MPD: JaxKOMP-EAP genotype: Dnajc30<sup>tm1.1(KOMP)Vlcg</sup>/2J -/-

JaxKOMP-EAP effect sizes: Dnajc30^{tm1.1(KOMP)Vlcg}/2J -/- Gene Dnajc30

MULTIPLE (NUMERIC) TRAIT PROFILE PLOT — Early Adult Phenotyping study (EAP)

In this plot, data points are the computed genotype effect size vs. C57BL/6NJ controls, for all measured numeric phenotypes in JaxKOMP-EAP

Dimensions Width: × Height: px

Plot Options Group by Procedure Standard Error Show Effect Sizes RankZ

Significance Threshold p-Value Threshold Adjusted Unadjusted

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Procedure	JaxKOMP-EAP Trait	Trait Effect	Trait Effect SE	Trait Effect RankZ	Adjusted p-value	Unadjusted p-value

ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 12 kHz pip	-2.7674	2.9311	-0.62247	0.810	0.399
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 18 kHz pip	-1.4794	1.4105	-0.51060	0.713	0.353
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 24 kHz pip	-4.3851	7.3551	-0.81034	0.835	0.583
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 30 kHz pip	-3.3036	8.7481	-0.54120	0.887	0.725
body composition	body length	-0.047864	0.038433	-0.35553	0.515	0.218
body composition	body weight (at time of DXA)	-0.24738	0.56130	-0.11007	0.821	0.661
body composition	bone area, whole body scan, head excluded	-0.26360	0.13428	-0.84982	0.227	0.0545
body composition	bone mineral content of whole body scan, head excluded	-0.031272	0.010066	-1.4083	0.0392	0.00295
body composition	bone mineral content to body weight ratio	-0.0010680	0.00039664	-1.1256	0.0755	0.00929
body composition	bone mineral density of whole body scan, head excluded	-0.0019976	0.00045549	-1.8135	0.00330	0.0000504
body composition	fat tissue mass of whole body scan, head excluded	0.33829	0.25676	0.55249	0.432	0.193
body composition	fat tissue mass to body weight ratio	0.014887	0.0092934	0.71446	0.304	0.115
body composition	lean tissue mass of whole body scan, head excluded	-0.43103	0.24032	-1.0281	0.321	0.0782
body composition	lean tissue mass to body weight ratio	-0.0030779	0.0080030	-0.22804	0.858	0.702
body composition	percent fat, whole body scan, head excluded	1.2806	0.88814	0.67620	0.374	0.155
body composition	ratio of soft-tissue attenuation coefficients	-0.0013783	0.00099053	-0.65911	0.395	0.169
body composition	tissue area	-0.10379	0.12446	-0.17862	0.707	0.408
body composition	total tissue mass, whole body scan, head excluded	-0.14936	0.16262	-0.57812	0.613	0.362
clinical blood chemistry	alanine transaminase (plasma ALT)	-18.549	16.978	-1.3699	0.649	0.281
clinical blood chemistry	albumin (plasma Alb)	0.87907	0.58940	1.2940	0.458	0.144
clinical blood chemistry	alkaline phosphatase (plasma ALP)	8.2828	4.0182	0.87397	0.187	0.0464
clinical blood chemistry	aspartate transaminase (plasma AST)	-48.455	30.890	-1.7825	0.432	0.125
clinical blood chemistry	aspartate transaminase to alanine transaminase ratio (plasma AST:ALT)	-0.42692	0.27858	-1.2395	0.524	0.134
clinical blood chemistry	blood urea nitrogen (BUN)	-2.5824	1.4250	-1.0422	0.271	0.0781
clinical blood chemistry	calcium (plasma Ca)	0.41720	0.10973	2.2981	0.0101	0.000506
clinical blood chemistry	creatinine (plasma)	-0.058788	0.029116	-1.1678	0.204	0.0510
clinical blood chemistry	glucose (plasma GLU, no fast)	-13.283	12.386	-0.23128	0.495	0.290
clinical blood chemistry	HDL cholesterol (plasma HDL)	2.7959	2.9992	0.34766	0.648	0.357
clinical blood chemistry	HDL cholesterol to total cholesterol ratio	-0.021964	0.014345	-1.3116	0.453	0.134
clinical blood chemistry	phosphorus (plasma phosphate)	0.79916	0.38333	1.1390	0.209	0.0439
clinical blood chemistry	total bilirubin (plasma TBIL)	0.0043945	0.010440	0.30114	0.874	0.676
clinical blood chemistry	total cholesterol (plasma CHOL, no fast)	4.8604	3.2891	0.61455	0.426	0.148
clinical blood chemistry	total protein (plasma TP)	1.9619	0.71800	1.3586	0.0974	0.00949
clinical blood chemistry	triglyceride (plasma TG, no fast)	7.6354	7.9518	0.63198	0.624	0.343
EKG	duration of PQ interval	0.68375	0.60087	0.86716	0.797	0.264
EKG	duration of PR interval	0.58500	0.68049	0.68975	0.877	0.397
EKG	duration of QRS interval	-0.028750	0.37059	-0.21936	0.991	0.939
EKG	duration of QT interval	-0.19777	0.55905	-0.034261	0.938	0.726
EKG	duration of QTC interval, calculated by dividing QT interval by square root of preceding RR interval	0.62092	0.68965	0.74182	0.878	0.375
EKG	duration of RR interval	-1.0946	0.92694	-0.33032	0.672	0.247
EKG	duration of ST interval	-0.20500	0.59906	0.0080600	0.953	0.735
EKG	heart rate coefficient of variation (signal intensity)	0.65350	1.0641	0.62472	0.900	0.544
EKG	heart rate variability, mean of differences between sequential beats; beats per min	5.4575	7.9186	0.69487	0.887	0.496
EKG	heart rate, beats per min	14.868	8.3603	0.65375	0.443	0.0858
EKG	mean R amplitude, mean amplitude of signal measured from isoelectric line to peak of QRS	0.021154	0.10873	0.059525	0.955	0.847
EKG	mean SR amplitude, mean amplitude of signal measured from signal minimum line to peak of QRS	-0.10508	0.14678	-0.67893	0.768	0.480
EKG	number of signals	-0.26361	4.3067	-0.12526	0.993	0.952
EKG	proportion of number pairs of successive beat-to-beat intervals that exceed 50 ms	-2.6042	3.0502	-0.41441	0.848	0.400
EKG	QT dispersion, measured as inter-lead variability of QT intervals	-3.9921	3.3889	-1.1291	0.881	0.248
EKG	QTc dispersion, calculated as rate-corrected QT dispersion	-3.0448	4.1792	-0.82112	0.931	0.472
EKG	root mean square of successive differences of neighboring RR intervals	1.0152	2.1209	0.67196	0.929	0.636
glucose tolerance test	amount glucose injected	0.063444	2.0633	0.40025	0.987	0.976
glucose tolerance test	plasma glucose, 0min	25.566	5.9695	1.9295	0.00207	0.0000880
glucose tolerance test	plasma glucose, 15min	-89.030	27.534	-2.3317	0.0475	0.00221
glucose tolerance test	plasma glucose, 30min	-72.811	23.943	-1.9757	0.0644	0.00381
glucose tolerance test	plasma glucose, 60min	-10.037	17.026	-0.31395	0.818	0.558
glucose tolerance test	plasma glucose, 120min	10.068	11.405	0.57680	0.666	0.382
grip strength	body weight (at time of grip strength test)	-0.39584	0.51733	-0.17201	0.637	0.449
grip strength	forelimb and hindlimb grip strength (mean of trials), average	-10.330	7.8025	-0.48122	0.392	0.193
grip strength	forelimb and hindlimb grip strength (mean of trials), average normalized to bw	-0.39912	0.38378	-0.37299	0.516	0.305
grip strength	forelimb and hindlimb grip strength by trial, trial1	-6.2135	10.847	-0.18402	0.804	0.570
grip strength	forelimb and hindlimb grip strength by trial, trial2	-13.641	11.616	-0.63401	0.502	0.248
grip strength	forelimb and hindlimb grip strength by trial, trial3	-9.2791	11.117	-0.40274	0.668	0.409
grip strength	forelimb grip strength (mean of trials), average	-10.758	5.7640	-1.0141	0.256	0.0695
grip strength	forelimb grip strength (mean of trials), average normalized to bw	-0.37537	0.28090	-0.71798	0.449	0.189
grip strength	forelimb grip strength by trial, trial1	-14.552	7.4109	-1.3071	0.295	0.0567
grip strength	forelimb grip strength by trial, trial2	-7.6037	8.2119	-0.61460	0.685	0.360
grip strength	forelimb grip strength by trial, trial3	-7.7417	5.7294	-0.59715	0.494	0.185
heart weight	heart weight, normalized to body weight	0.26084	0.11287	0.44759	0.112	0.0244
heart weight	heart weight, weight	6.7727	2.7210	0.51435	0.0879	0.0158
hematology	basophil differential (percent of total WBC)	-0.034711	0.053730	-0.51309	0.838	0.522
hematology	calculated hemoglobin (cHGB)	0.37092	0.19333	0.89328	0.264	0.0628
hematology	eosinophil differential (percent of total WBC)	0.045999	0.24713	0.20589	0.953	0.853
hematology	hematocrit (HCT)	1.1254	0.50475	0.93448	0.205	0.0319
hematology	hemoglobin concentration distribution width (HDW)	-0.077288	0.023106	-1.8835	0.0422	0.00193
hematology	large unstained cells (percent of total WBC)	-0.15592	0.11727	-0.99127	0.541	0.192
hematology	lymphocyte differential (percent of total WBC)	-0.55317	1.2674	-0.28395	0.823	0.665
hematology	mean corpuscular hemoglobin (CHr)	0.077315	0.049279	0.64399	0.325	0.125
hematology	mean platelet volume (MPV)	0.25436	0.073645	1.1867	0.0131	0.00140
hematology	mean RBC corpuscular hemoglobin (MCH)	0.091855	0.19288	0.32897	0.849	0.637
hematology	mean RBC corpuscular hemoglobin concentration (MCHC)	0.058273	0.45035	0.15679	0.961	0.898
hematology	mean RBC corpuscular volume (MCV)	0.079872	0.32845	0.18557	0.917	0.809
hematology	measured hemoglobin (mHGB)	0.46741	0.22107	0.97950	0.239	0.0413
hematology	monocyte differential (percent of total WBC)	0.061359	0.40519	0.42973	0.955	0.880
hematology	neutrophil differential (percent of total WBC)	0.15345	1.8729	0.088956	0.970	0.935
hematology	platelet count (PLT; units per volume x 10³)	71.839	49.934	0.96669	0.538	0.159
hematology	RBC corpuscular distribution width (RDW)	-0.17081	0.16931	-0.63082	0.579	0.320
hematology	RBC corpuscular hemoglobin concentration mean (CHCM)	0.040922	0.21809	0.095886	0.940	0.852
hematology	red blood cell count (RBC; per volume x 10⁶)	0.23547	0.13545	0.67449	0.324	0.0905
hematology	reticulocyte count (Retic; units per volume x 10⁹)	-8.1863	13.960	-0.27183	0.838	0.561
hematology	reticulocyte differential (percent of total RBC)	-0.19529	0.13944	-0.63875	0.521	0.170
hematology	white blood cell count (WBC; units per volume x 10³)	-1.3300	0.60440	-0.73673	0.129	0.0343
holeboard	number of hole pokes by individual hole number, 20 min test, 1	-2.1183	0.83836	-1.9973	0.353	0.0163
holeboard	number of hole pokes by individual hole number, 20 min test, 2	-1.2760	0.46763	-1.7617	0.357	0.0100
holeboard	number of hole pokes by individual hole number, 20 min test, 3	-0.57602	0.48913	-0.88824	0.745	0.247
holeboard	number of hole pokes by individual hole number, 20 min test, 4	-0.99989	0.82159	-0.95270	0.695	0.232
holeboard	number of hole pokes by individual hole number, 20 min test, 5	-0.94817	0.55363	-1.4225	0.614	0.0959
holeboard	number of hole pokes by individual hole number, 20 min test, 6	-0.079492	0.47242	-0.18491	0.980	0.867
holeboard	number of hole pokes by individual hole number, 20 min test, 7	0.29189	0.34500	0.75244	0.887	0.403
holeboard	number of hole pokes by individual hole number, 20 min test, 8	-0.41564	0.58853	-0.59247	0.871	0.485
holeboard	number of hole pokes by individual hole number, 20 min test, 9	-0.99650	0.62756	-1.5780	0.573	0.122
holeboard	number of hole pokes by individual hole number, 20 min test, 10	-0.45442	0.27602	-1.3058	0.711	0.109
holeboard	number of hole pokes by individual hole number, 20 min test, 11	-0.13013	0.26036	-0.31953	0.918	0.620
holeboard	number of hole pokes by individual hole number, 20 min test, 12	-1.8194	0.67114	-2.6489	0.228	0.0104
holeboard	number of hole pokes by individual hole number, 20 min test, 13	-2.6519	1.1367	-2.5964	0.374	0.0257
holeboard	number of hole pokes by individual hole number, 20 min test, 14	-1.4065	0.49184	-2.1407	0.261	0.00720
holeboard	number of hole pokes by individual hole number, 20 min test, 15	-1.7225	0.50656	-2.4055	0.169	0.00173
holeboard	number of hole pokes by individual hole number, 20 min test, 16	-2.9195	0.81780	-2.4714	0.101	0.00109
holeboard	total number of hole pokes, 20 min test	-19.051	5.2764	-2.4714	0.0363	0.000973
light / dark	fecal boli count, 20 min test	1.5225	0.95707	1.5424	0.512	0.117
light / dark	latency to enter dark zone, 20 min test	18.313	41.837	0.25698	0.899	0.663
light / dark	number of transitions between light and dark zones, 20 min test	-17.578	7.5018	-1.6433	0.176	0.0225
light / dark	percentage of total time in dark zone, 20 min test	1.9606	4.3158	0.48630	0.883	0.651
light / dark	percentage of total time in light zone, 20 min test	-1.9606	4.3158	-0.48782	0.883	0.651
light / dark	time mobile in dark zone, 20 min test	-36.453	13.217	-1.9020	0.0800	0.00773
light / dark	time mobile in light zone, 20 min test	-6.2193	12.721	-0.71493	0.816	0.627
light / dark	time spent in dark zone, 20 min test	-21.790	46.609	-0.12471	0.889	0.642
light / dark	time spent in light zone, 20 min test	21.790	46.609	0.12471	0.889	0.642
open field	average speed in center of arena, 20 min test	-0.52098	0.42600	-1.0764	0.574	0.226
open field	average speed in periphery of arena, 20 min test	-0.16130	0.15020	-1.1435	0.513	0.287
open field	distance traveled habituation ratio, 20 min test	11.562	8.4925	0.94445	0.497	0.179
open field	distance traveled in center of arena, 20 min test	-178.88	80.344	-1.4511	0.143	0.0298
open field	distance traveled in periphery of arena, 20 min test	-101.37	158.98	-0.83475	0.737	0.526
open field	distance traveled slope, 20 min test	10.777	7.8087	0.94655	0.492	0.173
open field	distance traveled, 20 min test, 1st 5min	-137.50	83.183	-1.3850	0.296	0.104
open field	distance traveled, 20 min test, 2nd 5min	-60.079	51.846	-1.1886	0.483	0.251
open field	distance traveled, 20 min test, 3rd 5min	-49.191	56.467	-1.0116	0.639	0.387
open field	distance traveled, 20 min test, 4th 5min	-36.301	48.497	-0.87539	0.691	0.457
open field	number of clockwise revolution episodes, 20 min test	-1.3250	1.0806	-1.2388	0.581	0.225
open field	number of counter-clockwise revolution episodes, 20 min test	-1.3307	1.1669	-1.1384	0.547	0.259
open field	number of fecal boli, 20 min test	1.2865	1.0002	1.2045	0.528	0.203
open field	number of rears in 5 min bins, 20 min test, 1st 5min	-1.8875	2.0474	-0.70948	0.622	0.360
open field	number of rears in 5 min bins, 20 min test, 2nd 5min	2.2022	2.4695	0.21581	0.652	0.376
open field	number of rears in 5 min bins, 20 min test, 3rd 5min	5.9279	2.5475	1.0297	0.145	0.0235
open field	number of rears in 5 min bins, 20 min test, 4th 5min	0.53094	2.4111	-0.24199	0.920	0.826
open field	percentage of total time in center of arena, 20 min test	-3.7861	1.8489	-1.1618	0.270	0.0450
open field	percentage of total time in center of arena, slope, 20 min test	-2.2625	1.5354	-1.0504	0.598	0.146
open field	percentage of total time in center, habituation ratio, 20 min test	-2.4224	1.6698	-1.0788	0.624	0.152
open field	percentage of total time in corners of arena, 20 min test	3.4735	3.1818	0.93402	0.587	0.279
open field	percentage of total time in corners, habituation ratio, 20 min test	1.9350	2.2947	0.62271	0.843	0.403
open field	percentage of total time in corners, slope, 20 min test	1.4744	2.1987	0.40193	0.886	0.505
open field	permanence time in center of arena, 20 min test	-45.441	22.186	-1.1618	0.269	0.0450
open field	permanence time in corners of arena, 20 min test	41.689	38.183	0.93402	0.587	0.279
open field	permanence time in periphery of arena, 20 min test	45.468	22.190	1.1566	0.270	0.0449
open field	total distance traveled, 20 min test	-280.25	207.23	-1.2537	0.383	0.181
open field	total number of rears, 20 min test	6.2217	8.2355	0.094795	0.691	0.453
open field	whole arena average speed, 20 min test	-0.23258	0.17283	-1.2537	0.384	0.184
open field	whole arena resting time, 20 min test	34.642	21.430	1.5199	0.270	0.111
open field	whole arena time spent mobile, 20 min test	-34.645	21.422	-1.7549	0.273	0.111
open field	whole arena time spent vertical, 20 min test	18.190	9.3988	1.2960	0.284	0.0578
SHIRPA	locomotor activity (number of squares in the arena the mouse moves into with all four paws in first 30 s of test)	-3.5469	1.8636	-1.2920	0.296	0.0644
startle / PPI	average baseline movement during background noise	-1.2849	1.2472	-0.86746	0.804	0.307
startle / PPI	average of each corrected maximum percent pre-pulse inhibition value	-0.036618	0.059697	-0.42663	0.799	0.542
startle / PPI	average of each corrected percent pre-pulse inhibition value	-0.021229	0.054724	-0.28214	0.878	0.699
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	5.5095	6.2990	0.65744	0.879	0.385
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-11.235	6.1192	-1.1575	0.397	0.0715
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-2.0930	5.7630	-0.32879	0.896	0.718
startle / PPI	average startle response to full pulse (120 dB)	13.381	25.928	0.51430	0.809	0.608
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	12.236	25.603	0.45909	0.810	0.634
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	32.796	24.725	0.86542	0.400	0.190
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	15.302	21.514	0.56454	0.671	0.480
startle / PPI	average startle response to pre-pulse, 74dB sound pressure level	-0.71225	0.99405	-0.47158	0.866	0.477
startle / PPI	average startle response to pre-pulse, 78dB sound pressure level	-0.25583	1.2181	-0.16965	0.972	0.834
startle / PPI	average startle response to pre-pulse, 82dB sound pressure level	0.75806	1.1962	0.19672	0.849	0.529
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	0.067025	0.068696	0.66266	0.869	0.333
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-0.11457	0.069658	-1.0462	0.420	0.105
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-0.021090	0.065372	-0.36546	0.892	0.748
startle / PPI	corrected average startle response to full pulse (120 dB) minus average baseline movement during background noise	14.817	26.047	0.54493	0.784	0.572
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 74dB sound pressure level	13.052	25.640	0.47785	0.796	0.613
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 78dB sound pressure level	33.052	24.882	0.87155	0.396	0.189
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 82dB sound pressure level	14.688	21.751	0.55962	0.691	0.502
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	0.067774	0.072622	0.63842	0.860	0.354
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-0.15248	0.077403	-1.2620	0.304	0.0536
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-0.031348	0.070105	-0.43227	0.840	0.656
startle / PPI	corrected maximum startle response to full pulse (120 dB) minus maximum baseline movement during background noise	43.170	96.178	0.44977	0.841	0.655
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 74dB sound pressure level	56.998	94.386	0.48888	0.747	0.548
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 78dB sound pressure level	127.83	91.720	0.87155	0.375	0.169
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 82dB sound pressure level	54.551	80.537	0.54168	0.687	0.501
startle / PPI	maximum baseline movement during background noise	-3.0672	3.0161	-0.84522	0.775	0.313
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	6.0448	6.9279	0.65396	0.890	0.386
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-14.832	7.1340	-1.3689	0.309	0.0420
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-2.6640	6.4416	-0.39008	0.857	0.681
startle / PPI	maximum startle response to full pulse (120 dB)	40.430	95.868	0.42817	0.850	0.675
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	54.943	94.353	0.48100	0.760	0.563
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	127.63	91.286	0.86542	0.369	0.167
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	55.963	79.761	0.54981	0.674	0.486
startle / PPI	maximum startle response to pre-pulse, 74dB sound pressure level	-1.7028	2.3203	-0.43894	0.840	0.466
startle / PPI	maximum startle response to pre-pulse, 78dB sound pressure level	-0.20583	2.6933	-0.048358	0.996	0.939
startle / PPI	maximum startle response to pre-pulse, 82dB sound pressure level	1.7501	3.4564	0.15970	0.864	0.615

MULTIPLE (CATEGORICAL) TRAIT PROFILE PLOT — Early Adult Phenotyping study (EAP)

In this plot, data points are the computed genotype effect % vs. C57BL/6NJ controls, for all measured categorical phenotypes in JaxKOMP-EAP

Dimensions Width: × Height: px

Plot Options Group by Procedure

Include Sexes Data Both Females Males

Significance Threshold p-Value Threshold

Download Plot

Procedure	JaxKOMP-EAP Trait	Sex	Trait Effect	P-value

eye morphology	anterior chamber depth	females	20.0 %	0.0348
eye morphology	anterior chamber depth	males	0.0 %	1.0
eye morphology	anterior chamber depth	both	7.0 %	0.0495
eye morphology	bulging eye	females	20.0 %	0.0223
eye morphology	bulging eye	males	0.0 %	1.0
eye morphology	bulging eye	both	8.0 %	0.0330
eye morphology	cornea	females	20.0 %	0.0440
eye morphology	cornea	males	2.0 %	1.0
eye morphology	cornea	both	8.0 %	0.0839
eye morphology	cornea opacity	females	20.0 %	0.0423
eye morphology	cornea opacity	males	1.0 %	1.0
eye morphology	cornea opacity	both	8.0 %	0.0715
eye morphology	cornea vascularization	females	20.0 %	0.0311
eye morphology	cornea vascularization	males	1.0 %	1.0
eye morphology	cornea vascularization	both	8.0 %	0.0543
eye morphology	corneal deposits	females	20.0 %	0.0598
eye morphology	corneal deposits	males	1.0 %	1.0
eye morphology	corneal deposits	both	7.0 %	0.0856
eye morphology	corneal mineralization	females	20.0 %	0.0656
eye morphology	corneal mineralization	males	1.0 %	1.0
eye morphology	corneal mineralization	both	8.0 %	0.0482
eye morphology	corneal scleralization	females	20.0 %	0.0380
eye morphology	corneal scleralization	males	1.0 %	1.0
eye morphology	corneal scleralization	both	8.0 %	0.0694
eye morphology	corneal ulcer	females	20.0 %	0.0373
eye morphology	corneal ulcer	males	1.0 %	1.0
eye morphology	corneal ulcer	both	8.0 %	0.0599
eye morphology	eye closure	females	20.0 %	0.0223
eye morphology	eye closure	males	0.0 %	1.0
eye morphology	eye closure	both	8.0 %	0.0328
eye morphology	eye hemorrhage or blood presence	females	20.0 %	0.0438
eye morphology	eye hemorrhage or blood presence	males	1.0 %	1.0
eye morphology	eye hemorrhage or blood presence	both	8.0 %	0.0720
eye morphology	eyelid morphology	females	20.0 %	0.0277
eye morphology	eyelid morphology	males	0.0 %	1.0
eye morphology	eyelid morphology	both	8.0 %	0.0398
eye morphology	eyes (present, absent)	females	20.0 %	0.0273
eye morphology	eyes (present, absent)	males	0.0 %	1.0
eye morphology	eyes (present, absent)	both	8.0 %	0.0403
eye morphology	fusion between cornea and lens	females	19.0 %	0.0905
eye morphology	fusion between cornea and lens	males	2.0 %	1.0
eye morphology	fusion between cornea and lens	both	7.0 %	0.144
eye morphology	iris pigmentation	females	19.0 %	0.107
eye morphology	iris pigmentation	males	1.0 %	1.0
eye morphology	iris pigmentation	both	7.0 %	0.117
eye morphology	iris transillumination	females	19.0 %	0.0939
eye morphology	iris transillumination	males	1.0 %	1.0
eye morphology	iris transillumination	both	7.0 %	0.0946
eye morphology	irispupil	females	19.0 %	0.124
eye morphology	irispupil	males	3.0 %	1.0
eye morphology	irispupil	both	7.0 %	0.132
eye morphology	lacrimation	females	19.0 %	0.161
eye morphology	lacrimation	males	2.0 %	1.0
eye morphology	lacrimation	both	7.0 %	0.206
eye morphology	lens	females	19.0 %	0.158
eye morphology	lens	males	8.0 %	1.0
eye morphology	lens	both	7.0 %	0.283
eye morphology	lens opacity	females	19.0 %	0.145
eye morphology	lens opacity	males	6.0 %	1.0
eye morphology	lens opacity	both	7.0 %	0.317
eye morphology	narrow eye opening	females	20.0 %	0.0101
eye morphology	narrow eye opening	males	1.0 %	1.0
eye morphology	narrow eye opening	both	8.0 %	0.0180
eye morphology	optic disc	females	19.0 %	0.114
eye morphology	optic disc	males	2.0 %	1.0
eye morphology	optic disc	both	7.0 %	0.197
eye morphology	persistence of hyaloid vascular system	females	26.0 %	0.0902
eye morphology	persistence of hyaloid vascular system	males	33.0 %	0.00299
eye morphology	persistence of hyaloid vascular system	both	29.0 %	0.00557
eye morphology	pupil dilation	females	19.0 %	0.111
eye morphology	pupil dilation	males	1.0 %	1.0
eye morphology	pupil dilation	both	7.0 %	0.134
eye morphology	pupil light response	females	19.0 %	0.116
eye morphology	pupil light response	males	12.0 %	0.0388
eye morphology	pupil light response	both	14.0 %	0.0105
eye morphology	pupil position	females	19.0 %	0.138
eye morphology	pupil position	males	12.0 %	0.128
eye morphology	pupil position	both	12.0 %	0.0394
eye morphology	pupil shape	females	19.0 %	0.113
eye morphology	pupil shape	males	2.0 %	1.0
eye morphology	pupil shape	both	7.0 %	0.150
eye morphology	retina	females	19.0 %	0.171
eye morphology	retina	males	22.0 %	0.155
eye morphology	retina	both	18.0 %	0.0695
eye morphology	retinal blood vessels	females	19.0 %	0.0973
eye morphology	retinal blood vessels	males	2.0 %	1.0
eye morphology	retinal blood vessels	both	7.0 %	0.159
eye morphology	retinal blood vessels pattern	females	19.0 %	0.139
eye morphology	retinal blood vessels pattern	males	2.0 %	1.0
eye morphology	retinal blood vessels pattern	both	7.0 %	0.230
eye morphology	retinal blood vessels structure	females	19.0 %	0.104
eye morphology	retinal blood vessels structure	males	2.0 %	1.0
eye morphology	retinal blood vessels structure	both	7.0 %	0.175
eye morphology	retinal pigmentation	females	48.0 %	0.0107
eye morphology	retinal pigmentation	males	11.0 %	0.260
eye morphology	retinal pigmentation	both	26.0 %	0.0152
eye morphology	retinal structure	females	19.0 %	0.106
eye morphology	retinal structure	males	2.0 %	1.0
eye morphology	retinal structure	both	7.0 %	0.181
eye morphology	synechia	females	19.0 %	0.102
eye morphology	synechia	males	2.0 %	1.0
eye morphology	synechia	both	7.0 %	0.162
eye morphology	vitreous	females	19.0 %	0.0956
eye morphology	vitreous	males	2.0 %	1.0
eye morphology	vitreous	both	7.0 %	0.153
SHIRPA	activity body position	females	1.0 %	1.0
SHIRPA	activity body position	males	2.0 %	1.0
SHIRPA	activity body position	both	1.0 %	1.00
SHIRPA	aggression	females	0.0 %	1.00
SHIRPA	aggression	males	1.0 %	1.0
SHIRPA	aggression	both	1.0 %	1.0
SHIRPA	body length	females	0.0 %	1.0
SHIRPA	body length	males	0.0 %	1.00
SHIRPA	body length	both	0.0 %	1.00
SHIRPA	body position	females	0.0 %	1.0
SHIRPA	body position	males	1.0 %	1.0
SHIRPA	body position	both	0.0 %	1.0
SHIRPA	body thickness	females	1.0 %	1.0
SHIRPA	body thickness	males	0.0 %	1.0
SHIRPA	body thickness	both	0.0 %	1.0
SHIRPA	coat color abdomen	females	3.0 %	1.00
SHIRPA	coat color abdomen	males	4.0 %	1.0
SHIRPA	coat color abdomen	both	4.0 %	1.0
SHIRPA	coat color back	females	0.0 %	1.0
SHIRPA	coat color back	males	0.0 %	1.00
SHIRPA	coat color back	both	0.0 %	1.00
SHIRPA	coat color head	females	0.0 %	1.0
SHIRPA	coat color head	males	0.0 %	1.00
SHIRPA	coat color head	both	0.0 %	1.0
SHIRPA	coat color pattern abdomen	females	1.0 %	1.0
SHIRPA	coat color pattern abdomen	males	1.0 %	1.0
SHIRPA	coat color pattern abdomen	both	1.0 %	1.0
SHIRPA	coat color pattern back	females	0.0 %	1.0
SHIRPA	coat color pattern back	males	0.0 %	1.00
SHIRPA	coat color pattern back	both	0.0 %	1.0
SHIRPA	coat color pattern head	females	0.0 %	1.0
SHIRPA	coat color pattern head	males	0.0 %	1.0
SHIRPA	coat color pattern head	both	0.0 %	1.00
SHIRPA	coat hair abdomen texture appearance	females	2.0 %	1.0
SHIRPA	coat hair abdomen texture appearance	males	2.0 %	1.0
SHIRPA	coat hair abdomen texture appearance	both	2.0 %	1.0
SHIRPA	coat hair back texture appearance	females	0.0 %	1.0
SHIRPA	coat hair back texture appearance	males	0.0 %	1.0
SHIRPA	coat hair back texture appearance	both	0.0 %	1.0
SHIRPA	coat hair distribution abdomen	females	0.0 %	1.0
SHIRPA	coat hair distribution abdomen	males	1.0 %	1.00
SHIRPA	coat hair distribution abdomen	both	1.0 %	1.00
SHIRPA	coat hair distribution back	females	0.0 %	1.0
SHIRPA	coat hair distribution back	males	0.0 %	1.0
SHIRPA	coat hair distribution back	both	0.0 %	1.0
SHIRPA	coat hair distribution head	females	1.0 %	1.00
SHIRPA	coat hair distribution head	males	1.0 %	1.0
SHIRPA	coat hair distribution head	both	1.0 %	1.0
SHIRPA	coat hair head texture appearance	females	0.0 %	1.00
SHIRPA	coat hair head texture appearance	males	0.0 %	1.0
SHIRPA	coat hair head texture appearance	both	0.0 %	1.0
SHIRPA	contact righting	females	5.0 %	1.0
SHIRPA	contact righting	males	5.0 %	1.00
SHIRPA	contact righting	both	5.0 %	1.00
SHIRPA	ear morphology	females	0.0 %	1.0
SHIRPA	ear morphology	males	0.0 %	1.0
SHIRPA	ear morphology	both	0.0 %	1.0
SHIRPA	fat distribution	females	0.0 %	1.0
SHIRPA	fat distribution	males	0.0 %	1.0
SHIRPA	fat distribution	both	0.0 %	1.00
SHIRPA	forelimb digit number	females	0.0 %	1.00
SHIRPA	forelimb digit number	males	0.0 %	1.0
SHIRPA	forelimb digit number	both	0.0 %	1.00
SHIRPA	forelimb digit position	females	0.0 %	1.0
SHIRPA	forelimb digit position	males	0.0 %	1.0
SHIRPA	forelimb digit position	both	0.0 %	1.0
SHIRPA	forelimb digit shape	females	0.0 %	1.0
SHIRPA	forelimb digit shape	males	0.0 %	1.0
SHIRPA	forelimb digit shape	both	0.0 %	1.0
SHIRPA	forelimb digit size	females	0.0 %	1.0
SHIRPA	forelimb digit size	males	0.0 %	1.0
SHIRPA	forelimb digit size	both	0.0 %	1.0
SHIRPA	forelimb footpads	females	0.0 %	1.0
SHIRPA	forelimb footpads	males	0.0 %	1.0
SHIRPA	forelimb footpads	both	0.0 %	1.0
SHIRPA	forelimb nail length	females	0.0 %	1.0
SHIRPA	forelimb nail length	males	0.0 %	1.0
SHIRPA	forelimb nail length	both	0.0 %	1.0
SHIRPA	forelimb nail number	females	0.0 %	1.0
SHIRPA	forelimb nail number	males	0.0 %	1.0
SHIRPA	forelimb nail number	both	0.0 %	1.0
SHIRPA	forelimb nail position	females	0.0 %	1.0
SHIRPA	forelimb nail position	males	0.0 %	1.0
SHIRPA	forelimb nail position	both	0.0 %	1.0
SHIRPA	forelimb nail shape	females	0.0 %	1.0
SHIRPA	forelimb nail shape	males	0.0 %	1.0
SHIRPA	forelimb nail shape	both	0.0 %	1.0
SHIRPA	forelimbs position	females	0.0 %	1.0
SHIRPA	forelimbs position	males	0.0 %	1.0
SHIRPA	forelimbs position	both	0.0 %	1.0
SHIRPA	forelimbs shape	females	0.0 %	1.0
SHIRPA	forelimbs shape	males	0.0 %	1.0
SHIRPA	forelimbs shape	both	0.0 %	1.0
SHIRPA	forelimbs size	females	0.0 %	1.0
SHIRPA	forelimbs size	males	0.0 %	1.0
SHIRPA	forelimbs size	both	0.0 %	1.0
SHIRPA	forepaw position	females	0.0 %	1.0
SHIRPA	forepaw position	males	0.0 %	1.0
SHIRPA	forepaw position	both	0.0 %	1.0
SHIRPA	forepaw shape	females	0.0 %	1.0
SHIRPA	forepaw shape	males	0.0 %	1.0
SHIRPA	forepaw shape	both	0.0 %	1.0
SHIRPA	forepaw size	females	0.0 %	1.0
SHIRPA	forepaw size	males	0.0 %	1.0
SHIRPA	forepaw size	both	0.0 %	1.0
SHIRPA	gait (fluidity)	females	0.0 %	1.0
SHIRPA	gait (fluidity)	males	0.0 %	1.00
SHIRPA	gait (fluidity)	both	0.0 %	1.00
SHIRPA	genitalia morphology	females	0.0 %	1.00
SHIRPA	genitalia morphology	males	0.0 %	1.0
SHIRPA	genitalia morphology	both	0.0 %	1.00
SHIRPA	genitalia presence	females	0.0 %	1.0
SHIRPA	genitalia presence	males	0.0 %	1.0
SHIRPA	genitalia presence	both	0.0 %	1.0
SHIRPA	genitalia size	females	0.0 %	1.0
SHIRPA	genitalia size	males	0.0 %	1.0
SHIRPA	genitalia size	both	0.0 %	1.0
SHIRPA	head bobbing	females	0.0 %	1.0
SHIRPA	head bobbing	males	0.0 %	1.0
SHIRPA	head bobbing	both	0.0 %	1.0
SHIRPA	head morphology	females	0.0 %	1.0
SHIRPA	head morphology	males	0.0 %	1.00
SHIRPA	head morphology	both	0.0 %	1.0
SHIRPA	head size	females	0.0 %	1.0
SHIRPA	head size	males	0.0 %	1.0
SHIRPA	head size	both	0.0 %	1.00
SHIRPA	hindlimb digit number	females	1.0 %	1.00
SHIRPA	hindlimb digit number	males	0.0 %	1.0
SHIRPA	hindlimb digit number	both	0.0 %	1.00
SHIRPA	hindlimb digit position	females	0.0 %	1.0
SHIRPA	hindlimb digit position	males	0.0 %	1.0
SHIRPA	hindlimb digit position	both	0.0 %	1.0
SHIRPA	hindlimb digit shape	females	0.0 %	1.0
SHIRPA	hindlimb digit shape	males	0.0 %	1.0
SHIRPA	hindlimb digit shape	both	0.0 %	1.0
SHIRPA	hindlimb digit size	females	0.0 %	1.00
SHIRPA	hindlimb digit size	males	0.0 %	1.0
SHIRPA	hindlimb digit size	both	0.0 %	1.00
SHIRPA	hindlimb nail length	females	0.0 %	1.0
SHIRPA	hindlimb nail length	males	0.0 %	1.0
SHIRPA	hindlimb nail length	both	0.0 %	1.00
SHIRPA	hindlimb nail number	females	0.0 %	1.0
SHIRPA	hindlimb nail number	males	1.0 %	1.0
SHIRPA	hindlimb nail number	both	0.0 %	1.00
SHIRPA	hindlimb nail position	females	0.0 %	1.0
SHIRPA	hindlimb nail position	males	0.0 %	1.0
SHIRPA	hindlimb nail position	both	0.0 %	1.0
SHIRPA	hindlimb nail shape	females	0.0 %	1.0
SHIRPA	hindlimb nail shape	males	0.0 %	1.0
SHIRPA	hindlimb nail shape	both	0.0 %	1.0
SHIRPA	hindlimbs footpads	females	0.0 %	1.0
SHIRPA	hindlimbs footpads	males	0.0 %	1.0
SHIRPA	hindlimbs footpads	both	0.0 %	1.0
SHIRPA	hindlimbs position	females	0.0 %	1.0
SHIRPA	hindlimbs position	males	0.0 %	1.0
SHIRPA	hindlimbs position	both	0.0 %	1.0
SHIRPA	hindlimbs shape	females	0.0 %	1.0
SHIRPA	hindlimbs shape	males	0.0 %	1.0
SHIRPA	hindlimbs shape	both	0.0 %	1.0
SHIRPA	hindlimbs size	females	0.0 %	1.0
SHIRPA	hindlimbs size	males	0.0 %	1.0
SHIRPA	hindlimbs size	both	0.0 %	1.0
SHIRPA	hindpaw position	females	0.0 %	1.0
SHIRPA	hindpaw position	males	0.0 %	1.0
SHIRPA	hindpaw position	both	0.0 %	1.0
SHIRPA	hindpaw shape	females	0.0 %	1.0
SHIRPA	hindpaw shape	males	0.0 %	1.0
SHIRPA	hindpaw shape	both	0.0 %	1.0
SHIRPA	hindpaw size	females	0.0 %	1.0
SHIRPA	hindpaw size	males	0.0 %	1.0
SHIRPA	hindpaw size	both	0.0 %	1.0
SHIRPA	limb grasp	females	9.0 %	1.00
SHIRPA	limb grasp	males	7.0 %	0.375
SHIRPA	limb grasp	both	1.0 %	1.0
SHIRPA	lower lip morphology	females	0.0 %	1.0
SHIRPA	lower lip morphology	males	0.0 %	1.0
SHIRPA	lower lip morphology	both	0.0 %	1.0
SHIRPA	lower teeth appearance	females	0.0 %	1.0
SHIRPA	lower teeth appearance	males	0.0 %	1.00
SHIRPA	lower teeth appearance	both	0.0 %	1.00
SHIRPA	mouth morphology	females	0.0 %	1.0
SHIRPA	mouth morphology	males	0.0 %	1.00
SHIRPA	mouth morphology	both	0.0 %	1.00
SHIRPA	salivation	females	0.0 %	1.0
SHIRPA	salivation	males	0.0 %	1.0
SHIRPA	salivation	both	0.0 %	1.0
SHIRPA	skin color back paws	females	0.0 %	1.0
SHIRPA	skin color back paws	males	0.0 %	1.0
SHIRPA	skin color back paws	both	0.0 %	1.0
SHIRPA	skin color ear	females	0.0 %	1.0
SHIRPA	skin color ear	males	0.0 %	1.0
SHIRPA	skin color ear	both	0.0 %	1.0
SHIRPA	skin color front paws	females	0.0 %	1.0
SHIRPA	skin color front paws	males	0.0 %	1.0
SHIRPA	skin color front paws	both	0.0 %	1.0
SHIRPA	skin color snout	females	0.0 %	1.0
SHIRPA	skin color snout	males	0.0 %	1.0
SHIRPA	skin color snout	both	0.0 %	1.0
SHIRPA	skin color tail	females	0.0 %	1.0
SHIRPA	skin color tail	males	0.0 %	1.0
SHIRPA	skin color tail	both	0.0 %	1.0
SHIRPA	skin color whole body	females	0.0 %	1.0
SHIRPA	skin color whole body	males	0.0 %	1.0
SHIRPA	skin color whole body	both	0.0 %	1.0
SHIRPA	skin texture back paw	females	0.0 %	1.0
SHIRPA	skin texture back paw	males	0.0 %	1.0
SHIRPA	skin texture back paw	both	0.0 %	1.0
SHIRPA	skin texture ear	females	0.0 %	1.0
SHIRPA	skin texture ear	males	0.0 %	1.0
SHIRPA	skin texture ear	both	0.0 %	1.0
SHIRPA	skin texture front paws	females	0.0 %	1.0
SHIRPA	skin texture front paws	males	0.0 %	1.0
SHIRPA	skin texture front paws	both	0.0 %	1.0
SHIRPA	skin texture snout	females	0.0 %	1.0
SHIRPA	skin texture snout	males	0.0 %	1.0
SHIRPA	skin texture snout	both	0.0 %	1.0
SHIRPA	skin texture tail	females	0.0 %	1.0
SHIRPA	skin texture tail	males	0.0 %	1.0
SHIRPA	skin texture tail	both	0.0 %	1.0
SHIRPA	skin texture whole body	females	0.0 %	1.0
SHIRPA	skin texture whole body	males	0.0 %	1.00
SHIRPA	skin texture whole body	both	0.0 %	1.00
SHIRPA	snout size	females	0.0 %	1.0
SHIRPA	snout size	males	1.0 %	1.0
SHIRPA	snout size	both	0.0 %	1.0
SHIRPA	startle response	females	0.0 %	1.00
SHIRPA	startle response	males	0.0 %	1.00
SHIRPA	startle response	both	0.0 %	1.00
SHIRPA	tail curvature	females	0.0 %	1.00
SHIRPA	tail curvature	males	0.0 %	1.0
SHIRPA	tail curvature	both	0.0 %	1.0
SHIRPA	tail elevation	females	1.0 %	1.00
SHIRPA	tail elevation	males	2.0 %	1.0
SHIRPA	tail elevation	both	1.0 %	1.0
SHIRPA	tail length	females	0.0 %	1.0
SHIRPA	tail length	males	0.0 %	1.0
SHIRPA	tail length	both	0.0 %	1.00
SHIRPA	tail morphology	females	0.0 %	1.00
SHIRPA	tail morphology	males	0.0 %	1.0
SHIRPA	tail morphology	both	0.0 %	1.00
SHIRPA	tail presence	females	0.0 %	1.0
SHIRPA	tail presence	males	0.0 %	1.0
SHIRPA	tail presence	both	0.0 %	1.0
SHIRPA	tail shape	females	0.0 %	1.0
SHIRPA	tail shape	males	0.0 %	1.0
SHIRPA	tail shape	both	0.0 %	1.00
SHIRPA	tail thickness	females	0.0 %	1.0
SHIRPA	tail thickness	males	0.0 %	1.0
SHIRPA	tail thickness	both	0.0 %	1.0
SHIRPA	teeth presence	females	0.0 %	1.0
SHIRPA	teeth presence	males	0.0 %	1.00
SHIRPA	teeth presence	both	0.0 %	1.00
SHIRPA	transfer arousal	females	1.0 %	1.0
SHIRPA	transfer arousal	males	2.0 %	1.00
SHIRPA	transfer arousal	both	1.0 %	1.0
SHIRPA	tremor	females	0.0 %	1.0
SHIRPA	tremor	males	0.0 %	1.0
SHIRPA	tremor	both	0.0 %	1.00
SHIRPA	trunk curl	females	0.0 %	1.00
SHIRPA	trunk curl	males	0.0 %	1.0
SHIRPA	trunk curl	both	0.0 %	1.0
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	females	0.0 %	1.0
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	males	0.0 %	1.0
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	both	0.0 %	1.00
SHIRPA	upper lip morphology	females	0.0 %	1.0
SHIRPA	upper lip morphology	males	0.0 %	1.0
SHIRPA	upper lip morphology	both	0.0 %	1.0
SHIRPA	upper teeth appearance	females	0.0 %	1.0
SHIRPA	upper teeth appearance	males	0.0 %	1.0
SHIRPA	upper teeth appearance	both	0.0 %	1.00
SHIRPA	vibrissae appearance	females	2.0 %	1.0
SHIRPA	vibrissae appearance	males	1.0 %	1.0
SHIRPA	vibrissae appearance	both	1.0 %	1.0
SHIRPA	vibrissae presence	females	2.0 %	1.00
SHIRPA	vibrissae presence	males	1.0 %	1.0
SHIRPA	vibrissae presence	both	2.0 %	1.0
SHIRPA	vocalization	females	2.0 %	1.00
SHIRPA	vocalization	males	2.0 %	1.0
SHIRPA	vocalization	both	2.0 %	1.00

GENOTYPE CORRELATION PLOT

Correlate Dnajc30^{tm1.1(KOMP)Vlcg}/2J -/- with genotype: