ITP phenotypes:   body weight     Protandim

Trial code: Prot Dose: 600 ppm then 1200 ppm   initiated at age: 10 mo then 17 mo Sex: f Cohort: C2011
Trial code: Prot Dose: 600 ppm then 1200 ppm   initiated at age: 10 mo then 17 mo Sex: m Cohort: C2011
The plots below show the means with ± SEM error bars





ANOVA

Factor Df Sum Sq Mean Sq F value Pr(>F)
group 1 696.9874 696.9874 4.7769 0.029
time 3 31327.4398 10442.4799 71.5685 < 0.0001
group:time 3 113.0071 37.669 0.2582 0.8555
Residuals 1552 226450.5976 145.9089 NA NA


Means

group time mean SE
Control time_m12 39.0436 0.5318
Control time_m18 42.8495 0.609
Control time_m24 41.7939 0.6595
Control time_m6 31.3862 1.2574
Prot time_m12 38.1462 0.7069
Prot time_m18 40.4802 0.7811
Prot time_m24 40.5086 0.8304
Prot time_m6 29.4635 0.5494


Pairwise comparisons (Tukey multiple-test correction)

contrast time estimate SE df t.ratio p.value
Control - Prot time_m6 1.9228 1.3407 1552 1.4342 0.1517
Control - Prot time_m12 0.8973 1.2703 1552 0.7064 0.4801
Control - Prot time_m18 2.3693 1.2765 1552 1.8561 0.0636
Control - Prot time_m24 1.2854 1.4217 1552 0.9041 0.3661










ANOVA

Factor Df Sum Sq Mean Sq F value Pr(>F)
group 1 143.8548 143.8548 3.7114 0.0542
time 3 8102.349 2700.783 69.6789 < 0.0001
group:time 3 269.4375 89.8125 2.3171 0.0739
Residuals 1454 56357.6195 38.7604 NA NA


Means

group time mean SE
Control time_m12 45.1358 0.3568
Control time_m18 44.6654 0.401
Control time_m24 40.5988 0.5568
Control time_m6 39.2211 0.3751
Prot time_m12 43.7483 0.5226
Prot time_m18 43.3352 0.541
Prot time_m24 41.5263 0.6399
Prot time_m6 39.0889 0.4782


Pairwise comparisons (Tukey multiple-test correction)

contrast time estimate SE df t.ratio p.value
Control - Prot time_m6 0.1322 0.6463 1454 0.2045 0.838
Control - Prot time_m12 1.3876 0.6374 1454 2.177 0.0296
Control - Prot time_m18 1.3302 0.6829 1454 1.9479 0.0516
Control - Prot time_m24 -0.9274 0.788 1454 -1.177 0.2394










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