MPD: JaxKOMP-EAP genotype: Coq8b<sup>tm1b(EUCOMM)Hmgu</sup> -/+

JaxKOMP-EAP effect sizes: Coq8b^{tm1b(EUCOMM)Hmgu} -/+ Gene Coq8b

MULTIPLE (NUMERIC) TRAIT PROFILE PLOT — Early Adult Phenotyping study (EAP)

Procedure	JaxKOMP-EAP Trait	Trait Effect	Trait Effect SE	Trait Effect RankZ	Adjusted p-value	Unadjusted p-value
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 6 kHz pip	8.9159	2.4969	1.7615	0.110	0.00307
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 12 kHz pip	8.8133	2.5374	1.5321	0.124	0.00373
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 18 kHz pip	0.34746	7.8957	-0.10315	0.994	0.966
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 24 kHz pip	0.62500	3.3952	-0.027448	0.948	0.856
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 30 kHz pip	-5.8889	6.8571	-0.91077	0.733	0.405
body composition	body length	-0.077288	0.036894	-0.68704	0.209	0.0427
body composition	body weight (at time of DXA)	1.5794	0.56408	1.4086	0.0471	0.00783
body composition	bone area, whole body scan, head excluded	-0.58256	0.12413	-1.8067	0.00182	0.0000328
body composition	bone mineral content of whole body scan, head excluded	-0.033739	0.0086997	-1.4944	0.0123	0.000394
body composition	bone mineral content to body weight ratio	-0.0014202	0.00037852	-1.5070	0.0120	0.000570
body composition	bone mineral density of whole body scan, head excluded	-0.00059768	0.00040103	-0.65194	0.414	0.144
body composition	fat tissue mass of whole body scan, head excluded	0.80185	0.27542	1.1490	0.0617	0.00592
body composition	fat tissue mass to body weight ratio	0.030878	0.010420	1.2741	0.0484	0.00516
body composition	lean tissue mass of whole body scan, head excluded	-0.46250	0.25928	-1.0853	0.327	0.0822
body composition	lean tissue mass to body weight ratio	-0.018866	0.0095750	-1.0347	0.222	0.0559
body composition	percent fat, whole body scan, head excluded	2.8783	1.0130	1.3152	0.0596	0.00711
body composition	ratio of soft-tissue attenuation coefficients	-0.0031682	0.0011227	-1.2947	0.0611	0.00747
body composition	tissue area	-0.082440	0.17558	-0.10406	0.861	0.641
body composition	total tissue mass, whole body scan, head excluded	0.34297	0.15583	0.51471	0.157	0.0337
clinical blood chemistry	alanine transaminase (plasma ALT)	-12.193	22.408	-0.99455	0.857	0.590
clinical blood chemistry	albumin (plasma Alb)	0.74105	0.30121	1.0883	0.170	0.0199
clinical blood chemistry	alkaline phosphatase (plasma ALP)	-0.040185	1.8314	-0.53043	0.990	0.983
clinical blood chemistry	aspartate transaminase (plasma AST)	-36.781	24.013	-1.5318	0.443	0.136
clinical blood chemistry	aspartate transaminase to alanine transaminase ratio (plasma AST:ALT)	-0.49559	0.38659	-1.4177	0.611	0.210
clinical blood chemistry	blood urea nitrogen (BUN)	2.5017	1.2894	0.97546	0.234	0.0618
clinical blood chemistry	calcium (plasma Ca)	-0.076823	0.079853	-0.19821	0.586	0.344
clinical blood chemistry	creatinine (plasma)	-0.010281	0.021676	-0.15072	0.811	0.640
clinical blood chemistry	glucose (plasma GLU, no fast)	-7.6745	13.657	-0.0021424	0.750	0.578
clinical blood chemistry	HDL cholesterol (plasma HDL)	5.9253	2.3942	1.0157	0.153	0.0192
clinical blood chemistry	HDL cholesterol to total cholesterol ratio	-0.0019404	0.0099965	-0.26866	0.962	0.847
clinical blood chemistry	phosphorus (plasma phosphate)	0.12186	0.26897	0.15668	0.831	0.654
clinical blood chemistry	total bilirubin (plasma TBIL)	-0.017984	0.0081318	-1.2456	0.219	0.0350
clinical blood chemistry	total cholesterol (plasma CHOL, no fast)	8.0608	3.3391	1.0723	0.148	0.0221
clinical blood chemistry	total protein (plasma TP)	0.99495	0.53139	0.70528	0.301	0.0713
clinical blood chemistry	triglyceride (plasma TG, no fast)	9.5432	6.6556	0.72382	0.445	0.162
EKG	duration of PQ interval	-0.0038539	1.8295	0.15782	0.999	0.999
EKG	duration of PR interval	0.13145	1.6381	0.21936	0.987	0.943
EKG	duration of QRS interval	-0.64558	0.40505	-1.8966	0.885	0.252
EKG	duration of QT interval	2.0711	1.2598	1.8846	0.725	0.242
EKG	duration of QTC interval, calculated by dividing QT interval by square root of preceding RR interval	1.0350	1.1682	1.1028	0.912	0.469
EKG	duration of RR interval	4.5051	5.3005	2.2553	0.812	0.485
EKG	duration of ST interval	2.0354	1.8554	2.0860	0.809	0.387
EKG	heart rate coefficient of variation (signal intensity)	-0.12610	4.4589	0.0040300	0.990	0.980
EKG	heart rate variability, mean of differences between sequential beats; beats per min	-2.9680	29.552	-0.25044	0.983	0.929
EKG	heart rate, beats per min	-37.653	41.576	-2.2814	0.791	0.461
EKG	mean R amplitude, mean amplitude of signal measured from isoelectric line to peak of QRS	0.17907	0.20292	1.2603	0.781	0.471
EKG	mean SR amplitude, mean amplitude of signal measured from signal minimum line to peak of QRS	0.20441	0.28441	1.1098	0.811	0.547
EKG	number of signals	6.8720	6.2029	1.2388	0.832	0.383
EKG	proportion of number pairs of successive beat-to-beat intervals that exceed 50 ms	12.746	19.721	2.0821	0.896	0.584
EKG	QT dispersion, measured as inter-lead variability of QT intervals	2.3923	3.7231	0.72337	0.964	0.586
EKG	QTc dispersion, calculated as rate-corrected QT dispersion	0.79580	2.4641	0.21936	0.968	0.777
EKG	root mean square of successive differences of neighboring RR intervals	-1.6992	4.7614	-0.82678	0.947	0.755
glucose tolerance test	amount glucose injected	-2.5610	2.1128	-0.38391	0.619	0.233
glucose tolerance test	plasma glucose, 0min	-33.377	8.4240	-2.4799	0.00488	0.000298
glucose tolerance test	plasma glucose, 15min	-27.007	26.009	-0.62782	0.637	0.305
glucose tolerance test	plasma glucose, 30min	-10.817	26.803	-0.20739	0.869	0.689
glucose tolerance test	plasma glucose, 60min	15.842	20.996	0.73701	0.754	0.455
glucose tolerance test	plasma glucose, 120min	-1.1172	8.6036	-0.19338	0.959	0.897
grip strength	body weight (at time of grip strength test)	0.75147	0.43742	0.90448	0.236	0.0982
grip strength	forelimb and hindlimb grip strength (mean of trials), average	1.9649	9.3593	0.38548	0.913	0.835
grip strength	forelimb and hindlimb grip strength (mean of trials), average normalized to bw	0.060487	0.53696	0.27199	0.955	0.911
grip strength	forelimb and hindlimb grip strength by trial, trial1	14.266	13.701	1.2169	0.610	0.308
grip strength	forelimb and hindlimb grip strength by trial, trial2	3.6493	11.341	0.46013	0.883	0.750
grip strength	forelimb and hindlimb grip strength by trial, trial3	0.91176	12.449	0.26747	0.977	0.942
grip strength	forelimb grip strength (mean of trials), average	2.7674	4.9613	0.65008	0.796	0.582
grip strength	forelimb grip strength (mean of trials), average normalized to bw	0.00074226	0.22962	0.24496	0.999	0.997
grip strength	forelimb grip strength by trial, trial1	11.367	6.0947	1.4925	0.331	0.0740
grip strength	forelimb grip strength by trial, trial2	14.348	7.5827	1.7057	0.316	0.0701
grip strength	forelimb grip strength by trial, trial3	-18.914	6.6697	-1.5926	0.105	0.00913
heart weight	heart weight, normalized to body weight	-0.34207	0.21528	-1.7214	0.295	0.120
heart weight	heart weight, weight	-3.4154	3.6676	-0.82632	0.571	0.357
hematology	basophil differential (percent of total WBC)	-0.11667	0.062474	-1.4128	0.451	0.0720
hematology	calculated hemoglobin (cHGB)	-0.10539	0.17120	-0.60934	0.771	0.543
hematology	eosinophil differential (percent of total WBC)	-0.25013	0.26344	-0.61266	0.734	0.350
hematology	hematocrit (HCT)	0.93803	0.49495	0.70658	0.305	0.0681
hematology	hemoglobin concentration distribution width (HDW)	-0.031667	0.018370	-0.88040	0.365	0.0954
hematology	large unstained cells (percent of total WBC)	-0.059426	0.11815	-0.38541	0.844	0.619
hematology	lymphocyte differential (percent of total WBC)	-2.1238	1.5970	-0.94725	0.448	0.194
hematology	mean platelet volume (MPV)	0.15591	0.090828	0.77208	0.258	0.0967
hematology	mean RBC corpuscular hemoglobin (MCH)	-0.12399	0.084866	-0.49209	0.498	0.155
hematology	mean RBC corpuscular hemoglobin concentration (MCHC)	-0.65914	0.20557	-1.0353	0.0724	0.00326
hematology	mean RBC corpuscular volume (MCV)	0.48892	0.24299	0.85297	0.180	0.0536
hematology	measured hemoglobin (mHGB)	-0.025949	0.16682	-0.30625	0.947	0.877
hematology	monocyte differential (percent of total WBC)	0.36108	0.42180	1.2953	0.724	0.399
hematology	neutrophil differential (percent of total WBC)	2.4222	1.3989	1.1457	0.297	0.0940
hematology	platelet count (PLT; units per volume x 10³)	98.376	71.385	1.2922	0.558	0.179
hematology	RBC corpuscular distribution width (RDW)	-0.15512	0.11615	-0.56044	0.451	0.192
hematology	RBC corpuscular hemoglobin concentration mean (CHCM)	-0.79567	0.19262	-1.8339	0.00661	0.000280
hematology	red blood cell count (RBC; per volume x 10⁶)	0.094006	0.12661	0.068466	0.702	0.464
hematology	white blood cell count (WBC; units per volume x 10³)	-0.63287	0.51364	-0.27543	0.436	0.228
holeboard	number of hole pokes by individual hole number, 20 min test, 1	0.36831	1.4830	0.41964	0.943	0.806
holeboard	number of hole pokes by individual hole number, 20 min test, 2	-1.0266	0.53744	-1.4856	0.572	0.0706
holeboard	number of hole pokes by individual hole number, 20 min test, 3	-0.66151	0.67427	-1.0357	0.801	0.338
holeboard	number of hole pokes by individual hole number, 20 min test, 4	1.0903	1.1011	1.1491	0.763	0.334
holeboard	number of hole pokes by individual hole number, 20 min test, 5	-0.44738	0.70803	-0.63114	0.880	0.535
holeboard	number of hole pokes by individual hole number, 20 min test, 6	-0.30197	0.53667	-0.83252	0.930	0.580
holeboard	number of hole pokes by individual hole number, 20 min test, 7	-0.34561	0.42929	-0.96787	0.902	0.430
holeboard	number of hole pokes by individual hole number, 20 min test, 8	-0.67251	0.54652	-1.0045	0.754	0.233
holeboard	number of hole pokes by individual hole number, 20 min test, 9	-1.4603	0.58085	-2.1747	0.332	0.0206
holeboard	number of hole pokes by individual hole number, 20 min test, 10	-0.10588	0.36018	-0.21648	0.952	0.772
holeboard	number of hole pokes by individual hole number, 20 min test, 11	-0.060601	0.41617	-0.14748	0.978	0.886
holeboard	number of hole pokes by individual hole number, 20 min test, 12	-0.38610	0.47472	-0.57303	0.819	0.426
holeboard	number of hole pokes by individual hole number, 20 min test, 13	-2.5273	1.1823	-2.3761	0.396	0.0451
holeboard	number of hole pokes by individual hole number, 20 min test, 14	-1.3102	0.51018	-2.0102	0.321	0.0184
holeboard	number of hole pokes by individual hole number, 20 min test, 15	-0.77361	0.72532	-1.1463	0.747	0.299
holeboard	number of hole pokes by individual hole number, 20 min test, 16	-0.28549	1.1162	-0.22973	0.942	0.801
holeboard	total number of hole pokes, 20 min test	-8.4574	7.5433	-1.1238	0.564	0.275
light / dark	fecal boli count, 20 min test	0.30485	0.86185	0.37138	0.926	0.725
light / dark	latency to enter dark zone, 20 min test	28.443	28.204	0.43667	0.718	0.319
light / dark	number of transitions between light and dark zones, 20 min test	-5.5081	9.1116	-0.44263	0.794	0.549
light / dark	percentage of total time in dark zone, 20 min test	5.0106	3.9188	1.0275	0.584	0.208
light / dark	percentage of total time in light zone, 20 min test	-5.0106	3.9188	-1.0344	0.584	0.208
light / dark	time mobile in dark zone, 20 min test	-2.0444	13.186	-0.22913	0.953	0.878
light / dark	time mobile in light zone, 20 min test	-15.889	12.221	-1.3537	0.456	0.201
light / dark	time spent in dark zone, 20 min test	34.027	42.942	0.74851	0.789	0.433
light / dark	time spent in light zone, 20 min test	-34.027	42.942	-0.74851	0.789	0.433
open field	average speed in center of arena, 20 min test	-0.73700	0.53723	-1.4826	0.515	0.180
open field	average speed in periphery of arena, 20 min test	-0.19605	0.12759	-1.2596	0.321	0.135
open field	distance traveled habituation ratio, 20 min test	29.079	8.3437	2.0252	0.0371	0.00154
open field	distance traveled in center of arena, 20 min test	-171.28	80.340	-1.4100	0.172	0.0413
open field	distance traveled in periphery of arena, 20 min test	-152.40	145.97	-1.0481	0.548	0.305
open field	distance traveled slope, 20 min test	26.624	7.5889	2.0252	0.0326	0.00144
open field	distance traveled, 20 min test, 1st 5min	-250.24	66.842	-2.0357	0.0121	0.000768
open field	distance traveled, 20 min test, 2nd 5min	-60.013	47.514	-1.1859	0.449	0.216
open field	distance traveled, 20 min test, 3rd 5min	-46.437	48.684	-0.96778	0.609	0.348
open field	distance traveled, 20 min test, 4th 5min	23.480	57.364	-0.18430	0.846	0.685
open field	number of clockwise revolution episodes, 20 min test	0.86055	1.1146	0.091473	0.764	0.446
open field	number of counter-clockwise revolution episodes, 20 min test	-1.3833	1.0794	-1.1724	0.500	0.210
open field	number of fecal boli, 20 min test	0.75703	1.0033	0.80489	0.744	0.457
open field	number of rears in 5 min bins, 20 min test, 1st 5min	-9.0010	2.0166	-2.4072	0.00496	0.000105
open field	number of rears in 5 min bins, 20 min test, 2nd 5min	-6.2675	2.4321	-1.7805	0.111	0.0151
open field	number of rears in 5 min bins, 20 min test, 3rd 5min	-5.1104	2.6186	-1.4588	0.245	0.0604
open field	number of rears in 5 min bins, 20 min test, 4th 5min	-4.4912	3.7427	-1.2898	0.513	0.240
open field	percentage of total time in center of arena, 20 min test	-2.3826	2.4454	-0.78627	0.654	0.338
open field	percentage of total time in center of arena, slope, 20 min test	-0.70023	1.3260	-0.26001	0.896	0.601
open field	percentage of total time in center, habituation ratio, 20 min test	-1.0000	1.3388	-0.41360	0.845	0.461
open field	percentage of total time in corners of arena, 20 min test	8.1527	5.1034	1.6955	0.416	0.121
open field	percentage of total time in corners, habituation ratio, 20 min test	-2.3589	2.2373	-1.4100	0.787	0.300
open field	percentage of total time in corners, slope, 20 min test	-2.0080	2.2324	-1.2420	0.817	0.376
open field	permanence time in center of arena, 20 min test	-28.598	29.347	-0.78627	0.654	0.338
open field	permanence time in corners of arena, 20 min test	97.822	61.242	1.6955	0.417	0.121
open field	permanence time in periphery of arena, 20 min test	28.584	29.342	0.78627	0.654	0.338
open field	total distance traveled, 20 min test	-353.71	171.85	-1.4666	0.163	0.0483
open field	total number of rears, 20 min test	-23.736	8.8776	-1.9050	0.0843	0.0120
open field	whole arena average speed, 20 min test	-0.29714	0.14305	-1.4785	0.160	0.0464
open field	whole arena resting time, 20 min test	22.173	17.481	1.1698	0.407	0.214
open field	whole arena time spent mobile, 20 min test	-22.068	17.470	-1.3815	0.414	0.216
open field	whole arena time spent vertical, 20 min test	-24.133	10.125	-1.7805	0.180	0.0237
SHIRPA	locomotor activity (number of squares in the arena the mouse moves into with all four paws in first 30 s of test)	-1.9973	2.0854	-0.66573	0.648	0.347
startle / PPI	average baseline movement during background noise	-0.12390	1.1841	-0.014712	0.995	0.917
startle / PPI	average of each corrected maximum percent pre-pulse inhibition value	0.092614	0.079124	0.76952	0.612	0.249
startle / PPI	average of each corrected percent pre-pulse inhibition value	0.10359	0.074407	0.91677	0.517	0.172
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	13.837	7.9686	1.6365	0.817	0.0902
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	5.8575	7.2353	0.52875	0.736	0.423
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	7.5434	6.7013	0.67669	0.567	0.267
startle / PPI	average startle response to full pulse (120 dB)	27.817	23.795	0.76388	0.492	0.249
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	0.95772	18.801	0.20530	0.982	0.960
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	6.7741	20.308	0.32879	0.851	0.740
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	11.552	16.359	0.47785	0.674	0.484
startle / PPI	average startle response to pre-pulse, 74dB sound pressure level	-2.8615	1.2564	-1.8237	0.492	0.0282
startle / PPI	average startle response to pre-pulse, 78dB sound pressure level	1.7873	1.1808	0.96110	0.639	0.138
startle / PPI	average startle response to pre-pulse, 82dB sound pressure level	2.4464	1.4845	0.87360	0.530	0.107
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	0.13624	0.092054	1.3547	0.809	0.147
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	0.075317	0.081702	0.55540	0.680	0.362
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	0.099362	0.079159	0.59391	0.476	0.217
startle / PPI	corrected average startle response to full pulse (120 dB) minus average baseline movement during background noise	27.941	23.821	0.77518	0.488	0.248
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 74dB sound pressure level	3.8246	18.715	0.28473	0.927	0.839
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 78dB sound pressure level	4.9009	20.363	0.28035	0.890	0.811
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 82dB sound pressure level	9.0926	16.705	0.43740	0.756	0.589
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	0.13777	0.096288	1.2141	0.804	0.160
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	0.050225	0.085922	0.30760	0.795	0.562
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	0.090032	0.089914	0.48522	0.587	0.323
startle / PPI	corrected maximum startle response to full pulse (120 dB) minus maximum baseline movement during background noise	86.080	89.165	0.68022	0.580	0.340
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 74dB sound pressure level	1.8579	68.995	0.19101	0.992	0.979
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 78dB sound pressure level	24.526	74.748	0.31109	0.847	0.745
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 82dB sound pressure level	35.879	62.876	0.43278	0.738	0.571
startle / PPI	maximum baseline movement during background noise	-1.9180	3.1245	-0.52392	0.867	0.543
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	13.869	8.6187	1.4603	0.797	0.115
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	4.2066	7.9612	0.29203	0.833	0.600
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	7.1367	7.8225	0.53682	0.655	0.367
startle / PPI	maximum startle response to full pulse (120 dB)	85.738	89.000	0.67493	0.581	0.341
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-6.8400	69.382	0.15261	0.958	0.922
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	27.107	74.583	0.32288	0.834	0.718
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	41.160	62.285	0.45753	0.695	0.513
startle / PPI	maximum startle response to pre-pulse, 74dB sound pressure level	-8.6925	3.0452	-2.0870	0.305	0.00680
startle / PPI	maximum startle response to pre-pulse, 78dB sound pressure level	2.6694	2.5723	0.72688	0.770	0.306
startle / PPI	maximum startle response to pre-pulse, 82dB sound pressure level	5.2536	3.6007	0.71416	0.519	0.152

MULTIPLE (CATEGORICAL) TRAIT PROFILE PLOT — Early Adult Phenotyping study (EAP)

Procedure	JaxKOMP-EAP Trait	Sex	Trait Effect	P-value
eye morphology	anterior chamber depth	females	1.0 %	1.0
eye morphology	anterior chamber depth	males	0.0 %	1.0
eye morphology	anterior chamber depth	both	1.0 %	1.0
eye morphology	bulging eye	females	1.0 %	1.0
eye morphology	bulging eye	males	0.0 %	1.0
eye morphology	bulging eye	both	1.0 %	1.00
eye morphology	cornea	females	4.0 %	1.0
eye morphology	cornea	males	2.0 %	1.0
eye morphology	cornea	both	3.0 %	1.00
eye morphology	cornea opacity	females	5.0 %	1.0
eye morphology	cornea opacity	males	1.0 %	1.0
eye morphology	cornea opacity	both	3.0 %	1.00
eye morphology	cornea vascularization	females	3.0 %	1.0
eye morphology	cornea vascularization	males	1.0 %	1.0
eye morphology	cornea vascularization	both	2.0 %	1.00
eye morphology	corneal deposits	females	2.0 %	1.0
eye morphology	corneal deposits	males	1.0 %	1.0
eye morphology	corneal deposits	both	1.0 %	1.00
eye morphology	corneal mineralization	females	2.0 %	1.0
eye morphology	corneal mineralization	males	1.0 %	1.0
eye morphology	corneal mineralization	both	1.0 %	1.00
eye morphology	corneal scleralization	females	3.0 %	1.0
eye morphology	corneal scleralization	males	1.0 %	1.0
eye morphology	corneal scleralization	both	2.0 %	1.00
eye morphology	corneal ulcer	females	1.0 %	1.0
eye morphology	corneal ulcer	males	1.0 %	1.0
eye morphology	corneal ulcer	both	1.0 %	1.00
eye morphology	eye closure	females	1.0 %	1.0
eye morphology	eye closure	males	0.0 %	1.0
eye morphology	eye closure	both	1.0 %	1.00
eye morphology	eye hemorrhage or blood presence	females	2.0 %	1.0
eye morphology	eye hemorrhage or blood presence	males	1.0 %	1.0
eye morphology	eye hemorrhage or blood presence	both	1.0 %	1.00
eye morphology	eyelid morphology	females	1.0 %	1.00
eye morphology	eyelid morphology	males	0.0 %	1.0
eye morphology	eyelid morphology	both	1.0 %	1.00
eye morphology	eyes (present, absent)	females	1.0 %	1.00
eye morphology	eyes (present, absent)	males	0.0 %	1.0
eye morphology	eyes (present, absent)	both	0.0 %	1.00
eye morphology	fusion between cornea and lens	females	4.0 %	1.0
eye morphology	fusion between cornea and lens	males	2.0 %	1.0
eye morphology	fusion between cornea and lens	both	3.0 %	1.00
eye morphology	iris pigmentation	females	2.0 %	1.0
eye morphology	iris pigmentation	males	1.0 %	1.0
eye morphology	iris pigmentation	both	2.0 %	1.00
eye morphology	iris transillumination	females	2.0 %	1.0
eye morphology	iris transillumination	males	1.0 %	1.00
eye morphology	iris transillumination	both	1.0 %	1.00
eye morphology	irispupil	females	4.0 %	1.0
eye morphology	irispupil	males	3.0 %	1.0
eye morphology	irispupil	both	3.0 %	1.00
eye morphology	lacrimation	females	3.0 %	1.0
eye morphology	lacrimation	males	2.0 %	1.0
eye morphology	lacrimation	both	3.0 %	1.00
eye morphology	lens	females	10.0 %	1.0
eye morphology	lens	males	8.0 %	1.00
eye morphology	lens	both	9.0 %	1.00
eye morphology	lens opacity	females	37.0 %	0.0582
eye morphology	lens opacity	males	6.0 %	1.0
eye morphology	lens opacity	both	17.0 %	0.150
eye morphology	narrow eye opening	females	2.0 %	1.00
eye morphology	narrow eye opening	males	1.0 %	1.0
eye morphology	narrow eye opening	both	1.0 %	1.00
eye morphology	optic disc	females	4.0 %	1.0
eye morphology	optic disc	males	2.0 %	1.0
eye morphology	optic disc	both	3.0 %	1.00
eye morphology	persistence of hyaloid vascular system	females	14.0 %	1.0
eye morphology	persistence of hyaloid vascular system	males	38.0 %	0.0182
eye morphology	persistence of hyaloid vascular system	both	16.0 %	0.302
eye morphology	pupil dilation	females	2.0 %	1.0
eye morphology	pupil dilation	males	1.0 %	1.0
eye morphology	pupil dilation	both	2.0 %	1.00
eye morphology	pupil light response	females	2.0 %	1.0
eye morphology	pupil light response	males	1.0 %	1.0
eye morphology	pupil light response	both	2.0 %	1.00
eye morphology	pupil position	females	4.0 %	1.0
eye morphology	pupil position	males	3.0 %	1.0
eye morphology	pupil position	both	4.0 %	1.00
eye morphology	pupil shape	females	3.0 %	1.0
eye morphology	pupil shape	males	2.0 %	1.0
eye morphology	pupil shape	both	3.0 %	1.00
eye morphology	retina	females	30.0 %	0.0381
eye morphology	retina	males	84.0 %	0.000151
eye morphology	retina	both	57.0 %	0.0000458
eye morphology	retinal blood vessels	females	4.0 %	1.0
eye morphology	retinal blood vessels	males	2.0 %	1.0
eye morphology	retinal blood vessels	both	3.0 %	1.00
eye morphology	retinal blood vessels pattern	females	5.0 %	1.0
eye morphology	retinal blood vessels pattern	males	2.0 %	1.00
eye morphology	retinal blood vessels pattern	both	4.0 %	1.00
eye morphology	retinal blood vessels structure	females	4.0 %	1.0
eye morphology	retinal blood vessels structure	males	2.0 %	1.0
eye morphology	retinal blood vessels structure	both	3.0 %	1.00
eye morphology	retinal pigmentation	females	58.0 %	0.00207
eye morphology	retinal pigmentation	males	26.0 %	0.145
eye morphology	retinal pigmentation	both	37.0 %	0.00443
eye morphology	retinal structure	females	4.0 %	1.0
eye morphology	retinal structure	males	2.0 %	1.00
eye morphology	retinal structure	both	3.0 %	1.00
eye morphology	synechia	females	4.0 %	1.0
eye morphology	synechia	males	2.0 %	1.0
eye morphology	synechia	both	3.0 %	1.00
eye morphology	vitreous	females	4.0 %	1.0
eye morphology	vitreous	males	2.0 %	1.0
eye morphology	vitreous	both	3.0 %	1.00
SHIRPA	activity body position	females	1.0 %	1.0
SHIRPA	activity body position	males	2.0 %	1.0
SHIRPA	activity body position	both	1.0 %	1.00
SHIRPA	aggression	females	0.0 %	1.0
SHIRPA	aggression	males	1.0 %	1.0
SHIRPA	aggression	both	1.0 %	1.00
SHIRPA	body length	females	0.0 %	1.0
SHIRPA	body length	males	0.0 %	1.00
SHIRPA	body length	both	0.0 %	1.0
SHIRPA	body position	females	0.0 %	1.0
SHIRPA	body position	males	1.0 %	1.0
SHIRPA	body position	both	0.0 %	1.00
SHIRPA	body thickness	females	1.0 %	1.0
SHIRPA	body thickness	males	0.0 %	1.0
SHIRPA	body thickness	both	0.0 %	1.00
SHIRPA	coat color abdomen	females	3.0 %	1.0
SHIRPA	coat color abdomen	males	4.0 %	1.0
SHIRPA	coat color abdomen	both	4.0 %	1.00
SHIRPA	coat color back	females	0.0 %	1.0
SHIRPA	coat color back	males	0.0 %	1.00
SHIRPA	coat color back	both	0.0 %	1.00
SHIRPA	coat color head	females	0.0 %	1.0
SHIRPA	coat color head	males	0.0 %	1.00
SHIRPA	coat color head	both	0.0 %	1.0
SHIRPA	coat color pattern abdomen	females	1.0 %	1.0
SHIRPA	coat color pattern abdomen	males	1.0 %	1.0
SHIRPA	coat color pattern abdomen	both	1.0 %	1.00
SHIRPA	coat color pattern back	females	0.0 %	1.0
SHIRPA	coat color pattern back	males	0.0 %	1.00
SHIRPA	coat color pattern back	both	0.0 %	1.00
SHIRPA	coat color pattern head	females	0.0 %	1.0
SHIRPA	coat color pattern head	males	0.0 %	1.0
SHIRPA	coat color pattern head	both	0.0 %	1.0
SHIRPA	coat hair abdomen texture appearance	females	2.0 %	1.0
SHIRPA	coat hair abdomen texture appearance	males	2.0 %	1.0
SHIRPA	coat hair abdomen texture appearance	both	2.0 %	1.0
SHIRPA	coat hair back texture appearance	females	0.0 %	1.0
SHIRPA	coat hair back texture appearance	males	0.0 %	1.0
SHIRPA	coat hair back texture appearance	both	0.0 %	1.0
SHIRPA	coat hair distribution abdomen	females	0.0 %	1.0
SHIRPA	coat hair distribution abdomen	males	1.0 %	1.00
SHIRPA	coat hair distribution abdomen	both	1.0 %	1.0
SHIRPA	coat hair distribution back	females	0.0 %	1.0
SHIRPA	coat hair distribution back	males	0.0 %	1.0
SHIRPA	coat hair distribution back	both	0.0 %	1.00
SHIRPA	coat hair distribution head	females	1.0 %	1.00
SHIRPA	coat hair distribution head	males	1.0 %	1.0
SHIRPA	coat hair distribution head	both	1.0 %	1.0
SHIRPA	coat hair head texture appearance	females	0.0 %	1.0
SHIRPA	coat hair head texture appearance	males	0.0 %	1.0
SHIRPA	coat hair head texture appearance	both	0.0 %	1.0
SHIRPA	contact righting	females	5.0 %	1.0
SHIRPA	contact righting	males	5.0 %	1.00
SHIRPA	contact righting	both	5.0 %	1.00
SHIRPA	ear morphology	females	0.0 %	1.0
SHIRPA	ear morphology	males	0.0 %	1.0
SHIRPA	ear morphology	both	0.0 %	1.0
SHIRPA	fat distribution	females	0.0 %	1.0
SHIRPA	fat distribution	males	0.0 %	1.0
SHIRPA	fat distribution	both	0.0 %	1.0
SHIRPA	forelimb digit number	females	0.0 %	1.0
SHIRPA	forelimb digit number	males	0.0 %	1.0
SHIRPA	forelimb digit number	both	0.0 %	1.0
SHIRPA	forelimb digit position	females	0.0 %	1.0
SHIRPA	forelimb digit position	males	0.0 %	1.0
SHIRPA	forelimb digit position	both	0.0 %	1.0
SHIRPA	forelimb digit shape	females	0.0 %	1.0
SHIRPA	forelimb digit shape	males	0.0 %	1.0
SHIRPA	forelimb digit shape	both	0.0 %	1.0
SHIRPA	forelimb digit size	females	0.0 %	1.0
SHIRPA	forelimb digit size	males	0.0 %	1.0
SHIRPA	forelimb digit size	both	0.0 %	1.0
SHIRPA	forelimb footpads	females	0.0 %	1.0
SHIRPA	forelimb footpads	males	0.0 %	1.0
SHIRPA	forelimb footpads	both	0.0 %	1.0
SHIRPA	forelimb nail length	females	0.0 %	1.0
SHIRPA	forelimb nail length	males	0.0 %	1.0
SHIRPA	forelimb nail length	both	0.0 %	1.0
SHIRPA	forelimb nail number	females	0.0 %	1.0
SHIRPA	forelimb nail number	males	0.0 %	1.0
SHIRPA	forelimb nail number	both	0.0 %	1.0
SHIRPA	forelimb nail position	females	0.0 %	1.0
SHIRPA	forelimb nail position	males	0.0 %	1.0
SHIRPA	forelimb nail position	both	0.0 %	1.0
SHIRPA	forelimb nail shape	females	0.0 %	1.0
SHIRPA	forelimb nail shape	males	0.0 %	1.0
SHIRPA	forelimb nail shape	both	0.0 %	1.0
SHIRPA	forelimbs position	females	0.0 %	1.0
SHIRPA	forelimbs position	males	0.0 %	1.0
SHIRPA	forelimbs position	both	0.0 %	1.0
SHIRPA	forelimbs shape	females	0.0 %	1.0
SHIRPA	forelimbs shape	males	0.0 %	1.0
SHIRPA	forelimbs shape	both	0.0 %	1.0
SHIRPA	forelimbs size	females	0.0 %	1.0
SHIRPA	forelimbs size	males	0.0 %	1.0
SHIRPA	forelimbs size	both	0.0 %	1.0
SHIRPA	forepaw position	females	0.0 %	1.0
SHIRPA	forepaw position	males	0.0 %	1.0
SHIRPA	forepaw position	both	0.0 %	1.0
SHIRPA	forepaw shape	females	0.0 %	1.0
SHIRPA	forepaw shape	males	0.0 %	1.0
SHIRPA	forepaw shape	both	0.0 %	1.0
SHIRPA	forepaw size	females	0.0 %	1.0
SHIRPA	forepaw size	males	0.0 %	1.0
SHIRPA	forepaw size	both	0.0 %	1.0
SHIRPA	gait (fluidity)	females	0.0 %	1.0
SHIRPA	gait (fluidity)	males	0.0 %	1.00
SHIRPA	gait (fluidity)	both	0.0 %	1.0
SHIRPA	genitalia morphology	females	0.0 %	1.0
SHIRPA	genitalia morphology	males	0.0 %	1.0
SHIRPA	genitalia morphology	both	0.0 %	1.00
SHIRPA	genitalia presence	females	0.0 %	1.0
SHIRPA	genitalia presence	males	0.0 %	1.0
SHIRPA	genitalia presence	both	0.0 %	1.0
SHIRPA	genitalia size	females	0.0 %	1.0
SHIRPA	genitalia size	males	0.0 %	1.0
SHIRPA	genitalia size	both	0.0 %	1.00
SHIRPA	head bobbing	females	0.0 %	1.0
SHIRPA	head bobbing	males	0.0 %	1.0
SHIRPA	head bobbing	both	0.0 %	1.0
SHIRPA	head morphology	females	0.0 %	1.0
SHIRPA	head morphology	males	0.0 %	1.00
SHIRPA	head morphology	both	0.0 %	1.0
SHIRPA	head size	females	0.0 %	1.0
SHIRPA	head size	males	0.0 %	1.0
SHIRPA	head size	both	0.0 %	1.0
SHIRPA	hindlimb digit number	females	1.0 %	1.0
SHIRPA	hindlimb digit number	males	0.0 %	1.0
SHIRPA	hindlimb digit number	both	0.0 %	1.0
SHIRPA	hindlimb digit position	females	0.0 %	1.0
SHIRPA	hindlimb digit position	males	0.0 %	1.0
SHIRPA	hindlimb digit position	both	0.0 %	1.0
SHIRPA	hindlimb digit shape	females	0.0 %	1.0
SHIRPA	hindlimb digit shape	males	0.0 %	1.0
SHIRPA	hindlimb digit shape	both	0.0 %	1.00
SHIRPA	hindlimb digit size	females	0.0 %	1.0
SHIRPA	hindlimb digit size	males	0.0 %	1.0
SHIRPA	hindlimb digit size	both	0.0 %	1.00
SHIRPA	hindlimb nail length	females	0.0 %	1.0
SHIRPA	hindlimb nail length	males	0.0 %	1.0
SHIRPA	hindlimb nail length	both	0.0 %	1.0
SHIRPA	hindlimb nail number	females	0.0 %	1.0
SHIRPA	hindlimb nail number	males	1.0 %	1.0
SHIRPA	hindlimb nail number	both	0.0 %	1.0
SHIRPA	hindlimb nail position	females	0.0 %	1.0
SHIRPA	hindlimb nail position	males	0.0 %	1.0
SHIRPA	hindlimb nail position	both	0.0 %	1.0
SHIRPA	hindlimb nail shape	females	0.0 %	1.0
SHIRPA	hindlimb nail shape	males	0.0 %	1.0
SHIRPA	hindlimb nail shape	both	0.0 %	1.0
SHIRPA	hindlimbs footpads	females	0.0 %	1.0
SHIRPA	hindlimbs footpads	males	0.0 %	1.0
SHIRPA	hindlimbs footpads	both	0.0 %	1.0
SHIRPA	hindlimbs position	females	0.0 %	1.0
SHIRPA	hindlimbs position	males	0.0 %	1.0
SHIRPA	hindlimbs position	both	0.0 %	1.0
SHIRPA	hindlimbs shape	females	0.0 %	1.0
SHIRPA	hindlimbs shape	males	0.0 %	1.0
SHIRPA	hindlimbs shape	both	0.0 %	1.0
SHIRPA	hindlimbs size	females	0.0 %	1.0
SHIRPA	hindlimbs size	males	0.0 %	1.0
SHIRPA	hindlimbs size	both	0.0 %	1.0
SHIRPA	hindpaw position	females	0.0 %	1.0
SHIRPA	hindpaw position	males	0.0 %	1.0
SHIRPA	hindpaw position	both	0.0 %	1.0
SHIRPA	hindpaw shape	females	0.0 %	1.0
SHIRPA	hindpaw shape	males	0.0 %	1.0
SHIRPA	hindpaw shape	both	0.0 %	1.0
SHIRPA	hindpaw size	females	0.0 %	1.0
SHIRPA	hindpaw size	males	0.0 %	1.0
SHIRPA	hindpaw size	both	0.0 %	1.0
SHIRPA	limb grasp	females	9.0 %	1.0
SHIRPA	limb grasp	males	7.0 %	0.375
SHIRPA	limb grasp	both	1.0 %	1.0
SHIRPA	lower lip morphology	females	0.0 %	1.0
SHIRPA	lower lip morphology	males	0.0 %	1.0
SHIRPA	lower lip morphology	both	0.0 %	1.0
SHIRPA	lower teeth appearance	females	0.0 %	1.0
SHIRPA	lower teeth appearance	males	0.0 %	1.00
SHIRPA	lower teeth appearance	both	0.0 %	1.0
SHIRPA	mouth morphology	females	0.0 %	1.0
SHIRPA	mouth morphology	males	0.0 %	1.00
SHIRPA	mouth morphology	both	0.0 %	1.0
SHIRPA	salivation	females	0.0 %	1.0
SHIRPA	salivation	males	0.0 %	1.0
SHIRPA	salivation	both	0.0 %	1.0
SHIRPA	skin color back paws	females	0.0 %	1.0
SHIRPA	skin color back paws	males	0.0 %	1.0
SHIRPA	skin color back paws	both	0.0 %	1.0
SHIRPA	skin color ear	females	0.0 %	1.0
SHIRPA	skin color ear	males	0.0 %	1.0
SHIRPA	skin color ear	both	0.0 %	1.0
SHIRPA	skin color front paws	females	0.0 %	1.0
SHIRPA	skin color front paws	males	0.0 %	1.0
SHIRPA	skin color front paws	both	0.0 %	1.0
SHIRPA	skin color snout	females	0.0 %	1.0
SHIRPA	skin color snout	males	0.0 %	1.0
SHIRPA	skin color snout	both	0.0 %	1.0
SHIRPA	skin color tail	females	0.0 %	1.0
SHIRPA	skin color tail	males	0.0 %	1.0
SHIRPA	skin color tail	both	0.0 %	1.0
SHIRPA	skin color whole body	females	0.0 %	1.0
SHIRPA	skin color whole body	males	0.0 %	1.0
SHIRPA	skin color whole body	both	0.0 %	1.0
SHIRPA	skin texture back paw	females	0.0 %	1.0
SHIRPA	skin texture back paw	males	0.0 %	1.0
SHIRPA	skin texture back paw	both	0.0 %	1.0
SHIRPA	skin texture ear	females	0.0 %	1.0
SHIRPA	skin texture ear	males	0.0 %	1.0
SHIRPA	skin texture ear	both	0.0 %	1.0
SHIRPA	skin texture front paws	females	0.0 %	1.0
SHIRPA	skin texture front paws	males	0.0 %	1.0
SHIRPA	skin texture front paws	both	0.0 %	1.0
SHIRPA	skin texture snout	females	0.0 %	1.0
SHIRPA	skin texture snout	males	0.0 %	1.0
SHIRPA	skin texture snout	both	0.0 %	1.0
SHIRPA	skin texture tail	females	0.0 %	1.0
SHIRPA	skin texture tail	males	0.0 %	1.0
SHIRPA	skin texture tail	both	0.0 %	1.0
SHIRPA	skin texture whole body	females	0.0 %	1.0
SHIRPA	skin texture whole body	males	0.0 %	1.00
SHIRPA	skin texture whole body	both	0.0 %	1.00
SHIRPA	snout size	females	0.0 %	1.0
SHIRPA	snout size	males	1.0 %	1.0
SHIRPA	snout size	both	0.0 %	1.0
SHIRPA	startle response	females	0.0 %	1.0
SHIRPA	startle response	males	0.0 %	1.00
SHIRPA	startle response	both	0.0 %	1.0
SHIRPA	tail curvature	females	0.0 %	1.00
SHIRPA	tail curvature	males	0.0 %	1.0
SHIRPA	tail curvature	both	0.0 %	1.00
SHIRPA	tail elevation	females	1.0 %	1.0
SHIRPA	tail elevation	males	2.0 %	1.0
SHIRPA	tail elevation	both	1.0 %	1.0
SHIRPA	tail length	females	0.0 %	1.0
SHIRPA	tail length	males	0.0 %	1.0
SHIRPA	tail length	both	0.0 %	1.0
SHIRPA	tail morphology	females	0.0 %	1.0
SHIRPA	tail morphology	males	0.0 %	1.0
SHIRPA	tail morphology	both	0.0 %	1.00
SHIRPA	tail presence	females	0.0 %	1.0
SHIRPA	tail presence	males	0.0 %	1.0
SHIRPA	tail presence	both	0.0 %	1.0
SHIRPA	tail shape	females	0.0 %	1.0
SHIRPA	tail shape	males	0.0 %	1.0
SHIRPA	tail shape	both	0.0 %	1.0
SHIRPA	tail thickness	females	0.0 %	1.0
SHIRPA	tail thickness	males	0.0 %	1.0
SHIRPA	tail thickness	both	0.0 %	1.0
SHIRPA	teeth presence	females	0.0 %	1.0
SHIRPA	teeth presence	males	0.0 %	1.00
SHIRPA	teeth presence	both	0.0 %	1.0
SHIRPA	transfer arousal	females	1.0 %	1.0
SHIRPA	transfer arousal	males	2.0 %	1.00
SHIRPA	transfer arousal	both	1.0 %	1.0
SHIRPA	tremor	females	0.0 %	1.0
SHIRPA	tremor	males	0.0 %	1.0
SHIRPA	tremor	both	0.0 %	1.00
SHIRPA	trunk curl	females	0.0 %	1.0
SHIRPA	trunk curl	males	0.0 %	1.0
SHIRPA	trunk curl	both	0.0 %	1.00
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	females	0.0 %	1.0
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	males	0.0 %	1.0
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	both	0.0 %	1.0
SHIRPA	upper lip morphology	females	0.0 %	1.0
SHIRPA	upper lip morphology	males	0.0 %	1.0
SHIRPA	upper lip morphology	both	0.0 %	1.0
SHIRPA	upper teeth appearance	females	0.0 %	1.0
SHIRPA	upper teeth appearance	males	0.0 %	1.0
SHIRPA	upper teeth appearance	both	0.0 %	1.0
SHIRPA	vibrissae appearance	females	2.0 %	1.0
SHIRPA	vibrissae appearance	males	1.0 %	1.0
SHIRPA	vibrissae appearance	both	1.0 %	1.0
SHIRPA	vibrissae presence	females	2.0 %	1.00
SHIRPA	vibrissae presence	males	1.0 %	1.0
SHIRPA	vibrissae presence	both	2.0 %	1.0
SHIRPA	vocalization	females	2.0 %	1.0
SHIRPA	vocalization	males	2.0 %	1.0
SHIRPA	vocalization	both	2.0 %	1.0

GENOTYPE CORRELATION PLOT

Correlate Coq8b^{tm1b(EUCOMM)Hmgu} -/+ with genotype: