MPD: JaxKOMP-EAP genotype: Slc35c2<sup>tm1.1(KOMP)Vlcg</sup> -/-

JaxKOMP-EAP effect sizes: Slc35c2^{tm1.1(KOMP)Vlcg} -/- Gene Slc35c2

MULTIPLE (NUMERIC) TRAIT PROFILE PLOT — Early Adult Phenotyping study (EAP)

Procedure	JaxKOMP-EAP Trait	Trait Effect	Trait Effect SE	Trait Effect RankZ	Adjusted p-value	Unadjusted p-value
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 12 kHz pip	-1.0515	1.9793	-0.22215	0.886	0.607
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 18 kHz pip	-4.4178	1.2148	-1.0857	0.0894	0.00456
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 24 kHz pip	17.178	3.0399	2.1514	0.0130	0.000212
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 30 kHz pip	-1.0370	4.7538	-0.19183	0.936	0.832
body composition	body length	-0.085254	0.050383	-0.76757	0.330	0.0984
body composition	body weight (at time of DXA)	-1.3783	0.49786	-0.86400	0.0495	0.00842
body composition	bone area, whole body scan, head excluded	-0.16980	0.14166	-0.50538	0.508	0.238
body composition	bone mineral content of whole body scan, head excluded	-0.0040709	0.010777	-0.10257	0.867	0.708
body composition	bone mineral content to body weight ratio	-0.00042099	0.00043840	-0.35986	0.608	0.343
body composition	bone mineral density of whole body scan, head excluded	0.00049164	0.00054699	0.57444	0.668	0.374
body composition	fat tissue mass of whole body scan, head excluded	0.34327	0.34622	0.56206	0.587	0.327
body composition	fat tissue mass to body weight ratio	0.010188	0.011899	0.51939	0.628	0.397
body composition	lean tissue mass of whole body scan, head excluded	0.0034485	0.25807	-0.14661	0.998	0.989
body composition	lean tissue mass to body weight ratio	-0.013294	0.010323	-0.77717	0.457	0.205
body composition	percent fat, whole body scan, head excluded	1.0445	1.1441	0.56686	0.613	0.367
body composition	ratio of soft-tissue attenuation coefficients	-0.0011539	0.0012714	-0.57308	0.614	0.370
body composition	tissue area	0.082208	0.19479	0.48897	0.874	0.675
body composition	total tissue mass, whole body scan, head excluded	0.34480	0.22228	0.51939	0.344	0.129
clinical blood chemistry	alanine transaminase (plasma ALT)	6.3382	3.6256	0.49167	0.438	0.0938
clinical blood chemistry	albumin (plasma Alb)	0.10027	0.56617	0.20387	0.951	0.861
clinical blood chemistry	alkaline phosphatase (plasma ALP)	9.6882	5.2742	1.0694	0.256	0.0798
clinical blood chemistry	aspartate transaminase (plasma AST)	14.417	4.6111	0.59471	0.0882	0.00474
clinical blood chemistry	aspartate transaminase to alanine transaminase ratio (plasma AST:ALT)	0.020128	0.16428	0.092391	0.972	0.904
clinical blood chemistry	blood urea nitrogen (BUN)	-1.5933	1.4450	-0.68578	0.547	0.282
clinical blood chemistry	calcium (plasma Ca)	-0.026672	0.082187	0.16352	0.868	0.749
clinical blood chemistry	creatinine (plasma)	-0.049218	0.024859	-0.96905	0.224	0.0604
clinical blood chemistry	glucose (plasma GLU, no fast)	-25.199	10.040	-0.63162	0.0823	0.0196
clinical blood chemistry	HDL cholesterol (plasma HDL)	-0.86115	2.1604	-0.54352	0.883	0.694
clinical blood chemistry	HDL cholesterol to total cholesterol ratio	0.019762	0.011840	0.96856	0.414	0.109
clinical blood chemistry	phosphorus (plasma phosphate)	0.31667	0.22644	0.43438	0.440	0.175
clinical blood chemistry	total bilirubin (plasma TBIL)	0.018141	0.0079862	1.1146	0.213	0.0328
clinical blood chemistry	total cholesterol (plasma CHOL, no fast)	-4.2861	3.4808	-0.92479	0.545	0.231
clinical blood chemistry	total protein (plasma TP)	0.11981	0.80282	0.028553	0.948	0.883
clinical blood chemistry	triglyceride (plasma TG, no fast)	-8.4379	12.059	-0.25453	0.737	0.491
EKG	duration of PQ interval	-2.4377	1.0520	-2.1425	0.617	0.0814
EKG	duration of PR interval	-2.9161	0.88441	-2.2553	0.469	0.0300
EKG	duration of QRS interval	-0.37302	0.32435	-1.1641	0.885	0.314
EKG	duration of QT interval	-1.4896	0.83810	-1.1842	0.665	0.150
EKG	duration of QTC interval, calculated by dividing QT interval by square root of preceding RR interval	-1.1436	0.89161	-1.1140	0.815	0.269
EKG	duration of RR interval	-1.8646	1.3447	-0.72075	0.659	0.238
EKG	duration of ST interval	-1.1175	0.80218	-0.83818	0.730	0.236
EKG	heart rate coefficient of variation (signal intensity)	1.1273	1.2625	1.0012	0.871	0.422
EKG	heart rate variability, mean of differences between sequential beats; beats per min	9.3793	9.1442	1.1330	0.853	0.363
EKG	heart rate, beats per min	17.171	10.381	0.77073	0.568	0.173
EKG	mean R amplitude, mean amplitude of signal measured from isoelectric line to peak of QRS	0.037333	0.093820	0.20202	0.903	0.711
EKG	mean SR amplitude, mean amplitude of signal measured from signal minimum line to peak of QRS	0.081875	0.13240	0.36380	0.822	0.570
EKG	number of signals	-0.89583	3.5911	-0.22556	0.964	0.815
EKG	proportion of number pairs of successive beat-to-beat intervals that exceed 50 ms	0.34993	5.9654	0.14702	0.991	0.956
EKG	QT dispersion, measured as inter-lead variability of QT intervals	-0.21672	2.4513	-0.024182	0.989	0.934
EKG	QTc dispersion, calculated as rate-corrected QT dispersion	-0.062359	2.5941	-0.014105	0.996	0.982
EKG	root mean square of successive differences of neighboring RR intervals	0.12082	1.6630	0.16394	0.989	0.946
glucose tolerance test	amount glucose injected	3.5883	2.1569	1.3015	0.437	0.104
glucose tolerance test	plasma glucose, 0min	1.4296	4.7077	-0.086591	0.880	0.763
glucose tolerance test	plasma glucose, 15min	6.4932	16.946	0.29956	0.895	0.704
glucose tolerance test	plasma glucose, 30min	32.424	13.915	1.0770	0.172	0.0248
glucose tolerance test	plasma glucose, 60min	16.024	10.554	0.74968	0.430	0.137
glucose tolerance test	plasma glucose, 120min	20.625	9.6066	1.2349	0.248	0.0379
grip strength	body weight (at time of grip strength test)	-1.4030	0.38231	-0.99085	0.00904	0.00110
grip strength	forelimb and hindlimb grip strength (mean of trials), average	-22.553	6.5168	-1.3105	0.0181	0.00187
grip strength	forelimb and hindlimb grip strength (mean of trials), average normalized to bw	-1.4219	0.42887	-1.7247	0.0250	0.00280
grip strength	forelimb and hindlimb grip strength by trial, trial1	-13.989	9.5295	-0.67540	0.417	0.154
grip strength	forelimb and hindlimb grip strength by trial, trial2	-27.115	8.3516	-1.4837	0.0419	0.00321
grip strength	forelimb and hindlimb grip strength by trial, trial3	-35.319	10.959	-1.8875	0.0420	0.00351
grip strength	forelimb grip strength (mean of trials), average	-12.130	5.9716	-1.1870	0.214	0.0526
grip strength	forelimb grip strength (mean of trials), average normalized to bw	-0.19832	0.31593	-0.27953	0.768	0.536
grip strength	forelimb grip strength by trial, trial1	-14.903	7.1662	-1.3492	0.283	0.0476
grip strength	forelimb grip strength by trial, trial2	-15.443	7.0974	-1.3313	0.239	0.0388
grip strength	forelimb grip strength by trial, trial3	-6.0432	6.3794	-0.42489	0.680	0.352
heart weight	heart weight, normalized to body weight	0.16364	0.14053	0.13895	0.476	0.257
heart weight	heart weight, weight	5.1432	3.8070	0.28980	0.393	0.191
hematology	basophil differential (percent of total WBC)	0.16407	0.037408	1.7837	0.0429	0.000235
hematology	calculated hemoglobin (cHGB)	0.26454	0.20494	0.55578	0.495	0.211
hematology	eosinophil differential (percent of total WBC)	-0.65180	0.24517	-1.5639	0.215	0.0143
hematology	hematocrit (HCT)	0.15913	0.69046	-0.21625	0.911	0.820
hematology	hemoglobin concentration distribution width (HDW)	0.00098272	0.013942	0.019122	0.969	0.944
hematology	large unstained cells (percent of total WBC)	0.0018403	0.20512	0.047788	0.997	0.993
hematology	lymphocyte differential (percent of total WBC)	3.5071	0.86441	1.1405	0.0175	0.000525
hematology	mean corpuscular hemoglobin (CHr)	-0.048254	0.077329	-0.39509	0.749	0.539
hematology	mean platelet volume (MPV)	0.45649	0.10473	1.6258	0.00353	0.000251
hematology	mean RBC corpuscular hemoglobin (MCH)	1.2738	1.7604	2.4255	0.782	0.477
hematology	mean RBC corpuscular hemoglobin concentration (MCHC)	3.5193	2.8131	2.6671	0.592	0.224
hematology	mean RBC corpuscular volume (MCV)	-0.52122	0.30567	-0.93660	0.266	0.103
hematology	measured hemoglobin (mHGB)	1.4642	1.2868	2.4526	0.576	0.267
hematology	monocyte differential (percent of total WBC)	-0.067348	0.12054	-0.010934	0.836	0.582
hematology	neutrophil differential (percent of total WBC)	-2.9172	0.94014	-1.1431	0.0643	0.00519
hematology	platelet count (PLT; units per volume x 10³)	-42.730	46.847	-0.52785	0.704	0.372
hematology	RBC corpuscular distribution width (RDW)	0.034458	0.10619	0.12297	0.868	0.749
hematology	RBC corpuscular hemoglobin concentration mean (CHCM)	0.28319	0.28928	0.69208	0.600	0.339
hematology	red blood cell count (RBC; per volume x 10⁶)	0.21147	0.14342	0.58116	0.409	0.155
hematology	reticulocyte count (Retic; units per volume x 10⁹)	35.699	15.229	1.4314	0.287	0.0285
hematology	reticulocyte differential (percent of total RBC)	0.22202	0.14473	1.1034	0.479	0.139
hematology	white blood cell count (WBC; units per volume x 10³)	-0.54882	0.76499	-0.21346	0.666	0.481
holeboard	number of hole pokes by individual hole number, 20 min test, 1	-1.5247	0.66429	-1.4509	0.396	0.0270
holeboard	number of hole pokes by individual hole number, 20 min test, 2	-0.13079	0.42795	-0.073493	0.951	0.761
holeboard	number of hole pokes by individual hole number, 20 min test, 3	-0.95534	0.59361	-1.5223	0.654	0.115
holeboard	number of hole pokes by individual hole number, 20 min test, 4	-1.3825	0.73889	-1.3069	0.485	0.0687
holeboard	number of hole pokes by individual hole number, 20 min test, 5	-0.84039	0.36246	-1.2720	0.402	0.0256
holeboard	number of hole pokes by individual hole number, 20 min test, 6	-0.31667	0.17772	-0.87874	0.645	0.0824
holeboard	number of hole pokes by individual hole number, 20 min test, 7	-0.53825	0.34100	-1.5004	0.731	0.123
holeboard	number of hole pokes by individual hole number, 20 min test, 8	-0.33333	0.49858	-0.42888	0.876	0.508
holeboard	number of hole pokes by individual hole number, 20 min test, 9	-0.45833	0.40414	-0.72850	0.743	0.264
holeboard	number of hole pokes by individual hole number, 20 min test, 10	0.10833	0.29649	0.36301	0.951	0.717
holeboard	number of hole pokes by individual hole number, 20 min test, 11	-0.0044535	0.24270	-0.0016891	0.998	0.985
holeboard	number of hole pokes by individual hole number, 20 min test, 12	-0.41213	0.37022	-0.61734	0.715	0.272
holeboard	number of hole pokes by individual hole number, 20 min test, 13	-0.99167	0.66908	-0.87874	0.554	0.146
holeboard	number of hole pokes by individual hole number, 20 min test, 14	-0.74583	0.49674	-1.1112	0.574	0.141
holeboard	number of hole pokes by individual hole number, 20 min test, 15	-0.67896	0.40768	-0.99656	0.565	0.104
holeboard	number of hole pokes by individual hole number, 20 min test, 16	-1.2354	0.91617	-1.0507	0.603	0.185
holeboard	total number of hole pokes, 20 min test	-10.548	3.9996	-1.3867	0.118	0.0118
light / dark	fecal boli count, 20 min test	0.65833	0.54346	0.76652	0.630	0.233
light / dark	latency to enter dark zone, 20 min test	19.333	30.700	0.27940	0.850	0.532
light / dark	number of transitions between light and dark zones, 20 min test	-2.5833	7.3072	-0.14927	0.889	0.726
light / dark	percentage of total time in dark zone, 20 min test	-8.1659	5.2624	-1.3470	0.484	0.128
light / dark	percentage of total time in light zone, 20 min test	8.1659	5.2624	1.3436	0.483	0.128
light / dark	time mobile in dark zone, 20 min test	-17.319	14.036	-1.0939	0.523	0.224
light / dark	time mobile in light zone, 20 min test	17.672	11.526	0.75209	0.361	0.133
light / dark	time spent in dark zone, 20 min test	-102.90	65.541	-1.2206	0.533	0.124
light / dark	time spent in light zone, 20 min test	102.90	65.541	1.2206	0.533	0.124
open field	average speed in center of arena, 20 min test	-0.63292	0.33940	-1.2929	0.341	0.0694
open field	average speed in periphery of arena, 20 min test	0.087119	0.15326	-0.15434	0.763	0.573
open field	distance traveled habituation ratio, 20 min test	0.23779	7.8326	0.053057	0.991	0.976
open field	distance traveled in center of arena, 20 min test	72.964	109.49	0.12451	0.717	0.509
open field	distance traveled in periphery of arena, 20 min test	-54.269	136.69	-0.64900	0.840	0.693
open field	distance traveled slope, 20 min test	0.34293	7.4853	0.096144	0.992	0.964
open field	distance traveled, 20 min test, 1st 5min	-19.029	64.876	-0.50311	0.900	0.771
open field	distance traveled, 20 min test, 2nd 5min	22.875	58.368	-0.22819	0.844	0.697
open field	distance traveled, 20 min test, 3rd 5min	25.538	56.562	-0.14619	0.833	0.654
open field	distance traveled, 20 min test, 4th 5min	-21.767	56.073	-0.71335	0.855	0.700
open field	number of clockwise revolution episodes, 20 min test	1.3208	1.5391	0.36960	0.736	0.396
open field	number of counter-clockwise revolution episodes, 20 min test	-0.16939	1.1511	-0.51074	0.952	0.884
open field	number of fecal boli, 20 min test	-1.7064	0.84876	-1.0938	0.276	0.0510
open field	number of rears in 5 min bins, 20 min test, 1st 5min	-2.3792	2.4823	-0.84392	0.606	0.343
open field	number of rears in 5 min bins, 20 min test, 2nd 5min	-3.2917	2.5089	-1.1751	0.487	0.197
open field	number of rears in 5 min bins, 20 min test, 3rd 5min	-0.16003	2.3139	-0.33156	0.969	0.945
open field	number of rears in 5 min bins, 20 min test, 4th 5min	1.4913	3.6743	-0.019469	0.843	0.687
open field	percentage of total time in center of arena, 20 min test	5.1637	3.7299	0.92574	0.486	0.174
open field	percentage of total time in center of arena, slope, 20 min test	1.8087	1.6412	1.1131	0.747	0.277
open field	percentage of total time in center, habituation ratio, 20 min test	2.3932	1.7681	1.4321	0.662	0.183
open field	percentage of total time in corners of arena, 20 min test	-5.5920	4.5508	-0.74665	0.540	0.226
open field	percentage of total time in corners, habituation ratio, 20 min test	-3.8147	1.7556	-1.9480	0.405	0.0356
open field	percentage of total time in corners, slope, 20 min test	-2.8897	1.6092	-1.6899	0.520	0.0799
open field	permanence time in center of arena, 20 min test	61.962	44.757	0.92781	0.487	0.174
open field	permanence time in corners of arena, 20 min test	-67.092	54.610	-0.74665	0.541	0.226
open field	permanence time in periphery of arena, 20 min test	-61.952	44.752	-0.92781	0.486	0.174
open field	total distance traveled, 20 min test	5.9143	192.75	-0.49247	0.987	0.976
open field	total number of rears, 20 min test	-4.3149	8.8469	-0.62597	0.805	0.628
open field	whole arena average speed, 20 min test	0.0054702	0.16050	-0.49095	0.986	0.973
open field	whole arena resting time, 20 min test	-7.3972	20.238	0.35434	0.836	0.717
open field	whole arena time spent mobile, 20 min test	7.3103	20.220	-0.21443	0.844	0.720
open field	whole arena time spent vertical, 20 min test	-9.5375	8.7945	-0.85780	0.594	0.284
SHIRPA	locomotor activity (number of squares in the arena the mouse moves into with all four paws in first 30 s of test)	3.7081	1.5495	1.6395	0.181	0.0245
startle / PPI	average baseline movement during background noise	-2.2653	1.0824	-1.4979	0.541	0.0508
startle / PPI	average of each corrected maximum percent pre-pulse inhibition value	0.15666	0.087975	1.2686	0.402	0.0918
startle / PPI	average of each corrected percent pre-pulse inhibition value	0.21477	0.081464	1.9665	0.196	0.0168
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	15.745	8.6253	1.8947	0.817	0.0846
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	15.382	9.6050	1.5470	0.475	0.127
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	22.183	7.1359	2.2140	0.0838	0.00606
startle / PPI	average startle response to full pulse (120 dB)	-28.233	36.113	-0.35404	0.680	0.445
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-61.701	36.244	-0.91541	0.291	0.106
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-58.938	34.644	-0.92182	0.287	0.106
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-58.944	26.812	-1.1070	0.162	0.0412
startle / PPI	average startle response to pre-pulse, 74dB sound pressure level	1.1980	1.4067	0.80195	0.832	0.406
startle / PPI	average startle response to pre-pulse, 78dB sound pressure level	-0.35228	1.6529	-0.23401	0.972	0.834
startle / PPI	average startle response to pre-pulse, 82dB sound pressure level	-0.59973	1.7857	-0.50473	0.936	0.741
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	0.19884	0.097421	1.9118	0.744	0.0562
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	0.18006	0.10925	1.4638	0.439	0.117
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	0.27447	0.083345	1.8235	0.0505	0.00404
startle / PPI	corrected average startle response to full pulse (120 dB) minus average baseline movement during background noise	-25.967	36.160	-0.31404	0.715	0.482
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 74dB sound pressure level	-61.387	36.355	-0.90904	0.297	0.109
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 78dB sound pressure level	-58.204	34.680	-0.90692	0.295	0.111
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 82dB sound pressure level	-57.951	26.974	-1.0493	0.170	0.0455
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	0.082272	0.10622	0.75081	0.903	0.449
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	0.15927	0.11447	1.1682	0.519	0.181
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	0.24123	0.090930	1.5107	0.113	0.0162
startle / PPI	corrected maximum startle response to full pulse (120 dB) minus maximum baseline movement during background noise	-132.65	131.09	-0.48100	0.567	0.325
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 74dB sound pressure level	-195.16	132.09	-0.80776	0.372	0.157
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 78dB sound pressure level	-204.88	123.64	-0.87155	0.300	0.115
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 82dB sound pressure level	-208.18	100.77	-1.0277	0.184	0.0535
startle / PPI	maximum baseline movement during background noise	-6.3188	2.3903	-1.6365	0.363	0.0165
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	5.0841	9.7827	0.54818	0.938	0.610
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	13.847	10.412	1.1939	0.564	0.200
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	20.875	8.3252	1.8312	0.154	0.0220
startle / PPI	maximum startle response to full pulse (120 dB)	-138.97	131.16	-0.51110	0.549	0.303
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-194.09	132.00	-0.81165	0.374	0.159
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-207.37	123.13	-0.87565	0.291	0.109
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-212.78	100.47	-1.0591	0.176	0.0484
startle / PPI	maximum startle response to pre-pulse, 74dB sound pressure level	4.8164	3.4532	1.2562	0.689	0.181
startle / PPI	maximum startle response to pre-pulse, 78dB sound pressure level	-0.98053	4.6332	-0.25711	0.975	0.835
startle / PPI	maximum startle response to pre-pulse, 82dB sound pressure level	-3.7027	4.2248	-0.94128	0.754	0.392

MULTIPLE (CATEGORICAL) TRAIT PROFILE PLOT — Early Adult Phenotyping study (EAP)

Procedure	JaxKOMP-EAP Trait	Sex	Trait Effect	P-value
eye morphology	anterior chamber depth	females	1.0 %	1.0
eye morphology	anterior chamber depth	males	0.0 %	1.0
eye morphology	anterior chamber depth	both	1.0 %	1.0
eye morphology	bulging eye	females	1.0 %	1.0
eye morphology	bulging eye	males	0.0 %	1.0
eye morphology	bulging eye	both	1.0 %	1.00
eye morphology	cornea	females	4.0 %	1.0
eye morphology	cornea	males	2.0 %	1.0
eye morphology	cornea	both	3.0 %	1.00
eye morphology	cornea opacity	females	5.0 %	1.00
eye morphology	cornea opacity	males	1.0 %	1.0
eye morphology	cornea opacity	both	3.0 %	1.00
eye morphology	cornea vascularization	females	3.0 %	1.0
eye morphology	cornea vascularization	males	1.0 %	1.0
eye morphology	cornea vascularization	both	2.0 %	1.00
eye morphology	corneal deposits	females	2.0 %	1.0
eye morphology	corneal deposits	males	1.0 %	1.0
eye morphology	corneal deposits	both	1.0 %	1.00
eye morphology	corneal mineralization	females	2.0 %	1.0
eye morphology	corneal mineralization	males	1.0 %	1.0
eye morphology	corneal mineralization	both	1.0 %	1.00
eye morphology	corneal scleralization	females	3.0 %	1.00
eye morphology	corneal scleralization	males	1.0 %	1.0
eye morphology	corneal scleralization	both	2.0 %	1.00
eye morphology	corneal ulcer	females	1.0 %	1.0
eye morphology	corneal ulcer	males	1.0 %	1.0
eye morphology	corneal ulcer	both	1.0 %	1.00
eye morphology	eye closure	females	1.0 %	1.00
eye morphology	eye closure	males	0.0 %	1.0
eye morphology	eye closure	both	1.0 %	1.0
eye morphology	eye hemorrhage or blood presence	females	2.0 %	1.00
eye morphology	eye hemorrhage or blood presence	males	1.0 %	1.0
eye morphology	eye hemorrhage or blood presence	both	1.0 %	1.00
eye morphology	eyelid morphology	females	1.0 %	1.0
eye morphology	eyelid morphology	males	0.0 %	1.0
eye morphology	eyelid morphology	both	1.0 %	1.0
eye morphology	eyes (present, absent)	females	1.0 %	1.0
eye morphology	eyes (present, absent)	males	0.0 %	1.0
eye morphology	eyes (present, absent)	both	0.0 %	1.0
eye morphology	fusion between cornea and lens	females	4.0 %	1.00
eye morphology	fusion between cornea and lens	males	2.0 %	1.0
eye morphology	fusion between cornea and lens	both	3.0 %	1.00
eye morphology	iris pigmentation	females	2.0 %	1.0
eye morphology	iris pigmentation	males	1.0 %	1.0
eye morphology	iris pigmentation	both	2.0 %	1.00
eye morphology	iris transillumination	females	2.0 %	1.00
eye morphology	iris transillumination	males	1.0 %	1.0
eye morphology	iris transillumination	both	1.0 %	1.00
eye morphology	irispupil	females	4.0 %	1.00
eye morphology	irispupil	males	3.0 %	1.0
eye morphology	irispupil	both	3.0 %	1.00
eye morphology	lacrimation	females	3.0 %	1.0
eye morphology	lacrimation	males	2.0 %	1.0
eye morphology	lacrimation	both	3.0 %	1.0
eye morphology	lens	females	10.0 %	1.00
eye morphology	lens	males	8.0 %	1.0
eye morphology	lens	both	9.0 %	1.0
eye morphology	lens opacity	females	9.0 %	0.531
eye morphology	lens opacity	males	24.0 %	0.0186
eye morphology	lens opacity	both	11.0 %	0.0718
eye morphology	narrow eye opening	females	2.0 %	1.0
eye morphology	narrow eye opening	males	1.0 %	1.0
eye morphology	narrow eye opening	both	1.0 %	1.0
eye morphology	optic disc	females	4.0 %	1.00
eye morphology	optic disc	males	2.0 %	1.0
eye morphology	optic disc	both	3.0 %	1.00
eye morphology	persistence of hyaloid vascular system	females	10.0 %	0.499
eye morphology	persistence of hyaloid vascular system	males	20.0 %	0.0205
eye morphology	persistence of hyaloid vascular system	both	9.0 %	0.111
eye morphology	pupil dilation	females	2.0 %	1.0
eye morphology	pupil dilation	males	1.0 %	1.0
eye morphology	pupil dilation	both	2.0 %	1.0
eye morphology	pupil light response	females	2.0 %	1.00
eye morphology	pupil light response	males	1.0 %	1.0
eye morphology	pupil light response	both	2.0 %	1.00
eye morphology	pupil position	females	4.0 %	1.00
eye morphology	pupil position	males	3.0 %	1.0
eye morphology	pupil position	both	4.0 %	1.00
eye morphology	pupil shape	females	3.0 %	1.00
eye morphology	pupil shape	males	2.0 %	1.0
eye morphology	pupil shape	both	3.0 %	1.00
eye morphology	retina	females	10.0 %	1.0
eye morphology	retina	males	19.0 %	0.315
eye morphology	retina	both	8.0 %	0.589
eye morphology	retinal blood vessels	females	4.0 %	1.0
eye morphology	retinal blood vessels	males	2.0 %	1.0
eye morphology	retinal blood vessels	both	3.0 %	1.0
eye morphology	retinal blood vessels pattern	females	5.0 %	1.0
eye morphology	retinal blood vessels pattern	males	2.0 %	1.0
eye morphology	retinal blood vessels pattern	both	4.0 %	1.00
eye morphology	retinal blood vessels structure	females	4.0 %	1.00
eye morphology	retinal blood vessels structure	males	2.0 %	1.0
eye morphology	retinal blood vessels structure	both	3.0 %	1.00
eye morphology	retinal pigmentation	females	12.0 %	1.0
eye morphology	retinal pigmentation	males	10.0 %	0.432
eye morphology	retinal pigmentation	both	7.0 %	0.738
eye morphology	retinal structure	females	4.0 %	1.00
eye morphology	retinal structure	males	2.0 %	1.0
eye morphology	retinal structure	both	3.0 %	1.00
eye morphology	synechia	females	4.0 %	1.0
eye morphology	synechia	males	2.0 %	1.0
eye morphology	synechia	both	3.0 %	1.00
eye morphology	vitreous	females	4.0 %	1.00
eye morphology	vitreous	males	2.0 %	1.0
eye morphology	vitreous	both	3.0 %	1.00
SHIRPA	activity body position	females	1.0 %	1.0
SHIRPA	activity body position	males	2.0 %	1.0
SHIRPA	activity body position	both	1.0 %	1.00
SHIRPA	aggression	females	0.0 %	1.00
SHIRPA	aggression	males	1.0 %	1.0
SHIRPA	aggression	both	1.0 %	1.0
SHIRPA	body length	females	0.0 %	1.0
SHIRPA	body length	males	0.0 %	1.00
SHIRPA	body length	both	0.0 %	1.00
SHIRPA	body position	females	0.0 %	1.0
SHIRPA	body position	males	1.0 %	1.0
SHIRPA	body position	both	0.0 %	1.0
SHIRPA	body thickness	females	1.0 %	1.0
SHIRPA	body thickness	males	0.0 %	1.0
SHIRPA	body thickness	both	0.0 %	1.0
SHIRPA	coat color abdomen	females	3.0 %	1.00
SHIRPA	coat color abdomen	males	4.0 %	1.0
SHIRPA	coat color abdomen	both	4.0 %	1.0
SHIRPA	coat color back	females	0.0 %	1.0
SHIRPA	coat color back	males	0.0 %	1.00
SHIRPA	coat color back	both	0.0 %	1.00
SHIRPA	coat color head	females	0.0 %	1.0
SHIRPA	coat color head	males	0.0 %	1.00
SHIRPA	coat color head	both	0.0 %	1.0
SHIRPA	coat color pattern abdomen	females	1.0 %	1.0
SHIRPA	coat color pattern abdomen	males	1.0 %	1.0
SHIRPA	coat color pattern abdomen	both	1.0 %	1.0
SHIRPA	coat color pattern back	females	0.0 %	1.0
SHIRPA	coat color pattern back	males	0.0 %	1.00
SHIRPA	coat color pattern back	both	0.0 %	1.0
SHIRPA	coat color pattern head	females	0.0 %	1.0
SHIRPA	coat color pattern head	males	0.0 %	1.0
SHIRPA	coat color pattern head	both	0.0 %	1.00
SHIRPA	coat hair abdomen texture appearance	females	2.0 %	1.0
SHIRPA	coat hair abdomen texture appearance	males	2.0 %	1.0
SHIRPA	coat hair abdomen texture appearance	both	2.0 %	1.0
SHIRPA	coat hair back texture appearance	females	0.0 %	1.0
SHIRPA	coat hair back texture appearance	males	0.0 %	1.0
SHIRPA	coat hair back texture appearance	both	0.0 %	1.0
SHIRPA	coat hair distribution abdomen	females	0.0 %	1.0
SHIRPA	coat hair distribution abdomen	males	1.0 %	1.00
SHIRPA	coat hair distribution abdomen	both	1.0 %	1.00
SHIRPA	coat hair distribution back	females	25.0 %	0.000157
SHIRPA	coat hair distribution back	males	0.0 %	1.0
SHIRPA	coat hair distribution back	both	12.0 %	0.000625
SHIRPA	coat hair distribution head	females	1.0 %	1.00
SHIRPA	coat hair distribution head	males	1.0 %	1.0
SHIRPA	coat hair distribution head	both	1.0 %	1.0
SHIRPA	coat hair head texture appearance	females	0.0 %	1.00
SHIRPA	coat hair head texture appearance	males	0.0 %	1.0
SHIRPA	coat hair head texture appearance	both	0.0 %	1.0
SHIRPA	contact righting	females	5.0 %	1.0
SHIRPA	contact righting	males	5.0 %	1.00
SHIRPA	contact righting	both	5.0 %	1.00
SHIRPA	ear morphology	females	0.0 %	1.0
SHIRPA	ear morphology	males	0.0 %	1.0
SHIRPA	ear morphology	both	0.0 %	1.0
SHIRPA	fat distribution	females	0.0 %	1.0
SHIRPA	fat distribution	males	0.0 %	1.0
SHIRPA	fat distribution	both	0.0 %	1.00
SHIRPA	forelimb digit number	females	0.0 %	1.00
SHIRPA	forelimb digit number	males	0.0 %	1.0
SHIRPA	forelimb digit number	both	0.0 %	1.00
SHIRPA	forelimb digit position	females	0.0 %	1.0
SHIRPA	forelimb digit position	males	0.0 %	1.0
SHIRPA	forelimb digit position	both	0.0 %	1.0
SHIRPA	forelimb digit shape	females	0.0 %	1.0
SHIRPA	forelimb digit shape	males	0.0 %	1.0
SHIRPA	forelimb digit shape	both	0.0 %	1.0
SHIRPA	forelimb digit size	females	0.0 %	1.0
SHIRPA	forelimb digit size	males	0.0 %	1.0
SHIRPA	forelimb digit size	both	0.0 %	1.0
SHIRPA	forelimb footpads	females	0.0 %	1.0
SHIRPA	forelimb footpads	males	0.0 %	1.0
SHIRPA	forelimb footpads	both	0.0 %	1.0
SHIRPA	forelimb nail length	females	0.0 %	1.0
SHIRPA	forelimb nail length	males	0.0 %	1.0
SHIRPA	forelimb nail length	both	0.0 %	1.0
SHIRPA	forelimb nail number	females	0.0 %	1.0
SHIRPA	forelimb nail number	males	0.0 %	1.0
SHIRPA	forelimb nail number	both	0.0 %	1.0
SHIRPA	forelimb nail position	females	0.0 %	1.0
SHIRPA	forelimb nail position	males	0.0 %	1.0
SHIRPA	forelimb nail position	both	0.0 %	1.0
SHIRPA	forelimb nail shape	females	0.0 %	1.0
SHIRPA	forelimb nail shape	males	0.0 %	1.0
SHIRPA	forelimb nail shape	both	0.0 %	1.0
SHIRPA	forelimbs position	females	0.0 %	1.0
SHIRPA	forelimbs position	males	0.0 %	1.0
SHIRPA	forelimbs position	both	0.0 %	1.0
SHIRPA	forelimbs shape	females	0.0 %	1.0
SHIRPA	forelimbs shape	males	0.0 %	1.0
SHIRPA	forelimbs shape	both	0.0 %	1.0
SHIRPA	forelimbs size	females	0.0 %	1.0
SHIRPA	forelimbs size	males	0.0 %	1.0
SHIRPA	forelimbs size	both	0.0 %	1.0
SHIRPA	forepaw position	females	0.0 %	1.0
SHIRPA	forepaw position	males	0.0 %	1.0
SHIRPA	forepaw position	both	0.0 %	1.0
SHIRPA	forepaw shape	females	0.0 %	1.0
SHIRPA	forepaw shape	males	0.0 %	1.0
SHIRPA	forepaw shape	both	0.0 %	1.0
SHIRPA	forepaw size	females	0.0 %	1.0
SHIRPA	forepaw size	males	0.0 %	1.0
SHIRPA	forepaw size	both	0.0 %	1.0
SHIRPA	gait (fluidity)	females	0.0 %	1.0
SHIRPA	gait (fluidity)	males	0.0 %	1.00
SHIRPA	gait (fluidity)	both	0.0 %	1.00
SHIRPA	genitalia morphology	females	0.0 %	1.00
SHIRPA	genitalia morphology	males	0.0 %	1.0
SHIRPA	genitalia morphology	both	0.0 %	1.00
SHIRPA	genitalia presence	females	0.0 %	1.0
SHIRPA	genitalia presence	males	0.0 %	1.0
SHIRPA	genitalia presence	both	0.0 %	1.0
SHIRPA	genitalia size	females	0.0 %	1.0
SHIRPA	genitalia size	males	0.0 %	1.0
SHIRPA	genitalia size	both	0.0 %	1.0
SHIRPA	head bobbing	females	0.0 %	1.0
SHIRPA	head bobbing	males	0.0 %	1.0
SHIRPA	head bobbing	both	0.0 %	1.0
SHIRPA	head morphology	females	0.0 %	1.0
SHIRPA	head morphology	males	0.0 %	1.00
SHIRPA	head morphology	both	0.0 %	1.0
SHIRPA	head size	females	0.0 %	1.0
SHIRPA	head size	males	0.0 %	1.0
SHIRPA	head size	both	0.0 %	1.00
SHIRPA	hindlimb digit number	females	1.0 %	1.00
SHIRPA	hindlimb digit number	males	0.0 %	1.0
SHIRPA	hindlimb digit number	both	0.0 %	1.00
SHIRPA	hindlimb digit position	females	0.0 %	1.0
SHIRPA	hindlimb digit position	males	0.0 %	1.0
SHIRPA	hindlimb digit position	both	0.0 %	1.0
SHIRPA	hindlimb digit shape	females	0.0 %	1.0
SHIRPA	hindlimb digit shape	males	0.0 %	1.0
SHIRPA	hindlimb digit shape	both	0.0 %	1.0
SHIRPA	hindlimb digit size	females	0.0 %	1.00
SHIRPA	hindlimb digit size	males	0.0 %	1.0
SHIRPA	hindlimb digit size	both	0.0 %	1.00
SHIRPA	hindlimb nail length	females	0.0 %	1.0
SHIRPA	hindlimb nail length	males	0.0 %	1.0
SHIRPA	hindlimb nail length	both	0.0 %	1.00
SHIRPA	hindlimb nail number	females	0.0 %	1.0
SHIRPA	hindlimb nail number	males	1.0 %	1.0
SHIRPA	hindlimb nail number	both	0.0 %	1.00
SHIRPA	hindlimb nail position	females	0.0 %	1.0
SHIRPA	hindlimb nail position	males	0.0 %	1.0
SHIRPA	hindlimb nail position	both	0.0 %	1.0
SHIRPA	hindlimb nail shape	females	0.0 %	1.0
SHIRPA	hindlimb nail shape	males	0.0 %	1.0
SHIRPA	hindlimb nail shape	both	0.0 %	1.0
SHIRPA	hindlimbs footpads	females	0.0 %	1.0
SHIRPA	hindlimbs footpads	males	0.0 %	1.0
SHIRPA	hindlimbs footpads	both	0.0 %	1.0
SHIRPA	hindlimbs position	females	0.0 %	1.0
SHIRPA	hindlimbs position	males	0.0 %	1.0
SHIRPA	hindlimbs position	both	0.0 %	1.0
SHIRPA	hindlimbs shape	females	0.0 %	1.0
SHIRPA	hindlimbs shape	males	0.0 %	1.0
SHIRPA	hindlimbs shape	both	0.0 %	1.0
SHIRPA	hindlimbs size	females	0.0 %	1.0
SHIRPA	hindlimbs size	males	0.0 %	1.0
SHIRPA	hindlimbs size	both	0.0 %	1.0
SHIRPA	hindpaw position	females	0.0 %	1.0
SHIRPA	hindpaw position	males	0.0 %	1.0
SHIRPA	hindpaw position	both	0.0 %	1.0
SHIRPA	hindpaw shape	females	0.0 %	1.0
SHIRPA	hindpaw shape	males	0.0 %	1.0
SHIRPA	hindpaw shape	both	0.0 %	1.0
SHIRPA	hindpaw size	females	0.0 %	1.0
SHIRPA	hindpaw size	males	0.0 %	1.0
SHIRPA	hindpaw size	both	0.0 %	1.0
SHIRPA	limb grasp	females	9.0 %	1.00
SHIRPA	limb grasp	males	6.0 %	1.0
SHIRPA	limb grasp	both	7.0 %	0.624
SHIRPA	lower lip morphology	females	0.0 %	1.0
SHIRPA	lower lip morphology	males	0.0 %	1.0
SHIRPA	lower lip morphology	both	0.0 %	1.0
SHIRPA	lower teeth appearance	females	0.0 %	1.0
SHIRPA	lower teeth appearance	males	0.0 %	1.00
SHIRPA	lower teeth appearance	both	0.0 %	1.00
SHIRPA	mouth morphology	females	0.0 %	1.0
SHIRPA	mouth morphology	males	0.0 %	1.00
SHIRPA	mouth morphology	both	0.0 %	1.00
SHIRPA	salivation	females	0.0 %	1.0
SHIRPA	salivation	males	0.0 %	1.0
SHIRPA	salivation	both	0.0 %	1.0
SHIRPA	skin color back paws	females	0.0 %	1.0
SHIRPA	skin color back paws	males	0.0 %	1.0
SHIRPA	skin color back paws	both	0.0 %	1.0
SHIRPA	skin color ear	females	0.0 %	1.0
SHIRPA	skin color ear	males	0.0 %	1.0
SHIRPA	skin color ear	both	0.0 %	1.0
SHIRPA	skin color front paws	females	0.0 %	1.0
SHIRPA	skin color front paws	males	0.0 %	1.0
SHIRPA	skin color front paws	both	0.0 %	1.0
SHIRPA	skin color snout	females	0.0 %	1.0
SHIRPA	skin color snout	males	0.0 %	1.0
SHIRPA	skin color snout	both	0.0 %	1.0
SHIRPA	skin color tail	females	0.0 %	1.0
SHIRPA	skin color tail	males	0.0 %	1.0
SHIRPA	skin color tail	both	0.0 %	1.0
SHIRPA	skin color whole body	females	0.0 %	1.0
SHIRPA	skin color whole body	males	0.0 %	1.0
SHIRPA	skin color whole body	both	0.0 %	1.0
SHIRPA	skin texture back paw	females	0.0 %	1.0
SHIRPA	skin texture back paw	males	0.0 %	1.0
SHIRPA	skin texture back paw	both	0.0 %	1.0
SHIRPA	skin texture ear	females	0.0 %	1.0
SHIRPA	skin texture ear	males	0.0 %	1.0
SHIRPA	skin texture ear	both	0.0 %	1.0
SHIRPA	skin texture front paws	females	0.0 %	1.0
SHIRPA	skin texture front paws	males	0.0 %	1.0
SHIRPA	skin texture front paws	both	0.0 %	1.0
SHIRPA	skin texture snout	females	0.0 %	1.0
SHIRPA	skin texture snout	males	0.0 %	1.0
SHIRPA	skin texture snout	both	0.0 %	1.0
SHIRPA	skin texture tail	females	0.0 %	1.0
SHIRPA	skin texture tail	males	0.0 %	1.0
SHIRPA	skin texture tail	both	0.0 %	1.0
SHIRPA	skin texture whole body	females	0.0 %	1.0
SHIRPA	skin texture whole body	males	0.0 %	1.00
SHIRPA	skin texture whole body	both	0.0 %	1.00
SHIRPA	snout size	females	0.0 %	1.0
SHIRPA	snout size	males	1.0 %	1.0
SHIRPA	snout size	both	0.0 %	1.0
SHIRPA	startle response	females	0.0 %	1.00
SHIRPA	startle response	males	0.0 %	1.00
SHIRPA	startle response	both	0.0 %	1.00
SHIRPA	tail curvature	females	0.0 %	1.00
SHIRPA	tail curvature	males	0.0 %	1.0
SHIRPA	tail curvature	both	0.0 %	1.0
SHIRPA	tail elevation	females	1.0 %	1.00
SHIRPA	tail elevation	males	2.0 %	1.0
SHIRPA	tail elevation	both	1.0 %	1.0
SHIRPA	tail length	females	0.0 %	1.0
SHIRPA	tail length	males	0.0 %	1.0
SHIRPA	tail length	both	0.0 %	1.00
SHIRPA	tail morphology	females	0.0 %	1.00
SHIRPA	tail morphology	males	0.0 %	1.0
SHIRPA	tail morphology	both	0.0 %	1.00
SHIRPA	tail presence	females	0.0 %	1.0
SHIRPA	tail presence	males	0.0 %	1.0
SHIRPA	tail presence	both	0.0 %	1.0
SHIRPA	tail shape	females	0.0 %	1.0
SHIRPA	tail shape	males	0.0 %	1.0
SHIRPA	tail shape	both	0.0 %	1.00
SHIRPA	tail thickness	females	0.0 %	1.0
SHIRPA	tail thickness	males	0.0 %	1.0
SHIRPA	tail thickness	both	0.0 %	1.0
SHIRPA	teeth presence	females	0.0 %	1.0
SHIRPA	teeth presence	males	0.0 %	1.00
SHIRPA	teeth presence	both	0.0 %	1.00
SHIRPA	transfer arousal	females	1.0 %	1.0
SHIRPA	transfer arousal	males	2.0 %	1.00
SHIRPA	transfer arousal	both	1.0 %	1.0
SHIRPA	tremor	females	0.0 %	1.0
SHIRPA	tremor	males	0.0 %	1.0
SHIRPA	tremor	both	0.0 %	1.00
SHIRPA	trunk curl	females	0.0 %	1.00
SHIRPA	trunk curl	males	0.0 %	1.0
SHIRPA	trunk curl	both	0.0 %	1.0
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	females	0.0 %	1.0
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	males	0.0 %	1.0
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	both	0.0 %	1.00
SHIRPA	upper lip morphology	females	0.0 %	1.0
SHIRPA	upper lip morphology	males	0.0 %	1.0
SHIRPA	upper lip morphology	both	0.0 %	1.0
SHIRPA	upper teeth appearance	females	0.0 %	1.0
SHIRPA	upper teeth appearance	males	0.0 %	1.0
SHIRPA	upper teeth appearance	both	0.0 %	1.00
SHIRPA	vibrissae appearance	females	2.0 %	1.0
SHIRPA	vibrissae appearance	males	1.0 %	1.0
SHIRPA	vibrissae appearance	both	1.0 %	1.0
SHIRPA	vibrissae presence	females	2.0 %	1.00
SHIRPA	vibrissae presence	males	1.0 %	1.0
SHIRPA	vibrissae presence	both	2.0 %	1.0
SHIRPA	vocalization	females	2.0 %	1.00
SHIRPA	vocalization	males	2.0 %	1.0
SHIRPA	vocalization	both	2.0 %	1.00

GENOTYPE CORRELATION PLOT

Correlate Slc35c2^{tm1.1(KOMP)Vlcg} -/- with genotype: