MPD: JaxKOMP-EAP genotype: Ofcc1<sup>em1(IMPC)J</sup> -/-

JaxKOMP-EAP effect sizes: Ofcc1^em1(IMPC)J -/- Gene Ofcc1

MULTIPLE (NUMERIC) TRAIT PROFILE PLOT — Early Adult Phenotyping study (EAP)

Procedure	JaxKOMP-EAP Trait	Trait Effect	Trait Effect SE	Trait Effect RankZ	Adjusted p-value	Unadjusted p-value
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 6 kHz pip	0.29183	4.0270	-0.20013	0.984	0.947
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 12 kHz pip	-3.3750	5.4952	-0.74047	0.878	0.583
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 18 kHz pip	1.8899	2.6975	0.24309	0.819	0.534
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 24 kHz pip	-13.314	10.912	-1.8761	0.684	0.310
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 30 kHz pip	-11.607	9.4171	-1.5020	0.667	0.306
body composition	body length	0.055844	0.030405	0.93965	0.283	0.0722
body composition	body weight (at time of DXA)	0.99440	0.59800	0.90024	0.269	0.102
body composition	bone area, whole body scan, head excluded	0.19483	0.11104	1.0165	0.296	0.0855
body composition	bone mineral content of whole body scan, head excluded	0.0086675	0.0091328	0.64059	0.635	0.347
body composition	bone mineral content to body weight ratio	0.000062890	0.00036753	0.23984	0.944	0.865
body composition	bone mineral density of whole body scan, head excluded	-0.000037872	0.00050314	-0.017076	0.983	0.940
body composition	fat tissue mass of whole body scan, head excluded	-0.32011	0.27797	-0.59271	0.503	0.255
body composition	fat tissue mass to body weight ratio	-0.011771	0.0097932	-0.50383	0.465	0.235
body composition	lean tissue mass of whole body scan, head excluded	0.35498	0.26324	0.58946	0.491	0.184
body composition	lean tissue mass to body weight ratio	0.0014576	0.0092153	0.017076	0.936	0.875
body composition	percent fat, whole body scan, head excluded	-1.0233	0.94287	-0.47002	0.532	0.283
body composition	ratio of soft-tissue attenuation coefficients	0.0010940	0.0010535	0.44227	0.555	0.304
body composition	tissue area	0.043802	0.13590	0.32980	0.911	0.749
body composition	total tissue mass, whole body scan, head excluded	0.031465	0.13829	-0.14661	0.915	0.821
clinical blood chemistry	alanine transaminase (plasma ALT)	-14.368	28.547	-1.1210	0.874	0.618
clinical blood chemistry	albumin (plasma Alb)	-0.27738	0.51645	-0.34614	0.842	0.594
clinical blood chemistry	alkaline phosphatase (plasma ALP)	0.29240	3.1599	-0.48210	0.965	0.927
clinical blood chemistry	aspartate transaminase (plasma AST)	-23.149	19.987	-1.0369	0.567	0.254
clinical blood chemistry	aspartate transaminase to alanine transaminase ratio (plasma AST:ALT)	0.023904	0.26803	0.10380	0.981	0.929
clinical blood chemistry	blood urea nitrogen (BUN)	0.49315	0.82173	0.17939	0.762	0.552
clinical blood chemistry	calcium (plasma Ca)	-0.13019	0.078478	-0.58561	0.293	0.106
clinical blood chemistry	creatinine (plasma)	0.020128	0.023730	0.60369	0.637	0.402
clinical blood chemistry	glucose (plasma GLU, no fast)	-13.807	12.004	-0.24892	0.462	0.257
clinical blood chemistry	HDL cholesterol (plasma HDL)	1.7185	2.6612	0.077302	0.775	0.522
clinical blood chemistry	HDL cholesterol to total cholesterol ratio	-0.0038389	0.0086835	-0.38893	0.884	0.661
clinical blood chemistry	phosphorus (plasma phosphate)	-0.52041	0.32862	-0.89098	0.361	0.122
clinical blood chemistry	total bilirubin (plasma TBIL)	0.0064383	0.0066564	0.43488	0.689	0.340
clinical blood chemistry	total cholesterol (plasma CHOL, no fast)	2.1751	3.2072	0.16208	0.773	0.502
clinical blood chemistry	total protein (plasma TP)	0.15839	0.60163	0.052841	0.906	0.794
clinical blood chemistry	triglyceride (plasma TG, no fast)	-10.384	4.8718	-0.36261	0.204	0.0398
EKG	duration of PQ interval	-0.29111	0.56400	-0.17007	0.924	0.608
EKG	duration of PR interval	-0.39111	0.62459	-0.30911	0.913	0.535
EKG	duration of QRS interval	-0.035556	0.28869	-0.23384	0.990	0.903
EKG	duration of QT interval	0.87619	0.56025	0.99129	0.644	0.126
EKG	duration of QTC interval, calculated by dividing QT interval by square root of preceding RR interval	0.90375	0.53435	1.0046	0.687	0.0984
EKG	duration of RR interval	0.59889	1.0733	0.57408	0.840	0.580
EKG	duration of ST interval	0.76321	0.63999	1.0046	0.735	0.240
EKG	heart rate coefficient of variation (signal intensity)	-0.14544	0.79604	-0.016120	0.971	0.856
EKG	heart rate variability, mean of differences between sequential beats; beats per min	-1.4042	5.6373	-0.062505	0.969	0.805
EKG	heart rate, beats per min	-4.9333	9.1598	-0.57816	0.836	0.593
EKG	mean R amplitude, mean amplitude of signal measured from isoelectric line to peak of QRS	0.15464	0.072859	1.0590	0.285	0.0397
EKG	mean SR amplitude, mean amplitude of signal measured from signal minimum line to peak of QRS	0.19454	0.093186	1.0484	0.290	0.0429
EKG	number of signals	3.3778	3.8899	0.63455	0.832	0.390
EKG	proportion of number pairs of successive beat-to-beat intervals that exceed 50 ms	2.9746	3.9878	0.62920	0.858	0.460
EKG	QT dispersion, measured as inter-lead variability of QT intervals	-1.1587	2.3305	-0.31546	0.964	0.622
EKG	QTc dispersion, calculated as rate-corrected QT dispersion	-0.72346	2.2984	-0.17621	0.966	0.754
EKG	root mean square of successive differences of neighboring RR intervals	0.36020	1.1269	0.29856	0.947	0.751
glucose tolerance test	amount glucose injected	-0.91882	2.3340	0.073629	0.904	0.696
glucose tolerance test	plasma glucose, 0min	-1.8665	4.8185	-0.41372	0.842	0.700
glucose tolerance test	plasma glucose, 15min	-49.706	22.675	-1.2558	0.221	0.0340
glucose tolerance test	plasma glucose, 30min	-43.290	23.895	-1.1644	0.340	0.0774
glucose tolerance test	plasma glucose, 60min	-4.1119	18.219	-0.037073	0.929	0.823
glucose tolerance test	plasma glucose, 120min	9.2643	12.412	0.50372	0.721	0.460
grip strength	body weight (at time of grip strength test)	-0.81904	0.49342	-0.53341	0.248	0.105
grip strength	forelimb and hindlimb grip strength (mean of trials), average	-31.795	7.8809	-1.8541	0.00480	0.000273
grip strength	forelimb and hindlimb grip strength (mean of trials), average normalized to bw	-1.4478	0.39085	-1.7510	0.00975	0.000689
grip strength	forelimb and hindlimb grip strength by trial, trial1	-29.640	8.9700	-1.6299	0.0339	0.00216
grip strength	forelimb and hindlimb grip strength by trial, trial2	-35.206	10.516	-1.9615	0.0315	0.00192
grip strength	forelimb and hindlimb grip strength by trial, trial3	-30.509	9.2383	-1.6354	0.0319	0.00217
grip strength	forelimb grip strength (mean of trials), average	-9.4448	5.1372	-0.86503	0.260	0.0740
grip strength	forelimb grip strength (mean of trials), average normalized to bw	-0.37815	0.26737	-0.72930	0.422	0.166
grip strength	forelimb grip strength by trial, trial1	0.29587	6.8755	0.31444	0.985	0.966
grip strength	forelimb grip strength by trial, trial2	-6.1592	6.9524	-0.43764	0.701	0.382
grip strength	forelimb grip strength by trial, trial3	-20.752	6.1979	-1.8150	0.0494	0.00188
heart weight	heart weight, normalized to body weight	0.0035966	0.19749	-0.44312	0.991	0.986
heart weight	heart weight, weight	7.1075	2.6838	0.54545	0.0698	0.0108
hematology	basophil differential (percent of total WBC)	-0.12373	0.056204	-1.4957	0.352	0.0337
hematology	calculated hemoglobin (cHGB)	-0.19960	0.14783	-0.86514	0.462	0.185
hematology	eosinophil differential (percent of total WBC)	-0.10328	0.23083	-0.21847	0.888	0.657
hematology	hematocrit (HCT)	-1.0403	0.47984	-1.2890	0.223	0.0363
hematology	hemoglobin concentration distribution width (HDW)	0.0068568	0.023176	0.19062	0.898	0.769
hematology	large unstained cells (percent of total WBC)	0.016524	0.085914	0.12102	0.934	0.848
hematology	lymphocyte differential (percent of total WBC)	2.1208	2.5392	0.74212	0.637	0.409
hematology	mean corpuscular hemoglobin (CHr)	-0.023039	0.061301	-0.17159	0.859	0.709
hematology	mean platelet volume (MPV)	-0.020083	0.062046	-0.34346	0.874	0.748
hematology	mean RBC corpuscular hemoglobin (MCH)	-0.0088034	0.15936	-0.063623	0.979	0.956
hematology	mean RBC corpuscular hemoglobin concentration (MCHC)	0.32800	0.39273	0.70314	0.745	0.409
hematology	mean RBC corpuscular volume (MCV)	-0.55442	0.30505	-0.97766	0.222	0.0768
hematology	measured hemoglobin (mHGB)	-0.15766	0.22320	-0.62425	0.725	0.484
hematology	monocyte differential (percent of total WBC)	-0.25235	0.13179	-0.61972	0.361	0.0629
hematology	neutrophil differential (percent of total WBC)	-1.6078	2.5098	-0.71186	0.725	0.526
hematology	platelet count (PLT; units per volume x 10³)	27.876	35.145	0.42973	0.749	0.433
hematology	RBC corpuscular distribution width (RDW)	0.13333	0.18422	0.44531	0.703	0.474
hematology	RBC corpuscular hemoglobin concentration mean (CHCM)	0.29741	0.17239	0.72112	0.282	0.0924
hematology	red blood cell count (RBC; per volume x 10⁶)	-0.096103	0.10653	-0.73949	0.642	0.373
hematology	reticulocyte count (Retic; units per volume x 10⁹)	-1.7684	13.036	0.0061808	0.973	0.893
hematology	reticulocyte differential (percent of total RBC)	0.015361	0.15913	0.27971	0.975	0.924
hematology	white blood cell count (WBC; units per volume x 10³)	0.16544	0.51946	0.31110	0.864	0.752
holeboard	number of hole pokes by individual hole number, 20 min test, 1	-1.6620	0.53929	-1.5610	0.178	0.00347
holeboard	number of hole pokes by individual hole number, 20 min test, 2	-0.62048	0.49733	-0.82017	0.734	0.218
holeboard	number of hole pokes by individual hole number, 20 min test, 3	0.31434	0.41228	0.61883	0.860	0.450
holeboard	number of hole pokes by individual hole number, 20 min test, 4	-0.46165	0.66525	-0.38668	0.849	0.491
holeboard	number of hole pokes by individual hole number, 20 min test, 5	-0.25620	0.45651	-0.30601	0.897	0.577
holeboard	number of hole pokes by individual hole number, 20 min test, 6	0.16487	0.27499	0.49139	0.924	0.552
holeboard	number of hole pokes by individual hole number, 20 min test, 7	0.27190	0.23919	0.71047	0.835	0.262
holeboard	number of hole pokes by individual hole number, 20 min test, 8	0.064665	0.67766	0.24464	0.986	0.924
holeboard	number of hole pokes by individual hole number, 20 min test, 9	-0.64388	0.44508	-0.99845	0.620	0.155
holeboard	number of hole pokes by individual hole number, 20 min test, 10	-0.61042	0.39484	-1.6390	0.728	0.129
holeboard	number of hole pokes by individual hole number, 20 min test, 11	-0.65335	0.58829	-1.7304	0.807	0.273
holeboard	number of hole pokes by individual hole number, 20 min test, 12	-0.58348	0.41574	-0.89122	0.616	0.167
holeboard	number of hole pokes by individual hole number, 20 min test, 13	-1.4884	0.60959	-1.4000	0.353	0.0185
holeboard	number of hole pokes by individual hole number, 20 min test, 14	-1.2082	0.43273	-1.8574	0.267	0.00766
holeboard	number of hole pokes by individual hole number, 20 min test, 15	-0.40580	0.48679	-0.55327	0.815	0.409
holeboard	number of hole pokes by individual hole number, 20 min test, 16	0.14819	0.64434	0.15923	0.948	0.819
holeboard	total number of hole pokes, 20 min test	-7.9940	3.4280	-1.0684	0.169	0.0241
light / dark	fecal boli count, 20 min test	-1.2647	0.77603	-1.4044	0.508	0.113
light / dark	latency to enter dark zone, 20 min test	-53.389	36.770	-1.1013	0.587	0.156
light / dark	number of transitions between light and dark zones, 20 min test	12.083	9.1795	1.1899	0.522	0.197
light / dark	percentage of total time in dark zone, 20 min test	-15.126	4.1420	-2.1818	0.0462	0.000893
light / dark	percentage of total time in light zone, 20 min test	15.126	4.1420	2.1674	0.0449	0.000893
light / dark	time mobile in dark zone, 20 min test	-7.9160	13.333	-0.61539	0.802	0.557
light / dark	time mobile in light zone, 20 min test	42.270	11.336	1.7332	0.0131	0.000721
light / dark	time spent in dark zone, 20 min test	-140.78	49.801	-1.6754	0.155	0.00804
light / dark	time spent in light zone, 20 min test	140.78	49.801	1.6754	0.155	0.00804
open field	average speed in center of arena, 20 min test	0.23844	0.34975	0.33723	0.793	0.499
open field	average speed in periphery of arena, 20 min test	0.10543	0.14720	-0.081317	0.698	0.477
open field	distance traveled habituation ratio, 20 min test	-9.6459	6.7605	-0.79914	0.475	0.160
open field	distance traveled in center of arena, 20 min test	102.72	70.520	0.32872	0.385	0.152
open field	distance traveled in periphery of arena, 20 min test	83.961	158.41	-0.090750	0.778	0.599
open field	distance traveled slope, 20 min test	-8.7019	6.4090	-0.76451	0.502	0.181
open field	distance traveled, 20 min test, 1st 5min	98.328	72.888	0.45343	0.412	0.184
open field	distance traveled, 20 min test, 2nd 5min	46.442	52.770	0.026184	0.624	0.383
open field	distance traveled, 20 min test, 3rd 5min	40.474	48.099	0.015440	0.653	0.404
open field	distance traveled, 20 min test, 4th 5min	1.5829	49.268	-0.44304	0.988	0.975
open field	number of clockwise revolution episodes, 20 min test	0.41362	1.0602	-0.17007	0.890	0.698
open field	number of counter-clockwise revolution episodes, 20 min test	1.2601	1.1529	0.25307	0.561	0.280
open field	number of fecal boli, 20 min test	-1.4119	0.84987	-0.89589	0.391	0.105
open field	number of rears in 5 min bins, 20 min test, 1st 5min	2.8006	1.9852	0.56460	0.417	0.165
open field	number of rears in 5 min bins, 20 min test, 2nd 5min	1.6622	2.0949	0.063817	0.699	0.432
open field	number of rears in 5 min bins, 20 min test, 3rd 5min	4.4304	2.1104	0.71508	0.199	0.0412
open field	number of rears in 5 min bins, 20 min test, 4th 5min	6.0879	2.4791	0.99164	0.142	0.0179
open field	percentage of total time in center of arena, 20 min test	-0.092131	3.1795	-0.22131	0.994	0.977
open field	percentage of total time in center of arena, slope, 20 min test	2.5084	1.6877	1.5241	0.594	0.144
open field	percentage of total time in center, habituation ratio, 20 min test	2.3785	1.7816	1.4247	0.668	0.188
open field	percentage of total time in corners of arena, 20 min test	-5.3888	3.5669	-0.70128	0.440	0.138
open field	percentage of total time in corners, habituation ratio, 20 min test	-1.6128	2.0016	-1.0343	0.849	0.424
open field	percentage of total time in corners, slope, 20 min test	-1.8002	1.9794	-1.1231	0.813	0.368
open field	permanence time in center of arena, 20 min test	-1.1217	38.153	-0.21993	0.994	0.977
open field	permanence time in corners of arena, 20 min test	-64.651	42.802	-0.70128	0.440	0.138
open field	permanence time in periphery of arena, 20 min test	1.0979	38.146	0.21856	0.994	0.977
open field	total distance traveled, 20 min test	186.67	187.38	0.075930	0.549	0.324
open field	total number of rears, 20 min test	16.481	7.2521	0.78810	0.141	0.0277
open field	whole arena average speed, 20 min test	0.15678	0.15610	0.078623	0.546	0.320
open field	whole arena resting time, 20 min test	-27.296	18.099	-0.22131	0.306	0.138
open field	whole arena time spent mobile, 20 min test	27.304	18.097	0.47586	0.311	0.138
open field	whole arena time spent vertical, 20 min test	14.519	7.9283	1.0320	0.313	0.0735
SHIRPA	locomotor activity (number of squares in the arena the mouse moves into with all four paws in first 30 s of test)	1.8285	1.6804	0.96156	0.597	0.284
startle / PPI	average baseline movement during background noise	3.2589	0.98366	1.7414	0.188	0.00168
startle / PPI	average of each corrected maximum percent pre-pulse inhibition value	-0.12377	0.062004	-1.2054	0.312	0.0512
startle / PPI	average of each corrected percent pre-pulse inhibition value	-0.13567	0.057848	-1.4012	0.221	0.0229
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-11.378	7.5162	-1.1939	0.843	0.136
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-17.174	6.0664	-1.6866	0.157	0.00658
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-12.116	5.3101	-1.2470	0.175	0.0266
startle / PPI	average startle response to full pulse (120 dB)	-5.5450	24.118	0.058180	0.932	0.819
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	15.975	24.405	0.54168	0.727	0.516
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	31.377	21.271	0.84322	0.348	0.146
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	23.632	17.551	0.76013	0.393	0.184
startle / PPI	average startle response to pre-pulse, 74dB sound pressure level	2.9954	0.99313	1.5706	0.295	0.00396
startle / PPI	average startle response to pre-pulse, 78dB sound pressure level	-0.66389	0.97144	-0.44203	0.891	0.497
startle / PPI	average startle response to pre-pulse, 82dB sound pressure level	3.7079	1.5074	1.2470	0.240	0.0173
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-0.12944	0.082801	-1.1253	0.794	0.124
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-0.19857	0.065384	-1.6979	0.109	0.00373
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-0.098938	0.062073	-0.91290	0.333	0.117
startle / PPI	corrected average startle response to full pulse (120 dB) minus average baseline movement during background noise	-8.3858	24.369	0.0049040	0.879	0.732
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 74dB sound pressure level	12.980	24.604	0.47628	0.787	0.600
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 78dB sound pressure level	32.041	21.353	0.84122	0.340	0.140
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 82dB sound pressure level	19.990	17.968	0.66266	0.488	0.271
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-0.16385	0.091412	-1.2973	0.751	0.0789
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-0.14328	0.071283	-1.1850	0.300	0.0496
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-0.086853	0.064381	-0.81319	0.439	0.183
startle / PPI	corrected maximum startle response to full pulse (120 dB) minus maximum baseline movement during background noise	-40.042	89.784	-0.048358	0.841	0.657
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 74dB sound pressure level	72.437	90.454	0.56454	0.646	0.427
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 78dB sound pressure level	79.346	78.088	0.62474	0.534	0.314
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 82dB sound pressure level	63.386	67.863	0.58770	0.567	0.355
startle / PPI	maximum baseline movement during background noise	7.5344	2.2126	1.6473	0.220	0.00128
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-15.359	8.6845	-1.3980	0.781	0.0828
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-12.745	6.8380	-1.1685	0.374	0.0680
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-10.510	5.8030	-1.0397	0.296	0.0759
startle / PPI	maximum startle response to full pulse (120 dB)	-33.848	89.417	-0.018916	0.869	0.707
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	78.441	90.150	0.58603	0.610	0.388
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	77.714	77.740	0.61286	0.538	0.322
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	72.514	66.814	0.62986	0.502	0.283
startle / PPI	maximum startle response to pre-pulse, 74dB sound pressure level	5.5492	2.0907	1.3760	0.366	0.0105
startle / PPI	maximum startle response to pre-pulse, 78dB sound pressure level	-1.6408	2.2954	-0.42663	0.849	0.478
startle / PPI	maximum startle response to pre-pulse, 82dB sound pressure level	9.1283	4.1396	1.1939	0.296	0.0319

MULTIPLE (CATEGORICAL) TRAIT PROFILE PLOT — Early Adult Phenotyping study (EAP)

Procedure	JaxKOMP-EAP Trait	Sex	Trait Effect	P-value
eye morphology	anterior chamber depth	females	1.0 %	1.0
eye morphology	anterior chamber depth	males	0.0 %	1.0
eye morphology	anterior chamber depth	both	1.0 %	1.0
eye morphology	bulging eye	females	1.0 %	1.0
eye morphology	bulging eye	males	0.0 %	1.0
eye morphology	bulging eye	both	1.0 %	1.00
eye morphology	cornea	females	4.0 %	1.0
eye morphology	cornea	males	2.0 %	1.0
eye morphology	cornea	both	3.0 %	1.00
eye morphology	cornea opacity	females	5.0 %	1.0
eye morphology	cornea opacity	males	1.0 %	1.0
eye morphology	cornea opacity	both	3.0 %	1.0
eye morphology	cornea vascularization	females	3.0 %	1.0
eye morphology	cornea vascularization	males	1.0 %	1.0
eye morphology	cornea vascularization	both	2.0 %	1.0
eye morphology	corneal deposits	females	2.0 %	1.0
eye morphology	corneal deposits	males	1.0 %	1.0
eye morphology	corneal deposits	both	1.0 %	1.00
eye morphology	corneal mineralization	females	2.0 %	1.0
eye morphology	corneal mineralization	males	1.0 %	1.0
eye morphology	corneal mineralization	both	1.0 %	1.00
eye morphology	corneal scleralization	females	3.0 %	1.0
eye morphology	corneal scleralization	males	1.0 %	1.0
eye morphology	corneal scleralization	both	2.0 %	1.0
eye morphology	corneal ulcer	females	1.0 %	1.0
eye morphology	corneal ulcer	males	1.0 %	1.0
eye morphology	corneal ulcer	both	1.0 %	1.00
eye morphology	eye closure	females	1.0 %	1.0
eye morphology	eye closure	males	0.0 %	1.0
eye morphology	eye closure	both	1.0 %	1.00
eye morphology	eye hemorrhage or blood presence	females	2.0 %	1.0
eye morphology	eye hemorrhage or blood presence	males	1.0 %	1.0
eye morphology	eye hemorrhage or blood presence	both	1.0 %	1.0
eye morphology	eyelid morphology	females	1.0 %	1.00
eye morphology	eyelid morphology	males	0.0 %	1.0
eye morphology	eyelid morphology	both	1.0 %	1.00
eye morphology	eyes (present, absent)	females	1.0 %	1.00
eye morphology	eyes (present, absent)	males	0.0 %	1.0
eye morphology	eyes (present, absent)	both	0.0 %	1.00
eye morphology	fusion between cornea and lens	females	4.0 %	1.0
eye morphology	fusion between cornea and lens	males	2.0 %	1.0
eye morphology	fusion between cornea and lens	both	3.0 %	1.0
eye morphology	iris pigmentation	females	33.0 %	0.0110
eye morphology	iris pigmentation	males	1.0 %	1.0
eye morphology	iris pigmentation	both	17.0 %	0.0260
eye morphology	iris transillumination	females	2.0 %	1.0
eye morphology	iris transillumination	males	1.0 %	1.00
eye morphology	iris transillumination	both	1.0 %	1.00
eye morphology	irispupil	females	4.0 %	1.0
eye morphology	irispupil	males	3.0 %	1.0
eye morphology	irispupil	both	3.0 %	1.0
eye morphology	lacrimation	females	3.0 %	1.0
eye morphology	lacrimation	males	2.0 %	1.0
eye morphology	lacrimation	both	3.0 %	1.00
eye morphology	lens	females	10.0 %	1.0
eye morphology	lens	males	8.0 %	1.00
eye morphology	lens	both	9.0 %	1.00
eye morphology	lens opacity	females	9.0 %	1.0
eye morphology	lens opacity	males	6.0 %	1.0
eye morphology	lens opacity	both	7.0 %	1.00
eye morphology	narrow eye opening	females	2.0 %	1.00
eye morphology	narrow eye opening	males	1.0 %	1.0
eye morphology	narrow eye opening	both	1.0 %	1.00
eye morphology	optic disc	females	4.0 %	1.0
eye morphology	optic disc	males	2.0 %	1.0
eye morphology	optic disc	both	3.0 %	1.00
eye morphology	persistence of hyaloid vascular system	females	14.0 %	1.0
eye morphology	persistence of hyaloid vascular system	males	5.0 %	1.0
eye morphology	persistence of hyaloid vascular system	both	9.0 %	1.00
eye morphology	pupil dilation	females	2.0 %	1.0
eye morphology	pupil dilation	males	1.0 %	1.0
eye morphology	pupil dilation	both	2.0 %	1.00
eye morphology	pupil light response	females	2.0 %	1.0
eye morphology	pupil light response	males	1.0 %	1.0
eye morphology	pupil light response	both	2.0 %	1.0
eye morphology	pupil position	females	4.0 %	1.0
eye morphology	pupil position	males	3.0 %	1.0
eye morphology	pupil position	both	4.0 %	1.0
eye morphology	pupil shape	females	3.0 %	1.0
eye morphology	pupil shape	males	2.0 %	1.0
eye morphology	pupil shape	both	3.0 %	1.0
eye morphology	retina	females	10.0 %	1.00
eye morphology	retina	males	16.0 %	1.0
eye morphology	retina	both	13.0 %	1.00
eye morphology	retinal blood vessels	females	4.0 %	1.0
eye morphology	retinal blood vessels	males	2.0 %	1.0
eye morphology	retinal blood vessels	both	3.0 %	1.00
eye morphology	retinal blood vessels pattern	females	5.0 %	1.0
eye morphology	retinal blood vessels pattern	males	2.0 %	1.00
eye morphology	retinal blood vessels pattern	both	4.0 %	1.00
eye morphology	retinal blood vessels structure	females	4.0 %	1.0
eye morphology	retinal blood vessels structure	males	2.0 %	1.0
eye morphology	retinal blood vessels structure	both	3.0 %	1.0
eye morphology	retinal pigmentation	females	12.0 %	1.00
eye morphology	retinal pigmentation	males	14.0 %	1.0
eye morphology	retinal pigmentation	both	13.0 %	1.00
eye morphology	retinal structure	females	4.0 %	1.0
eye morphology	retinal structure	males	2.0 %	1.00
eye morphology	retinal structure	both	3.0 %	1.00
eye morphology	synechia	females	4.0 %	1.0
eye morphology	synechia	males	2.0 %	1.0
eye morphology	synechia	both	3.0 %	1.00
eye morphology	vitreous	females	4.0 %	1.0
eye morphology	vitreous	males	2.0 %	1.0
eye morphology	vitreous	both	3.0 %	1.0
SHIRPA	activity body position	females	1.0 %	1.0
SHIRPA	activity body position	males	2.0 %	1.0
SHIRPA	activity body position	both	1.0 %	1.00
SHIRPA	aggression	females	0.0 %	1.00
SHIRPA	aggression	males	1.0 %	1.0
SHIRPA	aggression	both	1.0 %	1.0
SHIRPA	body length	females	0.0 %	1.00
SHIRPA	body length	males	0.0 %	1.00
SHIRPA	body length	both	0.0 %	1.00
SHIRPA	body position	females	0.0 %	1.00
SHIRPA	body position	males	1.0 %	1.0
SHIRPA	body position	both	0.0 %	1.0
SHIRPA	body thickness	females	1.0 %	1.0
SHIRPA	body thickness	males	0.0 %	1.0
SHIRPA	body thickness	both	0.0 %	1.0
SHIRPA	coat color abdomen	females	3.0 %	1.00
SHIRPA	coat color abdomen	males	4.0 %	1.0
SHIRPA	coat color abdomen	both	4.0 %	1.0
SHIRPA	coat color back	females	0.0 %	1.00
SHIRPA	coat color back	males	0.0 %	1.0
SHIRPA	coat color back	both	0.0 %	1.00
SHIRPA	coat color head	females	0.0 %	1.00
SHIRPA	coat color head	males	0.0 %	1.0
SHIRPA	coat color head	both	0.0 %	1.0
SHIRPA	coat color pattern abdomen	females	1.0 %	1.00
SHIRPA	coat color pattern abdomen	males	1.0 %	1.00
SHIRPA	coat color pattern abdomen	both	1.0 %	1.00
SHIRPA	coat color pattern back	females	0.0 %	1.00
SHIRPA	coat color pattern back	males	0.0 %	1.0
SHIRPA	coat color pattern back	both	0.0 %	1.0
SHIRPA	coat color pattern head	females	0.0 %	1.00
SHIRPA	coat color pattern head	males	0.0 %	1.00
SHIRPA	coat color pattern head	both	0.0 %	1.00
SHIRPA	coat hair abdomen texture appearance	females	2.0 %	1.0
SHIRPA	coat hair abdomen texture appearance	males	2.0 %	1.0
SHIRPA	coat hair abdomen texture appearance	both	2.0 %	1.0
SHIRPA	coat hair back texture appearance	females	0.0 %	1.0
SHIRPA	coat hair back texture appearance	males	0.0 %	1.0
SHIRPA	coat hair back texture appearance	both	0.0 %	1.0
SHIRPA	coat hair distribution abdomen	females	0.0 %	1.00
SHIRPA	coat hair distribution abdomen	males	1.0 %	1.0
SHIRPA	coat hair distribution abdomen	both	1.0 %	1.0
SHIRPA	coat hair distribution back	females	0.0 %	1.00
SHIRPA	coat hair distribution back	males	0.0 %	1.00
SHIRPA	coat hair distribution back	both	0.0 %	1.0
SHIRPA	coat hair distribution head	females	1.0 %	1.00
SHIRPA	coat hair distribution head	males	1.0 %	1.0
SHIRPA	coat hair distribution head	both	1.0 %	1.0
SHIRPA	coat hair head texture appearance	females	0.0 %	1.00
SHIRPA	coat hair head texture appearance	males	0.0 %	1.0
SHIRPA	coat hair head texture appearance	both	0.0 %	1.0
SHIRPA	contact righting	females	5.0 %	1.0
SHIRPA	contact righting	males	5.0 %	1.0
SHIRPA	contact righting	both	5.0 %	0.624
SHIRPA	ear morphology	females	0.0 %	1.0
SHIRPA	ear morphology	males	0.0 %	1.0
SHIRPA	ear morphology	both	0.0 %	1.0
SHIRPA	fat distribution	females	0.0 %	1.00
SHIRPA	fat distribution	males	0.0 %	1.0
SHIRPA	fat distribution	both	0.0 %	1.00
SHIRPA	forelimb digit number	females	0.0 %	1.00
SHIRPA	forelimb digit number	males	0.0 %	1.0
SHIRPA	forelimb digit number	both	0.0 %	1.00
SHIRPA	forelimb digit position	females	0.0 %	1.0
SHIRPA	forelimb digit position	males	0.0 %	1.0
SHIRPA	forelimb digit position	both	0.0 %	1.0
SHIRPA	forelimb digit shape	females	0.0 %	1.0
SHIRPA	forelimb digit shape	males	0.0 %	1.0
SHIRPA	forelimb digit shape	both	0.0 %	1.0
SHIRPA	forelimb digit size	females	0.0 %	1.0
SHIRPA	forelimb digit size	males	0.0 %	1.0
SHIRPA	forelimb digit size	both	0.0 %	1.0
SHIRPA	forelimb footpads	females	0.0 %	1.00
SHIRPA	forelimb footpads	males	0.0 %	1.0
SHIRPA	forelimb footpads	both	0.0 %	1.0
SHIRPA	forelimb nail length	females	0.0 %	1.0
SHIRPA	forelimb nail length	males	0.0 %	1.0
SHIRPA	forelimb nail length	both	0.0 %	1.0
SHIRPA	forelimb nail number	females	0.0 %	1.0
SHIRPA	forelimb nail number	males	0.0 %	1.0
SHIRPA	forelimb nail number	both	0.0 %	1.0
SHIRPA	forelimb nail position	females	0.0 %	1.0
SHIRPA	forelimb nail position	males	0.0 %	1.0
SHIRPA	forelimb nail position	both	0.0 %	1.0
SHIRPA	forelimb nail shape	females	0.0 %	1.0
SHIRPA	forelimb nail shape	males	0.0 %	1.0
SHIRPA	forelimb nail shape	both	0.0 %	1.0
SHIRPA	forelimbs position	females	0.0 %	1.0
SHIRPA	forelimbs position	males	0.0 %	1.0
SHIRPA	forelimbs position	both	0.0 %	1.0
SHIRPA	forelimbs shape	females	0.0 %	1.0
SHIRPA	forelimbs shape	males	0.0 %	1.0
SHIRPA	forelimbs shape	both	0.0 %	1.0
SHIRPA	forelimbs size	females	0.0 %	1.00
SHIRPA	forelimbs size	males	0.0 %	1.00
SHIRPA	forelimbs size	both	0.0 %	1.0
SHIRPA	forepaw position	females	0.0 %	1.0
SHIRPA	forepaw position	males	0.0 %	1.0
SHIRPA	forepaw position	both	0.0 %	1.0
SHIRPA	forepaw shape	females	0.0 %	1.0
SHIRPA	forepaw shape	males	0.0 %	1.0
SHIRPA	forepaw shape	both	0.0 %	1.0
SHIRPA	forepaw size	females	0.0 %	1.0
SHIRPA	forepaw size	males	0.0 %	1.0
SHIRPA	forepaw size	both	0.0 %	1.0
SHIRPA	gait (fluidity)	females	0.0 %	1.0
SHIRPA	gait (fluidity)	males	0.0 %	1.00
SHIRPA	gait (fluidity)	both	0.0 %	1.00
SHIRPA	genitalia morphology	females	0.0 %	1.00
SHIRPA	genitalia morphology	males	0.0 %	1.0
SHIRPA	genitalia morphology	both	0.0 %	1.0
SHIRPA	genitalia presence	females	0.0 %	1.00
SHIRPA	genitalia presence	males	0.0 %	1.0
SHIRPA	genitalia presence	both	0.0 %	1.0
SHIRPA	genitalia size	females	0.0 %	1.0
SHIRPA	genitalia size	males	0.0 %	1.00
SHIRPA	genitalia size	both	0.0 %	1.0
SHIRPA	head bobbing	females	0.0 %	1.0
SHIRPA	head bobbing	males	0.0 %	1.0
SHIRPA	head bobbing	both	0.0 %	1.0
SHIRPA	head morphology	females	0.0 %	1.00
SHIRPA	head morphology	males	0.0 %	1.0
SHIRPA	head morphology	both	0.0 %	1.0
SHIRPA	head size	females	0.0 %	1.0
SHIRPA	head size	males	0.0 %	1.0
SHIRPA	head size	both	0.0 %	1.00
SHIRPA	hindlimb digit number	females	1.0 %	1.00
SHIRPA	hindlimb digit number	males	0.0 %	1.0
SHIRPA	hindlimb digit number	both	0.0 %	1.00
SHIRPA	hindlimb digit position	females	0.0 %	1.00
SHIRPA	hindlimb digit position	males	0.0 %	1.0
SHIRPA	hindlimb digit position	both	0.0 %	1.0
SHIRPA	hindlimb digit shape	females	0.0 %	1.00
SHIRPA	hindlimb digit shape	males	0.0 %	1.00
SHIRPA	hindlimb digit shape	both	0.0 %	1.0
SHIRPA	hindlimb digit size	females	0.0 %	1.00
SHIRPA	hindlimb digit size	males	0.0 %	1.0
SHIRPA	hindlimb digit size	both	0.0 %	1.0
SHIRPA	hindlimb nail length	females	0.0 %	1.0
SHIRPA	hindlimb nail length	males	0.0 %	1.0
SHIRPA	hindlimb nail length	both	0.0 %	1.00
SHIRPA	hindlimb nail number	females	0.0 %	1.0
SHIRPA	hindlimb nail number	males	1.0 %	1.0
SHIRPA	hindlimb nail number	both	0.0 %	1.00
SHIRPA	hindlimb nail position	females	0.0 %	1.0
SHIRPA	hindlimb nail position	males	0.0 %	1.0
SHIRPA	hindlimb nail position	both	0.0 %	1.0
SHIRPA	hindlimb nail shape	females	0.0 %	1.0
SHIRPA	hindlimb nail shape	males	0.0 %	1.0
SHIRPA	hindlimb nail shape	both	0.0 %	1.0
SHIRPA	hindlimbs footpads	females	0.0 %	1.00
SHIRPA	hindlimbs footpads	males	0.0 %	1.0
SHIRPA	hindlimbs footpads	both	0.0 %	1.0
SHIRPA	hindlimbs position	females	0.0 %	1.0
SHIRPA	hindlimbs position	males	0.0 %	1.0
SHIRPA	hindlimbs position	both	0.0 %	1.0
SHIRPA	hindlimbs shape	females	0.0 %	1.0
SHIRPA	hindlimbs shape	males	0.0 %	1.0
SHIRPA	hindlimbs shape	both	0.0 %	1.0
SHIRPA	hindlimbs size	females	0.0 %	1.0
SHIRPA	hindlimbs size	males	0.0 %	1.0
SHIRPA	hindlimbs size	both	0.0 %	1.0
SHIRPA	hindpaw position	females	0.0 %	1.0
SHIRPA	hindpaw position	males	0.0 %	1.0
SHIRPA	hindpaw position	both	0.0 %	1.0
SHIRPA	hindpaw shape	females	0.0 %	1.00
SHIRPA	hindpaw shape	males	0.0 %	1.0
SHIRPA	hindpaw shape	both	0.0 %	1.0
SHIRPA	hindpaw size	females	0.0 %	1.00
SHIRPA	hindpaw size	males	0.0 %	1.0
SHIRPA	hindpaw size	both	0.0 %	1.0
SHIRPA	limb grasp	females	2.0 %	0.566
SHIRPA	limb grasp	males	6.0 %	1.00
SHIRPA	limb grasp	both	2.0 %	1.0
SHIRPA	lower lip morphology	females	0.0 %	1.00
SHIRPA	lower lip morphology	males	0.0 %	1.0
SHIRPA	lower lip morphology	both	0.0 %	1.0
SHIRPA	lower teeth appearance	females	0.0 %	1.0
SHIRPA	lower teeth appearance	males	0.0 %	1.0
SHIRPA	lower teeth appearance	both	0.0 %	1.0
SHIRPA	mouth morphology	females	0.0 %	1.0
SHIRPA	mouth morphology	males	0.0 %	1.00
SHIRPA	mouth morphology	both	0.0 %	1.00
SHIRPA	salivation	females	0.0 %	1.0
SHIRPA	salivation	males	0.0 %	1.0
SHIRPA	salivation	both	0.0 %	1.0
SHIRPA	skin color back paws	females	0.0 %	1.0
SHIRPA	skin color back paws	males	0.0 %	1.0
SHIRPA	skin color back paws	both	0.0 %	1.0
SHIRPA	skin color ear	females	0.0 %	1.0
SHIRPA	skin color ear	males	0.0 %	1.0
SHIRPA	skin color ear	both	0.0 %	1.0
SHIRPA	skin color front paws	females	0.0 %	1.0
SHIRPA	skin color front paws	males	0.0 %	1.0
SHIRPA	skin color front paws	both	0.0 %	1.0
SHIRPA	skin color snout	females	0.0 %	1.0
SHIRPA	skin color snout	males	0.0 %	1.0
SHIRPA	skin color snout	both	0.0 %	1.0
SHIRPA	skin color tail	females	0.0 %	1.0
SHIRPA	skin color tail	males	0.0 %	1.0
SHIRPA	skin color tail	both	0.0 %	1.0
SHIRPA	skin color whole body	females	0.0 %	1.00
SHIRPA	skin color whole body	males	0.0 %	1.0
SHIRPA	skin color whole body	both	0.0 %	1.0
SHIRPA	skin texture back paw	females	0.0 %	1.0
SHIRPA	skin texture back paw	males	0.0 %	1.0
SHIRPA	skin texture back paw	both	0.0 %	1.0
SHIRPA	skin texture ear	females	0.0 %	1.0
SHIRPA	skin texture ear	males	0.0 %	1.0
SHIRPA	skin texture ear	both	0.0 %	1.0
SHIRPA	skin texture front paws	females	0.0 %	1.0
SHIRPA	skin texture front paws	males	0.0 %	1.0
SHIRPA	skin texture front paws	both	0.0 %	1.0
SHIRPA	skin texture snout	females	0.0 %	1.0
SHIRPA	skin texture snout	males	0.0 %	1.0
SHIRPA	skin texture snout	both	0.0 %	1.0
SHIRPA	skin texture tail	females	0.0 %	1.0
SHIRPA	skin texture tail	males	0.0 %	1.0
SHIRPA	skin texture tail	both	0.0 %	1.0
SHIRPA	skin texture whole body	females	0.0 %	1.0
SHIRPA	skin texture whole body	males	0.0 %	1.0
SHIRPA	skin texture whole body	both	0.0 %	1.00
SHIRPA	snout size	females	0.0 %	1.00
SHIRPA	snout size	males	1.0 %	1.00
SHIRPA	snout size	both	0.0 %	1.0
SHIRPA	startle response	females	0.0 %	1.0
SHIRPA	startle response	males	0.0 %	1.0
SHIRPA	startle response	both	0.0 %	1.0
SHIRPA	tail curvature	females	0.0 %	1.0
SHIRPA	tail curvature	males	0.0 %	1.0
SHIRPA	tail curvature	both	0.0 %	1.0
SHIRPA	tail elevation	females	1.0 %	1.00
SHIRPA	tail elevation	males	2.0 %	1.0
SHIRPA	tail elevation	both	1.0 %	1.0
SHIRPA	tail length	females	0.0 %	1.00
SHIRPA	tail length	males	0.0 %	1.00
SHIRPA	tail length	both	0.0 %	1.0
SHIRPA	tail morphology	females	0.0 %	1.0
SHIRPA	tail morphology	males	0.0 %	1.00
SHIRPA	tail morphology	both	0.0 %	1.00
SHIRPA	tail presence	females	0.0 %	1.0
SHIRPA	tail presence	males	0.0 %	1.0
SHIRPA	tail presence	both	0.0 %	1.0
SHIRPA	tail shape	females	0.0 %	1.00
SHIRPA	tail shape	males	0.0 %	1.0
SHIRPA	tail shape	both	0.0 %	1.0
SHIRPA	tail thickness	females	0.0 %	1.0
SHIRPA	tail thickness	males	0.0 %	1.0
SHIRPA	tail thickness	both	0.0 %	1.0
SHIRPA	teeth presence	females	0.0 %	1.00
SHIRPA	teeth presence	males	0.0 %	1.00
SHIRPA	teeth presence	both	0.0 %	1.0
SHIRPA	transfer arousal	females	1.0 %	1.0
SHIRPA	transfer arousal	males	2.0 %	1.0
SHIRPA	transfer arousal	both	1.0 %	1.0
SHIRPA	tremor	females	0.0 %	1.00
SHIRPA	tremor	males	0.0 %	1.0
SHIRPA	tremor	both	0.0 %	1.0
SHIRPA	trunk curl	females	0.0 %	1.0
SHIRPA	trunk curl	males	0.0 %	1.00
SHIRPA	trunk curl	both	0.0 %	1.0
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	females	0.0 %	1.0
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	males	0.0 %	1.0
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	both	0.0 %	1.00
SHIRPA	upper lip morphology	females	0.0 %	1.0
SHIRPA	upper lip morphology	males	0.0 %	1.0
SHIRPA	upper lip morphology	both	0.0 %	1.0
SHIRPA	upper teeth appearance	females	0.0 %	1.00
SHIRPA	upper teeth appearance	males	0.0 %	1.00
SHIRPA	upper teeth appearance	both	0.0 %	1.0
SHIRPA	vibrissae appearance	females	2.0 %	1.0
SHIRPA	vibrissae appearance	males	1.0 %	1.0
SHIRPA	vibrissae appearance	both	1.0 %	1.0
SHIRPA	vibrissae presence	females	2.0 %	1.0
SHIRPA	vibrissae presence	males	1.0 %	1.00
SHIRPA	vibrissae presence	both	2.0 %	1.00
SHIRPA	vocalization	females	2.0 %	1.0
SHIRPA	vocalization	males	2.0 %	1.0
SHIRPA	vocalization	both	2.0 %	1.0

GENOTYPE CORRELATION PLOT

Correlate Ofcc1^em1(IMPC)J -/- with genotype:

This genotype correlation visualization can include both EAP and LAP measures.