MPD: JaxKOMP-EAP genotype: Dixdc1<sup>tm1.1(KOMP)Vlcg</sup> -/+

JaxKOMP-EAP effect sizes: Dixdc1^{tm1.1(KOMP)Vlcg} -/+ Gene Dixdc1

MULTIPLE (NUMERIC) TRAIT PROFILE PLOT — Early Adult Phenotyping study (EAP)

In this plot, data points are the computed genotype effect size vs. C57BL/6NJ controls, for all measured numeric phenotypes in JaxKOMP-EAP

Dimensions Width: × Height: px

Plot Options Group by Procedure Standard Error Show Effect Sizes RankZ

Significance Threshold p-Value Threshold Adjusted Unadjusted

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Procedure	JaxKOMP-EAP Trait	Trait Effect	Trait Effect SE	Trait Effect RankZ	Adjusted p-value	Unadjusted p-value

ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 6 kHz pip	9.8086	4.9806	1.8038	0.425	0.0706
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 12 kHz pip	3.4091	5.7060	0.74233	0.867	0.560
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 18 kHz pip	0.79545	5.5515	-0.0021303	0.964	0.888
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 24 kHz pip	-1.4204	7.2133	-0.33627	0.943	0.847
ABR test	auditory brainstem response (ABR) threshold, sound pressure level, 30 kHz pip	8.6364	6.1322	1.3168	0.570	0.182
body composition	body length	-0.056001	0.041505	-0.46005	0.471	0.183
body composition	body weight (at time of DXA)	-1.5840	0.46851	-1.0055	0.0134	0.00139
body composition	bone area, whole body scan, head excluded	-0.18323	0.13294	-0.56686	0.436	0.174
body composition	bone mineral content of whole body scan, head excluded	-0.0047519	0.010104	-0.14523	0.834	0.640
body composition	bone mineral content to body weight ratio	0.000043589	0.00039000	0.21043	0.965	0.911
body composition	bone mineral density of whole body scan, head excluded	0.00049651	0.00046102	0.58414	0.585	0.287
body composition	fat tissue mass of whole body scan, head excluded	-0.090225	0.34484	-0.16042	0.900	0.795
body composition	fat tissue mass to body weight ratio	-0.0058256	0.011069	-0.21741	0.785	0.601
body composition	lean tissue mass of whole body scan, head excluded	0.11155	0.32693	0.080638	0.895	0.734
body composition	lean tissue mass to body weight ratio	-0.00026609	0.010142	-0.060825	0.993	0.979
body composition	percent fat, whole body scan, head excluded	-0.47957	1.0593	-0.16872	0.822	0.653
body composition	ratio of soft-tissue attenuation coefficients	0.00055171	0.0011793	0.18995	0.815	0.642
body composition	tissue area	-0.24577	0.16930	-0.63637	0.426	0.153
body composition	total tissue mass, whole body scan, head excluded	-0.027343	0.22690	-0.28080	0.958	0.905
ECT	applied stimulus (current), by day, day 2	-0.12077	0.23188	-0.67080	0.787	0.605
ECT	applied stimulus (current), by day, day 3	-0.070972	0.29881	-0.61798	0.954	0.814
ECT	applied stimulus (current), by day, day 4	-0.093750	0.80237	-0.22442	0.989	0.909
ECT	behavior following applied stimulus (current), by day, day 1	0.045477	0.31884	0.35632	0.977	0.887
ECT	behavior following applied stimulus (current), by day, day 3	-0.56992	0.30938	-1.5584	0.654	0.0754
ECT	stimulus level (current) required for minimal clonic forebrain seizure (score of 3 or higher)	0.36269	0.35488	0.80498	0.611	0.313
EKG	duration of PQ interval	-1.4768	0.89361	-1.3020	0.675	0.105
EKG	duration of PR interval	-2.0349	0.97452	-1.7124	0.516	0.0419
EKG	duration of QRS interval	0.091905	0.32128	0.11511	0.976	0.776
EKG	duration of QT interval	-2.5593	1.3068	-2.0860	0.537	0.0558
EKG	duration of QTC interval, calculated by dividing QT interval by square root of preceding RR interval	-0.45164	0.87456	-0.43441	0.935	0.608
EKG	duration of RR interval	-5.0125	2.5951	-1.9613	0.408	0.0591
EKG	duration of ST interval	-2.3542	1.1493	-1.9216	0.482	0.0458
EKG	heart rate coefficient of variation (signal intensity)	-1.7026	0.92338	-1.3760	0.785	0.0711
EKG	heart rate variability, mean of differences between sequential beats; beats per min	-2.6799	5.6206	-0.21318	0.931	0.636
EKG	heart rate, beats per min	32.788	17.268	1.6619	0.384	0.0634
EKG	mean R amplitude, mean amplitude of signal measured from isoelectric line to peak of QRS	0.085728	0.042158	0.55684	0.309	0.0473
EKG	mean SR amplitude, mean amplitude of signal measured from signal minimum line to peak of QRS	0.10285	0.065269	0.50575	0.469	0.121
EKG	number of signals	-3.2599	4.0717	-0.71294	0.854	0.427
EKG	proportion of number pairs of successive beat-to-beat intervals that exceed 50 ms	-10.941	6.2408	-1.8570	0.782	0.0857
EKG	QT dispersion, measured as inter-lead variability of QT intervals	-3.7967	2.4109	-1.0701	0.858	0.122
EKG	QTc dispersion, calculated as rate-corrected QT dispersion	-2.7500	2.1758	-0.72861	0.860	0.212
EKG	root mean square of successive differences of neighboring RR intervals	-2.4150	1.4606	-1.2652	0.843	0.105
glucose tolerance test	amount glucose injected	-3.8057	2.2641	-0.73396	0.428	0.0993
glucose tolerance test	plasma glucose, 0min	4.6017	4.0197	0.23411	0.472	0.258
glucose tolerance test	plasma glucose, 15min	36.055	18.733	1.0993	0.286	0.0601
glucose tolerance test	plasma glucose, 30min	16.248	16.508	0.61782	0.653	0.330
glucose tolerance test	plasma glucose, 60min	-9.1553	9.5010	-0.26243	0.670	0.340
glucose tolerance test	plasma glucose, 120min	-2.2006	5.2865	-0.28809	0.876	0.679
grip strength	body weight (at time of grip strength test)	-0.31360	0.63222	-0.092972	0.772	0.624
grip strength	forelimb and hindlimb grip strength (mean of trials), average	-18.033	6.4643	-0.97596	0.0565	0.0104
grip strength	forelimb and hindlimb grip strength (mean of trials), average normalized to bw	-0.76887	0.30390	-0.90150	0.0855	0.0184
grip strength	forelimb and hindlimb grip strength by trial, trial1	-18.453	9.5803	-0.95742	0.262	0.0660
grip strength	forelimb and hindlimb grip strength by trial, trial2	-32.504	13.333	-1.7715	0.129	0.0226
grip strength	forelimb and hindlimb grip strength by trial, trial3	-14.996	8.9571	-0.77360	0.329	0.108
grip strength	forelimb grip strength (mean of trials), average	-3.3902	6.5173	-0.17664	0.819	0.608
grip strength	forelimb grip strength (mean of trials), average normalized to bw	-0.26088	0.30959	-0.43285	0.672	0.408
grip strength	forelimb grip strength by trial, trial1	-1.0002	9.6118	0.16632	0.970	0.918
grip strength	forelimb grip strength by trial, trial2	-14.174	9.0380	-1.2354	0.430	0.130
grip strength	forelimb grip strength by trial, trial3	-8.3058	11.363	-0.66088	0.754	0.472
light / dark	fecal boli count, 20 min test	1.9913	0.79065	1.9726	0.278	0.0151
light / dark	latency to enter dark zone, 20 min test	66.338	33.617	1.0696	0.431	0.0541
light / dark	number of transitions between light and dark zones, 20 min test	-2.1660	6.0257	-0.096141	0.889	0.721
light / dark	percentage of total time in dark zone, 20 min test	-5.3418	3.3901	-0.83356	0.473	0.121
light / dark	percentage of total time in light zone, 20 min test	5.3418	3.3901	0.83164	0.472	0.121
light / dark	time mobile in dark zone, 20 min test	-3.7637	10.604	-0.36198	0.885	0.724
light / dark	time mobile in light zone, 20 min test	10.364	11.384	0.41889	0.633	0.367
light / dark	time spent in dark zone, 20 min test	-105.19	42.359	-1.2526	0.216	0.0165
light / dark	time spent in light zone, 20 min test	105.19	42.359	1.2526	0.216	0.0165
open field	average speed in center of arena, 20 min test	-0.75761	0.45409	-1.5371	0.407	0.102
open field	average speed in periphery of arena, 20 min test	-0.061345	0.17087	-0.75020	0.852	0.721
open field	distance traveled habituation ratio, 20 min test	7.7491	9.4182	0.64900	0.714	0.415
open field	distance traveled in center of arena, 20 min test	71.598	95.836	0.11505	0.691	0.459
open field	distance traveled in periphery of arena, 20 min test	-117.13	161.97	-0.91345	0.697	0.473
open field	distance traveled slope, 20 min test	4.4437	8.9864	0.42386	0.845	0.623
open field	distance traveled, 20 min test, 1st 5min	-101.94	110.10	-1.1231	0.603	0.359
open field	distance traveled, 20 min test, 2nd 5min	54.225	56.384	0.097492	0.587	0.341
open field	distance traveled, 20 min test, 3rd 5min	-19.781	56.108	-0.66734	0.875	0.726
open field	distance traveled, 20 min test, 4th 5min	-38.726	52.282	-0.90735	0.696	0.462
open field	number of clockwise revolution episodes, 20 min test	-0.28852	1.2149	-0.58042	0.932	0.813
open field	number of counter-clockwise revolution episodes, 20 min test	-1.6357	1.2927	-1.3086	0.501	0.212
open field	number of fecal boli, 20 min test	1.7082	0.93921	1.4808	0.323	0.0751
open field	number of rears in 5 min bins, 20 min test, 1st 5min	-3.0087	2.4544	-1.0180	0.494	0.226
open field	number of rears in 5 min bins, 20 min test, 2nd 5min	1.3026	2.6270	-0.034243	0.814	0.622
open field	number of rears in 5 min bins, 20 min test, 3rd 5min	1.6378	2.7008	0.075930	0.761	0.547
open field	number of rears in 5 min bins, 20 min test, 4th 5min	1.1449	2.7748	-0.11099	0.840	0.682
open field	percentage of total time in center of arena, 20 min test	2.4209	2.7868	0.34435	0.694	0.389
open field	percentage of total time in center of arena, slope, 20 min test	2.2118	1.6257	1.3508	0.647	0.180
open field	percentage of total time in center, habituation ratio, 20 min test	1.6236	1.7528	0.97856	0.800	0.359
open field	percentage of total time in corners of arena, 20 min test	-7.7200	4.6137	-1.1410	0.387	0.101
open field	percentage of total time in corners, habituation ratio, 20 min test	1.7415	2.4335	0.51074	0.874	0.478
open field	percentage of total time in corners, slope, 20 min test	1.2566	2.3369	0.30191	0.911	0.593
open field	permanence time in center of arena, 20 min test	29.049	33.439	0.34292	0.694	0.389
open field	permanence time in corners of arena, 20 min test	-92.663	55.367	-1.1410	0.387	0.101
open field	permanence time in periphery of arena, 20 min test	-29.121	33.443	-0.34577	0.693	0.388
open field	total distance traveled, 20 min test	-38.058	224.48	-0.61296	0.933	0.866
open field	total number of rears, 20 min test	1.0765	9.2518	-0.27113	0.960	0.908
open field	whole arena average speed, 20 min test	-0.029944	0.18702	-0.60649	0.933	0.873
open field	whole arena resting time, 20 min test	-4.1886	20.785	0.46088	0.906	0.841
open field	whole arena time spent mobile, 20 min test	4.0900	20.786	-0.35291	0.914	0.845
open field	whole arena time spent vertical, 20 min test	-2.1081	7.9972	-0.28090	0.919	0.793
plasma chemistry analysis	free fatty acids (plasma)	0.015137	0.072680	0.84793	0.877	0.836
plasma chemistry analysis	plasma cholesterol	-0.94485	3.0378	0.11621	0.830	0.757
plasma chemistry analysis	plasma glucose (4h fast)	2.5276	6.7864	0.92990	0.853	0.711
plasma chemistry analysis	plasma HDL	-1.4415	2.8817	-0.26248	0.794	0.618
plasma chemistry analysis	plasma triglycerides (4h fast)	5.5368	4.4478	1.1975	0.412	0.217
rotarod	learning difference on accelerating rotarod (4-40 rpm/5 min) over 5 trials	13.336	8.2186	1.2594	0.653	0.111
rotarod	learning slope on accelerating rotarod (4-40 rpm/5 min) over 5 trials	4.6260	2.6826	1.4376	0.631	0.0907
rotarod	mean duration on accelerating rotarod (4-40 rpm/5 min) over 5 trials	-0.37366	6.1992	0.25892	0.989	0.952
rotarod	mean latency to fall off accelerating rotarod (4-40 rpm/ 5 min) over 5 trials	26.104	14.124	1.8740	0.491	0.0705
SHIRPA	locomotor activity (number of squares in the arena the mouse moves into with all four paws in first 30 s of test)	-1.0271	2.2741	-0.24939	0.856	0.656
startle / PPI	average baseline movement during background noise	-0.15226	0.26099	-0.039943	0.906	0.563
startle / PPI	average of each corrected maximum percent pre-pulse inhibition value	0.14101	0.068280	1.1279	0.289	0.0448
startle / PPI	average of each corrected percent pre-pulse inhibition value	0.15821	0.066476	1.4240	0.218	0.0217
startle / PPI	average of maximum percent pre-pulse inhibition for each pre-pulse tested	9.8294	6.3692	0.94326	0.427	0.130
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	10.263	7.3536	1.1685	0.843	0.170
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	15.704	6.4365	1.6052	0.245	0.0188
startle / PPI	average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	8.9599	5.9489	0.81751	0.411	0.139
startle / PPI	average startle response to full pulse (120 dB)	-30.693	9.9520	-0.40372	0.0315	0.00352
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-26.565	9.2720	-0.35404	0.0447	0.00637
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-26.864	8.7905	-0.37801	0.0310	0.00380
startle / PPI	average startle response to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-20.088	8.2240	-0.30375	0.0942	0.0187
startle / PPI	average startle response to pre-pulse, 74dB sound pressure level	0.096549	0.31862	0.15829	0.964	0.763
startle / PPI	average startle response to pre-pulse, 78dB sound pressure level	0.18890	0.51451	0.13987	0.951	0.715
startle / PPI	average startle response to pre-pulse, 82dB sound pressure level	0.73245	0.49532	0.18245	0.588	0.146
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	0.13183	0.078504	1.2844	0.782	0.100
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	0.19525	0.073350	1.5749	0.171	0.0108
startle / PPI	corrected average percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	0.15145	0.069872	0.96966	0.171	0.0356
startle / PPI	corrected average startle response to full pulse (120 dB) minus average baseline movement during background noise	-30.541	9.9599	-0.39159	0.0331	0.00370
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 74dB sound pressure level	-26.680	9.3483	-0.35553	0.0445	0.00656
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 78dB sound pressure level	-27.132	8.9145	-0.36600	0.0316	0.00394
startle / PPI	corrected average startle response to pre-pulse and full pulse (120 dB) minus average startle response to same pre-pulse, 82dB sound pressure level	-20.853	8.4095	-0.30668	0.0886	0.0170
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	0.11606	0.086989	1.0253	0.821	0.189
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	0.18112	0.074932	1.3439	0.206	0.0199
startle / PPI	corrected maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	0.13109	0.072236	0.75971	0.259	0.0764
startle / PPI	corrected maximum startle response to full pulse (120 dB) minus maximum baseline movement during background noise	-143.95	43.239	-0.53036	0.0183	0.00177
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 74dB sound pressure level	-118.90	40.815	-0.45287	0.0404	0.00560
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 78dB sound pressure level	-114.42	38.419	-0.44048	0.0359	0.00470
startle / PPI	corrected maximum startle response to pre-pulse and full pulse (120 dB) minus maximum startle response to same pre-pulse, 82dB sound pressure level	-83.454	35.848	-0.34213	0.114	0.0246
startle / PPI	maximum baseline movement during background noise	-0.46896	0.80024	-0.031531	0.874	0.561
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	8.4272	8.1575	0.86338	0.888	0.307
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	14.408	6.8301	1.2562	0.309	0.0406
startle / PPI	maximum percent pre-pulse inhibition to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	6.5507	6.1898	0.47942	0.584	0.296
startle / PPI	maximum startle response to full pulse (120 dB)	-144.43	43.231	-0.53359	0.0180	0.00171
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 74dB sound pressure level	-117.95	40.662	-0.45287	0.0407	0.00579
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 78dB sound pressure level	-114.16	38.195	-0.44203	0.0346	0.00457
startle / PPI	maximum startle response to full pulse (120 dB) preceded by pre-pulse, 82dB sound pressure level	-81.513	35.306	-0.34659	0.118	0.0257
startle / PPI	maximum startle response to pre-pulse, 74dB sound pressure level	0.94818	1.1253	0.43740	0.799	0.404
startle / PPI	maximum startle response to pre-pulse, 78dB sound pressure level	0.20159	1.2582	0.080653	0.980	0.873
startle / PPI	maximum startle response to pre-pulse, 82dB sound pressure level	1.7087	1.3274	0.14553	0.588	0.205
tail suspension	duration of immobility, 5 min test	3.2315	12.672	-0.41951	0.904	0.800
tail suspension	latency to immobility, 5 min test	-1.3298	1.0972	-0.34504	0.725	0.231

MULTIPLE (CATEGORICAL) TRAIT PROFILE PLOT — Early Adult Phenotyping study (EAP)

In this plot, data points are the computed genotype effect % vs. C57BL/6NJ controls, for all measured categorical phenotypes in JaxKOMP-EAP

Dimensions Width: × Height: px

Plot Options Group by Procedure

Include Sexes Data Both Females Males

Significance Threshold p-Value Threshold

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Procedure	JaxKOMP-EAP Trait	Sex	Trait Effect	P-value

eye morphology	bulging eye	females	1.0 %	1.0
eye morphology	bulging eye	males	0.0 %	1.0
eye morphology	bulging eye	both	1.0 %	1.00
eye morphology	cornea	females	4.0 %	1.0
eye morphology	cornea	males	2.0 %	1.0
eye morphology	cornea	both	3.0 %	1.00
eye morphology	cornea opacity	females	5.0 %	1.00
eye morphology	cornea opacity	males	1.0 %	1.0
eye morphology	cornea opacity	both	3.0 %	1.00
eye morphology	cornea vascularization	females	3.0 %	1.0
eye morphology	cornea vascularization	males	1.0 %	1.0
eye morphology	cornea vascularization	both	2.0 %	1.00
eye morphology	corneal deposits	females	2.0 %	1.0
eye morphology	corneal deposits	males	12.0 %	0.0473
eye morphology	corneal deposits	both	6.0 %	0.136
eye morphology	corneal mineralization	females	2.0 %	1.0
eye morphology	corneal mineralization	males	1.0 %	1.0
eye morphology	corneal mineralization	both	1.0 %	1.00
eye morphology	corneal scleralization	females	3.0 %	1.00
eye morphology	corneal scleralization	males	1.0 %	1.0
eye morphology	corneal scleralization	both	2.0 %	1.00
eye morphology	corneal ulcer	females	1.0 %	1.0
eye morphology	corneal ulcer	males	1.0 %	1.0
eye morphology	corneal ulcer	both	1.0 %	1.00
eye morphology	eye closure	females	1.0 %	1.00
eye morphology	eye closure	males	0.0 %	1.0
eye morphology	eye closure	both	1.0 %	1.0
eye morphology	eye hemorrhage or blood presence	females	2.0 %	1.00
eye morphology	eye hemorrhage or blood presence	males	1.0 %	1.0
eye morphology	eye hemorrhage or blood presence	both	1.0 %	1.00
eye morphology	eyelid morphology	females	1.0 %	1.0
eye morphology	eyelid morphology	males	0.0 %	1.0
eye morphology	eyelid morphology	both	1.0 %	1.0
eye morphology	eyes (present, absent)	females	1.0 %	1.0
eye morphology	eyes (present, absent)	males	0.0 %	1.0
eye morphology	eyes (present, absent)	both	0.0 %	1.0
eye morphology	fusion between cornea and lens	females	4.0 %	1.00
eye morphology	fusion between cornea and lens	males	2.0 %	1.0
eye morphology	fusion between cornea and lens	both	3.0 %	1.00
eye morphology	iris pigmentation	females	2.0 %	1.0
eye morphology	iris pigmentation	males	1.0 %	1.0
eye morphology	iris pigmentation	both	2.0 %	1.00
eye morphology	iris transillumination	females	2.0 %	1.00
eye morphology	iris transillumination	males	1.0 %	1.0
eye morphology	iris transillumination	both	1.0 %	1.00
eye morphology	irispupil	females	4.0 %	1.00
eye morphology	irispupil	males	12.0 %	0.127
eye morphology	irispupil	both	5.0 %	0.301
eye morphology	lacrimation	females	3.0 %	1.0
eye morphology	lacrimation	males	2.0 %	1.0
eye morphology	lacrimation	both	3.0 %	1.00
eye morphology	lens	females	22.0 %	0.131
eye morphology	lens	males	29.0 %	0.0385
eye morphology	lens	both	22.0 %	0.0305
eye morphology	lens opacity	females	9.0 %	1.0
eye morphology	lens opacity	males	6.0 %	1.0
eye morphology	lens opacity	both	7.0 %	1.00
eye morphology	narrow eye opening	females	2.0 %	1.0
eye morphology	narrow eye opening	males	1.0 %	1.0
eye morphology	narrow eye opening	both	1.0 %	1.0
eye morphology	optic disc	females	4.0 %	1.00
eye morphology	optic disc	males	2.0 %	1.0
eye morphology	optic disc	both	3.0 %	1.00
eye morphology	persistence of hyaloid vascular system	females	14.0 %	1.0
eye morphology	persistence of hyaloid vascular system	males	5.0 %	1.0
eye morphology	persistence of hyaloid vascular system	both	9.0 %	1.00
eye morphology	pupil dilation	females	2.0 %	1.0
eye morphology	pupil dilation	males	1.0 %	1.0
eye morphology	pupil dilation	both	2.0 %	1.0
eye morphology	pupil light response	females	2.0 %	1.00
eye morphology	pupil light response	males	1.0 %	1.0
eye morphology	pupil light response	both	2.0 %	1.00
eye morphology	pupil position	females	11.0 %	0.301
eye morphology	pupil position	males	12.0 %	0.128
eye morphology	pupil position	both	9.0 %	0.140
eye morphology	pupil shape	females	3.0 %	1.00
eye morphology	pupil shape	males	12.0 %	0.0878
eye morphology	pupil shape	both	6.0 %	0.133
eye morphology	retina	females	10.0 %	0.560
eye morphology	retina	males	7.0 %	0.610
eye morphology	retina	both	2.0 %	0.721
eye morphology	retinal blood vessels	females	4.0 %	1.0
eye morphology	retinal blood vessels	males	2.0 %	1.0
eye morphology	retinal blood vessels	both	3.0 %	1.0
eye morphology	retinal blood vessels pattern	females	5.0 %	1.0
eye morphology	retinal blood vessels pattern	males	2.0 %	1.0
eye morphology	retinal blood vessels pattern	both	4.0 %	1.00
eye morphology	retinal blood vessels structure	females	21.0 %	0.000779
eye morphology	retinal blood vessels structure	males	2.0 %	1.0
eye morphology	retinal blood vessels structure	both	9.0 %	0.00354
eye morphology	retinal pigmentation	females	21.0 %	0.228
eye morphology	retinal pigmentation	males	86.0 %	6.99e-8
eye morphology	retinal pigmentation	both	52.0 %	0.00000147
eye morphology	retinal structure	females	4.0 %	1.00
eye morphology	retinal structure	males	2.0 %	1.0
eye morphology	retinal structure	both	3.0 %	1.00
eye morphology	synechia	females	4.0 %	1.0
eye morphology	synechia	males	2.0 %	1.0
eye morphology	synechia	both	3.0 %	1.00
eye morphology	vitreous	females	12.0 %	0.0222
eye morphology	vitreous	males	2.0 %	1.0
eye morphology	vitreous	both	6.0 %	0.0222
rotarod	outcome of accelerating rotarod (4-40 rpm/ 5 min) over 5 trials	females	0.0 %	1.0
rotarod	outcome of accelerating rotarod (4-40 rpm/ 5 min) over 5 trials	males	0.0 %	1.0
rotarod	outcome of accelerating rotarod (4-40 rpm/ 5 min) over 5 trials	both	0.0 %	1.0
rotarod	trial number	females	0.0 %	1.0
rotarod	trial number	males	0.0 %	1.0
rotarod	trial number	both	0.0 %	1.0
SHIRPA	activity body position	females	1.0 %	1.0
SHIRPA	activity body position	males	2.0 %	1.0
SHIRPA	activity body position	both	1.0 %	1.00
SHIRPA	aggression	females	0.0 %	1.00
SHIRPA	aggression	males	1.0 %	1.0
SHIRPA	aggression	both	1.0 %	1.0
SHIRPA	body length	females	0.0 %	1.0
SHIRPA	body length	males	0.0 %	1.00
SHIRPA	body length	both	0.0 %	1.00
SHIRPA	body position	females	0.0 %	1.0
SHIRPA	body position	males	1.0 %	1.0
SHIRPA	body position	both	0.0 %	1.0
SHIRPA	body thickness	females	1.0 %	1.0
SHIRPA	body thickness	males	0.0 %	1.0
SHIRPA	body thickness	both	0.0 %	1.0
SHIRPA	coat color abdomen	females	9.0 %	0.250
SHIRPA	coat color abdomen	males	9.0 %	0.256
SHIRPA	coat color abdomen	both	9.0 %	0.110
SHIRPA	coat color back	females	12.0 %	0.0146
SHIRPA	coat color back	males	12.0 %	0.0147
SHIRPA	coat color back	both	12.0 %	0.000362
SHIRPA	coat color head	females	12.0 %	0.00587
SHIRPA	coat color head	males	12.0 %	0.0147
SHIRPA	coat color head	both	12.0 %	0.000170
SHIRPA	coat color pattern abdomen	females	12.0 %	0.0461
SHIRPA	coat color pattern abdomen	males	12.0 %	0.0550
SHIRPA	coat color pattern abdomen	both	12.0 %	0.00459
SHIRPA	coat color pattern back	females	0.0 %	1.0
SHIRPA	coat color pattern back	males	0.0 %	1.00
SHIRPA	coat color pattern back	both	0.0 %	1.0
SHIRPA	coat color pattern head	females	0.0 %	1.0
SHIRPA	coat color pattern head	males	0.0 %	1.0
SHIRPA	coat color pattern head	both	0.0 %	1.00
SHIRPA	coat hair abdomen texture appearance	females	2.0 %	1.0
SHIRPA	coat hair abdomen texture appearance	males	2.0 %	1.0
SHIRPA	coat hair abdomen texture appearance	both	2.0 %	1.0
SHIRPA	coat hair back texture appearance	females	0.0 %	1.0
SHIRPA	coat hair back texture appearance	males	0.0 %	1.0
SHIRPA	coat hair back texture appearance	both	0.0 %	1.0
SHIRPA	coat hair distribution abdomen	females	0.0 %	1.0
SHIRPA	coat hair distribution abdomen	males	1.0 %	1.00
SHIRPA	coat hair distribution abdomen	both	1.0 %	1.00
SHIRPA	coat hair distribution back	females	0.0 %	1.0
SHIRPA	coat hair distribution back	males	0.0 %	1.0
SHIRPA	coat hair distribution back	both	0.0 %	1.0
SHIRPA	coat hair distribution head	females	1.0 %	1.00
SHIRPA	coat hair distribution head	males	1.0 %	1.0
SHIRPA	coat hair distribution head	both	1.0 %	1.0
SHIRPA	coat hair head texture appearance	females	0.0 %	1.00
SHIRPA	coat hair head texture appearance	males	0.0 %	1.0
SHIRPA	coat hair head texture appearance	both	0.0 %	1.0
SHIRPA	contact righting	females	5.0 %	1.0
SHIRPA	contact righting	males	5.0 %	1.00
SHIRPA	contact righting	both	5.0 %	1.00
SHIRPA	ear morphology	females	0.0 %	1.0
SHIRPA	ear morphology	males	0.0 %	1.0
SHIRPA	ear morphology	both	0.0 %	1.0
SHIRPA	fat distribution	females	0.0 %	1.0
SHIRPA	fat distribution	males	0.0 %	1.0
SHIRPA	fat distribution	both	0.0 %	1.00
SHIRPA	forelimb digit number	females	0.0 %	1.00
SHIRPA	forelimb digit number	males	0.0 %	1.0
SHIRPA	forelimb digit number	both	0.0 %	1.00
SHIRPA	forelimb digit position	females	0.0 %	1.0
SHIRPA	forelimb digit position	males	0.0 %	1.0
SHIRPA	forelimb digit position	both	0.0 %	1.0
SHIRPA	forelimb digit shape	females	0.0 %	1.0
SHIRPA	forelimb digit shape	males	0.0 %	1.0
SHIRPA	forelimb digit shape	both	0.0 %	1.0
SHIRPA	forelimb digit size	females	0.0 %	1.0
SHIRPA	forelimb digit size	males	0.0 %	1.0
SHIRPA	forelimb digit size	both	0.0 %	1.0
SHIRPA	forelimb footpads	females	0.0 %	1.0
SHIRPA	forelimb footpads	males	0.0 %	1.0
SHIRPA	forelimb footpads	both	0.0 %	1.0
SHIRPA	forelimb nail length	females	0.0 %	1.0
SHIRPA	forelimb nail length	males	0.0 %	1.0
SHIRPA	forelimb nail length	both	0.0 %	1.0
SHIRPA	forelimb nail number	females	0.0 %	1.0
SHIRPA	forelimb nail number	males	0.0 %	1.0
SHIRPA	forelimb nail number	both	0.0 %	1.0
SHIRPA	forelimb nail position	females	0.0 %	1.0
SHIRPA	forelimb nail position	males	0.0 %	1.0
SHIRPA	forelimb nail position	both	0.0 %	1.0
SHIRPA	forelimb nail shape	females	0.0 %	1.0
SHIRPA	forelimb nail shape	males	0.0 %	1.0
SHIRPA	forelimb nail shape	both	0.0 %	1.0
SHIRPA	forelimbs position	females	0.0 %	1.0
SHIRPA	forelimbs position	males	0.0 %	1.0
SHIRPA	forelimbs position	both	0.0 %	1.0
SHIRPA	forelimbs shape	females	0.0 %	1.0
SHIRPA	forelimbs shape	males	0.0 %	1.0
SHIRPA	forelimbs shape	both	0.0 %	1.0
SHIRPA	forelimbs size	females	0.0 %	1.0
SHIRPA	forelimbs size	males	0.0 %	1.0
SHIRPA	forelimbs size	both	0.0 %	1.0
SHIRPA	forepaw position	females	0.0 %	1.0
SHIRPA	forepaw position	males	0.0 %	1.0
SHIRPA	forepaw position	both	0.0 %	1.0
SHIRPA	forepaw shape	females	0.0 %	1.0
SHIRPA	forepaw shape	males	0.0 %	1.0
SHIRPA	forepaw shape	both	0.0 %	1.0
SHIRPA	forepaw size	females	0.0 %	1.0
SHIRPA	forepaw size	males	0.0 %	1.0
SHIRPA	forepaw size	both	0.0 %	1.0
SHIRPA	gait (fluidity)	females	0.0 %	1.0
SHIRPA	gait (fluidity)	males	0.0 %	1.00
SHIRPA	gait (fluidity)	both	0.0 %	1.00
SHIRPA	genitalia morphology	females	0.0 %	1.00
SHIRPA	genitalia morphology	males	0.0 %	1.0
SHIRPA	genitalia morphology	both	0.0 %	1.00
SHIRPA	genitalia presence	females	0.0 %	1.0
SHIRPA	genitalia presence	males	0.0 %	1.0
SHIRPA	genitalia presence	both	0.0 %	1.0
SHIRPA	genitalia size	females	0.0 %	1.0
SHIRPA	genitalia size	males	0.0 %	1.0
SHIRPA	genitalia size	both	0.0 %	1.0
SHIRPA	head bobbing	females	0.0 %	1.0
SHIRPA	head bobbing	males	0.0 %	1.0
SHIRPA	head bobbing	both	0.0 %	1.0
SHIRPA	head morphology	females	0.0 %	1.0
SHIRPA	head morphology	males	0.0 %	1.00
SHIRPA	head morphology	both	0.0 %	1.0
SHIRPA	head size	females	0.0 %	1.0
SHIRPA	head size	males	0.0 %	1.0
SHIRPA	head size	both	0.0 %	1.00
SHIRPA	hindlimb digit number	females	1.0 %	1.00
SHIRPA	hindlimb digit number	males	0.0 %	1.0
SHIRPA	hindlimb digit number	both	0.0 %	1.00
SHIRPA	hindlimb digit position	females	0.0 %	1.0
SHIRPA	hindlimb digit position	males	0.0 %	1.0
SHIRPA	hindlimb digit position	both	0.0 %	1.0
SHIRPA	hindlimb digit shape	females	0.0 %	1.0
SHIRPA	hindlimb digit shape	males	0.0 %	1.0
SHIRPA	hindlimb digit shape	both	0.0 %	1.0
SHIRPA	hindlimb digit size	females	0.0 %	1.00
SHIRPA	hindlimb digit size	males	0.0 %	1.0
SHIRPA	hindlimb digit size	both	0.0 %	1.00
SHIRPA	hindlimb nail length	females	0.0 %	1.0
SHIRPA	hindlimb nail length	males	0.0 %	1.0
SHIRPA	hindlimb nail length	both	0.0 %	1.00
SHIRPA	hindlimb nail number	females	0.0 %	1.0
SHIRPA	hindlimb nail number	males	1.0 %	1.0
SHIRPA	hindlimb nail number	both	0.0 %	1.00
SHIRPA	hindlimb nail position	females	0.0 %	1.0
SHIRPA	hindlimb nail position	males	0.0 %	1.0
SHIRPA	hindlimb nail position	both	0.0 %	1.0
SHIRPA	hindlimb nail shape	females	0.0 %	1.0
SHIRPA	hindlimb nail shape	males	0.0 %	1.0
SHIRPA	hindlimb nail shape	both	0.0 %	1.0
SHIRPA	hindlimbs footpads	females	0.0 %	1.0
SHIRPA	hindlimbs footpads	males	0.0 %	1.0
SHIRPA	hindlimbs footpads	both	0.0 %	1.0
SHIRPA	hindlimbs position	females	0.0 %	1.0
SHIRPA	hindlimbs position	males	0.0 %	1.0
SHIRPA	hindlimbs position	both	0.0 %	1.0
SHIRPA	hindlimbs shape	females	0.0 %	1.0
SHIRPA	hindlimbs shape	males	0.0 %	1.0
SHIRPA	hindlimbs shape	both	0.0 %	1.0
SHIRPA	hindlimbs size	females	0.0 %	1.0
SHIRPA	hindlimbs size	males	0.0 %	1.0
SHIRPA	hindlimbs size	both	0.0 %	1.0
SHIRPA	hindpaw position	females	0.0 %	1.0
SHIRPA	hindpaw position	males	0.0 %	1.0
SHIRPA	hindpaw position	both	0.0 %	1.0
SHIRPA	hindpaw shape	females	0.0 %	1.0
SHIRPA	hindpaw shape	males	0.0 %	1.0
SHIRPA	hindpaw shape	both	0.0 %	1.0
SHIRPA	hindpaw size	females	0.0 %	1.0
SHIRPA	hindpaw size	males	0.0 %	1.0
SHIRPA	hindpaw size	both	0.0 %	1.0
SHIRPA	limb grasp	females	4.0 %	0.524
SHIRPA	limb grasp	males	6.0 %	1.0
SHIRPA	limb grasp	both	1.0 %	1.0
SHIRPA	lower lip morphology	females	0.0 %	1.0
SHIRPA	lower lip morphology	males	0.0 %	1.0
SHIRPA	lower lip morphology	both	0.0 %	1.0
SHIRPA	lower teeth appearance	females	0.0 %	1.0
SHIRPA	lower teeth appearance	males	0.0 %	1.00
SHIRPA	lower teeth appearance	both	0.0 %	1.00
SHIRPA	mouth morphology	females	0.0 %	1.0
SHIRPA	mouth morphology	males	0.0 %	1.00
SHIRPA	mouth morphology	both	0.0 %	1.00
SHIRPA	salivation	females	0.0 %	1.0
SHIRPA	salivation	males	0.0 %	1.0
SHIRPA	salivation	both	0.0 %	1.0
SHIRPA	skin color back paws	females	0.0 %	1.0
SHIRPA	skin color back paws	males	0.0 %	1.0
SHIRPA	skin color back paws	both	0.0 %	1.0
SHIRPA	skin color ear	females	0.0 %	1.0
SHIRPA	skin color ear	males	0.0 %	1.0
SHIRPA	skin color ear	both	0.0 %	1.0
SHIRPA	skin color front paws	females	0.0 %	1.0
SHIRPA	skin color front paws	males	0.0 %	1.0
SHIRPA	skin color front paws	both	0.0 %	1.0
SHIRPA	skin color snout	females	0.0 %	1.0
SHIRPA	skin color snout	males	0.0 %	1.0
SHIRPA	skin color snout	both	0.0 %	1.0
SHIRPA	skin color tail	females	0.0 %	1.0
SHIRPA	skin color tail	males	0.0 %	1.0
SHIRPA	skin color tail	both	0.0 %	1.0
SHIRPA	skin color whole body	females	0.0 %	1.0
SHIRPA	skin color whole body	males	0.0 %	1.0
SHIRPA	skin color whole body	both	0.0 %	1.0
SHIRPA	skin texture back paw	females	0.0 %	1.0
SHIRPA	skin texture back paw	males	0.0 %	1.0
SHIRPA	skin texture back paw	both	0.0 %	1.0
SHIRPA	skin texture ear	females	0.0 %	1.0
SHIRPA	skin texture ear	males	0.0 %	1.0
SHIRPA	skin texture ear	both	0.0 %	1.0
SHIRPA	skin texture front paws	females	0.0 %	1.0
SHIRPA	skin texture front paws	males	0.0 %	1.0
SHIRPA	skin texture front paws	both	0.0 %	1.0
SHIRPA	skin texture snout	females	0.0 %	1.0
SHIRPA	skin texture snout	males	0.0 %	1.0
SHIRPA	skin texture snout	both	0.0 %	1.0
SHIRPA	skin texture tail	females	0.0 %	1.0
SHIRPA	skin texture tail	males	0.0 %	1.0
SHIRPA	skin texture tail	both	0.0 %	1.0
SHIRPA	skin texture whole body	females	0.0 %	1.0
SHIRPA	skin texture whole body	males	0.0 %	1.00
SHIRPA	skin texture whole body	both	0.0 %	1.00
SHIRPA	snout size	females	0.0 %	1.0
SHIRPA	snout size	males	12.0 %	0.0436
SHIRPA	snout size	both	6.0 %	0.0575
SHIRPA	startle response	females	0.0 %	1.00
SHIRPA	startle response	males	0.0 %	1.00
SHIRPA	startle response	both	0.0 %	1.00
SHIRPA	tail curvature	females	0.0 %	1.00
SHIRPA	tail curvature	males	0.0 %	1.0
SHIRPA	tail curvature	both	0.0 %	1.0
SHIRPA	tail elevation	females	1.0 %	1.00
SHIRPA	tail elevation	males	2.0 %	1.0
SHIRPA	tail elevation	both	1.0 %	1.0
SHIRPA	tail length	females	0.0 %	1.0
SHIRPA	tail length	males	0.0 %	1.0
SHIRPA	tail length	both	0.0 %	1.00
SHIRPA	tail morphology	females	0.0 %	1.00
SHIRPA	tail morphology	males	0.0 %	1.0
SHIRPA	tail morphology	both	0.0 %	1.00
SHIRPA	tail presence	females	0.0 %	1.0
SHIRPA	tail presence	males	0.0 %	1.0
SHIRPA	tail presence	both	0.0 %	1.0
SHIRPA	tail shape	females	0.0 %	1.0
SHIRPA	tail shape	males	0.0 %	1.0
SHIRPA	tail shape	both	0.0 %	1.00
SHIRPA	tail thickness	females	0.0 %	1.0
SHIRPA	tail thickness	males	0.0 %	1.0
SHIRPA	tail thickness	both	0.0 %	1.0
SHIRPA	teeth presence	females	0.0 %	1.0
SHIRPA	teeth presence	males	0.0 %	1.00
SHIRPA	teeth presence	both	0.0 %	1.00
SHIRPA	touch escape	females	14.0 %	0.606
SHIRPA	touch escape	males	14.0 %	0.611
SHIRPA	touch escape	both	14.0 %	0.161
SHIRPA	transfer arousal	females	1.0 %	1.0
SHIRPA	transfer arousal	males	2.0 %	1.00
SHIRPA	transfer arousal	both	1.0 %	1.0
SHIRPA	tremor	females	0.0 %	1.0
SHIRPA	tremor	males	0.0 %	1.0
SHIRPA	tremor	both	0.0 %	1.00
SHIRPA	trunk curl	females	0.0 %	1.00
SHIRPA	trunk curl	males	0.0 %	1.0
SHIRPA	trunk curl	both	0.0 %	1.0
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	females	0.0 %	1.0
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	males	0.0 %	1.0
SHIRPA	unexpected behaviors (circling, head bobbing, jumping, retropulsion)	both	0.0 %	1.00
SHIRPA	upper lip morphology	females	0.0 %	1.0
SHIRPA	upper lip morphology	males	0.0 %	1.0
SHIRPA	upper lip morphology	both	0.0 %	1.0
SHIRPA	upper teeth appearance	females	0.0 %	1.0
SHIRPA	upper teeth appearance	males	0.0 %	1.0
SHIRPA	upper teeth appearance	both	0.0 %	1.00
SHIRPA	vibrissae appearance	females	2.0 %	1.0
SHIRPA	vibrissae appearance	males	1.0 %	1.0
SHIRPA	vibrissae appearance	both	1.0 %	1.0
SHIRPA	vibrissae presence	females	2.0 %	1.00
SHIRPA	vibrissae presence	males	1.0 %	1.0
SHIRPA	vibrissae presence	both	2.0 %	1.0
SHIRPA	vocalization	females	2.0 %	1.00
SHIRPA	vocalization	males	2.0 %	1.0
SHIRPA	vocalization	both	2.0 %	1.00
tail suspension	climbing, 5 min test (yes, no)	females	22.0 %	0.213
tail suspension	climbing, 5 min test (yes, no)	males	22.0 %	0.357
tail suspension	climbing, 5 min test (yes, no)	both	22.0 %	0.0520

GENOTYPE CORRELATION PLOT

Correlate Dixdc1^{tm1.1(KOMP)Vlcg} -/+ with genotype: