.11052	0.058978	-1.1623	0.351	0.0679
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-15.541	6.1595	-1.5658	0.641	0.0156
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-12.340	6.3690	-1.2655	0.363	0.0594
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-2.2945	6.5903	-0.35852	0.901	0.729
startle / PPI	average startle response to full pulse (120 dB)	-22.632	28.174	-0.26001	0.663	0.426
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-5.9928	30.122	0.076436	0.930	0.843
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-5.2274	25.049	0.075031	0.906	0.836
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-19.782	24.210	-0.29496	0.622	0.418
startle / PPI	average startle response to pre-pulse, 74dB sound pressure level	-1.6335	1.5476	-1.1122	0.785	0.297
startle / PPI	average startle response to pre-pulse, 78dB sound pressure level	-0.73283	1.3242	-0.49045	0.913	0.583
startle / PPI	average startle response to pre-pulse, 82dB sound pressure level	-1.7512	1.5803	-1.0890	0.697	0.274
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-0.18553	0.074249	-1.5424	0.657	0.0165
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-0.11371	0.069975	-1.0342	0.428	0.112
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-0.017963	0.075405	-0.32528	0.922	0.813
startle / PPI	corrected average startle response to full pulse (120 dB) minus average baseline movement during background noise	-21.747	28.454	-0.24554	0.687	0.449
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 74dB sound pressure level	-4.3594	30.677	0.098941	0.951	0.888
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 78dB sound pressure level	-4.4945	25.188	0.086277	0.921	0.859
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 82dB sound pressure level	-18.031	24.172	-0.23833	0.658	0.460
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-0.20860	0.076142	-1.5755	0.434	0.00899
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-0.15720	0.081112	-1.3003	0.320	0.0594
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-0.040644	0.082591	-0.47893	0.818	0.625
startle / PPI	corrected maximum startle response to full pulse (120 dB) minus maximum baseline movement during background noise	-99.310	102.28	-0.34213	0.580	0.337
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 74dB sound pressure level	-5.7969	106.61	0.14695	0.979	0.957
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 78dB sound pressure level	9.2439	92.757	0.22537	0.952	0.921
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 82dB sound pressure level	-56.990	89.365	-0.16254	0.710	0.527
startle / PPI	maximum baseline movement during background noise	-3.5925	1.9537	-0.97905	0.539	0.0730
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-18.165	6.6875	-1.6365	0.550	0.00962
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-16.091	7.6176	-1.4809	0.309	0.0406
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-4.7344	7.5927	-0.56618	0.788	0.536
startle / PPI	maximum startle response to full pulse (120 dB)	-101.62	102.00	-0.35255	0.569	0.325
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-10.609	105.27	0.12997	0.957	0.920
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	7.0037	92.424	0.20387	0.966	0.940
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-59.580	89.667	-0.18958	0.694	0.510
startle / PPI	maximum startle response to pre-pulse, 74dB sound pressure level	-4.8121	4.2521	-1.2844	0.738	0.264
startle / PPI	maximum startle response to pre-pulse, 78dB sound pressure level	-2.4396	3.4728	-0.68552	0.850	0.486
startle / PPI	maximum startle response to pre-pulse, 82dB sound pressure level	-2.5897	3.8588	-0.70695	0.822	0.506

MULTIPLE (CATEGORICAL) TRAIT PROFILE PLOT — Early Adult Phenotyping study (EAP)

In this plot, data points are the computed genotype effect % vs. C57BL/6NJ controls, for all measured categorical phenotypes in JaxKOMP-EAP

Dimensions Width: × Height: px

Plot Options Group by Procedure

Include Sexes Data Both Females Males

Significance Threshold p-Value Threshold

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Procedure	JaxKOMP-EAP Trait	Sex	Trait Effect	P-value

eye morphology	anterior chamber depth	females	1.0 %	1.0
eye morphology	anterior chamber depth	males	0.0 %	1.0
eye morphology	anterior chamber depth	both	1.0 %	1.0
eye morphology	bulging eye	females	1.0 %	1.0
eye morphology	bulging eye	males	0.0 %	1.0
eye morphology	bulging eye	both	1.0 %	1.00
eye morphology	cornea	females	4.0 %	1.0
eye morphology	cornea	males	2.0 %	1.0
eye morphology	cornea	both	3.0 %	1.0
eye morphology	cornea opacity	females	5.0 %	1.0
eye morphology	cornea opacity	males	1.0 %	1.0
eye morphology	cornea opacity	both	3.0 %	1.0
eye morphology	cornea vascularization	females	3.0 %	1.0
eye morphology	cornea vascularization	males	1.0 %	1.0
eye morphology	cornea vascularization	both	2.0 %	1.0
eye morphology	corneal deposits	females	2.0 %	1.0
eye morphology	corneal deposits	males	1.0 %	1.0
eye morphology	corneal deposits	both	1.0 %	1.0
eye morphology	corneal mineralization	females	2.0 %	1.0
eye morphology	corneal mineralization	males	1.0 %	1.0
eye morphology	corneal mineralization	both	1.0 %	1.00
eye morphology	corneal scleralization	females	3.0 %	1.0
eye morphology	corneal scleralization	males	1.0 %	1.0
eye morphology	corneal scleralization	both	2.0 %	1.0
eye morphology	corneal ulcer	females	1.0 %	1.0
eye morphology	corneal ulcer	males	1.0 %	1.0
eye morphology	corneal ulcer	both	1.0 %	1.00
eye morphology	eye closure	females	1.0 %	1.0
eye morphology	eye closure	males	0.0 %	1.0
eye morphology	eye closure	both	1.0 %	1.0
eye morphology	eye hemorrhage or blood presence	females	2.0 %	1.0
eye morphology	eye hemorrhage or blood presence	males	1.0 %	1.0
eye morphology	eye hemorrhage or blood presence	both	1.0 %	1.0
eye morphology	eyelid morphology	females	1.0 %	1.0
eye morphology	eyelid morphology	males	0.0 %	1.0
eye morphology	eyelid morphology	both	1.0 %	1.0
eye morphology	eyes (present, absent)	females	1.0 %	1.0
eye morphology	eyes (present, absent)	males	0.0 %	1.0
eye morphology	eyes (present, absent)	both	0.0 %	1.0
eye morphology	fusion between cornea and lens	females	4.0 %	1.0
eye morphology	fusion between cornea and lens	males	2.0 %	1.0
eye morphology	fusion between cornea and lens	both	3.0 %	1.0
eye morphology	iris pigmentation	females	2.0 %	1.0
eye morphology	iris pigmentation	males	1.0 %	1.0
eye morphology	iris pigmentation	both	2.0 %	1.0
eye morphology	iris transillumination	females	2.0 %	1.0
eye morphology	iris transillumination	males	1.0 %	1.00
eye morphology	iris transillumination	both	1.0 %	1.00
eye morphology	irispupil	females	4.0 %	1.0
eye morphology	irispupil	males	3.0 %	1.0
eye morphology	irispupil	both	3.0 %	1.0
eye morphology	lacrimation	females	3.0 %	1.0
eye morphology	lacrimation	males	2.0 %	1.0
eye morphology	lacrimation	both	3.0 %	1.0
eye morphology	lens	females	10.0 %	1.0
eye morphology	lens	males	8.0 %	1.00
eye morphology	lens	both	9.0 %	1.0
eye morphology	lens opacity	females	8.0 %	0.573
eye morphology	lens opacity	males	17.0 %	0.0282
eye morphology	lens opacity	both	9.0 %	0.0784
eye morphology	narrow eye opening	females	2.0 %	1.00
eye morphology	narrow eye opening	males	1.0 %	1.0
eye morphology	narrow eye opening	both	1.0 %	1.00
eye morphology	optic disc	females	4.0 %	1.0
eye morphology	optic disc	males	2.0 %	1.0
eye morphology	optic disc	both	3.0 %	1.00
eye morphology	persistence of hyaloid vascular system	females	20.0 %	0.190
eye morphology	persistence of hyaloid vascular system	males	5.0 %	1.0
eye morphology	persistence of hyaloid vascular system	both	7.0 %	0.311
eye morphology	pupil dilation	females	2.0 %	1.0
eye morphology	pupil dilation	males	1.0 %	1.0
eye morphology	pupil dilation	both	2.0 %	1.0
eye morphology	pupil light response	females	2.0 %	1.0
eye morphology	pupil light response	males	1.0 %	1.0
eye morphology	pupil light response	both	2.0 %	1.0
eye morphology	pupil position	females	4.0 %	1.0
eye morphology	pupil position	males	3.0 %	1.0
eye morphology	pupil position	both	4.0 %	1.0
eye morphology	pupil shape	females	3.0 %	1.0
eye morphology	pupil shape	males	2.0 %	1.0
eye morphology	pupil shape	both	3.0 %	1.0
eye morphology	retina	females	8.0 %	0.603
eye morphology	retina	males	17.0 %	0.180
eye morphology	retina	both	9.0 %	0.295
eye morphology	retinal blood vessels	females	4.0 %	1.0
eye morphology	retinal blood vessels	males	2.0 %	1.0
eye morphology	retinal blood vessels	both	3.0 %	1.0
eye morphology	retinal blood vessels pattern	females	5.0 %	1.0
eye morphology	retinal blood vessels pattern	males	2.0 %	1.00
eye morphology	retinal blood vessels pattern	both	4.0 %	1.0
eye morphology	retinal blood vessels structure	females	4.0 %	1.0
eye morphology	retinal blood vessels structure	males	2.0 %	1.0
eye morphology	retinal blood vessels structure	both	3.0 %	1.0
eye morphology	retinal pigmentation	females	12.0 %	1.0
eye morphology	retinal pigmentation	males	14.0 %	1.0
eye morphology	retinal pigmentation	both	13.0 %	1.0
eye morphology	retinal structure	females	4.0 %	1.0
eye morphology	retinal structure	males	2.0 %	1.00
eye morphology	retinal structure	both	3.0 %	1.00
eye morphology	synechia	females	4.0 %	1.0
eye morphology	synechia	males	2.0 %	1.0
eye morphology	synechia	both	3.0 %	1.00
eye morphology	vitreous	females	4.0 %	1.0
eye morphology	vitreous	males	2.0 %	1.0
eye morphology	vitreous	both	3.0 %	1.0
SHIRPA	activity body position	females	1.0 %	1.0
SHIRPA	activity body position	males	2.0 %	1.0
SHIRPA	activity body position	both	1.0 %	1.00
SHIRPA	aggression	females	0.0 %	1.00
SHIRPA	aggression	males	1.0 %	1.0
SHIRPA	aggression	both	1.0 %	1.0
SHIRPA	body length	females	0.0 %	1.00
SHIRPA	body length	males	0.0 %	1.00
SHIRPA	body length	both	0.0 %	1.00
SHIRPA	body position	females	0.0 %	1.00
SHIRPA	body position	males	1.0 %	1.0
SHIRPA	body position	both	0.0 %	1.0
SHIRPA	body thickness	females	1.0 %	1.0
SHIRPA	body thickness	males	0.0 %	1.0
SHIRPA	body thickness	both	0.0 %	1.0
SHIRPA	coat color abdomen	females	3.0 %	1.00
SHIRPA	coat color abdomen	males	4.0 %	1.0
SHIRPA	coat color abdomen	both	4.0 %	1.0
SHIRPA	coat color back	females	0.0 %	1.00
SHIRPA	coat color back	males	0.0 %	1.0
SHIRPA	coat color back	both	0.0 %	1.00
SHIRPA	coat color head	females	0.0 %	1.00
SHIRPA	coat color head	males	0.0 %	1.0
SHIRPA	coat color head	both	0.0 %	1.0
SHIRPA	coat color pattern abdomen	females	1.0 %	1.00
SHIRPA	coat color pattern abdomen	males	1.0 %	1.00
SHIRPA	coat color pattern abdomen	both	1.0 %	1.00
SHIRPA	coat color pattern back	females	0.0 %	1.00
SHIRPA	coat color pattern back	males	0.0 %	1.0
SHIRPA	coat color pattern back	both	0.0 %	1.0
SHIRPA	coat color pattern head	females	0.0 %	1.00
SHIRPA	coat color pattern head	males	0.0 %	1.00
SHIRPA	coat color pattern head	both	0.0 %	1.00
SHIRPA	coat hair abdomen texture appearance	females	2.0 %	1.0
SHIRPA	coat hair abdomen texture appearance	males	2.0 %	1.0
SHIRPA	coat hair abdomen texture appearance	both	2.0 %	1.0
SHIRPA	coat hair back texture appearance	females	0.0 %	1.0
SHIRPA	coat hair back texture appearance	males	0.0 %	1.0
SHIRPA	coat hair back texture appearance	both	0.0 %	1.0
SHIRPA	coat hair distribution abdomen	females	0.0 %	1.00
SHIRPA	coat hair distribution abdomen	males	1.0 %	1.0
SHIRPA	coat hair distribution abdomen	both	1.0 %	1.0
SHIRPA	coat hair distribution back	females	0.0 %	1.00
SHIRPA	coat hair distribution back	males	0.0 %	1.00
SHIRPA	coat hair distribution back	both	0.0 %	1.0
SHIRPA	coat hair distribution head	females	1.0 %	1.00
SHIRPA	coat hair distribution head	males	1.0 %	1.0
SHIRPA	coat hair distribution head	both	1.0 %	1.0
SHIRPA	coat hair head texture appearance	females	0.0 %	1.00
SHIRPA	coat hair head texture appearance	males	0.0 %	1.0
SHIRPA	coat hair head texture appearance	both	0.0 %	1.0
SHIRPA	contact righting	females	5.0 %	1.0
SHIRPA	contact righting	males	5.0 %	1.0
SHIRPA	contact righting	both	5.0 %	0.624
SHIRPA	ear morphology	females	0.0 %	1.0
SHIRPA	ear morphology	males	0.0 %	1.0
SHIRPA	ear morphology	both	0.0 %	1.0
SHIRPA	fat distribution	females	0.0 %	1.00
SHIRPA	fat distribution	males	0.0 %	1.0
SHIRPA	fat distribution	both	0.0 %	1.00
SHIRPA	forelimb digit number	females	0.0 %	1.00
SHIRPA	forelimb digit number	males	0.0 %	1.0
SHIRPA	forelimb digit number	both	0.0 %	1.00
SHIRPA	forelimb digit position	females	0.0 %	1.0
SHIRPA	forelimb digit position	males	0.0 %	1.0
SHIRPA	forelimb digit position	both	0.0 %	1.0
SHIRPA	forelimb digit shape	females	0.0 %	1.0
SHIRPA	forelimb digit shape	males	0.0 %	1.0
SHIRPA	forelimb digit shape	both	0.0 %	1.0
SHIRPA	forelimb digit size	females	0.0 %	1.0
SHIRPA	forelimb digit size	males	0.0 %	1.0
SHIRPA	forelimb digit size	both	0.0 %	1.0
SHIRPA	forelimb footpads	females	0.0 %	1.00
SHIRPA	forelimb footpads	males	0.0 %	1.0
SHIRPA	forelimb footpads	both	0.0 %	1.0
SHIRPA	forelimb nail length	females	0.0 %	1.0
SHIRPA	forelimb nail length	males	0.0 %	1.0
SHIRPA	forelimb nail length	both	0.0 %	1.0
SHIRPA	forelimb nail number	females	0.0 %	1.0
SHIRPA	forelimb nail number	males	0.0 %	1.0
SHIRPA	forelimb nail number	both	0.0 %	1.0
SHIRPA	forelimb nail position	females	0.0 %	1.0
SHIRPA	forelimb nail position	males	0.0 %	1.0
SHIRPA	forelimb nail position	both	0.0 %	1.0
SHIRPA	forelimb nail shape	females	0.0 %	1.0
SHIRPA	forelimb nail shape	males	0.0 %	1.0
SHIRPA	forelimb nail shape	both	0.0 %	1.0
SHIRPA	forelimbs position	females	0.0 %	1.0
SHIRPA	forelimbs position	males	0.0 %	1.0
SHIRPA	forelimbs position	both	0.0 %	1.0
SHIRPA	forelimbs shape	females	0.0 %	1.0
SHIRPA	forelimbs shape	males	0.0 %	1.0
SHIRPA	forelimbs shape	both	0.0 %	1.0
SHIRPA	forelimbs size	females	0.0 %	1.00
SHIRPA	forelimbs size	males	0.0 %	1.00
SHIRPA	forelimbs size	both	0.0 %	1.0
SHIRPA	forepaw position	females	0.0 %	1.0
SHIRPA	forepaw position	males	0.0 %	1.0
SHIRPA	forepaw position	both	0.0 %	1.0
SHIRPA	forepaw shape	females	0.0 %	1.0
SHIRPA	forepaw shape	males	0.0 %	1.0
SHIRPA	forepaw shape	both	0.0 %	1.0
SHIRPA	forepaw size	females	0.0 %	1.0
SHIRPA	forepaw size	males	0.0 %	1.0
SHIRPA	forepaw size	both	0.0 %	1.0
SHIRPA	gait (fluidity)	females	0.0 %	1.0
SHIRPA	gait (fluidity)	males	0.0 %	1.00
SHIRPA	gait (fluidity)	both	0.0 %	1.00
SHIRPA	genitalia morphology	females	0.0 %	1.00
SHIRPA	genitalia morphology	males	0.0 %	1.0
SHIRPA	genitalia morphology	both	0.0 %	1.0
SHIRPA	genitalia presence	females	0.0 %	1.00
SHIRPA	genitalia presence	males	0.0 %	1.0
SHIRPA	genitalia presence	both	0.0 %	1.0
SHIRPA	genitalia size	females	0.0 %	1.0
SHIRPA	genitalia size	males	0.0 %	1.00
SHIRPA	genitalia size	both	0.0 %	1.0
SHIRPA	head bobbing	females	0.0 %	1.0
SHIRPA	head bobbing	males	0.0 %	1.0
SHIRPA	head bobbing	both	0.0 %	1.0
SHIRPA	head morphology	females	0.0 %	1.00
SHIRPA	head morphology	males	0.0 %	1.0
SHIRPA	head morphology	both	0.0 %	1.0
SHIRPA	head size	females	0.0 %	1.0
SHIRPA	head size	males	0.0 %	1.0
SHIRPA	head size	both	0.0 %	1.00
SHIRPA	hindlimb digit number	females	1.0 %	1.00
SHIRPA	hindlimb digit number	males	0.0 %	1.0
SHIRPA	hindlimb digit number	both	0.0 %	1.00
SHIRPA	hindlimb digit position	females	0.0 %	1.00
SHIRPA	hindlimb digit position	males	0.0 %	1.0
SHIRPA	hindlimb digit position	both	0.0 %	1.0
SHIRPA	hindlimb digit shape	females	0.0 %	1.00
SHIRPA	hindlimb digit shape	males	0.0 %	1.00
SHIRPA	hindlimb digit shape	both	0.0 %	1.0
SHIRPA	hindlimb digit size	females	0.0 %	1.00
SHIRPA	hindlimb digit size	males	0.0 %	1.0
SHIRPA	hindlimb digit size	both	0.0 %	1.0
SHIRPA	hindlimb nail length	females	0.0 %	1.0
SHIRPA	hindlimb nail length	males	0.0 %	1.0
SHIRPA	hindlimb nail length	both	0.0 %	1.00
SHIRPA	hindlimb nail number	females	0.0 %	1.0
SHIRPA	hindlimb nail number	males	1.0 %	1.0
SHIRPA	hindlimb nail number	both	0.0 %	1.00
SHIRPA	hindlimb nail position	females	0.0 %	1.0
SHIRPA	hindlimb nail position	males	0.0 %	1.0
SHIRPA	hindlimb nail position	both	0.0 %	1.0
SHIRPA	hindlimb nail shape	females	0.0 %	1.0
SHIRPA	hindlimb nail shape	males	0.0 %	1.0
SHIRPA	hindlimb nail shape	both	0.0 %	1.0
SHIRPA	hindlimbs footpads	females	0.0 %	1.00
SHIRPA	hindlimbs footpads	males	0.0 %	1.0
SHIRPA	hindlimbs footpads	both	0.0 %	1.0
SHIRPA	hindlimbs position	females	0.0 %	1.0
SHIRPA	hindlimbs position	males	0.0 %	1.0
SHIRPA	hindlimbs position	both	0.0 %	1.0
SHIRPA	hindlimbs shape	females	0.0 %	1.0
SHIRPA	hindlimbs shape	males	0.0 %	1.0
SHIRPA	hindlimbs shape	both	0.0 %	1.0
SHIRPA	hindlimbs size	females	0.0 %	1.0
SHIRPA	hindlimbs size	males	0.0 %	1.0
SHIRPA	hindlimbs size	both	0.0 %	1.0
SHIRPA	hindpaw position	females	0.0 %	1.0
SHIRPA	hindpaw position	males	0.0 %	1.0
SHIRPA	hindpaw position	both	0.0 %	1.0
SHIRPA	hindpaw shape	females	0.0 %	1.00
SHIRPA	hindpaw shape	males	0.0 %	1.0
SHIRPA	hindpaw shape	both	0.0 %	1.0
SHIRPA	hindpaw size	females	0.0 %	1.00
SHIRPA	hindpaw size	males	0.0 %	1.0
SHIRPA	hindpaw size	both	0.0 %	1.0
SHIRPA	limb grasp	females	9.0 %	1.0
SHIRPA	limb grasp	males	6.0 %	1.00
SHIRPA	limb grasp	both	7.0 %	0.636
SHIRPA	lower lip morphology	females	0.0 %	1.00
SHIRPA	lower lip morphology	males	0.0 %	1.0
SHIRPA	lower lip morphology	both	0.0 %	1.0
SHIRPA	lower teeth appearance	females	0.0 %	1.0
SHIRPA	lower teeth appearance	males	0.0 %	1.0
SHIRPA	lower teeth appearance	both	0.0 %	1.0
SHIRPA	mouth morphology	females	0.0 %	1.0
SHIRPA	mouth morphology	males	0.0 %	1.00
SHIRPA	mouth morphology	both	0.0 %	1.00
SHIRPA	salivation	females	0.0 %	1.0
SHIRPA	salivation	males	0.0 %	1.0
SHIRPA	salivation	both	0.0 %	1.0
SHIRPA	skin color back paws	females	0.0 %	1.0
SHIRPA	skin color back paws	males	0.0 %	1.0
SHIRPA	skin color back paws	both	0.0 %	1.0
SHIRPA	skin color ear	females	0.0 %	1.0
SHIRPA	skin color ear	males	0.0 %	1.0
SHIRPA	skin color ear	both	0.0 %	1.0
SHIRPA	skin color front paws	females	0.0 %	1.0
SHIRPA	skin color front paws	males	0.0 %	1.0
SHIRPA	skin color front paws	both	0.0 %	1.0
SHIRPA	skin color snout	females	0.0 %	1.0
SHIRPA	skin color snout	males	0.0 %	1.0
SHIRPA	skin color snout	both	0.0 %	1.0
SHIRPA	skin color tail	females	0.0 %	1.0
SHIRPA	skin color tail	males	0.0 %	1.0
SHIRPA	skin color tail	both	0.0 %	1.0
SHIRPA	skin color whole body	females	0.0 %	1.00
SHIRPA	skin color whole body	males	0.0 %	1.0
SHIRPA	skin color whole body	both	0.0 %	1.0
SHIRPA	skin texture back paw	females	0.0 %	1.0
SHIRPA	skin texture back paw	males	0.0 %	1.0
SHIRPA	skin texture back paw	both	0.0 %	1.0
SHIRPA	skin texture ear	females	0.0 %	1.0
SHIRPA	skin texture ear	males	0.0 %	1.0
SHIRPA	skin texture ear	both	0.0 %	1.0
SHIRPA	skin texture front paws	females	0.0 %	1.0
SHIRPA	skin texture front paws	males	0.0 %	1.0
SHIRPA	skin texture front paws	both	0.0 %	1.0
SHIRPA	skin texture snout	females	0.0 %	1.0
SHIRPA	skin texture snout	males	0.0 %	1.0
SHIRPA	skin texture snout	both	0.0 %	1.0
SHIRPA	skin texture tail	females	0.0 %	1.0
SHIRPA	skin texture tail	males	0.0 %	1.0
SHIRPA	skin texture tail	both	0.0 %	1.0
SHIRPA	skin texture whole body	females	0.0 %	1.0
SHIRPA	skin texture whole body	males	0.0 %	1.0
SHIRPA	skin texture whole body	both	0.0 %	1.00
SHIRPA	snout size	females	0.0 %	1.00
SHIRPA	snout size	males	1.0 %	1.00
SHIRPA	snout size	both	0.0 %	1.0
SHIRPA	startle response	females	0.0 %	1.0
SHIRPA	startle response	males	0.0 %	1.0
SHIRPA	startle response	both	0.0 %	1.0
SHIRPA	tail curvature	females	0.0 %	1.0
SHIRPA	tail curvature	males	0.0 %	1.0
SHIRPA	tail curvature	both	0.0 %	1.0
SHIRPA	tail elevation	females	1.0 %	1.00
SHIRPA	tail elevation	males	2.0 %	1.0
SHIRPA	tail elevation	both	1.0 %	1.0
SHIRPA	tail length	females	0.0 %	1.00
SHIRPA	tail length	males	0.0 %	1.00
SHIRPA	tail length	both	0.0 %	1.0
SHIRPA	tail morphology	females	0.0 %	1.0
SHIRPA	tail morphology	males	0.0 %	1.00
SHIRPA	tail morphology	both	0.0 %	1.00
SHIRPA	tail presence	females	0.0 %	1.0
SHIRPA	tail presence	males	0.0 %	1.0
SHIRPA	tail presence	both	0.0 %	1.0
SHIRPA	tail shape	females	0.0 %	1.00
SHIRPA	tail shape	males	0.0 %	1.0
SHIRPA	tail shape	both	0.0 %	1.0
SHIRPA	tail thickness	females	0.0 %	1.0
SHIRPA	tail thickness	males	0.0 %	1.0
SHIRPA	tail thickness	both	0.0 %	1.0
SHIRPA	teeth presence	females	0.0 %	1.00
SHIRPA	teeth presence	males	0.0 %	1.00
SHIRPA	teeth presence	both	0.0 %	1.0
SHIRPA	transfer arousal	females	1.0 %	1.0
SHIRPA	transfer arousal	males	2.0 %	1.0
SHIRPA	transfer arousal	both	1.0 %	1.0
SHIRPA	tremor	females	0.0 %	1.00
SHIRPA	tremor	males	0.0 %	1.0
SHIRPA	tremor	both	0.0 %	1.0
SHIRPA	trunk curl	females	0.0 %	1.0
SHIRPA	trunk curl	males	0.0 %	1.00
SHIRPA	trunk curl	both	0.0 %	1.0
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	females	0.0 %	1.0
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	males	0.0 %	1.0
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	both	0.0 %	1.00
SHIRPA	upper lip morphology	females	0.0 %	1.0
SHIRPA	upper lip morphology	males	0.0 %	1.0
SHIRPA	upper lip morphology	both	0.0 %	1.0
SHIRPA	upper teeth appearance	females	0.0 %	1.00
SHIRPA	upper teeth appearance	males	0.0 %	1.00
SHIRPA	upper teeth appearance	both	0.0 %	1.0
SHIRPA	vibrissae appearance	females	2.0 %	1.0
SHIRPA	vibrissae appearance	males	1.0 %	1.0
SHIRPA	vibrissae appearance	both	1.0 %	1.0
SHIRPA	vibrissae presence	females	2.0 %	1.0
SHIRPA	vibrissae presence	males	1.0 %	1.00
SHIRPA	vibrissae presence	both	2.0 %	1.00
SHIRPA	vocalization	females	2.0 %	1.0
SHIRPA	vocalization	males	2.0 %	1.0
SHIRPA	vocalization	both	2.0 %	1.0

GENOTYPE CORRELATION PLOT

Correlate Rai14^em1(IMPC)J -/+ with genotype: