ITP phenotypes:   body weight     geranylgeranyl acetone

Trial code: GGA Dose: 600 ppm   initiated at age: 9 mo Sex: f Cohort: C2016
Trial code: GGA Dose: 600 ppm   initiated at age: 9 mo Sex: m Cohort: C2016
The plots below show the means with ± SEM error bars





ANOVA

Factor Df Sum Sq Mean Sq F value Pr(>F)
group 1 582.9726 582.9726 7.9654 0.0049
time 3 24441.6627 8147.2209 111.3193 < 0.0001
group:time 3 425.6851 141.895 1.9388 0.1215
Residuals 1126 82409.5431 73.1879 NA NA


Means

group time mean SE
Control time_m12 41.4571 0.5573
Control time_m18 45.6604 0.6419
Control time_m24 44.8555 0.7746
Control time_m6 33.1995 0.4124
GGA time_m12 39.769 1.0613
GGA time_m18 43.7679 1.1077
GGA time_m24 41.4425 0.9787
GGA time_m6 33.6114 0.6983


Pairwise comparisons (Tukey multiple-test correction)

comparison time estimate SE df t.ratio p.value
Control - GGA time_m6 -0.4118 1.0849 1126 -0.3796 0.7043
Control - GGA time_m12 1.6882 1.0908 1126 1.5477 0.122
Control - GGA time_m18 1.8925 1.1067 1126 1.71 0.0875
Control - GGA time_m24 3.413 1.194 1126 2.8585 0.0043










ANOVA

Factor Df Sum Sq Mean Sq F value Pr(>F)
group 1 71.3768 71.3768 1.4683 0.2258
time 3 11065.1918 3688.3973 75.8736 < 0.0001
group:time 3 251.3318 83.7773 1.7234 0.1601
Residuals 1942 94405.2456 48.6124 NA NA


Means

group time mean SE
Control time_m12 45.5251 0.3571
Control time_m18 46.4913 0.3832
Control time_m24 43.8836 0.5016
Control time_m6 40.4271 0.3208
GGA time_m12 44.8461 0.5156
GGA time_m18 46.7112 0.5663
GGA time_m24 42.1602 0.8258
GGA time_m6 40.6794 0.4269


Pairwise comparisons (Tukey multiple-test correction)

comparison time estimate SE df t.ratio p.value
Control - GGA time_m6 -0.2523 0.6161 1942 -0.4096 0.6822
Control - GGA time_m12 0.679 0.6392 1942 1.0624 0.2882
Control - GGA time_m18 -0.22 0.6787 1942 -0.3241 0.7459
Control - GGA time_m24 1.7235 0.7609 1942 2.2649 0.0236










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