MPD: JaxKOMP-EAP genotype: Mon1a<sup>em1(IMPC)J</sup> -/-

JaxKOMP-EAP effect sizes: Mon1a^em1(IMPC)J -/- Gene Mon1a

MULTIPLE (NUMERIC) TRAIT PROFILE PLOT — Early Adult Phenotyping study (EAP)

Procedure	JaxKOMP-EAP Trait	Trait Effect	Trait Effect SE	Trait Effect RankZ	Adjusted p-value	Unadjusted p-value
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 6 kHz pip	-2.6859	1.3577	-1.0049	0.425	0.0713
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 12 kHz pip	1.1246	2.5642	0.25569	0.904	0.668
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 18 kHz pip	-1.5671	3.4104	-0.53666	0.878	0.654
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 24 kHz pip	-6.8746	3.8020	-1.1603	0.420	0.0938
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 30 kHz pip	5.0142	4.2568	0.77287	0.642	0.262
body composition	body length	-0.044447	0.050877	-0.31774	0.678	0.387
body composition	body weight (at time of DXA)	-0.16954	0.65794	-0.040264	0.900	0.798
body composition	bone area, whole body scan, head excluded	0.027757	0.14534	0.29503	0.936	0.849
body composition	bone mineral content of whole body scan, head excluded	0.0094325	0.011065	0.69000	0.670	0.398
body composition	bone mineral content to body weight ratio	0.00019385	0.00044637	0.42325	0.832	0.666
body composition	bone mineral density of whole body scan, head excluded	0.00092123	0.00049565	1.0441	0.283	0.0696
body composition	fat tissue mass of whole body scan, head excluded	0.020795	0.32938	0.028675	0.975	0.950
body composition	fat tissue mass to body weight ratio	-0.0026977	0.011820	-0.064212	0.917	0.820
body composition	lean tissue mass of whole body scan, head excluded	0.42182	0.27100	0.71975	0.412	0.127
body composition	lean tissue mass to body weight ratio	0.0077201	0.0093294	0.36517	0.653	0.412
body composition	percent fat, whole body scan, head excluded	-0.41946	1.1247	-0.13420	0.866	0.711
body composition	ratio of soft-tissue attenuation coefficients	0.00045695	0.0012476	0.14002	0.871	0.716
body composition	tissue area	0.0021535	0.13780	0.21346	0.998	0.988
body composition	total tissue mass, whole body scan, head excluded	0.46884	0.21069	0.77021	0.151	0.0311
clinical blood chemistry	alanine transaminase (plasma ALT)	-9.6496	7.5598	-0.81526	0.593	0.215
clinical blood chemistry	albumin (plasma Alb)	0.023279	0.48710	0.10428	0.989	0.962
clinical blood chemistry	alkaline phosphatase (plasma ALP)	7.3057	2.8815	0.74607	0.108	0.0192
clinical blood chemistry	aspartate transaminase (plasma AST)	-29.607	25.189	-1.2809	0.567	0.252
clinical blood chemistry	aspartate transaminase to alanine transaminase ratio (plasma AST:ALT)	-0.093111	0.38124	-0.29966	0.939	0.809
clinical blood chemistry	blood urea nitrogen (BUN)	-1.0271	1.3335	-0.47199	0.700	0.449
clinical blood chemistry	calcium (plasma Ca)	-0.27022	0.095235	-1.5537	0.0704	0.00958
clinical blood chemistry	creatinine (plasma)	-0.091573	0.030162	-1.6092	0.0714	0.00955
clinical blood chemistry	glucose (plasma GLU, no fast)	-9.6154	12.498	-0.082219	0.651	0.450
clinical blood chemistry	HDL cholesterol (plasma HDL)	-0.046312	2.8759	-0.34014	0.998	0.987
clinical blood chemistry	HDL cholesterol to total cholesterol ratio	0.014806	0.0078481	0.68210	0.346	0.0725
clinical blood chemistry	phosphorus (plasma phosphate)	-0.43003	0.36763	-0.74367	0.543	0.255
clinical blood chemistry	total bilirubin (plasma TBIL)	-0.016923	0.0089519	-1.1691	0.312	0.0719
clinical blood chemistry	total cholesterol (plasma CHOL, no fast)	-2.2854	3.9364	-0.62488	0.821	0.568
clinical blood chemistry	total protein (plasma TP)	1.0750	0.79879	0.79220	0.476	0.193
clinical blood chemistry	triglyceride (plasma TG, no fast)	-13.382	7.9327	-0.50415	0.356	0.106
EKG	duration of PQ interval	0.84391	0.69078	1.0524	0.786	0.230
EKG	duration of PR interval	0.63863	0.74063	0.75515	0.877	0.395
EKG	duration of QRS interval	-0.030882	0.23906	-0.22349	0.990	0.898
EKG	duration of QT interval	1.1015	0.66846	1.1965	0.638	0.108
EKG	duration of QTC interval, calculated by dividing QT interval by square root of preceding RR interval	1.2324	0.66905	1.3020	0.666	0.0740
EKG	duration of RR interval	-0.59165	1.0377	-0.026198	0.840	0.572
EKG	duration of ST interval	1.1736	0.64776	1.4188	0.569	0.0786
EKG	heart rate coefficient of variation (signal intensity)	-0.95634	0.87109	-0.69744	0.848	0.280
EKG	heart rate variability, mean of differences between sequential beats; beats per min	-6.9772	6.2765	-0.76052	0.853	0.274
EKG	heart rate, beats per min	4.0456	8.9153	-0.025210	0.870	0.653
EKG	mean R amplitude, mean amplitude of signal measured from isoelectric line to peak of QRS	0.036101	0.088457	0.19174	0.898	0.686
EKG	mean SR amplitude, mean amplitude of signal measured from signal minimum line to peak of QRS	0.10297	0.11698	0.50804	0.705	0.385
EKG	number of signals	1.7831	3.1786	0.32182	0.883	0.578
EKG	proportion of number pairs of successive beat-to-beat intervals that exceed 50 ms	-2.0878	2.8394	-0.33151	0.859	0.467
EKG	QT dispersion, measured as inter-lead variability of QT intervals	-1.7537	3.1166	-0.49731	0.964	0.577
EKG	QTc dispersion, calculated as rate-corrected QT dispersion	-0.73676	3.6191	-0.18235	0.975	0.840
EKG	root mean square of successive differences of neighboring RR intervals	-1.2405	1.8914	-0.57170	0.899	0.516
glucose tolerance test	amount glucose injected	-14.123	3.1041	-2.3108	0.0112	0.0000561
glucose tolerance test	plasma glucose, 0min	-31.591	9.4893	-2.4512	0.0187	0.00195
glucose tolerance test	plasma glucose, 15min	30.919	23.343	0.98809	0.512	0.193
glucose tolerance test	plasma glucose, 30min	17.108	23.917	0.63957	0.757	0.479
glucose tolerance test	plasma glucose, 60min	-1.9616	15.174	0.063188	0.956	0.898
glucose tolerance test	plasma glucose, 120min	18.920	5.3809	1.1248	0.0391	0.00115
grip strength	body weight (at time of grip strength test)	-2.1858	0.57696	-1.5532	0.00600	0.000591
grip strength	forelimb and hindlimb grip strength (mean of trials), average	6.5642	9.7661	0.71235	0.697	0.506
grip strength	forelimb and hindlimb grip strength (mean of trials), average normalized to bw	0.47083	0.42461	0.88419	0.483	0.275
grip strength	forelimb and hindlimb grip strength by trial, trial1	-6.7052	10.621	-0.21365	0.780	0.532
grip strength	forelimb and hindlimb grip strength by trial, trial2	12.783	13.416	1.0387	0.595	0.348
grip strength	forelimb and hindlimb grip strength by trial, trial3	13.615	14.006	1.1031	0.606	0.338
grip strength	forelimb grip strength (mean of trials), average	-0.25198	4.9465	0.23002	0.988	0.960
grip strength	forelimb grip strength (mean of trials), average normalized to bw	0.18818	0.27250	0.73881	0.747	0.495
grip strength	forelimb grip strength by trial, trial1	4.3030	5.0160	0.76190	0.716	0.397
grip strength	forelimb grip strength by trial, trial2	11.716	8.3225	1.4664	0.484	0.169
grip strength	forelimb grip strength by trial, trial3	-2.8387	7.5749	-0.055215	0.882	0.710
heart weight	heart weight, normalized to body weight	0.31591	0.18884	0.64384	0.265	0.0999
heart weight	heart weight, weight	6.6637	5.0997	0.50358	0.400	0.197
hematology	basophil differential (percent of total WBC)	0.050734	0.074236	0.77538	0.827	0.500
hematology	calculated hemoglobin (cHGB)	0.14306	0.22008	0.15709	0.761	0.521
hematology	eosinophil differential (percent of total WBC)	0.39611	0.30761	1.1803	0.602	0.208
hematology	hematocrit (HCT)	0.10869	0.65458	-0.26692	0.939	0.869
hematology	hemoglobin concentration distribution width (HDW)	0.022102	0.016917	0.60934	0.506	0.202
hematology	large unstained cells (percent of total WBC)	-0.21309	0.14244	-1.3150	0.487	0.146
hematology	lymphocyte differential (percent of total WBC)	-0.73650	0.98892	-0.35881	0.681	0.462
hematology	mean corpuscular hemoglobin (CHr)	-0.058584	0.057388	-0.45871	0.557	0.316
hematology	mean platelet volume (MPV)	0.018160	0.083162	-0.054220	0.921	0.829
hematology	mean RBC corpuscular hemoglobin (MCH)	-0.19640	0.22214	-0.70041	0.727	0.384
hematology	mean RBC corpuscular hemoglobin concentration (MCHC)	-0.087939	0.57935	-0.19714	0.961	0.880
hematology	mean RBC corpuscular volume (MCV)	-0.47794	0.32317	-0.86086	0.341	0.150
hematology	measured hemoglobin (mHGB)	-0.044985	0.29726	-0.34810	0.949	0.881
hematology	monocyte differential (percent of total WBC)	-0.063269	0.17439	0.0054670	0.899	0.719
hematology	neutrophil differential (percent of total WBC)	0.52932	0.76443	0.28680	0.702	0.494
hematology	platelet count (PLT; units per volume x 10³)	-26.551	60.807	-0.31541	0.873	0.666
hematology	RBC corpuscular distribution width (RDW)	0.054369	0.11575	0.19655	0.815	0.642
hematology	RBC corpuscular hemoglobin concentration mean (CHCM)	0.26479	0.25116	0.63992	0.570	0.300
hematology	red blood cell count (RBC; per volume x 10⁶)	0.12351	0.15603	0.20810	0.683	0.435
hematology	reticulocyte count (Retic; units per volume x 10⁹)	-8.9071	14.806	-0.31341	0.836	0.552
hematology	reticulocyte differential (percent of total RBC)	-0.12521	0.14530	-0.33146	0.727	0.396
hematology	white blood cell count (WBC; units per volume x 10³)	-0.54304	0.71123	-0.20647	0.644	0.452
holeboard	number of hole pokes by individual hole number, 20 min test, 1	2.2523	0.84519	1.8666	0.330	0.0126
holeboard	number of hole pokes by individual hole number, 20 min test, 2	0.21537	0.43431	0.46808	0.904	0.624
holeboard	number of hole pokes by individual hole number, 20 min test, 3	0.32189	0.58808	0.63114	0.908	0.588
holeboard	number of hole pokes by individual hole number, 20 min test, 4	0.55613	0.71541	0.62088	0.820	0.443
holeboard	number of hole pokes by individual hole number, 20 min test, 5	0.53996	0.47379	0.92646	0.767	0.264
holeboard	number of hole pokes by individual hole number, 20 min test, 6	-0.18380	0.40003	-0.48569	0.940	0.649
holeboard	number of hole pokes by individual hole number, 20 min test, 7	0.24728	0.25123	0.65081	0.852	0.333
holeboard	number of hole pokes by individual hole number, 20 min test, 8	-0.87139	0.41432	-1.3311	0.501	0.0442
holeboard	number of hole pokes by individual hole number, 20 min test, 9	-0.48514	0.39988	-0.77101	0.702	0.235
holeboard	number of hole pokes by individual hole number, 20 min test, 10	-0.075000	0.28607	-0.13914	0.959	0.795
holeboard	number of hole pokes by individual hole number, 20 min test, 11	-0.62406	0.34472	-1.6462	0.673	0.0810
holeboard	number of hole pokes by individual hole number, 20 min test, 12	-0.062493	0.54432	0.0084342	0.976	0.909
holeboard	number of hole pokes by individual hole number, 20 min test, 13	1.3411	0.70955	1.2762	0.438	0.0688
holeboard	number of hole pokes by individual hole number, 20 min test, 14	0.041876	0.40401	0.14217	0.984	0.918
holeboard	number of hole pokes by individual hole number, 20 min test, 15	-0.72500	0.52960	-1.0654	0.652	0.182
holeboard	number of hole pokes by individual hole number, 20 min test, 16	2.5934	0.78803	2.1576	0.150	0.00263
holeboard	total number of hole pokes, 20 min test	2.8443	3.2719	0.46868	0.663	0.392
light / dark	fecal boli count, 20 min test	-0.96342	0.81339	-1.0768	0.646	0.241
light / dark	latency to enter dark zone, 20 min test	4.1798	33.623	-0.036512	0.974	0.901
light / dark	number of transitions between light and dark zones, 20 min test	-12.255	7.1785	-1.1367	0.368	0.0930
light / dark	percentage of total time in dark zone, 20 min test	2.7780	3.1771	0.61213	0.706	0.385
light / dark	percentage of total time in light zone, 20 min test	-2.7780	3.1771	-0.61539	0.704	0.385
light / dark	time mobile in dark zone, 20 min test	0.38148	10.799	-0.069007	0.992	0.972
light / dark	time mobile in light zone, 20 min test	-5.3883	10.689	-0.64341	0.813	0.616
light / dark	time spent in dark zone, 20 min test	-6.3628	40.474	0.12471	0.962	0.876
light / dark	time spent in light zone, 20 min test	6.3628	40.474	-0.12471	0.962	0.876
open field	average speed in center of arena, 20 min test	0.35955	0.45252	0.56033	0.747	0.431
open field	average speed in periphery of arena, 20 min test	-0.075587	0.17827	-0.79177	0.820	0.673
open field	distance traveled habituation ratio, 20 min test	-1.1670	7.7584	-0.044992	0.951	0.881
open field	distance traveled in center of arena, 20 min test	24.775	103.46	-0.25030	0.900	0.812
open field	distance traveled in periphery of arena, 20 min test	67.055	184.23	-0.17066	0.852	0.717
open field	distance traveled slope, 20 min test	-2.9560	7.3588	-0.20209	0.883	0.690
open field	distance traveled, 20 min test, 1st 5min	-21.036	76.637	-0.51994	0.906	0.785
open field	distance traveled, 20 min test, 2nd 5min	28.954	64.792	-0.16658	0.831	0.657
open field	distance traveled, 20 min test, 3rd 5min	-18.616	62.883	-0.65398	0.900	0.768
open field	distance traveled, 20 min test, 4th 5min	4.9252	62.774	-0.40193	0.975	0.938
open field	number of clockwise revolution episodes, 20 min test	1.3235	1.2403	0.37104	0.646	0.291
open field	number of counter-clockwise revolution episodes, 20 min test	-1.7965	1.4796	-1.4064	0.516	0.231
open field	number of fecal boli, 20 min test	-1.8324	1.1095	-1.1674	0.391	0.105
open field	number of rears in 5 min bins, 20 min test, 1st 5min	1.3041	2.0311	0.14966	0.751	0.524
open field	number of rears in 5 min bins, 20 min test, 2nd 5min	3.0396	2.2404	0.43860	0.466	0.181
open field	number of rears in 5 min bins, 20 min test, 3rd 5min	3.4635	2.6578	0.50921	0.473	0.199
open field	number of rears in 5 min bins, 20 min test, 4th 5min	6.1570	3.1622	1.0161	0.256	0.0574
open field	percentage of total time in center of arena, 20 min test	-1.7789	3.0342	-0.64074	0.818	0.560
open field	percentage of total time in center of arena, slope, 20 min test	0.44397	1.4545	0.36436	0.946	0.762
open field	percentage of total time in center, habituation ratio, 20 min test	0.14457	1.4725	0.19661	0.978	0.922
open field	percentage of total time in corners of arena, 20 min test	2.9580	3.2637	0.85200	0.668	0.369
open field	percentage of total time in corners, habituation ratio, 20 min test	-1.8786	1.5791	-1.1513	0.745	0.240
open field	percentage of total time in corners, slope, 20 min test	-1.8849	1.5280	-1.1566	0.707	0.223
open field	permanence time in center of arena, 20 min test	-21.372	36.411	-0.64074	0.818	0.560
open field	permanence time in corners of arena, 20 min test	35.501	39.164	0.85200	0.667	0.369
open field	permanence time in periphery of arena, 20 min test	21.433	36.409	0.64239	0.817	0.559
open field	total distance traveled, 20 min test	-96.623	227.80	-0.78080	0.825	0.673
open field	total number of rears, 20 min test	14.893	8.7062	0.65898	0.289	0.0936
open field	whole arena average speed, 20 min test	-0.078932	0.18996	-0.77353	0.829	0.680
open field	whole arena resting time, 20 min test	7.8925	20.585	0.78810	0.829	0.703
open field	whole arena time spent mobile, 20 min test	-7.7957	20.563	-0.91141	0.839	0.706
open field	whole arena time spent vertical, 20 min test	25.928	10.958	1.7069	0.172	0.0221
SHIRPA	locomotor activity (number of squares in the arena the mouse moves into with all four paws in first 30 s of test)	-0.74000	1.3994	-0.13525	0.824	0.603
startle / PPI	average baseline movement during background noise	-0.83083	1.1459	-0.57443	0.877	0.471
startle / PPI	average of each corrected maximum percent pre-pulse inhibition value	0.21623	0.73588	1.7288	0.904	0.770
startle / PPI	average of each corrected percent pre-pulse inhibition value	0.097389	0.061509	0.86667	0.439	0.119
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-1.8992	6.7973	-0.14978	0.970	0.781
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	10.393	6.6173	1.0066	0.473	0.122
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	13.175	5.3093	1.2409	0.140	0.0159
startle / PPI	average startle response to full pulse (120 dB)	-35.854	27.348	-0.49045	0.426	0.195
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-31.239	25.428	-0.44357	0.457	0.224
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-50.810	26.614	-0.79616	0.203	0.0611
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-25.993	22.264	-0.44512	0.466	0.248
startle / PPI	average startle response to pre-pulse, 74dB sound pressure level	0.059813	1.1060	0.12432	0.992	0.957
startle / PPI	average startle response to pre-pulse, 78dB sound pressure level	-0.10627	1.2282	-0.044150	0.991	0.931
startle / PPI	average startle response to pre-pulse, 82dB sound pressure level	-1.6417	1.3754	-1.0665	0.678	0.237
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	0.010367	0.079496	0.14128	0.990	0.897
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	0.10926	0.075739	0.84442	0.493	0.154
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	0.16304	0.072456	1.0417	0.151	0.0282
startle / PPI	corrected average startle response to full pulse (120 dB) minus average baseline movement during background noise	-34.945	27.585	-0.47158	0.439	0.210
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 74dB sound pressure level	-31.361	25.377	-0.44203	0.452	0.221
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 78dB sound pressure level	-49.486	26.450	-0.77329	0.212	0.0663
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 82dB sound pressure level	-24.753	22.361	-0.39159	0.490	0.273
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	0.0091048	0.080027	0.12150	0.990	0.910
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	0.14007	0.080055	1.0039	0.382	0.0854
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	0.47219	2.1640	2.2303	0.938	0.828
startle / PPI	corrected maximum startle response to full pulse (120 dB) minus maximum baseline movement during background noise	-133.88	101.70	-0.48888	0.415	0.193
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 74dB sound pressure level	-105.59	91.453	-0.41439	0.488	0.253
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 78dB sound pressure level	-184.20	98.324	-0.77707	0.210	0.0660
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 82dB sound pressure level	-144.64	79.292	-0.71236	0.223	0.0732
startle / PPI	maximum baseline movement during background noise	-2.8938	2.5045	-0.80002	0.737	0.253
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-1.6635	7.0562	-0.12997	0.977	0.814
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	12.681	7.3682	1.1044	0.412	0.0905
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	14.002	6.0191	1.1412	0.158	0.0235
startle / PPI	maximum startle response to full pulse (120 dB)	-137.04	101.11	-0.50314	0.402	0.180
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-106.84	91.661	-0.41897	0.488	0.248
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-187.67	98.628	-0.79041	0.202	0.0620
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-149.54	79.286	-0.75267	0.207	0.0642
startle / PPI	maximum startle response to pre-pulse, 74dB sound pressure level	-1.5110	2.6760	-0.38555	0.890	0.574
startle / PPI	maximum startle response to pre-pulse, 78dB sound pressure level	-0.69593	2.4875	-0.18816	0.964	0.781
startle / PPI	maximum startle response to pre-pulse, 82dB sound pressure level	-5.1004	3.3442	-1.2655	0.511	0.133

MULTIPLE (CATEGORICAL) TRAIT PROFILE PLOT — Early Adult Phenotyping study (EAP)

Procedure	JaxKOMP-EAP Trait	Sex	Trait Effect	P-value
eye morphology	anterior chamber depth	females	12.0 %	0.0556
eye morphology	anterior chamber depth	males	0.0 %	1.0
eye morphology	anterior chamber depth	both	7.0 %	0.0495
eye morphology	bulging eye	females	12.0 %	0.0359
eye morphology	bulging eye	males	0.0 %	1.0
eye morphology	bulging eye	both	8.0 %	0.0330
eye morphology	cornea	females	12.0 %	0.0773
eye morphology	cornea	males	2.0 %	1.0
eye morphology	cornea	both	8.0 %	0.0839
eye morphology	cornea opacity	females	20.0 %	0.0275
eye morphology	cornea opacity	males	1.0 %	1.0
eye morphology	cornea opacity	both	12.0 %	0.0248
eye morphology	cornea vascularization	females	12.0 %	0.0534
eye morphology	cornea vascularization	males	1.0 %	1.0
eye morphology	cornea vascularization	both	8.0 %	0.0543
eye morphology	corneal deposits	females	12.0 %	0.0944
eye morphology	corneal deposits	males	1.0 %	1.0
eye morphology	corneal deposits	both	7.0 %	0.0856
eye morphology	corneal mineralization	females	12.0 %	0.103
eye morphology	corneal mineralization	males	1.0 %	1.0
eye morphology	corneal mineralization	both	8.0 %	0.0482
eye morphology	corneal scleralization	females	22.0 %	0.0116
eye morphology	corneal scleralization	males	1.0 %	1.0
eye morphology	corneal scleralization	both	13.0 %	0.0182
eye morphology	corneal ulcer	females	12.0 %	0.0595
eye morphology	corneal ulcer	males	1.0 %	1.0
eye morphology	corneal ulcer	both	8.0 %	0.0599
eye morphology	eye closure	females	12.0 %	0.0358
eye morphology	eye closure	males	0.0 %	1.0
eye morphology	eye closure	both	8.0 %	0.0328
eye morphology	eye hemorrhage or blood presence	females	12.0 %	0.0696
eye morphology	eye hemorrhage or blood presence	males	1.0 %	1.0
eye morphology	eye hemorrhage or blood presence	both	8.0 %	0.0720
eye morphology	eyelid morphology	females	12.0 %	0.0443
eye morphology	eyelid morphology	males	0.0 %	1.0
eye morphology	eyelid morphology	both	8.0 %	0.0398
eye morphology	eyes (present, absent)	females	12.0 %	0.0433
eye morphology	eyes (present, absent)	males	0.0 %	1.0
eye morphology	eyes (present, absent)	both	8.0 %	0.0403
eye morphology	fusion between cornea and lens	females	11.0 %	0.144
eye morphology	fusion between cornea and lens	males	2.0 %	1.0
eye morphology	fusion between cornea and lens	both	7.0 %	0.144
eye morphology	iris pigmentation	females	12.0 %	0.166
eye morphology	iris pigmentation	males	1.0 %	1.0
eye morphology	iris pigmentation	both	7.0 %	0.117
eye morphology	iris transillumination	females	12.0 %	0.146
eye morphology	iris transillumination	males	1.0 %	1.00
eye morphology	iris transillumination	both	7.0 %	0.0946
eye morphology	irispupil	females	12.0 %	0.193
eye morphology	irispupil	males	3.0 %	1.0
eye morphology	irispupil	both	7.0 %	0.132
eye morphology	lacrimation	females	11.0 %	0.244
eye morphology	lacrimation	males	2.0 %	1.0
eye morphology	lacrimation	both	8.0 %	0.191
eye morphology	lens	females	11.0 %	0.276
eye morphology	lens	males	8.0 %	1.00
eye morphology	lens	both	7.0 %	0.283
eye morphology	lens opacity	females	53.0 %	0.0000162
eye morphology	lens opacity	males	40.0 %	0.00101
eye morphology	lens opacity	both	47.0 %	1.49e-7
eye morphology	narrow eye opening	females	23.0 %	0.00720
eye morphology	narrow eye opening	males	1.0 %	1.0
eye morphology	narrow eye opening	both	14.0 %	0.00485
eye morphology	optic disc	females	11.0 %	0.180
eye morphology	optic disc	males	2.0 %	1.0
eye morphology	optic disc	both	7.0 %	0.197
eye morphology	persistence of hyaloid vascular system	females	12.0 %	0.0547
eye morphology	persistence of hyaloid vascular system	males	5.0 %	1.0
eye morphology	persistence of hyaloid vascular system	both	8.0 %	0.0654
eye morphology	pupil dilation	females	12.0 %	0.171
eye morphology	pupil dilation	males	1.0 %	1.0
eye morphology	pupil dilation	both	7.0 %	0.134
eye morphology	pupil light response	females	11.0 %	0.179
eye morphology	pupil light response	males	1.0 %	1.0
eye morphology	pupil light response	both	7.0 %	0.197
eye morphology	pupil position	females	12.0 %	0.213
eye morphology	pupil position	males	3.0 %	1.0
eye morphology	pupil position	both	7.0 %	0.144
eye morphology	pupil shape	females	12.0 %	0.176
eye morphology	pupil shape	males	2.0 %	1.0
eye morphology	pupil shape	both	7.0 %	0.150
eye morphology	retina	females	40.0 %	0.00272
eye morphology	retina	males	14.0 %	0.580
eye morphology	retina	both	26.0 %	0.00989
eye morphology	retinal blood vessels	females	11.0 %	0.154
eye morphology	retinal blood vessels	males	2.0 %	1.0
eye morphology	retinal blood vessels	both	7.0 %	0.159
eye morphology	retinal blood vessels pattern	females	11.0 %	0.216
eye morphology	retinal blood vessels pattern	males	2.0 %	1.00
eye morphology	retinal blood vessels pattern	both	7.0 %	0.230
eye morphology	retinal blood vessels structure	females	11.0 %	0.165
eye morphology	retinal blood vessels structure	males	2.0 %	1.0
eye morphology	retinal blood vessels structure	both	7.0 %	0.175
eye morphology	retinal pigmentation	females	11.0 %	0.317
eye morphology	retinal pigmentation	males	17.0 %	0.363
eye morphology	retinal pigmentation	both	7.0 %	0.187
eye morphology	retinal structure	females	11.0 %	0.167
eye morphology	retinal structure	males	2.0 %	1.00
eye morphology	retinal structure	both	7.0 %	0.181
eye morphology	synechia	females	11.0 %	0.161
eye morphology	synechia	males	2.0 %	1.0
eye morphology	synechia	both	7.0 %	0.162
eye morphology	vitreous	females	11.0 %	0.152
eye morphology	vitreous	males	2.0 %	1.0
eye morphology	vitreous	both	7.0 %	0.153
SHIRPA	activity body position	females	1.0 %	1.0
SHIRPA	activity body position	males	2.0 %	1.0
SHIRPA	activity body position	both	1.0 %	1.00
SHIRPA	aggression	females	0.0 %	1.00
SHIRPA	aggression	males	1.0 %	1.0
SHIRPA	aggression	both	1.0 %	1.0
SHIRPA	body length	females	0.0 %	1.00
SHIRPA	body length	males	0.0 %	1.0
SHIRPA	body length	both	0.0 %	1.00
SHIRPA	body position	females	0.0 %	1.00
SHIRPA	body position	males	1.0 %	1.0
SHIRPA	body position	both	0.0 %	1.0
SHIRPA	body thickness	females	1.0 %	1.0
SHIRPA	body thickness	males	0.0 %	1.0
SHIRPA	body thickness	both	0.0 %	1.0
SHIRPA	coat color abdomen	females	3.0 %	1.00
SHIRPA	coat color abdomen	males	4.0 %	1.0
SHIRPA	coat color abdomen	both	4.0 %	1.0
SHIRPA	coat color back	females	0.0 %	1.0
SHIRPA	coat color back	males	0.0 %	1.00
SHIRPA	coat color back	both	0.0 %	1.0
SHIRPA	coat color head	females	0.0 %	1.0
SHIRPA	coat color head	males	0.0 %	1.00
SHIRPA	coat color head	both	0.0 %	1.0
SHIRPA	coat color pattern abdomen	females	1.0 %	1.0
SHIRPA	coat color pattern abdomen	males	1.0 %	1.0
SHIRPA	coat color pattern abdomen	both	1.0 %	1.0
SHIRPA	coat color pattern back	females	0.0 %	1.00
SHIRPA	coat color pattern back	males	0.0 %	1.00
SHIRPA	coat color pattern back	both	0.0 %	1.0
SHIRPA	coat color pattern head	females	0.0 %	1.0
SHIRPA	coat color pattern head	males	0.0 %	1.0
SHIRPA	coat color pattern head	both	0.0 %	1.00
SHIRPA	coat hair abdomen texture appearance	females	2.0 %	1.0
SHIRPA	coat hair abdomen texture appearance	males	2.0 %	1.0
SHIRPA	coat hair abdomen texture appearance	both	2.0 %	1.0
SHIRPA	coat hair back texture appearance	females	0.0 %	1.0
SHIRPA	coat hair back texture appearance	males	0.0 %	1.0
SHIRPA	coat hair back texture appearance	both	0.0 %	1.0
SHIRPA	coat hair distribution abdomen	females	0.0 %	1.00
SHIRPA	coat hair distribution abdomen	males	1.0 %	1.0
SHIRPA	coat hair distribution abdomen	both	1.0 %	1.0
SHIRPA	coat hair distribution back	females	0.0 %	1.00
SHIRPA	coat hair distribution back	males	0.0 %	1.0
SHIRPA	coat hair distribution back	both	0.0 %	1.00
SHIRPA	coat hair distribution head	females	1.0 %	1.00
SHIRPA	coat hair distribution head	males	1.0 %	1.0
SHIRPA	coat hair distribution head	both	1.0 %	1.0
SHIRPA	coat hair head texture appearance	females	0.0 %	1.0
SHIRPA	coat hair head texture appearance	males	0.0 %	1.0
SHIRPA	coat hair head texture appearance	both	0.0 %	1.0
SHIRPA	contact righting	females	5.0 %	1.0
SHIRPA	contact righting	males	5.0 %	1.0
SHIRPA	contact righting	both	5.0 %	1.0
SHIRPA	ear morphology	females	0.0 %	1.0
SHIRPA	ear morphology	males	0.0 %	1.0
SHIRPA	ear morphology	both	0.0 %	1.0
SHIRPA	fat distribution	females	0.0 %	1.0
SHIRPA	fat distribution	males	0.0 %	1.0
SHIRPA	fat distribution	both	0.0 %	1.0
SHIRPA	forelimb digit number	females	0.0 %	1.0
SHIRPA	forelimb digit number	males	0.0 %	1.0
SHIRPA	forelimb digit number	both	0.0 %	1.0
SHIRPA	forelimb digit position	females	0.0 %	1.0
SHIRPA	forelimb digit position	males	0.0 %	1.0
SHIRPA	forelimb digit position	both	0.0 %	1.0
SHIRPA	forelimb digit shape	females	0.0 %	1.0
SHIRPA	forelimb digit shape	males	0.0 %	1.0
SHIRPA	forelimb digit shape	both	0.0 %	1.0
SHIRPA	forelimb digit size	females	0.0 %	1.0
SHIRPA	forelimb digit size	males	0.0 %	1.0
SHIRPA	forelimb digit size	both	0.0 %	1.0
SHIRPA	forelimb footpads	females	0.0 %	1.0
SHIRPA	forelimb footpads	males	0.0 %	1.0
SHIRPA	forelimb footpads	both	0.0 %	1.0
SHIRPA	forelimb nail length	females	0.0 %	1.0
SHIRPA	forelimb nail length	males	0.0 %	1.0
SHIRPA	forelimb nail length	both	0.0 %	1.0
SHIRPA	forelimb nail number	females	0.0 %	1.0
SHIRPA	forelimb nail number	males	0.0 %	1.0
SHIRPA	forelimb nail number	both	0.0 %	1.0
SHIRPA	forelimb nail position	females	0.0 %	1.0
SHIRPA	forelimb nail position	males	0.0 %	1.0
SHIRPA	forelimb nail position	both	0.0 %	1.0
SHIRPA	forelimb nail shape	females	0.0 %	1.0
SHIRPA	forelimb nail shape	males	0.0 %	1.0
SHIRPA	forelimb nail shape	both	0.0 %	1.0
SHIRPA	forelimbs position	females	0.0 %	1.0
SHIRPA	forelimbs position	males	0.0 %	1.0
SHIRPA	forelimbs position	both	0.0 %	1.0
SHIRPA	forelimbs shape	females	0.0 %	1.0
SHIRPA	forelimbs shape	males	0.0 %	1.0
SHIRPA	forelimbs shape	both	0.0 %	1.0
SHIRPA	forelimbs size	females	0.0 %	1.00
SHIRPA	forelimbs size	males	0.0 %	1.0
SHIRPA	forelimbs size	both	0.0 %	1.0
SHIRPA	forepaw position	females	0.0 %	1.0
SHIRPA	forepaw position	males	0.0 %	1.0
SHIRPA	forepaw position	both	0.0 %	1.0
SHIRPA	forepaw shape	females	0.0 %	1.0
SHIRPA	forepaw shape	males	0.0 %	1.0
SHIRPA	forepaw shape	both	0.0 %	1.0
SHIRPA	forepaw size	females	0.0 %	1.0
SHIRPA	forepaw size	males	0.0 %	1.0
SHIRPA	forepaw size	both	0.0 %	1.0
SHIRPA	gait (fluidity)	females	0.0 %	1.0
SHIRPA	gait (fluidity)	males	0.0 %	1.0
SHIRPA	gait (fluidity)	both	0.0 %	1.0
SHIRPA	genitalia morphology	females	0.0 %	1.0
SHIRPA	genitalia morphology	males	0.0 %	1.0
SHIRPA	genitalia morphology	both	0.0 %	1.0
SHIRPA	genitalia presence	females	0.0 %	1.0
SHIRPA	genitalia presence	males	0.0 %	1.0
SHIRPA	genitalia presence	both	0.0 %	1.0
SHIRPA	genitalia size	females	0.0 %	1.0
SHIRPA	genitalia size	males	0.0 %	1.0
SHIRPA	genitalia size	both	0.0 %	1.0
SHIRPA	head bobbing	females	0.0 %	1.0
SHIRPA	head bobbing	males	0.0 %	1.0
SHIRPA	head bobbing	both	0.0 %	1.0
SHIRPA	head morphology	females	0.0 %	1.0
SHIRPA	head morphology	males	0.0 %	1.0
SHIRPA	head morphology	both	0.0 %	1.0
SHIRPA	head size	females	0.0 %	1.0
SHIRPA	head size	males	0.0 %	1.0
SHIRPA	head size	both	0.0 %	1.0
SHIRPA	hindlimb digit number	females	1.0 %	1.0
SHIRPA	hindlimb digit number	males	0.0 %	1.0
SHIRPA	hindlimb digit number	both	0.0 %	1.0
SHIRPA	hindlimb digit position	females	0.0 %	1.0
SHIRPA	hindlimb digit position	males	0.0 %	1.0
SHIRPA	hindlimb digit position	both	0.0 %	1.0
SHIRPA	hindlimb digit shape	females	0.0 %	1.00
SHIRPA	hindlimb digit shape	males	0.0 %	1.0
SHIRPA	hindlimb digit shape	both	0.0 %	1.00
SHIRPA	hindlimb digit size	females	0.0 %	1.0
SHIRPA	hindlimb digit size	males	0.0 %	1.0
SHIRPA	hindlimb digit size	both	0.0 %	1.0
SHIRPA	hindlimb nail length	females	0.0 %	1.0
SHIRPA	hindlimb nail length	males	0.0 %	1.0
SHIRPA	hindlimb nail length	both	0.0 %	1.0
SHIRPA	hindlimb nail number	females	0.0 %	1.0
SHIRPA	hindlimb nail number	males	1.0 %	1.0
SHIRPA	hindlimb nail number	both	0.0 %	1.0
SHIRPA	hindlimb nail position	females	0.0 %	1.0
SHIRPA	hindlimb nail position	males	0.0 %	1.0
SHIRPA	hindlimb nail position	both	0.0 %	1.0
SHIRPA	hindlimb nail shape	females	0.0 %	1.0
SHIRPA	hindlimb nail shape	males	0.0 %	1.0
SHIRPA	hindlimb nail shape	both	0.0 %	1.0
SHIRPA	hindlimbs footpads	females	0.0 %	1.0
SHIRPA	hindlimbs footpads	males	0.0 %	1.0
SHIRPA	hindlimbs footpads	both	0.0 %	1.0
SHIRPA	hindlimbs position	females	0.0 %	1.0
SHIRPA	hindlimbs position	males	0.0 %	1.0
SHIRPA	hindlimbs position	both	0.0 %	1.0
SHIRPA	hindlimbs shape	females	0.0 %	1.0
SHIRPA	hindlimbs shape	males	0.0 %	1.0
SHIRPA	hindlimbs shape	both	0.0 %	1.0
SHIRPA	hindlimbs size	females	0.0 %	1.0
SHIRPA	hindlimbs size	males	0.0 %	1.0
SHIRPA	hindlimbs size	both	0.0 %	1.0
SHIRPA	hindpaw position	females	0.0 %	1.0
SHIRPA	hindpaw position	males	0.0 %	1.0
SHIRPA	hindpaw position	both	0.0 %	1.0
SHIRPA	hindpaw shape	females	0.0 %	1.0
SHIRPA	hindpaw shape	males	0.0 %	1.0
SHIRPA	hindpaw shape	both	0.0 %	1.0
SHIRPA	hindpaw size	females	0.0 %	1.0
SHIRPA	hindpaw size	males	0.0 %	1.0
SHIRPA	hindpaw size	both	0.0 %	1.0
SHIRPA	limb grasp	females	9.0 %	1.00
SHIRPA	limb grasp	males	6.0 %	1.0
SHIRPA	limb grasp	both	7.0 %	1.0
SHIRPA	lower lip morphology	females	0.0 %	1.0
SHIRPA	lower lip morphology	males	0.0 %	1.0
SHIRPA	lower lip morphology	both	0.0 %	1.0
SHIRPA	lower teeth appearance	females	0.0 %	1.0
SHIRPA	lower teeth appearance	males	0.0 %	1.00
SHIRPA	lower teeth appearance	both	0.0 %	1.00
SHIRPA	mouth morphology	females	0.0 %	1.0
SHIRPA	mouth morphology	males	0.0 %	1.0
SHIRPA	mouth morphology	both	0.0 %	1.0
SHIRPA	salivation	females	0.0 %	1.0
SHIRPA	salivation	males	0.0 %	1.0
SHIRPA	salivation	both	0.0 %	1.0
SHIRPA	skin color back paws	females	0.0 %	1.0
SHIRPA	skin color back paws	males	0.0 %	1.0
SHIRPA	skin color back paws	both	0.0 %	1.0
SHIRPA	skin color ear	females	0.0 %	1.0
SHIRPA	skin color ear	males	0.0 %	1.0
SHIRPA	skin color ear	both	0.0 %	1.0
SHIRPA	skin color front paws	females	0.0 %	1.0
SHIRPA	skin color front paws	males	0.0 %	1.0
SHIRPA	skin color front paws	both	0.0 %	1.0
SHIRPA	skin color snout	females	0.0 %	1.0
SHIRPA	skin color snout	males	0.0 %	1.0
SHIRPA	skin color snout	both	0.0 %	1.0
SHIRPA	skin color tail	females	0.0 %	1.0
SHIRPA	skin color tail	males	0.0 %	1.0
SHIRPA	skin color tail	both	0.0 %	1.0
SHIRPA	skin color whole body	females	0.0 %	1.0
SHIRPA	skin color whole body	males	0.0 %	1.0
SHIRPA	skin color whole body	both	0.0 %	1.0
SHIRPA	skin texture back paw	females	0.0 %	1.0
SHIRPA	skin texture back paw	males	0.0 %	1.0
SHIRPA	skin texture back paw	both	0.0 %	1.0
SHIRPA	skin texture ear	females	0.0 %	1.0
SHIRPA	skin texture ear	males	0.0 %	1.0
SHIRPA	skin texture ear	both	0.0 %	1.0
SHIRPA	skin texture front paws	females	0.0 %	1.0
SHIRPA	skin texture front paws	males	0.0 %	1.0
SHIRPA	skin texture front paws	both	0.0 %	1.0
SHIRPA	skin texture snout	females	0.0 %	1.0
SHIRPA	skin texture snout	males	0.0 %	1.0
SHIRPA	skin texture snout	both	0.0 %	1.0
SHIRPA	skin texture tail	females	0.0 %	1.0
SHIRPA	skin texture tail	males	0.0 %	1.0
SHIRPA	skin texture tail	both	0.0 %	1.0
SHIRPA	skin texture whole body	females	0.0 %	1.0
SHIRPA	skin texture whole body	males	0.0 %	1.0
SHIRPA	skin texture whole body	both	0.0 %	1.0
SHIRPA	snout size	females	0.0 %	1.00
SHIRPA	snout size	males	16.0 %	0.0329
SHIRPA	snout size	both	9.0 %	0.0399
SHIRPA	startle response	females	0.0 %	1.00
SHIRPA	startle response	males	0.0 %	1.00
SHIRPA	startle response	both	0.0 %	1.0
SHIRPA	tail curvature	females	0.0 %	1.0
SHIRPA	tail curvature	males	0.0 %	1.0
SHIRPA	tail curvature	both	0.0 %	1.00
SHIRPA	tail elevation	females	1.0 %	1.0
SHIRPA	tail elevation	males	2.0 %	1.0
SHIRPA	tail elevation	both	1.0 %	1.0
SHIRPA	tail length	females	0.0 %	1.0
SHIRPA	tail length	males	0.0 %	1.0
SHIRPA	tail length	both	0.0 %	1.00
SHIRPA	tail morphology	females	0.0 %	1.00
SHIRPA	tail morphology	males	0.0 %	1.0
SHIRPA	tail morphology	both	0.0 %	1.0
SHIRPA	tail presence	females	0.0 %	1.0
SHIRPA	tail presence	males	0.0 %	1.0
SHIRPA	tail presence	both	0.0 %	1.0
SHIRPA	tail shape	females	0.0 %	1.0
SHIRPA	tail shape	males	0.0 %	1.0
SHIRPA	tail shape	both	0.0 %	1.00
SHIRPA	tail thickness	females	0.0 %	1.0
SHIRPA	tail thickness	males	0.0 %	1.0
SHIRPA	tail thickness	both	0.0 %	1.0
SHIRPA	teeth presence	females	0.0 %	1.0
SHIRPA	teeth presence	males	0.0 %	1.0
SHIRPA	teeth presence	both	0.0 %	1.00
SHIRPA	transfer arousal	females	1.0 %	1.0
SHIRPA	transfer arousal	males	2.0 %	1.0
SHIRPA	transfer arousal	both	1.0 %	1.0
SHIRPA	tremor	females	0.0 %	1.00
SHIRPA	tremor	males	0.0 %	1.00
SHIRPA	tremor	both	0.0 %	1.0
SHIRPA	trunk curl	females	0.0 %	1.00
SHIRPA	trunk curl	males	0.0 %	1.0
SHIRPA	trunk curl	both	0.0 %	1.0
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	females	0.0 %	1.0
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	males	0.0 %	1.0
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	both	0.0 %	1.0
SHIRPA	upper lip morphology	females	0.0 %	1.0
SHIRPA	upper lip morphology	males	0.0 %	1.0
SHIRPA	upper lip morphology	both	0.0 %	1.0
SHIRPA	upper teeth appearance	females	0.0 %	1.0
SHIRPA	upper teeth appearance	males	0.0 %	1.0
SHIRPA	upper teeth appearance	both	0.0 %	1.00
SHIRPA	vibrissae appearance	females	2.0 %	1.0
SHIRPA	vibrissae appearance	males	1.0 %	1.0
SHIRPA	vibrissae appearance	both	1.0 %	1.0
SHIRPA	vibrissae presence	females	2.0 %	1.0
SHIRPA	vibrissae presence	males	1.0 %	1.0
SHIRPA	vibrissae presence	both	2.0 %	1.0
SHIRPA	vocalization	females	2.0 %	1.0
SHIRPA	vocalization	males	2.0 %	1.0
SHIRPA	vocalization	both	2.0 %	1.0

GENOTYPE CORRELATION PLOT

Correlate Mon1a^em1(IMPC)J -/- with genotype:

This genotype correlation visualization can include both EAP and LAP measures.