ITP phenotypes: uterus weight, OVX 17-a-estradiol
Trial code: 17aE2_hi
Dose: 14 ppm
initiated at age: 10 mo
Sex: f
Cohort: C2011
Trial code: 17aE2_lo
Dose: 4.8 ppm
initiated at age: 10 mo
Sex: f
Cohort: C2011
The plots below show the means with ± SEM error bars
Analysis details -- Female
ANOVA
Factor Df Sum Sq Mean Sq F value Pr(>F)
group 2 18740.0286 9370.0143 19.6985 0.0001
Residuals 15 7135.0875 475.6725 NA NA
Means
group mean SE
17aE2_hi 93.2 12.4608
17aE2_lo 33.2 3.3564
OVX_Control 18.775 3.4226
Pairwise comparisons (Tukey multiple-test correction)
contrast estimate SE df t.ratio p.value
17aE2_hi - 17aE2_lo 60 11.6579 15 5.1467 0.0003
17aE2_hi - OVX_Control 74.425 13.6701 15 5.4444 0.0002
17aE2_lo - OVX_Control 14.425 13.6701 15 1.0552 0.5551
Analysis details -- Female
ANOVA
Factor Df Sum Sq Mean Sq F value Pr(>F)
group 1 35402.9406 35402.9406 30.7052 0.0001
Residuals 12 13835.9365 1152.9947 NA NA
Means
group mean SE
Intact_Control 130.09 12.3358
OVX_Control 18.775 3.4226
Pairwise comparisons (Tukey multiple-test correction)
contrast estimate SE df t.ratio p.value
Intact_Control - OVX_Control 111.315 20.0885 12 5.5412 0.0001
See our
ITP data portal page for more information on
National Institute on Aging's Interventions Testing Program (ITP) including bibliography, data set downloads, and links to all available hosted data.