MPD: JaxKOMP-EAP genotype: Med20<sup>em1(IMPC)J</sup> -/+

JaxKOMP-EAP effect sizes: Med20^em1(IMPC)J -/+ Gene Med20

MULTIPLE (NUMERIC) TRAIT PROFILE PLOT — Early Adult Phenotyping study (EAP)

Procedure	JaxKOMP-EAP Trait	Trait Effect	Trait Effect SE	Trait Effect RankZ	Adjusted p-value	Unadjusted p-value
body composition	body length	-0.012392	0.055583	0.044653	0.930	0.825
body composition	body weight (at time of DXA)	0.10504	0.53535	0.19152	0.933	0.845
body composition	bone area, whole body scan, head excluded	0.060656	0.14232	0.43223	0.844	0.672
body composition	bone mineral content of whole body scan, head excluded	-0.0014766	0.010462	0.046436	0.957	0.888
body composition	bone mineral content to body weight ratio	0.00016961	0.00043568	0.38473	0.851	0.699
body composition	bone mineral density of whole body scan, head excluded	-0.00026156	0.00052683	-0.24349	0.814	0.622
body composition	fat tissue mass of whole body scan, head excluded	0.37338	0.34992	0.60906	0.547	0.292
body composition	fat tissue mass to body weight ratio	0.010398	0.013028	0.52565	0.658	0.429
body composition	lean tissue mass of whole body scan, head excluded	-0.70835	0.30458	-1.4422	0.170	0.0246
body composition	lean tissue mass to body weight ratio	-0.016347	0.010757	-0.90977	0.370	0.136
body composition	percent fat, whole body scan, head excluded	1.1019	1.2315	0.58621	0.620	0.376
body composition	ratio of soft-tissue attenuation coefficients	-0.0012290	0.0013698	-0.59253	0.620	0.374
body composition	tissue area	0.010976	0.28871	0.23588	0.995	0.970
body composition	total tissue mass, whole body scan, head excluded	-0.44732	0.25166	-1.3250	0.262	0.0822
ECT	applied stimulus (current), by day, day 2	0.75431	0.22366	1.6073	0.0490	0.00219
ECT	applied stimulus (current), by day, day 3	0.69856	0.25738	1.4853	0.127	0.0127
ECT	behavior following applied stimulus (current), by day, day 1	-0.62309	0.27711	-1.1409	0.238	0.0326
ECT	behavior following applied stimulus (current), by day, day 3	0.39278	0.46483	0.87242	0.826	0.407
ECT	stimulus level (current) required for minimal clonic forebrain seizure (score of 3 or higher)	0.46391	0.15775	1.1108	0.0777	0.00650
EKG	duration of PQ interval	0.24923	0.75533	0.38402	0.939	0.743
EKG	duration of PR interval	0.49962	0.89281	0.58361	0.930	0.579
EKG	duration of QRS interval	0.25363	0.34173	0.56224	0.920	0.462
EKG	duration of QT interval	0.79275	0.92844	0.93365	0.858	0.398
EKG	duration of QTC interval, calculated by dividing QT interval by square root of preceding RR interval	-0.46384	0.80512	-0.44997	0.926	0.567
EKG	duration of RR interval	4.0200	1.5208	2.1629	0.258	0.0113
EKG	duration of ST interval	0.41528	0.75283	0.63455	0.896	0.584
EKG	heart rate coefficient of variation (signal intensity)	1.2982	1.2994	1.1445	0.864	0.323
EKG	heart rate variability, mean of differences between sequential beats; beats per min	6.6955	9.3462	0.85258	0.887	0.478
EKG	heart rate, beats per min	-32.336	11.886	-2.1626	0.199	0.00930
EKG	mean R amplitude, mean amplitude of signal measured from isoelectric line to peak of QRS	0.0070094	0.082186	-0.077717	0.974	0.932
EKG	mean SR amplitude, mean amplitude of signal measured from signal minimum line to peak of QRS	0.038800	0.11892	0.12434	0.911	0.746
EKG	number of signals	7.3583	5.3822	1.3162	0.706	0.179
EKG	proportion of number pairs of successive beat-to-beat intervals that exceed 50 ms	10.776	5.5441	1.9047	0.758	0.0583
EKG	QT dispersion, measured as inter-lead variability of QT intervals	12.734	4.4781	2.5347	0.765	0.00674
EKG	QTc dispersion, calculated as rate-corrected QT dispersion	11.685	4.8118	2.2068	0.654	0.0193
EKG	root mean square of successive differences of neighboring RR intervals	4.6972	3.0330	1.9345	0.843	0.129
electroretinography	a-wave amplitude of rod photoreceptors, left	-31.3	18.485	-1.7599	0.579	0.151
electroretinography	a-wave amplitude of rod photoreceptors, right	-1.4250	10.123	-0.68326	0.969	0.894
electroretinography	b-wave amplitude of cone photoreceptors, left	19.4	12.166	1.3707	0.717	0.172
electroretinography	b-wave amplitude of cone photoreceptors, right	14.925	8.3750	1.2752	0.576	0.135
electroretinography	b-wave amplitude of rod photoreceptors, left	80.025	46.765	1.8314	0.586	0.148
electroretinography	b-wave amplitude of rod photoreceptors, right	14.075	47.318	0.74198	0.920	0.778
electroretinography	b-wave implicit time of rod photoreceptors (interval from onset of stimulus to peak of the wave), left	0.25000	0.98107	0.022184	0.959	0.809
electroretinography	b-wave implicit time of rod photoreceptors (interval from onset of stimulus to peak of the wave), right	-0.50000	1.0488	-0.61788	0.839	0.654
electroretinography	rod a wave implicit time, left	2.0	0.94868	1.7416	0.442	0.0888
electroretinography	rod a wave implicit time, right	1.75	0.81394	1.4900	0.399	0.0842
electroretinography	rod b wave implicit time, left	1.2820	1.1557	0.38104	0.800	0.329
electroretinography	rod b wave implicit time, right	0.75000	1.25	0.15594	0.897	0.575
glucose tolerance test	amount glucose injected	0.79550	1.9478	0.60489	0.899	0.686
glucose tolerance test	plasma glucose, 0min	-1.1390	4.4568	-0.34876	0.904	0.800
glucose tolerance test	plasma glucose, 15min	11.273	17.501	0.44685	0.798	0.524
glucose tolerance test	plasma glucose, 30min	-0.52206	19.172	0.12386	0.992	0.978
glucose tolerance test	plasma glucose, 60min	4.1243	15.103	0.30675	0.916	0.786
glucose tolerance test	plasma glucose, 120min	3.9275	8.8471	0.14464	0.864	0.660
grip strength	body weight (at time of grip strength test)	0.39673	0.41256	0.58946	0.534	0.343
grip strength	forelimb and hindlimb grip strength (mean of trials), average	3.8781	6.9766	0.51410	0.752	0.582
grip strength	forelimb and hindlimb grip strength (mean of trials), average normalized to bw	0.037777	0.35330	0.25245	0.956	0.915
grip strength	forelimb and hindlimb grip strength by trial, trial1	2.0376	8.5839	0.36833	0.931	0.814
grip strength	forelimb and hindlimb grip strength by trial, trial2	12.044	9.0334	1.0020	0.435	0.191
grip strength	forelimb and hindlimb grip strength by trial, trial3	-1.3323	10.296	0.12376	0.958	0.898
grip strength	forelimb grip strength (mean of trials), average	4.8021	3.6240	0.92352	0.445	0.193
grip strength	forelimb grip strength (mean of trials), average normalized to bw	0.20762	0.19842	0.78937	0.580	0.303
grip strength	forelimb grip strength by trial, trial1	0.81886	4.8148	0.36522	0.949	0.866
grip strength	forelimb grip strength by trial, trial2	13.172	5.5829	1.5926	0.180	0.0239
grip strength	forelimb grip strength by trial, trial3	0.95338	5.5878	0.36677	0.944	0.865
heart weight	heart weight, normalized to body weight	0.24572	0.18307	0.40028	0.393	0.186
heart weight	heart weight, weight	4.2036	4.6503	0.18413	0.584	0.371
hematology	basophil differential (percent of total WBC)	-0.063859	0.030643	-0.91679	0.376	0.0430
hematology	calculated hemoglobin (cHGB)	0.14796	0.14364	0.17471	0.584	0.309
hematology	eosinophil differential (percent of total WBC)	0.17690	0.23505	0.57999	0.800	0.456
hematology	hematocrit (HCT)	1.0030	0.42633	0.79164	0.169	0.0232
hematology	hemoglobin concentration distribution width (HDW)	-0.042165	0.019079	-1.1478	0.222	0.0324
hematology	large unstained cells (percent of total WBC)	-0.19393	0.079878	-1.2037	0.204	0.0193
hematology	lymphocyte differential (percent of total WBC)	1.5673	1.4858	0.54363	0.555	0.297
hematology	mean corpuscular hemoglobin (CHr)	0.066304	0.057270	0.55140	0.488	0.253
hematology	mean platelet volume (MPV)	0.050150	0.042407	0.16609	0.463	0.243
hematology	mean RBC corpuscular hemoglobin (MCH)	0.13794	0.068125	0.50590	0.291	0.0490
hematology	mean RBC corpuscular hemoglobin concentration (MCHC)	-0.028294	0.13707	-0.049331	0.946	0.837
hematology	mean RBC corpuscular volume (MCV)	0.57274	0.21461	0.97326	0.0612	0.0106
hematology	measured hemoglobin (mHGB)	0.33839	0.15958	0.65445	0.237	0.0396
hematology	monocyte differential (percent of total WBC)	-0.21168	0.23736	-0.50288	0.711	0.377
hematology	neutrophil differential (percent of total WBC)	-1.3203	1.2239	-0.60488	0.535	0.287
hematology	platelet count (PLT; units per volume x 10³)	-71.696	39.242	-0.87081	0.390	0.0745
hematology	RBC corpuscular distribution width (RDW)	-0.41179	0.17120	-1.4402	0.138	0.0204
hematology	RBC corpuscular hemoglobin concentration mean (CHCM)	-0.29586	0.14276	-0.80980	0.179	0.0441
hematology	red blood cell count (RBC; per volume x 10⁶)	0.11933	0.11051	0.18717	0.560	0.286
hematology	reticulocyte count (Retic; units per volume x 10⁹)	-14.004	15.576	-0.52361	0.739	0.374
hematology	reticulocyte differential (percent of total RBC)	-0.19942	0.16090	-0.66093	0.592	0.222
hematology	white blood cell count (WBC; units per volume x 10³)	-2.3374	0.66815	-1.3443	0.0130	0.00108
holeboard	number of hole pokes by individual hole number, 20 min test, 1	1.2351	0.84025	1.1329	0.645	0.149
holeboard	number of hole pokes by individual hole number, 20 min test, 2	-0.83534	0.53543	-1.1927	0.670	0.126
holeboard	number of hole pokes by individual hole number, 20 min test, 3	-0.37740	0.56415	-0.56256	0.879	0.507
holeboard	number of hole pokes by individual hole number, 20 min test, 4	1.8360	0.89354	1.6942	0.434	0.0456
holeboard	number of hole pokes by individual hole number, 20 min test, 5	0.23798	0.41508	0.50801	0.897	0.569
holeboard	number of hole pokes by individual hole number, 20 min test, 6	-0.46514	0.30273	-1.3153	0.736	0.131
holeboard	number of hole pokes by individual hole number, 20 min test, 7	0.10577	0.27821	0.29583	0.971	0.706
holeboard	number of hole pokes by individual hole number, 20 min test, 8	-0.51683	0.54684	-0.76019	0.807	0.350
holeboard	number of hole pokes by individual hole number, 20 min test, 9	-0.88582	0.49089	-1.4268	0.504	0.0777
holeboard	number of hole pokes by individual hole number, 20 min test, 10	0.76803	0.58795	1.7076	0.748	0.198
holeboard	number of hole pokes by individual hole number, 20 min test, 11	0.19712	0.30121	0.50934	0.885	0.516
holeboard	number of hole pokes by individual hole number, 20 min test, 12	-0.076299	0.49725	-0.011808	0.971	0.879
holeboard	number of hole pokes by individual hole number, 20 min test, 13	-0.23317	0.73233	-0.14899	0.932	0.752
holeboard	number of hole pokes by individual hole number, 20 min test, 14	-0.65986	0.44217	-0.96116	0.574	0.142
holeboard	number of hole pokes by individual hole number, 20 min test, 15	0.29808	0.43234	0.53177	0.852	0.494
holeboard	number of hole pokes by individual hole number, 20 min test, 16	-0.62749	0.99703	-0.49711	0.844	0.532
holeboard	total number of hole pokes, 20 min test	0.18029	5.3715	0.10477	0.982	0.973
light / dark	fecal boli count, 20 min test	-2.2010	0.77028	-2.3698	0.185	0.00645
light / dark	latency to enter dark zone, 20 min test	7.7215	31.477	0.048692	0.954	0.807
light / dark	number of transitions between light and dark zones, 20 min test	-3.3677	6.9634	-0.23746	0.842	0.631
light / dark	percentage of total time in dark zone, 20 min test	-1.4114	3.8201	-0.13425	0.901	0.714
light / dark	percentage of total time in light zone, 20 min test	1.4114	3.8201	0.13152	0.903	0.714
light / dark	time mobile in dark zone, 20 min test	-16.499	13.340	-1.0625	0.520	0.223
light / dark	time mobile in light zone, 20 min test	-0.0085862	13.217	-0.23885	0.999	0.999
light / dark	time spent in dark zone, 20 min test	-15.415	48.466	-0.010816	0.924	0.752
light / dark	time spent in light zone, 20 min test	15.415	48.466	0.010816	0.924	0.752
open field	average speed in center of arena, 20 min test	0.29996	0.38536	0.45045	0.753	0.440
open field	average speed in periphery of arena, 20 min test	-0.025487	0.13598	-0.62108	0.921	0.852
open field	distance traveled habituation ratio, 20 min test	14.901	7.0604	1.2051	0.250	0.0403
open field	distance traveled in center of arena, 20 min test	97.566	76.276	0.29349	0.459	0.207
open field	distance traveled in periphery of arena, 20 min test	-53.506	143.53	-0.64404	0.848	0.711
open field	distance traveled slope, 20 min test	14.959	6.8214	1.3023	0.233	0.0334
open field	distance traveled, 20 min test, 1st 5min	-67.285	68.106	-0.86364	0.570	0.328
open field	distance traveled, 20 min test, 2nd 5min	-24.152	56.664	-0.77534	0.834	0.672
open field	distance traveled, 20 min test, 3rd 5min	81.758	43.790	0.45492	0.235	0.0683
open field	distance traveled, 20 min test, 4th 5min	55.821	50.775	0.15162	0.521	0.277
open field	number of clockwise revolution episodes, 20 min test	-2.1131	1.5109	-1.6730	0.517	0.169
open field	number of counter-clockwise revolution episodes, 20 min test	4.0356	1.1996	1.5594	0.0342	0.00156
open field	number of fecal boli, 20 min test	-1.2024	1.0813	-0.70431	0.608	0.272
open field	number of rears in 5 min bins, 20 min test, 1st 5min	-6.4703	1.8116	-1.8886	0.0208	0.000859
open field	number of rears in 5 min bins, 20 min test, 2nd 5min	1.2945	2.1469	-0.039617	0.771	0.549
open field	number of rears in 5 min bins, 20 min test, 3rd 5min	3.8221	2.1815	0.58724	0.295	0.0864
open field	number of rears in 5 min bins, 20 min test, 4th 5min	4.9547	2.9243	0.76451	0.329	0.0971
open field	percentage of total time in center of arena, 20 min test	1.4050	2.8589	0.11775	0.852	0.625
open field	percentage of total time in center of arena, slope, 20 min test	0.39422	1.5436	0.33581	0.955	0.800
open field	percentage of total time in center, habituation ratio, 20 min test	0.69094	1.5953	0.49702	0.901	0.667
open field	percentage of total time in corners of arena, 20 min test	-5.7052	3.5775	-0.77172	0.415	0.118
open field	percentage of total time in corners, habituation ratio, 20 min test	-1.3987	1.8245	-0.94236	0.856	0.447
open field	percentage of total time in corners, slope, 20 min test	-1.6063	1.7861	-1.0458	0.816	0.373
open field	permanence time in center of arena, 20 min test	16.856	34.307	0.11775	0.853	0.626
open field	permanence time in corners of arena, 20 min test	-68.461	42.929	-0.77172	0.415	0.118
open field	permanence time in periphery of arena, 20 min test	-16.826	34.299	-0.11775	0.853	0.626
open field	total distance traveled, 20 min test	72.550	185.51	-0.26974	0.842	0.698
open field	total number of rears, 20 min test	2.5760	7.7824	-0.15298	0.871	0.742
open field	whole arena average speed, 20 min test	0.061046	0.15451	-0.26974	0.839	0.695
open field	whole arena resting time, 20 min test	-16.292	18.065	0.075930	0.573	0.372
open field	whole arena time spent mobile, 20 min test	16.335	18.063	0.16930	0.582	0.371
open field	whole arena time spent vertical, 20 min test	-0.96744	6.2525	-0.18840	0.951	0.878
rotarod	learning difference on accelerating rotarod (4-40 rpm/5 min) over 5 trials	24.882	11.388	1.9900	0.582	0.0341
rotarod	learning slope on accelerating rotarod (4-40 rpm/5 min) over 5 trials	7.8848	3.6675	1.9900	0.564	0.0370
rotarod	mean duration on accelerating rotarod (4-40 rpm/5 min) over 5 trials	11.460	8.8542	1.2898	0.544	0.202
rotarod	mean latency to fall off accelerating rotarod (4-40 rpm/ 5 min) over 5 trials	30.085	13.828	1.9900	0.353	0.0349
SHIRPA	locomotor activity (number of squares in the arena the mouse moves into with all four paws in first 30 s of test)	1.8873	1.8111	0.98283	0.612	0.304
startle / PPI	average baseline movement during background noise	-0.52055	1.2280	-0.31404	0.933	0.674
startle / PPI	average of each corrected maximum percent pre-pulse inhibition value	-0.066965	0.069717	-0.71416	0.686	0.344
startle / PPI	average of each corrected percent pre-pulse inhibition value	-0.064642	0.069149	-0.73887	0.693	0.356
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	5.4564	10.485	0.64877	0.931	0.606
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-9.1470	6.5282	-0.93910	0.530	0.170
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-15.684	5.1933	-1.5378	0.0776	0.00477
startle / PPI	average startle response to full pulse (120 dB)	1.9749	19.778	0.25566	0.967	0.921
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	10.938	16.378	0.42510	0.724	0.509
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	14.428	12.472	0.51270	0.474	0.255
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	21.772	12.261	0.71597	0.260	0.0847
startle / PPI	average startle response to pre-pulse, 74dB sound pressure level	0.12028	1.3776	0.17534	0.987	0.931
startle / PPI	average startle response to pre-pulse, 78dB sound pressure level	-0.78158	1.5567	-0.52714	0.926	0.619
startle / PPI	average startle response to pre-pulse, 82dB sound pressure level	-2.9712	2.1727	-1.5952	0.626	0.181
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	0.080544	0.11443	0.81165	0.903	0.486
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-0.10921	0.080044	-0.99427	0.526	0.181
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-0.16875	0.062063	-1.4479	0.0879	0.0102
startle / PPI	corrected average startle response to full pulse (120 dB) minus average baseline movement during background noise	2.3466	20.297	0.26581	0.961	0.909
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 74dB sound pressure level	10.818	16.594	0.41897	0.725	0.519
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 78dB sound pressure level	15.238	13.011	0.52553	0.467	0.250
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 82dB sound pressure level	24.149	12.280	0.76952	0.195	0.0574
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	0.083711	0.12102	0.76388	0.916	0.494
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-0.11401	0.082513	-0.96966	0.517	0.176
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-0.18907	0.063219	-1.5285	0.0566	0.00515
startle / PPI	corrected maximum startle response to full pulse (120 dB) minus maximum baseline movement during background noise	38.550	71.413	0.41439	0.802	0.593
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 74dB sound pressure level	65.148	63.964	0.51910	0.553	0.316
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 78dB sound pressure level	80.750	48.751	0.63157	0.286	0.107
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 82dB sound pressure level	105.35	45.151	0.86542	0.118	0.0257
startle / PPI	maximum baseline movement during background noise	-2.0337	2.1690	-0.54981	0.801	0.355
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	5.7235	11.243	0.61117	0.938	0.614
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-9.3389	6.6900	-0.89640	0.528	0.172
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-16.299	5.6908	-1.5470	0.0878	0.00712
startle / PPI	maximum startle response to full pulse (120 dB)	36.552	70.778	0.39917	0.812	0.609
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	66.137	63.688	0.52392	0.542	0.306
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	77.337	47.343	0.61117	0.294	0.112
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	95.709	44.624	0.80776	0.153	0.0392
startle / PPI	maximum startle response to pre-pulse, 74dB sound pressure level	0.98899	3.0840	0.44822	0.950	0.750
startle / PPI	maximum startle response to pre-pulse, 78dB sound pressure level	-3.3306	5.3757	-0.91541	0.877	0.540
startle / PPI	maximum startle response to pre-pulse, 82dB sound pressure level	-10.010	6.1861	-1.9767	0.493	0.115
urinalysis	albumin-creatinine ratio (urine ACR)	-1.5115	1.2201	-1.1523	0.433	0.222
urinalysis	creatinine (urine CREA)	-6.2641	3.6550	-0.46371	0.274	0.0938
urinalysis	glucose (urine GLU)	-3.6967	2.0552	-1.2419	0.400	0.0791
urinalysis	magnesium level (urine Mg)	-0.34188	0.21208	-2.0619	0.379	0.115
urinalysis	microalbumin (urine MA), calculated	-0.17674	0.097206	-1.0329	0.321	0.0760

MULTIPLE (CATEGORICAL) TRAIT PROFILE PLOT — Early Adult Phenotyping study (EAP)

Procedure	JaxKOMP-EAP Trait	Trait Effect	P-value
electroretinography	blind eyes, left	0.0 %	1.0
electroretinography	blind eyes, right	0.0 %	1.0
eye morphology	anterior chamber depth	1.0 %	1.0
eye morphology	bulging eye	1.0 %	1.00
eye morphology	cornea	3.0 %	1.00
eye morphology	cornea opacity	4.0 %	0.428
eye morphology	cornea vascularization	2.0 %	1.00
eye morphology	corneal deposits	1.0 %	1.00
eye morphology	corneal mineralization	1.0 %	1.00
eye morphology	corneal scleralization	2.0 %	1.00
eye morphology	corneal ulcer	1.0 %	1.00
eye morphology	eye closure	1.0 %	1.0
eye morphology	eye hemorrhage or blood presence	1.0 %	1.00
eye morphology	eyelid morphology	1.0 %	1.0
eye morphology	eyes (present, absent)	0.0 %	1.0
eye morphology	fusion between cornea and lens	3.0 %	1.00
eye morphology	iris pigmentation	2.0 %	1.00
eye morphology	iris transillumination	1.0 %	1.00
eye morphology	irispupil	5.0 %	0.435
eye morphology	lacrimation	3.0 %	1.00
eye morphology	lens	41.0 %	0.000136
eye morphology	lens opacity	7.0 %	1.00
eye morphology	narrow eye opening	6.0 %	0.144
eye morphology	optic disc	3.0 %	1.00
eye morphology	persistence of hyaloid vascular system	5.0 %	0.400
eye morphology	pupil dilation	2.0 %	1.0
eye morphology	pupil light response	2.0 %	1.00
eye morphology	pupil position	5.0 %	0.461
eye morphology	pupil shape	5.0 %	0.342
eye morphology	retina	7.0 %	0.801
eye morphology	retinal blood vessels	6.0 %	0.0329
eye morphology	retinal blood vessels pattern	4.0 %	1.00
eye morphology	retinal blood vessels structure	3.0 %	1.00
eye morphology	retinal pigmentation	31.0 %	0.00715
eye morphology	retinal structure	3.0 %	1.00
eye morphology	synechia	3.0 %	1.00
eye morphology	vitreous	3.0 %	1.00
rotarod	outcome of accelerating rotarod (4-40 rpm/ 5 min) over 5 trials	0.0 %	1.0
rotarod	trial number	0.0 %	1.0
SHIRPA	activity body position	1.0 %	1.00
SHIRPA	aggression	1.0 %	1.0
SHIRPA	body length	0.0 %	1.00
SHIRPA	body position	0.0 %	1.0
SHIRPA	body thickness	0.0 %	1.0
SHIRPA	coat color abdomen	4.0 %	1.0
SHIRPA	coat color back	0.0 %	1.00
SHIRPA	coat color head	0.0 %	1.0
SHIRPA	coat color pattern abdomen	1.0 %	1.0
SHIRPA	coat color pattern back	0.0 %	1.0
SHIRPA	coat color pattern head	0.0 %	1.00
SHIRPA	coat hair abdomen texture appearance	2.0 %	1.0
SHIRPA	coat hair back texture appearance	0.0 %	1.0
SHIRPA	coat hair distribution abdomen	1.0 %	1.00
SHIRPA	coat hair distribution back	0.0 %	1.0
SHIRPA	coat hair distribution head	1.0 %	1.0
SHIRPA	coat hair head texture appearance	0.0 %	1.0
SHIRPA	contact righting	5.0 %	1.00
SHIRPA	ear morphology	0.0 %	1.0
SHIRPA	fat distribution	0.0 %	1.00
SHIRPA	forelimb digit number	0.0 %	1.00
SHIRPA	forelimb digit position	0.0 %	1.0
SHIRPA	forelimb digit shape	0.0 %	1.0
SHIRPA	forelimb digit size	0.0 %	1.0
SHIRPA	forelimb footpads	0.0 %	1.0
SHIRPA	forelimb nail length	0.0 %	1.0
SHIRPA	forelimb nail number	0.0 %	1.0
SHIRPA	forelimb nail position	0.0 %	1.0
SHIRPA	forelimb nail shape	0.0 %	1.0
SHIRPA	forelimbs position	0.0 %	1.0
SHIRPA	forelimbs shape	0.0 %	1.0
SHIRPA	forelimbs size	0.0 %	1.0
SHIRPA	forepaw position	0.0 %	1.0
SHIRPA	forepaw shape	0.0 %	1.0
SHIRPA	forepaw size	0.0 %	1.0
SHIRPA	gait (fluidity)	0.0 %	1.00
SHIRPA	genitalia morphology	0.0 %	1.00
SHIRPA	genitalia presence	0.0 %	1.0
SHIRPA	genitalia size	0.0 %	1.0
SHIRPA	head bobbing	0.0 %	1.0
SHIRPA	head morphology	0.0 %	1.0
SHIRPA	head size	0.0 %	1.00
SHIRPA	hindlimb digit number	0.0 %	1.00
SHIRPA	hindlimb digit position	0.0 %	1.0
SHIRPA	hindlimb digit shape	0.0 %	1.0
SHIRPA	hindlimb digit size	0.0 %	1.00
SHIRPA	hindlimb nail length	0.0 %	1.00
SHIRPA	hindlimb nail number	0.0 %	1.00
SHIRPA	hindlimb nail position	0.0 %	1.0
SHIRPA	hindlimb nail shape	0.0 %	1.0
SHIRPA	hindlimbs footpads	0.0 %	1.0
SHIRPA	hindlimbs position	0.0 %	1.0
SHIRPA	hindlimbs shape	0.0 %	1.0
SHIRPA	hindlimbs size	0.0 %	1.0
SHIRPA	hindpaw position	0.0 %	1.0
SHIRPA	hindpaw shape	0.0 %	1.0
SHIRPA	hindpaw size	0.0 %	1.0
SHIRPA	limb grasp	5.0 %	0.327
SHIRPA	lower lip morphology	0.0 %	1.0
SHIRPA	lower teeth appearance	0.0 %	1.00
SHIRPA	mouth morphology	0.0 %	1.00
SHIRPA	salivation	0.0 %	1.0
SHIRPA	skin color back paws	0.0 %	1.0
SHIRPA	skin color ear	0.0 %	1.0
SHIRPA	skin color front paws	0.0 %	1.0
SHIRPA	skin color snout	0.0 %	1.0
SHIRPA	skin color tail	0.0 %	1.0
SHIRPA	skin color whole body	0.0 %	1.0
SHIRPA	skin texture back paw	0.0 %	1.0
SHIRPA	skin texture ear	0.0 %	1.0
SHIRPA	skin texture front paws	0.0 %	1.0
SHIRPA	skin texture snout	0.0 %	1.0
SHIRPA	skin texture tail	0.0 %	1.0
SHIRPA	skin texture whole body	0.0 %	1.00
SHIRPA	snout size	0.0 %	1.0
SHIRPA	startle response	0.0 %	1.00
SHIRPA	tail curvature	0.0 %	1.0
SHIRPA	tail elevation	1.0 %	1.0
SHIRPA	tail length	0.0 %	1.00
SHIRPA	tail morphology	0.0 %	1.00
SHIRPA	tail presence	0.0 %	1.0
SHIRPA	tail shape	0.0 %	1.00
SHIRPA	tail thickness	0.0 %	1.0
SHIRPA	teeth presence	0.0 %	1.00
SHIRPA	transfer arousal	1.0 %	1.0
SHIRPA	tremor	0.0 %	1.00
SHIRPA	trunk curl	0.0 %	1.0
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	0.0 %	1.00
SHIRPA	upper lip morphology	0.0 %	1.0
SHIRPA	upper teeth appearance	0.0 %	1.00
SHIRPA	vibrissae appearance	1.0 %	1.0
SHIRPA	vibrissae presence	2.0 %	1.0
SHIRPA	vocalization	2.0 %	1.00

GENOTYPE CORRELATION PLOT

Correlate Med20^em1(IMPC)J -/+ with genotype: