MPD: JaxKOMP-EAP genotype: Epb41l1<sup>tm1b(EUCOMM)Wtsi</sup> -/-

JaxKOMP-EAP effect sizes: Epb41l1^{tm1b(EUCOMM)Wtsi} -/- Gene Epb41l1

MULTIPLE (NUMERIC) TRAIT PROFILE PLOT — Early Adult Phenotyping study (EAP)

Procedure	JaxKOMP-EAP Trait	Trait Effect	Trait Effect SE	Trait Effect RankZ	Adjusted p-value	Unadjusted p-value
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 6 kHz pip	4.8729	1.9669	1.0741	0.285	0.0277
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 12 kHz pip	4.7585	3.1881	0.98530	0.654	0.161
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 18 kHz pip	2.7826	2.0753	0.41107	0.558	0.203
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 24 kHz pip	-4.5512	3.1596	-0.84002	0.556	0.173
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 30 kHz pip	-15.632	3.1641	-1.8017	0.0208	0.000270
body composition	body length	-0.12166	0.042510	-1.0742	0.0665	0.00681
body composition	body weight (at time of DXA)	-3.2599	0.60216	-1.7666	0.000113	0.00000337
body composition	bone area, whole body scan, head excluded	0.31723	0.19067	1.5113	0.330	0.104
body composition	bone mineral content of whole body scan, head excluded	0.013931	0.014156	0.95442	0.621	0.331
body composition	bone mineral content to body weight ratio	0.00060993	0.00058029	0.98059	0.577	0.300
body composition	bone mineral density of whole body scan, head excluded	-0.00010579	0.00071630	-0.084109	0.960	0.883
body composition	fat tissue mass of whole body scan, head excluded	-0.65314	0.36715	-1.2206	0.272	0.0832
body composition	fat tissue mass to body weight ratio	-0.024767	0.012802	-1.1052	0.209	0.0605
body composition	lean tissue mass of whole body scan, head excluded	0.40978	0.31362	0.70043	0.503	0.199
body composition	lean tissue mass to body weight ratio	0.030220	0.011049	1.4858	0.0886	0.00942
body composition	percent fat, whole body scan, head excluded	-2.5772	1.2363	-1.2381	0.172	0.0439
body composition	ratio of soft-tissue attenuation coefficients	0.0028049	0.0013639	1.2023	0.184	0.0466
body composition	tissue area	-0.49076	0.15862	-1.3309	0.0502	0.00370
body composition	total tissue mass, whole body scan, head excluded	-0.28719	0.19202	-0.93100	0.370	0.143
clinical blood chemistry	alanine transaminase (plasma ALT)	2.2208	12.505	0.20910	0.961	0.860
clinical blood chemistry	albumin (plasma Alb)	-0.10537	0.57719	-0.099975	0.949	0.856
clinical blood chemistry	alkaline phosphatase (plasma ALP)	-6.1839	14.657	-1.5507	0.835	0.676
clinical blood chemistry	aspartate transaminase (plasma AST)	1.7667	31.044	0.10083	0.985	0.955
clinical blood chemistry	aspartate transaminase to alanine transaminase ratio (plasma AST:ALT)	-0.19650	0.37530	-0.62453	0.872	0.604
clinical blood chemistry	blood urea nitrogen (BUN)	-2.1994	1.3738	-0.88701	0.345	0.125
clinical blood chemistry	calcium (plasma Ca)	-0.11154	0.083104	-0.42553	0.420	0.190
clinical blood chemistry	creatinine (plasma)	-0.010978	0.024230	-0.16934	0.817	0.656
clinical blood chemistry	glucose (plasma GLU, no fast)	-53.818	12.648	-1.4380	0.00324	0.000199
clinical blood chemistry	HDL cholesterol (plasma HDL)	1.8970	2.6923	0.12716	0.754	0.486
clinical blood chemistry	HDL cholesterol to total cholesterol ratio	0.021920	0.012748	1.0715	0.391	0.0962
clinical blood chemistry	phosphorus (plasma phosphate)	-0.021098	0.30843	-0.076313	0.981	0.946
clinical blood chemistry	total bilirubin (plasma TBIL)	-0.011618	0.023713	-0.86656	0.851	0.628
clinical blood chemistry	total cholesterol (plasma CHOL, no fast)	-0.59693	3.6846	-0.33984	0.953	0.872
clinical blood chemistry	total protein (plasma TP)	0.91578	0.75184	0.64609	0.515	0.235
clinical blood chemistry	triglyceride (plasma TG, no fast)	-10.645	7.2051	-0.37640	0.437	0.155
EKG	duration of PQ interval	1.1076	0.91582	1.2926	0.786	0.236
EKG	duration of PR interval	2.0213	0.88616	1.9897	0.469	0.0298
EKG	duration of QRS interval	0.33624	0.44138	0.81268	0.911	0.452
EKG	duration of QT interval	1.4257	0.91419	1.4470	0.644	0.129
EKG	duration of QTC interval, calculated by dividing QT interval by square root of preceding RR interval	0.62227	0.85831	0.74713	0.916	0.474
EKG	duration of RR interval	3.4388	1.7841	1.8966	0.415	0.0631
EKG	duration of ST interval	1.0685	0.84764	1.3020	0.716	0.217
EKG	heart rate coefficient of variation (signal intensity)	0.58821	0.98089	0.55752	0.906	0.553
EKG	heart rate variability, mean of differences between sequential beats; beats per min	3.0420	6.9745	0.42999	0.934	0.666
EKG	heart rate, beats per min	-26.863	13.895	-1.8386	0.384	0.0624
EKG	mean R amplitude, mean amplitude of signal measured from isoelectric line to peak of QRS	0.11167	0.088924	0.74121	0.598	0.219
EKG	mean SR amplitude, mean amplitude of signal measured from signal minimum line to peak of QRS	0.18571	0.10976	0.99737	0.429	0.101
EKG	number of signals	-2.6687	3.8963	-0.59559	0.877	0.499
EKG	proportion of number pairs of successive beat-to-beat intervals that exceed 50 ms	7.2792	4.2139	1.3760	0.791	0.0940
EKG	QT dispersion, measured as inter-lead variability of QT intervals	-3.6862	3.4721	-1.0420	0.893	0.297
EKG	QTc dispersion, calculated as rate-corrected QT dispersion	-4.2824	3.7741	-1.1253	0.873	0.265
EKG	root mean square of successive differences of neighboring RR intervals	-1.8112	2.0561	-0.91512	0.874	0.385
glucose tolerance test	amount glucose injected	3.5335	3.0285	1.2856	0.643	0.259
glucose tolerance test	plasma glucose, 0min	0.58621	11.591	-0.17384	0.981	0.960
glucose tolerance test	plasma glucose, 15min	-99.379	35.336	-2.5107	0.121	0.0115
glucose tolerance test	plasma glucose, 30min	-61.681	35.086	-1.6307	0.394	0.0967
glucose tolerance test	plasma glucose, 60min	-81.303	19.037	-2.5808	0.0227	0.000460
glucose tolerance test	plasma glucose, 120min	25.893	20.063	1.5347	0.523	0.213
grip strength	body weight (at time of grip strength test)	-1.8028	0.55942	-1.3180	0.0163	0.00249
grip strength	forelimb and hindlimb grip strength (mean of trials), average	-23.474	8.9179	-1.3862	0.0632	0.0120
grip strength	forelimb and hindlimb grip strength (mean of trials), average normalized to bw	-1.2498	0.47687	-1.5723	0.0657	0.0123
grip strength	forelimb and hindlimb grip strength by trial, trial1	-43.239	10.127	-2.2518	0.00663	0.000113
grip strength	forelimb and hindlimb grip strength by trial, trial2	-17.027	11.993	-0.83997	0.398	0.163
grip strength	forelimb and hindlimb grip strength by trial, trial3	-27.656	8.0472	-1.4881	0.0247	0.00136
grip strength	forelimb grip strength (mean of trials), average	-10.403	4.0743	-0.97830	0.0968	0.0145
grip strength	forelimb grip strength (mean of trials), average normalized to bw	-0.34942	0.23572	-0.65008	0.395	0.146
grip strength	forelimb grip strength by trial, trial1	0.80277	5.8630	0.36057	0.959	0.892
grip strength	forelimb grip strength by trial, trial2	-13.349	6.3096	-1.1581	0.244	0.0405
grip strength	forelimb grip strength by trial, trial3	-8.0354	5.3348	-0.62340	0.429	0.140
heart weight	heart weight, normalized to body weight	0.42942	0.15120	0.91516	0.0445	0.00650
heart weight	heart weight, weight	11.313	4.0382	1.0820	0.0553	0.00722
hematology	basophil differential (percent of total WBC)	0.13054	0.064194	1.5857	0.401	0.0509
hematology	calculated hemoglobin (cHGB)	-0.10839	0.21085	-0.61983	0.806	0.611
hematology	eosinophil differential (percent of total WBC)	-0.020194	0.22102	0.029405	0.974	0.928
hematology	hematocrit (HCT)	0.30148	0.65994	-0.051960	0.831	0.651
hematology	hemoglobin concentration distribution width (HDW)	0.044721	0.017766	1.1821	0.158	0.0176
hematology	large unstained cells (percent of total WBC)	0.095265	0.083968	0.62461	0.606	0.266
hematology	lymphocyte differential (percent of total WBC)	-2.3734	0.71742	-1.0136	0.0426	0.00245
hematology	mean corpuscular hemoglobin (CHr)	0.010873	0.052775	0.10597	0.921	0.838
hematology	mean platelet volume (MPV)	-0.27025	0.061810	-1.4672	0.00226	0.000136
hematology	mean RBC corpuscular hemoglobin (MCH)	0.33147	0.25929	1.1950	0.561	0.211
hematology	mean RBC corpuscular hemoglobin concentration (MCHC)	0.11308	0.53910	0.27462	0.946	0.835
hematology	mean RBC corpuscular volume (MCV)	0.93531	0.27474	1.4897	0.0178	0.00190
hematology	measured hemoglobin (mHGB)	0.15121	0.37836	0.13097	0.853	0.692
hematology	monocyte differential (percent of total WBC)	-0.22454	0.10785	-0.54680	0.318	0.0460
hematology	neutrophil differential (percent of total WBC)	2.1829	0.56826	1.0748	0.0190	0.000589
hematology	platelet count (PLT; units per volume x 10³)	-72.639	43.600	-0.88487	0.450	0.106
hematology	RBC corpuscular distribution width (RDW)	0.43084	0.11418	1.3002	0.0173	0.000709
hematology	RBC corpuscular hemoglobin concentration mean (CHCM)	-0.39068	0.19287	-1.0791	0.198	0.0518
hematology	red blood cell count (RBC; per volume x 10⁶)	-0.12716	0.15116	-0.84827	0.664	0.407
hematology	reticulocyte count (Retic; units per volume x 10⁹)	-15.537	17.727	-0.58447	0.745	0.388
hematology	reticulocyte differential (percent of total RBC)	-0.095943	0.17432	-0.19198	0.832	0.586
hematology	white blood cell count (WBC; units per volume x 10³)	-1.1765	0.49240	-0.64140	0.0991	0.0234
holeboard	number of hole pokes by individual hole number, 20 min test, 1	-1.5103	0.82105	-1.4461	0.500	0.0741
holeboard	number of hole pokes by individual hole number, 20 min test, 2	-0.40000	0.54193	-0.51185	0.860	0.465
holeboard	number of hole pokes by individual hole number, 20 min test, 3	0.36791	0.36395	0.69637	0.794	0.319
holeboard	number of hole pokes by individual hole number, 20 min test, 4	-0.81517	0.93289	-0.75121	0.792	0.388
holeboard	number of hole pokes by individual hole number, 20 min test, 5	-0.71531	0.31229	-1.0740	0.410	0.0280
holeboard	number of hole pokes by individual hole number, 20 min test, 6	-0.38201	0.31814	-1.0926	0.834	0.238
holeboard	number of hole pokes by individual hole number, 20 min test, 7	-0.10378	0.28938	-0.30467	0.971	0.722
holeboard	number of hole pokes by individual hole number, 20 min test, 8	-0.020690	0.44696	0.11079	0.989	0.963
holeboard	number of hole pokes by individual hole number, 20 min test, 9	0.33425	0.30434	0.71972	0.758	0.279
holeboard	number of hole pokes by individual hole number, 20 min test, 10	-0.13931	0.24222	-0.31997	0.930	0.569
holeboard	number of hole pokes by individual hole number, 20 min test, 11	-0.80143	0.66588	-2.0926	0.805	0.237
holeboard	number of hole pokes by individual hole number, 20 min test, 12	-0.095556	0.40613	-0.048938	0.960	0.815
holeboard	number of hole pokes by individual hole number, 20 min test, 13	-0.011212	0.66572	0.067524	0.999	0.987
holeboard	number of hole pokes by individual hole number, 20 min test, 14	0.15901	0.38965	0.34403	0.906	0.686
holeboard	number of hole pokes by individual hole number, 20 min test, 15	-0.20301	0.50550	-0.22973	0.903	0.690
holeboard	number of hole pokes by individual hole number, 20 min test, 16	0.21579	0.75474	0.21935	0.938	0.777
holeboard	total number of hole pokes, 20 min test	-2.2772	3.7891	-0.21244	0.768	0.552
light / dark	fecal boli count, 20 min test	1.6879	0.75652	1.6754	0.360	0.0322
light / dark	latency to enter dark zone, 20 min test	-98.619	90.188	-1.8857	0.689	0.282
light / dark	number of transitions between light and dark zones, 20 min test	34.202	10.613	2.4567	0.0590	0.00275
light / dark	percentage of total time in dark zone, 20 min test	-4.0952	6.6689	-0.61866	0.811	0.543
light / dark	percentage of total time in light zone, 20 min test	4.0952	6.6689	0.61539	0.809	0.543
light / dark	time mobile in dark zone, 20 min test	62.827	17.321	2.2120	0.0189	0.000929
light / dark	time mobile in light zone, 20 min test	77.103	15.150	2.5495	0.000757	0.0000123
light / dark	time spent in dark zone, 20 min test	-42.677	78.661	-0.42480	0.871	0.591
light / dark	time spent in light zone, 20 min test	42.677	78.661	0.42480	0.871	0.591
open field	average speed in center of arena, 20 min test	2.9096	0.44515	2.6288	0.0000121	4.53e-8
open field	average speed in periphery of arena, 20 min test	1.6372	0.17239	2.4878	4.68e-10	2.05e-12
open field	distance traveled habituation ratio, 20 min test	-74.261	9.4241	-3.0697	1.38e-7	4.45e-10
open field	distance traveled in center of arena, 20 min test	401.77	105.88	1.7549	0.00781	0.000439
open field	distance traveled in periphery of arena, 20 min test	1721.5	175.85	2.5884	2.48e-10	7.97e-13
open field	distance traveled slope, 20 min test	-72.949	9.1155	-3.0697	1.09e-7	2.93e-10
open field	distance traveled, 20 min test, 1st 5min	954.53	90.849	2.7848	2.20e-11	8.25e-14
open field	distance traveled, 20 min test, 2nd 5min	543.18	63.656	2.4878	1.17e-8	4.90e-11
open field	distance traveled, 20 min test, 3rd 5min	315.46	65.181	2.0575	0.000649	0.0000157
open field	distance traveled, 20 min test, 4th 5min	286.17	50.929	1.9218	0.0000691	0.00000107
open field	number of clockwise revolution episodes, 20 min test	7.6409	1.3259	2.2468	0.0000873	6.55e-7
open field	number of counter-clockwise revolution episodes, 20 min test	7.9685	1.7205	2.2641	0.00186	0.0000299
open field	number of fecal boli, 20 min test	1.3471	0.91370	1.2303	0.465	0.149
open field	number of rears in 5 min bins, 20 min test, 1st 5min	5.4411	2.8147	1.2417	0.242	0.0595
open field	number of rears in 5 min bins, 20 min test, 2nd 5min	3.1150	2.2911	0.45492	0.465	0.181
open field	number of rears in 5 min bins, 20 min test, 3rd 5min	1.4167	2.4776	0.020812	0.775	0.570
open field	number of rears in 5 min bins, 20 min test, 4th 5min	-1.8027	2.3850	-0.73781	0.702	0.454
open field	percentage of total time in center of arena, 20 min test	-0.64239	2.1745	-0.35720	0.913	0.769
open field	percentage of total time in center of arena, slope, 20 min test	-1.7642	1.1081	-0.81588	0.574	0.118
open field	percentage of total time in center, habituation ratio, 20 min test	-1.9452	1.1243	-0.88132	0.531	0.0904
open field	percentage of total time in corners of arena, 20 min test	-0.014707	2.8382	0.31882	0.999	0.996
open field	percentage of total time in corners, habituation ratio, 20 min test	5.9645	1.4482	2.0922	0.0667	0.000161
open field	percentage of total time in corners, slope, 20 min test	5.6651	1.4597	2.0357	0.0865	0.000337
open field	permanence time in center of arena, 20 min test	-7.6955	26.095	-0.35863	0.913	0.769
open field	permanence time in corners of arena, 20 min test	-0.16995	34.060	0.31882	0.998	0.996
open field	permanence time in periphery of arena, 20 min test	7.6657	26.101	0.35720	0.913	0.770
open field	total distance traveled, 20 min test	2148.2	226.22	2.5186	4.79e-10	2.05e-12
open field	total number of rears, 20 min test	10.201	8.3352	0.34863	0.474	0.227
open field	whole arena average speed, 20 min test	1.7899	0.18849	2.5186	4.79e-10	2.05e-12
open field	whole arena resting time, 20 min test	-155.67	18.280	-2.3400	9.70e-9	5.20e-11
open field	whole arena time spent mobile, 20 min test	155.41	18.278	2.4324	1.01e-8	5.43e-11
open field	whole arena time spent vertical, 20 min test	1.3494	9.1121	-0.0033565	0.955	0.883
SHIRPA	locomotor activity (number of squares in the arena the mouse moves into with all four paws in first 30 s of test)	10.183	1.9210	2.7545	0.000901	0.00000424
startle / PPI	average baseline movement during background noise	0.65399	0.77104	0.50314	0.852	0.400
startle / PPI	average of each corrected maximum percent pre-pulse inhibition value	-0.040380	0.057327	-0.47942	0.778	0.484
startle / PPI	average of each corrected percent pre-pulse inhibition value	-0.042718	0.053261	-0.49105	0.749	0.426
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-0.025131	6.7309	0.048358	0.999	0.997
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-1.3153	5.2020	-0.17391	0.942	0.801
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-2.0708	5.1528	-0.32288	0.884	0.689
startle / PPI	average startle response to full pulse (120 dB)	104.26	26.953	1.6866	0.00507	0.000312
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	116.85	29.471	1.7743	0.00441	0.000229
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	89.696	27.410	1.5564	0.0193	0.00192
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	70.620	23.388	1.4936	0.0351	0.00395
startle / PPI	average startle response to pre-pulse, 74dB sound pressure level	-0.055564	1.0687	0.042748	0.993	0.959
startle / PPI	average startle response to pre-pulse, 78dB sound pressure level	1.3465	0.93293	0.79424	0.656	0.155
startle / PPI	average startle response to pre-pulse, 82dB sound pressure level	1.8149	1.3456	0.63671	0.628	0.183
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	0.00082086	0.072901	0.041345	0.998	0.991
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-0.022173	0.055142	-0.29676	0.888	0.689
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-0.042881	0.057883	-0.52183	0.714	0.462
startle / PPI	corrected average startle response to full pulse (120 dB) minus average baseline movement during background noise	103.56	27.114	1.6866	0.00571	0.000364
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 74dB sound pressure level	116.90	29.745	1.7949	0.00445	0.000256
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 78dB sound pressure level	89.241	27.378	1.5517	0.0194	0.00199
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 82dB sound pressure level	70.428	23.415	1.5243	0.0344	0.00408
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-0.0086119	0.083027	-0.055373	0.993	0.918
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-0.0088253	0.057418	-0.15767	0.956	0.878
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-0.043967	0.060696	-0.50265	0.706	0.472
startle / PPI	corrected maximum startle response to full pulse (120 dB) minus maximum baseline movement during background noise	443.88	109.36	1.8464	0.00349	0.000170
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 74dB sound pressure level	494.44	118.02	1.9479	0.00258	0.000111
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 78dB sound pressure level	386.55	117.12	1.7543	0.0184	0.00179
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 82dB sound pressure level	279.18	90.029	1.5852	0.0286	0.00314
startle / PPI	maximum baseline movement during background noise	1.6202	1.9068	0.56126	0.815	0.399
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-1.3897	7.8449	-0.10598	0.988	0.860
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-0.30573	5.5367	-0.11021	0.983	0.956
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-2.8586	5.6726	-0.40372	0.820	0.616
startle / PPI	maximum startle response to full pulse (120 dB)	445.56	109.11	1.8700	0.00322	0.000157
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	495.70	117.22	1.9479	0.00239	0.0000975
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	390.38	117.25	1.7675	0.0173	0.00164
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	280.47	90.082	1.5952	0.0278	0.00303
startle / PPI	maximum startle response to pre-pulse, 74dB sound pressure level	1.2642	2.8824	0.50951	0.925	0.663
startle / PPI	maximum startle response to pre-pulse, 78dB sound pressure level	3.2606	1.8804	0.84322	0.582	0.0891
startle / PPI	maximum startle response to pre-pulse, 82dB sound pressure level	4.1130	3.2283	0.55471	0.591	0.209

MULTIPLE (CATEGORICAL) TRAIT PROFILE PLOT — Early Adult Phenotyping study (EAP)

Procedure	JaxKOMP-EAP Trait	Trait Effect	P-value
eye morphology	anterior chamber depth	1.0 %	1.0
eye morphology	bulging eye	1.0 %	1.00
eye morphology	cornea	3.0 %	1.00
eye morphology	cornea opacity	4.0 %	0.448
eye morphology	cornea vascularization	2.0 %	1.0
eye morphology	corneal deposits	1.0 %	1.00
eye morphology	corneal mineralization	1.0 %	1.00
eye morphology	corneal scleralization	12.0 %	0.00264
eye morphology	corneal ulcer	1.0 %	1.00
eye morphology	eye closure	1.0 %	1.00
eye morphology	eye hemorrhage or blood presence	1.0 %	1.0
eye morphology	eyelid morphology	12.0 %	0.0000794
eye morphology	eyes (present, absent)	0.0 %	1.00
eye morphology	fusion between cornea and lens	3.0 %	1.0
eye morphology	iris pigmentation	23.0 %	8.41e-8
eye morphology	iris transillumination	1.0 %	1.0
eye morphology	irispupil	3.0 %	1.0
eye morphology	lacrimation	6.0 %	0.114
eye morphology	lens	9.0 %	1.00
eye morphology	lens opacity	16.0 %	0.0170
eye morphology	narrow eye opening	5.0 %	0.152
eye morphology	optic disc	6.0 %	0.0757
eye morphology	persistence of hyaloid vascular system	8.0 %	0.154
eye morphology	pupil dilation	2.0 %	1.00
eye morphology	pupil light response	2.0 %	1.0
eye morphology	pupil position	4.0 %	1.0
eye morphology	pupil shape	3.0 %	1.0
eye morphology	retina	7.0 %	0.902
eye morphology	retinal blood vessels	3.0 %	1.00
eye morphology	retinal blood vessels pattern	4.0 %	1.00
eye morphology	retinal blood vessels structure	3.0 %	1.0
eye morphology	retinal pigmentation	7.0 %	0.815
eye morphology	retinal structure	3.0 %	1.0
eye morphology	synechia	3.0 %	1.00
eye morphology	vitreous	3.0 %	1.0
SHIRPA	activity body position	17.0 %	0.000700
SHIRPA	aggression	1.0 %	1.0
SHIRPA	body length	0.0 %	1.00
SHIRPA	body position	0.0 %	1.0
SHIRPA	body thickness	0.0 %	1.00
SHIRPA	coat color abdomen	4.0 %	1.0
SHIRPA	coat color back	0.0 %	1.00
SHIRPA	coat color head	0.0 %	1.00
SHIRPA	coat color pattern abdomen	1.0 %	1.0
SHIRPA	coat color pattern back	0.0 %	1.0
SHIRPA	coat color pattern head	0.0 %	1.00
SHIRPA	coat hair abdomen texture appearance	2.0 %	1.0
SHIRPA	coat hair back texture appearance	0.0 %	1.0
SHIRPA	coat hair distribution abdomen	1.0 %	1.0
SHIRPA	coat hair distribution back	0.0 %	1.0
SHIRPA	coat hair distribution head	1.0 %	1.0
SHIRPA	coat hair head texture appearance	0.0 %	1.0
SHIRPA	contact righting	5.0 %	1.0
SHIRPA	ear morphology	0.0 %	1.0
SHIRPA	fat distribution	0.0 %	1.0
SHIRPA	forelimb digit number	0.0 %	1.0
SHIRPA	forelimb digit position	0.0 %	1.0
SHIRPA	forelimb digit shape	0.0 %	1.0
SHIRPA	forelimb digit size	0.0 %	1.0
SHIRPA	forelimb footpads	0.0 %	1.0
SHIRPA	forelimb nail length	0.0 %	1.0
SHIRPA	forelimb nail number	0.0 %	1.0
SHIRPA	forelimb nail position	0.0 %	1.0
SHIRPA	forelimb nail shape	0.0 %	1.0
SHIRPA	forelimbs position	0.0 %	1.0
SHIRPA	forelimbs shape	0.0 %	1.0
SHIRPA	forelimbs size	0.0 %	1.00
SHIRPA	forepaw position	0.0 %	1.0
SHIRPA	forepaw shape	0.0 %	1.0
SHIRPA	forepaw size	0.0 %	1.0
SHIRPA	gait (fluidity)	0.0 %	1.0
SHIRPA	genitalia morphology	0.0 %	1.0
SHIRPA	genitalia presence	0.0 %	1.0
SHIRPA	genitalia size	0.0 %	1.0
SHIRPA	head bobbing	0.0 %	1.0
SHIRPA	head morphology	0.0 %	1.00
SHIRPA	head size	0.0 %	1.0
SHIRPA	hindlimb digit number	0.0 %	1.0
SHIRPA	hindlimb digit position	0.0 %	1.0
SHIRPA	hindlimb digit shape	0.0 %	1.0
SHIRPA	hindlimb digit size	0.0 %	1.0
SHIRPA	hindlimb nail length	0.0 %	1.0
SHIRPA	hindlimb nail number	0.0 %	1.0
SHIRPA	hindlimb nail position	0.0 %	1.0
SHIRPA	hindlimb nail shape	0.0 %	1.0
SHIRPA	hindlimbs footpads	0.0 %	1.0
SHIRPA	hindlimbs position	0.0 %	1.0
SHIRPA	hindlimbs shape	0.0 %	1.0
SHIRPA	hindlimbs size	0.0 %	1.0
SHIRPA	hindpaw position	0.0 %	1.0
SHIRPA	hindpaw shape	0.0 %	1.0
SHIRPA	hindpaw size	0.0 %	1.0
SHIRPA	limb grasp	10.0 %	0.123
SHIRPA	lower lip morphology	0.0 %	1.0
SHIRPA	lower teeth appearance	0.0 %	1.00
SHIRPA	mouth morphology	0.0 %	1.0
SHIRPA	salivation	0.0 %	1.0
SHIRPA	skin color back paws	0.0 %	1.0
SHIRPA	skin color ear	0.0 %	1.0
SHIRPA	skin color front paws	0.0 %	1.0
SHIRPA	skin color snout	0.0 %	1.0
SHIRPA	skin color tail	0.0 %	1.0
SHIRPA	skin color whole body	0.0 %	1.0
SHIRPA	skin texture back paw	0.0 %	1.0
SHIRPA	skin texture ear	0.0 %	1.0
SHIRPA	skin texture front paws	0.0 %	1.0
SHIRPA	skin texture snout	0.0 %	1.0
SHIRPA	skin texture tail	0.0 %	1.0
SHIRPA	skin texture whole body	0.0 %	1.00
SHIRPA	snout size	0.0 %	1.0
SHIRPA	startle response	0.0 %	1.0
SHIRPA	tail curvature	0.0 %	1.0
SHIRPA	tail elevation	22.0 %	0.000102
SHIRPA	tail length	0.0 %	1.00
SHIRPA	tail morphology	0.0 %	1.00
SHIRPA	tail presence	0.0 %	1.0
SHIRPA	tail shape	0.0 %	1.00
SHIRPA	tail thickness	0.0 %	1.0
SHIRPA	teeth presence	0.0 %	1.00
SHIRPA	transfer arousal	1.0 %	1.0
SHIRPA	tremor	0.0 %	1.0
SHIRPA	trunk curl	0.0 %	1.0
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	0.0 %	1.0
SHIRPA	upper lip morphology	0.0 %	1.0
SHIRPA	upper teeth appearance	0.0 %	1.00
SHIRPA	vibrissae appearance	1.0 %	1.0
SHIRPA	vibrissae presence	2.0 %	1.0
SHIRPA	vocalization	2.0 %	1.0

GENOTYPE CORRELATION PLOT

Correlate Epb41l1^{tm1b(EUCOMM)Wtsi} -/- with genotype: