MPD: JaxKOMP-EAP genotype: Stxbp1<sup>tm1b(EUCOMM)Hmgu</sup> -/+

JaxKOMP-EAP effect sizes: Stxbp1^{tm1b(EUCOMM)Hmgu} -/+ Gene Stxbp1

MULTIPLE (NUMERIC) TRAIT PROFILE PLOT — Early Adult Phenotyping study (EAP)

Procedure	JaxKOMP-EAP Trait	Trait Effect	Trait Effect SE	Trait Effect RankZ	Adjusted p-value	Unadjusted p-value
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 6 kHz pip	6.3542	1.8414	1.3755	0.428	0.0747
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 12 kHz pip	4.3403	2.9651	0.91197	0.727	0.281
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 18 kHz pip	10.322	4.6065	1.4532	0.512	0.154
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 24 kHz pip	14.767	7.4593	1.9187	0.577	0.186
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 30 kHz pip	6.9718	4.1810	1.0686	0.631	0.237
body composition	body length	0.044821	0.050164	0.82994	0.665	0.377
body composition	body weight (at time of DXA)	-3.3810	0.67485	-1.8283	0.000269	0.00000933
body composition	bone area, whole body scan, head excluded	-0.35423	0.19948	-1.1103	0.293	0.0828
body composition	bone mineral content of whole body scan, head excluded	-0.014152	0.014671	-0.63557	0.630	0.340
body composition	bone mineral content to body weight ratio	-0.00041940	0.00059643	-0.35695	0.723	0.486
body composition	bone mineral density of whole body scan, head excluded	0.00034114	0.00073674	0.38569	0.831	0.646
body composition	fat tissue mass of whole body scan, head excluded	0.55745	0.48195	0.82846	0.501	0.254
body composition	fat tissue mass to body weight ratio	0.0089059	0.015761	0.46849	0.771	0.575
body composition	lean tissue mass of whole body scan, head excluded	-0.078792	0.35456	-0.32223	0.930	0.825
body composition	lean tissue mass to body weight ratio	-0.014213	0.012730	-0.81849	0.529	0.270
body composition	percent fat, whole body scan, head excluded	0.92201	1.4999	0.50383	0.744	0.542
body composition	ratio of soft-tissue attenuation coefficients	-0.0010104	0.0016648	-0.50503	0.753	0.547
body composition	tissue area	-0.061375	0.26134	-0.027339	0.943	0.815
body composition	total tissue mass, whole body scan, head excluded	0.44014	0.28331	0.70742	0.342	0.128
clinical blood chemistry	alanine transaminase (plasma ALT)	10.896	9.5246	0.79178	0.635	0.267
clinical blood chemistry	albumin (plasma Alb)	-0.35900	0.39736	-0.45274	0.685	0.378
clinical blood chemistry	alkaline phosphatase (plasma ALP)	10.564	3.5899	1.1900	0.0638	0.00870
clinical blood chemistry	aspartate transaminase (plasma AST)	-22.243	22.991	-1.0106	0.665	0.346
clinical blood chemistry	aspartate transaminase to alanine transaminase ratio (plasma AST:ALT)	0.11433	0.43675	0.39466	0.933	0.796
clinical blood chemistry	blood urea nitrogen (BUN)	2.9055	1.5752	1.1113	0.277	0.0808
clinical blood chemistry	calcium (plasma Ca)	-0.15379	0.071165	-0.77001	0.178	0.0437
clinical blood chemistry	creatinine (plasma)	-0.011713	0.025385	-0.19427	0.817	0.650
clinical blood chemistry	glucose (plasma GLU, no fast)	-14.595	11.301	-0.27999	0.411	0.212
clinical blood chemistry	HDL cholesterol (plasma HDL)	-5.6581	2.6215	-1.4303	0.228	0.0447
clinical blood chemistry	HDL cholesterol to total cholesterol ratio	0.011543	0.011887	0.47967	0.661	0.344
clinical blood chemistry	phosphorus (plasma phosphate)	0.46454	0.46455	0.64745	0.620	0.330
clinical blood chemistry	total bilirubin (plasma TBIL)	-0.0025093	0.012227	-0.18414	0.945	0.840
clinical blood chemistry	total cholesterol (plasma CHOL, no fast)	-13.938	3.6459	-2.1333	0.0277	0.00115
clinical blood chemistry	total protein (plasma TP)	-0.020016	0.67523	-0.072865	0.990	0.977
clinical blood chemistry	triglyceride (plasma TG, no fast)	9.4842	13.400	0.72196	0.736	0.488
EKG	duration of PQ interval	-0.74676	1.0026	-0.64692	0.889	0.461
EKG	duration of PR interval	-0.67469	1.0123	-0.59319	0.909	0.510
EKG	duration of QRS interval	0.63857	0.30713	1.5591	0.885	0.0452
EKG	duration of QT interval	0.55572	1.1733	0.68719	0.914	0.639
EKG	duration of QTC interval, calculated by dividing QT interval by square root of preceding RR interval	0.30857	0.64390	0.39925	0.939	0.635
EKG	duration of RR interval	2.6940	2.9121	1.5798	0.760	0.361
EKG	duration of ST interval	0.090673	1.0722	0.28175	0.980	0.933
EKG	heart rate coefficient of variation (signal intensity)	1.7597	1.0529	1.4644	0.807	0.104
EKG	heart rate variability, mean of differences between sequential beats; beats per min	12.701	6.8911	1.4763	0.761	0.0740
EKG	heart rate, beats per min	-19.663	21.231	-1.4465	0.738	0.361
EKG	number of signals	-1.7699	5.5338	-0.41457	0.948	0.751
EKG	proportion of number pairs of successive beat-to-beat intervals that exceed 50 ms	6.3277	7.0776	1.2419	0.846	0.378
EKG	QT dispersion, measured as inter-lead variability of QT intervals	3.4564	2.8481	0.98146	0.881	0.233
EKG	QTc dispersion, calculated as rate-corrected QT dispersion	2.8762	2.8506	0.76861	0.892	0.320
EKG	root mean square of successive differences of neighboring RR intervals	1.9410	1.9866	1.0666	0.860	0.335
glucose tolerance test	amount glucose injected	-0.86753	3.0821	0.088804	0.928	0.780
glucose tolerance test	plasma glucose, 0min	5.9113	5.8415	0.37072	0.539	0.319
glucose tolerance test	plasma glucose, 15min	81.087	19.236	2.0953	0.0151	0.000182
glucose tolerance test	plasma glucose, 30min	132.48	24.418	2.7776	0.000799	0.00000525
glucose tolerance test	plasma glucose, 60min	48.821	16.112	1.8184	0.0790	0.00473
glucose tolerance test	plasma glucose, 120min	59.946	11.481	2.5808	0.00147	0.0000104
grip strength	body weight (at time of grip strength test)	-2.8244	0.61703	-1.9055	0.00115	0.0000676
grip strength	forelimb and hindlimb grip strength (mean of trials), average	-2.6907	12.799	0.039222	0.913	0.835
grip strength	forelimb and hindlimb grip strength (mean of trials), average normalized to bw	0.71492	0.75442	1.2230	0.557	0.351
grip strength	forelimb and hindlimb grip strength by trial, trial1	-1.4786	10.434	0.13254	0.958	0.888
grip strength	forelimb and hindlimb grip strength by trial, trial2	15.851	13.248	1.1929	0.493	0.241
grip strength	forelimb and hindlimb grip strength by trial, trial3	25.090	15.152	1.7928	0.329	0.108
grip strength	forelimb grip strength (mean of trials), average	0.97454	7.2680	0.41063	0.961	0.894
grip strength	forelimb grip strength (mean of trials), average normalized to bw	-7.9078	13.074	-2.4597	0.773	0.550
grip strength	forelimb grip strength by trial, trial1	7.3614	7.4099	1.1084	0.670	0.328
grip strength	forelimb grip strength by trial, trial2	-0.34429	5.9220	0.17369	0.983	0.954
grip strength	forelimb grip strength by trial, trial3	2.8005	7.8496	0.55430	0.888	0.724
heart weight	heart weight, normalized to body weight	0.32319	0.16843	0.65720	0.210	0.0675
heart weight	heart weight, weight	5.2372	5.0033	0.30534	0.518	0.306
hematology	basophil differential (percent of total WBC)	0.054523	0.055202	0.82068	0.741	0.336
hematology	calculated hemoglobin (cHGB)	-0.84822	0.95745	-2.0238	0.657	0.387
hematology	eosinophil differential (percent of total WBC)	-0.34803	0.16095	-0.85455	0.327	0.0436
hematology	hematocrit (HCT)	-3.0668	3.2431	-2.2236	0.628	0.356
hematology	hemoglobin concentration distribution width (HDW)	-0.015639	0.028280	-0.41678	0.796	0.587
hematology	large unstained cells (percent of total WBC)	0.078938	0.090385	0.51228	0.713	0.394
hematology	lymphocyte differential (percent of total WBC)	-1.1251	0.78948	-0.52158	0.423	0.170
hematology	mean corpuscular hemoglobin (CHr)	0.15141	0.067968	1.1282	0.150	0.0382
hematology	mean platelet volume (MPV)	-0.16852	0.096216	-1.0997	0.258	0.0960
hematology	mean RBC corpuscular hemoglobin (MCH)	0.62495	0.64526	1.6863	0.701	0.345
hematology	mean RBC corpuscular hemoglobin concentration (MCHC)	0.56957	1.3282	1.0857	0.877	0.673
hematology	mean RBC corpuscular volume (MCV)	0.65631	0.35521	1.1121	0.226	0.0803
hematology	measured hemoglobin (mHGB)	-0.84090	0.96938	-1.5593	0.675	0.397
hematology	monocyte differential (percent of total WBC)	0.013941	0.10565	0.25137	0.960	0.896
hematology	neutrophil differential (percent of total WBC)	1.4099	0.65290	0.73673	0.196	0.0438
hematology	platelet count (PLT; units per volume x 10³)	-121.74	97.069	-1.3968	0.592	0.225
hematology	RBC corpuscular distribution width (RDW)	0.072684	0.12264	0.25703	0.763	0.560
hematology	RBC corpuscular hemoglobin concentration mean (CHCM)	-0.22479	0.24333	-0.63779	0.630	0.367
hematology	red blood cell count (RBC; per volume x 10⁶)	-0.73064	0.70613	-2.2568	0.579	0.314
hematology	reticulocyte count (Retic; units per volume x 10⁹)	-21.943	25.619	-0.86335	0.755	0.402
hematology	reticulocyte differential (percent of total RBC)	-0.12876	0.092696	-0.35368	0.540	0.181
hematology	white blood cell count (WBC; units per volume x 10³)	-0.41839	0.59968	-0.11781	0.678	0.494
holeboard	number of hole pokes by individual hole number, 20 min test, 1	1.5693	0.94369	1.3863	0.588	0.103
holeboard	number of hole pokes by individual hole number, 20 min test, 2	1.0929	0.45372	1.7085	0.368	0.0197
holeboard	number of hole pokes by individual hole number, 20 min test, 3	0.95148	0.45805	1.4366	0.576	0.0429
holeboard	number of hole pokes by individual hole number, 20 min test, 4	2.6865	0.77008	2.0780	0.110	0.00101
holeboard	number of hole pokes by individual hole number, 20 min test, 5	1.6496	0.67328	2.2533	0.383	0.0178
holeboard	number of hole pokes by individual hole number, 20 min test, 6	0.097679	0.26623	0.30668	0.957	0.715
holeboard	number of hole pokes by individual hole number, 20 min test, 7	0.24099	0.48651	0.63212	0.958	0.622
holeboard	number of hole pokes by individual hole number, 20 min test, 8	0.40084	0.49281	0.81781	0.844	0.420
holeboard	number of hole pokes by individual hole number, 20 min test, 9	1.2814	0.48537	1.8860	0.267	0.0110
holeboard	number of hole pokes by individual hole number, 20 min test, 10	0.32351	0.43113	0.87934	0.879	0.456
holeboard	number of hole pokes by individual hole number, 20 min test, 11	0.67440	0.37444	1.4554	0.661	0.0776
holeboard	number of hole pokes by individual hole number, 20 min test, 12	2.7295	0.63142	3.0009	0.0272	0.0000733
holeboard	number of hole pokes by individual hole number, 20 min test, 13	4.6415	1.1732	2.7831	0.0510	0.000241
holeboard	number of hole pokes by individual hole number, 20 min test, 14	2.0453	0.72905	2.5502	0.261	0.00714
holeboard	number of hole pokes by individual hole number, 20 min test, 15	0.36874	0.54879	0.64825	0.852	0.505
holeboard	number of hole pokes by individual hole number, 20 min test, 16	4.3383	1.1783	2.8752	0.0756	0.000560
holeboard	total number of hole pokes, 20 min test	29.644	6.1939	2.8752	0.00341	0.0000155
light / dark	fecal boli count, 20 min test	0.38836	0.69450	0.48022	0.857	0.579
light / dark	latency to enter dark zone, 20 min test	-102.63	33.255	-1.9632	0.129	0.00313
light / dark	number of transitions between light and dark zones, 20 min test	-9.4706	6.3465	-0.85480	0.438	0.141
light / dark	percentage of total time in dark zone, 20 min test	12.764	3.0555	2.2792	0.0117	0.000102
light / dark	percentage of total time in light zone, 20 min test	-12.764	3.0555	-2.2792	0.0117	0.000102
light / dark	time mobile in dark zone, 20 min test	97.125	13.377	2.5495	2.71e-7	1.17e-9
light / dark	time mobile in light zone, 20 min test	-27.027	9.7793	-1.9821	0.0672	0.00768
light / dark	time spent in dark zone, 20 min test	222.51	41.604	2.8542	0.00151	0.00000163
light / dark	time spent in light zone, 20 min test	-222.51	41.604	-2.8542	0.00151	0.00000163
open field	average speed in center of arena, 20 min test	1.5725	0.50401	2.1427	0.0612	0.00275
open field	average speed in periphery of arena, 20 min test	0.63984	0.19761	1.6064	0.0185	0.00194
open field	distance traveled habituation ratio, 20 min test	3.3506	10.228	0.31599	0.893	0.744
open field	distance traveled in center of arena, 20 min test	-360.09	124.95	-2.1845	0.0496	0.00545
open field	distance traveled in periphery of arena, 20 min test	949.47	206.01	2.1168	0.000634	0.0000207
open field	distance traveled slope, 20 min test	2.2370	9.5811	0.27950	0.940	0.816
open field	distance traveled, 20 min test, 1st 5min	127.64	130.20	0.64239	0.572	0.331
open field	distance traveled, 20 min test, 2nd 5min	202.33	73.940	1.5114	0.0583	0.00809
open field	distance traveled, 20 min test, 3rd 5min	178.94	66.900	1.3956	0.0642	0.00955
open field	distance traveled, 20 min test, 4th 5min	186.47	62.574	1.3885	0.0376	0.00411
open field	number of clockwise revolution episodes, 20 min test	1.9503	1.2537	0.73388	0.455	0.125
open field	number of counter-clockwise revolution episodes, 20 min test	0.58660	1.3312	-0.12722	0.830	0.661
open field	number of fecal boli, 20 min test	2.2565	0.87310	1.8548	0.164	0.0121
open field	number of rears in 5 min bins, 20 min test, 1st 5min	-6.4315	1.6945	-1.8806	0.0120	0.000337
open field	number of rears in 5 min bins, 20 min test, 2nd 5min	-2.7167	2.6104	-1.0229	0.588	0.302
open field	number of rears in 5 min bins, 20 min test, 3rd 5min	-4.2445	3.7735	-1.2715	0.544	0.265
open field	number of rears in 5 min bins, 20 min test, 4th 5min	-4.9350	3.5778	-1.3992	0.442	0.173
open field	percentage of total time in center of arena, 20 min test	-8.9846	2.5718	-2.3198	0.0305	0.000886
open field	percentage of total time in center of arena, slope, 20 min test	-4.4441	1.1847	-2.0575	0.0601	0.000389
open field	percentage of total time in center, habituation ratio, 20 min test	-4.3711	1.1276	-1.8809	0.0549	0.000258
open field	percentage of total time in corners of arena, 20 min test	30.695	5.3532	3.2711	0.000152	3.26e-7
open field	percentage of total time in corners, habituation ratio, 20 min test	7.6442	2.2103	2.6288	0.0889	0.000996
open field	percentage of total time in corners, slope, 20 min test	7.5662	2.2226	2.6288	0.0951	0.00118
open field	permanence time in center of arena, 20 min test	-107.82	30.862	-2.3198	0.0311	0.000885
open field	permanence time in corners of arena, 20 min test	368.32	64.238	3.2711	0.000152	3.26e-7
open field	permanence time in periphery of arena, 20 min test	107.83	30.866	2.3198	0.0311	0.000886
open field	total distance traveled, 20 min test	724.01	253.15	1.3850	0.0376	0.00577
open field	total number of rears, 20 min test	-22.357	11.233	-1.7871	0.207	0.0510
open field	whole arena average speed, 20 min test	0.60361	0.21083	1.3850	0.0373	0.00572
open field	whole arena resting time, 20 min test	-47.531	22.423	-0.75198	0.134	0.0380
open field	whole arena time spent mobile, 20 min test	47.384	22.426	0.99384	0.137	0.0386
open field	whole arena time spent vertical, 20 min test	-15.367	13.200	-1.2715	0.548	0.249
SHIRPA	locomotor activity (number of squares in the arena the mouse moves into with all four paws in first 30 s of test)	1.1375	1.8870	0.66757	0.793	0.551
startle / PPI	average baseline movement during background noise	-0.27911	1.7961	-0.13138	0.989	0.877
startle / PPI	average of each corrected maximum percent pre-pulse inhibition value	-0.089127	0.064381	-0.91116	0.526	0.172
startle / PPI	average of each corrected percent pre-pulse inhibition value	-0.077772	0.063092	-0.86667	0.576	0.223
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-9.8939	7.1955	-1.0230	0.846	0.175
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-10.882	7.4507	-1.1122	0.508	0.150
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-3.0426	5.9302	-0.41744	0.845	0.610
startle / PPI	average startle response to full pulse (120 dB)	-93.909	55.234	-1.3271	0.271	0.0946
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-16.210	44.555	-0.15829	0.861	0.717
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-64.346	53.259	-1.0066	0.453	0.232
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-78.595	46.165	-1.4363	0.274	0.0942
startle / PPI	average startle response to pre-pulse, 74dB sound pressure level	0.83749	1.8482	0.61794	0.934	0.652
startle / PPI	average startle response to pre-pulse, 78dB sound pressure level	-1.2671	1.3744	-0.88184	0.844	0.360
startle / PPI	average startle response to pre-pulse, 82dB sound pressure level	3.7941	2.3582	1.2781	0.538	0.113
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-0.098732	0.077489	-0.87771	0.850	0.208
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-0.11301	0.080214	-1.0223	0.506	0.164
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-0.020460	0.068971	-0.35948	0.899	0.768
startle / PPI	corrected average startle response to full pulse (120 dB) minus average baseline movement during background noise	-94.710	55.121	-1.3271	0.260	0.0913
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 74dB sound pressure level	-14.640	45.024	-0.13280	0.877	0.746
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 78dB sound pressure level	-63.366	53.593	-0.99731	0.459	0.242
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 82dB sound pressure level	-82.389	46.555	-1.4936	0.243	0.0822
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-0.11611	0.077612	-0.98586	0.804	0.140
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-0.13036	0.084238	-1.0963	0.449	0.127
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-0.023463	0.070447	-0.37297	0.888	0.740
startle / PPI	corrected maximum startle response to full pulse (120 dB) minus maximum baseline movement during background noise	-374.31	207.10	-1.4603	0.237	0.0761
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 74dB sound pressure level	-39.860	169.00	-0.058180	0.916	0.814
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 78dB sound pressure level	-247.70	200.89	-1.0715	0.438	0.223
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 82dB sound pressure level	-291.27	169.64	-1.4324	0.254	0.0915
startle / PPI	maximum baseline movement during background noise	-0.18476	4.2546	0.082058	0.991	0.966
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-11.510	7.4538	-1.0890	0.809	0.128
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-12.753	8.0324	-1.1713	0.455	0.118
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-3.1731	6.4166	-0.42510	0.827	0.623
startle / PPI	maximum startle response to full pulse (120 dB)	-372.49	207.43	-1.4522	0.240	0.0779
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-43.491	168.35	-0.082058	0.904	0.797
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-247.28	200.36	-1.0591	0.440	0.222
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-281.94	168.95	-1.4018	0.276	0.101
startle / PPI	maximum startle response to pre-pulse, 74dB sound pressure level	2.4849	4.2263	0.77707	0.880	0.559
startle / PPI	maximum startle response to pre-pulse, 78dB sound pressure level	-2.0110	3.3309	-0.54330	0.882	0.548
startle / PPI	maximum startle response to pre-pulse, 82dB sound pressure level	9.3304	5.7699	1.2289	0.493	0.111

MULTIPLE (CATEGORICAL) TRAIT PROFILE PLOT — Early Adult Phenotyping study (EAP)

Procedure	JaxKOMP-EAP Trait	Sex	Trait Effect	P-value
eye morphology	anterior chamber depth	females	1.0 %	1.0
eye morphology	anterior chamber depth	males	0.0 %	1.0
eye morphology	anterior chamber depth	both	1.0 %	1.0
eye morphology	bulging eye	females	1.0 %	1.0
eye morphology	bulging eye	males	0.0 %	1.0
eye morphology	bulging eye	both	1.0 %	1.00
eye morphology	cornea	females	4.0 %	1.0
eye morphology	cornea	males	27.0 %	0.00504
eye morphology	cornea	both	12.0 %	0.0577
eye morphology	cornea opacity	females	5.0 %	1.0
eye morphology	cornea opacity	males	14.0 %	0.0979
eye morphology	cornea opacity	both	5.0 %	0.387
eye morphology	cornea vascularization	females	3.0 %	1.0
eye morphology	cornea vascularization	males	1.0 %	1.0
eye morphology	cornea vascularization	both	2.0 %	1.0
eye morphology	corneal deposits	females	2.0 %	1.0
eye morphology	corneal deposits	males	1.0 %	1.0
eye morphology	corneal deposits	both	1.0 %	1.00
eye morphology	corneal mineralization	females	2.0 %	1.0
eye morphology	corneal mineralization	males	1.0 %	1.0
eye morphology	corneal mineralization	both	1.0 %	1.00
eye morphology	corneal scleralization	females	3.0 %	1.0
eye morphology	corneal scleralization	males	1.0 %	1.0
eye morphology	corneal scleralization	both	2.0 %	1.0
eye morphology	corneal ulcer	females	1.0 %	1.0
eye morphology	corneal ulcer	males	1.0 %	1.0
eye morphology	corneal ulcer	both	1.0 %	1.00
eye morphology	eye closure	females	1.0 %	1.0
eye morphology	eye closure	males	0.0 %	1.0
eye morphology	eye closure	both	1.0 %	1.00
eye morphology	eye hemorrhage or blood presence	females	2.0 %	1.0
eye morphology	eye hemorrhage or blood presence	males	1.0 %	1.0
eye morphology	eye hemorrhage or blood presence	both	1.0 %	1.0
eye morphology	eyelid morphology	females	1.0 %	1.0
eye morphology	eyelid morphology	males	0.0 %	1.0
eye morphology	eyelid morphology	both	1.0 %	1.00
eye morphology	eyes (present, absent)	females	1.0 %	1.0
eye morphology	eyes (present, absent)	males	0.0 %	1.0
eye morphology	eyes (present, absent)	both	0.0 %	1.00
eye morphology	fusion between cornea and lens	females	4.0 %	1.0
eye morphology	fusion between cornea and lens	males	2.0 %	1.0
eye morphology	fusion between cornea and lens	both	3.0 %	1.0
eye morphology	iris pigmentation	females	2.0 %	1.0
eye morphology	iris pigmentation	males	1.0 %	1.0
eye morphology	iris pigmentation	both	2.0 %	1.0
eye morphology	iris transillumination	females	2.0 %	1.0
eye morphology	iris transillumination	males	1.0 %	1.00
eye morphology	iris transillumination	both	1.0 %	1.00
eye morphology	irispupil	females	4.0 %	1.0
eye morphology	irispupil	males	3.0 %	1.0
eye morphology	irispupil	both	3.0 %	1.0
eye morphology	lacrimation	females	3.0 %	1.00
eye morphology	lacrimation	males	2.0 %	1.0
eye morphology	lacrimation	both	3.0 %	1.00
eye morphology	lens	females	10.0 %	1.0
eye morphology	lens	males	8.0 %	1.00
eye morphology	lens	both	9.0 %	1.00
eye morphology	lens opacity	females	11.0 %	0.484
eye morphology	lens opacity	males	6.0 %	1.00
eye morphology	lens opacity	both	4.0 %	0.654
eye morphology	narrow eye opening	females	2.0 %	1.00
eye morphology	narrow eye opening	males	1.0 %	1.0
eye morphology	narrow eye opening	both	1.0 %	1.00
eye morphology	optic disc	females	4.0 %	1.0
eye morphology	optic disc	males	2.0 %	1.00
eye morphology	optic disc	both	3.0 %	1.00
eye morphology	persistence of hyaloid vascular system	females	14.0 %	0.181
eye morphology	persistence of hyaloid vascular system	males	5.0 %	1.0
eye morphology	persistence of hyaloid vascular system	both	7.0 %	0.279
eye morphology	pupil dilation	females	2.0 %	1.0
eye morphology	pupil dilation	males	1.0 %	1.00
eye morphology	pupil dilation	both	2.0 %	1.00
eye morphology	pupil light response	females	2.0 %	1.0
eye morphology	pupil light response	males	1.0 %	1.0
eye morphology	pupil light response	both	2.0 %	1.0
eye morphology	pupil position	females	4.0 %	1.0
eye morphology	pupil position	males	3.0 %	1.0
eye morphology	pupil position	both	4.0 %	1.0
eye morphology	pupil shape	females	3.0 %	1.0
eye morphology	pupil shape	males	2.0 %	1.0
eye morphology	pupil shape	both	3.0 %	1.0
eye morphology	retina	females	10.0 %	1.0
eye morphology	retina	males	16.0 %	1.0
eye morphology	retina	both	13.0 %	1.00
eye morphology	retinal blood vessels	females	4.0 %	1.0
eye morphology	retinal blood vessels	males	2.0 %	1.0
eye morphology	retinal blood vessels	both	3.0 %	1.00
eye morphology	retinal blood vessels pattern	females	5.0 %	1.0
eye morphology	retinal blood vessels pattern	males	2.0 %	1.00
eye morphology	retinal blood vessels pattern	both	4.0 %	1.00
eye morphology	retinal blood vessels structure	females	4.0 %	1.0
eye morphology	retinal blood vessels structure	males	2.0 %	1.0
eye morphology	retinal blood vessels structure	both	3.0 %	1.0
eye morphology	retinal pigmentation	females	12.0 %	1.0
eye morphology	retinal pigmentation	males	11.0 %	0.380
eye morphology	retinal pigmentation	both	6.0 %	0.680
eye morphology	retinal structure	females	4.0 %	1.0
eye morphology	retinal structure	males	2.0 %	1.00
eye morphology	retinal structure	both	3.0 %	1.00
eye morphology	synechia	females	4.0 %	1.0
eye morphology	synechia	males	2.0 %	1.00
eye morphology	synechia	both	3.0 %	1.00
eye morphology	vitreous	females	4.0 %	1.0
eye morphology	vitreous	males	2.0 %	1.0
eye morphology	vitreous	both	3.0 %	1.0
SHIRPA	activity body position	females	1.0 %	1.0
SHIRPA	activity body position	males	2.0 %	1.0
SHIRPA	activity body position	both	1.0 %	1.00
SHIRPA	aggression	females	0.0 %	1.00
SHIRPA	aggression	males	1.0 %	1.0
SHIRPA	aggression	both	1.0 %	1.00
SHIRPA	body length	females	0.0 %	1.00
SHIRPA	body length	males	0.0 %	1.0
SHIRPA	body length	both	0.0 %	1.00
SHIRPA	body position	females	0.0 %	1.00
SHIRPA	body position	males	1.0 %	1.0
SHIRPA	body position	both	0.0 %	1.0
SHIRPA	body thickness	females	1.0 %	1.00
SHIRPA	body thickness	males	0.0 %	1.0
SHIRPA	body thickness	both	0.0 %	1.0
SHIRPA	coat color abdomen	females	3.0 %	1.00
SHIRPA	coat color abdomen	males	4.0 %	1.0
SHIRPA	coat color abdomen	both	4.0 %	1.00
SHIRPA	coat color back	females	0.0 %	1.00
SHIRPA	coat color back	males	0.0 %	1.00
SHIRPA	coat color back	both	0.0 %	1.00
SHIRPA	coat color head	females	0.0 %	1.00
SHIRPA	coat color head	males	0.0 %	1.00
SHIRPA	coat color head	both	0.0 %	1.0
SHIRPA	coat color pattern abdomen	females	1.0 %	1.00
SHIRPA	coat color pattern abdomen	males	1.0 %	1.0
SHIRPA	coat color pattern abdomen	both	1.0 %	1.00
SHIRPA	coat color pattern back	females	0.0 %	1.00
SHIRPA	coat color pattern back	males	0.0 %	1.00
SHIRPA	coat color pattern back	both	0.0 %	1.0
SHIRPA	coat color pattern head	females	0.0 %	1.00
SHIRPA	coat color pattern head	males	0.0 %	1.0
SHIRPA	coat color pattern head	both	0.0 %	1.00
SHIRPA	coat hair abdomen texture appearance	females	2.0 %	1.0
SHIRPA	coat hair abdomen texture appearance	males	2.0 %	1.0
SHIRPA	coat hair abdomen texture appearance	both	2.0 %	1.0
SHIRPA	coat hair back texture appearance	females	0.0 %	1.00
SHIRPA	coat hair back texture appearance	males	0.0 %	1.0
SHIRPA	coat hair back texture appearance	both	0.0 %	1.0
SHIRPA	coat hair distribution abdomen	females	0.0 %	1.00
SHIRPA	coat hair distribution abdomen	males	1.0 %	1.0
SHIRPA	coat hair distribution abdomen	both	1.0 %	1.0
SHIRPA	coat hair distribution back	females	0.0 %	1.00
SHIRPA	coat hair distribution back	males	0.0 %	1.0
SHIRPA	coat hair distribution back	both	0.0 %	1.00
SHIRPA	coat hair distribution head	females	1.0 %	1.00
SHIRPA	coat hair distribution head	males	1.0 %	1.0
SHIRPA	coat hair distribution head	both	1.0 %	1.0
SHIRPA	coat hair head texture appearance	females	0.0 %	1.00
SHIRPA	coat hair head texture appearance	males	0.0 %	1.0
SHIRPA	coat hair head texture appearance	both	0.0 %	1.0
SHIRPA	contact righting	females	5.0 %	1.0
SHIRPA	contact righting	males	5.0 %	1.0
SHIRPA	contact righting	both	5.0 %	1.0
SHIRPA	ear morphology	females	0.0 %	1.0
SHIRPA	ear morphology	males	0.0 %	1.0
SHIRPA	ear morphology	both	0.0 %	1.0
SHIRPA	fat distribution	females	0.0 %	1.00
SHIRPA	fat distribution	males	0.0 %	1.0
SHIRPA	fat distribution	both	0.0 %	1.0
SHIRPA	forelimb digit number	females	0.0 %	1.00
SHIRPA	forelimb digit number	males	0.0 %	1.0
SHIRPA	forelimb digit number	both	0.0 %	1.0
SHIRPA	forelimb digit position	females	0.0 %	1.0
SHIRPA	forelimb digit position	males	0.0 %	1.0
SHIRPA	forelimb digit position	both	0.0 %	1.0
SHIRPA	forelimb digit shape	females	0.0 %	1.0
SHIRPA	forelimb digit shape	males	0.0 %	1.0
SHIRPA	forelimb digit shape	both	0.0 %	1.0
SHIRPA	forelimb digit size	females	0.0 %	1.0
SHIRPA	forelimb digit size	males	0.0 %	1.0
SHIRPA	forelimb digit size	both	0.0 %	1.0
SHIRPA	forelimb footpads	females	0.0 %	1.00
SHIRPA	forelimb footpads	males	0.0 %	1.0
SHIRPA	forelimb footpads	both	0.0 %	1.0
SHIRPA	forelimb nail length	females	0.0 %	1.0
SHIRPA	forelimb nail length	males	0.0 %	1.0
SHIRPA	forelimb nail length	both	0.0 %	1.0
SHIRPA	forelimb nail number	females	0.0 %	1.0
SHIRPA	forelimb nail number	males	0.0 %	1.0
SHIRPA	forelimb nail number	both	0.0 %	1.0
SHIRPA	forelimb nail position	females	0.0 %	1.0
SHIRPA	forelimb nail position	males	0.0 %	1.0
SHIRPA	forelimb nail position	both	0.0 %	1.0
SHIRPA	forelimb nail shape	females	0.0 %	1.0
SHIRPA	forelimb nail shape	males	0.0 %	1.0
SHIRPA	forelimb nail shape	both	0.0 %	1.0
SHIRPA	forelimbs position	females	0.0 %	1.0
SHIRPA	forelimbs position	males	0.0 %	1.0
SHIRPA	forelimbs position	both	0.0 %	1.0
SHIRPA	forelimbs shape	females	0.0 %	1.0
SHIRPA	forelimbs shape	males	0.0 %	1.0
SHIRPA	forelimbs shape	both	0.0 %	1.0
SHIRPA	forelimbs size	females	0.0 %	1.00
SHIRPA	forelimbs size	males	0.0 %	1.0
SHIRPA	forelimbs size	both	0.0 %	1.0
SHIRPA	forepaw position	females	0.0 %	1.0
SHIRPA	forepaw position	males	0.0 %	1.0
SHIRPA	forepaw position	both	0.0 %	1.0
SHIRPA	forepaw shape	females	0.0 %	1.0
SHIRPA	forepaw shape	males	0.0 %	1.0
SHIRPA	forepaw shape	both	0.0 %	1.0
SHIRPA	forepaw size	females	0.0 %	1.0
SHIRPA	forepaw size	males	0.0 %	1.0
SHIRPA	forepaw size	both	0.0 %	1.0
SHIRPA	gait (fluidity)	females	0.0 %	1.0
SHIRPA	gait (fluidity)	males	0.0 %	1.0
SHIRPA	gait (fluidity)	both	0.0 %	1.0
SHIRPA	genitalia morphology	females	0.0 %	1.00
SHIRPA	genitalia morphology	males	0.0 %	1.0
SHIRPA	genitalia morphology	both	0.0 %	1.0
SHIRPA	genitalia presence	females	0.0 %	1.00
SHIRPA	genitalia presence	males	0.0 %	1.0
SHIRPA	genitalia presence	both	0.0 %	1.0
SHIRPA	genitalia size	females	0.0 %	1.0
SHIRPA	genitalia size	males	0.0 %	1.0
SHIRPA	genitalia size	both	0.0 %	1.0
SHIRPA	head bobbing	females	0.0 %	1.0
SHIRPA	head bobbing	males	0.0 %	1.0
SHIRPA	head bobbing	both	0.0 %	1.0
SHIRPA	head morphology	females	0.0 %	1.00
SHIRPA	head morphology	males	16.0 %	0.0199
SHIRPA	head morphology	both	10.0 %	0.0201
SHIRPA	head size	females	0.0 %	1.0
SHIRPA	head size	males	0.0 %	1.0
SHIRPA	head size	both	0.0 %	1.0
SHIRPA	hindlimb digit number	females	25.0 %	0.00451
SHIRPA	hindlimb digit number	males	0.0 %	1.0
SHIRPA	hindlimb digit number	both	10.0 %	0.00599
SHIRPA	hindlimb digit position	females	0.0 %	1.00
SHIRPA	hindlimb digit position	males	0.0 %	1.0
SHIRPA	hindlimb digit position	both	0.0 %	1.0
SHIRPA	hindlimb digit shape	females	0.0 %	1.00
SHIRPA	hindlimb digit shape	males	0.0 %	1.0
SHIRPA	hindlimb digit shape	both	0.0 %	1.00
SHIRPA	hindlimb digit size	females	0.0 %	1.00
SHIRPA	hindlimb digit size	males	0.0 %	1.0
SHIRPA	hindlimb digit size	both	0.0 %	1.0
SHIRPA	hindlimb nail length	females	0.0 %	1.0
SHIRPA	hindlimb nail length	males	0.0 %	1.0
SHIRPA	hindlimb nail length	both	0.0 %	1.0
SHIRPA	hindlimb nail number	females	0.0 %	1.0
SHIRPA	hindlimb nail number	males	1.0 %	1.0
SHIRPA	hindlimb nail number	both	0.0 %	1.0
SHIRPA	hindlimb nail position	females	0.0 %	1.0
SHIRPA	hindlimb nail position	males	0.0 %	1.0
SHIRPA	hindlimb nail position	both	0.0 %	1.0
SHIRPA	hindlimb nail shape	females	0.0 %	1.0
SHIRPA	hindlimb nail shape	males	0.0 %	1.0
SHIRPA	hindlimb nail shape	both	0.0 %	1.0
SHIRPA	hindlimbs footpads	females	0.0 %	1.00
SHIRPA	hindlimbs footpads	males	0.0 %	1.0
SHIRPA	hindlimbs footpads	both	0.0 %	1.0
SHIRPA	hindlimbs position	females	0.0 %	1.0
SHIRPA	hindlimbs position	males	0.0 %	1.0
SHIRPA	hindlimbs position	both	0.0 %	1.0
SHIRPA	hindlimbs shape	females	0.0 %	1.0
SHIRPA	hindlimbs shape	males	0.0 %	1.0
SHIRPA	hindlimbs shape	both	0.0 %	1.0
SHIRPA	hindlimbs size	females	0.0 %	1.0
SHIRPA	hindlimbs size	males	0.0 %	1.0
SHIRPA	hindlimbs size	both	0.0 %	1.0
SHIRPA	hindpaw position	females	0.0 %	1.0
SHIRPA	hindpaw position	males	0.0 %	1.0
SHIRPA	hindpaw position	both	0.0 %	1.0
SHIRPA	hindpaw shape	females	0.0 %	1.00
SHIRPA	hindpaw shape	males	0.0 %	1.0
SHIRPA	hindpaw shape	both	0.0 %	1.0
SHIRPA	hindpaw size	females	0.0 %	1.00
SHIRPA	hindpaw size	males	0.0 %	1.0
SHIRPA	hindpaw size	both	0.0 %	1.0
SHIRPA	limb grasp	females	9.0 %	1.00
SHIRPA	limb grasp	males	11.0 %	0.297
SHIRPA	limb grasp	both	3.0 %	0.530
SHIRPA	lower lip morphology	females	0.0 %	1.00
SHIRPA	lower lip morphology	males	0.0 %	1.0
SHIRPA	lower lip morphology	both	0.0 %	1.0
SHIRPA	lower teeth appearance	females	0.0 %	1.0
SHIRPA	lower teeth appearance	males	0.0 %	1.00
SHIRPA	lower teeth appearance	both	0.0 %	1.0
SHIRPA	mouth morphology	females	0.0 %	1.0
SHIRPA	mouth morphology	males	0.0 %	1.0
SHIRPA	mouth morphology	both	0.0 %	1.0
SHIRPA	salivation	females	0.0 %	1.0
SHIRPA	salivation	males	0.0 %	1.0
SHIRPA	salivation	both	0.0 %	1.0
SHIRPA	skin color back paws	females	0.0 %	1.0
SHIRPA	skin color back paws	males	0.0 %	1.0
SHIRPA	skin color back paws	both	0.0 %	1.0
SHIRPA	skin color ear	females	0.0 %	1.0
SHIRPA	skin color ear	males	0.0 %	1.0
SHIRPA	skin color ear	both	0.0 %	1.0
SHIRPA	skin color front paws	females	0.0 %	1.0
SHIRPA	skin color front paws	males	0.0 %	1.0
SHIRPA	skin color front paws	both	0.0 %	1.0
SHIRPA	skin color snout	females	0.0 %	1.0
SHIRPA	skin color snout	males	0.0 %	1.0
SHIRPA	skin color snout	both	0.0 %	1.0
SHIRPA	skin color tail	females	0.0 %	1.0
SHIRPA	skin color tail	males	0.0 %	1.0
SHIRPA	skin color tail	both	0.0 %	1.0
SHIRPA	skin color whole body	females	0.0 %	1.00
SHIRPA	skin color whole body	males	0.0 %	1.0
SHIRPA	skin color whole body	both	0.0 %	1.0
SHIRPA	skin texture back paw	females	0.0 %	1.0
SHIRPA	skin texture back paw	males	0.0 %	1.0
SHIRPA	skin texture back paw	both	0.0 %	1.0
SHIRPA	skin texture ear	females	0.0 %	1.0
SHIRPA	skin texture ear	males	0.0 %	1.0
SHIRPA	skin texture ear	both	0.0 %	1.0
SHIRPA	skin texture front paws	females	0.0 %	1.0
SHIRPA	skin texture front paws	males	0.0 %	1.0
SHIRPA	skin texture front paws	both	0.0 %	1.0
SHIRPA	skin texture snout	females	0.0 %	1.0
SHIRPA	skin texture snout	males	0.0 %	1.0
SHIRPA	skin texture snout	both	0.0 %	1.0
SHIRPA	skin texture tail	females	0.0 %	1.0
SHIRPA	skin texture tail	males	0.0 %	1.0
SHIRPA	skin texture tail	both	0.0 %	1.0
SHIRPA	skin texture whole body	females	0.0 %	1.0
SHIRPA	skin texture whole body	males	0.0 %	1.0
SHIRPA	skin texture whole body	both	0.0 %	1.00
SHIRPA	snout size	females	0.0 %	1.00
SHIRPA	snout size	males	1.0 %	1.00
SHIRPA	snout size	both	0.0 %	1.00
SHIRPA	startle response	females	0.0 %	1.0
SHIRPA	startle response	males	0.0 %	1.00
SHIRPA	startle response	both	0.0 %	1.00
SHIRPA	tail curvature	females	0.0 %	1.0
SHIRPA	tail curvature	males	0.0 %	1.0
SHIRPA	tail curvature	both	0.0 %	1.0
SHIRPA	tail elevation	females	1.0 %	1.00
SHIRPA	tail elevation	males	2.0 %	1.0
SHIRPA	tail elevation	both	1.0 %	1.0
SHIRPA	tail length	females	0.0 %	1.00
SHIRPA	tail length	males	0.0 %	1.0
SHIRPA	tail length	both	0.0 %	1.0
SHIRPA	tail morphology	females	0.0 %	1.00
SHIRPA	tail morphology	males	0.0 %	1.0
SHIRPA	tail morphology	both	0.0 %	1.00
SHIRPA	tail presence	females	0.0 %	1.0
SHIRPA	tail presence	males	0.0 %	1.0
SHIRPA	tail presence	both	0.0 %	1.0
SHIRPA	tail shape	females	0.0 %	1.00
SHIRPA	tail shape	males	0.0 %	1.0
SHIRPA	tail shape	both	0.0 %	1.0
SHIRPA	tail thickness	females	0.0 %	1.0
SHIRPA	tail thickness	males	0.0 %	1.0
SHIRPA	tail thickness	both	0.0 %	1.0
SHIRPA	teeth presence	females	0.0 %	1.00
SHIRPA	teeth presence	males	0.0 %	1.0
SHIRPA	teeth presence	both	0.0 %	1.0
SHIRPA	transfer arousal	females	1.0 %	1.0
SHIRPA	transfer arousal	males	2.0 %	1.0
SHIRPA	transfer arousal	both	1.0 %	1.0
SHIRPA	tremor	females	0.0 %	1.00
SHIRPA	tremor	males	0.0 %	1.00
SHIRPA	tremor	both	0.0 %	1.00
SHIRPA	trunk curl	females	0.0 %	1.00
SHIRPA	trunk curl	males	0.0 %	1.0
SHIRPA	trunk curl	both	0.0 %	1.0
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	females	0.0 %	1.0
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	males	0.0 %	1.0
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	both	0.0 %	1.0
SHIRPA	upper lip morphology	females	0.0 %	1.0
SHIRPA	upper lip morphology	males	0.0 %	1.0
SHIRPA	upper lip morphology	both	0.0 %	1.0
SHIRPA	upper teeth appearance	females	0.0 %	1.00
SHIRPA	upper teeth appearance	males	0.0 %	1.0
SHIRPA	upper teeth appearance	both	0.0 %	1.0
SHIRPA	vibrissae appearance	females	2.0 %	1.0
SHIRPA	vibrissae appearance	males	1.0 %	1.0
SHIRPA	vibrissae appearance	both	1.0 %	1.0
SHIRPA	vibrissae presence	females	2.0 %	1.0
SHIRPA	vibrissae presence	males	1.0 %	1.0
SHIRPA	vibrissae presence	both	2.0 %	1.0
SHIRPA	vocalization	females	2.0 %	1.00
SHIRPA	vocalization	males	2.0 %	1.0
SHIRPA	vocalization	both	2.0 %	1.0

GENOTYPE CORRELATION PLOT

Correlate Stxbp1^{tm1b(EUCOMM)Hmgu} -/+ with genotype: