ITP phenotypes:   grip strength     nordihydroguaiaretic acid

Trial code: NDGA_hi Dose: 5000 ppm   initiated at age: 6 mo Sex: f Cohort: C2010
Trial code: NDGA_mid Dose: 2500 ppm   initiated at age: 6 mo Sex: m Cohort: C2010
The plots below show the means with ± SEM error bars





ANOVA

Factor Df Sum Sq Mean Sq F value Pr(>F)
group 2 11504.4952 5752.2476 2.0947 0.1251
Residuals 267 733222.8567 2746.153 NA NA


Means

group mean SE
Old_Control 280.73 6.0201
Old_NDGA_hi 294.2 5.5809
Young_Control 294.3067 4.1655


Pairwise comparisons (Tukey multiple-test correction)

contrast estimate SE df t.ratio p.value
Old_Control - Old_NDGA_hi -13.47 7.5079 267 -1.7941 0.1735
Old_Control - Young_Control -13.5767 8.0048 267 -1.6961 0.2086
Old_NDGA_hi - Young_Control -0.1067 8.0946 267 -0.0132 0.9999










ANOVA

Factor Df Sum Sq Mean Sq F value Pr(>F)
group 2 66023.2584 33011.6292 12.0981 < 0.0001
Residuals 222 605765.3816 2728.6729 NA NA


Means

group mean SE
Old_Control 273.9429 4.6953
Old_NDGA_mid 291.3778 7.636
Young_Control 312.7733 6.7059


Pairwise comparisons (Tukey multiple-test correction)

contrast estimate SE df t.ratio p.value
Old_Control - Old_NDGA_mid -17.4349 9.3072 222 -1.8733 0.1489
Old_Control - Young_Control -38.8305 7.8974 222 -4.9168 < 0.0001
Old_NDGA_mid - Young_Control -21.3956 9.8498 222 -2.1722 0.0783










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