MPD: JaxKOMP-EAP genotype: Smg9<sup>em1(IMPC)J</sup> -/+

JaxKOMP-EAP effect sizes: Smg9^em1(IMPC)J -/+ Gene Smg9

MULTIPLE (NUMERIC) TRAIT PROFILE PLOT — Early Adult Phenotyping study (EAP)

Procedure	JaxKOMP-EAP Trait	Trait Effect	Trait Effect SE	Trait Effect RankZ	Adjusted p-value	Unadjusted p-value
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 12 kHz pip	6.3121	1.9267	1.2193	0.277	0.0169
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 18 kHz pip	3.7529	2.4603	0.58993	0.537	0.178
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 24 kHz pip	1.8750	3.3190	0.18185	0.843	0.593
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 30 kHz pip	1.8993	5.0652	0.27250	0.887	0.721
body composition	body length	0.16229	0.045105	1.8476	0.0206	0.00107
body composition	body weight (at time of DXA)	1.2230	0.62582	1.1441	0.187	0.0592
body composition	bone area, whole body scan, head excluded	0.092889	0.12256	0.58297	0.704	0.454
body composition	bone mineral content of whole body scan, head excluded	0.0063633	0.0088142	0.49919	0.727	0.476
body composition	bone mineral content to body weight ratio	-0.000019612	0.00038554	0.12318	0.983	0.960
body composition	bone mineral density of whole body scan, head excluded	0.00015749	0.00039374	0.20426	0.856	0.692
body composition	fat tissue mass of whole body scan, head excluded	-0.074432	0.23193	-0.12869	0.876	0.750
body composition	fat tissue mass to body weight ratio	-0.0033070	0.0080802	-0.092972	0.844	0.685
body composition	lean tissue mass of whole body scan, head excluded	0.34842	0.24278	0.57651	0.457	0.161
body composition	lean tissue mass to body weight ratio	0.0031028	0.0075879	0.11019	0.851	0.685
body composition	percent fat, whole body scan, head excluded	-0.31318	0.78046	-0.086118	0.852	0.691
body composition	ratio of soft-tissue attenuation coefficients	0.00035423	0.00086873	0.093175	0.849	0.686
body composition	tissue area	0.16474	0.16210	0.71186	0.624	0.317
body composition	total tissue mass, whole body scan, head excluded	0.24388	0.16429	0.32079	0.375	0.147
clinical blood chemistry	alanine transaminase (plasma ALT)	14.503	14.056	0.96028	0.673	0.311
clinical blood chemistry	albumin (plasma Alb)	-0.65924	0.33039	-0.82467	0.296	0.0562
clinical blood chemistry	alkaline phosphatase (plasma ALP)	-0.12905	3.7007	-0.54516	0.986	0.972
clinical blood chemistry	aspartate transaminase (plasma AST)	5.8998	28.201	0.29190	0.952	0.836
clinical blood chemistry	aspartate transaminase to alanine transaminase ratio (plasma AST:ALT)	-0.11079	0.30921	-0.33999	0.917	0.723
clinical blood chemistry	blood urea nitrogen (BUN)	1.5951	1.0895	0.61667	0.389	0.155
clinical blood chemistry	calcium (plasma Ca)	-0.14884	0.078742	-0.73789	0.228	0.0695
clinical blood chemistry	creatinine (plasma)	-0.0097705	0.019216	-0.12185	0.793	0.616
clinical blood chemistry	glucose (plasma GLU, no fast)	-47.178	10.002	-1.2963	0.00163	0.0000710
clinical blood chemistry	HDL cholesterol (plasma HDL)	-0.63605	1.8042	-0.48688	0.897	0.727
clinical blood chemistry	HDL cholesterol to total cholesterol ratio	0.011754	0.0091472	0.49410	0.546	0.210
clinical blood chemistry	phosphorus (plasma phosphate)	0.38881	0.26803	0.53374	0.419	0.158
clinical blood chemistry	total bilirubin (plasma TBIL)	0.00011006	0.011392	0.012775	0.999	0.992
clinical blood chemistry	total cholesterol (plasma CHOL, no fast)	-1.6296	2.0504	-0.52587	0.729	0.434
clinical blood chemistry	total protein (plasma TP)	-0.16858	0.46515	-0.19101	0.869	0.720
clinical blood chemistry	triglyceride (plasma TG, no fast)	-2.7703	6.3122	0.077336	0.845	0.664
EKG	duration of PQ interval	0.29018	0.67449	0.44329	0.939	0.682
EKG	duration of PR interval	0.64866	0.73128	0.76861	0.883	0.409
EKG	duration of QRS interval	0.50179	0.27836	1.3162	0.885	0.122
EKG	duration of QT interval	0.91741	0.69864	1.0316	0.725	0.237
EKG	duration of QTC interval, calculated by dividing QT interval by square root of preceding RR interval	1.1205	0.84638	1.1883	0.790	0.234
EKG	duration of RR interval	-0.49130	1.2719	0.014105	0.901	0.713
EKG	duration of ST interval	0.43437	0.70461	0.66441	0.884	0.560
EKG	heart rate coefficient of variation (signal intensity)	0.63348	0.93069	0.60283	0.891	0.521
EKG	heart rate variability, mean of differences between sequential beats; beats per min	4.3040	6.6364	0.58361	0.917	0.541
EKG	heart rate, beats per min	6.2976	10.766	0.11013	0.832	0.580
EKG	mean R amplitude, mean amplitude of signal measured from isoelectric line to peak of QRS	0.16953	0.17506	1.1919	0.722	0.370
EKG	mean SR amplitude, mean amplitude of signal measured from signal minimum line to peak of QRS	0.24460	0.22705	1.3158	0.669	0.323
EKG	number of signals	-4.1172	3.8707	-0.85548	0.816	0.328
EKG	proportion of number pairs of successive beat-to-beat intervals that exceed 50 ms	3.9155	3.9479	0.81127	0.846	0.360
EKG	QT dispersion, measured as inter-lead variability of QT intervals	-1.1525	3.5614	-0.31123	0.971	0.757
EKG	QTc dispersion, calculated as rate-corrected QT dispersion	-2.4749	3.8316	-0.68464	0.932	0.542
EKG	root mean square of successive differences of neighboring RR intervals	0.81067	1.9055	0.55752	0.945	0.685
glucose tolerance test	amount glucose injected	-0.38492	1.9355	0.26074	0.951	0.844
glucose tolerance test	plasma glucose, 0min	-8.3732	5.2062	-0.98362	0.287	0.117
glucose tolerance test	plasma glucose, 15min	-5.9007	28.434	-0.060437	0.942	0.837
glucose tolerance test	plasma glucose, 30min	-46.643	21.580	-1.2349	0.224	0.0376
glucose tolerance test	plasma glucose, 60min	-39.679	19.658	-1.4833	0.263	0.0513
glucose tolerance test	plasma glucose, 120min	-2.0440	9.7601	-0.27667	0.937	0.835
grip strength	body weight (at time of grip strength test)	2.6710	0.59451	2.3551	0.00393	0.000321
grip strength	forelimb and hindlimb grip strength (mean of trials), average	-21.250	13.070	-1.1929	0.292	0.124
grip strength	forelimb and hindlimb grip strength (mean of trials), average normalized to bw	-0.99638	0.51915	-1.2139	0.211	0.0719
grip strength	forelimb and hindlimb grip strength by trial, trial1	-37.688	18.941	-2.0138	0.259	0.0640
grip strength	forelimb and hindlimb grip strength by trial, trial2	-8.0601	10.154	-0.25545	0.682	0.439
grip strength	forelimb and hindlimb grip strength by trial, trial3	-24.872	20.154	-1.3243	0.502	0.235
grip strength	forelimb grip strength (mean of trials), average	3.1079	7.1344	0.69746	0.851	0.669
grip strength	forelimb grip strength (mean of trials), average normalized to bw	-0.59100	0.39226	-1.1782	0.397	0.150
grip strength	forelimb grip strength by trial, trial1	6.1203	7.9589	0.98300	0.775	0.452
grip strength	forelimb grip strength by trial, trial2	-9.5275	13.440	-0.81542	0.782	0.489
grip strength	forelimb grip strength by trial, trial3	2.6265	9.5735	0.54248	0.920	0.787
heart weight	heart weight, normalized to body weight	0.15044	0.12140	0.10220	0.441	0.222
heart weight	heart weight, weight	3.1972	2.8600	0.050695	0.479	0.270
hematology	basophil differential (percent of total WBC)	-0.19964	0.063712	-1.9037	0.161	0.00425
hematology	calculated hemoglobin (cHGB)	0.40425	0.69415	1.0022	0.785	0.565
hematology	eosinophil differential (percent of total WBC)	0.20091	0.21931	0.64096	0.750	0.368
hematology	hematocrit (HCT)	2.0028	2.3501	1.6277	0.661	0.402
hematology	hemoglobin concentration distribution width (HDW)	-0.015088	0.021160	-0.39226	0.737	0.482
hematology	large unstained cells (percent of total WBC)	-0.13979	0.10222	-0.89376	0.530	0.183
hematology	lymphocyte differential (percent of total WBC)	0.86367	1.9631	0.32404	0.822	0.663
hematology	mean corpuscular hemoglobin (CHr)	-0.0069443	0.052140	-0.031113	0.947	0.895
hematology	mean platelet volume (MPV)	-0.053563	0.10338	-0.55471	0.793	0.609
hematology	mean RBC corpuscular hemoglobin (MCH)	0.45588	0.54735	1.4392	0.750	0.412
hematology	mean RBC corpuscular hemoglobin concentration (MCHC)	0.51775	1.1874	1.0098	0.874	0.666
hematology	mean RBC corpuscular volume (MCV)	0.55427	0.26691	0.94511	0.167	0.0475
hematology	measured hemoglobin (mHGB)	0.69496	0.87433	1.5062	0.695	0.434
hematology	monocyte differential (percent of total WBC)	-0.29706	0.30758	-0.74392	0.680	0.343
hematology	neutrophil differential (percent of total WBC)	-0.48140	1.8151	-0.23588	0.891	0.793
hematology	platelet count (PLT; units per volume x 10³)	81.587	75.174	1.0970	0.646	0.287
hematology	RBC corpuscular distribution width (RDW)	0.10147	0.13108	0.34743	0.677	0.446
hematology	RBC corpuscular hemoglobin concentration mean (CHCM)	-0.42599	0.17192	-1.1571	0.107	0.0198
hematology	red blood cell count (RBC; per volume x 10⁶)	0.31692	0.51231	1.0454	0.755	0.541
hematology	reticulocyte count (Retic; units per volume x 10⁹)	6.0549	20.330	0.35846	0.934	0.768
hematology	reticulocyte differential (percent of total RBC)	-0.060101	0.11828	-0.033677	0.845	0.615
hematology	white blood cell count (WBC; units per volume x 10³)	-2.2282	0.52710	-1.2922	0.00496	0.000276
holeboard	number of hole pokes by individual hole number, 20 min test, 1	0.46943	1.2413	0.52731	0.926	0.730
holeboard	number of hole pokes by individual hole number, 20 min test, 2	1.1394	1.1727	1.7307	0.825	0.403
holeboard	number of hole pokes by individual hole number, 20 min test, 3	1.0125	0.69077	1.5441	0.745	0.239
holeboard	number of hole pokes by individual hole number, 20 min test, 4	0.40000	1.2076	0.47373	0.929	0.762
holeboard	number of hole pokes by individual hole number, 20 min test, 5	0.90165	1.2175	1.3819	0.871	0.513
holeboard	number of hole pokes by individual hole number, 20 min test, 6	-0.0035330	0.25877	0.028680	1.00	0.990
holeboard	number of hole pokes by individual hole number, 20 min test, 7	0.26250	0.49150	0.68888	0.958	0.630
holeboard	number of hole pokes by individual hole number, 20 min test, 8	0.47078	0.56094	0.93426	0.867	0.463
holeboard	number of hole pokes by individual hole number, 20 min test, 9	0.10000	0.69282	0.28593	0.987	0.894
holeboard	number of hole pokes by individual hole number, 20 min test, 10	0.38750	0.37590	0.98650	0.861	0.378
holeboard	number of hole pokes by individual hole number, 20 min test, 11	0.012534	0.41343	0.043931	0.994	0.978
holeboard	number of hole pokes by individual hole number, 20 min test, 12	0.93508	0.74860	1.4322	0.738	0.300
holeboard	number of hole pokes by individual hole number, 20 min test, 13	1.0500	1.2296	1.1050	0.794	0.456
holeboard	number of hole pokes by individual hole number, 20 min test, 14	0.56381	1.4015	0.92174	0.915	0.714
holeboard	number of hole pokes by individual hole number, 20 min test, 15	-0.24076	1.3035	-0.28553	0.962	0.865
holeboard	number of hole pokes by individual hole number, 20 min test, 16	0.61581	1.5909	0.57105	0.931	0.725
holeboard	total number of hole pokes, 20 min test	7.5664	9.5089	1.0684	0.724	0.484
light / dark	fecal boli count, 20 min test	-0.97706	0.86900	-1.0988	0.672	0.268
light / dark	latency to enter dark zone, 20 min test	22.753	70.937	0.33611	0.934	0.750
light / dark	number of transitions between light and dark zones, 20 min test	-2.9059	8.4025	-0.17393	0.892	0.731
light / dark	percentage of total time in dark zone, 20 min test	-2.1655	6.5410	-0.25838	0.914	0.742
light / dark	percentage of total time in light zone, 20 min test	2.1655	6.5410	0.25279	0.916	0.742
light / dark	time mobile in dark zone, 20 min test	2.6485	16.431	0.075785	0.950	0.873
light / dark	time mobile in light zone, 20 min test	35.483	13.710	1.5249	0.0986	0.0138
light / dark	time spent in dark zone, 20 min test	-69.901	76.026	-0.83739	0.739	0.364
light / dark	time spent in light zone, 20 min test	69.901	76.026	0.83739	0.739	0.364
open field	average speed in center of arena, 20 min test	-0.47964	0.42825	-0.98290	0.613	0.268
open field	average speed in periphery of arena, 20 min test	0.13864	0.10849	0.059781	0.416	0.207
open field	distance traveled habituation ratio, 20 min test	8.7783	7.9348	0.71335	0.601	0.274
open field	distance traveled in center of arena, 20 min test	259.44	103.36	1.1940	0.0975	0.0154
open field	distance traveled in periphery of arena, 20 min test	-53.850	116.58	-0.64569	0.810	0.646
open field	distance traveled slope, 20 min test	9.3009	7.8801	0.81775	0.575	0.243
open field	distance traveled, 20 min test, 1st 5min	27.312	64.337	-0.10424	0.849	0.673
open field	distance traveled, 20 min test, 2nd 5min	14.900	41.676	-0.33581	0.855	0.722
open field	distance traveled, 20 min test, 3rd 5min	56.888	44.493	0.18703	0.438	0.207
open field	distance traveled, 20 min test, 4th 5min	106.31	48.596	0.67238	0.157	0.0334
open field	number of clockwise revolution episodes, 20 min test	1.9375	1.0337	0.73212	0.328	0.0667
open field	number of counter-clockwise revolution episodes, 20 min test	2.3125	1.4470	0.77172	0.379	0.116
open field	number of fecal boli, 20 min test	0.31359	1.0168	0.49137	0.894	0.759
open field	number of rears in 5 min bins, 20 min test, 1st 5min	-2.5250	2.0846	-0.89289	0.496	0.231
open field	number of rears in 5 min bins, 20 min test, 2nd 5min	0.67500	2.3041	-0.18430	0.896	0.771
open field	number of rears in 5 min bins, 20 min test, 3rd 5min	-0.45947	2.6206	-0.40484	0.935	0.862
open field	number of rears in 5 min bins, 20 min test, 4th 5min	4.7907	2.9893	0.72902	0.358	0.115
open field	percentage of total time in center of arena, 20 min test	8.6743	2.9277	1.6113	0.0860	0.00466
open field	percentage of total time in center of arena, slope, 20 min test	3.0499	1.2380	1.7612	0.331	0.0172
open field	percentage of total time in center, habituation ratio, 20 min test	3.0521	1.2368	1.7487	0.315	0.0171
open field	percentage of total time in corners of arena, 20 min test	-10.571	3.4926	-1.6064	0.0693	0.00390
open field	percentage of total time in corners, habituation ratio, 20 min test	-1.4845	1.7326	-0.98073	0.843	0.396
open field	percentage of total time in corners, slope, 20 min test	-1.4409	1.6995	-0.96564	0.834	0.401
open field	permanence time in center of arena, 20 min test	104.08	35.131	1.6113	0.0860	0.00466
open field	permanence time in corners of arena, 20 min test	-126.86	41.912	-1.6064	0.0693	0.00390
open field	permanence time in periphery of arena, 20 min test	-104.10	35.132	-1.6113	0.0860	0.00465
open field	total distance traveled, 20 min test	205.59	148.71	0.11910	0.369	0.173
open field	total number of rears, 20 min test	3.4790	7.5582	-0.098842	0.819	0.647
open field	whole arena average speed, 20 min test	0.17225	0.12393	0.12316	0.365	0.171
open field	whole arena resting time, 20 min test	-30.264	15.631	-0.29629	0.183	0.0585
open field	whole arena time spent mobile, 20 min test	30.170	15.618	0.54781	0.183	0.0591
open field	whole arena time spent vertical, 20 min test	-0.94625	8.1994	-0.18567	0.964	0.909
SHIRPA	locomotor activity (number of squares in the arena the mouse moves into with all four paws in first 30 s of test)	-2.8319	2.2983	-1.0119	0.551	0.236
startle / PPI	average baseline movement during background noise	-1.1552	1.0100	-0.79809	0.766	0.260
startle / PPI	average of each corrected maximum percent pre-pulse inhibition value	0.015418	0.071609	0.031531	0.933	0.831
startle / PPI	average of each corrected percent pre-pulse inhibition value	0.045067	0.060206	0.36943	0.770	0.459
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-1.0626	7.4271	-0.077841	0.994	0.887
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	4.3391	5.9870	0.38102	0.770	0.473
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	8.7379	5.9879	0.78468	0.429	0.152
startle / PPI	average startle response to full pulse (120 dB)	-6.9750	24.699	0.037139	0.911	0.779
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-23.574	26.253	-0.29788	0.611	0.375
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-20.842	23.025	-0.25277	0.583	0.371
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-18.999	20.325	-0.27890	0.576	0.356
startle / PPI	average startle response to pre-pulse, 74dB sound pressure level	-1.2999	0.89078	-0.88598	0.677	0.152
startle / PPI	average startle response to pre-pulse, 78dB sound pressure level	0.44653	0.90234	0.31993	0.927	0.623
startle / PPI	average startle response to pre-pulse, 82dB sound pressure level	3.0250	1.2722	1.0567	0.266	0.0223
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-0.018641	0.079353	-0.12573	0.970	0.815
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	0.062756	0.064474	0.44256	0.664	0.336
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	0.085660	0.073564	0.48522	0.513	0.251
startle / PPI	corrected average startle response to full pulse (120 dB) minus average baseline movement during background noise	-6.2813	24.842	0.053970	0.918	0.802
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 74dB sound pressure level	-22.765	26.289	-0.27744	0.626	0.392
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 78dB sound pressure level	-21.288	23.185	-0.25856	0.573	0.364
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 82dB sound pressure level	-22.024	20.695	-0.33323	0.508	0.294
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-0.047642	0.085456	-0.38555	0.929	0.580
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	0.078177	0.069841	0.53796	0.622	0.270
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	0.031890	0.11721	0.064533	0.914	0.787
startle / PPI	corrected maximum startle response to full pulse (120 dB) minus maximum baseline movement during background noise	-28.035	88.756	0.020318	0.897	0.754
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 74dB sound pressure level	-107.43	93.732	-0.42356	0.494	0.259
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 78dB sound pressure level	-44.712	90.995	-0.059583	0.770	0.626
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 82dB sound pressure level	-78.567	77.367	-0.30668	0.530	0.316
startle / PPI	maximum baseline movement during background noise	-2.9697	1.9495	-0.82536	0.624	0.136
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-3.8877	8.1996	-0.34659	0.942	0.638
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	6.0545	6.6511	0.46532	0.706	0.368
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	4.3888	7.5423	0.26146	0.795	0.564
startle / PPI	maximum startle response to full pulse (120 dB)	-29.626	88.631	0.0063051	0.889	0.740
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-109.22	93.842	-0.42663	0.491	0.251
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-43.803	90.566	-0.058180	0.779	0.631
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-71.305	76.481	-0.26871	0.571	0.357
startle / PPI	maximum startle response to pre-pulse, 74dB sound pressure level	-2.7188	2.0055	-0.75081	0.689	0.183
startle / PPI	maximum startle response to pre-pulse, 78dB sound pressure level	1.5694	1.8433	0.48414	0.803	0.400
startle / PPI	maximum startle response to pre-pulse, 82dB sound pressure level	7.2618	2.9370	0.97453	0.229	0.0178

MULTIPLE (CATEGORICAL) TRAIT PROFILE PLOT — Early Adult Phenotyping study (EAP)

Procedure	JaxKOMP-EAP Trait	Sex	Trait Effect	P-value
eye morphology	anterior chamber depth	females	1.0 %	1.0
eye morphology	anterior chamber depth	males	0.0 %	1.0
eye morphology	anterior chamber depth	both	1.0 %	1.0
eye morphology	bulging eye	females	1.0 %	1.0
eye morphology	bulging eye	males	0.0 %	1.0
eye morphology	bulging eye	both	1.0 %	1.00
eye morphology	cornea	females	4.0 %	1.0
eye morphology	cornea	males	2.0 %	1.0
eye morphology	cornea	both	3.0 %	1.00
eye morphology	cornea opacity	females	5.0 %	1.00
eye morphology	cornea opacity	males	1.0 %	1.0
eye morphology	cornea opacity	both	3.0 %	1.00
eye morphology	cornea vascularization	females	3.0 %	1.0
eye morphology	cornea vascularization	males	1.0 %	1.0
eye morphology	cornea vascularization	both	2.0 %	1.00
eye morphology	corneal deposits	females	2.0 %	1.0
eye morphology	corneal deposits	males	1.0 %	1.0
eye morphology	corneal deposits	both	1.0 %	1.00
eye morphology	corneal mineralization	females	2.0 %	1.0
eye morphology	corneal mineralization	males	1.0 %	1.0
eye morphology	corneal mineralization	both	1.0 %	1.00
eye morphology	corneal scleralization	females	3.0 %	1.00
eye morphology	corneal scleralization	males	1.0 %	1.0
eye morphology	corneal scleralization	both	2.0 %	1.00
eye morphology	corneal ulcer	females	1.0 %	1.0
eye morphology	corneal ulcer	males	1.0 %	1.0
eye morphology	corneal ulcer	both	1.0 %	1.00
eye morphology	eye closure	females	1.0 %	1.00
eye morphology	eye closure	males	0.0 %	1.0
eye morphology	eye closure	both	1.0 %	1.0
eye morphology	eye hemorrhage or blood presence	females	2.0 %	1.00
eye morphology	eye hemorrhage or blood presence	males	1.0 %	1.0
eye morphology	eye hemorrhage or blood presence	both	1.0 %	1.00
eye morphology	eyelid morphology	females	1.0 %	1.0
eye morphology	eyelid morphology	males	0.0 %	1.0
eye morphology	eyelid morphology	both	1.0 %	1.0
eye morphology	eyes (present, absent)	females	1.0 %	1.0
eye morphology	eyes (present, absent)	males	0.0 %	1.0
eye morphology	eyes (present, absent)	both	0.0 %	1.0
eye morphology	fusion between cornea and lens	females	4.0 %	1.00
eye morphology	fusion between cornea and lens	males	2.0 %	1.0
eye morphology	fusion between cornea and lens	both	3.0 %	1.00
eye morphology	iris pigmentation	females	2.0 %	1.0
eye morphology	iris pigmentation	males	1.0 %	1.0
eye morphology	iris pigmentation	both	2.0 %	1.00
eye morphology	iris transillumination	females	2.0 %	1.00
eye morphology	iris transillumination	males	1.0 %	1.0
eye morphology	iris transillumination	both	1.0 %	1.00
eye morphology	irispupil	females	4.0 %	1.00
eye morphology	irispupil	males	12.0 %	0.127
eye morphology	irispupil	both	5.0 %	0.301
eye morphology	lacrimation	females	3.0 %	1.0
eye morphology	lacrimation	males	2.0 %	1.0
eye morphology	lacrimation	both	3.0 %	1.0
eye morphology	lens	females	10.0 %	1.00
eye morphology	lens	males	8.0 %	1.0
eye morphology	lens	both	9.0 %	1.0
eye morphology	lens opacity	females	9.0 %	1.0
eye morphology	lens opacity	males	10.0 %	0.368
eye morphology	lens opacity	both	3.0 %	0.703
eye morphology	narrow eye opening	females	2.0 %	1.0
eye morphology	narrow eye opening	males	1.0 %	1.0
eye morphology	narrow eye opening	both	1.0 %	1.0
eye morphology	optic disc	females	4.0 %	1.00
eye morphology	optic disc	males	12.0 %	0.0619
eye morphology	optic disc	both	6.0 %	0.138
eye morphology	persistence of hyaloid vascular system	females	14.0 %	1.0
eye morphology	persistence of hyaloid vascular system	males	20.0 %	0.0205
eye morphology	persistence of hyaloid vascular system	both	6.0 %	0.247
eye morphology	pupil dilation	females	2.0 %	1.0
eye morphology	pupil dilation	males	1.0 %	1.0
eye morphology	pupil dilation	both	2.0 %	1.0
eye morphology	pupil light response	females	2.0 %	1.00
eye morphology	pupil light response	males	1.0 %	1.0
eye morphology	pupil light response	both	2.0 %	1.00
eye morphology	pupil position	females	4.0 %	1.00
eye morphology	pupil position	males	3.0 %	1.0
eye morphology	pupil position	both	4.0 %	1.00
eye morphology	pupil shape	females	3.0 %	1.00
eye morphology	pupil shape	males	2.0 %	1.0
eye morphology	pupil shape	both	3.0 %	1.00
eye morphology	retina	females	40.0 %	0.00434
eye morphology	retina	males	22.0 %	0.142
eye morphology	retina	both	31.0 %	0.00672
eye morphology	retinal blood vessels	females	4.0 %	1.0
eye morphology	retinal blood vessels	males	2.0 %	1.0
eye morphology	retinal blood vessels	both	3.0 %	1.0
eye morphology	retinal blood vessels pattern	females	5.0 %	1.0
eye morphology	retinal blood vessels pattern	males	2.0 %	1.0
eye morphology	retinal blood vessels pattern	both	4.0 %	1.00
eye morphology	retinal blood vessels structure	females	4.0 %	1.00
eye morphology	retinal blood vessels structure	males	2.0 %	1.0
eye morphology	retinal blood vessels structure	both	3.0 %	1.00
eye morphology	retinal pigmentation	females	12.0 %	1.0
eye morphology	retinal pigmentation	males	10.0 %	0.432
eye morphology	retinal pigmentation	both	7.0 %	0.738
eye morphology	retinal structure	females	4.0 %	1.00
eye morphology	retinal structure	males	2.0 %	1.0
eye morphology	retinal structure	both	3.0 %	1.00
eye morphology	synechia	females	4.0 %	1.0
eye morphology	synechia	males	2.0 %	1.0
eye morphology	synechia	both	3.0 %	1.00
eye morphology	vitreous	females	4.0 %	1.00
eye morphology	vitreous	males	2.0 %	1.0
eye morphology	vitreous	both	3.0 %	1.00
SHIRPA	activity body position	females	1.0 %	1.0
SHIRPA	activity body position	males	2.0 %	1.0
SHIRPA	activity body position	both	1.0 %	1.00
SHIRPA	aggression	females	0.0 %	1.00
SHIRPA	aggression	males	1.0 %	1.0
SHIRPA	aggression	both	1.0 %	1.0
SHIRPA	body length	females	0.0 %	1.0
SHIRPA	body length	males	0.0 %	1.0
SHIRPA	body length	both	0.0 %	1.00
SHIRPA	body position	females	0.0 %	1.0
SHIRPA	body position	males	1.0 %	1.0
SHIRPA	body position	both	0.0 %	1.00
SHIRPA	body thickness	females	1.0 %	1.0
SHIRPA	body thickness	males	0.0 %	1.0
SHIRPA	body thickness	both	0.0 %	1.0
SHIRPA	coat color abdomen	females	3.0 %	1.00
SHIRPA	coat color abdomen	males	4.0 %	1.0
SHIRPA	coat color abdomen	both	4.0 %	1.0
SHIRPA	coat color back	females	0.0 %	1.0
SHIRPA	coat color back	males	0.0 %	1.0
SHIRPA	coat color back	both	0.0 %	1.00
SHIRPA	coat color head	females	0.0 %	1.0
SHIRPA	coat color head	males	0.0 %	1.0
SHIRPA	coat color head	both	0.0 %	1.0
SHIRPA	coat color pattern abdomen	females	1.0 %	1.0
SHIRPA	coat color pattern abdomen	males	1.0 %	1.0
SHIRPA	coat color pattern abdomen	both	1.0 %	1.0
SHIRPA	coat color pattern back	females	0.0 %	1.0
SHIRPA	coat color pattern back	males	0.0 %	1.0
SHIRPA	coat color pattern back	both	0.0 %	1.0
SHIRPA	coat color pattern head	females	0.0 %	1.0
SHIRPA	coat color pattern head	males	0.0 %	1.0
SHIRPA	coat color pattern head	both	0.0 %	1.00
SHIRPA	coat hair abdomen texture appearance	females	2.0 %	1.0
SHIRPA	coat hair abdomen texture appearance	males	2.0 %	1.0
SHIRPA	coat hair abdomen texture appearance	both	2.0 %	1.0
SHIRPA	coat hair back texture appearance	females	0.0 %	1.0
SHIRPA	coat hair back texture appearance	males	0.0 %	1.0
SHIRPA	coat hair back texture appearance	both	0.0 %	1.0
SHIRPA	coat hair distribution abdomen	females	0.0 %	1.0
SHIRPA	coat hair distribution abdomen	males	1.0 %	1.0
SHIRPA	coat hair distribution abdomen	both	1.0 %	1.0
SHIRPA	coat hair distribution back	females	0.0 %	1.0
SHIRPA	coat hair distribution back	males	0.0 %	1.0
SHIRPA	coat hair distribution back	both	0.0 %	1.0
SHIRPA	coat hair distribution head	females	1.0 %	1.00
SHIRPA	coat hair distribution head	males	1.0 %	1.0
SHIRPA	coat hair distribution head	both	1.0 %	1.00
SHIRPA	coat hair head texture appearance	females	0.0 %	1.00
SHIRPA	coat hair head texture appearance	males	0.0 %	1.0
SHIRPA	coat hair head texture appearance	both	0.0 %	1.0
SHIRPA	contact righting	females	5.0 %	1.0
SHIRPA	contact righting	males	5.0 %	1.0
SHIRPA	contact righting	both	5.0 %	1.0
SHIRPA	ear morphology	females	0.0 %	1.0
SHIRPA	ear morphology	males	0.0 %	1.0
SHIRPA	ear morphology	both	0.0 %	1.0
SHIRPA	fat distribution	females	0.0 %	1.0
SHIRPA	fat distribution	males	0.0 %	1.0
SHIRPA	fat distribution	both	0.0 %	1.0
SHIRPA	forelimb digit number	females	0.0 %	1.00
SHIRPA	forelimb digit number	males	0.0 %	1.0
SHIRPA	forelimb digit number	both	0.0 %	1.0
SHIRPA	forelimb digit position	females	0.0 %	1.0
SHIRPA	forelimb digit position	males	0.0 %	1.0
SHIRPA	forelimb digit position	both	0.0 %	1.0
SHIRPA	forelimb digit shape	females	0.0 %	1.0
SHIRPA	forelimb digit shape	males	0.0 %	1.0
SHIRPA	forelimb digit shape	both	0.0 %	1.00
SHIRPA	forelimb digit size	females	0.0 %	1.0
SHIRPA	forelimb digit size	males	0.0 %	1.0
SHIRPA	forelimb digit size	both	0.0 %	1.00
SHIRPA	forelimb footpads	females	0.0 %	1.0
SHIRPA	forelimb footpads	males	0.0 %	1.0
SHIRPA	forelimb footpads	both	0.0 %	1.00
SHIRPA	forelimb nail length	females	0.0 %	1.0
SHIRPA	forelimb nail length	males	0.0 %	1.0
SHIRPA	forelimb nail length	both	0.0 %	1.0
SHIRPA	forelimb nail number	females	0.0 %	1.0
SHIRPA	forelimb nail number	males	0.0 %	1.0
SHIRPA	forelimb nail number	both	0.0 %	1.00
SHIRPA	forelimb nail position	females	0.0 %	1.0
SHIRPA	forelimb nail position	males	0.0 %	1.0
SHIRPA	forelimb nail position	both	0.0 %	1.0
SHIRPA	forelimb nail shape	females	0.0 %	1.0
SHIRPA	forelimb nail shape	males	0.0 %	1.0
SHIRPA	forelimb nail shape	both	0.0 %	1.0
SHIRPA	forelimbs position	females	0.0 %	1.0
SHIRPA	forelimbs position	males	0.0 %	1.0
SHIRPA	forelimbs position	both	0.0 %	1.0
SHIRPA	forelimbs shape	females	0.0 %	1.0
SHIRPA	forelimbs shape	males	0.0 %	1.0
SHIRPA	forelimbs shape	both	0.0 %	1.0
SHIRPA	forelimbs size	females	0.0 %	1.0
SHIRPA	forelimbs size	males	0.0 %	1.0
SHIRPA	forelimbs size	both	0.0 %	1.00
SHIRPA	forepaw position	females	0.0 %	1.0
SHIRPA	forepaw position	males	0.0 %	1.0
SHIRPA	forepaw position	both	0.0 %	1.0
SHIRPA	forepaw shape	females	0.0 %	1.0
SHIRPA	forepaw shape	males	0.0 %	1.0
SHIRPA	forepaw shape	both	0.0 %	1.0
SHIRPA	forepaw size	females	0.0 %	1.0
SHIRPA	forepaw size	males	0.0 %	1.0
SHIRPA	forepaw size	both	0.0 %	1.0
SHIRPA	gait (fluidity)	females	0.0 %	1.0
SHIRPA	gait (fluidity)	males	0.0 %	1.0
SHIRPA	gait (fluidity)	both	0.0 %	1.0
SHIRPA	genitalia morphology	females	0.0 %	1.00
SHIRPA	genitalia morphology	males	0.0 %	1.0
SHIRPA	genitalia morphology	both	0.0 %	1.0
SHIRPA	genitalia presence	females	0.0 %	1.0
SHIRPA	genitalia presence	males	0.0 %	1.0
SHIRPA	genitalia presence	both	0.0 %	1.00
SHIRPA	genitalia size	females	0.0 %	1.0
SHIRPA	genitalia size	males	0.0 %	1.0
SHIRPA	genitalia size	both	0.0 %	1.0
SHIRPA	head bobbing	females	0.0 %	1.0
SHIRPA	head bobbing	males	0.0 %	1.0
SHIRPA	head bobbing	both	0.0 %	1.00
SHIRPA	head morphology	females	0.0 %	1.0
SHIRPA	head morphology	males	0.0 %	1.0
SHIRPA	head morphology	both	0.0 %	1.00
SHIRPA	head size	females	0.0 %	1.0
SHIRPA	head size	males	0.0 %	1.0
SHIRPA	head size	both	0.0 %	1.0
SHIRPA	hindlimb digit number	females	1.0 %	1.00
SHIRPA	hindlimb digit number	males	0.0 %	1.0
SHIRPA	hindlimb digit number	both	0.0 %	1.0
SHIRPA	hindlimb digit position	females	0.0 %	1.0
SHIRPA	hindlimb digit position	males	0.0 %	1.0
SHIRPA	hindlimb digit position	both	0.0 %	1.00
SHIRPA	hindlimb digit shape	females	0.0 %	1.0
SHIRPA	hindlimb digit shape	males	0.0 %	1.0
SHIRPA	hindlimb digit shape	both	0.0 %	1.0
SHIRPA	hindlimb digit size	females	0.0 %	1.00
SHIRPA	hindlimb digit size	males	0.0 %	1.0
SHIRPA	hindlimb digit size	both	0.0 %	1.0
SHIRPA	hindlimb nail length	females	0.0 %	1.0
SHIRPA	hindlimb nail length	males	0.0 %	1.0
SHIRPA	hindlimb nail length	both	0.0 %	1.0
SHIRPA	hindlimb nail number	females	0.0 %	1.0
SHIRPA	hindlimb nail number	males	1.0 %	1.0
SHIRPA	hindlimb nail number	both	0.0 %	1.0
SHIRPA	hindlimb nail position	females	0.0 %	1.0
SHIRPA	hindlimb nail position	males	0.0 %	1.0
SHIRPA	hindlimb nail position	both	0.0 %	1.0
SHIRPA	hindlimb nail shape	females	0.0 %	1.0
SHIRPA	hindlimb nail shape	males	0.0 %	1.0
SHIRPA	hindlimb nail shape	both	0.0 %	1.0
SHIRPA	hindlimbs footpads	females	0.0 %	1.0
SHIRPA	hindlimbs footpads	males	0.0 %	1.0
SHIRPA	hindlimbs footpads	both	0.0 %	1.00
SHIRPA	hindlimbs position	females	0.0 %	1.0
SHIRPA	hindlimbs position	males	0.0 %	1.0
SHIRPA	hindlimbs position	both	0.0 %	1.0
SHIRPA	hindlimbs shape	females	0.0 %	1.0
SHIRPA	hindlimbs shape	males	0.0 %	1.0
SHIRPA	hindlimbs shape	both	0.0 %	1.0
SHIRPA	hindlimbs size	females	0.0 %	1.0
SHIRPA	hindlimbs size	males	0.0 %	1.0
SHIRPA	hindlimbs size	both	0.0 %	1.0
SHIRPA	hindpaw position	females	0.0 %	1.0
SHIRPA	hindpaw position	males	0.0 %	1.0
SHIRPA	hindpaw position	both	0.0 %	1.00
SHIRPA	hindpaw shape	females	0.0 %	1.0
SHIRPA	hindpaw shape	males	0.0 %	1.0
SHIRPA	hindpaw shape	both	0.0 %	1.00
SHIRPA	hindpaw size	females	0.0 %	1.0
SHIRPA	hindpaw size	males	0.0 %	1.0
SHIRPA	hindpaw size	both	0.0 %	1.00
SHIRPA	limb grasp	females	9.0 %	1.00
SHIRPA	limb grasp	males	6.0 %	1.0
SHIRPA	limb grasp	both	7.0 %	1.0
SHIRPA	lower lip morphology	females	0.0 %	1.0
SHIRPA	lower lip morphology	males	0.0 %	1.0
SHIRPA	lower lip morphology	both	0.0 %	1.00
SHIRPA	lower teeth appearance	females	0.0 %	1.0
SHIRPA	lower teeth appearance	males	0.0 %	1.0
SHIRPA	lower teeth appearance	both	0.0 %	1.0
SHIRPA	mouth morphology	females	0.0 %	1.0
SHIRPA	mouth morphology	males	0.0 %	1.0
SHIRPA	mouth morphology	both	0.0 %	1.0
SHIRPA	salivation	females	0.0 %	1.0
SHIRPA	salivation	males	0.0 %	1.0
SHIRPA	salivation	both	0.0 %	1.0
SHIRPA	skin color back paws	females	0.0 %	1.0
SHIRPA	skin color back paws	males	0.0 %	1.0
SHIRPA	skin color back paws	both	0.0 %	1.0
SHIRPA	skin color ear	females	0.0 %	1.0
SHIRPA	skin color ear	males	0.0 %	1.0
SHIRPA	skin color ear	both	0.0 %	1.0
SHIRPA	skin color front paws	females	0.0 %	1.0
SHIRPA	skin color front paws	males	0.0 %	1.0
SHIRPA	skin color front paws	both	0.0 %	1.0
SHIRPA	skin color snout	females	0.0 %	1.0
SHIRPA	skin color snout	males	0.0 %	1.0
SHIRPA	skin color snout	both	0.0 %	1.0
SHIRPA	skin color tail	females	0.0 %	1.0
SHIRPA	skin color tail	males	0.0 %	1.0
SHIRPA	skin color tail	both	0.0 %	1.00
SHIRPA	skin color whole body	females	0.0 %	1.0
SHIRPA	skin color whole body	males	0.0 %	1.0
SHIRPA	skin color whole body	both	0.0 %	1.00
SHIRPA	skin texture back paw	females	0.0 %	1.0
SHIRPA	skin texture back paw	males	0.0 %	1.0
SHIRPA	skin texture back paw	both	0.0 %	1.00
SHIRPA	skin texture ear	females	0.0 %	1.0
SHIRPA	skin texture ear	males	0.0 %	1.0
SHIRPA	skin texture ear	both	0.0 %	1.0
SHIRPA	skin texture front paws	females	0.0 %	1.0
SHIRPA	skin texture front paws	males	0.0 %	1.0
SHIRPA	skin texture front paws	both	0.0 %	1.0
SHIRPA	skin texture snout	females	0.0 %	1.0
SHIRPA	skin texture snout	males	0.0 %	1.0
SHIRPA	skin texture snout	both	0.0 %	1.0
SHIRPA	skin texture tail	females	0.0 %	1.0
SHIRPA	skin texture tail	males	0.0 %	1.0
SHIRPA	skin texture tail	both	0.0 %	1.0
SHIRPA	skin texture whole body	females	0.0 %	1.0
SHIRPA	skin texture whole body	males	0.0 %	1.0
SHIRPA	skin texture whole body	both	0.0 %	1.00
SHIRPA	snout size	females	0.0 %	1.0
SHIRPA	snout size	males	1.0 %	1.00
SHIRPA	snout size	both	0.0 %	1.0
SHIRPA	startle response	females	0.0 %	1.00
SHIRPA	startle response	males	0.0 %	1.00
SHIRPA	startle response	both	0.0 %	1.0
SHIRPA	tail curvature	females	0.0 %	1.00
SHIRPA	tail curvature	males	0.0 %	1.0
SHIRPA	tail curvature	both	0.0 %	1.0
SHIRPA	tail elevation	females	1.0 %	1.00
SHIRPA	tail elevation	males	2.0 %	1.0
SHIRPA	tail elevation	both	1.0 %	1.0
SHIRPA	tail length	females	0.0 %	1.0
SHIRPA	tail length	males	0.0 %	1.0
SHIRPA	tail length	both	0.0 %	1.0
SHIRPA	tail morphology	females	0.0 %	1.00
SHIRPA	tail morphology	males	0.0 %	1.0
SHIRPA	tail morphology	both	0.0 %	1.00
SHIRPA	tail presence	females	0.0 %	1.0
SHIRPA	tail presence	males	0.0 %	1.0
SHIRPA	tail presence	both	0.0 %	1.0
SHIRPA	tail shape	females	0.0 %	1.0
SHIRPA	tail shape	males	0.0 %	1.0
SHIRPA	tail shape	both	0.0 %	1.0
SHIRPA	tail thickness	females	0.0 %	1.0
SHIRPA	tail thickness	males	0.0 %	1.0
SHIRPA	tail thickness	both	0.0 %	1.0
SHIRPA	teeth presence	females	0.0 %	1.0
SHIRPA	teeth presence	males	0.0 %	1.0
SHIRPA	teeth presence	both	0.0 %	1.0
SHIRPA	transfer arousal	females	1.0 %	1.0
SHIRPA	transfer arousal	males	2.0 %	1.0
SHIRPA	transfer arousal	both	1.0 %	1.0
SHIRPA	tremor	females	0.0 %	1.0
SHIRPA	tremor	males	0.0 %	1.0
SHIRPA	tremor	both	0.0 %	1.0
SHIRPA	trunk curl	females	0.0 %	1.00
SHIRPA	trunk curl	males	0.0 %	1.0
SHIRPA	trunk curl	both	0.0 %	1.0
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	females	0.0 %	1.0
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	males	0.0 %	1.0
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	both	0.0 %	1.0
SHIRPA	upper lip morphology	females	0.0 %	1.0
SHIRPA	upper lip morphology	males	0.0 %	1.0
SHIRPA	upper lip morphology	both	0.0 %	1.0
SHIRPA	upper teeth appearance	females	0.0 %	1.0
SHIRPA	upper teeth appearance	males	0.0 %	1.0
SHIRPA	upper teeth appearance	both	0.0 %	1.0
SHIRPA	vibrissae appearance	females	2.0 %	1.0
SHIRPA	vibrissae appearance	males	1.0 %	1.0
SHIRPA	vibrissae appearance	both	1.0 %	1.0
SHIRPA	vibrissae presence	females	2.0 %	1.00
SHIRPA	vibrissae presence	males	1.0 %	1.00
SHIRPA	vibrissae presence	both	2.0 %	1.0
SHIRPA	vocalization	females	2.0 %	1.00
SHIRPA	vocalization	males	2.0 %	1.00
SHIRPA	vocalization	both	2.0 %	1.0

GENOTYPE CORRELATION PLOT

Correlate Smg9^em1(IMPC)J -/+ with genotype: