MPD: JaxKOMP-EAP genotype: Arhgap29<sup>em1(IMPC)J</sup> -/+

JaxKOMP-EAP effect sizes: Arhgap29^em1(IMPC)J -/+ Gene Arhgap29

MULTIPLE (NUMERIC) TRAIT PROFILE PLOT — Early Adult Phenotyping study (EAP)

Procedure	JaxKOMP-EAP Trait	Trait Effect	Trait Effect SE	Trait Effect RankZ	Adjusted p-value	Unadjusted p-value
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 6 kHz pip	3.3617	2.3829	0.72791	0.608	0.179
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 12 kHz pip	5.1275	3.0396	1.0544	0.569	0.112
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 18 kHz pip	2.5783	7.1097	0.36665	0.903	0.722
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 24 kHz pip	-1.1867	2.7717	-0.30221	0.878	0.675
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 30 kHz pip	5.6250	4.0834	0.85893	0.573	0.189
body composition	body length	-0.0077908	0.045087	0.094224	0.949	0.864
body composition	body weight (at time of DXA)	-0.082804	0.47664	0.022517	0.944	0.863
body composition	bone area, whole body scan, head excluded	0.011579	0.14714	0.23282	0.982	0.938
body composition	bone mineral content of whole body scan, head excluded	0.000080365	0.011176	0.14109	0.998	0.994
body composition	bone mineral content to body weight ratio	0.000036552	0.00045336	0.20067	0.977	0.936
body composition	bone mineral density of whole body scan, head excluded	-0.000053544	0.00053993	-0.028007	0.977	0.922
body composition	fat tissue mass of whole body scan, head excluded	0.030500	0.26708	0.051903	0.961	0.910
body composition	fat tissue mass to body weight ratio	-0.00048114	0.0095406	0.035504	0.987	0.960
body composition	lean tissue mass of whole body scan, head excluded	0.078903	0.22737	0.012288	0.891	0.730
body composition	lean tissue mass to body weight ratio	0.0045432	0.0084768	0.18755	0.801	0.595
body composition	percent fat, whole body scan, head excluded	-0.093979	0.91736	0.017749	0.965	0.919
body composition	ratio of soft-tissue attenuation coefficients	0.000068906	0.0010368	-0.034213	0.980	0.947
body composition	tissue area	-0.23110	0.15441	-0.59507	0.413	0.143
body composition	total tissue mass, whole body scan, head excluded	0.061380	0.17317	-0.084748	0.858	0.725
clinical blood chemistry	alanine transaminase (plasma ALT)	72.756	50.723	2.3198	0.532	0.163
clinical blood chemistry	albumin (plasma Alb)	-0.39744	0.54807	-0.50066	0.760	0.475
clinical blood chemistry	alkaline phosphatase (plasma ALP)	-1.4349	4.1225	-0.78212	0.868	0.730
clinical blood chemistry	aspartate transaminase (plasma AST)	56.211	52.269	1.6695	0.614	0.292
clinical blood chemistry	aspartate transaminase to alanine transaminase ratio (plasma AST:ALT)	-0.061904	0.49367	-0.20004	0.972	0.901
clinical blood chemistry	blood urea nitrogen (BUN)	-1.1612	1.4925	-0.51734	0.697	0.443
clinical blood chemistry	calcium (plasma Ca)	0.068191	0.090804	0.80687	0.683	0.459
clinical blood chemistry	creatinine (plasma)	-0.014799	0.042171	-0.25715	0.851	0.728
clinical blood chemistry	glucose (plasma GLU, no fast)	-18.024	11.302	-0.39804	0.295	0.122
clinical blood chemistry	HDL cholesterol (plasma HDL)	-4.5748	2.6385	-1.2466	0.332	0.0943
clinical blood chemistry	HDL cholesterol to total cholesterol ratio	-0.0041997	0.0099067	-0.40587	0.889	0.675
clinical blood chemistry	phosphorus (plasma phosphate)	0.55777	0.43675	0.79345	0.493	0.212
clinical blood chemistry	total bilirubin (plasma TBIL)	0.0062235	0.014551	0.42244	0.873	0.672
clinical blood chemistry	total cholesterol (plasma CHOL, no fast)	-5.6857	3.1008	-1.1189	0.301	0.0778
clinical blood chemistry	total protein (plasma TP)	0.19716	0.64458	0.092919	0.890	0.762
clinical blood chemistry	triglyceride (plasma TG, no fast)	-8.5109	8.2130	-0.26044	0.599	0.309
EKG	duration of PQ interval	-0.96499	0.93007	-0.86423	0.867	0.358
EKG	duration of PR interval	-1.5327	1.0626	-1.3307	0.774	0.223
EKG	duration of QRS interval	-0.56862	0.40448	-1.7392	0.885	0.232
EKG	duration of QT interval	-0.63272	0.69508	-0.44551	0.858	0.414
EKG	duration of QTC interval, calculated by dividing QT interval by square root of preceding RR interval	-0.72518	0.74043	-0.68464	0.878	0.383
EKG	duration of RR interval	-0.61082	2.3513	-0.032245	0.934	0.808
EKG	duration of ST interval	-0.036799	0.80897	0.17416	0.987	0.966
EKG	heart rate coefficient of variation (signal intensity)	0.93059	0.85903	0.84392	0.867	0.340
EKG	heart rate variability, mean of differences between sequential beats; beats per min	7.3827	6.3113	0.93677	0.853	0.307
EKG	heart rate, beats per min	6.9001	22.420	0.15081	0.919	0.774
EKG	mean R amplitude, mean amplitude of signal measured from isoelectric line to peak of QRS	-0.063598	0.13199	-0.64379	0.891	0.655
EKG	mean SR amplitude, mean amplitude of signal measured from signal minimum line to peak of QRS	-0.043736	0.18726	-0.34447	0.936	0.827
EKG	number of signals	4.4482	5.9413	0.84105	0.877	0.496
EKG	proportion of number pairs of successive beat-to-beat intervals that exceed 50 ms	-3.6237	3.3849	-0.58999	0.846	0.345
EKG	QT dispersion, measured as inter-lead variability of QT intervals	1.5273	1.7284	0.47463	0.939	0.427
EKG	QTc dispersion, calculated as rate-corrected QT dispersion	3.5522	2.0953	0.92126	0.856	0.165
EKG	root mean square of successive differences of neighboring RR intervals	1.7877	1.3039	0.98146	0.843	0.242
glucose tolerance test	amount glucose injected	-2.7423	1.8848	-0.43475	0.514	0.154
glucose tolerance test	plasma glucose, 0min	12.051	4.0051	0.97696	0.0333	0.00458
glucose tolerance test	plasma glucose, 15min	-6.3026	19.998	-0.075573	0.912	0.754
glucose tolerance test	plasma glucose, 30min	1.7809	20.552	0.18779	0.974	0.931
glucose tolerance test	plasma glucose, 60min	-0.25355	13.075	0.12248	0.991	0.985
glucose tolerance test	plasma glucose, 120min	-1.7910	8.2649	-0.25817	0.934	0.830
grip strength	body weight (at time of grip strength test)	0.11446	0.46647	0.30797	0.892	0.808
grip strength	forelimb and hindlimb grip strength (mean of trials), average	-6.0684	9.0063	-0.20919	0.696	0.505
grip strength	forelimb and hindlimb grip strength (mean of trials), average normalized to bw	-0.33125	0.46571	-0.26897	0.676	0.481
grip strength	forelimb and hindlimb grip strength by trial, trial1	-9.1410	9.7033	-0.39331	0.648	0.353
grip strength	forelimb and hindlimb grip strength by trial, trial2	-12.687	11.524	-0.57131	0.533	0.278
grip strength	forelimb and hindlimb grip strength by trial, trial3	5.4470	10.611	0.56449	0.811	0.611
grip strength	forelimb grip strength (mean of trials), average	-6.2025	4.4107	-0.52240	0.408	0.168
grip strength	forelimb grip strength (mean of trials), average normalized to bw	-0.32828	0.21184	-0.59368	0.372	0.130
grip strength	forelimb grip strength by trial, trial1	-6.2574	6.1451	-0.45529	0.662	0.315
grip strength	forelimb grip strength by trial, trial2	-2.9255	7.1770	-0.098916	0.886	0.686
grip strength	forelimb grip strength by trial, trial3	-6.9956	5.1073	-0.52407	0.492	0.179
heart weight	heart weight, normalized to body weight	-0.065238	0.15048	-0.71012	0.815	0.667
heart weight	heart weight, weight	-2.2962	3.8872	-0.68087	0.733	0.558
hematology	basophil differential (percent of total WBC)	0.032778	0.089298	0.52566	0.921	0.716
hematology	calculated hemoglobin (cHGB)	0.12977	0.22631	0.10624	0.788	0.571
hematology	eosinophil differential (percent of total WBC)	-0.0027211	0.24191	0.071856	0.995	0.991
hematology	hematocrit (HCT)	0.67785	0.68017	0.37636	0.609	0.328
hematology	hemoglobin concentration distribution width (HDW)	0.022784	0.017963	0.63040	0.517	0.215
hematology	large unstained cells (percent of total WBC)	-0.15517	0.14105	-0.98279	0.621	0.281
hematology	lymphocyte differential (percent of total WBC)	-0.43134	1.7036	-0.22886	0.909	0.802
hematology	mean corpuscular hemoglobin (CHr)	-0.0059774	0.053569	-0.020049	0.952	0.912
hematology	mean platelet volume (MPV)	-0.040428	0.14479	-0.45646	0.896	0.782
hematology	mean RBC corpuscular hemoglobin (MCH)	-0.55279	0.21220	-1.2093	0.162	0.0145
hematology	mean RBC corpuscular hemoglobin concentration (MCHC)	-1.1157	0.49126	-1.3264	0.242	0.0310
hematology	mean RBC corpuscular volume (MCV)	-0.055364	0.33606	-0.097192	0.946	0.870
hematology	measured hemoglobin (mHGB)	-0.37304	0.18642	-1.0109	0.275	0.0552
hematology	monocyte differential (percent of total WBC)	-0.20333	0.51843	-0.46904	0.895	0.698
hematology	neutrophil differential (percent of total WBC)	-0.065898	2.4250	-0.020503	0.991	0.979
hematology	platelet count (PLT; units per volume x 10³)	228.73	84.800	2.3131	0.156	0.0117
hematology	RBC corpuscular distribution width (RDW)	0.27360	0.16065	0.95618	0.319	0.0996
hematology	RBC corpuscular hemoglobin concentration mean (CHCM)	-0.067364	0.27429	-0.21755	0.921	0.808
hematology	red blood cell count (RBC; per volume x 10⁶)	0.14263	0.15839	0.30571	0.644	0.376
hematology	reticulocyte count (Retic; units per volume x 10⁹)	-3.0561	13.256	-0.044653	0.946	0.819
hematology	reticulocyte differential (percent of total RBC)	-0.033054	0.15032	0.090662	0.933	0.828
hematology	white blood cell count (WBC; units per volume x 10³)	-0.21022	0.65690	0.034176	0.864	0.751
holeboard	number of hole pokes by individual hole number, 20 min test, 1	-1.2563	1.1818	-1.2031	0.739	0.296
holeboard	number of hole pokes by individual hole number, 20 min test, 2	-0.083924	0.48069	-0.0025320	0.980	0.863
holeboard	number of hole pokes by individual hole number, 20 min test, 3	-0.73449	0.49100	-1.1689	0.661	0.145
holeboard	number of hole pokes by individual hole number, 20 min test, 4	0.092317	0.85315	0.17903	0.979	0.915
holeboard	number of hole pokes by individual hole number, 20 min test, 5	-1.0848	0.41119	-1.6272	0.336	0.0129
holeboard	number of hole pokes by individual hole number, 20 min test, 6	-0.46945	0.29237	-1.3274	0.713	0.118
holeboard	number of hole pokes by individual hole number, 20 min test, 7	-0.23161	0.33295	-0.66129	0.913	0.492
holeboard	number of hole pokes by individual hole number, 20 min test, 8	-1.1829	0.50601	-1.8030	0.460	0.0260
holeboard	number of hole pokes by individual hole number, 20 min test, 9	-0.045975	0.44756	0.0033782	0.990	0.919
holeboard	number of hole pokes by individual hole number, 20 min test, 10	0.048811	0.31375	0.19748	0.971	0.877
holeboard	number of hole pokes by individual hole number, 20 min test, 11	-0.47490	0.29914	-1.2603	0.700	0.123
holeboard	number of hole pokes by individual hole number, 20 min test, 12	-0.96406	0.73106	-1.4136	0.642	0.197
holeboard	number of hole pokes by individual hole number, 20 min test, 13	-0.40301	1.1800	-0.30138	0.932	0.735
holeboard	number of hole pokes by individual hole number, 20 min test, 14	-1.0672	0.59263	-1.6600	0.491	0.0818
holeboard	number of hole pokes by individual hole number, 20 min test, 15	-0.16250	0.57468	-0.13876	0.915	0.779
holeboard	number of hole pokes by individual hole number, 20 min test, 16	-0.26764	0.85755	-0.20899	0.933	0.757
holeboard	total number of hole pokes, 20 min test	-6.9853	5.7896	-0.90892	0.529	0.237
light / dark	fecal boli count, 20 min test	-0.58333	0.93055	-0.61458	0.841	0.534
light / dark	latency to enter dark zone, 20 min test	17.296	52.466	0.24025	0.934	0.743
light / dark	number of transitions between light and dark zones, 20 min test	8.2594	10.671	0.85870	0.720	0.443
light / dark	percentage of total time in dark zone, 20 min test	5.6880	4.8378	1.1926	0.612	0.247
light / dark	percentage of total time in light zone, 20 min test	-5.6880	4.8378	-1.1954	0.612	0.247
light / dark	time mobile in dark zone, 20 min test	12.892	15.614	0.65510	0.701	0.414
light / dark	time mobile in light zone, 20 min test	-4.7592	13.495	-0.59107	0.872	0.726
light / dark	time spent in dark zone, 20 min test	34.600	52.009	0.75389	0.832	0.510
light / dark	time spent in light zone, 20 min test	-34.600	52.009	-0.75389	0.832	0.510
open field	average speed in center of arena, 20 min test	0.39621	0.52939	0.60649	0.763	0.458
open field	average speed in periphery of arena, 20 min test	0.33665	0.18729	0.76271	0.223	0.0796
open field	distance traveled habituation ratio, 20 min test	14.518	7.7729	1.1778	0.326	0.0690
open field	distance traveled in center of arena, 20 min test	168.03	82.514	0.70128	0.190	0.0482
open field	distance traveled in periphery of arena, 20 min test	274.05	196.20	0.64735	0.388	0.170
open field	distance traveled slope, 20 min test	15.366	7.2053	1.3376	0.245	0.0390
open field	distance traveled, 20 min test, 1st 5min	43.612	89.586	0.022155	0.828	0.629
open field	distance traveled, 20 min test, 2nd 5min	103.41	64.198	0.62924	0.312	0.115
open field	distance traveled, 20 min test, 3rd 5min	166.40	64.173	1.2746	0.0814	0.0131
open field	distance traveled, 20 min test, 4th 5min	154.57	57.199	1.1592	0.0682	0.00997
open field	number of clockwise revolution episodes, 20 min test	0.82126	1.0059	0.067216	0.754	0.419
open field	number of counter-clockwise revolution episodes, 20 min test	3.8416	1.1795	1.4785	0.0466	0.00230
open field	number of fecal boli, 20 min test	-0.85000	0.77601	-0.41211	0.617	0.280
open field	number of rears in 5 min bins, 20 min test, 1st 5min	-3.9375	1.8626	-1.3020	0.193	0.0406
open field	number of rears in 5 min bins, 20 min test, 2nd 5min	2.7833	2.6054	0.36580	0.580	0.292
open field	number of rears in 5 min bins, 20 min test, 3rd 5min	0.70104	2.4906	-0.15706	0.893	0.780
open field	number of rears in 5 min bins, 20 min test, 4th 5min	-0.15463	2.6713	-0.39031	0.978	0.954
open field	percentage of total time in center of arena, 20 min test	2.2513	2.0848	0.31458	0.603	0.287
open field	percentage of total time in center of arena, slope, 20 min test	2.0047	1.2286	1.2134	0.568	0.110
open field	percentage of total time in center, habituation ratio, 20 min test	1.6473	1.2878	1.0005	0.686	0.208
open field	percentage of total time in corners of arena, 20 min test	-3.5407	3.5502	-0.32306	0.628	0.324
open field	percentage of total time in corners, habituation ratio, 20 min test	-1.7945	2.0871	-1.1131	0.843	0.395
open field	percentage of total time in corners, slope, 20 min test	-2.3209	1.9975	-1.3885	0.741	0.252
open field	permanence time in center of arena, 20 min test	27.012	25.017	0.31458	0.604	0.287
open field	permanence time in corners of arena, 20 min test	-42.486	42.604	-0.32306	0.628	0.324
open field	permanence time in periphery of arena, 20 min test	-26.989	25.021	-0.31458	0.604	0.287
open field	total distance traveled, 20 min test	446.87	240.43	0.76451	0.208	0.0703
open field	total number of rears, 20 min test	-0.94054	7.4822	-0.40630	0.955	0.901
open field	whole arena average speed, 20 min test	0.37154	0.20043	0.76451	0.209	0.0710
open field	whole arena resting time, 20 min test	-51.385	23.223	-0.83475	0.120	0.0326
open field	whole arena time spent mobile, 20 min test	51.320	23.207	1.0551	0.121	0.0326
open field	whole arena time spent vertical, 20 min test	-1.5625	7.3904	-0.23923	0.933	0.834
SHIRPA	locomotor activity (number of squares in the arena the mouse moves into with all four paws in first 30 s of test)	1.7390	1.5499	0.92026	0.587	0.269
startle / PPI	average baseline movement during background noise	-0.75159	1.1524	-0.50314	0.892	0.518
startle / PPI	average of each corrected maximum percent pre-pulse inhibition value	-0.0016847	0.071138	-0.11726	0.994	0.981
startle / PPI	average of each corrected percent pre-pulse inhibition value	0.00068658	0.067839	-0.072302	0.997	0.992
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-6.6566	9.4442	-0.68375	0.895	0.485
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-3.4216	7.5471	-0.39462	0.872	0.653
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	0.72493	6.3475	-0.024522	0.968	0.910
startle / PPI	average startle response to full pulse (120 dB)	-56.816	22.189	-0.80582	0.0829	0.0142
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-45.142	18.855	-0.64186	0.101	0.0213
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-28.716	21.950	-0.40981	0.411	0.198
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-23.064	19.707	-0.36600	0.467	0.249
startle / PPI	average startle response to pre-pulse, 74dB sound pressure level	-0.50191	1.1763	-0.30815	0.937	0.672
startle / PPI	average startle response to pre-pulse, 78dB sound pressure level	0.79541	0.91886	0.52231	0.854	0.392
startle / PPI	average startle response to pre-pulse, 82dB sound pressure level	1.1868	1.0522	0.37952	0.694	0.266
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-0.067507	0.10184	-0.60443	0.913	0.511
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	0.0073139	0.086132	-0.024550	0.981	0.933
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	0.062147	0.075293	0.32676	0.675	0.414
startle / PPI	corrected average startle response to full pulse (120 dB) minus average baseline movement during background noise	-56.413	22.292	-0.79232	0.0864	0.0153
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 74dB sound pressure level	-44.666	18.967	-0.63499	0.108	0.0234
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 78dB sound pressure level	-29.595	22.059	-0.41744	0.395	0.187
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 82dB sound pressure level	-24.251	19.728	-0.38102	0.439	0.226
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-0.080642	0.11591	-0.69798	0.916	0.491
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	0.016105	0.089071	0.022433	0.942	0.857
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	0.059103	0.079140	0.25219	0.697	0.459
startle / PPI	corrected maximum startle response to full pulse (120 dB) minus maximum baseline movement during background noise	-212.72	87.745	-0.85730	0.101	0.0198
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 74dB sound pressure level	-174.32	72.927	-0.70695	0.0981	0.0215
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 78dB sound pressure level	-111.34	87.249	-0.41897	0.425	0.209
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 82dB sound pressure level	-84.825	77.675	-0.35553	0.494	0.281
startle / PPI	maximum baseline movement during background noise	-0.71181	2.7788	-0.11585	0.960	0.799
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-7.4317	11.134	-0.69085	0.919	0.508
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-2.1388	8.0975	-0.25856	0.918	0.793
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	1.2236	7.0162	-0.037139	0.943	0.862
startle / PPI	maximum startle response to full pulse (120 dB)	-212.89	87.596	-0.85528	0.100	0.0195
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-175.30	72.882	-0.71416	0.0969	0.0208
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-108.58	87.023	-0.42203	0.436	0.219
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-80.194	77.534	-0.33916	0.528	0.307
startle / PPI	maximum startle response to pre-pulse, 74dB sound pressure level	-1.1217	2.5493	-0.25566	0.925	0.662
startle / PPI	maximum startle response to pre-pulse, 78dB sound pressure level	2.5032	2.0425	0.69263	0.717	0.227
startle / PPI	maximum startle response to pre-pulse, 82dB sound pressure level	4.6313	2.7103	0.62645	0.464	0.0951

MULTIPLE (CATEGORICAL) TRAIT PROFILE PLOT — Early Adult Phenotyping study (EAP)

Procedure	JaxKOMP-EAP Trait	Sex	Trait Effect	P-value
eye morphology	anterior chamber depth	females	1.0 %	1.0
eye morphology	anterior chamber depth	both	1.0 %	1.0
eye morphology	bulging eye	females	1.0 %	1.0
eye morphology	bulging eye	both	1.0 %	1.00
eye morphology	cornea	females	4.0 %	1.0
eye morphology	cornea	both	3.0 %	1.00
eye morphology	cornea opacity	females	5.0 %	1.0
eye morphology	cornea opacity	both	3.0 %	1.0
eye morphology	cornea vascularization	females	3.0 %	1.0
eye morphology	cornea vascularization	both	2.0 %	1.0
eye morphology	corneal deposits	females	2.0 %	1.0
eye morphology	corneal deposits	both	1.0 %	1.00
eye morphology	corneal mineralization	females	2.0 %	1.0
eye morphology	corneal mineralization	both	1.0 %	1.00
eye morphology	corneal scleralization	females	3.0 %	1.0
eye morphology	corneal scleralization	both	2.0 %	1.0
eye morphology	corneal ulcer	females	1.0 %	1.0
eye morphology	corneal ulcer	both	1.0 %	1.00
eye morphology	eye closure	females	1.0 %	1.0
eye morphology	eye closure	both	1.0 %	1.00
eye morphology	eye hemorrhage or blood presence	females	2.0 %	1.0
eye morphology	eye hemorrhage or blood presence	both	1.0 %	1.0
eye morphology	eyelid morphology	females	1.0 %	1.00
eye morphology	eyelid morphology	both	1.0 %	1.00
eye morphology	eyes (present, absent)	females	1.0 %	1.00
eye morphology	eyes (present, absent)	both	0.0 %	1.00
eye morphology	fusion between cornea and lens	females	4.0 %	1.0
eye morphology	fusion between cornea and lens	both	3.0 %	1.0
eye morphology	iris pigmentation	females	2.0 %	1.0
eye morphology	iris pigmentation	both	2.0 %	1.0
eye morphology	iris transillumination	females	2.0 %	1.0
eye morphology	iris transillumination	both	1.0 %	1.00
eye morphology	irispupil	females	4.0 %	1.0
eye morphology	irispupil	both	3.0 %	1.0
eye morphology	lacrimation	females	3.0 %	1.0
eye morphology	lacrimation	both	3.0 %	1.00
eye morphology	lens	females	10.0 %	1.0
eye morphology	lens	both	9.0 %	1.00
eye morphology	lens opacity	females	9.0 %	1.0
eye morphology	lens opacity	both	7.0 %	1.00
eye morphology	narrow eye opening	females	2.0 %	1.00
eye morphology	narrow eye opening	both	1.0 %	1.00
eye morphology	optic disc	females	4.0 %	1.0
eye morphology	optic disc	both	3.0 %	1.00
eye morphology	persistence of hyaloid vascular system	females	14.0 %	1.0
eye morphology	persistence of hyaloid vascular system	both	9.0 %	1.00
eye morphology	pupil dilation	females	2.0 %	1.0
eye morphology	pupil dilation	both	2.0 %	1.00
eye morphology	pupil light response	females	2.0 %	1.0
eye morphology	pupil light response	both	2.0 %	1.0
eye morphology	pupil position	females	4.0 %	1.0
eye morphology	pupil position	both	4.0 %	1.0
eye morphology	pupil shape	females	3.0 %	1.0
eye morphology	pupil shape	both	3.0 %	1.0
eye morphology	retina	females	10.0 %	1.00
eye morphology	retina	both	13.0 %	1.00
eye morphology	retinal blood vessels	females	4.0 %	1.0
eye morphology	retinal blood vessels	both	3.0 %	1.00
eye morphology	retinal blood vessels pattern	females	5.0 %	1.0
eye morphology	retinal blood vessels pattern	both	4.0 %	1.00
eye morphology	retinal blood vessels structure	females	4.0 %	1.0
eye morphology	retinal blood vessels structure	both	3.0 %	1.0
eye morphology	retinal pigmentation	females	12.0 %	1.00
eye morphology	retinal pigmentation	both	13.0 %	1.00
eye morphology	retinal structure	females	4.0 %	1.0
eye morphology	retinal structure	both	3.0 %	1.00
eye morphology	synechia	females	4.0 %	1.0
eye morphology	synechia	both	3.0 %	1.00
eye morphology	vitreous	females	4.0 %	1.0
eye morphology	vitreous	both	3.0 %	1.0
SHIRPA	activity body position	females	1.0 %	1.0
SHIRPA	activity body position	males	2.0 %	1.0
SHIRPA	activity body position	both	1.0 %	1.00
SHIRPA	aggression	females	12.0 %	0.0404
SHIRPA	aggression	males	1.0 %	1.0
SHIRPA	aggression	both	6.0 %	0.0878
SHIRPA	body length	females	0.0 %	1.0
SHIRPA	body length	males	0.0 %	1.00
SHIRPA	body length	both	0.0 %	1.00
SHIRPA	body position	females	0.0 %	1.0
SHIRPA	body position	males	1.0 %	1.0
SHIRPA	body position	both	0.0 %	1.0
SHIRPA	body thickness	females	1.0 %	1.0
SHIRPA	body thickness	males	0.0 %	1.0
SHIRPA	body thickness	both	0.0 %	1.0
SHIRPA	coat color abdomen	females	9.0 %	0.250
SHIRPA	coat color abdomen	males	4.0 %	1.0
SHIRPA	coat color abdomen	both	3.0 %	0.440
SHIRPA	coat color back	females	0.0 %	1.0
SHIRPA	coat color back	males	0.0 %	1.00
SHIRPA	coat color back	both	0.0 %	1.00
SHIRPA	coat color head	females	0.0 %	1.0
SHIRPA	coat color head	males	0.0 %	1.00
SHIRPA	coat color head	both	0.0 %	1.0
SHIRPA	coat color pattern abdomen	females	1.0 %	1.0
SHIRPA	coat color pattern abdomen	males	1.0 %	1.0
SHIRPA	coat color pattern abdomen	both	1.0 %	1.0
SHIRPA	coat color pattern back	females	0.0 %	1.0
SHIRPA	coat color pattern back	males	0.0 %	1.00
SHIRPA	coat color pattern back	both	0.0 %	1.0
SHIRPA	coat color pattern head	females	0.0 %	1.0
SHIRPA	coat color pattern head	males	0.0 %	1.0
SHIRPA	coat color pattern head	both	0.0 %	1.00
SHIRPA	coat hair abdomen texture appearance	females	2.0 %	1.0
SHIRPA	coat hair abdomen texture appearance	males	2.0 %	1.0
SHIRPA	coat hair abdomen texture appearance	both	2.0 %	1.0
SHIRPA	coat hair back texture appearance	females	0.0 %	1.0
SHIRPA	coat hair back texture appearance	males	0.0 %	1.0
SHIRPA	coat hair back texture appearance	both	0.0 %	1.0
SHIRPA	coat hair distribution abdomen	females	0.0 %	1.0
SHIRPA	coat hair distribution abdomen	males	1.0 %	1.00
SHIRPA	coat hair distribution abdomen	both	1.0 %	1.00
SHIRPA	coat hair distribution back	females	0.0 %	1.0
SHIRPA	coat hair distribution back	males	0.0 %	1.0
SHIRPA	coat hair distribution back	both	0.0 %	1.0
SHIRPA	coat hair distribution head	females	1.0 %	1.00
SHIRPA	coat hair distribution head	males	1.0 %	1.0
SHIRPA	coat hair distribution head	both	1.0 %	1.0
SHIRPA	coat hair head texture appearance	females	0.0 %	1.00
SHIRPA	coat hair head texture appearance	males	0.0 %	1.0
SHIRPA	coat hair head texture appearance	both	0.0 %	1.0
SHIRPA	contact righting	females	5.0 %	1.0
SHIRPA	contact righting	males	5.0 %	1.00
SHIRPA	contact righting	both	5.0 %	1.00
SHIRPA	ear morphology	females	0.0 %	1.0
SHIRPA	ear morphology	males	0.0 %	1.0
SHIRPA	ear morphology	both	0.0 %	1.0
SHIRPA	fat distribution	females	0.0 %	1.0
SHIRPA	fat distribution	males	0.0 %	1.0
SHIRPA	fat distribution	both	0.0 %	1.00
SHIRPA	forelimb digit number	females	0.0 %	1.00
SHIRPA	forelimb digit number	males	0.0 %	1.0
SHIRPA	forelimb digit number	both	0.0 %	1.00
SHIRPA	forelimb digit position	females	0.0 %	1.0
SHIRPA	forelimb digit position	males	0.0 %	1.0
SHIRPA	forelimb digit position	both	0.0 %	1.0
SHIRPA	forelimb digit shape	females	0.0 %	1.0
SHIRPA	forelimb digit shape	males	0.0 %	1.0
SHIRPA	forelimb digit shape	both	0.0 %	1.0
SHIRPA	forelimb digit size	females	0.0 %	1.0
SHIRPA	forelimb digit size	males	0.0 %	1.0
SHIRPA	forelimb digit size	both	0.0 %	1.0
SHIRPA	forelimb footpads	females	0.0 %	1.0
SHIRPA	forelimb footpads	males	0.0 %	1.0
SHIRPA	forelimb footpads	both	0.0 %	1.0
SHIRPA	forelimb nail length	females	0.0 %	1.0
SHIRPA	forelimb nail length	males	0.0 %	1.0
SHIRPA	forelimb nail length	both	0.0 %	1.0
SHIRPA	forelimb nail number	females	0.0 %	1.0
SHIRPA	forelimb nail number	males	0.0 %	1.0
SHIRPA	forelimb nail number	both	0.0 %	1.0
SHIRPA	forelimb nail position	females	0.0 %	1.0
SHIRPA	forelimb nail position	males	0.0 %	1.0
SHIRPA	forelimb nail position	both	0.0 %	1.0
SHIRPA	forelimb nail shape	females	0.0 %	1.0
SHIRPA	forelimb nail shape	males	0.0 %	1.0
SHIRPA	forelimb nail shape	both	0.0 %	1.0
SHIRPA	forelimbs position	females	0.0 %	1.0
SHIRPA	forelimbs position	males	0.0 %	1.0
SHIRPA	forelimbs position	both	0.0 %	1.0
SHIRPA	forelimbs shape	females	0.0 %	1.0
SHIRPA	forelimbs shape	males	0.0 %	1.0
SHIRPA	forelimbs shape	both	0.0 %	1.0
SHIRPA	forelimbs size	females	0.0 %	1.0
SHIRPA	forelimbs size	males	0.0 %	1.0
SHIRPA	forelimbs size	both	0.0 %	1.0
SHIRPA	forepaw position	females	0.0 %	1.0
SHIRPA	forepaw position	males	0.0 %	1.0
SHIRPA	forepaw position	both	0.0 %	1.0
SHIRPA	forepaw shape	females	0.0 %	1.0
SHIRPA	forepaw shape	males	0.0 %	1.0
SHIRPA	forepaw shape	both	0.0 %	1.0
SHIRPA	forepaw size	females	0.0 %	1.0
SHIRPA	forepaw size	males	0.0 %	1.0
SHIRPA	forepaw size	both	0.0 %	1.0
SHIRPA	gait (fluidity)	females	0.0 %	1.0
SHIRPA	gait (fluidity)	males	0.0 %	1.00
SHIRPA	gait (fluidity)	both	0.0 %	1.00
SHIRPA	genitalia morphology	females	0.0 %	1.00
SHIRPA	genitalia morphology	males	0.0 %	1.0
SHIRPA	genitalia morphology	both	0.0 %	1.00
SHIRPA	genitalia presence	females	0.0 %	1.0
SHIRPA	genitalia presence	males	0.0 %	1.0
SHIRPA	genitalia presence	both	0.0 %	1.0
SHIRPA	genitalia size	females	0.0 %	1.0
SHIRPA	genitalia size	males	0.0 %	1.0
SHIRPA	genitalia size	both	0.0 %	1.0
SHIRPA	head bobbing	females	0.0 %	1.0
SHIRPA	head bobbing	males	0.0 %	1.0
SHIRPA	head bobbing	both	0.0 %	1.0
SHIRPA	head morphology	females	0.0 %	1.0
SHIRPA	head morphology	males	0.0 %	1.00
SHIRPA	head morphology	both	0.0 %	1.0
SHIRPA	head size	females	0.0 %	1.0
SHIRPA	head size	males	0.0 %	1.0
SHIRPA	head size	both	0.0 %	1.00
SHIRPA	hindlimb digit number	females	1.0 %	1.00
SHIRPA	hindlimb digit number	males	0.0 %	1.0
SHIRPA	hindlimb digit number	both	0.0 %	1.00
SHIRPA	hindlimb digit position	females	0.0 %	1.0
SHIRPA	hindlimb digit position	males	0.0 %	1.0
SHIRPA	hindlimb digit position	both	0.0 %	1.0
SHIRPA	hindlimb digit shape	females	0.0 %	1.0
SHIRPA	hindlimb digit shape	males	0.0 %	1.0
SHIRPA	hindlimb digit shape	both	0.0 %	1.0
SHIRPA	hindlimb digit size	females	0.0 %	1.00
SHIRPA	hindlimb digit size	males	0.0 %	1.0
SHIRPA	hindlimb digit size	both	0.0 %	1.00
SHIRPA	hindlimb nail length	females	0.0 %	1.0
SHIRPA	hindlimb nail length	males	0.0 %	1.0
SHIRPA	hindlimb nail length	both	0.0 %	1.00
SHIRPA	hindlimb nail number	females	0.0 %	1.0
SHIRPA	hindlimb nail number	males	1.0 %	1.0
SHIRPA	hindlimb nail number	both	0.0 %	1.00
SHIRPA	hindlimb nail position	females	0.0 %	1.0
SHIRPA	hindlimb nail position	males	0.0 %	1.0
SHIRPA	hindlimb nail position	both	0.0 %	1.0
SHIRPA	hindlimb nail shape	females	0.0 %	1.0
SHIRPA	hindlimb nail shape	males	0.0 %	1.0
SHIRPA	hindlimb nail shape	both	0.0 %	1.0
SHIRPA	hindlimbs footpads	females	0.0 %	1.0
SHIRPA	hindlimbs footpads	males	0.0 %	1.0
SHIRPA	hindlimbs footpads	both	0.0 %	1.0
SHIRPA	hindlimbs position	females	0.0 %	1.0
SHIRPA	hindlimbs position	males	0.0 %	1.0
SHIRPA	hindlimbs position	both	0.0 %	1.0
SHIRPA	hindlimbs shape	females	0.0 %	1.0
SHIRPA	hindlimbs shape	males	0.0 %	1.0
SHIRPA	hindlimbs shape	both	0.0 %	1.0
SHIRPA	hindlimbs size	females	0.0 %	1.0
SHIRPA	hindlimbs size	males	0.0 %	1.0
SHIRPA	hindlimbs size	both	0.0 %	1.0
SHIRPA	hindpaw position	females	0.0 %	1.0
SHIRPA	hindpaw position	males	0.0 %	1.0
SHIRPA	hindpaw position	both	0.0 %	1.0
SHIRPA	hindpaw shape	females	0.0 %	1.0
SHIRPA	hindpaw shape	males	0.0 %	1.0
SHIRPA	hindpaw shape	both	0.0 %	1.0
SHIRPA	hindpaw size	females	0.0 %	1.0
SHIRPA	hindpaw size	males	0.0 %	1.0
SHIRPA	hindpaw size	both	0.0 %	1.0
SHIRPA	limb grasp	females	9.0 %	1.00
SHIRPA	limb grasp	males	19.0 %	0.0730
SHIRPA	limb grasp	both	5.0 %	0.327
SHIRPA	lower lip morphology	females	0.0 %	1.0
SHIRPA	lower lip morphology	males	0.0 %	1.0
SHIRPA	lower lip morphology	both	0.0 %	1.0
SHIRPA	lower teeth appearance	females	0.0 %	1.0
SHIRPA	lower teeth appearance	males	0.0 %	1.00
SHIRPA	lower teeth appearance	both	0.0 %	1.00
SHIRPA	mouth morphology	females	0.0 %	1.0
SHIRPA	mouth morphology	males	0.0 %	1.00
SHIRPA	mouth morphology	both	0.0 %	1.00
SHIRPA	salivation	females	0.0 %	1.0
SHIRPA	salivation	males	0.0 %	1.0
SHIRPA	salivation	both	0.0 %	1.0
SHIRPA	skin color back paws	females	0.0 %	1.0
SHIRPA	skin color back paws	males	0.0 %	1.0
SHIRPA	skin color back paws	both	0.0 %	1.0
SHIRPA	skin color ear	females	0.0 %	1.0
SHIRPA	skin color ear	males	0.0 %	1.0
SHIRPA	skin color ear	both	0.0 %	1.0
SHIRPA	skin color front paws	females	0.0 %	1.0
SHIRPA	skin color front paws	males	0.0 %	1.0
SHIRPA	skin color front paws	both	0.0 %	1.0
SHIRPA	skin color snout	females	0.0 %	1.0
SHIRPA	skin color snout	males	0.0 %	1.0
SHIRPA	skin color snout	both	0.0 %	1.0
SHIRPA	skin color tail	females	0.0 %	1.0
SHIRPA	skin color tail	males	0.0 %	1.0
SHIRPA	skin color tail	both	0.0 %	1.0
SHIRPA	skin color whole body	females	0.0 %	1.0
SHIRPA	skin color whole body	males	0.0 %	1.0
SHIRPA	skin color whole body	both	0.0 %	1.0
SHIRPA	skin texture back paw	females	0.0 %	1.0
SHIRPA	skin texture back paw	males	0.0 %	1.0
SHIRPA	skin texture back paw	both	0.0 %	1.0
SHIRPA	skin texture ear	females	0.0 %	1.0
SHIRPA	skin texture ear	males	0.0 %	1.0
SHIRPA	skin texture ear	both	0.0 %	1.0
SHIRPA	skin texture front paws	females	0.0 %	1.0
SHIRPA	skin texture front paws	males	0.0 %	1.0
SHIRPA	skin texture front paws	both	0.0 %	1.0
SHIRPA	skin texture snout	females	0.0 %	1.0
SHIRPA	skin texture snout	males	0.0 %	1.0
SHIRPA	skin texture snout	both	0.0 %	1.0
SHIRPA	skin texture tail	females	0.0 %	1.0
SHIRPA	skin texture tail	males	0.0 %	1.0
SHIRPA	skin texture tail	both	0.0 %	1.0
SHIRPA	skin texture whole body	females	0.0 %	1.0
SHIRPA	skin texture whole body	males	0.0 %	1.00
SHIRPA	skin texture whole body	both	0.0 %	1.00
SHIRPA	snout size	females	0.0 %	1.0
SHIRPA	snout size	males	1.0 %	1.0
SHIRPA	snout size	both	0.0 %	1.0
SHIRPA	startle response	females	0.0 %	1.00
SHIRPA	startle response	males	0.0 %	1.00
SHIRPA	startle response	both	0.0 %	1.00
SHIRPA	tail curvature	females	0.0 %	1.00
SHIRPA	tail curvature	males	0.0 %	1.0
SHIRPA	tail curvature	both	0.0 %	1.0
SHIRPA	tail elevation	females	1.0 %	1.00
SHIRPA	tail elevation	males	2.0 %	1.0
SHIRPA	tail elevation	both	1.0 %	1.0
SHIRPA	tail length	females	0.0 %	1.0
SHIRPA	tail length	males	0.0 %	1.0
SHIRPA	tail length	both	0.0 %	1.00
SHIRPA	tail morphology	females	0.0 %	1.00
SHIRPA	tail morphology	males	0.0 %	1.0
SHIRPA	tail morphology	both	0.0 %	1.00
SHIRPA	tail presence	females	0.0 %	1.0
SHIRPA	tail presence	males	0.0 %	1.0
SHIRPA	tail presence	both	0.0 %	1.0
SHIRPA	tail shape	females	0.0 %	1.0
SHIRPA	tail shape	males	0.0 %	1.0
SHIRPA	tail shape	both	0.0 %	1.00
SHIRPA	tail thickness	females	0.0 %	1.0
SHIRPA	tail thickness	males	0.0 %	1.0
SHIRPA	tail thickness	both	0.0 %	1.0
SHIRPA	teeth presence	females	0.0 %	1.0
SHIRPA	teeth presence	males	0.0 %	1.00
SHIRPA	teeth presence	both	0.0 %	1.00
SHIRPA	transfer arousal	females	1.0 %	1.0
SHIRPA	transfer arousal	males	2.0 %	1.00
SHIRPA	transfer arousal	both	1.0 %	1.0
SHIRPA	tremor	females	0.0 %	1.0
SHIRPA	tremor	males	0.0 %	1.0
SHIRPA	tremor	both	0.0 %	1.00
SHIRPA	trunk curl	females	0.0 %	1.00
SHIRPA	trunk curl	males	0.0 %	1.0
SHIRPA	trunk curl	both	0.0 %	1.0
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	females	0.0 %	1.0
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	males	0.0 %	1.0
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	both	0.0 %	1.00
SHIRPA	upper lip morphology	females	0.0 %	1.0
SHIRPA	upper lip morphology	males	0.0 %	1.0
SHIRPA	upper lip morphology	both	0.0 %	1.0
SHIRPA	upper teeth appearance	females	0.0 %	1.0
SHIRPA	upper teeth appearance	males	0.0 %	1.0
SHIRPA	upper teeth appearance	both	0.0 %	1.00
SHIRPA	vibrissae appearance	females	2.0 %	1.0
SHIRPA	vibrissae appearance	males	1.0 %	1.0
SHIRPA	vibrissae appearance	both	1.0 %	1.0
SHIRPA	vibrissae presence	females	2.0 %	1.00
SHIRPA	vibrissae presence	males	1.0 %	1.0
SHIRPA	vibrissae presence	both	2.0 %	1.0
SHIRPA	vocalization	females	2.0 %	1.00
SHIRPA	vocalization	males	2.0 %	1.0
SHIRPA	vocalization	both	2.0 %	1.00

GENOTYPE CORRELATION PLOT

Correlate Arhgap29^em1(IMPC)J -/+ with genotype: