MPD: JaxKOMP-EAP genotype: Ppip5k2<sup>tm1b(EUCOMM)Wtsi</sup> -/+

JaxKOMP-EAP effect sizes: Ppip5k2^{tm1b(EUCOMM)Wtsi} -/+ Gene Ppip5k2

MULTIPLE (NUMERIC) TRAIT PROFILE PLOT — Early Adult Phenotyping study (EAP)

Procedure	JaxKOMP-EAP Trait	Trait Effect	Trait Effect SE	Trait Effect RankZ	Adjusted p-value	Unadjusted p-value
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 6 kHz pip	0.68660	1.3749	-0.060542	0.886	0.624
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 12 kHz pip	2.4622	1.9517	0.58002	0.712	0.225
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 18 kHz pip	-3.2414	2.1598	-0.85998	0.509	0.153
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 24 kHz pip	1.0135	3.3070	0.037305	0.911	0.763
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 30 kHz pip	-0.62231	2.9630	-0.11380	0.937	0.836
body composition	body length	-0.058944	0.037023	-0.49702	0.370	0.116
body composition	body weight (at time of DXA)	-1.2658	0.49363	-0.79658	0.0668	0.0126
body composition	bone area, whole body scan, head excluded	-0.30181	0.13392	-0.97398	0.152	0.0275
body composition	bone mineral content of whole body scan, head excluded	-0.023713	0.0098358	-1.0755	0.124	0.0187
body composition	bone mineral content to body weight ratio	-0.0012405	0.00041216	-1.2897	0.0417	0.00370
body composition	bone mineral density of whole body scan, head excluded	-0.0010550	0.00046020	-1.0825	0.156	0.0251
body composition	fat tissue mass of whole body scan, head excluded	0.36907	0.29822	0.59923	0.463	0.220
body composition	fat tissue mass to body weight ratio	0.013670	0.010217	0.65745	0.411	0.185
body composition	lean tissue mass of whole body scan, head excluded	-0.010648	0.24635	-0.18537	0.992	0.966
body composition	lean tissue mass to body weight ratio	-0.0069211	0.0089931	-0.42574	0.681	0.444
body composition	percent fat, whole body scan, head excluded	1.2331	0.98152	0.64059	0.451	0.213
body composition	ratio of soft-tissue attenuation coefficients	-0.0013605	0.0010931	-0.65063	0.462	0.218
body composition	tissue area	0.045501	0.15162	0.33703	0.918	0.765
body composition	total tissue mass, whole body scan, head excluded	0.35132	0.20377	0.53036	0.274	0.0894
clinical blood chemistry	alanine transaminase (plasma ALT)	-8.3047	27.836	-0.71645	0.927	0.767
clinical blood chemistry	albumin (plasma Alb)	0.017249	0.57622	0.097110	0.993	0.976
clinical blood chemistry	alkaline phosphatase (plasma ALP)	2.8702	3.7106	-0.030470	0.679	0.445
clinical blood chemistry	aspartate transaminase (plasma AST)	-45.621	37.812	-1.7109	0.553	0.236
clinical blood chemistry	aspartate transaminase to alanine transaminase ratio (plasma AST:ALT)	-0.17445	0.40113	-0.55362	0.893	0.666
clinical blood chemistry	blood urea nitrogen (BUN)	-0.86835	1.4205	-0.39173	0.757	0.545
clinical blood chemistry	calcium (plasma Ca)	0.16457	0.095168	1.4285	0.273	0.0931
clinical blood chemistry	creatinine (plasma)	-0.041597	0.036405	-0.83119	0.519	0.262
clinical blood chemistry	glucose (plasma GLU, no fast)	-6.3566	11.295	0.057878	0.750	0.577
clinical blood chemistry	HDL cholesterol (plasma HDL)	1.9498	2.3935	0.13288	0.704	0.421
clinical blood chemistry	HDL cholesterol to total cholesterol ratio	-0.013160	0.010777	-0.86456	0.567	0.230
clinical blood chemistry	phosphorus (plasma phosphate)	0.44475	0.35139	0.61958	0.496	0.214
clinical blood chemistry	total bilirubin (plasma TBIL)	-0.0016461	0.011094	-0.11237	0.963	0.883
clinical blood chemistry	total cholesterol (plasma CHOL, no fast)	3.4333	2.9227	0.37928	0.566	0.249
clinical blood chemistry	total protein (plasma TP)	0.40527	0.64848	0.22749	0.753	0.536
clinical blood chemistry	triglyceride (plasma TG, no fast)	-3.3803	8.3980	0.032913	0.856	0.690
EKG	duration of PQ interval	-0.88301	1.0102	-0.77404	0.872	0.390
EKG	duration of PR interval	-0.81558	1.0558	-0.70001	0.887	0.447
EKG	duration of QRS interval	-0.44177	0.40264	-1.3406	0.885	0.283
EKG	duration of QT interval	-1.0458	0.91130	-0.84680	0.743	0.261
EKG	duration of QTC interval, calculated by dividing QT interval by square root of preceding RR interval	-0.52725	0.77953	-0.49503	0.920	0.505
EKG	duration of RR interval	-2.1599	2.1235	-0.84392	0.731	0.318
EKG	duration of ST interval	-0.95626	0.74306	-0.71814	0.714	0.209
EKG	heart rate coefficient of variation (signal intensity)	-0.25441	0.96571	-0.10295	0.968	0.794
EKG	heart rate variability, mean of differences between sequential beats; beats per min	-0.65496	6.5234	0.038294	0.980	0.921
EKG	heart rate, beats per min	26.746	17.026	1.3451	0.505	0.128
EKG	mean R amplitude, mean amplitude of signal measured from isoelectric line to peak of QRS	-0.040198	0.093038	-0.43811	0.892	0.669
EKG	mean SR amplitude, mean amplitude of signal measured from signal minimum line to peak of QRS	-0.048979	0.14030	-0.37892	0.908	0.730
EKG	number of signals	3.0018	4.1734	0.55752	0.872	0.478
EKG	proportion of number pairs of successive beat-to-beat intervals that exceed 50 ms	-10.307	5.7479	-1.7825	0.782	0.0846
EKG	QT dispersion, measured as inter-lead variability of QT intervals	-0.010687	2.2730	0.036277	0.999	0.996
EKG	QTc dispersion, calculated as rate-corrected QT dispersion	0.87563	2.0277	0.25876	0.952	0.669
EKG	root mean square of successive differences of neighboring RR intervals	-0.33583	0.42445	-0.068563	0.884	0.436
glucose tolerance test	amount glucose injected	-3.4552	2.6700	-0.62482	0.581	0.202
glucose tolerance test	plasma glucose, 0min	-2.4857	6.2302	-0.47432	0.836	0.692
glucose tolerance test	plasma glucose, 15min	-9.1373	24.665	-0.15158	0.898	0.713
glucose tolerance test	plasma glucose, 30min	19.770	22.690	0.71202	0.696	0.388
glucose tolerance test	plasma glucose, 60min	21.294	15.556	0.93576	0.492	0.178
glucose tolerance test	plasma glucose, 120min	-7.0849	7.7808	-0.62281	0.653	0.367
grip strength	body weight (at time of grip strength test)	-1.2753	0.43107	-0.90230	0.0258	0.00452
grip strength	forelimb and hindlimb grip strength (mean of trials), average	-24.640	8.2591	-1.4707	0.0311	0.00433
grip strength	forelimb and hindlimb grip strength (mean of trials), average normalized to bw	-1.0114	0.38050	-1.2323	0.0594	0.0102
grip strength	forelimb and hindlimb grip strength by trial, trial1	-16.436	8.3801	-0.83790	0.242	0.0552
grip strength	forelimb and hindlimb grip strength by trial, trial2	-29.983	11.460	-1.6465	0.0890	0.0116
grip strength	forelimb and hindlimb grip strength by trial, trial3	-26.787	11.058	-1.4292	0.121	0.0189
grip strength	forelimb grip strength (mean of trials), average	-6.5322	4.4541	-0.56449	0.378	0.149
grip strength	forelimb grip strength (mean of trials), average normalized to bw	-0.23611	0.19518	-0.37767	0.505	0.231
grip strength	forelimb grip strength by trial, trial1	-10.224	6.0794	-0.88634	0.372	0.0986
grip strength	forelimb grip strength by trial, trial2	-3.7940	6.7200	-0.21365	0.833	0.575
grip strength	forelimb grip strength by trial, trial3	-1.7128	5.9313	0.082874	0.912	0.774
heart weight	heart weight, normalized to body weight	-0.14508	0.12903	-1.0096	0.485	0.266
heart weight	heart weight, weight	-4.1047	3.2500	-0.92548	0.420	0.212
hematology	basophil differential (percent of total WBC)	0.15143	0.089234	1.7261	0.510	0.0991
hematology	calculated hemoglobin (cHGB)	0.22938	0.21053	0.42819	0.566	0.284
hematology	eosinophil differential (percent of total WBC)	0.020913	0.17261	0.13097	0.968	0.904
hematology	hematocrit (HCT)	0.60485	0.60725	0.30250	0.609	0.326
hematology	hemoglobin concentration distribution width (HDW)	0.027222	0.014758	0.73807	0.322	0.0738
hematology	large unstained cells (percent of total WBC)	0.073168	0.12356	0.46723	0.820	0.558
hematology	lymphocyte differential (percent of total WBC)	-0.36578	1.4319	-0.19810	0.909	0.800
hematology	mean corpuscular hemoglobin (CHr)	0.068520	0.048137	0.56920	0.381	0.164
hematology	mean platelet volume (MPV)	0.022089	0.11938	-0.019895	0.932	0.854
hematology	mean RBC corpuscular hemoglobin (MCH)	-0.045291	0.20917	-0.20969	0.930	0.830
hematology	mean RBC corpuscular hemoglobin concentration (MCHC)	0.36921	0.46466	0.76593	0.756	0.432
hematology	mean RBC corpuscular volume (MCV)	-0.14780	0.27905	-0.27259	0.785	0.600
hematology	measured hemoglobin (mHGB)	0.26024	0.22732	0.45032	0.571	0.260
hematology	monocyte differential (percent of total WBC)	-0.17619	0.43115	-0.36903	0.888	0.685
hematology	neutrophil differential (percent of total WBC)	-2.1232	2.1509	-0.88892	0.570	0.331
hematology	platelet count (PLT; units per volume x 10³)	89.215	72.004	1.1590	0.592	0.224
hematology	RBC corpuscular distribution width (RDW)	0.043300	0.12594	0.15618	0.864	0.733
hematology	RBC corpuscular hemoglobin concentration mean (CHCM)	0.20264	0.20581	0.51643	0.597	0.332
hematology	red blood cell count (RBC; per volume x 10⁶)	0.14552	0.14511	0.31720	0.592	0.323
hematology	reticulocyte count (Retic; units per volume x 10⁹)	8.5131	11.532	0.45852	0.794	0.465
hematology	reticulocyte differential (percent of total RBC)	0.049007	0.10694	0.42308	0.860	0.650
hematology	white blood cell count (WBC; units per volume x 10³)	0.46819	0.61740	0.50288	0.645	0.454
holeboard	number of hole pokes by individual hole number, 20 min test, 1	-0.80133	0.70788	-0.74229	0.723	0.263
holeboard	number of hole pokes by individual hole number, 20 min test, 2	-0.62626	0.49510	-0.82728	0.729	0.212
holeboard	number of hole pokes by individual hole number, 20 min test, 3	-0.17734	0.35487	-0.21345	0.918	0.619
holeboard	number of hole pokes by individual hole number, 20 min test, 4	-0.76660	0.63149	-0.70717	0.693	0.230
holeboard	number of hole pokes by individual hole number, 20 min test, 5	-0.78399	0.34231	-1.1790	0.402	0.0262
holeboard	number of hole pokes by individual hole number, 20 min test, 6	-0.33977	0.27240	-0.95582	0.834	0.218
holeboard	number of hole pokes by individual hole number, 20 min test, 7	-0.54405	0.30711	-1.5270	0.716	0.0825
holeboard	number of hole pokes by individual hole number, 20 min test, 8	-0.64973	0.52812	-0.95270	0.752	0.224
holeboard	number of hole pokes by individual hole number, 20 min test, 9	0.068907	0.31150	0.23698	0.972	0.826
holeboard	number of hole pokes by individual hole number, 20 min test, 10	-0.42507	0.31623	-1.2338	0.746	0.185
holeboard	number of hole pokes by individual hole number, 20 min test, 11	-1.1084	0.49529	-2.4366	0.562	0.0296
holeboard	number of hole pokes by individual hole number, 20 min test, 12	-0.60702	0.57298	-0.94521	0.735	0.294
holeboard	number of hole pokes by individual hole number, 20 min test, 13	-0.90392	0.80876	-0.81594	0.697	0.269
holeboard	number of hole pokes by individual hole number, 20 min test, 14	-0.67221	0.54040	-0.98828	0.665	0.220
holeboard	number of hole pokes by individual hole number, 20 min test, 15	-0.96264	0.56577	-1.4369	0.561	0.0955
holeboard	number of hole pokes by individual hole number, 20 min test, 16	-1.2826	0.93849	-1.1143	0.595	0.178
holeboard	total number of hole pokes, 20 min test	-11.236	4.6957	-1.4911	0.157	0.0208
light / dark	fecal boli count, 20 min test	0.16815	0.80594	0.19800	0.935	0.835
light / dark	latency to enter dark zone, 20 min test	-41.236	58.826	-0.87643	0.830	0.486
light / dark	number of transitions between light and dark zones, 20 min test	-4.4677	7.4368	-0.34902	0.794	0.550
light / dark	percentage of total time in dark zone, 20 min test	3.1197	4.5559	0.67704	0.783	0.496
light / dark	percentage of total time in light zone, 20 min test	-3.1197	4.5559	-0.67874	0.782	0.496
light / dark	time mobile in dark zone, 20 min test	11.723	15.330	0.59590	0.726	0.448
light / dark	time mobile in light zone, 20 min test	4.1830	11.206	0.027044	0.860	0.710
light / dark	time spent in dark zone, 20 min test	38.045	57.433	0.80893	0.832	0.510
light / dark	time spent in light zone, 20 min test	-38.045	57.433	-0.80893	0.832	0.510
open field	average speed in center of arena, 20 min test	0.22867	0.42299	0.32023	0.827	0.591
open field	average speed in periphery of arena, 20 min test	0.38924	0.15822	0.93818	0.0798	0.0166
open field	distance traveled habituation ratio, 20 min test	19.556	7.6252	1.5415	0.132	0.0127
open field	distance traveled in center of arena, 20 min test	124.78	83.143	0.46986	0.363	0.138
open field	distance traveled in periphery of arena, 20 min test	412.02	161.19	1.1106	0.0828	0.0130
open field	distance traveled slope, 20 min test	19.236	7.0878	1.5919	0.112	0.00857
open field	distance traveled, 20 min test, 1st 5min	7.2960	78.105	-0.28369	0.970	0.926
open field	distance traveled, 20 min test, 2nd 5min	152.26	55.333	1.1358	0.0576	0.00773
open field	distance traveled, 20 min test, 3rd 5min	199.43	57.949	1.5241	0.0152	0.00103
open field	distance traveled, 20 min test, 4th 5min	182.95	53.705	1.3575	0.0144	0.00115
open field	number of clockwise revolution episodes, 20 min test	1.0892	1.3933	0.22487	0.761	0.437
open field	number of counter-clockwise revolution episodes, 20 min test	3.9965	1.1557	1.5284	0.0254	0.000980
open field	number of fecal boli, 20 min test	0.12254	0.86378	0.37017	0.956	0.888
open field	number of rears in 5 min bins, 20 min test, 1st 5min	0.021859	1.8893	-0.20288	0.998	0.991
open field	number of rears in 5 min bins, 20 min test, 2nd 5min	5.5719	1.9542	1.0812	0.0646	0.00588
open field	number of rears in 5 min bins, 20 min test, 3rd 5min	5.9511	2.1094	1.0343	0.0674	0.00639
open field	number of rears in 5 min bins, 20 min test, 4th 5min	5.3317	2.4432	0.82717	0.186	0.0328
open field	percentage of total time in center of arena, 20 min test	0.16306	2.4537	-0.15298	0.985	0.947
open field	percentage of total time in center of arena, slope, 20 min test	-0.98713	1.2839	-0.40630	0.837	0.445
open field	percentage of total time in center, habituation ratio, 20 min test	-1.0168	1.3789	-0.42975	0.845	0.464
open field	percentage of total time in corners of arena, 20 min test	-2.7041	4.2335	-0.18021	0.784	0.525
open field	percentage of total time in corners, habituation ratio, 20 min test	-2.2163	2.1751	-1.3442	0.794	0.312
open field	percentage of total time in corners, slope, 20 min test	-2.6379	2.1040	-1.5731	0.701	0.215
open field	permanence time in center of arena, 20 min test	1.9591	29.443	-0.15162	0.985	0.947
open field	permanence time in corners of arena, 20 min test	-32.461	50.803	-0.18157	0.784	0.525
open field	permanence time in periphery of arena, 20 min test	-1.9228	29.450	0.15162	0.985	0.948
open field	total distance traveled, 20 min test	536.12	204.67	0.98073	0.0594	0.0110
open field	total number of rears, 20 min test	16.883	6.7142	0.81401	0.0919	0.0145
open field	whole arena average speed, 20 min test	0.44683	0.17067	0.98290	0.0594	0.0111
open field	whole arena resting time, 20 min test	-58.549	20.336	-0.99604	0.0350	0.00544
open field	whole arena time spent mobile, 20 min test	58.544	20.319	1.2023	0.0366	0.00541
open field	whole arena time spent vertical, 20 min test	11.100	6.3559	0.76811	0.336	0.0856
SHIRPA	locomotor activity (number of squares in the arena the mouse moves into with all four paws in first 30 s of test)	-1.2920	1.5552	-0.36060	0.689	0.410
startle / PPI	average baseline movement during background noise	0.71266	1.0495	0.54330	0.877	0.500
startle / PPI	average of each corrected maximum percent pre-pulse inhibition value	-0.14364	0.082274	-1.3833	0.396	0.0864
startle / PPI	average of each corrected percent pre-pulse inhibition value	-0.15075	0.077666	-1.5418	0.324	0.0574
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-15.877	9.4318	-1.5952	0.817	0.0980
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-12.822	6.9210	-1.3006	0.391	0.0693
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-7.8751	5.3498	-0.84122	0.421	0.147
startle / PPI	average startle response to full pulse (120 dB)	-61.713	28.141	-0.88184	0.144	0.0326
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-42.558	26.982	-0.61117	0.319	0.120
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-41.268	24.985	-0.63157	0.285	0.104
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-21.083	21.658	-0.33175	0.561	0.335
startle / PPI	average startle response to pre-pulse, 74dB sound pressure level	-0.45313	1.6388	-0.26871	0.968	0.783
startle / PPI	average startle response to pre-pulse, 78dB sound pressure level	-1.7334	1.0207	-1.1967	0.591	0.0951
startle / PPI	average startle response to pre-pulse, 82dB sound pressure level	2.9589	1.0480	1.0397	0.183	0.00664
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-0.26356	0.13415	-1.9969	0.744	0.0545
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-0.17080	0.080010	-1.4973	0.268	0.0373
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-0.015102	0.062957	-0.30172	0.922	0.811
startle / PPI	corrected average startle response to full pulse (120 dB) minus average baseline movement during background noise	-62.425	28.382	-0.88806	0.139	0.0321
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 74dB sound pressure level	-42.105	27.507	-0.58603	0.331	0.132
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 78dB sound pressure level	-39.508	25.041	-0.60780	0.309	0.120
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 82dB sound pressure level	-23.160	21.715	-0.36450	0.508	0.291
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-0.26627	0.13776	-1.9387	0.710	0.0584
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-0.16503	0.084949	-1.3614	0.315	0.0572
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	0.0019361	0.066387	-0.17330	0.991	0.977
startle / PPI	corrected maximum startle response to full pulse (120 dB) minus maximum baseline movement during background noise	-308.29	108.69	-1.2624	0.0464	0.00641
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 74dB sound pressure level	-158.53	102.95	-0.63157	0.330	0.129
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 78dB sound pressure level	-161.48	94.621	-0.67493	0.262	0.0936
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 82dB sound pressure level	-97.221	80.840	-0.41744	0.447	0.234
startle / PPI	maximum baseline movement during background noise	1.9458	2.7977	0.62986	0.853	0.490
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-17.769	10.687	-1.6103	0.781	0.102
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-12.700	7.6671	-1.1630	0.434	0.103
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-4.8136	5.9317	-0.57773	0.695	0.421
startle / PPI	maximum startle response to full pulse (120 dB)	-305.03	108.42	-1.2409	0.0482	0.00682
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-160.27	102.09	-0.64186	0.320	0.122
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-166.92	94.567	-0.69263	0.239	0.0832
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-91.830	80.958	-0.40524	0.483	0.262
startle / PPI	maximum startle response to pre-pulse, 74dB sound pressure level	-1.7412	3.8906	-0.45287	0.925	0.656
startle / PPI	maximum startle response to pre-pulse, 78dB sound pressure level	-4.9689	2.2877	-1.3305	0.459	0.0342
startle / PPI	maximum startle response to pre-pulse, 82dB sound pressure level	7.7204	2.6950	1.0349	0.133	0.00593

MULTIPLE (CATEGORICAL) TRAIT PROFILE PLOT — Early Adult Phenotyping study (EAP)

Procedure	JaxKOMP-EAP Trait	Sex	Trait Effect	P-value
eye morphology	anterior chamber depth	females	1.0 %	1.0
eye morphology	anterior chamber depth	males	0.0 %	1.0
eye morphology	anterior chamber depth	both	1.0 %	1.0
eye morphology	bulging eye	females	1.0 %	1.0
eye morphology	bulging eye	males	0.0 %	1.0
eye morphology	bulging eye	both	1.0 %	1.00
eye morphology	cornea	females	4.0 %	1.0
eye morphology	cornea	males	2.0 %	1.0
eye morphology	cornea	both	3.0 %	1.00
eye morphology	cornea opacity	females	5.0 %	1.00
eye morphology	cornea opacity	males	1.0 %	1.0
eye morphology	cornea opacity	both	3.0 %	1.0
eye morphology	cornea vascularization	females	3.0 %	1.0
eye morphology	cornea vascularization	males	1.0 %	1.0
eye morphology	cornea vascularization	both	2.0 %	1.0
eye morphology	corneal deposits	females	2.0 %	1.0
eye morphology	corneal deposits	males	1.0 %	1.0
eye morphology	corneal deposits	both	1.0 %	1.00
eye morphology	corneal mineralization	females	2.0 %	1.0
eye morphology	corneal mineralization	males	1.0 %	1.0
eye morphology	corneal mineralization	both	1.0 %	1.00
eye morphology	corneal scleralization	females	3.0 %	1.00
eye morphology	corneal scleralization	males	1.0 %	1.0
eye morphology	corneal scleralization	both	2.0 %	1.0
eye morphology	corneal ulcer	females	1.0 %	1.0
eye morphology	corneal ulcer	males	1.0 %	1.0
eye morphology	corneal ulcer	both	1.0 %	1.00
eye morphology	eye closure	females	1.0 %	1.00
eye morphology	eye closure	males	0.0 %	1.0
eye morphology	eye closure	both	1.0 %	1.00
eye morphology	eye hemorrhage or blood presence	females	2.0 %	1.00
eye morphology	eye hemorrhage or blood presence	males	1.0 %	1.0
eye morphology	eye hemorrhage or blood presence	both	1.0 %	1.0
eye morphology	eyelid morphology	females	1.0 %	1.0
eye morphology	eyelid morphology	males	0.0 %	1.0
eye morphology	eyelid morphology	both	1.0 %	1.00
eye morphology	eyes (present, absent)	females	1.0 %	1.0
eye morphology	eyes (present, absent)	males	0.0 %	1.0
eye morphology	eyes (present, absent)	both	0.0 %	1.00
eye morphology	fusion between cornea and lens	females	4.0 %	1.00
eye morphology	fusion between cornea and lens	males	2.0 %	1.0
eye morphology	fusion between cornea and lens	both	3.0 %	1.0
eye morphology	iris pigmentation	females	2.0 %	1.0
eye morphology	iris pigmentation	males	1.0 %	1.0
eye morphology	iris pigmentation	both	2.0 %	1.0
eye morphology	iris transillumination	females	2.0 %	1.00
eye morphology	iris transillumination	males	1.0 %	1.00
eye morphology	iris transillumination	both	1.0 %	1.00
eye morphology	irispupil	females	4.0 %	1.00
eye morphology	irispupil	males	3.0 %	1.0
eye morphology	irispupil	both	3.0 %	1.0
eye morphology	lacrimation	females	3.0 %	1.0
eye morphology	lacrimation	males	2.0 %	1.00
eye morphology	lacrimation	both	3.0 %	1.00
eye morphology	lens	females	10.0 %	1.00
eye morphology	lens	males	8.0 %	1.00
eye morphology	lens	both	9.0 %	1.00
eye morphology	lens opacity	females	9.0 %	1.0
eye morphology	lens opacity	males	6.0 %	1.00
eye morphology	lens opacity	both	7.0 %	1.00
eye morphology	narrow eye opening	females	2.0 %	1.0
eye morphology	narrow eye opening	males	1.0 %	1.0
eye morphology	narrow eye opening	both	1.0 %	1.00
eye morphology	optic disc	females	4.0 %	1.00
eye morphology	optic disc	males	2.0 %	1.00
eye morphology	optic disc	both	3.0 %	1.00
eye morphology	persistence of hyaloid vascular system	females	6.0 %	0.690
eye morphology	persistence of hyaloid vascular system	males	5.0 %	1.0
eye morphology	persistence of hyaloid vascular system	both	3.0 %	0.745
eye morphology	pupil dilation	females	2.0 %	1.0
eye morphology	pupil dilation	males	1.0 %	1.00
eye morphology	pupil dilation	both	2.0 %	1.00
eye morphology	pupil light response	females	2.0 %	1.00
eye morphology	pupil light response	males	1.0 %	1.0
eye morphology	pupil light response	both	2.0 %	1.0
eye morphology	pupil position	females	4.0 %	1.00
eye morphology	pupil position	males	3.0 %	1.0
eye morphology	pupil position	both	4.0 %	1.0
eye morphology	pupil shape	females	3.0 %	1.00
eye morphology	pupil shape	males	2.0 %	1.0
eye morphology	pupil shape	both	3.0 %	1.0
eye morphology	retina	females	10.0 %	1.0
eye morphology	retina	males	16.0 %	1.0
eye morphology	retina	both	13.0 %	1.00
eye morphology	retinal blood vessels	females	4.0 %	1.0
eye morphology	retinal blood vessels	males	2.0 %	1.0
eye morphology	retinal blood vessels	both	3.0 %	1.00
eye morphology	retinal blood vessels pattern	females	5.0 %	1.0
eye morphology	retinal blood vessels pattern	males	2.0 %	1.00
eye morphology	retinal blood vessels pattern	both	4.0 %	1.00
eye morphology	retinal blood vessels structure	females	4.0 %	1.00
eye morphology	retinal blood vessels structure	males	2.0 %	1.0
eye morphology	retinal blood vessels structure	both	3.0 %	1.0
eye morphology	retinal pigmentation	females	12.0 %	1.0
eye morphology	retinal pigmentation	males	14.0 %	1.0
eye morphology	retinal pigmentation	both	13.0 %	1.00
eye morphology	retinal structure	females	4.0 %	1.00
eye morphology	retinal structure	males	2.0 %	1.00
eye morphology	retinal structure	both	3.0 %	1.00
eye morphology	synechia	females	4.0 %	1.0
eye morphology	synechia	males	2.0 %	1.00
eye morphology	synechia	both	3.0 %	1.00
eye morphology	vitreous	females	4.0 %	1.00
eye morphology	vitreous	males	2.0 %	1.0
eye morphology	vitreous	both	3.0 %	1.0
SHIRPA	activity body position	females	1.0 %	1.0
SHIRPA	activity body position	males	2.0 %	1.0
SHIRPA	activity body position	both	1.0 %	1.00
SHIRPA	aggression	females	0.0 %	1.00
SHIRPA	aggression	males	1.0 %	1.0
SHIRPA	aggression	both	1.0 %	1.0
SHIRPA	body length	females	0.0 %	1.0
SHIRPA	body length	males	0.0 %	1.00
SHIRPA	body length	both	0.0 %	1.0
SHIRPA	body position	females	0.0 %	1.0
SHIRPA	body position	males	1.0 %	1.0
SHIRPA	body position	both	0.0 %	1.0
SHIRPA	body thickness	females	1.0 %	1.00
SHIRPA	body thickness	males	0.0 %	1.0
SHIRPA	body thickness	both	0.0 %	1.00
SHIRPA	coat color abdomen	females	3.0 %	1.0
SHIRPA	coat color abdomen	males	4.0 %	1.0
SHIRPA	coat color abdomen	both	4.0 %	1.0
SHIRPA	coat color back	females	0.0 %	1.00
SHIRPA	coat color back	males	0.0 %	1.00
SHIRPA	coat color back	both	0.0 %	1.00
SHIRPA	coat color head	females	0.0 %	1.00
SHIRPA	coat color head	males	0.0 %	1.00
SHIRPA	coat color head	both	0.0 %	1.0
SHIRPA	coat color pattern abdomen	females	1.0 %	1.0
SHIRPA	coat color pattern abdomen	males	12.0 %	0.0550
SHIRPA	coat color pattern abdomen	both	5.0 %	0.113
SHIRPA	coat color pattern back	females	0.0 %	1.0
SHIRPA	coat color pattern back	males	0.0 %	1.00
SHIRPA	coat color pattern back	both	0.0 %	1.0
SHIRPA	coat color pattern head	females	0.0 %	1.0
SHIRPA	coat color pattern head	males	0.0 %	1.0
SHIRPA	coat color pattern head	both	0.0 %	1.0
SHIRPA	coat hair abdomen texture appearance	females	2.0 %	1.00
SHIRPA	coat hair abdomen texture appearance	males	2.0 %	1.0
SHIRPA	coat hair abdomen texture appearance	both	2.0 %	1.0
SHIRPA	coat hair back texture appearance	females	0.0 %	1.00
SHIRPA	coat hair back texture appearance	males	0.0 %	1.0
SHIRPA	coat hair back texture appearance	both	0.0 %	1.0
SHIRPA	coat hair distribution abdomen	females	0.0 %	1.0
SHIRPA	coat hair distribution abdomen	males	1.0 %	1.00
SHIRPA	coat hair distribution abdomen	both	1.0 %	1.0
SHIRPA	coat hair distribution back	females	0.0 %	1.0
SHIRPA	coat hair distribution back	males	0.0 %	1.0
SHIRPA	coat hair distribution back	both	0.0 %	1.00
SHIRPA	coat hair distribution head	females	1.0 %	1.00
SHIRPA	coat hair distribution head	males	1.0 %	1.0
SHIRPA	coat hair distribution head	both	1.0 %	1.0
SHIRPA	coat hair head texture appearance	females	0.0 %	1.00
SHIRPA	coat hair head texture appearance	males	0.0 %	1.0
SHIRPA	coat hair head texture appearance	both	0.0 %	1.0
SHIRPA	contact righting	females	5.0 %	1.0
SHIRPA	contact righting	males	5.0 %	1.00
SHIRPA	contact righting	both	5.0 %	0.624
SHIRPA	ear morphology	females	0.0 %	1.0
SHIRPA	ear morphology	males	0.0 %	1.0
SHIRPA	ear morphology	both	0.0 %	1.0
SHIRPA	fat distribution	females	0.0 %	1.00
SHIRPA	fat distribution	males	0.0 %	1.0
SHIRPA	fat distribution	both	0.0 %	1.0
SHIRPA	forelimb digit number	females	0.0 %	1.00
SHIRPA	forelimb digit number	males	0.0 %	1.0
SHIRPA	forelimb digit number	both	0.0 %	1.0
SHIRPA	forelimb digit position	females	0.0 %	1.0
SHIRPA	forelimb digit position	males	0.0 %	1.0
SHIRPA	forelimb digit position	both	0.0 %	1.0
SHIRPA	forelimb digit shape	females	0.0 %	1.0
SHIRPA	forelimb digit shape	males	0.0 %	1.0
SHIRPA	forelimb digit shape	both	0.0 %	1.00
SHIRPA	forelimb digit size	females	0.0 %	1.0
SHIRPA	forelimb digit size	males	0.0 %	1.0
SHIRPA	forelimb digit size	both	0.0 %	1.00
SHIRPA	forelimb footpads	females	0.0 %	1.00
SHIRPA	forelimb footpads	males	0.0 %	1.0
SHIRPA	forelimb footpads	both	0.0 %	1.00
SHIRPA	forelimb nail length	females	0.0 %	1.0
SHIRPA	forelimb nail length	males	0.0 %	1.0
SHIRPA	forelimb nail length	both	0.0 %	1.0
SHIRPA	forelimb nail number	females	0.0 %	1.0
SHIRPA	forelimb nail number	males	0.0 %	1.0
SHIRPA	forelimb nail number	both	0.0 %	1.00
SHIRPA	forelimb nail position	females	0.0 %	1.0
SHIRPA	forelimb nail position	males	0.0 %	1.0
SHIRPA	forelimb nail position	both	0.0 %	1.0
SHIRPA	forelimb nail shape	females	0.0 %	1.0
SHIRPA	forelimb nail shape	males	0.0 %	1.0
SHIRPA	forelimb nail shape	both	0.0 %	1.0
SHIRPA	forelimbs position	females	0.0 %	1.0
SHIRPA	forelimbs position	males	0.0 %	1.0
SHIRPA	forelimbs position	both	0.0 %	1.0
SHIRPA	forelimbs shape	females	0.0 %	1.0
SHIRPA	forelimbs shape	males	0.0 %	1.0
SHIRPA	forelimbs shape	both	0.0 %	1.0
SHIRPA	forelimbs size	females	0.0 %	1.0
SHIRPA	forelimbs size	males	0.0 %	1.0
SHIRPA	forelimbs size	both	0.0 %	1.0
SHIRPA	forepaw position	females	0.0 %	1.0
SHIRPA	forepaw position	males	0.0 %	1.0
SHIRPA	forepaw position	both	0.0 %	1.0
SHIRPA	forepaw shape	females	0.0 %	1.0
SHIRPA	forepaw shape	males	0.0 %	1.0
SHIRPA	forepaw shape	both	0.0 %	1.0
SHIRPA	forepaw size	females	0.0 %	1.0
SHIRPA	forepaw size	males	0.0 %	1.0
SHIRPA	forepaw size	both	0.0 %	1.0
SHIRPA	gait (fluidity)	females	0.0 %	1.0
SHIRPA	gait (fluidity)	males	0.0 %	1.00
SHIRPA	gait (fluidity)	both	0.0 %	1.0
SHIRPA	genitalia morphology	females	0.0 %	1.00
SHIRPA	genitalia morphology	males	0.0 %	1.0
SHIRPA	genitalia morphology	both	0.0 %	1.0
SHIRPA	genitalia presence	females	0.0 %	1.00
SHIRPA	genitalia presence	males	0.0 %	1.0
SHIRPA	genitalia presence	both	0.0 %	1.00
SHIRPA	genitalia size	females	0.0 %	1.0
SHIRPA	genitalia size	males	0.0 %	1.0
SHIRPA	genitalia size	both	0.0 %	1.00
SHIRPA	head bobbing	females	0.0 %	1.0
SHIRPA	head bobbing	males	0.0 %	1.0
SHIRPA	head bobbing	both	0.0 %	1.00
SHIRPA	head morphology	females	0.0 %	1.0
SHIRPA	head morphology	males	0.0 %	1.00
SHIRPA	head morphology	both	0.0 %	1.0
SHIRPA	head size	females	0.0 %	1.0
SHIRPA	head size	males	0.0 %	1.0
SHIRPA	head size	both	0.0 %	1.0
SHIRPA	hindlimb digit number	females	1.0 %	1.00
SHIRPA	hindlimb digit number	males	0.0 %	1.0
SHIRPA	hindlimb digit number	both	0.0 %	1.0
SHIRPA	hindlimb digit position	females	0.0 %	1.00
SHIRPA	hindlimb digit position	males	0.0 %	1.0
SHIRPA	hindlimb digit position	both	0.0 %	1.00
SHIRPA	hindlimb digit shape	females	0.0 %	1.0
SHIRPA	hindlimb digit shape	males	0.0 %	1.0
SHIRPA	hindlimb digit shape	both	0.0 %	1.00
SHIRPA	hindlimb digit size	females	0.0 %	1.00
SHIRPA	hindlimb digit size	males	0.0 %	1.0
SHIRPA	hindlimb digit size	both	0.0 %	1.0
SHIRPA	hindlimb nail length	females	0.0 %	1.0
SHIRPA	hindlimb nail length	males	0.0 %	1.0
SHIRPA	hindlimb nail length	both	0.0 %	1.0
SHIRPA	hindlimb nail number	females	0.0 %	1.0
SHIRPA	hindlimb nail number	males	1.0 %	1.0
SHIRPA	hindlimb nail number	both	0.0 %	1.0
SHIRPA	hindlimb nail position	females	0.0 %	1.0
SHIRPA	hindlimb nail position	males	0.0 %	1.0
SHIRPA	hindlimb nail position	both	0.0 %	1.0
SHIRPA	hindlimb nail shape	females	0.0 %	1.0
SHIRPA	hindlimb nail shape	males	0.0 %	1.0
SHIRPA	hindlimb nail shape	both	0.0 %	1.0
SHIRPA	hindlimbs footpads	females	0.0 %	1.00
SHIRPA	hindlimbs footpads	males	0.0 %	1.0
SHIRPA	hindlimbs footpads	both	0.0 %	1.00
SHIRPA	hindlimbs position	females	0.0 %	1.0
SHIRPA	hindlimbs position	males	0.0 %	1.0
SHIRPA	hindlimbs position	both	0.0 %	1.0
SHIRPA	hindlimbs shape	females	0.0 %	1.0
SHIRPA	hindlimbs shape	males	0.0 %	1.0
SHIRPA	hindlimbs shape	both	0.0 %	1.0
SHIRPA	hindlimbs size	females	0.0 %	1.0
SHIRPA	hindlimbs size	males	0.0 %	1.0
SHIRPA	hindlimbs size	both	0.0 %	1.0
SHIRPA	hindpaw position	females	0.0 %	1.0
SHIRPA	hindpaw position	males	0.0 %	1.0
SHIRPA	hindpaw position	both	0.0 %	1.00
SHIRPA	hindpaw shape	females	0.0 %	1.00
SHIRPA	hindpaw shape	males	0.0 %	1.0
SHIRPA	hindpaw shape	both	0.0 %	1.00
SHIRPA	hindpaw size	females	0.0 %	1.00
SHIRPA	hindpaw size	males	0.0 %	1.0
SHIRPA	hindpaw size	both	0.0 %	1.00
SHIRPA	limb grasp	females	0.0 %	1.00
SHIRPA	limb grasp	males	7.0 %	0.375
SHIRPA	limb grasp	both	3.0 %	0.645
SHIRPA	lower lip morphology	females	0.0 %	1.00
SHIRPA	lower lip morphology	males	0.0 %	1.0
SHIRPA	lower lip morphology	both	0.0 %	1.00
SHIRPA	lower teeth appearance	females	0.0 %	1.0
SHIRPA	lower teeth appearance	males	0.0 %	1.00
SHIRPA	lower teeth appearance	both	0.0 %	1.0
SHIRPA	mouth morphology	females	0.0 %	1.0
SHIRPA	mouth morphology	males	0.0 %	1.00
SHIRPA	mouth morphology	both	0.0 %	1.0
SHIRPA	salivation	females	0.0 %	1.0
SHIRPA	salivation	males	0.0 %	1.0
SHIRPA	salivation	both	0.0 %	1.0
SHIRPA	skin color back paws	females	0.0 %	1.0
SHIRPA	skin color back paws	males	0.0 %	1.0
SHIRPA	skin color back paws	both	0.0 %	1.0
SHIRPA	skin color ear	females	0.0 %	1.0
SHIRPA	skin color ear	males	0.0 %	1.0
SHIRPA	skin color ear	both	0.0 %	1.0
SHIRPA	skin color front paws	females	0.0 %	1.0
SHIRPA	skin color front paws	males	0.0 %	1.0
SHIRPA	skin color front paws	both	0.0 %	1.0
SHIRPA	skin color snout	females	0.0 %	1.0
SHIRPA	skin color snout	males	0.0 %	1.0
SHIRPA	skin color snout	both	0.0 %	1.0
SHIRPA	skin color tail	females	0.0 %	1.0
SHIRPA	skin color tail	males	0.0 %	1.0
SHIRPA	skin color tail	both	0.0 %	1.00
SHIRPA	skin color whole body	females	0.0 %	1.00
SHIRPA	skin color whole body	males	0.0 %	1.0
SHIRPA	skin color whole body	both	0.0 %	1.00
SHIRPA	skin texture back paw	females	0.0 %	1.0
SHIRPA	skin texture back paw	males	0.0 %	1.0
SHIRPA	skin texture back paw	both	0.0 %	1.00
SHIRPA	skin texture ear	females	0.0 %	1.0
SHIRPA	skin texture ear	males	0.0 %	1.0
SHIRPA	skin texture ear	both	0.0 %	1.0
SHIRPA	skin texture front paws	females	0.0 %	1.0
SHIRPA	skin texture front paws	males	0.0 %	1.0
SHIRPA	skin texture front paws	both	0.0 %	1.0
SHIRPA	skin texture snout	females	0.0 %	1.0
SHIRPA	skin texture snout	males	0.0 %	1.0
SHIRPA	skin texture snout	both	0.0 %	1.0
SHIRPA	skin texture tail	females	0.0 %	1.0
SHIRPA	skin texture tail	males	0.0 %	1.0
SHIRPA	skin texture tail	both	0.0 %	1.0
SHIRPA	skin texture whole body	females	0.0 %	1.0
SHIRPA	skin texture whole body	males	0.0 %	1.00
SHIRPA	skin texture whole body	both	0.0 %	1.00
SHIRPA	snout size	females	0.0 %	1.0
SHIRPA	snout size	males	1.0 %	1.0
SHIRPA	snout size	both	0.0 %	1.00
SHIRPA	startle response	females	0.0 %	1.00
SHIRPA	startle response	males	0.0 %	1.00
SHIRPA	startle response	both	0.0 %	1.0
SHIRPA	tail curvature	females	0.0 %	1.0
SHIRPA	tail curvature	males	0.0 %	1.0
SHIRPA	tail curvature	both	0.0 %	1.00
SHIRPA	tail elevation	females	1.0 %	1.00
SHIRPA	tail elevation	males	2.0 %	1.0
SHIRPA	tail elevation	both	1.0 %	1.0
SHIRPA	tail length	females	0.0 %	1.00
SHIRPA	tail length	males	0.0 %	1.0
SHIRPA	tail length	both	0.0 %	1.0
SHIRPA	tail morphology	females	0.0 %	1.00
SHIRPA	tail morphology	males	0.0 %	1.0
SHIRPA	tail morphology	both	0.0 %	1.00
SHIRPA	tail presence	females	0.0 %	1.0
SHIRPA	tail presence	males	0.0 %	1.0
SHIRPA	tail presence	both	0.0 %	1.0
SHIRPA	tail shape	females	0.0 %	1.00
SHIRPA	tail shape	males	0.0 %	1.0
SHIRPA	tail shape	both	0.0 %	1.0
SHIRPA	tail thickness	females	0.0 %	1.0
SHIRPA	tail thickness	males	0.0 %	1.0
SHIRPA	tail thickness	both	0.0 %	1.0
SHIRPA	teeth presence	females	0.0 %	1.0
SHIRPA	teeth presence	males	0.0 %	1.00
SHIRPA	teeth presence	both	0.0 %	1.0
SHIRPA	transfer arousal	females	1.0 %	1.0
SHIRPA	transfer arousal	males	12.0 %	0.0653
SHIRPA	transfer arousal	both	5.0 %	0.129
SHIRPA	tremor	females	0.0 %	1.0
SHIRPA	tremor	males	0.0 %	1.0
SHIRPA	tremor	both	0.0 %	1.0
SHIRPA	trunk curl	females	0.0 %	1.00
SHIRPA	trunk curl	males	0.0 %	1.0
SHIRPA	trunk curl	both	0.0 %	1.0
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	females	0.0 %	1.0
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	males	0.0 %	1.0
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	both	0.0 %	1.0
SHIRPA	upper lip morphology	females	0.0 %	1.0
SHIRPA	upper lip morphology	males	0.0 %	1.0
SHIRPA	upper lip morphology	both	0.0 %	1.0
SHIRPA	upper teeth appearance	females	0.0 %	1.00
SHIRPA	upper teeth appearance	males	0.0 %	1.0
SHIRPA	upper teeth appearance	both	0.0 %	1.0
SHIRPA	vibrissae appearance	females	2.0 %	1.0
SHIRPA	vibrissae appearance	males	1.0 %	1.0
SHIRPA	vibrissae appearance	both	1.0 %	1.0
SHIRPA	vibrissae presence	females	2.0 %	1.0
SHIRPA	vibrissae presence	males	1.0 %	1.0
SHIRPA	vibrissae presence	both	2.0 %	1.0
SHIRPA	vocalization	females	2.0 %	1.0
SHIRPA	vocalization	males	2.0 %	1.0
SHIRPA	vocalization	both	2.0 %	1.0

GENOTYPE CORRELATION PLOT

Correlate Ppip5k2^{tm1b(EUCOMM)Wtsi} -/+ with genotype: