MPD: JaxKOMP-EAP genotype: Psd4<sup>tm1.1(KOMP)Vlcg</sup>/2J -/-

JaxKOMP-EAP effect sizes: Psd4^{tm1.1(KOMP)Vlcg}/2J -/- Gene Psd4

MULTIPLE (NUMERIC) TRAIT PROFILE PLOT — Early Adult Phenotyping study (EAP)

Procedure	JaxKOMP-EAP Trait	Trait Effect	Trait Effect SE	Trait Effect RankZ	Adjusted p-value	Unadjusted p-value
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 6 kHz pip	2.1869	2.1834	0.41812	0.772	0.373
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 12 kHz pip	0.90479	5.3964	0.20476	0.961	0.875
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 18 kHz pip	1.1260	4.1288	0.087453	0.937	0.799
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 24 kHz pip	4.5926	10.343	0.61259	0.881	0.680
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 30 kHz pip	5.1231	13.330	0.79383	0.887	0.720
body composition	body length	0.017735	0.041282	0.44635	0.847	0.669
body composition	body weight (at time of DXA)	-0.49991	0.52234	-0.28703	0.563	0.342
body composition	bone area, whole body scan, head excluded	0.20563	0.12339	1.0610	0.322	0.100
body composition	bone mineral content of whole body scan, head excluded	0.010565	0.0092467	0.75197	0.542	0.257
body composition	bone mineral content to body weight ratio	0.00027902	0.00039825	0.53982	0.723	0.486
body composition	bone mineral density of whole body scan, head excluded	0.00012368	0.00046096	0.16397	0.904	0.789
body composition	fat tissue mass of whole body scan, head excluded	-0.42257	0.27761	-0.78499	0.351	0.133
body composition	fat tissue mass to body weight ratio	-0.015521	0.0099104	-0.68136	0.315	0.122
body composition	lean tissue mass of whole body scan, head excluded	0.58749	0.24579	0.97618	0.152	0.0197
body composition	lean tissue mass to body weight ratio	0.019290	0.0089702	0.96054	0.171	0.0352
body composition	percent fat, whole body scan, head excluded	-1.5978	0.96322	-0.75560	0.288	0.102
body composition	ratio of soft-tissue attenuation coefficients	0.0017842	0.0010792	0.75943	0.290	0.103
body composition	tissue area	-0.026398	0.17899	0.098566	0.963	0.883
body composition	total tissue mass, whole body scan, head excluded	0.15767	0.17639	0.15075	0.626	0.375
clinical blood chemistry	alanine transaminase (plasma ALT)	3.1818	4.3134	0.27771	0.786	0.467
clinical blood chemistry	albumin (plasma Alb)	-0.69143	0.42627	-0.86129	0.419	0.117
clinical blood chemistry	alkaline phosphatase (plasma ALP)	-2.2484	4.7544	-0.92276	0.813	0.640
clinical blood chemistry	aspartate transaminase (plasma AST)	1.5120	12.828	0.079479	0.980	0.907
clinical blood chemistry	aspartate transaminase to alanine transaminase ratio (plasma AST:ALT)	0.14172	0.31279	0.47264	0.891	0.654
clinical blood chemistry	blood urea nitrogen (BUN)	-0.41378	1.1888	-0.19397	0.869	0.731
clinical blood chemistry	calcium (plasma Ca)	0.052958	0.087923	0.71751	0.743	0.552
clinical blood chemistry	creatinine (plasma)	-0.0053966	0.025089	-0.0010214	0.911	0.831
clinical blood chemistry	glucose (plasma GLU, no fast)	-21.046	11.032	-0.50078	0.194	0.0675
clinical blood chemistry	HDL cholesterol (plasma HDL)	4.9727	3.7884	0.84122	0.504	0.201
clinical blood chemistry	HDL cholesterol to total cholesterol ratio	-0.0041486	0.015453	-0.40124	0.940	0.790
clinical blood chemistry	phosphorus (plasma phosphate)	0.41121	0.28455	0.55191	0.423	0.160
clinical blood chemistry	total bilirubin (plasma TBIL)	-0.0014358	0.011557	-0.099521	0.970	0.902
clinical blood chemistry	total cholesterol (plasma CHOL, no fast)	4.9859	4.5169	0.63529	0.593	0.280
clinical blood chemistry	total protein (plasma TP)	-0.37038	0.56878	-0.35870	0.741	0.521
clinical blood chemistry	triglyceride (plasma TG, no fast)	11.250	7.4188	0.82623	0.418	0.142
EKG	duration of PQ interval	-0.022061	0.71281	0.12729	0.991	0.976
EKG	duration of PR interval	-0.25962	0.75182	-0.16394	0.938	0.733
EKG	duration of QRS interval	-0.40550	0.39105	-1.2216	0.885	0.309
EKG	duration of QT interval	-1.3885	0.73035	-1.0991	0.573	0.0680
EKG	duration of QTC interval, calculated by dividing QT interval by square root of preceding RR interval	-1.1439	0.72217	-1.1178	0.702	0.125
EKG	duration of RR interval	-1.5679	1.3855	-0.56933	0.690	0.268
EKG	duration of ST interval	-0.99473	0.77889	-0.74713	0.716	0.212
EKG	heart rate coefficient of variation (signal intensity)	-1.2636	0.99411	-0.98800	0.841	0.215
EKG	heart rate variability, mean of differences between sequential beats; beats per min	-8.4553	6.7276	-0.94304	0.853	0.220
EKG	heart rate, beats per min	11.898	10.559	0.45818	0.678	0.270
EKG	mean R amplitude, mean amplitude of signal measured from isoelectric line to peak of QRS	0.091580	0.080637	0.61186	0.645	0.266
EKG	mean SR amplitude, mean amplitude of signal measured from signal minimum line to peak of QRS	0.12627	0.10960	0.62162	0.626	0.259
EKG	number of signals	2.9099	4.1846	0.53646	0.877	0.493
EKG	proportion of number pairs of successive beat-to-beat intervals that exceed 50 ms	-5.9498	5.4357	-1.0712	0.817	0.283
EKG	QT dispersion, measured as inter-lead variability of QT intervals	0.63747	2.6732	0.23798	0.977	0.813
EKG	QTc dispersion, calculated as rate-corrected QT dispersion	1.3492	2.4880	0.36672	0.945	0.592
EKG	root mean square of successive differences of neighboring RR intervals	-1.6144	1.1840	-0.77676	0.843	0.184
glucose tolerance test	amount glucose injected	1.2437	3.0556	0.71608	0.899	0.688
glucose tolerance test	plasma glucose, 0min	-11.481	10.790	-1.2003	0.517	0.298
glucose tolerance test	plasma glucose, 15min	-58.823	30.967	-1.4510	0.312	0.0696
glucose tolerance test	plasma glucose, 30min	-46.539	29.120	-1.2290	0.440	0.123
glucose tolerance test	plasma glucose, 60min	-36.802	26.548	-1.4054	0.492	0.178
glucose tolerance test	plasma glucose, 120min	-32.210	21.517	-2.0597	0.453	0.147
grip strength	body weight (at time of grip strength test)	-0.32356	0.39897	-0.098801	0.616	0.423
grip strength	forelimb and hindlimb grip strength (mean of trials), average	-37.553	7.8242	-2.1111	0.00120	0.0000356
grip strength	forelimb and hindlimb grip strength (mean of trials), average normalized to bw	-2.0215	0.39572	-2.4908	0.00101	0.0000157
grip strength	forelimb and hindlimb grip strength by trial, trial1	-36.398	9.5599	-1.9516	0.0167	0.000600
grip strength	forelimb and hindlimb grip strength by trial, trial2	-31.647	9.4398	-1.7183	0.0327	0.00207
grip strength	forelimb and hindlimb grip strength by trial, trial3	-43.989	10.004	-2.3106	0.00522	0.000113
grip strength	forelimb grip strength (mean of trials), average	-18.220	6.1733	-1.7928	0.0545	0.00588
grip strength	forelimb grip strength (mean of trials), average normalized to bw	-0.91891	0.29232	-1.8001	0.0439	0.00359
grip strength	forelimb grip strength by trial, trial1	-16.095	7.3666	-1.4664	0.254	0.0363
grip strength	forelimb grip strength by trial, trial2	-23.802	6.2821	-2.0723	0.0205	0.000655
grip strength	forelimb grip strength by trial, trial3	-11.444	7.0846	-0.95513	0.393	0.116
heart weight	heart weight, normalized to body weight	0.077257	0.10391	-0.16493	0.663	0.463
heart weight	heart weight, weight	2.8129	2.8508	-0.0074321	0.547	0.332
hematology	basophil differential (percent of total WBC)	0.15000	0.045815	1.7081	0.133	0.00300
hematology	calculated hemoglobin (cHGB)	0.021526	0.17878	-0.21725	0.960	0.905
hematology	eosinophil differential (percent of total WBC)	0.024776	0.24461	0.13925	0.970	0.920
hematology	hematocrit (HCT)	-0.18087	0.48826	-0.54205	0.860	0.714
hematology	hemoglobin concentration distribution width (HDW)	0.018489	0.021003	0.49786	0.688	0.387
hematology	large unstained cells (percent of total WBC)	-0.10069	0.14512	-0.69812	0.784	0.494
hematology	lymphocyte differential (percent of total WBC)	1.6986	1.4330	0.61972	0.501	0.247
hematology	mean corpuscular hemoglobin (CHr)	0.045175	0.052524	0.39061	0.638	0.398
hematology	mean platelet volume (MPV)	0.43792	0.13450	1.6006	0.0236	0.00313
hematology	mean RBC corpuscular hemoglobin (MCH)	0.69434	0.83702	1.7974	0.750	0.414
hematology	mean RBC corpuscular hemoglobin concentration (MCHC)	1.3758	1.9553	1.8123	0.793	0.488
hematology	mean RBC corpuscular volume (MCV)	-0.0099314	0.29309	-0.010934	0.988	0.973
hematology	measured hemoglobin (mHGB)	0.57872	0.85267	1.2430	0.736	0.503
hematology	monocyte differential (percent of total WBC)	-0.065228	0.13223	0.0	0.859	0.626
hematology	neutrophil differential (percent of total WBC)	-1.6431	1.3719	-0.72958	0.492	0.242
hematology	platelet count (PLT; units per volume x 10³)	55.157	46.868	0.77308	0.624	0.250
hematology	RBC corpuscular distribution width (RDW)	0.16818	0.14214	0.56687	0.514	0.247
hematology	RBC corpuscular hemoglobin concentration mean (CHCM)	0.11811	0.24721	0.29856	0.826	0.637
hematology	red blood cell count (RBC; per volume x 10⁶)	-0.036738	0.11611	-0.50192	0.889	0.754
hematology	reticulocyte count (Retic; units per volume x 10⁹)	17.768	12.170	0.81453	0.543	0.157
hematology	reticulocyte differential (percent of total RBC)	0.21182	0.12873	1.0500	0.456	0.112
hematology	white blood cell count (WBC; units per volume x 10³)	0.80205	0.66078	0.71362	0.443	0.236
holeboard	number of hole pokes by individual hole number, 20 min test, 1	0.35049	0.65059	0.40128	0.873	0.592
holeboard	number of hole pokes by individual hole number, 20 min test, 2	-0.12140	0.35980	-0.061650	0.945	0.737
holeboard	number of hole pokes by individual hole number, 20 min test, 3	0.099262	0.39888	0.25509	0.950	0.804
holeboard	number of hole pokes by individual hole number, 20 min test, 4	0.35606	0.46923	0.43258	0.824	0.451
holeboard	number of hole pokes by individual hole number, 20 min test, 5	-0.24535	0.33119	-0.27958	0.854	0.462
holeboard	number of hole pokes by individual hole number, 20 min test, 6	0.049701	0.20955	0.19350	0.969	0.813
holeboard	number of hole pokes by individual hole number, 20 min test, 7	-0.19461	0.22641	-0.56538	0.885	0.394
holeboard	number of hole pokes by individual hole number, 20 min test, 8	-0.36519	0.39851	-0.50417	0.807	0.364
holeboard	number of hole pokes by individual hole number, 20 min test, 9	0.14910	0.34280	0.38241	0.938	0.665
holeboard	number of hole pokes by individual hole number, 20 min test, 10	0.072156	0.25361	0.25999	0.954	0.777
holeboard	number of hole pokes by individual hole number, 20 min test, 11	0.025749	0.26141	0.069309	0.987	0.922
holeboard	number of hole pokes by individual hole number, 20 min test, 12	-0.25928	0.39673	-0.35839	0.869	0.516
holeboard	number of hole pokes by individual hole number, 20 min test, 13	-0.46619	0.60116	-0.39460	0.784	0.442
holeboard	number of hole pokes by individual hole number, 20 min test, 14	-0.30139	0.46703	-0.38187	0.848	0.522
holeboard	number of hole pokes by individual hole number, 20 min test, 15	-0.70948	0.39659	-1.0448	0.546	0.0795
holeboard	number of hole pokes by individual hole number, 20 min test, 16	-1.3511	0.91032	-1.1727	0.572	0.144
holeboard	total number of hole pokes, 20 min test	-2.9578	3.2374	-0.31199	0.644	0.365
light / dark	fecal boli count, 20 min test	-0.14007	0.68899	-0.11177	0.936	0.840
light / dark	latency to enter dark zone, 20 min test	65.921	36.407	1.0601	0.489	0.0752
light / dark	number of transitions between light and dark zones, 20 min test	-8.4639	6.2562	-0.74315	0.503	0.181
light / dark	percentage of total time in dark zone, 20 min test	7.5588	4.1479	1.5078	0.385	0.0734
light / dark	percentage of total time in light zone, 20 min test	-7.5588	4.1479	-1.5120	0.383	0.0734
light / dark	time mobile in dark zone, 20 min test	-1.8880	12.129	-0.21804	0.953	0.877
light / dark	time mobile in light zone, 20 min test	-5.2671	10.321	-0.63347	0.813	0.612
light / dark	time spent in dark zone, 20 min test	22.672	53.765	0.54499	0.898	0.675
light / dark	time spent in light zone, 20 min test	-22.672	53.765	-0.54499	0.898	0.675
open field	average speed in center of arena, 20 min test	0.061337	0.32369	0.018126	0.954	0.850
open field	average speed in periphery of arena, 20 min test	0.27540	0.14159	0.55406	0.177	0.0562
open field	distance traveled habituation ratio, 20 min test	-6.0317	7.1269	-0.48641	0.703	0.401
open field	distance traveled in center of arena, 20 min test	132.98	80.012	0.49702	0.301	0.101
open field	distance traveled in periphery of arena, 20 min test	217.55	138.80	0.40484	0.323	0.122
open field	distance traveled slope, 20 min test	-7.3744	7.0168	-0.63416	0.623	0.297
open field	distance traveled, 20 min test, 1st 5min	132.38	63.801	0.68931	0.173	0.0421
open field	distance traveled, 20 min test, 2nd 5min	101.87	56.446	0.61134	0.247	0.0759
open field	distance traveled, 20 min test, 3rd 5min	35.063	51.457	-0.043648	0.721	0.498
open field	distance traveled, 20 min test, 4th 5min	82.570	46.924	0.45343	0.261	0.0833
open field	number of clockwise revolution episodes, 20 min test	0.049742	1.2681	-0.37824	0.988	0.969
open field	number of counter-clockwise revolution episodes, 20 min test	1.0723	1.2340	0.15842	0.665	0.388
open field	number of fecal boli, 20 min test	-0.39641	0.87124	-0.024537	0.847	0.651
open field	number of rears in 5 min bins, 20 min test, 1st 5min	0.022174	2.3142	-0.20151	0.998	0.992
open field	number of rears in 5 min bins, 20 min test, 2nd 5min	4.8211	2.8508	0.92574	0.335	0.0957
open field	number of rears in 5 min bins, 20 min test, 3rd 5min	1.5968	2.6296	0.066508	0.761	0.546
open field	number of rears in 5 min bins, 20 min test, 4th 5min	1.6970	3.0238	0.034243	0.782	0.577
open field	percentage of total time in center of arena, 20 min test	1.9822	2.8698	0.24753	0.768	0.492
open field	percentage of total time in center of arena, slope, 20 min test	0.22496	1.4289	0.23509	0.965	0.875
open field	percentage of total time in center, habituation ratio, 20 min test	0.33252	1.4596	0.29069	0.957	0.821
open field	percentage of total time in corners of arena, 20 min test	-3.5353	3.9464	-0.32164	0.673	0.374
open field	percentage of total time in corners, habituation ratio, 20 min test	-0.16500	1.6756	-0.37443	0.989	0.922
open field	percentage of total time in corners, slope, 20 min test	0.32589	1.6260	-0.12586	0.967	0.842
open field	permanence time in center of arena, 20 min test	23.779	34.438	0.24614	0.768	0.492
open field	permanence time in corners of arena, 20 min test	-42.416	47.356	-0.32164	0.673	0.374
open field	permanence time in periphery of arena, 20 min test	-23.750	34.439	-0.24614	0.768	0.493
open field	total distance traveled, 20 min test	360.40	183.67	0.54158	0.177	0.0542
open field	total number of rears, 20 min test	8.1544	9.5527	0.22544	0.644	0.397
open field	whole arena average speed, 20 min test	0.29975	0.15305	0.54002	0.178	0.0546
open field	whole arena resting time, 20 min test	-29.694	18.578	-0.28789	0.276	0.115
open field	whole arena time spent mobile, 20 min test	29.754	18.575	0.54158	0.278	0.114
open field	whole arena time spent vertical, 20 min test	16.185	9.5451	1.1724	0.350	0.0950
SHIRPA	locomotor activity (number of squares in the arena the mouse moves into with all four paws in first 30 s of test)	0.19827	1.6211	0.29374	0.974	0.903
startle / PPI	average baseline movement during background noise	-0.51791	1.5928	-0.31256	0.952	0.747
startle / PPI	average of each corrected maximum percent pre-pulse inhibition value	0.70571	0.45972	2.3917	0.474	0.133
startle / PPI	average of each corrected percent pre-pulse inhibition value	0.022687	0.053498	0.14853	0.871	0.674
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-4.6507	7.6628	-0.45753	0.910	0.547
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	1.0518	6.0861	0.077841	0.959	0.864
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	4.9337	5.3761	0.42817	0.667	0.364
startle / PPI	average startle response to full pulse (120 dB)	-27.442	40.448	-0.34213	0.735	0.501
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-26.608	34.324	-0.35553	0.667	0.443
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-26.594	30.425	-0.37200	0.597	0.387
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-21.167	27.087	-0.33471	0.640	0.439
startle / PPI	average startle response to pre-pulse, 74dB sound pressure level	0.74012	1.2393	0.56618	0.906	0.554
startle / PPI	average startle response to pre-pulse, 78dB sound pressure level	0.71728	1.5352	0.48730	0.936	0.643
startle / PPI	average startle response to pre-pulse, 82dB sound pressure level	2.9816	1.8243	1.0445	0.534	0.110
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-0.043468	0.080984	-0.36001	0.922	0.594
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	0.0095379	0.072043	0.0063122	0.972	0.895
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	0.10122	0.060803	0.60397	0.312	0.104
startle / PPI	corrected average startle response to full pulse (120 dB) minus average baseline movement during background noise	-26.778	40.205	-0.33175	0.736	0.509
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 74dB sound pressure level	-27.247	34.320	-0.36450	0.654	0.432
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 78dB sound pressure level	-27.376	30.881	-0.37200	0.587	0.381
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 82dB sound pressure level	-23.932	27.141	-0.37651	0.593	0.383
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	0.80723	0.68833	2.5035	0.841	0.248
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	1.2218	0.73769	2.8426	0.406	0.105
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	0.092147	0.065870	0.50265	0.422	0.170
startle / PPI	corrected maximum startle response to full pulse (120 dB) minus maximum baseline movement during background noise	-87.647	139.16	-0.28473	0.753	0.532
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 74dB sound pressure level	-136.78	121.31	-0.53197	0.504	0.266
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 78dB sound pressure level	-86.377	113.99	-0.30082	0.651	0.453
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 82dB sound pressure level	-76.748	99.611	-0.29642	0.642	0.446
startle / PPI	maximum baseline movement during background noise	-3.2235	4.0945	-0.89431	0.843	0.436
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-5.4314	8.3634	-0.50632	0.923	0.520
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	1.3374	6.8048	0.032933	0.940	0.845
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	6.2191	6.0191	0.44357	0.594	0.308
startle / PPI	maximum startle response to full pulse (120 dB)	-91.965	139.63	-0.30082	0.737	0.514
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-136.53	121.16	-0.53197	0.509	0.267
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-82.829	112.77	-0.27890	0.666	0.467
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-71.718	99.257	-0.27162	0.665	0.474
startle / PPI	maximum startle response to pre-pulse, 74dB sound pressure level	0.41894	2.9176	0.26291	0.975	0.887
startle / PPI	maximum startle response to pre-pulse, 78dB sound pressure level	3.5039	3.4040	0.87565	0.770	0.310
startle / PPI	maximum startle response to pre-pulse, 82dB sound pressure level	5.2239	3.9685	0.70875	0.578	0.196

MULTIPLE (CATEGORICAL) TRAIT PROFILE PLOT — Early Adult Phenotyping study (EAP)

Procedure	JaxKOMP-EAP Trait	Sex	Trait Effect	P-value
eye morphology	anterior chamber depth	females	1.0 %	1.0
eye morphology	anterior chamber depth	males	0.0 %	1.0
eye morphology	anterior chamber depth	both	1.0 %	1.0
eye morphology	bulging eye	females	1.0 %	1.00
eye morphology	bulging eye	males	0.0 %	1.0
eye morphology	bulging eye	both	1.0 %	1.00
eye morphology	cornea	females	4.0 %	1.00
eye morphology	cornea	males	2.0 %	1.0
eye morphology	cornea	both	3.0 %	1.00
eye morphology	cornea opacity	females	5.0 %	1.00
eye morphology	cornea opacity	males	1.0 %	1.0
eye morphology	cornea opacity	both	3.0 %	1.00
eye morphology	cornea vascularization	females	3.0 %	1.0
eye morphology	cornea vascularization	males	1.0 %	1.0
eye morphology	cornea vascularization	both	2.0 %	1.00
eye morphology	corneal deposits	females	2.0 %	1.00
eye morphology	corneal deposits	males	1.0 %	1.0
eye morphology	corneal deposits	both	1.0 %	1.00
eye morphology	corneal mineralization	females	2.0 %	1.0
eye morphology	corneal mineralization	males	1.0 %	1.0
eye morphology	corneal mineralization	both	1.0 %	1.0
eye morphology	corneal scleralization	females	3.0 %	1.00
eye morphology	corneal scleralization	males	1.0 %	1.0
eye morphology	corneal scleralization	both	2.0 %	1.00
eye morphology	corneal ulcer	females	1.0 %	1.0
eye morphology	corneal ulcer	males	1.0 %	1.0
eye morphology	corneal ulcer	both	1.0 %	1.0
eye morphology	eye closure	females	1.0 %	1.00
eye morphology	eye closure	males	0.0 %	1.0
eye morphology	eye closure	both	1.0 %	1.00
eye morphology	eye hemorrhage or blood presence	females	2.0 %	1.00
eye morphology	eye hemorrhage or blood presence	males	1.0 %	1.0
eye morphology	eye hemorrhage or blood presence	both	1.0 %	1.00
eye morphology	eyelid morphology	females	1.0 %	1.00
eye morphology	eyelid morphology	males	0.0 %	1.0
eye morphology	eyelid morphology	both	1.0 %	1.00
eye morphology	eyes (present, absent)	females	1.0 %	1.00
eye morphology	eyes (present, absent)	males	0.0 %	1.0
eye morphology	eyes (present, absent)	both	0.0 %	1.00
eye morphology	fusion between cornea and lens	females	4.0 %	1.00
eye morphology	fusion between cornea and lens	males	2.0 %	1.0
eye morphology	fusion between cornea and lens	both	3.0 %	1.00
eye morphology	iris pigmentation	females	2.0 %	1.0
eye morphology	iris pigmentation	males	1.0 %	1.0
eye morphology	iris pigmentation	both	2.0 %	1.00
eye morphology	iris transillumination	females	2.0 %	1.00
eye morphology	iris transillumination	males	1.0 %	1.00
eye morphology	iris transillumination	both	1.0 %	1.00
eye morphology	irispupil	females	4.0 %	1.00
eye morphology	irispupil	males	3.0 %	1.0
eye morphology	irispupil	both	3.0 %	1.00
eye morphology	lacrimation	females	3.0 %	1.0
eye morphology	lacrimation	males	14.0 %	0.0518
eye morphology	lacrimation	both	8.0 %	0.0803
eye morphology	lens	females	10.0 %	1.00
eye morphology	lens	males	8.0 %	1.00
eye morphology	lens	both	9.0 %	1.00
eye morphology	lens opacity	females	13.0 %	0.433
eye morphology	lens opacity	males	23.0 %	0.0446
eye morphology	lens opacity	both	16.0 %	0.0683
eye morphology	narrow eye opening	females	2.0 %	1.00
eye morphology	narrow eye opening	males	1.0 %	1.0
eye morphology	narrow eye opening	both	1.0 %	1.00
eye morphology	optic disc	females	17.0 %	0.0199
eye morphology	optic disc	males	2.0 %	1.00
eye morphology	optic disc	both	8.0 %	0.0407
eye morphology	persistence of hyaloid vascular system	females	10.0 %	0.585
eye morphology	persistence of hyaloid vascular system	males	12.0 %	0.299
eye morphology	persistence of hyaloid vascular system	both	11.0 %	0.408
eye morphology	pupil dilation	females	2.0 %	1.0
eye morphology	pupil dilation	males	1.0 %	1.00
eye morphology	pupil dilation	both	2.0 %	1.00
eye morphology	pupil light response	females	2.0 %	1.00
eye morphology	pupil light response	males	1.0 %	1.0
eye morphology	pupil light response	both	2.0 %	1.00
eye morphology	pupil position	females	4.0 %	1.00
eye morphology	pupil position	males	3.0 %	1.0
eye morphology	pupil position	both	4.0 %	1.00
eye morphology	pupil shape	females	3.0 %	1.00
eye morphology	pupil shape	males	2.0 %	1.0
eye morphology	pupil shape	both	3.0 %	1.00
eye morphology	retina	females	10.0 %	1.00
eye morphology	retina	males	8.0 %	0.703
eye morphology	retina	both	5.0 %	0.831
eye morphology	retinal blood vessels	females	4.0 %	1.0
eye morphology	retinal blood vessels	males	2.0 %	1.0
eye morphology	retinal blood vessels	both	3.0 %	1.00
eye morphology	retinal blood vessels pattern	females	5.0 %	1.00
eye morphology	retinal blood vessels pattern	males	2.0 %	1.00
eye morphology	retinal blood vessels pattern	both	4.0 %	1.00
eye morphology	retinal blood vessels structure	females	4.0 %	1.00
eye morphology	retinal blood vessels structure	males	2.0 %	1.0
eye morphology	retinal blood vessels structure	both	3.0 %	1.00
eye morphology	retinal pigmentation	females	12.0 %	1.00
eye morphology	retinal pigmentation	males	11.0 %	0.380
eye morphology	retinal pigmentation	both	5.0 %	0.647
eye morphology	retinal structure	females	4.0 %	1.00
eye morphology	retinal structure	males	2.0 %	1.00
eye morphology	retinal structure	both	3.0 %	1.00
eye morphology	synechia	females	4.0 %	1.0
eye morphology	synechia	males	2.0 %	1.00
eye morphology	synechia	both	3.0 %	1.00
eye morphology	vitreous	females	4.0 %	1.00
eye morphology	vitreous	males	2.0 %	1.0
eye morphology	vitreous	both	3.0 %	1.00
SHIRPA	activity body position	females	1.0 %	1.0
SHIRPA	activity body position	males	2.0 %	1.0
SHIRPA	activity body position	both	1.0 %	1.00
SHIRPA	aggression	females	0.0 %	1.00
SHIRPA	aggression	males	1.0 %	1.0
SHIRPA	aggression	both	1.0 %	1.00
SHIRPA	body length	females	0.0 %	1.0
SHIRPA	body length	males	0.0 %	1.0
SHIRPA	body length	both	0.0 %	1.0
SHIRPA	body position	females	0.0 %	1.0
SHIRPA	body position	males	1.0 %	1.0
SHIRPA	body position	both	0.0 %	1.00
SHIRPA	body thickness	females	1.0 %	1.0
SHIRPA	body thickness	males	0.0 %	1.0
SHIRPA	body thickness	both	0.0 %	1.00
SHIRPA	coat color abdomen	females	3.0 %	1.00
SHIRPA	coat color abdomen	males	4.0 %	1.00
SHIRPA	coat color abdomen	both	4.0 %	1.00
SHIRPA	coat color back	females	0.0 %	1.0
SHIRPA	coat color back	males	0.0 %	1.0
SHIRPA	coat color back	both	0.0 %	1.00
SHIRPA	coat color head	females	0.0 %	1.0
SHIRPA	coat color head	males	0.0 %	1.0
SHIRPA	coat color head	both	0.0 %	1.0
SHIRPA	coat color pattern abdomen	females	1.0 %	1.0
SHIRPA	coat color pattern abdomen	males	1.0 %	1.0
SHIRPA	coat color pattern abdomen	both	1.0 %	1.00
SHIRPA	coat color pattern back	females	0.0 %	1.0
SHIRPA	coat color pattern back	males	0.0 %	1.0
SHIRPA	coat color pattern back	both	0.0 %	1.00
SHIRPA	coat color pattern head	females	0.0 %	1.0
SHIRPA	coat color pattern head	males	0.0 %	1.00
SHIRPA	coat color pattern head	both	0.0 %	1.0
SHIRPA	coat hair abdomen texture appearance	females	2.0 %	1.0
SHIRPA	coat hair abdomen texture appearance	males	2.0 %	1.0
SHIRPA	coat hair abdomen texture appearance	both	2.0 %	1.0
SHIRPA	coat hair back texture appearance	females	0.0 %	1.0
SHIRPA	coat hair back texture appearance	males	0.0 %	1.0
SHIRPA	coat hair back texture appearance	both	0.0 %	1.0
SHIRPA	coat hair distribution abdomen	females	0.0 %	1.0
SHIRPA	coat hair distribution abdomen	males	1.0 %	1.0
SHIRPA	coat hair distribution abdomen	both	1.0 %	1.0
SHIRPA	coat hair distribution back	females	0.0 %	1.0
SHIRPA	coat hair distribution back	males	0.0 %	1.0
SHIRPA	coat hair distribution back	both	0.0 %	1.00
SHIRPA	coat hair distribution head	females	1.0 %	1.00
SHIRPA	coat hair distribution head	males	1.0 %	1.0
SHIRPA	coat hair distribution head	both	1.0 %	1.0
SHIRPA	coat hair head texture appearance	females	0.0 %	1.00
SHIRPA	coat hair head texture appearance	males	0.0 %	1.0
SHIRPA	coat hair head texture appearance	both	0.0 %	1.0
SHIRPA	contact righting	females	5.0 %	1.0
SHIRPA	contact righting	males	5.0 %	1.00
SHIRPA	contact righting	both	5.0 %	1.00
SHIRPA	ear morphology	females	0.0 %	1.0
SHIRPA	ear morphology	males	0.0 %	1.0
SHIRPA	ear morphology	both	0.0 %	1.0
SHIRPA	fat distribution	females	0.0 %	1.0
SHIRPA	fat distribution	males	0.0 %	1.0
SHIRPA	fat distribution	both	0.0 %	1.0
SHIRPA	forelimb digit number	females	0.0 %	1.00
SHIRPA	forelimb digit number	males	0.0 %	1.0
SHIRPA	forelimb digit number	both	0.0 %	1.0
SHIRPA	forelimb digit position	females	0.0 %	1.0
SHIRPA	forelimb digit position	males	0.0 %	1.0
SHIRPA	forelimb digit position	both	0.0 %	1.0
SHIRPA	forelimb digit shape	females	0.0 %	1.0
SHIRPA	forelimb digit shape	males	0.0 %	1.0
SHIRPA	forelimb digit shape	both	0.0 %	1.0
SHIRPA	forelimb digit size	females	0.0 %	1.0
SHIRPA	forelimb digit size	males	0.0 %	1.0
SHIRPA	forelimb digit size	both	0.0 %	1.0
SHIRPA	forelimb footpads	females	0.0 %	1.0
SHIRPA	forelimb footpads	males	0.0 %	1.0
SHIRPA	forelimb footpads	both	0.0 %	1.0
SHIRPA	forelimb nail length	females	0.0 %	1.0
SHIRPA	forelimb nail length	males	0.0 %	1.0
SHIRPA	forelimb nail length	both	0.0 %	1.0
SHIRPA	forelimb nail number	females	0.0 %	1.0
SHIRPA	forelimb nail number	males	0.0 %	1.0
SHIRPA	forelimb nail number	both	0.0 %	1.0
SHIRPA	forelimb nail position	females	0.0 %	1.0
SHIRPA	forelimb nail position	males	0.0 %	1.0
SHIRPA	forelimb nail position	both	0.0 %	1.0
SHIRPA	forelimb nail shape	females	0.0 %	1.0
SHIRPA	forelimb nail shape	males	0.0 %	1.0
SHIRPA	forelimb nail shape	both	0.0 %	1.0
SHIRPA	forelimbs position	females	0.0 %	1.0
SHIRPA	forelimbs position	males	0.0 %	1.0
SHIRPA	forelimbs position	both	0.0 %	1.0
SHIRPA	forelimbs shape	females	0.0 %	1.0
SHIRPA	forelimbs shape	males	0.0 %	1.0
SHIRPA	forelimbs shape	both	0.0 %	1.0
SHIRPA	forelimbs size	females	0.0 %	1.0
SHIRPA	forelimbs size	males	0.0 %	1.00
SHIRPA	forelimbs size	both	0.0 %	1.0
SHIRPA	forepaw position	females	0.0 %	1.0
SHIRPA	forepaw position	males	0.0 %	1.0
SHIRPA	forepaw position	both	0.0 %	1.0
SHIRPA	forepaw shape	females	0.0 %	1.0
SHIRPA	forepaw shape	males	0.0 %	1.0
SHIRPA	forepaw shape	both	0.0 %	1.0
SHIRPA	forepaw size	females	0.0 %	1.0
SHIRPA	forepaw size	males	0.0 %	1.0
SHIRPA	forepaw size	both	0.0 %	1.0
SHIRPA	gait (fluidity)	females	0.0 %	1.0
SHIRPA	gait (fluidity)	males	0.0 %	1.0
SHIRPA	gait (fluidity)	both	0.0 %	1.0
SHIRPA	genitalia morphology	females	0.0 %	1.00
SHIRPA	genitalia morphology	males	0.0 %	1.0
SHIRPA	genitalia morphology	both	0.0 %	1.00
SHIRPA	genitalia presence	females	0.0 %	1.0
SHIRPA	genitalia presence	males	0.0 %	1.0
SHIRPA	genitalia presence	both	0.0 %	1.0
SHIRPA	genitalia size	females	0.0 %	1.0
SHIRPA	genitalia size	males	0.0 %	1.00
SHIRPA	genitalia size	both	0.0 %	1.00
SHIRPA	head bobbing	females	0.0 %	1.0
SHIRPA	head bobbing	males	0.0 %	1.0
SHIRPA	head bobbing	both	0.0 %	1.0
SHIRPA	head morphology	females	0.0 %	1.0
SHIRPA	head morphology	males	0.0 %	1.0
SHIRPA	head morphology	both	0.0 %	1.0
SHIRPA	head size	females	0.0 %	1.0
SHIRPA	head size	males	0.0 %	1.00
SHIRPA	head size	both	0.0 %	1.0
SHIRPA	hindlimb digit number	females	1.0 %	1.00
SHIRPA	hindlimb digit number	males	0.0 %	1.0
SHIRPA	hindlimb digit number	both	0.0 %	1.0
SHIRPA	hindlimb digit position	females	0.0 %	1.0
SHIRPA	hindlimb digit position	males	0.0 %	1.0
SHIRPA	hindlimb digit position	both	0.0 %	1.0
SHIRPA	hindlimb digit shape	females	0.0 %	1.0
SHIRPA	hindlimb digit shape	males	0.0 %	1.0
SHIRPA	hindlimb digit shape	both	0.0 %	1.00
SHIRPA	hindlimb digit size	females	0.0 %	1.00
SHIRPA	hindlimb digit size	males	0.0 %	1.00
SHIRPA	hindlimb digit size	both	0.0 %	1.00
SHIRPA	hindlimb nail length	females	0.0 %	1.0
SHIRPA	hindlimb nail length	males	0.0 %	1.00
SHIRPA	hindlimb nail length	both	0.0 %	1.0
SHIRPA	hindlimb nail number	females	0.0 %	1.0
SHIRPA	hindlimb nail number	males	1.0 %	1.00
SHIRPA	hindlimb nail number	both	0.0 %	1.0
SHIRPA	hindlimb nail position	females	0.0 %	1.0
SHIRPA	hindlimb nail position	males	0.0 %	1.0
SHIRPA	hindlimb nail position	both	0.0 %	1.0
SHIRPA	hindlimb nail shape	females	0.0 %	1.0
SHIRPA	hindlimb nail shape	males	0.0 %	1.0
SHIRPA	hindlimb nail shape	both	0.0 %	1.0
SHIRPA	hindlimbs footpads	females	0.0 %	1.0
SHIRPA	hindlimbs footpads	males	0.0 %	1.0
SHIRPA	hindlimbs footpads	both	0.0 %	1.0
SHIRPA	hindlimbs position	females	0.0 %	1.0
SHIRPA	hindlimbs position	males	0.0 %	1.0
SHIRPA	hindlimbs position	both	0.0 %	1.0
SHIRPA	hindlimbs shape	females	0.0 %	1.0
SHIRPA	hindlimbs shape	males	0.0 %	1.0
SHIRPA	hindlimbs shape	both	0.0 %	1.0
SHIRPA	hindlimbs size	females	0.0 %	1.0
SHIRPA	hindlimbs size	males	0.0 %	1.0
SHIRPA	hindlimbs size	both	0.0 %	1.0
SHIRPA	hindpaw position	females	0.0 %	1.0
SHIRPA	hindpaw position	males	0.0 %	1.0
SHIRPA	hindpaw position	both	0.0 %	1.0
SHIRPA	hindpaw shape	females	0.0 %	1.0
SHIRPA	hindpaw shape	males	0.0 %	1.0
SHIRPA	hindpaw shape	both	0.0 %	1.0
SHIRPA	hindpaw size	females	0.0 %	1.0
SHIRPA	hindpaw size	males	0.0 %	1.0
SHIRPA	hindpaw size	both	0.0 %	1.0
SHIRPA	limb grasp	females	4.0 %	0.524
SHIRPA	limb grasp	males	6.0 %	1.0
SHIRPA	limb grasp	both	1.0 %	1.0
SHIRPA	lower lip morphology	females	0.0 %	1.0
SHIRPA	lower lip morphology	males	0.0 %	1.0
SHIRPA	lower lip morphology	both	0.0 %	1.0
SHIRPA	lower teeth appearance	females	0.0 %	1.0
SHIRPA	lower teeth appearance	males	0.0 %	1.0
SHIRPA	lower teeth appearance	both	0.0 %	1.0
SHIRPA	mouth morphology	females	0.0 %	1.0
SHIRPA	mouth morphology	males	0.0 %	1.0
SHIRPA	mouth morphology	both	0.0 %	1.0
SHIRPA	salivation	females	0.0 %	1.0
SHIRPA	salivation	males	0.0 %	1.0
SHIRPA	salivation	both	0.0 %	1.0
SHIRPA	skin color back paws	females	0.0 %	1.0
SHIRPA	skin color back paws	males	0.0 %	1.0
SHIRPA	skin color back paws	both	0.0 %	1.0
SHIRPA	skin color ear	females	0.0 %	1.0
SHIRPA	skin color ear	males	0.0 %	1.0
SHIRPA	skin color ear	both	0.0 %	1.0
SHIRPA	skin color front paws	females	0.0 %	1.0
SHIRPA	skin color front paws	males	0.0 %	1.0
SHIRPA	skin color front paws	both	0.0 %	1.0
SHIRPA	skin color snout	females	0.0 %	1.0
SHIRPA	skin color snout	males	0.0 %	1.0
SHIRPA	skin color snout	both	0.0 %	1.0
SHIRPA	skin color tail	females	0.0 %	1.0
SHIRPA	skin color tail	males	0.0 %	1.0
SHIRPA	skin color tail	both	0.0 %	1.0
SHIRPA	skin color whole body	females	0.0 %	1.0
SHIRPA	skin color whole body	males	0.0 %	1.0
SHIRPA	skin color whole body	both	0.0 %	1.0
SHIRPA	skin texture back paw	females	0.0 %	1.0
SHIRPA	skin texture back paw	males	0.0 %	1.0
SHIRPA	skin texture back paw	both	0.0 %	1.0
SHIRPA	skin texture ear	females	0.0 %	1.0
SHIRPA	skin texture ear	males	0.0 %	1.0
SHIRPA	skin texture ear	both	0.0 %	1.0
SHIRPA	skin texture front paws	females	0.0 %	1.0
SHIRPA	skin texture front paws	males	0.0 %	1.0
SHIRPA	skin texture front paws	both	0.0 %	1.0
SHIRPA	skin texture snout	females	0.0 %	1.0
SHIRPA	skin texture snout	males	0.0 %	1.0
SHIRPA	skin texture snout	both	0.0 %	1.0
SHIRPA	skin texture tail	females	0.0 %	1.0
SHIRPA	skin texture tail	males	0.0 %	1.0
SHIRPA	skin texture tail	both	0.0 %	1.0
SHIRPA	skin texture whole body	females	0.0 %	1.0
SHIRPA	skin texture whole body	males	0.0 %	1.0
SHIRPA	skin texture whole body	both	0.0 %	1.00
SHIRPA	snout size	females	0.0 %	1.0
SHIRPA	snout size	males	1.0 %	1.0
SHIRPA	snout size	both	0.0 %	1.0
SHIRPA	startle response	females	0.0 %	1.00
SHIRPA	startle response	males	14.0 %	0.0206
SHIRPA	startle response	both	6.0 %	0.0327
SHIRPA	tail curvature	females	0.0 %	1.00
SHIRPA	tail curvature	males	0.0 %	1.0
SHIRPA	tail curvature	both	0.0 %	1.00
SHIRPA	tail elevation	females	1.0 %	1.00
SHIRPA	tail elevation	males	13.0 %	0.125
SHIRPA	tail elevation	both	5.0 %	0.191
SHIRPA	tail length	females	0.0 %	1.0
SHIRPA	tail length	males	0.0 %	1.00
SHIRPA	tail length	both	0.0 %	1.0
SHIRPA	tail morphology	females	0.0 %	1.00
SHIRPA	tail morphology	males	0.0 %	1.00
SHIRPA	tail morphology	both	0.0 %	1.00
SHIRPA	tail presence	females	0.0 %	1.0
SHIRPA	tail presence	males	0.0 %	1.0
SHIRPA	tail presence	both	0.0 %	1.0
SHIRPA	tail shape	females	0.0 %	1.0
SHIRPA	tail shape	males	0.0 %	1.0
SHIRPA	tail shape	both	0.0 %	1.0
SHIRPA	tail thickness	females	0.0 %	1.0
SHIRPA	tail thickness	males	0.0 %	1.0
SHIRPA	tail thickness	both	0.0 %	1.0
SHIRPA	teeth presence	females	0.0 %	1.0
SHIRPA	teeth presence	males	0.0 %	1.0
SHIRPA	teeth presence	both	0.0 %	1.0
SHIRPA	transfer arousal	females	1.0 %	1.0
SHIRPA	transfer arousal	males	2.0 %	1.0
SHIRPA	transfer arousal	both	1.0 %	1.0
SHIRPA	tremor	females	0.0 %	1.0
SHIRPA	tremor	males	0.0 %	1.0
SHIRPA	tremor	both	0.0 %	1.00
SHIRPA	trunk curl	females	0.0 %	1.00
SHIRPA	trunk curl	males	0.0 %	1.0
SHIRPA	trunk curl	both	0.0 %	1.00
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	females	0.0 %	1.0
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	males	0.0 %	1.0
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	both	0.0 %	1.0
SHIRPA	upper lip morphology	females	0.0 %	1.0
SHIRPA	upper lip morphology	males	0.0 %	1.0
SHIRPA	upper lip morphology	both	0.0 %	1.0
SHIRPA	upper teeth appearance	females	0.0 %	1.0
SHIRPA	upper teeth appearance	males	0.0 %	1.00
SHIRPA	upper teeth appearance	both	0.0 %	1.0
SHIRPA	vibrissae appearance	females	2.0 %	1.0
SHIRPA	vibrissae appearance	males	1.0 %	1.0
SHIRPA	vibrissae appearance	both	1.0 %	1.0
SHIRPA	vibrissae presence	females	2.0 %	1.00
SHIRPA	vibrissae presence	males	1.0 %	1.0
SHIRPA	vibrissae presence	both	2.0 %	1.0
SHIRPA	vocalization	females	2.0 %	1.00
SHIRPA	vocalization	males	2.0 %	1.0
SHIRPA	vocalization	both	2.0 %	1.0

GENOTYPE CORRELATION PLOT

Correlate Psd4^{tm1.1(KOMP)Vlcg}/2J -/- with genotype: