MPD: JaxKOMP-EAP genotype: Enpp5<sup>tm1b(KOMP)Mbp</sup>/2J -/-

JaxKOMP-EAP effect sizes: Enpp5^{tm1b(KOMP)Mbp}/2J -/- Gene Enpp5

MULTIPLE (NUMERIC) TRAIT PROFILE PLOT — Early Adult Phenotyping study (EAP)

In this plot, data points are the computed genotype effect size vs. C57BL/6NJ controls, for all measured numeric phenotypes in JaxKOMP-EAP

Dimensions Width: × Height: px

Plot Options Group by Procedure Standard Error Show Effect Sizes RankZ

Significance Threshold p-Value Threshold Adjusted Unadjusted

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Procedure	JaxKOMP-EAP Trait	Trait Effect	Trait Effect SE	Trait Effect RankZ	Adjusted p-value	Unadjusted p-value

ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 6 kHz pip	0.97426	1.6438	0.015847	0.858	0.575
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 12 kHz pip	2.1508	2.8130	0.52717	0.831	0.473
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 18 kHz pip	3.7304	2.1964	0.57311	0.501	0.140
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 24 kHz pip	-0.19776	3.9859	-0.15046	0.987	0.962
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 30 kHz pip	-1.3340	5.8391	-0.24640	0.934	0.827
body composition	body length	-0.076179	0.052234	-0.67148	0.433	0.154
body composition	body weight (at time of DXA)	-1.1224	0.70913	-0.70434	0.303	0.123
body composition	bone area, whole body scan, head excluded	0.32361	0.18113	1.5419	0.293	0.0832
body composition	bone mineral content of whole body scan, head excluded	0.023998	0.013960	1.5199	0.313	0.0950
body composition	bone mineral content to body weight ratio	0.0013902	0.00055191	1.8656	0.105	0.0166
body composition	bone mineral density of whole body scan, head excluded	0.00085366	0.00061277	0.96488	0.460	0.173
body composition	fat tissue mass of whole body scan, head excluded	-0.67299	0.39871	-1.2469	0.306	0.101
body composition	fat tissue mass to body weight ratio	-0.018559	0.014068	-0.83425	0.422	0.196
body composition	lean tissue mass of whole body scan, head excluded	0.43581	0.36011	0.75197	0.536	0.235
body composition	lean tissue mass to body weight ratio	0.039174	0.013150	1.8065	0.0590	0.00531
body composition	percent fat, whole body scan, head excluded	-2.0920	1.3248	-1.0120	0.324	0.124
body composition	ratio of soft-tissue attenuation coefficients	0.0023181	0.0014874	1.0106	0.331	0.128
body composition	tissue area	-0.29761	0.15927	-0.81618	0.293	0.0706
body composition	total tissue mass, whole body scan, head excluded	-0.25146	0.16892	-0.82654	0.373	0.146
clinical blood chemistry	alanine transaminase (plasma ALT)	-20.682	10.579	-1.5008	0.373	0.0582
clinical blood chemistry	albumin (plasma Alb)	-0.63664	0.54190	-0.79694	0.566	0.248
clinical blood chemistry	alkaline phosphatase (plasma ALP)	0.94991	12.036	-0.35973	0.967	0.938
clinical blood chemistry	aspartate transaminase (plasma AST)	-37.643	25.214	-1.5599	0.456	0.144
clinical blood chemistry	aspartate transaminase to alanine transaminase ratio (plasma AST:ALT)	-0.046733	0.32136	-0.12809	0.967	0.885
clinical blood chemistry	blood urea nitrogen (BUN)	0.71821	0.98472	0.24389	0.714	0.470
clinical blood chemistry	calcium (plasma Ca)	-0.32175	0.095000	-1.8171	0.0217	0.00169
clinical blood chemistry	creatinine (plasma)	0.022044	0.018211	0.66109	0.486	0.234
clinical blood chemistry	glucose (plasma GLU, no fast)	-57.146	9.9805	-1.5281	0.000118	0.00000148
clinical blood chemistry	HDL cholesterol (plasma HDL)	-3.0150	2.6054	-0.96931	0.557	0.255
clinical blood chemistry	HDL cholesterol to total cholesterol ratio	0.011029	0.0098857	0.45112	0.610	0.272
clinical blood chemistry	phosphorus (plasma phosphate)	-0.39544	0.34561	-0.69204	0.549	0.260
clinical blood chemistry	total bilirubin (plasma TBIL)	-0.019453	0.0087575	-1.3233	0.213	0.0327
clinical blood chemistry	total cholesterol (plasma CHOL, no fast)	-4.4356	2.8552	-0.95352	0.408	0.129
clinical blood chemistry	total protein (plasma TP)	-0.58961	0.58729	-0.51264	0.598	0.322
clinical blood chemistry	triglyceride (plasma TG, no fast)	-0.61818	6.2983	0.18126	0.964	0.922
EKG	duration of PQ interval	-0.98083	0.74107	-0.89690	0.762	0.193
EKG	duration of PR interval	-0.86224	0.82325	-0.74980	0.845	0.301
EKG	duration of QRS interval	0.18635	0.31522	0.35812	0.945	0.558
EKG	duration of QT interval	0.18875	0.54715	0.34953	0.944	0.732
EKG	duration of QTC interval, calculated by dividing QT interval by square root of preceding RR interval	0.49537	0.52509	0.60525	0.871	0.351
EKG	duration of RR interval	-0.89750	1.0366	-0.20700	0.780	0.392
EKG	duration of ST interval	-0.020833	0.60401	0.18850	0.989	0.973
EKG	heart rate coefficient of variation (signal intensity)	0.33449	1.0031	0.36026	0.960	0.741
EKG	heart rate variability, mean of differences between sequential beats; beats per min	2.8579	7.1687	0.40580	0.937	0.692
EKG	heart rate, beats per min	6.2470	8.4946	0.10201	0.794	0.466
EKG	mean R amplitude, mean amplitude of signal measured from isoelectric line to peak of QRS	0.089753	0.073668	0.59012	0.602	0.230
EKG	mean SR amplitude, mean amplitude of signal measured from signal minimum line to peak of QRS	0.15099	0.097380	0.80650	0.477	0.129
EKG	number of signals	-0.68333	3.1504	-0.19055	0.965	0.829
EKG	proportion of number pairs of successive beat-to-beat intervals that exceed 50 ms	8.1970	4.3223	1.4833	0.758	0.0651
EKG	QT dispersion, measured as inter-lead variability of QT intervals	-5.1654	3.1427	-1.4527	0.858	0.108
EKG	QTc dispersion, calculated as rate-corrected QT dispersion	-5.4535	3.3018	-1.4133	0.835	0.107
EKG	root mean square of successive differences of neighboring RR intervals	-2.3063	1.9171	-1.2089	0.843	0.236
glucose tolerance test	amount glucose injected	-1.7449	1.3784	-0.16645	0.590	0.212
glucose tolerance test	plasma glucose, 0min	0.60988	4.4587	-0.16966	0.951	0.892
glucose tolerance test	plasma glucose, 15min	-33.367	22.778	-0.79782	0.451	0.149
glucose tolerance test	plasma glucose, 30min	-22.938	19.757	-0.59145	0.584	0.251
glucose tolerance test	plasma glucose, 60min	-16.539	14.884	-0.57518	0.602	0.272
glucose tolerance test	plasma glucose, 120min	-2.4631	11.291	-0.31107	0.933	0.828
grip strength	body weight (at time of grip strength test)	1.1380	0.50598	1.2176	0.108	0.0320
grip strength	forelimb and hindlimb grip strength (mean of trials), average	-11.595	6.8418	-0.58160	0.258	0.101
grip strength	forelimb and hindlimb grip strength (mean of trials), average normalized to bw	-0.40519	0.29462	-0.39488	0.367	0.179
grip strength	forelimb and hindlimb grip strength by trial, trial1	-27.746	9.8916	-1.5104	0.0770	0.00889
grip strength	forelimb and hindlimb grip strength by trial, trial2	15.250	10.359	1.1525	0.383	0.151
grip strength	forelimb and hindlimb grip strength by trial, trial3	-2.0281	11.759	0.081417	0.942	0.864
grip strength	forelimb grip strength (mean of trials), average	-4.5459	6.5080	-0.30834	0.730	0.490
grip strength	forelimb grip strength (mean of trials), average normalized to bw	-0.42869	0.28808	-0.84826	0.395	0.147
grip strength	forelimb grip strength by trial, trial1	-11.281	8.0520	-0.99961	0.503	0.172
grip strength	forelimb grip strength by trial, trial2	-0.92711	8.7716	0.11937	0.967	0.917
grip strength	forelimb grip strength by trial, trial3	-15.305	8.8177	-1.2835	0.354	0.0932
heart weight	heart weight, normalized to body weight	0.18265	0.12598	0.19790	0.348	0.154
heart weight	heart weight, weight	5.7567	3.1973	0.38132	0.235	0.0781
hematology	basophil differential (percent of total WBC)	0.017006	0.053144	0.29669	0.934	0.751
hematology	calculated hemoglobin (cHGB)	-0.050076	0.57962	-0.44156	0.971	0.932
hematology	eosinophil differential (percent of total WBC)	0.24494	0.21110	0.75801	0.644	0.254
hematology	hematocrit (HCT)	0.76193	1.9610	0.49051	0.852	0.700
hematology	hemoglobin concentration distribution width (HDW)	0.010695	0.025746	0.29087	0.855	0.680
hematology	large unstained cells (percent of total WBC)	0.081504	0.14201	0.52620	0.824	0.570
hematology	lymphocyte differential (percent of total WBC)	-0.85110	0.82257	-0.40142	0.561	0.308
hematology	mean corpuscular hemoglobin (CHr)	-0.10225	0.064395	-0.82324	0.318	0.121
hematology	mean platelet volume (MPV)	0.021064	0.091402	-0.030875	0.916	0.819
hematology	mean RBC corpuscular hemoglobin (MCH)	-0.69900	0.78564	-1.3429	0.724	0.379
hematology	mean RBC corpuscular hemoglobin concentration (MCHC)	-1.6478	1.6945	-1.5313	0.686	0.337
hematology	mean RBC corpuscular volume (MCV)	0.28983	0.26469	0.53888	0.513	0.281
hematology	measured hemoglobin (mHGB)	-0.72647	0.97062	-1.4261	0.708	0.459
hematology	monocyte differential (percent of total WBC)	0.049484	0.12808	0.38517	0.895	0.701
hematology	neutrophil differential (percent of total WBC)	0.64536	0.69485	0.34137	0.589	0.359
hematology	platelet count (PLT; units per volume x 10³)	65.980	65.157	0.91769	0.668	0.318
hematology	RBC corpuscular distribution width (RDW)	0.12162	0.14471	0.41524	0.646	0.406
hematology	RBC corpuscular hemoglobin concentration mean (CHCM)	-0.46976	0.16558	-1.2429	0.0584	0.00734
hematology	red blood cell count (RBC; per volume x 10⁶)	0.086884	0.42880	0.035582	0.927	0.841
hematology	reticulocyte count (Retic; units per volume x 10⁹)	-7.7492	18.704	-0.25335	0.901	0.681
hematology	reticulocyte differential (percent of total RBC)	-0.11450	0.15021	-0.28126	0.761	0.451
hematology	white blood cell count (WBC; units per volume x 10³)	-1.5353	0.38289	-0.85691	0.00507	0.000293
holeboard	number of hole pokes by individual hole number, 20 min test, 1	-0.68171	0.92974	-0.63734	0.823	0.471
holeboard	number of hole pokes by individual hole number, 20 min test, 2	0.63845	0.57184	1.1689	0.775	0.275
holeboard	number of hole pokes by individual hole number, 20 min test, 3	-0.18636	0.48231	-0.22555	0.937	0.702
holeboard	number of hole pokes by individual hole number, 20 min test, 4	-0.048864	0.78418	0.044746	0.987	0.951
holeboard	number of hole pokes by individual hole number, 20 min test, 5	-0.23396	0.55801	-0.26382	0.935	0.679
holeboard	number of hole pokes by individual hole number, 20 min test, 6	-0.0068181	0.28763	0.018556	1.00	0.981
holeboard	number of hole pokes by individual hole number, 20 min test, 7	-0.26046	0.22261	-0.72579	0.831	0.253
holeboard	number of hole pokes by individual hole number, 20 min test, 8	-0.27273	0.51040	-0.34159	0.913	0.598
holeboard	number of hole pokes by individual hole number, 20 min test, 9	0.38864	0.55316	0.79859	0.878	0.489
holeboard	number of hole pokes by individual hole number, 20 min test, 10	-0.23636	0.28571	-0.56481	0.870	0.416
holeboard	number of hole pokes by individual hole number, 20 min test, 11	-0.33977	0.34849	-0.90290	0.823	0.339
holeboard	number of hole pokes by individual hole number, 20 min test, 12	-0.093182	0.44723	-0.045560	0.960	0.837
holeboard	number of hole pokes by individual hole number, 20 min test, 13	0.089160	1.0524	0.18148	0.988	0.933
holeboard	number of hole pokes by individual hole number, 20 min test, 14	-0.22179	0.33789	-0.24360	0.848	0.518
holeboard	number of hole pokes by individual hole number, 20 min test, 15	-0.43295	0.44747	-0.60514	0.778	0.343
holeboard	number of hole pokes by individual hole number, 20 min test, 16	0.031993	0.63573	0.047249	0.981	0.960
holeboard	total number of hole pokes, 20 min test	-0.66681	4.6217	0.0016868	0.947	0.886
light / dark	fecal boli count, 20 min test	1.5375	0.81200	1.5627	0.419	0.0641
light / dark	latency to enter dark zone, 20 min test	105.79	77.160	1.6228	0.605	0.176
light / dark	number of transitions between light and dark zones, 20 min test	-11.292	8.5067	-1.0275	0.515	0.190
light / dark	percentage of total time in dark zone, 20 min test	-5.5560	5.7445	-0.85870	0.682	0.338
light / dark	percentage of total time in light zone, 20 min test	5.5560	5.7445	0.85675	0.682	0.338
light / dark	time mobile in dark zone, 20 min test	-15.966	15.081	-1.0413	0.595	0.295
light / dark	time mobile in light zone, 20 min test	5.1239	10.804	0.11381	0.818	0.637
light / dark	time spent in dark zone, 20 min test	-122.24	68.065	-1.4953	0.439	0.0786
light / dark	time spent in light zone, 20 min test	122.24	68.065	1.4953	0.439	0.0786
open field	average speed in center of arena, 20 min test	-0.80829	0.46738	-1.6363	0.377	0.0899
open field	average speed in periphery of arena, 20 min test	-0.069113	0.13520	-0.77172	0.782	0.612
open field	distance traveled habituation ratio, 20 min test	24.752	7.7535	1.8284	0.0485	0.00244
open field	distance traveled in center of arena, 20 min test	66.769	78.853	0.079970	0.647	0.401
open field	distance traveled in periphery of arena, 20 min test	-266.31	150.28	-1.5030	0.253	0.0826
open field	distance traveled slope, 20 min test	22.467	7.7155	1.7871	0.0819	0.00535
open field	distance traveled, 20 min test, 1st 5min	-200.08	67.716	-1.7612	0.0386	0.00476
open field	distance traveled, 20 min test, 2nd 5min	-32.705	55.715	-0.87934	0.763	0.560
open field	distance traveled, 20 min test, 3rd 5min	5.2583	47.239	-0.36150	0.971	0.912
open field	distance traveled, 20 min test, 4th 5min	26.987	49.196	-0.14212	0.776	0.586
open field	number of clockwise revolution episodes, 20 min test	0.59535	1.2444	-0.049723	0.862	0.634
open field	number of counter-clockwise revolution episodes, 20 min test	-0.27780	1.2234	-0.57452	0.921	0.821
open field	number of fecal boli, 20 min test	1.7625	0.92845	1.5251	0.301	0.0634
open field	number of rears in 5 min bins, 20 min test, 1st 5min	-4.4757	2.0665	-1.4133	0.181	0.0352
open field	number of rears in 5 min bins, 20 min test, 2nd 5min	-2.8000	2.0402	-1.0435	0.460	0.176
open field	number of rears in 5 min bins, 20 min test, 3rd 5min	-2.4610	2.1661	-0.86559	0.539	0.261
open field	number of rears in 5 min bins, 20 min test, 4th 5min	-4.5625	2.3693	-1.3054	0.262	0.0598
open field	percentage of total time in center of arena, 20 min test	6.9667	2.6260	1.3278	0.139	0.0107
open field	percentage of total time in center of arena, slope, 20 min test	0.64225	1.5333	0.48641	0.932	0.677
open field	percentage of total time in center, habituation ratio, 20 min test	0.36937	1.6393	0.31882	0.957	0.823
open field	percentage of total time in corners of arena, 20 min test	-6.7032	3.1789	-0.95924	0.239	0.0400
open field	percentage of total time in corners, habituation ratio, 20 min test	2.8544	1.8997	0.96564	0.626	0.139
open field	percentage of total time in corners, slope, 20 min test	2.4881	1.7956	0.85780	0.652	0.172
open field	permanence time in center of arena, 20 min test	83.579	31.513	1.3278	0.139	0.0107
open field	permanence time in corners of arena, 20 min test	-80.445	38.148	-0.95924	0.239	0.0400
open field	permanence time in periphery of arena, 20 min test	-83.564	31.508	-1.3278	0.139	0.0107
open field	total distance traveled, 20 min test	-160.00	187.85	-0.95076	0.614	0.399
open field	total number of rears, 20 min test	-14.688	6.9264	-1.3409	0.177	0.0389
open field	whole arena average speed, 20 min test	-0.13362	0.15669	-0.95076	0.613	0.398
open field	whole arena resting time, 20 min test	3.2478	18.492	0.65731	0.922	0.861
open field	whole arena time spent mobile, 20 min test	-3.2471	18.494	-0.68591	0.924	0.861
open field	whole arena time spent vertical, 20 min test	-24.887	7.5901	-1.8213	0.0321	0.00190
SHIRPA	locomotor activity (number of squares in the arena the mouse moves into with all four paws in first 30 s of test)	-1.7319	1.6093	-0.52829	0.598	0.291
startle / PPI	average baseline movement during background noise	-0.32492	0.72827	-0.15970	0.925	0.657
startle / PPI	average of each corrected maximum percent pre-pulse inhibition value	0.034224	0.065261	0.20387	0.822	0.602
startle / PPI	average of each corrected percent pre-pulse inhibition value	0.036601	0.062525	0.28360	0.829	0.561
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-0.024668	7.2364	0.049761	0.999	0.997
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	4.9387	6.2881	0.43894	0.741	0.436
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	6.8285	6.5865	0.61794	0.603	0.305
startle / PPI	average startle response to full pulse (120 dB)	44.561	23.755	1.0567	0.215	0.0665
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	40.980	23.324	0.94346	0.252	0.0850
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	22.536	21.224	0.65918	0.513	0.293
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	5.7061	17.587	0.33916	0.857	0.747
startle / PPI	average startle response to pre-pulse, 74dB sound pressure level	-0.58958	0.84810	-0.39008	0.869	0.490
startle / PPI	average startle response to pre-pulse, 78dB sound pressure level	-0.10539	1.0979	-0.039943	0.989	0.924
startle / PPI	average startle response to pre-pulse, 82dB sound pressure level	2.5000	1.4017	0.89431	0.480	0.0806
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	0.00049232	0.079742	0.035737	0.998	0.995
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	0.047274	0.068352	0.30998	0.762	0.492
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	0.084148	0.075884	0.47265	0.536	0.273
startle / PPI	corrected average startle response to full pulse (120 dB) minus average baseline movement during background noise	44.927	23.946	1.0591	0.212	0.0665
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 74dB sound pressure level	41.527	23.487	0.95004	0.250	0.0831
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 78dB sound pressure level	22.679	21.280	0.67493	0.507	0.292
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 82dB sound pressure level	3.2498	17.941	0.28035	0.926	0.857
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	0.00051906	0.079170	0.038541	0.999	0.995
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	0.049101	0.072394	0.29586	0.771	0.501
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	0.077251	0.080383	0.38804	0.604	0.341
startle / PPI	corrected maximum startle response to full pulse (120 dB) minus maximum baseline movement during background noise	144.02	90.197	0.96110	0.308	0.117
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 74dB sound pressure level	122.20	85.305	0.81555	0.373	0.158
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 78dB sound pressure level	62.076	80.884	0.53359	0.646	0.446
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 82dB sound pressure level	5.5149	67.734	0.23977	0.962	0.935
startle / PPI	maximum baseline movement during background noise	-0.13605	1.7012	0.097533	0.984	0.937
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	0.51961	7.3892	0.10739	1.00	0.944
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	5.7743	6.8496	0.43740	0.725	0.403
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	6.6784	7.3012	0.49837	0.654	0.365
startle / PPI	maximum startle response to full pulse (120 dB)	143.74	89.747	0.97228	0.306	0.116
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	120.58	84.717	0.80776	0.376	0.161
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	60.770	80.477	0.53359	0.656	0.454
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	12.119	66.548	0.27453	0.922	0.856
startle / PPI	maximum startle response to pre-pulse, 74dB sound pressure level	-1.8000	1.7482	-0.47315	0.766	0.308
startle / PPI	maximum startle response to pre-pulse, 78dB sound pressure level	-2.1233	3.0068	-0.58271	0.849	0.483
startle / PPI	maximum startle response to pre-pulse, 82dB sound pressure level	6.7167	4.3794	0.93259	0.507	0.131

MULTIPLE (CATEGORICAL) TRAIT PROFILE PLOT — Early Adult Phenotyping study (EAP)

In this plot, data points are the computed genotype effect % vs. C57BL/6NJ controls, for all measured categorical phenotypes in JaxKOMP-EAP

Dimensions Width: × Height: px

Plot Options Group by Procedure

Significance Threshold p-Value Threshold

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Procedure	JaxKOMP-EAP Trait	Trait Effect	P-value

eye morphology	anterior chamber depth	1.0 %	1.0
eye morphology	bulging eye	1.0 %	1.00
eye morphology	cornea	3.0 %	1.00
eye morphology	cornea opacity	3.0 %	1.00
eye morphology	cornea vascularization	2.0 %	1.00
eye morphology	corneal deposits	1.0 %	1.00
eye morphology	corneal mineralization	1.0 %	1.0
eye morphology	corneal scleralization	2.0 %	1.00
eye morphology	corneal ulcer	1.0 %	1.0
eye morphology	eye closure	1.0 %	1.00
eye morphology	eye hemorrhage or blood presence	1.0 %	1.00
eye morphology	eyelid morphology	1.0 %	1.00
eye morphology	eyes (present, absent)	0.0 %	1.00
eye morphology	fusion between cornea and lens	3.0 %	1.00
eye morphology	iris pigmentation	2.0 %	1.00
eye morphology	iris transillumination	1.0 %	1.00
eye morphology	irispupil	6.0 %	0.372
eye morphology	lacrimation	3.0 %	1.0
eye morphology	lens	9.0 %	1.00
eye morphology	lens opacity	6.0 %	0.386
eye morphology	narrow eye opening	1.0 %	1.00
eye morphology	optic disc	7.0 %	0.105
eye morphology	persistence of hyaloid vascular system	6.0 %	0.316
eye morphology	pupil dilation	2.0 %	1.00
eye morphology	pupil light response	84.0 %	8.48e-24
eye morphology	pupil position	4.0 %	1.00
eye morphology	pupil shape	3.0 %	1.00
eye morphology	retina	27.0 %	0.0231
eye morphology	retinal blood vessels	3.0 %	1.00
eye morphology	retinal blood vessels pattern	4.0 %	1.00
eye morphology	retinal blood vessels structure	3.0 %	1.00
eye morphology	retinal pigmentation	13.0 %	0.247
eye morphology	retinal structure	3.0 %	1.00
eye morphology	synechia	3.0 %	1.00
eye morphology	vitreous	3.0 %	1.00
SHIRPA	activity body position	1.0 %	1.00
SHIRPA	aggression	1.0 %	1.0
SHIRPA	body length	0.0 %	1.00
SHIRPA	body position	0.0 %	1.0
SHIRPA	body thickness	0.0 %	1.0
SHIRPA	coat color abdomen	4.0 %	1.0
SHIRPA	coat color back	0.0 %	1.00
SHIRPA	coat color head	0.0 %	1.0
SHIRPA	coat color pattern abdomen	1.0 %	1.0
SHIRPA	coat color pattern back	0.0 %	1.0
SHIRPA	coat color pattern head	0.0 %	1.00
SHIRPA	coat hair abdomen texture appearance	2.0 %	1.0
SHIRPA	coat hair back texture appearance	0.0 %	1.0
SHIRPA	coat hair distribution abdomen	1.0 %	1.00
SHIRPA	coat hair distribution back	0.0 %	1.0
SHIRPA	coat hair distribution head	1.0 %	1.0
SHIRPA	coat hair head texture appearance	0.0 %	1.0
SHIRPA	contact righting	5.0 %	1.00
SHIRPA	ear morphology	0.0 %	1.0
SHIRPA	fat distribution	0.0 %	1.00
SHIRPA	forelimb digit number	0.0 %	1.00
SHIRPA	forelimb digit position	0.0 %	1.0
SHIRPA	forelimb digit shape	0.0 %	1.0
SHIRPA	forelimb digit size	0.0 %	1.0
SHIRPA	forelimb footpads	0.0 %	1.0
SHIRPA	forelimb nail length	0.0 %	1.0
SHIRPA	forelimb nail number	0.0 %	1.0
SHIRPA	forelimb nail position	0.0 %	1.0
SHIRPA	forelimb nail shape	0.0 %	1.0
SHIRPA	forelimbs position	0.0 %	1.0
SHIRPA	forelimbs shape	0.0 %	1.0
SHIRPA	forelimbs size	0.0 %	1.0
SHIRPA	forepaw position	0.0 %	1.0
SHIRPA	forepaw shape	0.0 %	1.0
SHIRPA	forepaw size	0.0 %	1.0
SHIRPA	gait (fluidity)	0.0 %	1.00
SHIRPA	genitalia morphology	0.0 %	1.00
SHIRPA	genitalia presence	0.0 %	1.0
SHIRPA	genitalia size	0.0 %	1.0
SHIRPA	head bobbing	0.0 %	1.0
SHIRPA	head morphology	0.0 %	1.0
SHIRPA	head size	0.0 %	1.00
SHIRPA	hindlimb digit number	0.0 %	1.00
SHIRPA	hindlimb digit position	0.0 %	1.0
SHIRPA	hindlimb digit shape	0.0 %	1.0
SHIRPA	hindlimb digit size	0.0 %	1.00
SHIRPA	hindlimb nail length	0.0 %	1.00
SHIRPA	hindlimb nail number	0.0 %	1.00
SHIRPA	hindlimb nail position	0.0 %	1.0
SHIRPA	hindlimb nail shape	0.0 %	1.0
SHIRPA	hindlimbs footpads	0.0 %	1.0
SHIRPA	hindlimbs position	0.0 %	1.0
SHIRPA	hindlimbs shape	0.0 %	1.0
SHIRPA	hindlimbs size	0.0 %	1.0
SHIRPA	hindpaw position	0.0 %	1.0
SHIRPA	hindpaw shape	0.0 %	1.0
SHIRPA	hindpaw size	0.0 %	1.0
SHIRPA	limb grasp	5.0 %	0.327
SHIRPA	lower lip morphology	0.0 %	1.0
SHIRPA	lower teeth appearance	0.0 %	1.00
SHIRPA	mouth morphology	0.0 %	1.00
SHIRPA	salivation	0.0 %	1.0
SHIRPA	skin color back paws	0.0 %	1.0
SHIRPA	skin color ear	0.0 %	1.0
SHIRPA	skin color front paws	0.0 %	1.0
SHIRPA	skin color snout	0.0 %	1.0
SHIRPA	skin color tail	0.0 %	1.0
SHIRPA	skin color whole body	0.0 %	1.0
SHIRPA	skin texture back paw	0.0 %	1.0
SHIRPA	skin texture ear	0.0 %	1.0
SHIRPA	skin texture front paws	0.0 %	1.0
SHIRPA	skin texture snout	0.0 %	1.0
SHIRPA	skin texture tail	0.0 %	1.0
SHIRPA	skin texture whole body	0.0 %	1.00
SHIRPA	snout size	0.0 %	1.0
SHIRPA	startle response	0.0 %	1.00
SHIRPA	tail curvature	0.0 %	1.0
SHIRPA	tail elevation	5.0 %	0.202
SHIRPA	tail length	0.0 %	1.00
SHIRPA	tail morphology	0.0 %	1.00
SHIRPA	tail presence	0.0 %	1.0
SHIRPA	tail shape	0.0 %	1.00
SHIRPA	tail thickness	0.0 %	1.0
SHIRPA	teeth presence	0.0 %	1.00
SHIRPA	transfer arousal	1.0 %	1.0
SHIRPA	tremor	0.0 %	1.00
SHIRPA	trunk curl	0.0 %	1.0
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	0.0 %	1.00
SHIRPA	upper lip morphology	0.0 %	1.0
SHIRPA	upper teeth appearance	0.0 %	1.00
SHIRPA	vibrissae appearance	1.0 %	1.0
SHIRPA	vibrissae presence	2.0 %	1.0
SHIRPA	vocalization	2.0 %	1.00

GENOTYPE CORRELATION PLOT

Correlate Enpp5^{tm1b(KOMP)Mbp}/2J -/- with genotype: