ITP phenotypes:   body weight     nicotinamide riboside

Trial code: NR Dose: 1000 ppm   initiated at age: 8 mo Sex: f Cohort: C2016
Trial code: NR Dose: 1000 ppm   initiated at age: 8 mo Sex: m Cohort: C2016
The plots below show the means with ± SEM error bars





ANOVA

Factor Df Sum Sq Mean Sq F value Pr(>F)
group 1 212.1786 212.1786 3.0349 0.0818
time 3 26120.1174 8706.7058 124.5356 < 0.0001
group:time 3 104.853 34.951 0.4999 0.6824
Residuals 1123 78512.7614 69.9134 NA NA


Means

group time mean SE
Control time_m12 41.4571 0.5573
Control time_m18 45.6604 0.6419
Control time_m24 44.8555 0.7746
Control time_m6 33.1995 0.4124
NR time_m12 40.2632 0.8759
NR time_m18 44.3821 0.9944
NR time_m24 43.2803 1.1434
NR time_m6 33.3529 0.6029


Pairwise comparisons (Tukey multiple-test correction)

comparison time estimate SE df t.ratio p.value
Control - NR time_m6 -0.1533 1.0646 1123 -0.144 0.8855
Control - NR time_m12 1.1939 1.0661 1123 1.1199 0.263
Control - NR time_m18 1.2782 1.0817 1123 1.1817 0.2376
Control - NR time_m24 1.5752 1.1785 1123 1.3366 0.1816










ANOVA

Factor Df Sum Sq Mean Sq F value Pr(>F)
group 1 0.6218 0.6218 0.0136 0.9071
time 3 9647.44 3215.8133 70.4261 < 0.0001
group:time 3 190.8829 63.6276 1.3934 0.243
Residuals 1951 89087.0102 45.6622 NA NA


Means

group time mean SE
Control time_m12 45.5251 0.3571
Control time_m18 46.4913 0.3832
Control time_m24 43.8836 0.5016
Control time_m6 40.4271 0.3208
NR time_m12 45.2511 0.4604
NR time_m18 45.6108 0.5258
NR time_m24 44.3427 0.6986
NR time_m6 41.2183 0.4373


Pairwise comparisons (Tukey multiple-test correction)

comparison time estimate SE df t.ratio p.value
Control - NR time_m6 -0.7912 0.5941 1951 -1.3319 0.1831
Control - NR time_m12 0.274 0.6083 1951 0.4504 0.6525
Control - NR time_m18 0.8805 0.6486 1951 1.3575 0.1748
Control - NR time_m24 -0.4591 0.7599 1951 -0.6042 0.5458










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