ITP phenotypes:   uterus weight, OVX     17-a-estradiol

Trial code: 17aE2_hi Dose: 14 ppm   initiated at age: 10 mo Sex: f Cohort: C2011
Trial code: 17aE2_lo Dose: 4.8 ppm   initiated at age: 10 mo Sex: f Cohort: C2011
The plots below show the means with ± SEM error bars





ANOVA

Factor Df Sum Sq Mean Sq F value Pr(>F)
group 2 18740.0286 9370.0143 19.6985 0.0001
Residuals 15 7135.0875 475.6725 NA NA


Means

group mean SE
17aE2_hi 93.2 12.4608
17aE2_lo 33.2 3.3564
OVX_Control 18.775 3.4226


Pairwise comparisons (Tukey multiple-test correction)

contrast estimate SE df t.ratio p.value
17aE2_hi - 17aE2_lo 60 11.6579 15 5.1467 0.0003
17aE2_hi - OVX_Control 74.425 13.6701 15 5.4444 0.0002
17aE2_lo - OVX_Control 14.425 13.6701 15 1.0552 0.5551










ANOVA

Factor Df Sum Sq Mean Sq F value Pr(>F)
group 1 35402.9406 35402.9406 30.7052 0.0001
Residuals 12 13835.9365 1152.9947 NA NA


Means

group mean SE
Intact_Control 130.09 12.3358
OVX_Control 18.775 3.4226


Pairwise comparisons (Tukey multiple-test correction)

contrast estimate SE df t.ratio p.value
Intact_Control - OVX_Control 111.315 20.0885 12 5.5412 0.0001










See our ITP data portal page for more information on National Institute on Aging's Interventions Testing Program (ITP) including bibliography, data set downloads, and links to all available hosted data.