MPD: JaxKOMP-EAP genotype: Tmco3<sup>tm1b(KOMP)Wtsi</sup> -/-

JaxKOMP-EAP effect sizes: Tmco3^{tm1b(KOMP)Wtsi} -/- Gene Tmco3

MULTIPLE (NUMERIC) TRAIT PROFILE PLOT — Early Adult Phenotyping study (EAP)

In this plot, data points are the computed genotype effect size vs. C57BL/6NJ controls, for all measured numeric phenotypes in JaxKOMP-EAP

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Plot Options Group by Procedure Standard Error Show Effect Sizes RankZ

Significance Threshold p-Value Threshold Adjusted Unadjusted

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Procedure	JaxKOMP-EAP Trait	Trait Effect	Trait Effect SE	Trait Effect RankZ	Adjusted p-value	Unadjusted p-value

ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 6 kHz pip	0.45455	1.7234	-0.14747	0.947	0.809
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 12 kHz pip	-4.9644	5.3426	-1.0181	0.826	0.421
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 24 kHz pip	9.8345	5.2160	1.3736	0.533	0.156
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 30 kHz pip	-5.8615	16.422	-0.90231	0.898	0.745
body composition	body length	-0.30922	0.049304	-2.0157	0.0000220	9.63e-8
body composition	body weight (at time of DXA)	-2.9252	0.44941	-1.6033	0.00000293	3.83e-8
body composition	bone area, whole body scan, head excluded	-0.59929	0.16352	-1.8503	0.0133	0.000618
body composition	bone mineral content of whole body scan, head excluded	-0.0078800	0.011686	-0.31218	0.747	0.503
body composition	bone mineral content to body weight ratio	-0.00035414	0.00047330	-0.28222	0.696	0.458
body composition	bone mineral density of whole body scan, head excluded	0.0025067	0.00057099	2.4010	0.00367	0.0000620
body composition	fat tissue mass of whole body scan, head excluded	-0.11417	0.31369	-0.19788	0.860	0.717
body composition	fat tissue mass to body weight ratio	-0.011766	0.0089127	-0.50228	0.419	0.193
body composition	lean tissue mass of whole body scan, head excluded	0.64299	0.31005	1.0780	0.231	0.0435
body composition	lean tissue mass to body weight ratio	0.034976	0.0079209	1.6705	0.00463	0.0000554
body composition	percent fat, whole body scan, head excluded	-1.5351	0.86145	-0.72329	0.255	0.0809
body composition	ratio of soft-tissue attenuation coefficients	0.0017537	0.00096098	0.74310	0.245	0.0741
body composition	tissue area	-0.57421	0.17258	-1.5504	0.0317	0.00169
body composition	total tissue mass, whole body scan, head excluded	0.64832	0.19520	1.1027	0.0222	0.00172
clinical blood chemistry	alanine transaminase (plasma ALT)	-2.0239	11.968	-0.21780	0.961	0.867
clinical blood chemistry	albumin (plasma Alb)	-1.2000	0.44242	-1.4846	0.137	0.0127
clinical blood chemistry	alkaline phosphatase (plasma ALP)	3.6713	17.297	0.12430	0.923	0.834
clinical blood chemistry	aspartate transaminase (plasma AST)	-31.189	30.782	-1.3342	0.642	0.322
clinical blood chemistry	aspartate transaminase to alanine transaminase ratio (plasma AST:ALT)	-0.57354	0.40172	-1.6143	0.550	0.167
clinical blood chemistry	blood urea nitrogen (BUN)	-0.81250	1.1973	-0.35791	0.734	0.505
clinical blood chemistry	calcium (plasma Ca)	-0.21879	0.12058	-1.2233	0.257	0.0839
clinical blood chemistry	creatinine (plasma)	-0.017500	0.020693	-0.31247	0.643	0.408
clinical blood chemistry	glucose (plasma GLU, no fast)	-1.2667	11.713	0.24892	0.950	0.915
clinical blood chemistry	HDL cholesterol (plasma HDL)	-2.0933	2.3845	-0.77254	0.679	0.389
clinical blood chemistry	HDL cholesterol to total cholesterol ratio	-0.0052844	0.014029	-0.46535	0.902	0.710
clinical blood chemistry	phosphorus (plasma phosphate)	-0.19667	0.28876	-0.37712	0.755	0.503
clinical blood chemistry	total bilirubin (plasma TBIL)	-0.022667	0.010258	-1.4742	0.224	0.0378
clinical blood chemistry	total cholesterol (plasma CHOL, no fast)	1.1964	3.5214	-0.019195	0.902	0.737
clinical blood chemistry	total protein (plasma TP)	-0.37249	0.75671	-0.36023	0.808	0.627
clinical blood chemistry	triglyceride (plasma TG, no fast)	-20.544	7.2806	-0.86094	0.0925	0.00993
EKG	duration of PQ interval	-1.1464	0.98076	-1.0146	0.790	0.253
EKG	duration of PR interval	-1.2780	1.0647	-1.0991	0.807	0.241
EKG	duration of QRS interval	-0.056201	0.44087	-0.29435	0.990	0.900
EKG	duration of QT interval	-1.3188	0.78998	-1.0489	0.637	0.107
EKG	duration of QTC interval, calculated by dividing QT interval by square root of preceding RR interval	-0.59779	0.81813	-0.56460	0.913	0.472
EKG	duration of RR interval	-5.7769	2.1181	-2.2068	0.258	0.0115
EKG	duration of ST interval	-1.2758	0.72493	-1.0146	0.569	0.0902
EKG	heart rate coefficient of variation (signal intensity)	-3.4356	1.7605	-2.4072	0.774	0.0623
EKG	heart rate variability, mean of differences between sequential beats; beats per min	-23.537	12.744	-2.4454	0.771	0.0766
EKG	heart rate, beats per min	50.371	18.706	2.3395	0.231	0.0125
EKG	mean R amplitude, mean amplitude of signal measured from isoelectric line to peak of QRS	-0.41575	0.090279	-2.7247	0.0187	0.0000953
EKG	mean SR amplitude, mean amplitude of signal measured from signal minimum line to peak of QRS	-0.54530	0.11231	-2.7247	0.00764	0.0000492
EKG	number of signals	-3.5713	4.0913	-0.77404	0.832	0.391
EKG	proportion of number pairs of successive beat-to-beat intervals that exceed 50 ms	-11.600	5.2323	-1.9712	0.758	0.0360
EKG	QT dispersion, measured as inter-lead variability of QT intervals	-0.94341	2.8480	-0.24420	0.968	0.743
EKG	QTc dispersion, calculated as rate-corrected QT dispersion	1.4643	2.9738	0.39925	0.947	0.627
EKG	root mean square of successive differences of neighboring RR intervals	-3.7641	3.1628	-1.8390	0.843	0.245
glucose tolerance test	amount glucose injected	-6.0264	1.8510	-1.2888	0.0723	0.00238
glucose tolerance test	plasma glucose, 0min	-16.637	9.5272	-1.6204	0.240	0.0886
glucose tolerance test	plasma glucose, 15min	41.760	24.016	1.2349	0.355	0.0900
glucose tolerance test	plasma glucose, 30min	43.118	22.384	1.3694	0.299	0.0614
glucose tolerance test	plasma glucose, 60min	-58.010	22.911	-2.0713	0.156	0.0156
glucose tolerance test	plasma glucose, 120min	4.6497	12.427	0.18081	0.892	0.710
heart weight	heart weight, normalized to body weight	0.059537	0.14881	-0.23525	0.826	0.691
heart weight	heart weight, weight	1.5183	3.6946	-0.17864	0.817	0.683
hematology	basophil differential (percent of total WBC)	-0.024444	0.060466	-0.35167	0.911	0.690
hematology	calculated hemoglobin (cHGB)	-0.084444	0.16839	-0.54163	0.813	0.621
hematology	eosinophil differential (percent of total WBC)	-0.59444	0.25316	-1.4610	0.292	0.0283
hematology	hematocrit (HCT)	0.18333	0.57305	-0.18418	0.876	0.752
hematology	hemoglobin concentration distribution width (HDW)	0.061706	0.027391	1.5939	0.230	0.0351
hematology	large unstained cells (percent of total WBC)	0.098758	0.13468	0.64159	0.769	0.471
hematology	lymphocyte differential (percent of total WBC)	0.21000	0.82387	0.046486	0.909	0.801
hematology	mean corpuscular hemoglobin (CHr)	-0.040932	0.082206	-0.33450	0.810	0.623
hematology	mean platelet volume (MPV)	-0.10066	0.099947	-0.81915	0.553	0.325
hematology	mean RBC corpuscular hemoglobin (MCH)	0.11778	0.10501	0.43009	0.624	0.274
hematology	mean RBC corpuscular hemoglobin concentration (MCHC)	0.14333	0.33373	0.34651	0.877	0.672
hematology	mean RBC corpuscular volume (MCV)	0.62286	0.43077	1.0508	0.356	0.162
hematology	measured hemoglobin (mHGB)	0.13444	0.20259	0.095185	0.741	0.514
hematology	monocyte differential (percent of total WBC)	0.019646	0.18360	0.27543	0.969	0.916
hematology	neutrophil differential (percent of total WBC)	0.30889	0.70585	0.17862	0.824	0.666
hematology	platelet count (PLT; units per volume x 10³)	41.378	45.901	0.60653	0.708	0.377
hematology	RBC corpuscular distribution width (RDW)	0.44596	0.16829	1.3599	0.118	0.0150
hematology	RBC corpuscular hemoglobin concentration mean (CHCM)	-0.74529	0.34007	-1.7395	0.169	0.0398
hematology	red blood cell count (RBC; per volume x 10⁶)	0.0013333	0.11872	-0.33886	0.997	0.991
hematology	reticulocyte count (Retic; units per volume x 10⁹)	25.155	15.803	1.1040	0.498	0.126
hematology	reticulocyte differential (percent of total RBC)	0.30720	0.16344	1.3289	0.393	0.0735
hematology	white blood cell count (WBC; units per volume x 10³)	-1.6077	0.77372	-0.90116	0.164	0.0496
holeboard	number of hole pokes by individual hole number, 20 min test, 1	-3.2756	1.9284	-3.0007	0.705	0.231
holeboard	number of hole pokes by individual hole number, 20 min test, 2	-3.2868	1.9231	-3.2058	0.745	0.230
holeboard	number of hole pokes by individual hole number, 20 min test, 3	-1.6543	0.92329	-2.5961	0.733	0.215
holeboard	number of hole pokes by individual hole number, 20 min test, 4	-0.27097	1.1506	-0.16533	0.953	0.836
holeboard	number of hole pokes by individual hole number, 20 min test, 5	-0.12290	1.2221	-0.095515	0.985	0.929
holeboard	number of hole pokes by individual hole number, 20 min test, 6	-0.30000	0.29226	-0.81594	0.884	0.413
holeboard	number of hole pokes by individual hole number, 20 min test, 7	-2.0697	0.61337	-3.2054	0.716	0.0777
holeboard	number of hole pokes by individual hole number, 20 min test, 8	-0.16613	0.55579	-0.16875	0.963	0.793
holeboard	number of hole pokes by individual hole number, 20 min test, 9	-0.16947	1.3186	-0.22657	0.990	0.909
holeboard	number of hole pokes by individual hole number, 20 min test, 10	-1.1654	0.59237	-3.0001	0.746	0.188
holeboard	number of hole pokes by individual hole number, 20 min test, 11	-0.23871	0.36700	-0.64301	0.910	0.582
holeboard	number of hole pokes by individual hole number, 20 min test, 12	-0.39032	0.46449	-0.57901	0.856	0.489
holeboard	number of hole pokes by individual hole number, 20 min test, 13	-1.1919	0.89950	-1.0684	0.722	0.316
holeboard	number of hole pokes by individual hole number, 20 min test, 14	0.045161	0.53651	0.15411	0.986	0.941
holeboard	number of hole pokes by individual hole number, 20 min test, 15	-0.52903	0.53948	-0.74948	0.823	0.430
holeboard	number of hole pokes by individual hole number, 20 min test, 16	-0.46774	0.89587	-0.38914	0.911	0.654
holeboard	total number of hole pokes, 20 min test	-22.157	7.6962	-3.2060	0.353	0.102
light / dark	fecal boli count, 20 min test	0.55929	0.91256	0.67195	0.843	0.544
light / dark	latency to enter dark zone, 20 min test	56.063	91.506	0.88040	0.853	0.544
light / dark	number of transitions between light and dark zones, 20 min test	17.257	12.221	1.5380	0.484	0.167
light / dark	percentage of total time in dark zone, 20 min test	-6.3233	6.6694	-0.98265	0.687	0.349
light / dark	percentage of total time in light zone, 20 min test	6.3233	6.6694	0.97827	0.686	0.349
light / dark	time mobile in dark zone, 20 min test	-34.041	20.195	-1.8111	0.349	0.100
light / dark	time mobile in light zone, 20 min test	17.161	12.444	0.73074	0.427	0.176
light / dark	time spent in dark zone, 20 min test	-74.871	80.381	-0.90253	0.737	0.358
light / dark	time spent in light zone, 20 min test	74.871	80.381	0.90253	0.737	0.358
open field	average speed in center of arena, 20 min test	-0.30287	0.45932	-0.64404	0.793	0.514
open field	average speed in periphery of arena, 20 min test	0.14786	0.15798	0.084011	0.580	0.355
open field	distance traveled habituation ratio, 20 min test	-3.2151	8.1104	-0.22544	0.879	0.694
open field	distance traveled in center of arena, 20 min test	79.308	106.66	0.17203	0.691	0.462
open field	distance traveled in periphery of arena, 20 min test	42.775	155.85	-0.26557	0.892	0.785
open field	distance traveled slope, 20 min test	-6.3076	7.9409	-0.53382	0.721	0.432
open field	distance traveled, 20 min test, 1st 5min	63.285	75.127	0.14755	0.644	0.405
open field	distance traveled, 20 min test, 2nd 5min	83.107	51.062	0.43712	0.306	0.112
open field	distance traveled, 20 min test, 3rd 5min	-17.164	56.737	-0.63744	0.897	0.764
open field	distance traveled, 20 min test, 4th 5min	35.781	64.227	-0.047680	0.776	0.581
open field	number of clockwise revolution episodes, 20 min test	1.2536	1.2375	0.32961	0.674	0.317
open field	number of counter-clockwise revolution episodes, 20 min test	0.10137	1.0734	-0.37299	0.967	0.925
open field	number of fecal boli, 20 min test	2.2618	1.2790	1.8664	0.344	0.0850
open field	number of rears in 5 min bins, 20 min test, 1st 5min	-1.9217	2.2987	-0.71988	0.661	0.408
open field	number of rears in 5 min bins, 20 min test, 2nd 5min	-3.2463	2.3345	-1.1566	0.457	0.172
open field	number of rears in 5 min bins, 20 min test, 3rd 5min	-2.9515	2.3220	-0.98945	0.488	0.211
open field	number of rears in 5 min bins, 20 min test, 4th 5min	-4.2409	2.9815	-1.2537	0.431	0.163
open field	percentage of total time in center of arena, 20 min test	2.8461	2.0970	0.42093	0.495	0.183
open field	percentage of total time in center of arena, slope, 20 min test	-3.1825	1.2497	-1.4989	0.319	0.0151
open field	percentage of total time in center, habituation ratio, 20 min test	-3.0538	1.2735	-1.3815	0.332	0.0215
open field	percentage of total time in corners of arena, 20 min test	-0.17903	3.1292	0.28789	0.980	0.955
open field	percentage of total time in corners, habituation ratio, 20 min test	7.4482	2.1320	2.5186	0.0941	0.00123
open field	percentage of total time in corners, slope, 20 min test	7.2822	1.9232	2.5519	0.0865	0.000529
open field	permanence time in center of arena, 20 min test	34.159	25.164	0.42239	0.496	0.182
open field	permanence time in corners of arena, 20 min test	-2.1387	37.552	0.28789	0.980	0.955
open field	permanence time in periphery of arena, 20 min test	-34.160	25.167	-0.42239	0.496	0.182
open field	total distance traveled, 20 min test	164.04	207.09	0.015440	0.651	0.433
open field	total number of rears, 20 min test	-12.360	7.8505	-1.2106	0.336	0.123
open field	whole arena average speed, 20 min test	0.13740	0.17231	0.012755	0.646	0.430
open field	whole arena resting time, 20 min test	-20.279	19.756	-0.044992	0.517	0.311
open field	whole arena time spent mobile, 20 min test	20.397	19.760	0.29910	0.523	0.308
open field	whole arena time spent vertical, 20 min test	-15.356	9.1954	-1.2685	0.362	0.103
startle / PPI	average baseline movement during background noise	-2.6193	1.3935	-1.6866	0.565	0.0661
startle / PPI	average of each corrected maximum percent pre-pulse inhibition value	-0.047594	0.073978	-0.53520	0.794	0.523
startle / PPI	average of each corrected percent pre-pulse inhibition value	-0.036563	0.070650	-0.44256	0.841	0.607
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-10.096	8.0333	-1.0445	0.854	0.215
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	1.3222	6.9204	0.10598	0.954	0.849
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-2.2711	6.5853	-0.35553	0.902	0.732
startle / PPI	average startle response to full pulse (120 dB)	115.98	24.498	1.7811	0.000684	0.0000191
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	100.49	25.941	1.6528	0.00532	0.000324
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	93.168	22.213	1.6312	0.00251	0.000114
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	67.747	24.418	1.4402	0.0558	0.00785
startle / PPI	average startle response to pre-pulse, 74dB sound pressure level	-1.5544	1.0893	-1.0421	0.696	0.160
startle / PPI	average startle response to pre-pulse, 78dB sound pressure level	2.4512	1.3011	1.2439	0.544	0.0656
startle / PPI	average startle response to pre-pulse, 82dB sound pressure level	-0.75170	1.3201	-0.56783	0.870	0.572
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-0.095471	0.092195	-0.85528	0.869	0.306
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	0.029125	0.077515	0.16415	0.895	0.709
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-0.028654	0.075599	-0.41845	0.875	0.706
startle / PPI	corrected average startle response to full pulse (120 dB) minus average baseline movement during background noise	118.60	24.698	1.8164	0.000577	0.0000152
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 74dB sound pressure level	103.17	25.996	1.6866	0.00430	0.000241
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 78dB sound pressure level	92.387	22.225	1.6103	0.00275	0.000129
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 82dB sound pressure level	69.053	24.365	1.4894	0.0485	0.00670
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-0.084975	0.096690	-0.72870	0.860	0.384
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-0.0040864	0.080897	-0.11803	0.983	0.960
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-0.040840	0.083994	-0.48050	0.820	0.629
startle / PPI	corrected maximum startle response to full pulse (120 dB) minus maximum baseline movement during background noise	435.86	88.266	1.8237	0.000372	0.00000957
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 74dB sound pressure level	361.28	89.022	1.6365	0.00341	0.000181
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 78dB sound pressure level	285.21	103.91	1.4603	0.0533	0.00849
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 82dB sound pressure level	249.08	90.397	1.4809	0.0555	0.00826
startle / PPI	maximum baseline movement during background noise	-5.9067	3.4658	-1.5243	0.560	0.0947
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-8.9995	8.7817	-0.84322	0.888	0.310
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-1.4456	7.5534	-0.19815	0.942	0.849
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-3.7841	7.4523	-0.47942	0.817	0.614
startle / PPI	maximum startle response to full pulse (120 dB)	429.83	87.695	1.8091	0.000395	0.0000108
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	355.97	89.188	1.6259	0.00384	0.000224
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	293.97	104.35	1.4767	0.0470	0.00701
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	246.80	90.638	1.4685	0.0581	0.00899
startle / PPI	maximum startle response to pre-pulse, 74dB sound pressure level	-2.9474	2.6403	-0.81165	0.738	0.270
startle / PPI	maximum startle response to pre-pulse, 78dB sound pressure level	8.4626	2.8786	1.7164	0.257	0.00504
startle / PPI	maximum startle response to pre-pulse, 82dB sound pressure level	-1.0559	3.1509	-0.39462	0.904	0.739

MULTIPLE (CATEGORICAL) TRAIT PROFILE PLOT — Early Adult Phenotyping study (EAP)

In this plot, data points are the computed genotype effect % vs. C57BL/6NJ controls, for all measured categorical phenotypes in JaxKOMP-EAP

Dimensions Width: × Height: px

Plot Options Group by Procedure

Include Sexes Data Both Females Males

Significance Threshold p-Value Threshold

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Procedure	JaxKOMP-EAP Trait	Sex	Trait Effect	P-value

eye morphology	anterior chamber depth	females	1.0 %	1.0
eye morphology	anterior chamber depth	males	0.0 %	1.0
eye morphology	anterior chamber depth	both	1.0 %	1.0
eye morphology	bulging eye	females	1.0 %	1.0
eye morphology	bulging eye	males	0.0 %	1.0
eye morphology	bulging eye	both	1.0 %	1.00
eye morphology	cornea	females	4.0 %	1.0
eye morphology	cornea	males	2.0 %	1.0
eye morphology	cornea	both	3.0 %	1.00
eye morphology	cornea opacity	females	5.0 %	1.00
eye morphology	cornea opacity	males	1.0 %	1.0
eye morphology	cornea opacity	both	3.0 %	1.0
eye morphology	cornea vascularization	females	3.0 %	1.0
eye morphology	cornea vascularization	males	1.0 %	1.0
eye morphology	cornea vascularization	both	2.0 %	1.0
eye morphology	corneal deposits	females	2.0 %	1.0
eye morphology	corneal deposits	males	1.0 %	1.0
eye morphology	corneal deposits	both	1.0 %	1.00
eye morphology	corneal mineralization	females	2.0 %	1.0
eye morphology	corneal mineralization	males	1.0 %	1.0
eye morphology	corneal mineralization	both	1.0 %	1.0
eye morphology	corneal scleralization	females	3.0 %	1.00
eye morphology	corneal scleralization	males	1.0 %	1.0
eye morphology	corneal scleralization	both	2.0 %	1.0
eye morphology	corneal ulcer	females	1.0 %	1.0
eye morphology	corneal ulcer	males	1.0 %	1.0
eye morphology	corneal ulcer	both	1.0 %	1.0
eye morphology	eye closure	females	1.0 %	1.00
eye morphology	eye closure	males	0.0 %	1.0
eye morphology	eye closure	both	1.0 %	1.0
eye morphology	eye hemorrhage or blood presence	females	2.0 %	1.00
eye morphology	eye hemorrhage or blood presence	males	1.0 %	1.0
eye morphology	eye hemorrhage or blood presence	both	1.0 %	1.0
eye morphology	eyelid morphology	females	1.0 %	1.0
eye morphology	eyelid morphology	males	0.0 %	1.0
eye morphology	eyelid morphology	both	1.0 %	1.0
eye morphology	eyes (present, absent)	females	1.0 %	1.0
eye morphology	eyes (present, absent)	males	0.0 %	1.0
eye morphology	eyes (present, absent)	both	0.0 %	1.0
eye morphology	fusion between cornea and lens	females	4.0 %	1.00
eye morphology	fusion between cornea and lens	males	2.0 %	1.0
eye morphology	fusion between cornea and lens	both	3.0 %	1.0
eye morphology	iris pigmentation	females	2.0 %	1.0
eye morphology	iris pigmentation	males	1.0 %	1.0
eye morphology	iris pigmentation	both	2.0 %	1.0
eye morphology	iris transillumination	females	2.0 %	1.00
eye morphology	iris transillumination	males	1.0 %	1.00
eye morphology	iris transillumination	both	1.0 %	1.00
eye morphology	irispupil	females	4.0 %	1.0
eye morphology	irispupil	males	14.0 %	0.0108
eye morphology	irispupil	both	7.0 %	0.0271
eye morphology	lacrimation	females	3.0 %	1.0
eye morphology	lacrimation	males	2.0 %	1.0
eye morphology	lacrimation	both	3.0 %	1.0
eye morphology	lens	females	10.0 %	1.00
eye morphology	lens	males	8.0 %	1.00
eye morphology	lens	both	9.0 %	1.0
eye morphology	lens opacity	females	16.0 %	0.0616
eye morphology	lens opacity	males	6.0 %	1.00
eye morphology	lens opacity	both	6.0 %	0.144
eye morphology	narrow eye opening	females	2.0 %	1.0
eye morphology	narrow eye opening	males	1.0 %	1.0
eye morphology	narrow eye opening	both	1.0 %	1.00
eye morphology	optic disc	females	4.0 %	1.00
eye morphology	optic disc	males	2.0 %	1.00
eye morphology	optic disc	both	3.0 %	1.00
eye morphology	persistence of hyaloid vascular system	females	31.0 %	0.145
eye morphology	persistence of hyaloid vascular system	males	24.0 %	0.0290
eye morphology	persistence of hyaloid vascular system	both	24.0 %	0.0239
eye morphology	pupil dilation	females	2.0 %	1.0
eye morphology	pupil dilation	males	1.0 %	1.00
eye morphology	pupil dilation	both	2.0 %	1.0
eye morphology	pupil light response	females	2.0 %	1.00
eye morphology	pupil light response	males	1.0 %	1.0
eye morphology	pupil light response	both	2.0 %	1.0
eye morphology	pupil position	females	4.0 %	1.00
eye morphology	pupil position	males	14.0 %	0.0109
eye morphology	pupil position	both	7.0 %	0.0380
eye morphology	pupil shape	females	3.0 %	1.00
eye morphology	pupil shape	males	2.0 %	1.0
eye morphology	pupil shape	both	3.0 %	1.0
eye morphology	retina	females	40.0 %	0.00445
eye morphology	retina	males	13.0 %	0.356
eye morphology	retina	both	27.0 %	0.0225
eye morphology	retinal blood vessels	females	4.0 %	1.0
eye morphology	retinal blood vessels	males	2.0 %	1.0
eye morphology	retinal blood vessels	both	3.0 %	1.0
eye morphology	retinal blood vessels pattern	females	5.0 %	1.0
eye morphology	retinal blood vessels pattern	males	2.0 %	1.00
eye morphology	retinal blood vessels pattern	both	4.0 %	1.00
eye morphology	retinal blood vessels structure	females	4.0 %	1.00
eye morphology	retinal blood vessels structure	males	2.0 %	1.0
eye morphology	retinal blood vessels structure	both	3.0 %	1.0
eye morphology	retinal pigmentation	females	12.0 %	1.0
eye morphology	retinal pigmentation	males	14.0 %	1.0
eye morphology	retinal pigmentation	both	13.0 %	1.0
eye morphology	retinal structure	females	4.0 %	1.00
eye morphology	retinal structure	males	2.0 %	1.00
eye morphology	retinal structure	both	3.0 %	1.00
eye morphology	synechia	females	4.0 %	1.0
eye morphology	synechia	males	2.0 %	1.00
eye morphology	synechia	both	3.0 %	1.00
eye morphology	vitreous	females	4.0 %	1.00
eye morphology	vitreous	males	2.0 %	1.0
eye morphology	vitreous	both	3.0 %	1.0
SHIRPA	activity body position	females	1.0 %	1.0
SHIRPA	activity body position	males	2.0 %	1.0
SHIRPA	activity body position	both	1.0 %	1.00
SHIRPA	aggression	females	0.0 %	1.00
SHIRPA	aggression	males	1.0 %	1.0
SHIRPA	aggression	both	1.0 %	1.00
SHIRPA	body length	females	0.0 %	1.0
SHIRPA	body length	males	0.0 %	1.0
SHIRPA	body length	both	0.0 %	1.0
SHIRPA	body position	females	0.0 %	1.0
SHIRPA	body position	males	1.0 %	1.0
SHIRPA	body position	both	0.0 %	1.00
SHIRPA	body thickness	females	1.0 %	1.0
SHIRPA	body thickness	males	0.0 %	1.0
SHIRPA	body thickness	both	0.0 %	1.00
SHIRPA	coat color abdomen	females	3.0 %	1.00
SHIRPA	coat color abdomen	males	4.0 %	1.00
SHIRPA	coat color abdomen	both	4.0 %	1.00
SHIRPA	coat color back	females	0.0 %	1.0
SHIRPA	coat color back	males	0.0 %	1.0
SHIRPA	coat color back	both	0.0 %	1.00
SHIRPA	coat color head	females	0.0 %	1.0
SHIRPA	coat color head	males	0.0 %	1.0
SHIRPA	coat color head	both	0.0 %	1.0
SHIRPA	coat color pattern abdomen	females	1.0 %	1.0
SHIRPA	coat color pattern abdomen	males	1.0 %	1.0
SHIRPA	coat color pattern abdomen	both	1.0 %	1.00
SHIRPA	coat color pattern back	females	0.0 %	1.0
SHIRPA	coat color pattern back	males	0.0 %	1.0
SHIRPA	coat color pattern back	both	0.0 %	1.00
SHIRPA	coat color pattern head	females	0.0 %	1.0
SHIRPA	coat color pattern head	males	0.0 %	1.00
SHIRPA	coat color pattern head	both	0.0 %	1.0
SHIRPA	coat hair abdomen texture appearance	females	2.0 %	1.0
SHIRPA	coat hair abdomen texture appearance	males	2.0 %	1.0
SHIRPA	coat hair abdomen texture appearance	both	2.0 %	1.0
SHIRPA	coat hair back texture appearance	females	0.0 %	1.0
SHIRPA	coat hair back texture appearance	males	0.0 %	1.0
SHIRPA	coat hair back texture appearance	both	0.0 %	1.0
SHIRPA	coat hair distribution abdomen	females	0.0 %	1.0
SHIRPA	coat hair distribution abdomen	males	1.0 %	1.0
SHIRPA	coat hair distribution abdomen	both	1.0 %	1.0
SHIRPA	coat hair distribution back	females	0.0 %	1.0
SHIRPA	coat hair distribution back	males	0.0 %	1.0
SHIRPA	coat hair distribution back	both	0.0 %	1.00
SHIRPA	coat hair distribution head	females	1.0 %	1.00
SHIRPA	coat hair distribution head	males	1.0 %	1.0
SHIRPA	coat hair distribution head	both	1.0 %	1.0
SHIRPA	coat hair head texture appearance	females	0.0 %	1.00
SHIRPA	coat hair head texture appearance	males	0.0 %	1.0
SHIRPA	coat hair head texture appearance	both	0.0 %	1.0
SHIRPA	contact righting	females	5.0 %	1.0
SHIRPA	contact righting	males	5.0 %	1.00
SHIRPA	contact righting	both	5.0 %	1.00
SHIRPA	ear morphology	females	0.0 %	1.0
SHIRPA	ear morphology	males	0.0 %	1.0
SHIRPA	ear morphology	both	0.0 %	1.0
SHIRPA	fat distribution	females	0.0 %	1.0
SHIRPA	fat distribution	males	0.0 %	1.0
SHIRPA	fat distribution	both	0.0 %	1.0
SHIRPA	forelimb digit number	females	0.0 %	1.00
SHIRPA	forelimb digit number	males	0.0 %	1.0
SHIRPA	forelimb digit number	both	0.0 %	1.0
SHIRPA	forelimb digit position	females	0.0 %	1.0
SHIRPA	forelimb digit position	males	0.0 %	1.0
SHIRPA	forelimb digit position	both	0.0 %	1.0
SHIRPA	forelimb digit shape	females	0.0 %	1.0
SHIRPA	forelimb digit shape	males	0.0 %	1.0
SHIRPA	forelimb digit shape	both	0.0 %	1.0
SHIRPA	forelimb digit size	females	0.0 %	1.0
SHIRPA	forelimb digit size	males	0.0 %	1.0
SHIRPA	forelimb digit size	both	0.0 %	1.0
SHIRPA	forelimb footpads	females	0.0 %	1.0
SHIRPA	forelimb footpads	males	0.0 %	1.0
SHIRPA	forelimb footpads	both	0.0 %	1.0
SHIRPA	forelimb nail length	females	0.0 %	1.0
SHIRPA	forelimb nail length	males	0.0 %	1.0
SHIRPA	forelimb nail length	both	0.0 %	1.0
SHIRPA	forelimb nail number	females	0.0 %	1.0
SHIRPA	forelimb nail number	males	0.0 %	1.0
SHIRPA	forelimb nail number	both	0.0 %	1.0
SHIRPA	forelimb nail position	females	0.0 %	1.0
SHIRPA	forelimb nail position	males	0.0 %	1.0
SHIRPA	forelimb nail position	both	0.0 %	1.0
SHIRPA	forelimb nail shape	females	0.0 %	1.0
SHIRPA	forelimb nail shape	males	0.0 %	1.0
SHIRPA	forelimb nail shape	both	0.0 %	1.0
SHIRPA	forelimbs position	females	0.0 %	1.0
SHIRPA	forelimbs position	males	0.0 %	1.0
SHIRPA	forelimbs position	both	0.0 %	1.0
SHIRPA	forelimbs shape	females	0.0 %	1.0
SHIRPA	forelimbs shape	males	0.0 %	1.0
SHIRPA	forelimbs shape	both	0.0 %	1.0
SHIRPA	forelimbs size	females	0.0 %	1.0
SHIRPA	forelimbs size	males	0.0 %	1.00
SHIRPA	forelimbs size	both	0.0 %	1.0
SHIRPA	forepaw position	females	0.0 %	1.0
SHIRPA	forepaw position	males	0.0 %	1.0
SHIRPA	forepaw position	both	0.0 %	1.0
SHIRPA	forepaw shape	females	0.0 %	1.0
SHIRPA	forepaw shape	males	0.0 %	1.0
SHIRPA	forepaw shape	both	0.0 %	1.0
SHIRPA	forepaw size	females	0.0 %	1.0
SHIRPA	forepaw size	males	0.0 %	1.0
SHIRPA	forepaw size	both	0.0 %	1.0
SHIRPA	gait (fluidity)	females	0.0 %	1.0
SHIRPA	gait (fluidity)	males	0.0 %	1.0
SHIRPA	gait (fluidity)	both	0.0 %	1.0
SHIRPA	genitalia morphology	females	0.0 %	1.00
SHIRPA	genitalia morphology	males	0.0 %	1.0
SHIRPA	genitalia morphology	both	0.0 %	1.00
SHIRPA	genitalia presence	females	0.0 %	1.0
SHIRPA	genitalia presence	males	0.0 %	1.0
SHIRPA	genitalia presence	both	0.0 %	1.0
SHIRPA	genitalia size	females	0.0 %	1.0
SHIRPA	genitalia size	males	0.0 %	1.00
SHIRPA	genitalia size	both	0.0 %	1.00
SHIRPA	head bobbing	females	0.0 %	1.0
SHIRPA	head bobbing	males	0.0 %	1.0
SHIRPA	head bobbing	both	0.0 %	1.0
SHIRPA	head morphology	females	0.0 %	1.0
SHIRPA	head morphology	males	0.0 %	1.0
SHIRPA	head morphology	both	0.0 %	1.0
SHIRPA	head size	females	0.0 %	1.0
SHIRPA	head size	males	0.0 %	1.00
SHIRPA	head size	both	0.0 %	1.0
SHIRPA	hindlimb digit number	females	1.0 %	1.00
SHIRPA	hindlimb digit number	males	0.0 %	1.0
SHIRPA	hindlimb digit number	both	0.0 %	1.0
SHIRPA	hindlimb digit position	females	0.0 %	1.0
SHIRPA	hindlimb digit position	males	0.0 %	1.0
SHIRPA	hindlimb digit position	both	0.0 %	1.0
SHIRPA	hindlimb digit shape	females	0.0 %	1.0
SHIRPA	hindlimb digit shape	males	0.0 %	1.0
SHIRPA	hindlimb digit shape	both	0.0 %	1.00
SHIRPA	hindlimb digit size	females	0.0 %	1.00
SHIRPA	hindlimb digit size	males	0.0 %	1.00
SHIRPA	hindlimb digit size	both	0.0 %	1.00
SHIRPA	hindlimb nail length	females	0.0 %	1.0
SHIRPA	hindlimb nail length	males	0.0 %	1.00
SHIRPA	hindlimb nail length	both	0.0 %	1.0
SHIRPA	hindlimb nail number	females	0.0 %	1.0
SHIRPA	hindlimb nail number	males	1.0 %	1.00
SHIRPA	hindlimb nail number	both	0.0 %	1.0
SHIRPA	hindlimb nail position	females	0.0 %	1.0
SHIRPA	hindlimb nail position	males	0.0 %	1.0
SHIRPA	hindlimb nail position	both	0.0 %	1.0
SHIRPA	hindlimb nail shape	females	0.0 %	1.0
SHIRPA	hindlimb nail shape	males	0.0 %	1.0
SHIRPA	hindlimb nail shape	both	0.0 %	1.0
SHIRPA	hindlimbs footpads	females	0.0 %	1.0
SHIRPA	hindlimbs footpads	males	0.0 %	1.0
SHIRPA	hindlimbs footpads	both	0.0 %	1.0
SHIRPA	hindlimbs position	females	0.0 %	1.0
SHIRPA	hindlimbs position	males	0.0 %	1.0
SHIRPA	hindlimbs position	both	0.0 %	1.0
SHIRPA	hindlimbs shape	females	0.0 %	1.0
SHIRPA	hindlimbs shape	males	0.0 %	1.0
SHIRPA	hindlimbs shape	both	0.0 %	1.0
SHIRPA	hindlimbs size	females	0.0 %	1.0
SHIRPA	hindlimbs size	males	0.0 %	1.0
SHIRPA	hindlimbs size	both	0.0 %	1.0
SHIRPA	hindpaw position	females	0.0 %	1.0
SHIRPA	hindpaw position	males	0.0 %	1.0
SHIRPA	hindpaw position	both	0.0 %	1.0
SHIRPA	hindpaw shape	females	0.0 %	1.0
SHIRPA	hindpaw shape	males	0.0 %	1.0
SHIRPA	hindpaw shape	both	0.0 %	1.0
SHIRPA	hindpaw size	females	0.0 %	1.0
SHIRPA	hindpaw size	males	0.0 %	1.0
SHIRPA	hindpaw size	both	0.0 %	1.0
SHIRPA	limb grasp	females	9.0 %	1.00
SHIRPA	limb grasp	males	6.0 %	1.0
SHIRPA	limb grasp	both	7.0 %	0.620
SHIRPA	lower lip morphology	females	0.0 %	1.0
SHIRPA	lower lip morphology	males	0.0 %	1.0
SHIRPA	lower lip morphology	both	0.0 %	1.0
SHIRPA	lower teeth appearance	females	0.0 %	1.0
SHIRPA	lower teeth appearance	males	0.0 %	1.0
SHIRPA	lower teeth appearance	both	0.0 %	1.0
SHIRPA	mouth morphology	females	0.0 %	1.0
SHIRPA	mouth morphology	males	0.0 %	1.0
SHIRPA	mouth morphology	both	0.0 %	1.0
SHIRPA	salivation	females	0.0 %	1.0
SHIRPA	salivation	males	0.0 %	1.0
SHIRPA	salivation	both	0.0 %	1.0
SHIRPA	skin color back paws	females	0.0 %	1.0
SHIRPA	skin color back paws	males	0.0 %	1.0
SHIRPA	skin color back paws	both	0.0 %	1.0
SHIRPA	skin color ear	females	0.0 %	1.0
SHIRPA	skin color ear	males	0.0 %	1.0
SHIRPA	skin color ear	both	0.0 %	1.0
SHIRPA	skin color front paws	females	0.0 %	1.0
SHIRPA	skin color front paws	males	0.0 %	1.0
SHIRPA	skin color front paws	both	0.0 %	1.0
SHIRPA	skin color snout	females	0.0 %	1.0
SHIRPA	skin color snout	males	0.0 %	1.0
SHIRPA	skin color snout	both	0.0 %	1.0
SHIRPA	skin color tail	females	0.0 %	1.0
SHIRPA	skin color tail	males	0.0 %	1.0
SHIRPA	skin color tail	both	0.0 %	1.0
SHIRPA	skin color whole body	females	0.0 %	1.0
SHIRPA	skin color whole body	males	0.0 %	1.0
SHIRPA	skin color whole body	both	0.0 %	1.0
SHIRPA	skin texture back paw	females	0.0 %	1.0
SHIRPA	skin texture back paw	males	0.0 %	1.0
SHIRPA	skin texture back paw	both	0.0 %	1.0
SHIRPA	skin texture ear	females	0.0 %	1.0
SHIRPA	skin texture ear	males	0.0 %	1.0
SHIRPA	skin texture ear	both	0.0 %	1.0
SHIRPA	skin texture front paws	females	0.0 %	1.0
SHIRPA	skin texture front paws	males	0.0 %	1.0
SHIRPA	skin texture front paws	both	0.0 %	1.0
SHIRPA	skin texture snout	females	0.0 %	1.0
SHIRPA	skin texture snout	males	0.0 %	1.0
SHIRPA	skin texture snout	both	0.0 %	1.0
SHIRPA	skin texture tail	females	0.0 %	1.0
SHIRPA	skin texture tail	males	0.0 %	1.0
SHIRPA	skin texture tail	both	0.0 %	1.0
SHIRPA	skin texture whole body	females	0.0 %	1.0
SHIRPA	skin texture whole body	males	0.0 %	1.0
SHIRPA	skin texture whole body	both	0.0 %	1.00
SHIRPA	snout size	females	0.0 %	1.0
SHIRPA	snout size	males	1.0 %	1.0
SHIRPA	snout size	both	0.0 %	1.0
SHIRPA	startle response	females	0.0 %	1.00
SHIRPA	startle response	males	0.0 %	1.00
SHIRPA	startle response	both	0.0 %	1.0
SHIRPA	tail curvature	females	0.0 %	1.00
SHIRPA	tail curvature	males	0.0 %	1.0
SHIRPA	tail curvature	both	0.0 %	1.00
SHIRPA	tail elevation	females	1.0 %	1.00
SHIRPA	tail elevation	males	2.0 %	1.0
SHIRPA	tail elevation	both	1.0 %	1.0
SHIRPA	tail length	females	0.0 %	1.0
SHIRPA	tail length	males	0.0 %	1.00
SHIRPA	tail length	both	0.0 %	1.0
SHIRPA	tail morphology	females	0.0 %	1.00
SHIRPA	tail morphology	males	0.0 %	1.00
SHIRPA	tail morphology	both	0.0 %	1.00
SHIRPA	tail presence	females	0.0 %	1.0
SHIRPA	tail presence	males	0.0 %	1.0
SHIRPA	tail presence	both	0.0 %	1.0
SHIRPA	tail shape	females	0.0 %	1.0
SHIRPA	tail shape	males	0.0 %	1.0
SHIRPA	tail shape	both	0.0 %	1.0
SHIRPA	tail thickness	females	0.0 %	1.0
SHIRPA	tail thickness	males	0.0 %	1.0
SHIRPA	tail thickness	both	0.0 %	1.0
SHIRPA	teeth presence	females	0.0 %	1.0
SHIRPA	teeth presence	males	0.0 %	1.0
SHIRPA	teeth presence	both	0.0 %	1.0
SHIRPA	transfer arousal	females	1.0 %	1.0
SHIRPA	transfer arousal	males	2.0 %	1.0
SHIRPA	transfer arousal	both	1.0 %	1.0
SHIRPA	tremor	females	0.0 %	1.0
SHIRPA	tremor	males	0.0 %	1.0
SHIRPA	tremor	both	0.0 %	1.00
SHIRPA	trunk curl	females	0.0 %	1.00
SHIRPA	trunk curl	males	0.0 %	1.0
SHIRPA	trunk curl	both	0.0 %	1.00
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	females	0.0 %	1.0
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	males	0.0 %	1.0
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	both	0.0 %	1.0
SHIRPA	upper lip morphology	females	0.0 %	1.0
SHIRPA	upper lip morphology	males	0.0 %	1.0
SHIRPA	upper lip morphology	both	0.0 %	1.0
SHIRPA	upper teeth appearance	females	0.0 %	1.0
SHIRPA	upper teeth appearance	males	0.0 %	1.00
SHIRPA	upper teeth appearance	both	0.0 %	1.0
SHIRPA	vibrissae appearance	females	2.0 %	1.0
SHIRPA	vibrissae appearance	males	1.0 %	1.0
SHIRPA	vibrissae appearance	both	1.0 %	1.0
SHIRPA	vibrissae presence	females	2.0 %	1.00
SHIRPA	vibrissae presence	males	1.0 %	1.0
SHIRPA	vibrissae presence	both	2.0 %	1.0
SHIRPA	vocalization	females	2.0 %	1.00
SHIRPA	vocalization	males	2.0 %	1.0
SHIRPA	vocalization	both	2.0 %	1.0

GENOTYPE CORRELATION PLOT

Correlate Tmco3^{tm1b(KOMP)Wtsi} -/- with genotype: