MPD: JaxKOMP-EAP genotype: Ffar2<sup>tm1b(EUCOMM)Hmgu</sup> -/-

JaxKOMP-EAP effect sizes: Ffar2^{tm1b(EUCOMM)Hmgu} -/- Gene Ffar2

MULTIPLE (NUMERIC) TRAIT PROFILE PLOT — Early Adult Phenotyping study (EAP)

Procedure	JaxKOMP-EAP Trait	Trait Effect	Trait Effect SE	Trait Effect RankZ	Adjusted p-value	Unadjusted p-value
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 6 kHz pip	-1.8021	1.8583	-0.78154	0.754	0.353
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 12 kHz pip	-0.46288	1.4512	-0.082988	0.933	0.756
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 18 kHz pip	3.0054	3.7023	0.44689	0.761	0.433
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 24 kHz pip	-0.88995	2.7913	-0.25248	0.910	0.755
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 30 kHz pip	-11.422	4.7707	-1.4806	0.277	0.0339
body composition	body length	0.020256	0.042207	0.48462	0.828	0.633
body composition	body weight (at time of DXA)	-0.45258	0.52110	-0.25588	0.610	0.389
body composition	bone area, whole body scan, head excluded	0.26164	0.12865	1.3217	0.209	0.0475
body composition	bone mineral content of whole body scan, head excluded	0.011670	0.0090156	0.81888	0.477	0.202
body composition	bone mineral content to body weight ratio	0.00044195	0.00039964	0.78313	0.553	0.274
body composition	bone mineral density of whole body scan, head excluded	0.00018190	0.00046601	0.22944	0.861	0.698
body composition	fat tissue mass of whole body scan, head excluded	-0.028386	0.24735	-0.043702	0.961	0.909
body composition	fat tissue mass to body weight ratio	-0.0073149	0.0099960	-0.29788	0.687	0.468
body composition	lean tissue mass of whole body scan, head excluded	-0.086555	0.22144	-0.33954	0.877	0.698
body composition	lean tissue mass to body weight ratio	-0.010588	0.0087038	-0.63180	0.485	0.230
body composition	percent fat, whole body scan, head excluded	-0.47585	0.96958	-0.16734	0.807	0.626
body composition	ratio of soft-tissue attenuation coefficients	0.00055011	0.0010778	0.18578	0.797	0.612
body composition	tissue area	0.19453	0.16759	0.80480	0.552	0.251
body composition	total tissue mass, whole body scan, head excluded	-0.10241	0.17363	-0.46545	0.756	0.558
clinical blood chemistry	alanine transaminase (plasma ALT)	95.343	42.966	2.4685	0.330	0.0396
clinical blood chemistry	albumin (plasma Alb)	-0.20588	0.48596	-0.25070	0.877	0.677
clinical blood chemistry	alkaline phosphatase (plasma ALP)	21.585	5.8961	2.1347	0.0243	0.00194
clinical blood chemistry	aspartate transaminase (plasma AST)	82.665	62.455	2.0463	0.524	0.202
clinical blood chemistry	aspartate transaminase to alanine transaminase ratio (plasma AST:ALT)	0.0031401	0.37465	0.038333	0.997	0.993
clinical blood chemistry	blood urea nitrogen (BUN)	-5.6538	4.8746	-1.8681	0.530	0.263
clinical blood chemistry	calcium (plasma Ca)	0.12108	0.13676	1.1431	0.627	0.388
clinical blood chemistry	carbon dioxide (plasma CO₂)	-0.97108	0.77031	-1.1920	0.507	0.224
clinical blood chemistry	chloride (plasma Cl)	3.0278	0.89765	1.9972	0.0225	0.00361
clinical blood chemistry	glucose (plasma GLU, no fast)	17.260	21.461	0.96628	0.636	0.432
clinical blood chemistry	HDL cholesterol (plasma HDL)	2.6833	3.6418	0.31920	0.747	0.471
clinical blood chemistry	HDL cholesterol to total cholesterol ratio	-0.0027922	0.017599	-0.32820	0.969	0.876
clinical blood chemistry	iron (plasma Fe)	0.028397	0.013123	2.2729	0.225	0.0459
clinical blood chemistry	non-esterified fatty acids (plasma NEFA)	0.016320	0.20575	0.17268	0.975	0.938
clinical blood chemistry	phosphorus (plasma phosphate)	0.69582	0.40569	0.99082	0.334	0.107
clinical blood chemistry	potassium (plasma K)	0.29560	0.33808	0.17032	0.554	0.393
clinical blood chemistry	sodium (plasma Na)	1.8066	1.0659	0.73103	0.197	0.107
clinical blood chemistry	total bilirubin (plasma TBIL)	0.027454	0.027093	1.5043	0.678	0.324
clinical blood chemistry	total cholesterol (plasma CHOL, no fast)	2.4654	6.5634	0.21273	0.894	0.712
clinical blood chemistry	total protein (plasma TP)	-1.0342	1.3231	-0.88345	0.689	0.446
clinical blood chemistry	triglyceride (plasma TG, no fast)	20.481	10.195	1.2166	0.260	0.0629
EKG	duration of PQ interval	0.0027778	0.72724	0.16394	0.999	0.997
EKG	duration of PR interval	0.12821	0.77151	0.21112	0.975	0.869
EKG	duration of QRS interval	0.36142	0.36280	0.89690	0.885	0.325
EKG	duration of QT interval	-1.0102	0.78514	-0.80709	0.694	0.206
EKG	duration of QTC interval, calculated by dividing QT interval by square root of preceding RR interval	-0.43820	0.69288	-0.42117	0.925	0.531
EKG	duration of RR interval	-1.9774	1.2359	-0.76861	0.528	0.118
EKG	duration of ST interval	-1.3432	0.71521	-1.0918	0.520	0.0681
EKG	heart rate coefficient of variation (signal intensity)	0.46951	1.1437	0.46563	0.948	0.684
EKG	heart rate variability, mean of differences between sequential beats; beats per min	4.4351	8.2006	0.60283	0.931	0.592
EKG	heart rate, beats per min	19.854	9.7103	0.98093	0.360	0.0479
EKG	mean R amplitude, mean amplitude of signal measured from isoelectric line to peak of QRS	-0.14638	0.080505	-1.2693	0.383	0.0771
EKG	mean SR amplitude, mean amplitude of signal measured from signal minimum line to peak of QRS	-0.21385	0.10341	-1.2829	0.298	0.0455
EKG	number of signals	-7.1667	4.1265	-1.3210	0.605	0.0905
EKG	proportion of number pairs of successive beat-to-beat intervals that exceed 50 ms	2.3384	4.2827	0.51184	0.898	0.588
EKG	QT dispersion, measured as inter-lead variability of QT intervals	-1.5243	4.5097	-0.42557	0.968	0.737
EKG	QTc dispersion, calculated as rate-corrected QT dispersion	-1.5399	5.2736	-0.40799	0.966	0.772
EKG	root mean square of successive differences of neighboring RR intervals	1.8354	2.2881	1.0112	0.884	0.427
electroretinography	a-wave amplitude of rod photoreceptors, left	13.058	18.962	0.18001	0.789	0.503
electroretinography	a-wave amplitude of rod photoreceptors, right	46.522	23.749	1.9145	0.438	0.0719
electroretinography	b-wave amplitude of cone photoreceptors, left	19.968	12.548	1.4476	0.672	0.136
electroretinography	b-wave amplitude of cone photoreceptors, right	-24.115	18.749	-1.5172	0.714	0.221
electroretinography	b-wave amplitude of rod photoreceptors, left	28.816	46.099	0.85769	0.797	0.543
electroretinography	b-wave amplitude of rod photoreceptors, right	-104.73	70.160	-1.5905	0.504	0.159
electroretinography	b-wave implicit time of rod photoreceptors (interval from onset of stimulus to peak of the wave), left	0.40000	0.65584	0.20476	0.864	0.552
electroretinography	b-wave implicit time of rod photoreceptors (interval from onset of stimulus to peak of the wave), right	-10.452	5.2364	-1.9367	0.432	0.0673
electroretinography	rod a wave implicit time, left	0.49091	0.50161	0.21753	0.738	0.346
electroretinography	rod a wave implicit time, right	-5.4646	2.9140	-2.5010	0.399	0.0834
electroretinography	rod b wave implicit time, left	2.8642	1.0375	1.1989	0.244	0.0162
electroretinography	rod b wave implicit time, right	-10.912	7.0601	-2.1860	0.612	0.146
glucose tolerance test	amount glucose injected	-0.41499	1.7307	0.24512	0.938	0.812
glucose tolerance test	plasma glucose, 0min	7.4851	6.4760	0.54149	0.466	0.253
glucose tolerance test	plasma glucose, 15min	-5.7770	22.518	-0.053563	0.935	0.799
glucose tolerance test	plasma glucose, 30min	-69.545	22.166	-1.8329	0.0542	0.00294
glucose tolerance test	plasma glucose, 60min	-54.170	16.108	-1.9207	0.0454	0.00154
glucose tolerance test	plasma glucose, 120min	5.4606	6.2482	0.23835	0.670	0.387
heart weight	heart weight, normalized to body weight	-0.21775	0.16458	-1.2800	0.401	0.192
heart weight	heart weight, weight	-6.5780	4.1485	-1.2709	0.298	0.120
hematology	basophil differential (percent of total WBC)	0.14446	0.048528	1.6793	0.197	0.00808
hematology	calculated hemoglobin (cHGB)	0.24783	0.39696	0.49196	0.771	0.540
hematology	eosinophil differential (percent of total WBC)	0.28333	0.29275	0.85455	0.729	0.346
hematology	hematocrit (HCT)	0.039423	0.72061	-0.33703	0.979	0.957
hematology	hemoglobin concentration distribution width (HDW)	-0.13868	0.028795	-2.6387	0.00726	0.000161
hematology	large unstained cells (percent of total WBC)	-0.21831	0.083566	-1.3402	0.197	0.0176
hematology	lymphocyte differential (percent of total WBC)	6.3648	4.9270	1.8972	0.468	0.213
hematology	mean corpuscular hemoglobin (CHr)	0.040286	0.084675	0.35946	0.821	0.640
hematology	mean platelet volume (MPV)	0.063095	0.11094	0.23751	0.773	0.577
hematology	mean RBC corpuscular hemoglobin (MCH)	-0.69098	1.1343	-1.3344	0.811	0.550
hematology	mean RBC corpuscular hemoglobin concentration (MCHC)	-1.4456	2.5149	-1.4844	0.826	0.573
hematology	mean RBC corpuscular volume (MCV)	0.027145	0.55495	0.064282	0.981	0.962
hematology	measured hemoglobin (mHGB)	-0.69754	1.2192	-1.4038	0.791	0.574
hematology	monocyte differential (percent of total WBC)	0.052732	0.16745	0.39698	0.912	0.756
hematology	neutrophil differential (percent of total WBC)	-6.5399	5.0484	-2.0730	0.463	0.212
hematology	platelet count (PLT; units per volume x 10³)	-168.46	58.304	-1.8423	0.140	0.00977
hematology	RBC corpuscular distribution width (RDW)	-0.11175	0.15949	-0.40481	0.718	0.492
hematology	RBC corpuscular hemoglobin concentration mean (CHCM)	-0.014637	0.55943	-0.055732	0.989	0.979
hematology	red blood cell count (RBC; per volume x 10⁶)	0.036776	0.17007	-0.19135	0.923	0.831
hematology	reticulocyte count (Retic; units per volume x 10⁹)	-41.299	17.117	-1.4871	0.278	0.0267
hematology	reticulocyte differential (percent of total RBC)	-0.42281	0.16021	-1.4507	0.220	0.0167
hematology	white blood cell count (WBC; units per volume x 10³)	-0.75068	0.66485	-0.36318	0.480	0.274
holeboard	number of hole pokes by individual hole number, 20 min test, 1	-0.95092	0.73973	-0.90591	0.688	0.206
holeboard	number of hole pokes by individual hole number, 20 min test, 2	-0.56710	0.47761	-0.75345	0.766	0.242
holeboard	number of hole pokes by individual hole number, 20 min test, 3	0.72891	0.49179	1.1557	0.662	0.146
holeboard	number of hole pokes by individual hole number, 20 min test, 4	-0.46683	0.88182	-0.39580	0.885	0.599
holeboard	number of hole pokes by individual hole number, 20 min test, 5	-0.39512	0.52250	-0.54877	0.849	0.454
holeboard	number of hole pokes by individual hole number, 20 min test, 6	-0.13574	0.25832	-0.36019	0.930	0.602
holeboard	number of hole pokes by individual hole number, 20 min test, 7	-0.059744	0.23845	-0.18787	0.983	0.803
holeboard	number of hole pokes by individual hole number, 20 min test, 8	-0.39913	0.39804	-0.55663	0.799	0.322
holeboard	number of hole pokes by individual hole number, 20 min test, 9	-0.50268	0.47518	-0.80558	0.772	0.296
holeboard	number of hole pokes by individual hole number, 20 min test, 10	-0.67523	0.40028	-1.8657	0.699	0.0992
holeboard	number of hole pokes by individual hole number, 20 min test, 11	0.058282	0.25902	0.17658	0.971	0.823
holeboard	number of hole pokes by individual hole number, 20 min test, 12	-0.86964	0.40460	-1.3073	0.386	0.0376
holeboard	number of hole pokes by individual hole number, 20 min test, 13	-0.019939	0.78525	0.055694	0.999	0.980
holeboard	number of hole pokes by individual hole number, 20 min test, 14	0.042063	0.36980	0.14388	0.984	0.910
holeboard	number of hole pokes by individual hole number, 20 min test, 15	0.15125	0.43677	0.29609	0.914	0.731
holeboard	number of hole pokes by individual hole number, 20 min test, 16	-1.3050	0.65142	-1.1398	0.408	0.0520
holeboard	total number of hole pokes, 20 min test	-5.4624	3.7112	-0.67555	0.420	0.149
light / dark	fecal boli count, 20 min test	0.26026	0.82367	0.31331	0.927	0.753
light / dark	latency to enter dark zone, 20 min test	72.459	45.131	1.1549	0.551	0.115
light / dark	number of transitions between light and dark zones, 20 min test	-4.4044	5.3485	-0.33754	0.706	0.414
light / dark	percentage of total time in dark zone, 20 min test	-6.5924	4.4302	-1.0320	0.509	0.143
light / dark	percentage of total time in light zone, 20 min test	6.5924	4.4302	1.0275	0.508	0.143
light / dark	time mobile in dark zone, 20 min test	3.3131	11.765	0.12198	0.905	0.779
light / dark	time mobile in light zone, 20 min test	10.541	9.4686	0.42628	0.534	0.271
light / dark	time spent in dark zone, 20 min test	-79.173	59.248	-0.95029	0.619	0.188
light / dark	time spent in light zone, 20 min test	79.173	59.248	0.95029	0.619	0.188
sleep	differential wake percentages during light and dark phase	0.89212	0.98114	1.6179	0.810	0.377
sleep	mean breath rate during-sleep	-0.17306	0.074654	-1.2278	0.185	0.0340
sleep	mean of sleep bout lengths	-47.701	31.288	-0.87401	0.461	0.147
sleep	mean of sleep bout lengths with lights off	-6.9313	30.256	0.071387	0.945	0.822
sleep	mean of sleep bout lengths with lights on	-52.055	48.118	-0.83006	0.666	0.295
sleep	mean percentage of time sleeping over 24 h periods	2.1021	1.2874	1.3699	0.724	0.122
sleep	mean percentage of time sleeping with lights on	3.0935	2.4459	1.5138	0.591	0.224
sleep	mean percentage of time spent sleeping with lights off	1.1104	1.8213	0.18445	0.879	0.551
sleep	peak wake with respect to dark onset median	-0.47020	0.49027	-0.63037	0.860	0.353
sleep	percentage of time awake one hour before and after light onset	-5.1165	6.2255	-0.34286	0.746	0.423
startle / PPI	average baseline movement during background noise	-2.1560	1.5725	-1.4603	0.720	0.178
startle / PPI	average of each corrected maximum percent pre-pulse inhibition value	-0.17634	0.078508	-1.6207	0.253	0.0301
startle / PPI	average of each corrected percent pre-pulse inhibition value	-0.17699	0.077717	-1.7944	0.240	0.0281
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-10.097	10.060	-1.0469	0.879	0.321
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-21.572	7.0355	-2.0747	0.138	0.00383
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-20.612	6.4589	-1.8863	0.0615	0.00272
startle / PPI	average startle response to full pulse (120 dB)	260.53	86.649	2.7110	0.0376	0.00449
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	316.25	85.301	2.9333	0.00874	0.000621
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	315.80	84.926	3.0570	0.00910	0.000601
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	255.23	76.134	2.7110	0.0200	0.00173
startle / PPI	average startle response to pre-pulse, 74dB sound pressure level	-3.0190	2.2018	-1.9206	0.709	0.178
startle / PPI	average startle response to pre-pulse, 78dB sound pressure level	0.59511	2.0690	0.42050	0.961	0.775
startle / PPI	average startle response to pre-pulse, 82dB sound pressure level	2.0328	2.6557	0.70875	0.799	0.448
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-0.091852	0.11594	-0.82536	0.897	0.433
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-0.22171	0.076610	-1.8459	0.129	0.00607
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-0.21739	0.070193	-1.8309	0.0472	0.00352
startle / PPI	corrected average startle response to full pulse (120 dB) minus average baseline movement during background noise	262.76	86.452	2.7110	0.0359	0.00412
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 74dB sound pressure level	319.37	85.170	2.9333	0.00783	0.000547
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 78dB sound pressure level	315.33	84.724	3.0570	0.00879	0.000595
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 82dB sound pressure level	253.40	75.700	2.8428	0.0201	0.00176
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-0.093760	0.11305	-0.80388	0.884	0.412
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-0.22145	0.079882	-1.7223	0.156	0.00834
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-0.21381	0.071479	-1.6636	0.0533	0.00468
startle / PPI	corrected maximum startle response to full pulse (120 dB) minus maximum baseline movement during background noise	314.41	88.578	1.4936	0.0126	0.00100
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 74dB sound pressure level	362.08	89.708	1.6473	0.00398	0.000238
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 78dB sound pressure level	365.06	88.571	1.6925	0.00358	0.000178
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 82dB sound pressure level	293.35	76.225	1.6259	0.00761	0.000418
startle / PPI	maximum baseline movement during background noise	-3.2730	1.9050	-0.90692	0.560	0.0933
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-9.8575	10.161	-0.93475	0.890	0.338
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-21.608	7.3729	-1.8947	0.147	0.00551
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-20.197	6.6299	-1.7543	0.0623	0.00404
startle / PPI	maximum startle response to full pulse (120 dB)	311.46	88.503	1.4809	0.0133	0.00110
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	358.51	89.875	1.6419	0.00455	0.000275
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	364.74	88.763	1.6925	0.00363	0.000185
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	297.33	76.621	1.6473	0.00687	0.000380
startle / PPI	maximum startle response to pre-pulse, 74dB sound pressure level	-3.4537	2.2913	-0.93475	0.642	0.139
startle / PPI	maximum startle response to pre-pulse, 78dB sound pressure level	-0.084995	2.1333	-0.010509	0.996	0.968
startle / PPI	maximum startle response to pre-pulse, 82dB sound pressure level	3.6327	3.0221	0.48100	0.620	0.236
urinalysis	albumin-creatinine ratio (urine ACR)	4.1442	1.6765	0.69789	0.0946	0.0171
urinalysis	creatinine (urine CREA)	-3.4585	2.8675	0.057000	0.466	0.234
urinalysis	glucose (urine GLU)	-0.99138	2.1273	-0.36611	0.874	0.643
urinalysis	magnesium level (urine Mg)	-0.016047	0.025004	-0.46697	0.824	0.524
urinalysis	microalbumin (urine MA), calculated	0.13669	0.12028	0.32188	0.551	0.262

MULTIPLE (CATEGORICAL) TRAIT PROFILE PLOT — Early Adult Phenotyping study (EAP)

In this plot, data points are the computed genotype effect % vs. C57BL/6NJ controls, for all measured categorical phenotypes in JaxKOMP-EAP

Dimensions Width: × Height: px

Plot Options Group by Procedure

Include Sexes Data Both Females Males

Significance Threshold p-Value Threshold

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Procedure	JaxKOMP-EAP Trait	Sex	Trait Effect	P-value

electroretinography	blind eyes, left	females	0.0 %	1.0
electroretinography	blind eyes, left	males	0.0 %	1.0
electroretinography	blind eyes, left	both	0.0 %	1.0
electroretinography	blind eyes, right	females	50.0 %	0.00990
electroretinography	blind eyes, right	males	0.0 %	1.0
electroretinography	blind eyes, right	both	25.0 %	0.00978
eye morphology	anterior chamber depth	females	12.0 %	0.0556
eye morphology	anterior chamber depth	males	0.0 %	1.0
eye morphology	anterior chamber depth	both	6.0 %	0.0613
eye morphology	bulging eye	females	12.0 %	0.0359
eye morphology	bulging eye	males	0.0 %	1.0
eye morphology	bulging eye	both	6.0 %	0.0409
eye morphology	cornea	females	12.0 %	0.0773
eye morphology	cornea	males	2.0 %	1.0
eye morphology	cornea	both	6.0 %	0.109
eye morphology	cornea opacity	females	12.0 %	0.0695
eye morphology	cornea opacity	males	1.0 %	1.0
eye morphology	cornea opacity	both	6.0 %	0.0690
eye morphology	cornea vascularization	females	12.0 %	0.0534
eye morphology	cornea vascularization	males	1.0 %	1.0
eye morphology	cornea vascularization	both	6.0 %	0.0695
eye morphology	corneal deposits	females	12.0 %	0.0944
eye morphology	corneal deposits	males	1.0 %	1.0
eye morphology	corneal deposits	both	6.0 %	0.105
eye morphology	corneal mineralization	females	12.0 %	0.103
eye morphology	corneal mineralization	males	1.0 %	1.0
eye morphology	corneal mineralization	both	6.0 %	0.0612
eye morphology	corneal scleralization	females	12.0 %	0.0656
eye morphology	corneal scleralization	males	1.0 %	1.0
eye morphology	corneal scleralization	both	6.0 %	0.0897
eye morphology	corneal ulcer	females	12.0 %	0.0595
eye morphology	corneal ulcer	males	1.0 %	1.0
eye morphology	corneal ulcer	both	6.0 %	0.0738
eye morphology	eye closure	females	12.0 %	0.0358
eye morphology	eye closure	males	0.0 %	1.0
eye morphology	eye closure	both	6.0 %	0.0408
eye morphology	eye hemorrhage or blood presence	females	12.0 %	0.0696
eye morphology	eye hemorrhage or blood presence	males	1.0 %	1.0
eye morphology	eye hemorrhage or blood presence	both	6.0 %	0.0885
eye morphology	eyelid morphology	females	12.0 %	0.0443
eye morphology	eyelid morphology	males	0.0 %	1.0
eye morphology	eyelid morphology	both	6.0 %	0.0494
eye morphology	eyes (present, absent)	females	12.0 %	0.0433
eye morphology	eyes (present, absent)	males	0.0 %	1.0
eye morphology	eyes (present, absent)	both	6.0 %	0.0493
eye morphology	fusion between cornea and lens	females	11.0 %	0.144
eye morphology	fusion between cornea and lens	males	2.0 %	1.0
eye morphology	fusion between cornea and lens	both	6.0 %	0.179
eye morphology	iris pigmentation	females	12.0 %	0.166
eye morphology	iris pigmentation	males	1.0 %	1.0
eye morphology	iris pigmentation	both	6.0 %	0.142
eye morphology	iris transillumination	females	12.0 %	0.146
eye morphology	iris transillumination	males	1.0 %	1.0
eye morphology	iris transillumination	both	6.0 %	0.116
eye morphology	irispupil	females	12.0 %	0.193
eye morphology	irispupil	males	3.0 %	1.0
eye morphology	irispupil	both	6.0 %	0.171
eye morphology	lacrimation	females	11.0 %	0.244
eye morphology	lacrimation	males	2.0 %	1.0
eye morphology	lacrimation	both	6.0 %	0.248
eye morphology	lens	females	28.0 %	0.0331
eye morphology	lens	males	9.0 %	0.496
eye morphology	lens	both	16.0 %	0.0402
eye morphology	lens opacity	females	11.0 %	0.251
eye morphology	lens opacity	males	6.0 %	1.0
eye morphology	lens opacity	both	6.0 %	0.357
eye morphology	narrow eye opening	females	12.0 %	0.0486
eye morphology	narrow eye opening	males	1.0 %	1.0
eye morphology	narrow eye opening	both	6.0 %	0.0556
eye morphology	optic disc	females	11.0 %	0.180
eye morphology	optic disc	males	2.0 %	1.0
eye morphology	optic disc	both	5.0 %	0.241
eye morphology	persistence of hyaloid vascular system	females	11.0 %	0.131
eye morphology	persistence of hyaloid vascular system	males	5.0 %	1.0
eye morphology	persistence of hyaloid vascular system	both	6.0 %	0.184
eye morphology	pupil dilation	females	12.0 %	0.171
eye morphology	pupil dilation	males	1.0 %	1.0
eye morphology	pupil dilation	both	6.0 %	0.162
eye morphology	pupil light response	females	11.0 %	0.179
eye morphology	pupil light response	males	1.0 %	1.0
eye morphology	pupil light response	both	6.0 %	0.236
eye morphology	pupil position	females	12.0 %	0.213
eye morphology	pupil position	males	3.0 %	1.0
eye morphology	pupil position	both	6.0 %	0.186
eye morphology	pupil shape	females	12.0 %	0.176
eye morphology	pupil shape	males	2.0 %	1.0
eye morphology	pupil shape	both	6.0 %	0.185
eye morphology	retina	females	11.0 %	0.288
eye morphology	retina	males	9.0 %	0.417
eye morphology	retina	both	6.0 %	0.253
eye morphology	retinal blood vessels	females	11.0 %	0.154
eye morphology	retinal blood vessels	males	2.0 %	1.0
eye morphology	retinal blood vessels	both	5.0 %	0.196
eye morphology	retinal blood vessels pattern	females	11.0 %	0.216
eye morphology	retinal blood vessels pattern	males	2.0 %	1.0
eye morphology	retinal blood vessels pattern	both	5.0 %	0.279
eye morphology	retinal blood vessels structure	females	11.0 %	0.165
eye morphology	retinal blood vessels structure	males	2.0 %	1.0
eye morphology	retinal blood vessels structure	both	5.0 %	0.215
eye morphology	retinal pigmentation	females	38.0 %	0.00675
eye morphology	retinal pigmentation	males	14.0 %	1.0
eye morphology	retinal pigmentation	both	14.0 %	0.0787
eye morphology	retinal structure	females	46.0 %	4.17e-7
eye morphology	retinal structure	males	2.0 %	1.0
eye morphology	retinal structure	both	22.0 %	0.00000223
eye morphology	synechia	females	11.0 %	0.161
eye morphology	synechia	males	2.0 %	1.0
eye morphology	synechia	both	5.0 %	0.200
eye morphology	vitreous	females	11.0 %	0.152
eye morphology	vitreous	males	2.0 %	1.0
eye morphology	vitreous	both	5.0 %	0.189
rotarod	outcome of accelerating rotarod (4-40 rpm/ 5 min) over 5 trials	females	0.0 %	1.0
rotarod	outcome of accelerating rotarod (4-40 rpm/ 5 min) over 5 trials	males	0.0 %	1.0
rotarod	outcome of accelerating rotarod (4-40 rpm/ 5 min) over 5 trials	both	0.0 %	1.0
rotarod	trial number	females	0.0 %	1.0
rotarod	trial number	males	0.0 %	1.0
rotarod	trial number	both	0.0 %	1.0
SHIRPA	activity body position	females	1.0 %	1.0
SHIRPA	activity body position	males	2.0 %	1.0
SHIRPA	activity body position	both	1.0 %	1.00
SHIRPA	aggression	females	0.0 %	1.00
SHIRPA	aggression	males	1.0 %	1.0
SHIRPA	aggression	both	1.0 %	1.0
SHIRPA	body length	females	0.0 %	1.0
SHIRPA	body length	males	0.0 %	1.00
SHIRPA	body length	both	0.0 %	1.00
SHIRPA	body position	females	0.0 %	1.0
SHIRPA	body position	males	1.0 %	1.0
SHIRPA	body position	both	0.0 %	1.0
SHIRPA	body thickness	females	1.0 %	1.0
SHIRPA	body thickness	males	0.0 %	1.0
SHIRPA	body thickness	both	0.0 %	1.0
SHIRPA	coat color abdomen	females	3.0 %	1.00
SHIRPA	coat color abdomen	males	4.0 %	1.0
SHIRPA	coat color abdomen	both	4.0 %	1.0
SHIRPA	coat color back	females	0.0 %	1.0
SHIRPA	coat color back	males	0.0 %	1.00
SHIRPA	coat color back	both	0.0 %	1.00
SHIRPA	coat color head	females	0.0 %	1.0
SHIRPA	coat color head	males	0.0 %	1.00
SHIRPA	coat color head	both	0.0 %	1.0
SHIRPA	coat color pattern abdomen	females	1.0 %	1.0
SHIRPA	coat color pattern abdomen	males	1.0 %	1.0
SHIRPA	coat color pattern abdomen	both	1.0 %	1.0
SHIRPA	coat color pattern back	females	0.0 %	1.0
SHIRPA	coat color pattern back	males	0.0 %	1.00
SHIRPA	coat color pattern back	both	0.0 %	1.0
SHIRPA	coat color pattern head	females	0.0 %	1.0
SHIRPA	coat color pattern head	males	0.0 %	1.0
SHIRPA	coat color pattern head	both	0.0 %	1.00
SHIRPA	coat hair abdomen texture appearance	females	2.0 %	1.0
SHIRPA	coat hair abdomen texture appearance	males	2.0 %	1.0
SHIRPA	coat hair abdomen texture appearance	both	2.0 %	1.0
SHIRPA	coat hair back texture appearance	females	0.0 %	1.0
SHIRPA	coat hair back texture appearance	males	0.0 %	1.0
SHIRPA	coat hair back texture appearance	both	0.0 %	1.0
SHIRPA	coat hair distribution abdomen	females	0.0 %	1.0
SHIRPA	coat hair distribution abdomen	males	1.0 %	1.00
SHIRPA	coat hair distribution abdomen	both	1.0 %	1.00
SHIRPA	coat hair distribution back	females	0.0 %	1.0
SHIRPA	coat hair distribution back	males	0.0 %	1.0
SHIRPA	coat hair distribution back	both	0.0 %	1.0
SHIRPA	coat hair distribution head	females	1.0 %	1.00
SHIRPA	coat hair distribution head	males	1.0 %	1.0
SHIRPA	coat hair distribution head	both	1.0 %	1.0
SHIRPA	coat hair head texture appearance	females	0.0 %	1.00
SHIRPA	coat hair head texture appearance	males	0.0 %	1.0
SHIRPA	coat hair head texture appearance	both	0.0 %	1.0
SHIRPA	contact righting	females	5.0 %	1.0
SHIRPA	contact righting	males	5.0 %	1.00
SHIRPA	contact righting	both	5.0 %	1.00
SHIRPA	ear morphology	females	0.0 %	1.0
SHIRPA	ear morphology	males	0.0 %	1.0
SHIRPA	ear morphology	both	0.0 %	1.0
SHIRPA	fat distribution	females	0.0 %	1.0
SHIRPA	fat distribution	males	0.0 %	1.0
SHIRPA	fat distribution	both	0.0 %	1.00
SHIRPA	forelimb digit number	females	0.0 %	1.00
SHIRPA	forelimb digit number	males	0.0 %	1.0
SHIRPA	forelimb digit number	both	0.0 %	1.00
SHIRPA	forelimb digit position	females	0.0 %	1.0
SHIRPA	forelimb digit position	males	0.0 %	1.0
SHIRPA	forelimb digit position	both	0.0 %	1.0
SHIRPA	forelimb digit shape	females	0.0 %	1.0
SHIRPA	forelimb digit shape	males	0.0 %	1.0
SHIRPA	forelimb digit shape	both	0.0 %	1.0
SHIRPA	forelimb digit size	females	0.0 %	1.0
SHIRPA	forelimb digit size	males	0.0 %	1.0
SHIRPA	forelimb digit size	both	0.0 %	1.0
SHIRPA	forelimb footpads	females	0.0 %	1.0
SHIRPA	forelimb footpads	males	0.0 %	1.0
SHIRPA	forelimb footpads	both	0.0 %	1.0
SHIRPA	forelimb nail length	females	0.0 %	1.0
SHIRPA	forelimb nail length	males	0.0 %	1.0
SHIRPA	forelimb nail length	both	0.0 %	1.0
SHIRPA	forelimb nail number	females	0.0 %	1.0
SHIRPA	forelimb nail number	males	0.0 %	1.0
SHIRPA	forelimb nail number	both	0.0 %	1.0
SHIRPA	forelimb nail position	females	0.0 %	1.0
SHIRPA	forelimb nail position	males	0.0 %	1.0
SHIRPA	forelimb nail position	both	0.0 %	1.0
SHIRPA	forelimb nail shape	females	0.0 %	1.0
SHIRPA	forelimb nail shape	males	0.0 %	1.0
SHIRPA	forelimb nail shape	both	0.0 %	1.0
SHIRPA	forelimbs position	females	0.0 %	1.0
SHIRPA	forelimbs position	males	0.0 %	1.0
SHIRPA	forelimbs position	both	0.0 %	1.0
SHIRPA	forelimbs shape	females	0.0 %	1.0
SHIRPA	forelimbs shape	males	0.0 %	1.0
SHIRPA	forelimbs shape	both	0.0 %	1.0
SHIRPA	forelimbs size	females	0.0 %	1.0
SHIRPA	forelimbs size	males	0.0 %	1.0
SHIRPA	forelimbs size	both	0.0 %	1.0
SHIRPA	forepaw position	females	0.0 %	1.0
SHIRPA	forepaw position	males	0.0 %	1.0
SHIRPA	forepaw position	both	0.0 %	1.0
SHIRPA	forepaw shape	females	0.0 %	1.0
SHIRPA	forepaw shape	males	0.0 %	1.0
SHIRPA	forepaw shape	both	0.0 %	1.0
SHIRPA	forepaw size	females	0.0 %	1.0
SHIRPA	forepaw size	males	0.0 %	1.0
SHIRPA	forepaw size	both	0.0 %	1.0
SHIRPA	gait (fluidity)	females	0.0 %	1.0
SHIRPA	gait (fluidity)	males	0.0 %	1.00
SHIRPA	gait (fluidity)	both	0.0 %	1.00
SHIRPA	genitalia morphology	females	0.0 %	1.00
SHIRPA	genitalia morphology	males	0.0 %	1.0
SHIRPA	genitalia morphology	both	0.0 %	1.00
SHIRPA	genitalia presence	females	0.0 %	1.0
SHIRPA	genitalia presence	males	0.0 %	1.0
SHIRPA	genitalia presence	both	0.0 %	1.0
SHIRPA	genitalia size	females	0.0 %	1.0
SHIRPA	genitalia size	males	0.0 %	1.0
SHIRPA	genitalia size	both	0.0 %	1.0
SHIRPA	head bobbing	females	0.0 %	1.0
SHIRPA	head bobbing	males	0.0 %	1.0
SHIRPA	head bobbing	both	0.0 %	1.0
SHIRPA	head morphology	females	0.0 %	1.0
SHIRPA	head morphology	males	0.0 %	1.00
SHIRPA	head morphology	both	0.0 %	1.0
SHIRPA	head size	females	0.0 %	1.0
SHIRPA	head size	males	0.0 %	1.0
SHIRPA	head size	both	0.0 %	1.00
SHIRPA	hindlimb digit number	females	1.0 %	1.00
SHIRPA	hindlimb digit number	males	0.0 %	1.0
SHIRPA	hindlimb digit number	both	0.0 %	1.00
SHIRPA	hindlimb digit position	females	0.0 %	1.0
SHIRPA	hindlimb digit position	males	0.0 %	1.0
SHIRPA	hindlimb digit position	both	0.0 %	1.0
SHIRPA	hindlimb digit shape	females	0.0 %	1.0
SHIRPA	hindlimb digit shape	males	0.0 %	1.0
SHIRPA	hindlimb digit shape	both	0.0 %	1.0
SHIRPA	hindlimb digit size	females	0.0 %	1.00
SHIRPA	hindlimb digit size	males	0.0 %	1.0
SHIRPA	hindlimb digit size	both	0.0 %	1.00
SHIRPA	hindlimb nail length	females	0.0 %	1.0
SHIRPA	hindlimb nail length	males	0.0 %	1.0
SHIRPA	hindlimb nail length	both	0.0 %	1.00
SHIRPA	hindlimb nail number	females	0.0 %	1.0
SHIRPA	hindlimb nail number	males	1.0 %	1.0
SHIRPA	hindlimb nail number	both	0.0 %	1.00
SHIRPA	hindlimb nail position	females	0.0 %	1.0
SHIRPA	hindlimb nail position	males	0.0 %	1.0
SHIRPA	hindlimb nail position	both	0.0 %	1.0
SHIRPA	hindlimb nail shape	females	0.0 %	1.0
SHIRPA	hindlimb nail shape	males	0.0 %	1.0
SHIRPA	hindlimb nail shape	both	0.0 %	1.0
SHIRPA	hindlimbs footpads	females	0.0 %	1.0
SHIRPA	hindlimbs footpads	males	0.0 %	1.0
SHIRPA	hindlimbs footpads	both	0.0 %	1.0
SHIRPA	hindlimbs position	females	0.0 %	1.0
SHIRPA	hindlimbs position	males	0.0 %	1.0
SHIRPA	hindlimbs position	both	0.0 %	1.0
SHIRPA	hindlimbs shape	females	0.0 %	1.0
SHIRPA	hindlimbs shape	males	0.0 %	1.0
SHIRPA	hindlimbs shape	both	0.0 %	1.0
SHIRPA	hindlimbs size	females	0.0 %	1.0
SHIRPA	hindlimbs size	males	0.0 %	1.0
SHIRPA	hindlimbs size	both	0.0 %	1.0
SHIRPA	hindpaw position	females	0.0 %	1.0
SHIRPA	hindpaw position	males	0.0 %	1.0
SHIRPA	hindpaw position	both	0.0 %	1.0
SHIRPA	hindpaw shape	females	0.0 %	1.0
SHIRPA	hindpaw shape	males	0.0 %	1.0
SHIRPA	hindpaw shape	both	0.0 %	1.0
SHIRPA	hindpaw size	females	0.0 %	1.0
SHIRPA	hindpaw size	males	0.0 %	1.0
SHIRPA	hindpaw size	both	0.0 %	1.0
SHIRPA	limb grasp	females	29.0 %	0.0280
SHIRPA	limb grasp	males	32.0 %	0.00854
SHIRPA	limb grasp	both	30.0 %	0.000648
SHIRPA	lower lip morphology	females	0.0 %	1.0
SHIRPA	lower lip morphology	males	0.0 %	1.0
SHIRPA	lower lip morphology	both	0.0 %	1.0
SHIRPA	lower teeth appearance	females	0.0 %	1.0
SHIRPA	lower teeth appearance	males	0.0 %	1.00
SHIRPA	lower teeth appearance	both	0.0 %	1.00
SHIRPA	mouth morphology	females	0.0 %	1.0
SHIRPA	mouth morphology	males	0.0 %	1.00
SHIRPA	mouth morphology	both	0.0 %	1.00
SHIRPA	salivation	females	0.0 %	1.0
SHIRPA	salivation	males	0.0 %	1.0
SHIRPA	salivation	both	0.0 %	1.0
SHIRPA	skin color back paws	females	0.0 %	1.0
SHIRPA	skin color back paws	males	0.0 %	1.0
SHIRPA	skin color back paws	both	0.0 %	1.0
SHIRPA	skin color ear	females	0.0 %	1.0
SHIRPA	skin color ear	males	0.0 %	1.0
SHIRPA	skin color ear	both	0.0 %	1.0
SHIRPA	skin color front paws	females	0.0 %	1.0
SHIRPA	skin color front paws	males	0.0 %	1.0
SHIRPA	skin color front paws	both	0.0 %	1.0
SHIRPA	skin color snout	females	0.0 %	1.0
SHIRPA	skin color snout	males	0.0 %	1.0
SHIRPA	skin color snout	both	0.0 %	1.0
SHIRPA	skin color tail	females	0.0 %	1.0
SHIRPA	skin color tail	males	0.0 %	1.0
SHIRPA	skin color tail	both	0.0 %	1.0
SHIRPA	skin color whole body	females	0.0 %	1.0
SHIRPA	skin color whole body	males	0.0 %	1.0
SHIRPA	skin color whole body	both	0.0 %	1.0
SHIRPA	skin texture back paw	females	0.0 %	1.0
SHIRPA	skin texture back paw	males	0.0 %	1.0
SHIRPA	skin texture back paw	both	0.0 %	1.0
SHIRPA	skin texture ear	females	0.0 %	1.0
SHIRPA	skin texture ear	males	0.0 %	1.0
SHIRPA	skin texture ear	both	0.0 %	1.0
SHIRPA	skin texture front paws	females	0.0 %	1.0
SHIRPA	skin texture front paws	males	0.0 %	1.0
SHIRPA	skin texture front paws	both	0.0 %	1.0
SHIRPA	skin texture snout	females	0.0 %	1.0
SHIRPA	skin texture snout	males	0.0 %	1.0
SHIRPA	skin texture snout	both	0.0 %	1.0
SHIRPA	skin texture tail	females	0.0 %	1.0
SHIRPA	skin texture tail	males	0.0 %	1.0
SHIRPA	skin texture tail	both	0.0 %	1.0
SHIRPA	skin texture whole body	females	0.0 %	1.0
SHIRPA	skin texture whole body	males	0.0 %	1.00
SHIRPA	skin texture whole body	both	0.0 %	1.00
SHIRPA	snout size	females	0.0 %	1.0
SHIRPA	snout size	males	1.0 %	1.0
SHIRPA	snout size	both	0.0 %	1.0
SHIRPA	startle response	females	0.0 %	1.00
SHIRPA	startle response	males	0.0 %	1.00
SHIRPA	startle response	both	0.0 %	1.00
SHIRPA	tail curvature	females	0.0 %	1.00
SHIRPA	tail curvature	males	0.0 %	1.0
SHIRPA	tail curvature	both	0.0 %	1.0
SHIRPA	tail elevation	females	1.0 %	1.00
SHIRPA	tail elevation	males	2.0 %	1.0
SHIRPA	tail elevation	both	1.0 %	1.0
SHIRPA	tail length	females	0.0 %	1.0
SHIRPA	tail length	males	0.0 %	1.0
SHIRPA	tail length	both	0.0 %	1.00
SHIRPA	tail morphology	females	0.0 %	1.00
SHIRPA	tail morphology	males	0.0 %	1.0
SHIRPA	tail morphology	both	0.0 %	1.00
SHIRPA	tail presence	females	0.0 %	1.0
SHIRPA	tail presence	males	0.0 %	1.0
SHIRPA	tail presence	both	0.0 %	1.0
SHIRPA	tail shape	females	0.0 %	1.0
SHIRPA	tail shape	males	0.0 %	1.0
SHIRPA	tail shape	both	0.0 %	1.00
SHIRPA	tail thickness	females	0.0 %	1.0
SHIRPA	tail thickness	males	0.0 %	1.0
SHIRPA	tail thickness	both	0.0 %	1.0
SHIRPA	teeth presence	females	0.0 %	1.0
SHIRPA	teeth presence	males	0.0 %	1.00
SHIRPA	teeth presence	both	0.0 %	1.00
SHIRPA	transfer arousal	females	12.0 %	0.0876
SHIRPA	transfer arousal	males	2.0 %	1.00
SHIRPA	transfer arousal	both	6.0 %	0.109
SHIRPA	tremor	females	0.0 %	1.0
SHIRPA	tremor	males	0.0 %	1.0
SHIRPA	tremor	both	0.0 %	1.00
SHIRPA	trunk curl	females	0.0 %	1.00
SHIRPA	trunk curl	males	0.0 %	1.0
SHIRPA	trunk curl	both	0.0 %	1.0
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	females	0.0 %	1.0
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	males	0.0 %	1.0
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	both	0.0 %	1.00
SHIRPA	upper lip morphology	females	0.0 %	1.0
SHIRPA	upper lip morphology	males	0.0 %	1.0
SHIRPA	upper lip morphology	both	0.0 %	1.0
SHIRPA	upper teeth appearance	females	0.0 %	1.0
SHIRPA	upper teeth appearance	males	0.0 %	1.0
SHIRPA	upper teeth appearance	both	0.0 %	1.00
SHIRPA	vibrissae appearance	females	2.0 %	1.0
SHIRPA	vibrissae appearance	males	1.0 %	1.0
SHIRPA	vibrissae appearance	both	1.0 %	1.0
SHIRPA	vibrissae presence	females	2.0 %	1.00
SHIRPA	vibrissae presence	males	1.0 %	1.0
SHIRPA	vibrissae presence	both	2.0 %	1.0
SHIRPA	vocalization	females	2.0 %	1.00
SHIRPA	vocalization	males	2.0 %	1.0
SHIRPA	vocalization	both	2.0 %	1.00

GENOTYPE CORRELATION PLOT

Correlate Ffar2^{tm1b(EUCOMM)Hmgu} -/- with genotype: