MPD: JaxKOMP-EAP genotype: Hsf4<sup>tm1b(KOMP)Wtsi</sup> -/-

JaxKOMP-EAP effect sizes: Hsf4^{tm1b(KOMP)Wtsi} -/- Gene Hsf4

MULTIPLE (NUMERIC) TRAIT PROFILE PLOT — Early Adult Phenotyping study (EAP)

Procedure	JaxKOMP-EAP Trait	Trait Effect	Trait Effect SE	Trait Effect RankZ	Adjusted p-value	Unadjusted p-value
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 6 kHz pip	3.9835	1.5746	0.89841	0.269	0.0216
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 12 kHz pip	2.0876	2.9554	0.49808	0.835	0.489
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 18 kHz pip	0.54124	2.1012	-0.056127	0.937	0.800
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 24 kHz pip	2.5387	3.1693	0.29485	0.754	0.434
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 30 kHz pip	4.0077	3.2661	0.62088	0.631	0.236
body composition	body length	-0.095017	0.045462	-0.85738	0.204	0.0411
body composition	body weight (at time of DXA)	0.34375	0.53000	0.38084	0.724	0.519
body composition	bone area, whole body scan, head excluded	-0.38435	0.14242	-1.2121	0.0739	0.00914
body composition	bone mineral content of whole body scan, head excluded	-0.022677	0.010275	-1.0444	0.166	0.0314
body composition	bone mineral content to body weight ratio	-0.00086798	0.00038343	-0.89987	0.141	0.0273
body composition	bone mineral density of whole body scan, head excluded	-0.00039817	0.00044443	-0.41529	0.668	0.374
body composition	fat tissue mass of whole body scan, head excluded	0.30064	0.21464	0.49610	0.400	0.167
body composition	fat tissue mass to body weight ratio	0.011380	0.0083591	0.58297	0.406	0.179
body composition	lean tissue mass of whole body scan, head excluded	-0.24851	0.24527	-0.67449	0.614	0.315
body composition	lean tissue mass to body weight ratio	-0.011718	0.0082713	-0.70001	0.410	0.162
body composition	percent fat, whole body scan, head excluded	1.1369	0.79629	0.59760	0.380	0.159
body composition	ratio of soft-tissue attenuation coefficients	-0.0012612	0.00088483	-0.60728	0.382	0.160
body composition	tissue area	-0.026600	0.16632	0.097192	0.961	0.874
body composition	total tissue mass, whole body scan, head excluded	-0.063932	0.22649	-0.37007	0.888	0.779
clinical blood chemistry	alanine transaminase (plasma ALT)	42.185	21.674	1.7557	0.370	0.0565
clinical blood chemistry	albumin (plasma Alb)	1.2313	0.33951	1.6842	0.0263	0.000614
clinical blood chemistry	alkaline phosphatase (plasma ALP)	3.6779	2.9494	0.12573	0.474	0.217
clinical blood chemistry	aspartate transaminase (plasma AST)	39.785	20.209	1.3205	0.304	0.0538
clinical blood chemistry	aspartate transaminase to alanine transaminase ratio (plasma AST:ALT)	-0.14240	0.22156	-0.44740	0.830	0.523
clinical blood chemistry	blood urea nitrogen (BUN)	0.47184	1.2917	0.16484	0.861	0.716
clinical blood chemistry	calcium (plasma Ca)	0.059099	0.066503	0.75859	0.618	0.378
clinical blood chemistry	carbon dioxide (plasma CO₂)	-0.42763	0.53660	-0.71568	0.684	0.429
clinical blood chemistry	chloride (plasma Cl)	-0.0010496	0.47522	-0.076613	0.998	0.998
clinical blood chemistry	glucose (plasma GLU, no fast)	0.21198	13.401	0.30384	0.991	0.987
clinical blood chemistry	HDL cholesterol (plasma HDL)	0.97928	2.0719	-0.092945	0.858	0.638
clinical blood chemistry	HDL cholesterol to total cholesterol ratio	-0.0082392	0.011793	-0.60847	0.772	0.488
clinical blood chemistry	iron (plasma Fe)	-0.00080414	0.0056367	-0.036092	0.946	0.887
clinical blood chemistry	non-esterified fatty acids (plasma NEFA)	0.054055	0.065251	0.47176	0.650	0.411
clinical blood chemistry	phosphorus (plasma phosphate)	0.062040	0.22724	0.056318	0.903	0.786
clinical blood chemistry	potassium (plasma K)	0.28861	0.17016	0.13168	0.218	0.0952
clinical blood chemistry	sodium (plasma Na)	0.56583	0.54793	-0.33311	0.437	0.306
clinical blood chemistry	total bilirubin (plasma TBIL)	0.020715	0.010674	1.2334	0.285	0.0572
clinical blood chemistry	total cholesterol (plasma CHOL, no fast)	1.7445	2.4170	0.077566	0.762	0.473
clinical blood chemistry	total protein (plasma TP)	1.1254	0.49946	0.83392	0.185	0.0281
clinical blood chemistry	triglyceride (plasma TG, no fast)	1.1704	9.3810	0.27825	0.957	0.901
ECT	applied stimulus (current), by day, day 2	0.32596	0.31822	0.57089	0.610	0.313
ECT	applied stimulus (current), by day, day 3	0.62762	0.32257	1.3217	0.264	0.0595
ECT	behavior following applied stimulus (current), by day, day 1	-0.50591	0.37459	-0.88870	0.487	0.185
ECT	behavior following applied stimulus (current), by day, day 3	0.32011	0.34608	0.65124	0.826	0.361
ECT	stimulus level (current) required for minimal clonic forebrain seizure (score of 3 or higher)	0.48028	0.22944	1.1708	0.206	0.0434
EKG	duration of PQ interval	-1.1729	0.89859	-1.0282	0.778	0.206
EKG	duration of PR interval	-1.0996	0.86999	-0.96207	0.771	0.219
EKG	duration of QRS interval	-0.34422	0.35806	-1.0454	0.885	0.347
EKG	duration of QT interval	-3.3647	0.88005	-2.6504	0.135	0.000990
EKG	duration of QTC interval, calculated by dividing QT interval by square root of preceding RR interval	-2.0937	0.75078	-1.9216	0.475	0.0107
EKG	duration of RR interval	-4.9301	2.1358	-1.9477	0.350	0.0308
EKG	duration of ST interval	-3.0107	0.79452	-2.5883	0.0894	0.00101
EKG	heart rate coefficient of variation (signal intensity)	-4.3162	2.0372	-3.1545	0.694	0.0456
EKG	heart rate variability, mean of differences between sequential beats; beats per min	-29.974	15.485	-2.9464	0.761	0.0659
EKG	heart rate, beats per min	36.008	17.206	1.8068	0.360	0.0481
EKG	mean R amplitude, mean amplitude of signal measured from isoelectric line to peak of QRS	0.038250	0.067739	0.21851	0.845	0.578
EKG	mean SR amplitude, mean amplitude of signal measured from signal minimum line to peak of QRS	0.090090	0.10694	0.42263	0.723	0.409
EKG	number of signals	5.8268	3.3025	1.0701	0.605	0.0915
EKG	QT dispersion, measured as inter-lead variability of QT intervals	-0.55433	3.0784	-0.13135	0.987	0.859
EKG	QTc dispersion, calculated as rate-corrected QT dispersion	0.47054	3.2226	0.13338	0.986	0.885
EKG	root mean square of successive differences of neighboring RR intervals	-3.2197	2.0059	-1.5523	0.843	0.123
glucose tolerance test	amount glucose injected	-1.9139	1.3614	-0.20844	0.531	0.166
glucose tolerance test	plasma glucose, 0min	-5.2265	3.6143	-0.73701	0.344	0.155
glucose tolerance test	plasma glucose, 15min	31.074	20.982	0.99257	0.447	0.145
glucose tolerance test	plasma glucose, 30min	11.700	18.761	0.45902	0.790	0.536
glucose tolerance test	plasma glucose, 60min	22.121	15.422	0.96596	0.463	0.158
glucose tolerance test	plasma glucose, 120min	2.9973	6.0944	0.076949	0.843	0.625
grip strength	body weight (at time of grip strength test)	1.1215	0.49255	1.1966	0.102	0.0294
grip strength	forelimb and hindlimb grip strength (mean of trials), average	-12.106	10.018	-0.61460	0.443	0.236
grip strength	forelimb and hindlimb grip strength (mean of trials), average normalized to bw	-0.61086	0.47849	-0.70862	0.410	0.211
grip strength	forelimb and hindlimb grip strength by trial, trial1	-8.3917	12.073	-0.33280	0.751	0.492
grip strength	forelimb and hindlimb grip strength by trial, trial2	-37.502	13.708	-2.0978	0.0808	0.0101
grip strength	forelimb and hindlimb grip strength by trial, trial3	3.4323	11.679	0.43764	0.902	0.771
grip strength	forelimb grip strength (mean of trials), average	-1.8110	4.9014	0.023239	0.877	0.714
grip strength	forelimb grip strength (mean of trials), average normalized to bw	-0.27504	0.22797	-0.45690	0.511	0.236
grip strength	forelimb grip strength by trial, trial1	3.8977	5.9256	0.71798	0.801	0.515
grip strength	forelimb grip strength by trial, trial2	2.1136	6.9838	0.46175	0.917	0.764
grip strength	forelimb grip strength by trial, trial3	-5.6845	6.9731	-0.38079	0.727	0.421
heart weight	heart weight, normalized to body weight	0.63413	0.27110	1.4212	0.107	0.0228
heart weight	heart weight, weight	15.580	6.7665	1.4400	0.119	0.0250
hematology	basophil differential (percent of total WBC)	0.040027	0.039995	0.64125	0.735	0.328
hematology	calculated hemoglobin (cHGB)	-0.049126	0.18035	-0.42819	0.898	0.788
hematology	eosinophil differential (percent of total WBC)	-0.12757	0.25671	-0.27629	0.881	0.624
hematology	hematocrit (HCT)	0.53533	0.65802	0.22886	0.682	0.425
hematology	hemoglobin concentration distribution width (HDW)	-0.053756	0.032741	-1.3398	0.387	0.115
hematology	large unstained cells (percent of total WBC)	0.12867	0.12073	0.83570	0.641	0.299
hematology	lymphocyte differential (percent of total WBC)	-2.3187	2.6719	-0.99769	0.628	0.395
hematology	mean corpuscular hemoglobin (CHr)	-0.067770	0.067228	-0.54979	0.567	0.325
hematology	mean platelet volume (MPV)	-0.21622	0.15996	-1.2963	0.398	0.190
hematology	mean RBC corpuscular hemoglobin (MCH)	-0.14602	0.096464	-0.56420	0.480	0.144
hematology	mean RBC corpuscular hemoglobin concentration (MCHC)	-0.52391	0.28283	-0.89965	0.374	0.0774
hematology	mean RBC corpuscular volume (MCV)	0.39149	0.27401	0.70658	0.363	0.167
hematology	measured hemoglobin (mHGB)	-0.093189	0.20890	-0.47926	0.832	0.660
hematology	monocyte differential (percent of total WBC)	0.12886	0.19349	0.63972	0.790	0.512
hematology	neutrophil differential (percent of total WBC)	2.1085	2.5893	1.0437	0.638	0.424
hematology	platelet count (PLT; units per volume x 10³)	-103.69	102.01	-1.2229	0.672	0.320
hematology	RBC corpuscular distribution width (RDW)	-0.21316	0.11557	-0.80280	0.286	0.0786
hematology	RBC corpuscular hemoglobin concentration mean (CHCM)	-0.37600	0.27839	-1.0394	0.437	0.191
hematology	red blood cell count (RBC; per volume x 10⁶)	0.038077	0.13721	-0.18717	0.898	0.784
hematology	reticulocyte count (Retic; units per volume x 10⁹)	-8.7207	13.385	-0.30189	0.820	0.521
hematology	reticulocyte differential (percent of total RBC)	0.00033333	0.18851	0.21489	0.999	0.999
hematology	white blood cell count (WBC; units per volume x 10³)	0.60973	0.55819	0.59181	0.491	0.286
insulin blood level	insulin (plasma)	-543.87	318.35	-2.0160	0.524	0.0912
light / dark	fecal boli count, 20 min test	0.062534	0.70798	0.073074	0.969	0.930
light / dark	latency to enter dark zone, 20 min test	-27.442	31.224	-0.60887	0.763	0.383
light / dark	number of transitions between light and dark zones, 20 min test	3.5109	5.1693	0.41741	0.759	0.500
light / dark	percentage of total time in dark zone, 20 min test	0.73470	2.4197	0.27519	0.921	0.762
light / dark	percentage of total time in light zone, 20 min test	-0.73470	2.4197	-0.28081	0.922	0.762
light / dark	time mobile in dark zone, 20 min test	3.7387	11.962	0.14654	0.897	0.756
light / dark	time mobile in light zone, 20 min test	-3.7749	8.3032	-0.51851	0.824	0.651
light / dark	time spent in dark zone, 20 min test	32.037	33.281	0.70277	0.722	0.339
light / dark	time spent in light zone, 20 min test	-32.037	33.281	-0.70277	0.722	0.339
open field	average speed in center of arena, 20 min test	0.42618	0.35235	0.67070	0.582	0.231
open field	average speed in periphery of arena, 20 min test	0.25398	0.14375	0.46088	0.227	0.0819
open field	distance traveled habituation ratio, 20 min test	-3.8880	8.1706	-0.28649	0.844	0.636
open field	distance traveled in center of arena, 20 min test	214.21	70.072	0.94866	0.0350	0.00323
open field	distance traveled in periphery of arena, 20 min test	186.74	146.97	0.29629	0.441	0.208
open field	distance traveled slope, 20 min test	-5.7188	7.8592	-0.47586	0.744	0.469
open field	distance traveled, 20 min test, 1st 5min	116.26	74.814	0.57136	0.332	0.125
open field	distance traveled, 20 min test, 2nd 5min	144.02	56.115	1.0716	0.0778	0.0125
open field	distance traveled, 20 min test, 3rd 5min	70.719	53.925	0.33866	0.423	0.194
open field	distance traveled, 20 min test, 4th 5min	87.239	46.409	0.49550	0.230	0.0646
open field	number of clockwise revolution episodes, 20 min test	3.1177	1.0245	1.2359	0.0570	0.00336
open field	number of counter-clockwise revolution episodes, 20 min test	1.3874	0.92348	0.31035	0.401	0.138
open field	number of fecal boli, 20 min test	-0.17932	0.71108	0.13948	0.919	0.802
open field	number of rears in 5 min bins, 20 min test, 1st 5min	2.3068	2.0347	0.42337	0.529	0.261
open field	number of rears in 5 min bins, 20 min test, 2nd 5min	2.8494	2.1262	0.38887	0.469	0.185
open field	number of rears in 5 min bins, 20 min test, 3rd 5min	6.8052	2.0935	1.2191	0.0317	0.00181
open field	number of rears in 5 min bins, 20 min test, 4th 5min	5.1404	2.1118	0.78444	0.141	0.0176
open field	percentage of total time in center of arena, 20 min test	3.0649	2.0162	0.46986	0.437	0.133
open field	percentage of total time in center of arena, slope, 20 min test	0.82642	1.1242	0.57928	0.840	0.465
open field	percentage of total time in center, habituation ratio, 20 min test	0.94884	1.2261	0.63416	0.841	0.442
open field	percentage of total time in corners of arena, 20 min test	-8.1950	2.8043	-1.1913	0.0758	0.00475
open field	percentage of total time in corners, habituation ratio, 20 min test	-0.65364	1.9080	-0.60005	0.947	0.733
open field	percentage of total time in corners, slope, 20 min test	0.061722	1.8229	-0.23647	0.995	0.973
open field	permanence time in center of arena, 20 min test	36.776	24.195	0.46986	0.437	0.133
open field	permanence time in corners of arena, 20 min test	-98.348	33.652	-1.1913	0.0758	0.00475
open field	permanence time in periphery of arena, 20 min test	-36.772	24.198	-0.46986	0.436	0.133
open field	total distance traveled, 20 min test	400.95	185.11	0.63909	0.130	0.0339
open field	total number of rears, 20 min test	17.323	6.8159	0.84814	0.0895	0.0134
open field	whole arena average speed, 20 min test	0.33306	0.15432	0.62924	0.131	0.0346
open field	whole arena resting time, 20 min test	-35.838	18.254	-0.43712	0.173	0.0538
open field	whole arena time spent mobile, 20 min test	35.921	18.252	0.68761	0.171	0.0533
open field	whole arena time spent vertical, 20 min test	19.314	8.0886	1.3508	0.162	0.0198
plasma chemistry analysis	free fatty acids (plasma)	0.10555	0.090335	1.2496	0.384	0.247
plasma chemistry analysis	plasma cholesterol	1.2146	2.5993	0.43882	0.761	0.642
plasma chemistry analysis	plasma glucose (4h fast)	2.2020	6.8457	0.89639	0.886	0.749
plasma chemistry analysis	plasma HDL	3.3874	2.3782	0.67103	0.370	0.159
plasma chemistry analysis	plasma triglycerides (4h fast)	-0.94739	5.4374	0.62293	0.902	0.862
rotarod	learning difference on accelerating rotarod (4-40 rpm/5 min) over 5 trials	-24.264	12.019	-1.6975	0.583	0.0481
rotarod	learning slope on accelerating rotarod (4-40 rpm/5 min) over 5 trials	-6.3930	3.9093	-1.4251	0.712	0.107
rotarod	mean duration on accelerating rotarod (4-40 rpm/5 min) over 5 trials	-8.4514	9.3467	-0.47553	0.749	0.370
rotarod	mean latency to fall off accelerating rotarod (4-40 rpm/ 5 min) over 5 trials	-16.525	14.239	-0.72324	0.788	0.250
SHIRPA	locomotor activity (number of squares in the arena the mouse moves into with all four paws in first 30 s of test)	0.090909	1.5857	0.24180	0.990	0.955
startle / PPI	average baseline movement during background noise	0.79565	0.36769	0.60107	0.516	0.0442
startle / PPI	average of each corrected maximum percent pre-pulse inhibition value	-0.096409	0.063877	-0.96556	0.487	0.149
startle / PPI	average of each corrected percent pre-pulse inhibition value	-0.10737	0.066972	-1.1325	0.456	0.127
startle / PPI	average of maximum percent pre-pulse inhibition for each pre-pulse tested	-7.6813	5.6761	-0.65404	0.516	0.193
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-17.279	5.4573	-1.7351	0.498	0.00564
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-6.8347	6.6155	-0.70515	0.671	0.315
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	1.8741	5.8109	0.090496	0.905	0.751
startle / PPI	average startle response to full pulse (120 dB)	37.874	12.463	0.94128	0.0505	0.00706
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	33.817	10.071	0.84722	0.0297	0.00350
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	11.075	8.2167	0.43278	0.407	0.194
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	6.7746	8.4707	0.37350	0.638	0.434
startle / PPI	average startle response to pre-pulse, 74dB sound pressure level	-0.23898	0.49095	-0.11726	0.928	0.633
startle / PPI	average startle response to pre-pulse, 78dB sound pressure level	-1.6440	0.70228	-1.1279	0.444	0.0317
startle / PPI	average startle response to pre-pulse, 82dB sound pressure level	0.80944	1.0226	0.22394	0.798	0.440
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-0.19256	0.073439	-1.6155	0.663	0.0178
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-0.14643	0.076037	-1.2934	0.355	0.0701
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	0.0097092	0.067096	-0.098292	0.949	0.887
startle / PPI	corrected average startle response to full pulse (120 dB) minus average baseline movement during background noise	37.058	12.370	0.93042	0.0536	0.00775
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 74dB sound pressure level	33.123	10.271	0.82931	0.0362	0.00470
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 78dB sound pressure level	12.680	8.4368	0.47471	0.353	0.150
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 82dB sound pressure level	3.5315	7.7905	0.28765	0.793	0.656
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-0.25777	0.070713	-1.8947	0.256	0.00200
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-0.14045	0.076771	-1.1682	0.379	0.0840
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-0.021489	0.077210	-0.35948	0.913	0.784
startle / PPI	corrected maximum startle response to full pulse (120 dB) minus maximum baseline movement during background noise	147.93	51.948	0.98358	0.0668	0.0107
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 74dB sound pressure level	140.99	45.103	0.89431	0.0411	0.00584
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 78dB sound pressure level	50.729	41.312	0.47628	0.451	0.235
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 82dB sound pressure level	10.455	37.623	0.26436	0.878	0.784
startle / PPI	maximum baseline movement during background noise	-3.1708	1.0468	-0.86950	0.309	0.00757
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-22.323	5.3576	-1.9867	0.165	0.000647
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-8.5525	7.2363	-0.83326	0.618	0.253
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	0.39706	6.8843	-0.12856	0.981	0.955
startle / PPI	maximum startle response to full pulse (120 dB)	146.86	52.386	0.98358	0.0701	0.0118
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	141.32	44.485	0.89850	0.0392	0.00522
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	46.013	40.754	0.44203	0.490	0.274
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	18.588	39.366	0.31109	0.784	0.642
startle / PPI	maximum startle response to pre-pulse, 74dB sound pressure level	-1.0931	1.4552	-0.24843	0.839	0.463
startle / PPI	maximum startle response to pre-pulse, 78dB sound pressure level	-2.6549	1.9654	-0.73787	0.699	0.193
startle / PPI	maximum startle response to pre-pulse, 82dB sound pressure level	0.26827	2.7408	-0.10598	0.984	0.923
tail suspension	duration of immobility, 5 min test	13.182	10.671	0.38615	0.471	0.221
tail suspension	latency to immobility, 5 min test	-0.48612	0.97668	0.015379	0.895	0.620

MULTIPLE (CATEGORICAL) TRAIT PROFILE PLOT — Early Adult Phenotyping study (EAP)

In this plot, data points are the computed genotype effect % vs. C57BL/6NJ controls, for all measured categorical phenotypes in JaxKOMP-EAP

Dimensions Width: × Height: px

Plot Options Group by Procedure

Include Sexes Data Both Females Males

Significance Threshold p-Value Threshold

Download Plot

Procedure	JaxKOMP-EAP Trait	Sex	Trait Effect	P-value

eye morphology	anterior chamber depth	females	59.0 %	6.09e-8
eye morphology	anterior chamber depth	males	100.0 %	8.89e-15
eye morphology	anterior chamber depth	both	79.0 %	5.16e-21
eye morphology	bulging eye	females	14.0 %	0.00710
eye morphology	bulging eye	males	0.0 %	1.0
eye morphology	bulging eye	both	7.0 %	0.0106
eye morphology	cornea	females	28.0 %	0.0120
eye morphology	cornea	males	25.0 %	0.000277
eye morphology	cornea	both	24.0 %	0.0000561
eye morphology	cornea opacity	females	13.0 %	0.171
eye morphology	cornea opacity	males	1.0 %	1.0
eye morphology	cornea opacity	both	6.0 %	0.234
eye morphology	cornea vascularization	females	3.0 %	1.0
eye morphology	cornea vascularization	males	1.0 %	1.0
eye morphology	cornea vascularization	both	2.0 %	1.0
eye morphology	corneal deposits	females	2.0 %	1.0
eye morphology	corneal deposits	males	1.0 %	1.0
eye morphology	corneal deposits	both	1.0 %	1.00
eye morphology	corneal mineralization	females	2.0 %	1.0
eye morphology	corneal mineralization	males	1.0 %	1.0
eye morphology	corneal mineralization	both	1.0 %	1.0
eye morphology	corneal scleralization	females	14.0 %	0.129
eye morphology	corneal scleralization	males	1.0 %	1.0
eye morphology	corneal scleralization	both	6.0 %	0.132
eye morphology	corneal ulcer	females	1.0 %	1.0
eye morphology	corneal ulcer	males	1.0 %	1.0
eye morphology	corneal ulcer	both	1.0 %	1.0
eye morphology	eye closure	females	1.0 %	1.0
eye morphology	eye closure	males	0.0 %	1.0
eye morphology	eye closure	both	1.0 %	1.0
eye morphology	eye hemorrhage or blood presence	females	2.0 %	1.0
eye morphology	eye hemorrhage or blood presence	males	1.0 %	1.0
eye morphology	eye hemorrhage or blood presence	both	1.0 %	1.0
eye morphology	eyelid morphology	females	1.0 %	1.0
eye morphology	eyelid morphology	males	0.0 %	1.0
eye morphology	eyelid morphology	both	1.0 %	1.0
eye morphology	eyes (present, absent)	females	1.0 %	1.0
eye morphology	eyes (present, absent)	males	0.0 %	1.0
eye morphology	eyes (present, absent)	both	0.0 %	1.0
eye morphology	fusion between cornea and lens	females	39.0 %	0.000615
eye morphology	fusion between cornea and lens	males	61.0 %	3.41e-7
eye morphology	fusion between cornea and lens	both	51.0 %	2.12e-9
eye morphology	iris pigmentation	females	69.0 %	1.60e-11
eye morphology	iris pigmentation	males	99.0 %	6.84e-21
eye morphology	iris pigmentation	both	85.0 %	4.18e-31
eye morphology	iris transillumination	females	2.0 %	1.0
eye morphology	iris transillumination	males	1.0 %	1.0
eye morphology	iris transillumination	both	1.0 %	1.00
eye morphology	irispupil	females	14.0 %	0.0486
eye morphology	irispupil	males	3.0 %	1.0
eye morphology	irispupil	both	7.0 %	0.114
eye morphology	lacrimation	females	28.0 %	0.0178
eye morphology	lacrimation	males	37.0 %	0.000370
eye morphology	lacrimation	both	32.0 %	0.0000124
eye morphology	narrow eye opening	females	2.0 %	1.00
eye morphology	narrow eye opening	males	1.0 %	1.0
eye morphology	narrow eye opening	both	1.0 %	1.00
eye morphology	optic disc	females	69.0 %	0.00000197
eye morphology	optic disc	males	98.0 %	8.75e-13
eye morphology	optic disc	both	85.0 %	3.32e-18
eye morphology	pupil dilation	females	14.0 %	0.0484
eye morphology	pupil dilation	males	1.0 %	1.0
eye morphology	pupil dilation	both	6.0 %	0.0890
eye morphology	pupil light response	females	14.0 %	0.0514
eye morphology	pupil light response	males	1.0 %	1.0
eye morphology	pupil light response	both	6.0 %	0.0846
eye morphology	pupil position	females	14.0 %	0.0563
eye morphology	pupil position	males	12.0 %	0.128
eye morphology	pupil position	both	10.0 %	0.0311
eye morphology	pupil shape	females	40.0 %	0.00000419
eye morphology	pupil shape	males	36.0 %	0.0000515
eye morphology	pupil shape	both	37.0 %	6.38e-10
eye morphology	retinal blood vessels	females	69.0 %	5.64e-7
eye morphology	retinal blood vessels	males	98.0 %	8.77e-14
eye morphology	retinal blood vessels	both	85.0 %	4.22e-19
eye morphology	retinal blood vessels pattern	females	69.0 %	0.00000294
eye morphology	retinal blood vessels pattern	males	98.0 %	6.32e-13
eye morphology	retinal blood vessels pattern	both	85.0 %	4.12e-18
eye morphology	retinal blood vessels structure	females	69.0 %	0.00000189
eye morphology	retinal blood vessels structure	males	98.0 %	3.53e-13
eye morphology	retinal blood vessels structure	both	85.0 %	1.93e-18
eye morphology	retinal structure	females	69.0 %	0.00000192
eye morphology	retinal structure	males	98.0 %	5.35e-13
eye morphology	retinal structure	both	85.0 %	2.84e-18
eye morphology	synechia	females	70.0 %	4.29e-7
eye morphology	synechia	males	98.0 %	6.64e-14
eye morphology	synechia	both	85.0 %	1.28e-19
eye morphology	vitreous	females	69.0 %	7.65e-7
eye morphology	vitreous	males	98.0 %	4.38e-14
eye morphology	vitreous	both	85.0 %	2.65e-19
rotarod	outcome of accelerating rotarod (4-40 rpm/ 5 min) over 5 trials	females	0.0 %	1.0
rotarod	outcome of accelerating rotarod (4-40 rpm/ 5 min) over 5 trials	males	0.0 %	1.0
rotarod	outcome of accelerating rotarod (4-40 rpm/ 5 min) over 5 trials	both	0.0 %	1.0
rotarod	trial number	females	0.0 %	1.0
rotarod	trial number	males	0.0 %	1.0
rotarod	trial number	both	0.0 %	1.0
SHIRPA	activity body position	females	1.0 %	1.0
SHIRPA	activity body position	males	2.0 %	1.0
SHIRPA	activity body position	both	1.0 %	1.00
SHIRPA	aggression	females	0.0 %	1.00
SHIRPA	aggression	males	1.0 %	1.0
SHIRPA	aggression	both	1.0 %	1.0
SHIRPA	body length	females	0.0 %	1.0
SHIRPA	body length	males	0.0 %	1.00
SHIRPA	body length	both	0.0 %	1.00
SHIRPA	body position	females	0.0 %	1.0
SHIRPA	body position	males	1.0 %	1.0
SHIRPA	body position	both	0.0 %	1.0
SHIRPA	body thickness	females	1.0 %	1.0
SHIRPA	body thickness	males	0.0 %	1.0
SHIRPA	body thickness	both	0.0 %	1.0
SHIRPA	coat color abdomen	females	3.0 %	1.00
SHIRPA	coat color abdomen	males	4.0 %	1.0
SHIRPA	coat color abdomen	both	4.0 %	1.0
SHIRPA	coat color back	females	0.0 %	1.0
SHIRPA	coat color back	males	0.0 %	1.00
SHIRPA	coat color back	both	0.0 %	1.00
SHIRPA	coat color head	females	0.0 %	1.0
SHIRPA	coat color head	males	0.0 %	1.00
SHIRPA	coat color head	both	0.0 %	1.0
SHIRPA	coat color pattern abdomen	females	1.0 %	1.0
SHIRPA	coat color pattern abdomen	males	1.0 %	1.0
SHIRPA	coat color pattern abdomen	both	1.0 %	1.0
SHIRPA	coat color pattern back	females	0.0 %	1.0
SHIRPA	coat color pattern back	males	0.0 %	1.00
SHIRPA	coat color pattern back	both	0.0 %	1.0
SHIRPA	coat color pattern head	females	0.0 %	1.0
SHIRPA	coat color pattern head	males	0.0 %	1.0
SHIRPA	coat color pattern head	both	0.0 %	1.00
SHIRPA	coat hair abdomen texture appearance	females	2.0 %	1.0
SHIRPA	coat hair abdomen texture appearance	males	2.0 %	1.0
SHIRPA	coat hair abdomen texture appearance	both	2.0 %	1.0
SHIRPA	coat hair back texture appearance	females	0.0 %	1.0
SHIRPA	coat hair back texture appearance	males	0.0 %	1.0
SHIRPA	coat hair back texture appearance	both	0.0 %	1.0
SHIRPA	coat hair distribution abdomen	females	0.0 %	1.0
SHIRPA	coat hair distribution abdomen	males	1.0 %	1.00
SHIRPA	coat hair distribution abdomen	both	1.0 %	1.00
SHIRPA	coat hair distribution back	females	0.0 %	1.0
SHIRPA	coat hair distribution back	males	0.0 %	1.0
SHIRPA	coat hair distribution back	both	0.0 %	1.0
SHIRPA	coat hair distribution head	females	1.0 %	1.00
SHIRPA	coat hair distribution head	males	1.0 %	1.0
SHIRPA	coat hair distribution head	both	1.0 %	1.0
SHIRPA	coat hair head texture appearance	females	0.0 %	1.00
SHIRPA	coat hair head texture appearance	males	0.0 %	1.0
SHIRPA	coat hair head texture appearance	both	0.0 %	1.0
SHIRPA	contact righting	females	5.0 %	1.0
SHIRPA	contact righting	males	5.0 %	1.00
SHIRPA	contact righting	both	5.0 %	1.00
SHIRPA	ear morphology	females	0.0 %	1.0
SHIRPA	ear morphology	males	0.0 %	1.0
SHIRPA	ear morphology	both	0.0 %	1.0
SHIRPA	fat distribution	females	0.0 %	1.0
SHIRPA	fat distribution	males	0.0 %	1.0
SHIRPA	fat distribution	both	0.0 %	1.00
SHIRPA	forelimb digit number	females	0.0 %	1.00
SHIRPA	forelimb digit number	males	0.0 %	1.0
SHIRPA	forelimb digit number	both	0.0 %	1.00
SHIRPA	forelimb digit position	females	0.0 %	1.0
SHIRPA	forelimb digit position	males	0.0 %	1.0
SHIRPA	forelimb digit position	both	0.0 %	1.0
SHIRPA	forelimb digit shape	females	0.0 %	1.0
SHIRPA	forelimb digit shape	males	0.0 %	1.0
SHIRPA	forelimb digit shape	both	0.0 %	1.0
SHIRPA	forelimb digit size	females	0.0 %	1.0
SHIRPA	forelimb digit size	males	0.0 %	1.0
SHIRPA	forelimb digit size	both	0.0 %	1.0
SHIRPA	forelimb footpads	females	0.0 %	1.0
SHIRPA	forelimb footpads	males	0.0 %	1.0
SHIRPA	forelimb footpads	both	0.0 %	1.0
SHIRPA	forelimb nail length	females	0.0 %	1.0
SHIRPA	forelimb nail length	males	0.0 %	1.0
SHIRPA	forelimb nail length	both	0.0 %	1.0
SHIRPA	forelimb nail number	females	0.0 %	1.0
SHIRPA	forelimb nail number	males	0.0 %	1.0
SHIRPA	forelimb nail number	both	0.0 %	1.0
SHIRPA	forelimb nail position	females	0.0 %	1.0
SHIRPA	forelimb nail position	males	0.0 %	1.0
SHIRPA	forelimb nail position	both	0.0 %	1.0
SHIRPA	forelimb nail shape	females	0.0 %	1.0
SHIRPA	forelimb nail shape	males	0.0 %	1.0
SHIRPA	forelimb nail shape	both	0.0 %	1.0
SHIRPA	forelimbs position	females	0.0 %	1.0
SHIRPA	forelimbs position	males	0.0 %	1.0
SHIRPA	forelimbs position	both	0.0 %	1.0
SHIRPA	forelimbs shape	females	0.0 %	1.0
SHIRPA	forelimbs shape	males	0.0 %	1.0
SHIRPA	forelimbs shape	both	0.0 %	1.0
SHIRPA	forelimbs size	females	0.0 %	1.0
SHIRPA	forelimbs size	males	0.0 %	1.0
SHIRPA	forelimbs size	both	0.0 %	1.0
SHIRPA	forepaw position	females	0.0 %	1.0
SHIRPA	forepaw position	males	0.0 %	1.0
SHIRPA	forepaw position	both	0.0 %	1.0
SHIRPA	forepaw shape	females	0.0 %	1.0
SHIRPA	forepaw shape	males	0.0 %	1.0
SHIRPA	forepaw shape	both	0.0 %	1.0
SHIRPA	forepaw size	females	0.0 %	1.0
SHIRPA	forepaw size	males	0.0 %	1.0
SHIRPA	forepaw size	both	0.0 %	1.0
SHIRPA	gait (fluidity)	females	0.0 %	1.0
SHIRPA	gait (fluidity)	males	0.0 %	1.00
SHIRPA	gait (fluidity)	both	0.0 %	1.00
SHIRPA	genitalia morphology	females	0.0 %	1.00
SHIRPA	genitalia morphology	males	0.0 %	1.0
SHIRPA	genitalia morphology	both	0.0 %	1.00
SHIRPA	genitalia presence	females	0.0 %	1.0
SHIRPA	genitalia presence	males	0.0 %	1.0
SHIRPA	genitalia presence	both	0.0 %	1.0
SHIRPA	genitalia size	females	0.0 %	1.0
SHIRPA	genitalia size	males	0.0 %	1.0
SHIRPA	genitalia size	both	0.0 %	1.0
SHIRPA	head bobbing	females	0.0 %	1.0
SHIRPA	head bobbing	males	0.0 %	1.0
SHIRPA	head bobbing	both	0.0 %	1.0
SHIRPA	head morphology	females	0.0 %	1.0
SHIRPA	head morphology	males	0.0 %	1.00
SHIRPA	head morphology	both	0.0 %	1.0
SHIRPA	head size	females	0.0 %	1.0
SHIRPA	head size	males	0.0 %	1.0
SHIRPA	head size	both	0.0 %	1.00
SHIRPA	hindlimb digit number	females	1.0 %	1.00
SHIRPA	hindlimb digit number	males	0.0 %	1.0
SHIRPA	hindlimb digit number	both	0.0 %	1.00
SHIRPA	hindlimb digit position	females	0.0 %	1.0
SHIRPA	hindlimb digit position	males	0.0 %	1.0
SHIRPA	hindlimb digit position	both	0.0 %	1.0
SHIRPA	hindlimb digit shape	females	0.0 %	1.0
SHIRPA	hindlimb digit shape	males	0.0 %	1.0
SHIRPA	hindlimb digit shape	both	0.0 %	1.0
SHIRPA	hindlimb digit size	females	0.0 %	1.00
SHIRPA	hindlimb digit size	males	0.0 %	1.0
SHIRPA	hindlimb digit size	both	0.0 %	1.00
SHIRPA	hindlimb nail length	females	0.0 %	1.0
SHIRPA	hindlimb nail length	males	0.0 %	1.0
SHIRPA	hindlimb nail length	both	0.0 %	1.00
SHIRPA	hindlimb nail number	females	0.0 %	1.0
SHIRPA	hindlimb nail number	males	1.0 %	1.0
SHIRPA	hindlimb nail number	both	0.0 %	1.00
SHIRPA	hindlimb nail position	females	0.0 %	1.0
SHIRPA	hindlimb nail position	males	0.0 %	1.0
SHIRPA	hindlimb nail position	both	0.0 %	1.0
SHIRPA	hindlimb nail shape	females	0.0 %	1.0
SHIRPA	hindlimb nail shape	males	0.0 %	1.0
SHIRPA	hindlimb nail shape	both	0.0 %	1.0
SHIRPA	hindlimbs footpads	females	0.0 %	1.0
SHIRPA	hindlimbs footpads	males	0.0 %	1.0
SHIRPA	hindlimbs footpads	both	0.0 %	1.0
SHIRPA	hindlimbs position	females	0.0 %	1.0
SHIRPA	hindlimbs position	males	0.0 %	1.0
SHIRPA	hindlimbs position	both	0.0 %	1.0
SHIRPA	hindlimbs shape	females	0.0 %	1.0
SHIRPA	hindlimbs shape	males	0.0 %	1.0
SHIRPA	hindlimbs shape	both	0.0 %	1.0
SHIRPA	hindlimbs size	females	0.0 %	1.0
SHIRPA	hindlimbs size	males	0.0 %	1.0
SHIRPA	hindlimbs size	both	0.0 %	1.0
SHIRPA	hindpaw position	females	0.0 %	1.0
SHIRPA	hindpaw position	males	0.0 %	1.0
SHIRPA	hindpaw position	both	0.0 %	1.0
SHIRPA	hindpaw shape	females	0.0 %	1.0
SHIRPA	hindpaw shape	males	0.0 %	1.0
SHIRPA	hindpaw shape	both	0.0 %	1.0
SHIRPA	hindpaw size	females	0.0 %	1.0
SHIRPA	hindpaw size	males	0.0 %	1.0
SHIRPA	hindpaw size	both	0.0 %	1.0
SHIRPA	limb grasp	females	4.0 %	0.524
SHIRPA	limb grasp	males	6.0 %	1.0
SHIRPA	limb grasp	both	1.0 %	1.0
SHIRPA	lower lip morphology	females	0.0 %	1.0
SHIRPA	lower lip morphology	males	0.0 %	1.0
SHIRPA	lower lip morphology	both	0.0 %	1.0
SHIRPA	lower teeth appearance	females	0.0 %	1.0
SHIRPA	lower teeth appearance	males	0.0 %	1.00
SHIRPA	lower teeth appearance	both	0.0 %	1.00
SHIRPA	mouth morphology	females	0.0 %	1.0
SHIRPA	mouth morphology	males	0.0 %	1.00
SHIRPA	mouth morphology	both	0.0 %	1.00
SHIRPA	salivation	females	0.0 %	1.0
SHIRPA	salivation	males	0.0 %	1.0
SHIRPA	salivation	both	0.0 %	1.0
SHIRPA	skin color back paws	females	0.0 %	1.0
SHIRPA	skin color back paws	males	0.0 %	1.0
SHIRPA	skin color back paws	both	0.0 %	1.0
SHIRPA	skin color ear	females	0.0 %	1.0
SHIRPA	skin color ear	males	0.0 %	1.0
SHIRPA	skin color ear	both	0.0 %	1.0
SHIRPA	skin color front paws	females	0.0 %	1.0
SHIRPA	skin color front paws	males	0.0 %	1.0
SHIRPA	skin color front paws	both	0.0 %	1.0
SHIRPA	skin color snout	females	0.0 %	1.0
SHIRPA	skin color snout	males	0.0 %	1.0
SHIRPA	skin color snout	both	0.0 %	1.0
SHIRPA	skin color tail	females	0.0 %	1.0
SHIRPA	skin color tail	males	0.0 %	1.0
SHIRPA	skin color tail	both	0.0 %	1.0
SHIRPA	skin color whole body	females	0.0 %	1.0
SHIRPA	skin color whole body	males	0.0 %	1.0
SHIRPA	skin color whole body	both	0.0 %	1.0
SHIRPA	skin texture back paw	females	0.0 %	1.0
SHIRPA	skin texture back paw	males	0.0 %	1.0
SHIRPA	skin texture back paw	both	0.0 %	1.0
SHIRPA	skin texture ear	females	0.0 %	1.0
SHIRPA	skin texture ear	males	0.0 %	1.0
SHIRPA	skin texture ear	both	0.0 %	1.0
SHIRPA	skin texture front paws	females	0.0 %	1.0
SHIRPA	skin texture front paws	males	0.0 %	1.0
SHIRPA	skin texture front paws	both	0.0 %	1.0
SHIRPA	skin texture snout	females	0.0 %	1.0
SHIRPA	skin texture snout	males	0.0 %	1.0
SHIRPA	skin texture snout	both	0.0 %	1.0
SHIRPA	skin texture tail	females	0.0 %	1.0
SHIRPA	skin texture tail	males	0.0 %	1.0
SHIRPA	skin texture tail	both	0.0 %	1.0
SHIRPA	skin texture whole body	females	0.0 %	1.0
SHIRPA	skin texture whole body	males	0.0 %	1.00
SHIRPA	skin texture whole body	both	0.0 %	1.00
SHIRPA	snout size	females	0.0 %	1.0
SHIRPA	snout size	males	1.0 %	1.0
SHIRPA	snout size	both	0.0 %	1.0
SHIRPA	startle response	females	0.0 %	1.00
SHIRPA	startle response	males	0.0 %	1.00
SHIRPA	startle response	both	0.0 %	1.00
SHIRPA	tail curvature	females	0.0 %	1.00
SHIRPA	tail curvature	males	0.0 %	1.0
SHIRPA	tail curvature	both	0.0 %	1.0
SHIRPA	tail elevation	females	1.0 %	1.00
SHIRPA	tail elevation	males	2.0 %	1.0
SHIRPA	tail elevation	both	1.0 %	1.0
SHIRPA	tail length	females	0.0 %	1.0
SHIRPA	tail length	males	0.0 %	1.0
SHIRPA	tail length	both	0.0 %	1.00
SHIRPA	tail morphology	females	0.0 %	1.00
SHIRPA	tail morphology	males	0.0 %	1.0
SHIRPA	tail morphology	both	0.0 %	1.00
SHIRPA	tail presence	females	0.0 %	1.0
SHIRPA	tail presence	males	0.0 %	1.0
SHIRPA	tail presence	both	0.0 %	1.0
SHIRPA	tail shape	females	0.0 %	1.0
SHIRPA	tail shape	males	0.0 %	1.0
SHIRPA	tail shape	both	0.0 %	1.00
SHIRPA	tail thickness	females	0.0 %	1.0
SHIRPA	tail thickness	males	0.0 %	1.0
SHIRPA	tail thickness	both	0.0 %	1.0
SHIRPA	teeth presence	females	0.0 %	1.0
SHIRPA	teeth presence	males	0.0 %	1.00
SHIRPA	teeth presence	both	0.0 %	1.00
SHIRPA	touch escape	females	14.0 %	0.606
SHIRPA	touch escape	males	14.0 %	0.611
SHIRPA	touch escape	both	14.0 %	0.161
SHIRPA	transfer arousal	females	1.0 %	1.0
SHIRPA	transfer arousal	males	2.0 %	1.00
SHIRPA	transfer arousal	both	1.0 %	1.0
SHIRPA	tremor	females	0.0 %	1.0
SHIRPA	tremor	males	0.0 %	1.0
SHIRPA	tremor	both	0.0 %	1.00
SHIRPA	trunk curl	females	0.0 %	1.00
SHIRPA	trunk curl	males	0.0 %	1.0
SHIRPA	trunk curl	both	0.0 %	1.0
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	females	0.0 %	1.0
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	males	0.0 %	1.0
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	both	0.0 %	1.00
SHIRPA	upper lip morphology	females	0.0 %	1.0
SHIRPA	upper lip morphology	males	0.0 %	1.0
SHIRPA	upper lip morphology	both	0.0 %	1.0
SHIRPA	upper teeth appearance	females	0.0 %	1.0
SHIRPA	upper teeth appearance	males	0.0 %	1.0
SHIRPA	upper teeth appearance	both	0.0 %	1.00
SHIRPA	vibrissae appearance	females	2.0 %	1.0
SHIRPA	vibrissae appearance	males	1.0 %	1.0
SHIRPA	vibrissae appearance	both	1.0 %	1.0
SHIRPA	vibrissae presence	females	2.0 %	1.00
SHIRPA	vibrissae presence	males	1.0 %	1.0
SHIRPA	vibrissae presence	both	2.0 %	1.0
SHIRPA	vocalization	females	2.0 %	1.00
SHIRPA	vocalization	males	2.0 %	1.0
SHIRPA	vocalization	both	2.0 %	1.00
tail suspension	climbing, 5 min test (yes, no)	females	22.0 %	0.350
tail suspension	climbing, 5 min test (yes, no)	males	22.0 %	0.212
tail suspension	climbing, 5 min test (yes, no)	both	22.0 %	0.0497

GENOTYPE CORRELATION PLOT

Correlate Hsf4^{tm1b(KOMP)Wtsi} -/- with genotype: