ITP phenotypes:   postprandial glucose     acarbose

Trial code: ACA Dose: 400, 1000, 2500 ppm   initiated at age: 4 mo Sex: f Cohort: C2013
Trial code: ACA Dose: 400, 1000, 2500 ppm   initiated at age: 4 mo Sex: m Cohort: C2013
The plots below show the means with ± SEM error bars





ANOVA

Factor Df Sum Sq Mean Sq F value Pr(>F)
group 3 2180.655 726.885 2.9669 0.0334
time 4 9349.28 2337.32 9.5401 < 0.0001
group:time 12 2689.32 224.11 0.9147 0.5334
Residuals 180 44099.9 244.9994 NA NA


Means

group time mean SE
ACA_hi time_min0 110 3.6818
ACA_hi time_min180 110.2 4.1868
ACA_hi time_min30 123.2 5.7616
ACA_hi time_min360 122.1 4.2044
ACA_hi time_min60 129.1 5.3778
ACA_lo time_min0 110.3 3.9216
ACA_lo time_min180 115.9 4.1725
ACA_lo time_min30 122.7 7.3
ACA_lo time_min360 121.6 3.8012
ACA_lo time_min60 131.1 8.4898
ACA_mid time_min0 117.9 5.5306
ACA_mid time_min180 121.1 5.1304
ACA_mid time_min30 133 4.2005
ACA_mid time_min360 125.9 4.5667
ACA_mid time_min60 122.9 3.979
Control time_min0 117.2 4.0628
Control time_min180 118 3.7624
Control time_min30 139.5 3.3408
Control time_min360 121.6 6.0886
Control time_min60 140.4 4.0475


Pairwise comparisons (Tukey multiple-test correction)

contrast time estimate SE df t.ratio p.value
ACA_hi - ACA_lo time_min0 -0.3 7 180 -0.0429 1
ACA_hi - ACA_mid time_min0 -7.9 7 180 -1.1286 0.6724
ACA_hi - Control time_min0 -7.2 7 180 -1.0286 0.7329
ACA_lo - ACA_mid time_min0 -7.6 7 180 -1.0857 0.6987
ACA_lo - Control time_min0 -6.9 7 180 -0.9857 0.7578
ACA_mid - Control time_min0 0.7 7 180 0.1 0.9996
ACA_hi - ACA_lo time_min30 0.5 7 180 0.0714 0.9999
ACA_hi - ACA_mid time_min30 -9.8 7 180 -1.4 0.501
ACA_hi - Control time_min30 -16.3 7 180 -2.3286 0.0954
ACA_lo - ACA_mid time_min30 -10.3 7 180 -1.4714 0.4569
ACA_lo - Control time_min30 -16.8 7 180 -2.4 0.0807
ACA_mid - Control time_min30 -6.5 7 180 -0.9286 0.7896
ACA_hi - ACA_lo time_min60 -2 7 180 -0.2857 0.9918
ACA_hi - ACA_mid time_min60 6.2 7 180 0.8857 0.8123
ACA_hi - Control time_min60 -11.3 7 180 -1.6143 0.3732
ACA_lo - ACA_mid time_min60 8.2 7 180 1.1714 0.6456
ACA_lo - Control time_min60 -9.3 7 180 -1.3286 0.546
ACA_mid - Control time_min60 -17.5 7 180 -2.5 0.0633
ACA_hi - ACA_lo time_min180 -5.7 7 180 -0.8143 0.8477
ACA_hi - ACA_mid time_min180 -10.9 7 180 -1.5571 0.4058
ACA_hi - Control time_min180 -7.8 7 180 -1.1143 0.6812
ACA_lo - ACA_mid time_min180 -5.2 7 180 -0.7429 0.8796
ACA_lo - Control time_min180 -2.1 7 180 -0.3 0.9906
ACA_mid - Control time_min180 3.1 7 180 0.4429 0.9709
ACA_hi - ACA_lo time_min360 0.5 7 180 0.0714 0.9999
ACA_hi - ACA_mid time_min360 -3.8 7 180 -0.5429 0.9484
ACA_hi - Control time_min360 0.5 7 180 0.0714 0.9999
ACA_lo - ACA_mid time_min360 -4.3 7 180 -0.6143 0.9274
ACA_lo - Control time_min360 0 7 180 0 1
ACA_mid - Control time_min360 4.3 7 180 0.6143 0.9274










ANOVA

Factor Df Sum Sq Mean Sq F value Pr(>F)
group 3 22129.4 7376.4667 21.6655 < 0.0001
time 4 15907.87 3976.9675 11.6808 < 0.0001
group:time 12 4426.85 368.9042 1.0835 0.3765
Residuals 180 61284.6 340.47 NA NA


Means

group time mean SE
ACA_hi time_min0 101 2.1807
ACA_hi time_min180 103.8 2.6658
ACA_hi time_min30 122.9 6.0506
ACA_hi time_min360 111.3 3.1307
ACA_hi time_min60 118.8 4.3838
ACA_lo time_min0 113.1 4.972
ACA_lo time_min180 127.6 6.2684
ACA_lo time_min30 131.8 6.2978
ACA_lo time_min360 133 3.6515
ACA_lo time_min60 139.5 5.4676
ACA_mid time_min0 118.7 3.1939
ACA_mid time_min180 115.9 5.1065
ACA_mid time_min30 133.1 4.127
ACA_mid time_min360 135.4 9.3371
ACA_mid time_min60 136.8 3.7529
Control time_min0 122.3 6.8298
Control time_min180 140.5 7.5722
Control time_min30 153.8 7.6475
Control time_min360 131.1 7.3793
Control time_min60 158 9.222


Pairwise comparisons (Tukey multiple-test correction)

contrast time estimate SE df t.ratio p.value
ACA_hi - ACA_lo time_min0 -12.1 8.2519 180 -1.4663 0.46
ACA_hi - ACA_mid time_min0 -17.7 8.2519 180 -2.145 0.143
ACA_hi - Control time_min0 -21.3 8.2519 180 -2.5812 0.0516
ACA_lo - ACA_mid time_min0 -5.6 8.2519 180 -0.6786 0.9051
ACA_lo - Control time_min0 -9.2 8.2519 180 -1.1149 0.6808
ACA_mid - Control time_min0 -3.6 8.2519 180 -0.4363 0.9721
ACA_hi - ACA_lo time_min30 -8.9 8.2519 180 -1.0785 0.7031
ACA_hi - ACA_mid time_min30 -10.2 8.2519 180 -1.2361 0.6048
ACA_hi - Control time_min30 -30.9 8.2519 180 -3.7446 0.0014
ACA_lo - ACA_mid time_min30 -1.3 8.2519 180 -0.1575 0.9986
ACA_lo - Control time_min30 -22 8.2519 180 -2.666 0.0413
ACA_mid - Control time_min30 -20.7 8.2519 180 -2.5085 0.062
ACA_hi - ACA_lo time_min60 -20.7 8.2519 180 -2.5085 0.062
ACA_hi - ACA_mid time_min60 -18 8.2519 180 -2.1813 0.1324
ACA_hi - Control time_min60 -39.2 8.2519 180 -4.7504 < 0.0001
ACA_lo - ACA_mid time_min60 2.7 8.2519 180 0.3272 0.9879
ACA_lo - Control time_min60 -18.5 8.2519 180 -2.2419 0.116
ACA_mid - Control time_min60 -21.2 8.2519 180 -2.5691 0.0532
ACA_hi - ACA_lo time_min180 -23.8 8.2519 180 -2.8842 0.0226
ACA_hi - ACA_mid time_min180 -12.1 8.2519 180 -1.4663 0.46
ACA_hi - Control time_min180 -36.7 8.2519 180 -4.4475 0.0001
ACA_lo - ACA_mid time_min180 11.7 8.2519 180 1.4179 0.4899
ACA_lo - Control time_min180 -12.9 8.2519 180 -1.5633 0.4023
ACA_mid - Control time_min180 -24.6 8.2519 180 -2.9811 0.0171
ACA_hi - ACA_lo time_min360 -21.7 8.2519 180 -2.6297 0.0455
ACA_hi - ACA_mid time_min360 -24.1 8.2519 180 -2.9205 0.0204
ACA_hi - Control time_min360 -19.8 8.2519 180 -2.3994 0.0808
ACA_lo - ACA_mid time_min360 -2.4 8.2519 180 -0.2908 0.9914
ACA_lo - Control time_min360 1.9 8.2519 180 0.2302 0.9957
ACA_mid - Control time_min360 4.3 8.2519 180 0.5211 0.9539










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