MPD: JaxKOMP-EAP genotype: Itga8<sup>tm1b(KOMP)Wtsi</sup> -/+

MULTIPLE (NUMERIC) TRAIT PROFILE PLOT — Early Adult Phenotyping study (EAP)

Procedure	JaxKOMP-EAP Trait	Trait Effect	Trait Effect SE	Trait Effect RankZ	Adjusted p-value	Unadjusted p-value
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 6 kHz pip	-6.0358	6.7148	-1.6852	0.816	0.464
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 12 kHz pip	-11.181	5.6145	-1.7969	0.676	0.185
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 18 kHz pip	-7.3089	5.6266	-1.5543	0.686	0.324
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 24 kHz pip	2.4772	7.6631	0.27579	0.919	0.777
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 30 kHz pip	-3.5902	2.7623	-0.58224	0.678	0.323
body composition	body length	-0.10765	0.052709	-0.94823	0.237	0.0533
body composition	body weight (at time of DXA)	-0.71950	0.90699	-0.44625	0.648	0.436
body composition	bone area, whole body scan, head excluded	-0.20252	0.13219	-0.65745	0.393	0.140
body composition	bone mineral content of whole body scan, head excluded	-0.014080	0.011067	-0.63224	0.494	0.217
body composition	bone mineral content to body weight ratio	-0.00032426	0.00045548	-0.24968	0.723	0.484
body composition	bone mineral density of whole body scan, head excluded	-0.00049277	0.00069544	-0.50336	0.747	0.486
body composition	fat tissue mass of whole body scan, head excluded	0.63841	0.30798	0.95013	0.208	0.0501
body composition	fat tissue mass to body weight ratio	0.030466	0.010956	1.2650	0.0755	0.0109
body composition	lean tissue mass of whole body scan, head excluded	-0.53171	0.24408	-1.1979	0.225	0.0404
body composition	lean tissue mass to body weight ratio	-0.0028354	0.0097350	-0.20705	0.891	0.774
body composition	percent fat, whole body scan, head excluded	2.5708	1.0190	1.1841	0.112	0.0194
body composition	ratio of soft-tissue attenuation coefficients	-0.0028577	0.0011322	-1.1828	0.110	0.0193
body composition	tissue area	0.37058	0.18206	1.2643	0.253	0.0540
body composition	total tissue mass, whole body scan, head excluded	0.10670	0.24108	0.030040	0.826	0.662
clinical blood chemistry	alanine transaminase (plasma ALT)	-0.93380	7.0713	-0.11146	0.968	0.896
clinical blood chemistry	albumin (plasma Alb)	1.4468	0.50077	2.0106	0.109	0.00852
clinical blood chemistry	alkaline phosphatase (plasma ALP)	9.0000	4.2316	0.98530	0.182	0.0444
clinical blood chemistry	aspartate transaminase (plasma AST)	-30.062	22.940	-1.2972	0.524	0.203
clinical blood chemistry	aspartate transaminase to alanine transaminase ratio (plasma AST:ALT)	-0.56404	0.34316	-1.5788	0.490	0.114
clinical blood chemistry	blood urea nitrogen (BUN)	3.4808	1.1074	1.3422	0.0540	0.00472
clinical blood chemistry	calcium (plasma Ca)	0.37500	0.088496	2.2421	0.00792	0.000312
clinical blood chemistry	carbon dioxide (plasma CO₂)	0.16375	0.99644	-0.14670	0.926	0.871
clinical blood chemistry	chloride (plasma Cl)	0.75759	0.62808	0.58693	0.425	0.241
clinical blood chemistry	glucose (plasma GLU, no fast)	-85.795	21.443	-2.2231	0.00723	0.000602
clinical blood chemistry	HDL cholesterol (plasma HDL)	3.2922	1.7260	0.46625	0.289	0.0696
clinical blood chemistry	HDL cholesterol to total cholesterol ratio	-0.010150	0.0083235	-0.69473	0.572	0.235
clinical blood chemistry	iron (plasma Fe)	0.0057500	0.0062622	0.49863	0.627	0.368
clinical blood chemistry	non-esterified fatty acids (plasma NEFA)	0.1765	0.071744	1.5678	0.150	0.0218
clinical blood chemistry	phosphorus (plasma phosphate)	-0.22500	0.40476	-0.42500	0.800	0.584
clinical blood chemistry	potassium (plasma K)	-0.13062	0.19083	-1.3205	0.648	0.500
clinical blood chemistry	sodium (plasma Na)	2.8950	0.64710	1.8212	0.00128	0.000173
clinical blood chemistry	total bilirubin (plasma TBIL)	-0.0097500	0.011487	-0.73174	0.742	0.405
clinical blood chemistry	total cholesterol (plasma CHOL, no fast)	6.5717	2.4514	0.85507	0.115	0.0137
clinical blood chemistry	total protein (plasma TP)	1.8697	0.56714	1.3100	0.0508	0.00329
clinical blood chemistry	triglyceride (plasma TG, no fast)	20.988	14.867	1.2534	0.449	0.171
ECT	applied stimulus (current), by day, day 2	-0.24476	0.43658	-1.0155	0.786	0.583
ECT	applied stimulus (current), by day, day 3	-0.056194	0.55863	-0.58469	0.965	0.921
ECT	behavior following applied stimulus (current), by day, day 1	-0.050000	0.35798	0.058652	0.977	0.890
ECT	behavior following applied stimulus (current), by day, day 3	0.27373	0.46710	0.51220	0.902	0.564
ECT	stimulus level (current) required for minimal clonic forebrain seizure (score of 3 or higher)	-0.067887	0.44433	-0.57297	0.948	0.880
EKG	duration of PQ interval	-1.3550	1.1072	-1.2048	0.786	0.233
EKG	duration of PR interval	-1.0188	0.95695	-0.90901	0.845	0.298
EKG	duration of QRS interval	0.1525	0.43498	0.28175	0.967	0.729
EKG	duration of QT interval	-1.0113	1.4142	-0.80988	0.891	0.482
EKG	duration of QTC interval, calculated by dividing QT interval by square root of preceding RR interval	-1.3388	1.4582	-1.3657	0.875	0.368
EKG	duration of RR interval	0.66375	1.1984	0.60767	0.843	0.585
EKG	duration of ST interval	-1.1963	1.3634	-0.92435	0.811	0.389
EKG	heart rate coefficient of variation (signal intensity)	-0.11375	0.33404	0.018136	0.960	0.737
EKG	heart rate variability, mean of differences between sequential beats; beats per min	-1.05	2.3278	-0.018136	0.932	0.656
EKG	heart rate, beats per min	-4.7000	10.443	-0.54277	0.870	0.657
EKG	mean R amplitude, mean amplitude of signal measured from isoelectric line to peak of QRS	0.16988	0.14119	1.2043	0.610	0.241
EKG	mean SR amplitude, mean amplitude of signal measured from signal minimum line to peak of QRS	0.36575	0.19081	1.8963	0.349	0.0678
EKG	number of signals	-2.5375	1.5117	-0.55988	0.605	0.107
EKG	QT dispersion, measured as inter-lead variability of QT intervals	3.6627	2.0431	1.0282	0.858	0.0868
EKG	QTc dispersion, calculated as rate-corrected QT dispersion	3.8836	2.2940	1.0180	0.835	0.105
EKG	root mean square of successive differences of neighboring RR intervals	-0.2215	0.22702	-0.0060450	0.860	0.339
electroretinography	a-wave amplitude of rod photoreceptors, left	-14.851	28.552	-1.3092	0.839	0.605
electroretinography	a-wave amplitude of rod photoreceptors, right	13.974	22.037	0.28222	0.828	0.528
electroretinography	b-wave amplitude of cone photoreceptors, left	21.156	13.963	1.5341	0.672	0.135
electroretinography	b-wave amplitude of cone photoreceptors, right	9.7155	11.933	0.93786	0.839	0.419
electroretinography	b-wave amplitude of rod photoreceptors, left	52.568	51.021	1.3275	0.673	0.307
electroretinography	b-wave amplitude of rod photoreceptors, right	2.2618	34.720	0.47208	0.973	0.948
electroretinography	b-wave implicit time of rod photoreceptors (interval from onset of stimulus to peak of the wave), right	0.57830	0.69113	0.45234	0.771	0.406
electroretinography	rod a wave implicit time, left	0.095172	0.60377	-0.27216	0.958	0.875
electroretinography	rod a wave implicit time, right	0.65010	0.55544	0.41940	0.650	0.246
electroretinography	rod b wave implicit time, right	1.7325	1.7679	0.69964	0.809	0.331
glucose tolerance test	amount glucose injected	-8.5708	4.8547	-1.7566	0.416	0.0920
glucose tolerance test	plasma glucose, 0min	6.0883	4.5708	0.39436	0.403	0.197
glucose tolerance test	plasma glucose, 15min	6.5250	19.999	0.30100	0.909	0.747
glucose tolerance test	plasma glucose, 30min	-14.338	19.233	-0.32840	0.745	0.464
glucose tolerance test	plasma glucose, 60min	-31.966	11.863	-1.2261	0.145	0.0136
glucose tolerance test	plasma glucose, 120min	-10.063	11.377	-0.81876	0.670	0.386
grip strength	body weight (at time of grip strength test)	-0.52250	0.70298	-0.27166	0.650	0.466
grip strength	forelimb and hindlimb grip strength (mean of trials), average	4.5051	12.237	0.56449	0.853	0.717
grip strength	forelimb and hindlimb grip strength (mean of trials), average normalized to bw	-0.0077452	0.63226	0.19141	0.994	0.990
grip strength	forelimb and hindlimb grip strength by trial, trial1	9.7109	12.618	0.91687	0.720	0.451
grip strength	forelimb and hindlimb grip strength by trial, trial2	-2.1091	17.226	0.11060	0.956	0.904
grip strength	forelimb and hindlimb grip strength by trial, trial3	10.503	16.929	0.91245	0.765	0.542
grip strength	forelimb grip strength (mean of trials), average	22.203	5.5253	2.6019	0.0147	0.000674
grip strength	forelimb grip strength (mean of trials), average normalized to bw	1.0250	0.30015	2.3547	0.0365	0.00261
grip strength	forelimb grip strength by trial, trial1	32.446	8.4274	3.2488	0.0348	0.000929
grip strength	forelimb grip strength by trial, trial2	9.2727	9.3646	1.2018	0.658	0.333
grip strength	forelimb grip strength by trial, trial3	20.609	8.7385	2.2518	0.196	0.0286
heart weight	heart weight, normalized to body weight	0.62012	0.39727	1.3815	0.313	0.133
heart weight	heart weight, weight	15.286	9.8421	1.4138	0.318	0.134
insulin blood level	insulin (plasma)	-107.43	157.56	0.033550	0.756	0.498
light / dark	fecal boli count, 20 min test	1.1729	0.51895	1.2570	0.361	0.0341
light / dark	latency to enter dark zone, 20 min test	-48.876	41.629	-1.0183	0.670	0.252
light / dark	number of transitions between light and dark zones, 20 min test	-8.1250	8.2538	-0.70971	0.644	0.335
light / dark	percentage of total time in dark zone, 20 min test	12.056	4.6203	2.1674	0.212	0.0157
light / dark	percentage of total time in light zone, 20 min test	-12.056	4.6203	-2.1674	0.209	0.0157
light / dark	time mobile in dark zone, 20 min test	12.808	15.194	0.64841	0.697	0.408
light / dark	time mobile in light zone, 20 min test	-35.276	12.723	-2.3171	0.0864	0.0111
light / dark	time spent in dark zone, 20 min test	174.12	52.778	2.4048	0.100	0.00314
light / dark	time spent in light zone, 20 min test	-174.12	52.778	-2.4048	0.100	0.00314
open field	average speed in center of arena, 20 min test	-0.063750	0.60167	-0.21169	0.973	0.917
open field	average speed in periphery of arena, 20 min test	0.12802	0.12243	0.0046991	0.534	0.307
open field	distance traveled habituation ratio, 20 min test	32.952	15.272	2.2147	0.254	0.0416
open field	distance traveled in center of arena, 20 min test	165.73	66.114	0.68421	0.114	0.0197
open field	distance traveled in periphery of arena, 20 min test	42.208	137.14	-0.26835	0.881	0.761
open field	distance traveled slope, 20 min test	33.184	14.111	2.2819	0.206	0.0276
open field	distance traveled, 20 min test, 1st 5min	-162.46	105.96	-1.5731	0.351	0.139
open field	distance traveled, 20 min test, 2nd 5min	65.100	50.903	0.22819	0.447	0.214
open field	distance traveled, 20 min test, 3rd 5min	170.94	48.165	1.3054	0.0214	0.00171
open field	distance traveled, 20 min test, 4th 5min	134.1	55.736	0.98945	0.130	0.0246
open field	number of clockwise revolution episodes, 20 min test	0.81250	1.0292	0.064524	0.761	0.438
open field	number of counter-clockwise revolution episodes, 20 min test	-0.3625	1.1963	-0.61458	0.891	0.765
open field	number of fecal boli, 20 min test	1.0875	0.92589	1.0753	0.586	0.252
open field	number of rears in 5 min bins, 20 min test, 1st 5min	-5.0375	3.5582	-1.5282	0.422	0.170
open field	number of rears in 5 min bins, 20 min test, 2nd 5min	5.0500	3.0494	0.96137	0.354	0.111
open field	number of rears in 5 min bins, 20 min test, 3rd 5min	9.3375	3.1187	1.6441	0.0679	0.00648
open field	number of rears in 5 min bins, 20 min test, 4th 5min	1.6000	2.8280	0.015440	0.782	0.577
open field	percentage of total time in center of arena, 20 min test	5.8579	2.5919	1.0669	0.234	0.0336
open field	percentage of total time in center of arena, slope, 20 min test	-1.4375	1.7705	-0.68082	0.830	0.425
open field	percentage of total time in center, habituation ratio, 20 min test	-1.6025	1.8986	-0.73077	0.826	0.407
open field	percentage of total time in corners of arena, 20 min test	-6.1386	4.4634	-0.85780	0.489	0.182
open field	percentage of total time in corners, habituation ratio, 20 min test	1.8425	2.3116	0.56820	0.852	0.434
open field	percentage of total time in corners, slope, 20 min test	1.0396	2.2546	0.20209	0.926	0.649
open field	permanence time in center of arena, 20 min test	70.28	31.095	1.0669	0.234	0.0336
open field	permanence time in corners of arena, 20 min test	-73.656	53.562	-0.85780	0.489	0.182
open field	permanence time in periphery of arena, 20 min test	-70.272	31.090	-1.0693	0.234	0.0336
open field	total distance traveled, 20 min test	207.94	162.58	0.12857	0.420	0.214
open field	total number of rears, 20 min test	9.4668	9.5015	0.30894	0.587	0.330
open field	whole arena average speed, 20 min test	0.17262	0.13549	0.12586	0.423	0.215
open field	whole arena resting time, 20 min test	-16.246	16.739	0.078623	0.545	0.342
open field	whole arena time spent mobile, 20 min test	15.903	16.753	0.15434	0.567	0.352
open field	whole arena time spent vertical, 20 min test	9.5213	8.9934	0.62434	0.610	0.301
plasma chemistry analysis	free fatty acids (plasma)	-0.038500	0.10460	0.53839	0.784	0.716
plasma chemistry analysis	plasma cholesterol	9.2778	4.2334	1.7055	0.168	0.0393
plasma chemistry analysis	plasma glucose (4h fast)	20.985	6.5235	2.2198	0.0332	0.00397
plasma chemistry analysis	plasma HDL	7.6401	3.4905	1.5781	0.157	0.0395
plasma chemistry analysis	plasma triglycerides (4h fast)	5.4111	5.9473	1.1531	0.584	0.373
rotarod	learning difference on accelerating rotarod (4-40 rpm/5 min) over 5 trials	0.41884	11.869	0.24964	0.979	0.972
rotarod	learning slope on accelerating rotarod (4-40 rpm/5 min) over 5 trials	-0.66689	3.4263	0.062932	0.956	0.847
rotarod	mean duration on accelerating rotarod (4-40 rpm/5 min) over 5 trials	10.865	13.667	1.2302	0.779	0.435
rotarod	mean latency to fall off accelerating rotarod (4-40 rpm/ 5 min) over 5 trials	0.93750	17.324	0.38194	0.989	0.957
SHIRPA	locomotor activity (number of squares in the arena the mouse moves into with all four paws in first 30 s of test)	0.55266	1.6909	0.41944	0.914	0.747
tail suspension	duration of immobility, 5 min test	14.695	12.279	0.47905	0.495	0.244
tail suspension	latency to immobility, 5 min test	-2.4194	1.6438	-0.60375	0.673	0.155

MULTIPLE (CATEGORICAL) TRAIT PROFILE PLOT — Early Adult Phenotyping study (EAP)

Procedure	JaxKOMP-EAP Trait	Sex	Trait Effect	P-value
electroretinography	blind eyes, left	females	0.0 %	1.0
electroretinography	blind eyes, left	males	0.0 %	1.0
electroretinography	blind eyes, left	both	0.0 %	1.0
electroretinography	blind eyes, right	females	0.0 %	1.0
electroretinography	blind eyes, right	males	0.0 %	1.0
electroretinography	blind eyes, right	both	0.0 %	1.0
eye morphology	anterior chamber depth	females	1.0 %	1.0
eye morphology	anterior chamber depth	males	0.0 %	1.0
eye morphology	anterior chamber depth	both	1.0 %	1.0
eye morphology	bulging eye	females	1.0 %	1.0
eye morphology	bulging eye	males	0.0 %	1.0
eye morphology	bulging eye	both	1.0 %	1.00
eye morphology	cornea	females	4.0 %	1.0
eye morphology	cornea	males	2.0 %	1.0
eye morphology	cornea	both	3.0 %	1.00
eye morphology	cornea opacity	females	5.0 %	1.00
eye morphology	cornea opacity	males	1.0 %	1.0
eye morphology	cornea opacity	both	3.0 %	1.00
eye morphology	cornea vascularization	females	3.0 %	1.0
eye morphology	cornea vascularization	males	1.0 %	1.0
eye morphology	cornea vascularization	both	2.0 %	1.00
eye morphology	corneal deposits	females	2.0 %	1.0
eye morphology	corneal deposits	males	1.0 %	1.0
eye morphology	corneal deposits	both	1.0 %	1.00
eye morphology	corneal mineralization	females	2.0 %	1.0
eye morphology	corneal mineralization	males	1.0 %	1.0
eye morphology	corneal mineralization	both	1.0 %	1.00
eye morphology	corneal scleralization	females	3.0 %	1.00
eye morphology	corneal scleralization	males	1.0 %	1.0
eye morphology	corneal scleralization	both	2.0 %	1.00
eye morphology	corneal ulcer	females	1.0 %	1.0
eye morphology	corneal ulcer	males	1.0 %	1.0
eye morphology	corneal ulcer	both	1.0 %	1.00
eye morphology	eye closure	females	1.0 %	1.00
eye morphology	eye closure	males	0.0 %	1.0
eye morphology	eye closure	both	1.0 %	1.0
eye morphology	eye hemorrhage or blood presence	females	2.0 %	1.00
eye morphology	eye hemorrhage or blood presence	males	1.0 %	1.0
eye morphology	eye hemorrhage or blood presence	both	1.0 %	1.00
eye morphology	eyelid morphology	females	1.0 %	1.0
eye morphology	eyelid morphology	males	0.0 %	1.0
eye morphology	eyelid morphology	both	1.0 %	1.0
eye morphology	eyes (present, absent)	females	1.0 %	1.0
eye morphology	eyes (present, absent)	males	0.0 %	1.0
eye morphology	eyes (present, absent)	both	0.0 %	1.0
eye morphology	fusion between cornea and lens	females	4.0 %	1.00
eye morphology	fusion between cornea and lens	males	2.0 %	1.0
eye morphology	fusion between cornea and lens	both	3.0 %	1.00
eye morphology	iris pigmentation	females	12.0 %	0.0354
eye morphology	iris pigmentation	males	1.0 %	1.0
eye morphology	iris pigmentation	both	6.0 %	0.0759
eye morphology	iris transillumination	females	2.0 %	1.00
eye morphology	iris transillumination	males	1.0 %	1.0
eye morphology	iris transillumination	both	1.0 %	1.00
eye morphology	irispupil	females	4.0 %	1.00
eye morphology	irispupil	males	3.0 %	1.0
eye morphology	irispupil	both	3.0 %	1.00
eye morphology	lacrimation	females	12.0 %	0.0434
eye morphology	lacrimation	males	12.0 %	0.0846
eye morphology	lacrimation	both	10.0 %	0.0141
eye morphology	lens	females	28.0 %	0.0648
eye morphology	lens	males	9.0 %	0.496
eye morphology	lens	both	16.0 %	0.103
eye morphology	lens opacity	females	9.0 %	1.0
eye morphology	lens opacity	males	6.0 %	1.0
eye morphology	lens opacity	both	7.0 %	1.00
eye morphology	narrow eye opening	females	2.0 %	1.0
eye morphology	narrow eye opening	males	1.0 %	1.0
eye morphology	narrow eye opening	both	1.0 %	1.0
eye morphology	optic disc	females	4.0 %	1.00
eye morphology	optic disc	males	2.0 %	1.0
eye morphology	optic disc	both	3.0 %	1.00
eye morphology	persistence of hyaloid vascular system	females	18.0 %	0.373
eye morphology	persistence of hyaloid vascular system	males	5.0 %	1.0
eye morphology	persistence of hyaloid vascular system	both	8.0 %	0.504
eye morphology	pupil dilation	females	2.0 %	1.0
eye morphology	pupil dilation	males	1.0 %	1.0
eye morphology	pupil dilation	both	2.0 %	1.0
eye morphology	pupil light response	females	2.0 %	1.00
eye morphology	pupil light response	males	1.0 %	1.0
eye morphology	pupil light response	both	2.0 %	1.00
eye morphology	pupil position	females	4.0 %	1.00
eye morphology	pupil position	males	3.0 %	1.0
eye morphology	pupil position	both	4.0 %	1.00
eye morphology	pupil shape	females	3.0 %	1.00
eye morphology	pupil shape	males	2.0 %	1.0
eye morphology	pupil shape	both	3.0 %	1.00
eye morphology	retina	females	10.0 %	1.0
eye morphology	retina	males	7.0 %	0.750
eye morphology	retina	both	7.0 %	0.888
eye morphology	retinal blood vessels	females	4.0 %	1.0
eye morphology	retinal blood vessels	males	2.0 %	1.0
eye morphology	retinal blood vessels	both	3.0 %	1.0
eye morphology	retinal blood vessels pattern	females	12.0 %	0.139
eye morphology	retinal blood vessels pattern	males	2.0 %	1.0
eye morphology	retinal blood vessels pattern	both	6.0 %	0.173
eye morphology	retinal blood vessels structure	females	4.0 %	1.00
eye morphology	retinal blood vessels structure	males	2.0 %	1.0
eye morphology	retinal blood vessels structure	both	3.0 %	1.00
eye morphology	retinal pigmentation	females	12.0 %	1.0
eye morphology	retinal pigmentation	males	14.0 %	1.0
eye morphology	retinal pigmentation	both	13.0 %	1.0
eye morphology	retinal structure	females	4.0 %	1.00
eye morphology	retinal structure	males	2.0 %	1.0
eye morphology	retinal structure	both	3.0 %	1.00
eye morphology	synechia	females	4.0 %	1.0
eye morphology	synechia	males	2.0 %	1.0
eye morphology	synechia	both	3.0 %	1.00
eye morphology	vitreous	females	4.0 %	1.00
eye morphology	vitreous	males	2.0 %	1.0
eye morphology	vitreous	both	3.0 %	1.00
rotarod	outcome of accelerating rotarod (4-40 rpm/ 5 min) over 5 trials	females	0.0 %	1.0
rotarod	outcome of accelerating rotarod (4-40 rpm/ 5 min) over 5 trials	males	0.0 %	1.0
rotarod	outcome of accelerating rotarod (4-40 rpm/ 5 min) over 5 trials	both	0.0 %	1.0
rotarod	trial number	females	0.0 %	1.0
rotarod	trial number	males	0.0 %	1.0
rotarod	trial number	both	0.0 %	1.0
SHIRPA	activity body position	females	1.0 %	1.0
SHIRPA	activity body position	males	2.0 %	1.0
SHIRPA	activity body position	both	1.0 %	1.00
SHIRPA	aggression	females	0.0 %	1.00
SHIRPA	aggression	males	1.0 %	1.0
SHIRPA	aggression	both	1.0 %	1.0
SHIRPA	body length	females	0.0 %	1.0
SHIRPA	body length	males	0.0 %	1.00
SHIRPA	body length	both	0.0 %	1.00
SHIRPA	body position	females	0.0 %	1.0
SHIRPA	body position	males	1.0 %	1.0
SHIRPA	body position	both	0.0 %	1.0
SHIRPA	body thickness	females	1.0 %	1.0
SHIRPA	body thickness	males	0.0 %	1.0
SHIRPA	body thickness	both	0.0 %	1.0
SHIRPA	coat color abdomen	females	9.0 %	0.250
SHIRPA	coat color abdomen	males	4.0 %	1.0
SHIRPA	coat color abdomen	both	3.0 %	0.440
SHIRPA	coat color back	females	0.0 %	1.0
SHIRPA	coat color back	males	0.0 %	1.00
SHIRPA	coat color back	both	0.0 %	1.00
SHIRPA	coat color head	females	0.0 %	1.0
SHIRPA	coat color head	males	0.0 %	1.00
SHIRPA	coat color head	both	0.0 %	1.0
SHIRPA	coat color pattern abdomen	females	12.0 %	0.0461
SHIRPA	coat color pattern abdomen	males	1.0 %	1.0
SHIRPA	coat color pattern abdomen	both	6.0 %	0.0959
SHIRPA	coat color pattern back	females	0.0 %	1.0
SHIRPA	coat color pattern back	males	0.0 %	1.00
SHIRPA	coat color pattern back	both	0.0 %	1.0
SHIRPA	coat color pattern head	females	0.0 %	1.0
SHIRPA	coat color pattern head	males	0.0 %	1.0
SHIRPA	coat color pattern head	both	0.0 %	1.00
SHIRPA	coat hair abdomen texture appearance	females	2.0 %	1.0
SHIRPA	coat hair abdomen texture appearance	males	2.0 %	1.0
SHIRPA	coat hair abdomen texture appearance	both	2.0 %	1.0
SHIRPA	coat hair back texture appearance	females	0.0 %	1.0
SHIRPA	coat hair back texture appearance	males	0.0 %	1.0
SHIRPA	coat hair back texture appearance	both	0.0 %	1.0
SHIRPA	coat hair distribution abdomen	females	0.0 %	1.0
SHIRPA	coat hair distribution abdomen	males	1.0 %	1.00
SHIRPA	coat hair distribution abdomen	both	1.0 %	1.00
SHIRPA	coat hair distribution back	females	0.0 %	1.0
SHIRPA	coat hair distribution back	males	0.0 %	1.0
SHIRPA	coat hair distribution back	both	0.0 %	1.0
SHIRPA	coat hair distribution head	females	1.0 %	1.00
SHIRPA	coat hair distribution head	males	1.0 %	1.0
SHIRPA	coat hair distribution head	both	1.0 %	1.0
SHIRPA	coat hair head texture appearance	females	0.0 %	1.00
SHIRPA	coat hair head texture appearance	males	0.0 %	1.0
SHIRPA	coat hair head texture appearance	both	0.0 %	1.0
SHIRPA	contact righting	females	5.0 %	1.0
SHIRPA	contact righting	males	5.0 %	1.00
SHIRPA	contact righting	both	5.0 %	1.00
SHIRPA	ear morphology	females	0.0 %	1.0
SHIRPA	ear morphology	males	0.0 %	1.0
SHIRPA	ear morphology	both	0.0 %	1.0
SHIRPA	fat distribution	females	0.0 %	1.0
SHIRPA	fat distribution	males	0.0 %	1.0
SHIRPA	fat distribution	both	0.0 %	1.00
SHIRPA	forelimb digit number	females	0.0 %	1.00
SHIRPA	forelimb digit number	males	0.0 %	1.0
SHIRPA	forelimb digit number	both	0.0 %	1.00
SHIRPA	forelimb digit position	females	0.0 %	1.0
SHIRPA	forelimb digit position	males	0.0 %	1.0
SHIRPA	forelimb digit position	both	0.0 %	1.0
SHIRPA	forelimb digit shape	females	0.0 %	1.0
SHIRPA	forelimb digit shape	males	0.0 %	1.0
SHIRPA	forelimb digit shape	both	0.0 %	1.0
SHIRPA	forelimb digit size	females	0.0 %	1.0
SHIRPA	forelimb digit size	males	0.0 %	1.0
SHIRPA	forelimb digit size	both	0.0 %	1.0
SHIRPA	forelimb footpads	females	0.0 %	1.0
SHIRPA	forelimb footpads	males	0.0 %	1.0
SHIRPA	forelimb footpads	both	0.0 %	1.0
SHIRPA	forelimb nail length	females	0.0 %	1.0
SHIRPA	forelimb nail length	males	0.0 %	1.0
SHIRPA	forelimb nail length	both	0.0 %	1.0
SHIRPA	forelimb nail number	females	0.0 %	1.0
SHIRPA	forelimb nail number	males	0.0 %	1.0
SHIRPA	forelimb nail number	both	0.0 %	1.0
SHIRPA	forelimb nail position	females	0.0 %	1.0
SHIRPA	forelimb nail position	males	0.0 %	1.0
SHIRPA	forelimb nail position	both	0.0 %	1.0
SHIRPA	forelimb nail shape	females	0.0 %	1.0
SHIRPA	forelimb nail shape	males	0.0 %	1.0
SHIRPA	forelimb nail shape	both	0.0 %	1.0
SHIRPA	forelimbs position	females	0.0 %	1.0
SHIRPA	forelimbs position	males	0.0 %	1.0
SHIRPA	forelimbs position	both	0.0 %	1.0
SHIRPA	forelimbs shape	females	0.0 %	1.0
SHIRPA	forelimbs shape	males	0.0 %	1.0
SHIRPA	forelimbs shape	both	0.0 %	1.0
SHIRPA	forelimbs size	females	0.0 %	1.0
SHIRPA	forelimbs size	males	0.0 %	1.0
SHIRPA	forelimbs size	both	0.0 %	1.0
SHIRPA	forepaw position	females	0.0 %	1.0
SHIRPA	forepaw position	males	0.0 %	1.0
SHIRPA	forepaw position	both	0.0 %	1.0
SHIRPA	forepaw shape	females	0.0 %	1.0
SHIRPA	forepaw shape	males	0.0 %	1.0
SHIRPA	forepaw shape	both	0.0 %	1.0
SHIRPA	forepaw size	females	0.0 %	1.0
SHIRPA	forepaw size	males	0.0 %	1.0
SHIRPA	forepaw size	both	0.0 %	1.0
SHIRPA	gait (fluidity)	females	0.0 %	1.0
SHIRPA	gait (fluidity)	males	0.0 %	1.00
SHIRPA	gait (fluidity)	both	0.0 %	1.00
SHIRPA	genitalia morphology	females	0.0 %	1.00
SHIRPA	genitalia morphology	males	0.0 %	1.0
SHIRPA	genitalia morphology	both	0.0 %	1.00
SHIRPA	genitalia presence	females	0.0 %	1.0
SHIRPA	genitalia presence	males	0.0 %	1.0
SHIRPA	genitalia presence	both	0.0 %	1.0
SHIRPA	genitalia size	females	0.0 %	1.0
SHIRPA	genitalia size	males	0.0 %	1.0
SHIRPA	genitalia size	both	0.0 %	1.0
SHIRPA	head bobbing	females	0.0 %	1.0
SHIRPA	head bobbing	males	0.0 %	1.0
SHIRPA	head bobbing	both	0.0 %	1.0
SHIRPA	head morphology	females	0.0 %	1.0
SHIRPA	head morphology	males	0.0 %	1.00
SHIRPA	head morphology	both	0.0 %	1.0
SHIRPA	head size	females	0.0 %	1.0
SHIRPA	head size	males	0.0 %	1.0
SHIRPA	head size	both	0.0 %	1.00
SHIRPA	hindlimb digit number	females	1.0 %	1.00
SHIRPA	hindlimb digit number	males	0.0 %	1.0
SHIRPA	hindlimb digit number	both	0.0 %	1.00
SHIRPA	hindlimb digit position	females	0.0 %	1.0
SHIRPA	hindlimb digit position	males	0.0 %	1.0
SHIRPA	hindlimb digit position	both	0.0 %	1.0
SHIRPA	hindlimb digit shape	females	0.0 %	1.0
SHIRPA	hindlimb digit shape	males	0.0 %	1.0
SHIRPA	hindlimb digit shape	both	0.0 %	1.0
SHIRPA	hindlimb digit size	females	0.0 %	1.00
SHIRPA	hindlimb digit size	males	0.0 %	1.0
SHIRPA	hindlimb digit size	both	0.0 %	1.00
SHIRPA	hindlimb nail length	females	0.0 %	1.0
SHIRPA	hindlimb nail length	males	0.0 %	1.0
SHIRPA	hindlimb nail length	both	0.0 %	1.00
SHIRPA	hindlimb nail number	females	0.0 %	1.0
SHIRPA	hindlimb nail number	males	1.0 %	1.0
SHIRPA	hindlimb nail number	both	0.0 %	1.00
SHIRPA	hindlimb nail position	females	0.0 %	1.0
SHIRPA	hindlimb nail position	males	0.0 %	1.0
SHIRPA	hindlimb nail position	both	0.0 %	1.0
SHIRPA	hindlimb nail shape	females	0.0 %	1.0
SHIRPA	hindlimb nail shape	males	0.0 %	1.0
SHIRPA	hindlimb nail shape	both	0.0 %	1.0
SHIRPA	hindlimbs footpads	females	0.0 %	1.0
SHIRPA	hindlimbs footpads	males	0.0 %	1.0
SHIRPA	hindlimbs footpads	both	0.0 %	1.0
SHIRPA	hindlimbs position	females	0.0 %	1.0
SHIRPA	hindlimbs position	males	0.0 %	1.0
SHIRPA	hindlimbs position	both	0.0 %	1.0
SHIRPA	hindlimbs shape	females	0.0 %	1.0
SHIRPA	hindlimbs shape	males	0.0 %	1.0
SHIRPA	hindlimbs shape	both	0.0 %	1.0
SHIRPA	hindlimbs size	females	0.0 %	1.0
SHIRPA	hindlimbs size	males	0.0 %	1.0
SHIRPA	hindlimbs size	both	0.0 %	1.0
SHIRPA	hindpaw position	females	0.0 %	1.0
SHIRPA	hindpaw position	males	0.0 %	1.0
SHIRPA	hindpaw position	both	0.0 %	1.0
SHIRPA	hindpaw shape	females	0.0 %	1.0
SHIRPA	hindpaw shape	males	0.0 %	1.0
SHIRPA	hindpaw shape	both	0.0 %	1.0
SHIRPA	hindpaw size	females	0.0 %	1.0
SHIRPA	hindpaw size	males	0.0 %	1.0
SHIRPA	hindpaw size	both	0.0 %	1.0
SHIRPA	limb grasp	females	9.0 %	1.00
SHIRPA	limb grasp	males	6.0 %	1.0
SHIRPA	limb grasp	both	7.0 %	0.624
SHIRPA	lower lip morphology	females	0.0 %	1.0
SHIRPA	lower lip morphology	males	0.0 %	1.0
SHIRPA	lower lip morphology	both	0.0 %	1.0
SHIRPA	lower teeth appearance	females	0.0 %	1.0
SHIRPA	lower teeth appearance	males	0.0 %	1.00
SHIRPA	lower teeth appearance	both	0.0 %	1.00
SHIRPA	mouth morphology	females	0.0 %	1.0
SHIRPA	mouth morphology	males	0.0 %	1.00
SHIRPA	mouth morphology	both	0.0 %	1.00
SHIRPA	salivation	females	0.0 %	1.0
SHIRPA	salivation	males	0.0 %	1.0
SHIRPA	salivation	both	0.0 %	1.0
SHIRPA	skin color back paws	females	0.0 %	1.0
SHIRPA	skin color back paws	males	0.0 %	1.0
SHIRPA	skin color back paws	both	0.0 %	1.0
SHIRPA	skin color ear	females	0.0 %	1.0
SHIRPA	skin color ear	males	0.0 %	1.0
SHIRPA	skin color ear	both	0.0 %	1.0
SHIRPA	skin color front paws	females	0.0 %	1.0
SHIRPA	skin color front paws	males	0.0 %	1.0
SHIRPA	skin color front paws	both	0.0 %	1.0
SHIRPA	skin color snout	females	0.0 %	1.0
SHIRPA	skin color snout	males	0.0 %	1.0
SHIRPA	skin color snout	both	0.0 %	1.0
SHIRPA	skin color tail	females	0.0 %	1.0
SHIRPA	skin color tail	males	0.0 %	1.0
SHIRPA	skin color tail	both	0.0 %	1.0
SHIRPA	skin color whole body	females	0.0 %	1.0
SHIRPA	skin color whole body	males	0.0 %	1.0
SHIRPA	skin color whole body	both	0.0 %	1.0
SHIRPA	skin texture back paw	females	0.0 %	1.0
SHIRPA	skin texture back paw	males	0.0 %	1.0
SHIRPA	skin texture back paw	both	0.0 %	1.0
SHIRPA	skin texture ear	females	0.0 %	1.0
SHIRPA	skin texture ear	males	0.0 %	1.0
SHIRPA	skin texture ear	both	0.0 %	1.0
SHIRPA	skin texture front paws	females	0.0 %	1.0
SHIRPA	skin texture front paws	males	0.0 %	1.0
SHIRPA	skin texture front paws	both	0.0 %	1.0
SHIRPA	skin texture snout	females	0.0 %	1.0
SHIRPA	skin texture snout	males	0.0 %	1.0
SHIRPA	skin texture snout	both	0.0 %	1.0
SHIRPA	skin texture tail	females	0.0 %	1.0
SHIRPA	skin texture tail	males	0.0 %	1.0
SHIRPA	skin texture tail	both	0.0 %	1.0
SHIRPA	skin texture whole body	females	0.0 %	1.0
SHIRPA	skin texture whole body	males	0.0 %	1.00
SHIRPA	skin texture whole body	both	0.0 %	1.00
SHIRPA	snout size	females	0.0 %	1.0
SHIRPA	snout size	males	1.0 %	1.0
SHIRPA	snout size	both	0.0 %	1.0
SHIRPA	startle response	females	0.0 %	1.00
SHIRPA	startle response	males	0.0 %	1.00
SHIRPA	startle response	both	0.0 %	1.00
SHIRPA	tail curvature	females	0.0 %	1.00
SHIRPA	tail curvature	males	0.0 %	1.0
SHIRPA	tail curvature	both	0.0 %	1.0
SHIRPA	tail elevation	females	1.0 %	1.00
SHIRPA	tail elevation	males	2.0 %	1.0
SHIRPA	tail elevation	both	1.0 %	1.0
SHIRPA	tail length	females	0.0 %	1.0
SHIRPA	tail length	males	0.0 %	1.0
SHIRPA	tail length	both	0.0 %	1.00
SHIRPA	tail morphology	females	0.0 %	1.00
SHIRPA	tail morphology	males	0.0 %	1.0
SHIRPA	tail morphology	both	0.0 %	1.00
SHIRPA	tail presence	females	0.0 %	1.0
SHIRPA	tail presence	males	0.0 %	1.0
SHIRPA	tail presence	both	0.0 %	1.0
SHIRPA	tail shape	females	0.0 %	1.0
SHIRPA	tail shape	males	0.0 %	1.0
SHIRPA	tail shape	both	0.0 %	1.00
SHIRPA	tail thickness	females	0.0 %	1.0
SHIRPA	tail thickness	males	0.0 %	1.0
SHIRPA	tail thickness	both	0.0 %	1.0
SHIRPA	teeth presence	females	0.0 %	1.0
SHIRPA	teeth presence	males	0.0 %	1.00
SHIRPA	teeth presence	both	0.0 %	1.00
SHIRPA	touch escape	females	14.0 %	0.606
SHIRPA	touch escape	males	14.0 %	0.611
SHIRPA	touch escape	both	14.0 %	0.161
SHIRPA	transfer arousal	females	1.0 %	1.0
SHIRPA	transfer arousal	males	2.0 %	1.00
SHIRPA	transfer arousal	both	1.0 %	1.0
SHIRPA	tremor	females	0.0 %	1.0
SHIRPA	tremor	males	0.0 %	1.0
SHIRPA	tremor	both	0.0 %	1.00
SHIRPA	trunk curl	females	0.0 %	1.00
SHIRPA	trunk curl	males	0.0 %	1.0
SHIRPA	trunk curl	both	0.0 %	1.0
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	females	0.0 %	1.0
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	males	0.0 %	1.0
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	both	0.0 %	1.00
SHIRPA	upper lip morphology	females	0.0 %	1.0
SHIRPA	upper lip morphology	males	0.0 %	1.0
SHIRPA	upper lip morphology	both	0.0 %	1.0
SHIRPA	upper teeth appearance	females	0.0 %	1.0
SHIRPA	upper teeth appearance	males	0.0 %	1.0
SHIRPA	upper teeth appearance	both	0.0 %	1.00
SHIRPA	vibrissae appearance	females	2.0 %	1.0
SHIRPA	vibrissae appearance	males	1.0 %	1.0
SHIRPA	vibrissae appearance	both	1.0 %	1.0
SHIRPA	vibrissae presence	females	2.0 %	1.00
SHIRPA	vibrissae presence	males	1.0 %	1.0
SHIRPA	vibrissae presence	both	2.0 %	1.0
SHIRPA	vocalization	females	2.0 %	1.00
SHIRPA	vocalization	males	2.0 %	1.0
SHIRPA	vocalization	both	2.0 %	1.00
tail suspension	climbing, 5 min test (yes, no)	females	22.0 %	0.213
tail suspension	climbing, 5 min test (yes, no)	males	22.0 %	0.212
tail suspension	climbing, 5 min test (yes, no)	both	22.0 %	0.0307

GENOTYPE CORRELATION PLOT

Correlate Itga8^{tm1b(KOMP)Wtsi} -/+ with genotype: