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Project data set: Jaxwest1   (2003)

Project Multi-system analysis of physiology on 7 inbred strains of mice

Animals were assessed in these areas: body and bone composition, cardiovascular, grip strength, pain sensitivity using DXA system, conscious non-invasive ECG and blood pressure, cold/hot plate analgesia, and grip strength.

Study design: baseline survey; 1 cohort.
7 strains tested     female male     Test age: 8-14wks

Investigators Jackson Laboratory   [Details]
The Jackson Laboratory In Vivo Services

Protocol View phenotyping protocol and methods

Jaxwest1
measurements



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For downloads and additional info see bottom of page...  


body composition         DXA  
Jaxwest1
percent fat, head excluded   [%]
7 strains   age 11-13wks
  Inbred
Jaxwest1
fat weight, head excluded   [g]
7 strains   age 11-13wks
  Inbred
Jaxwest1
lean weight, head excluded   [g]
7 strains   age 11-13wks
  Inbred
Jaxwest1
total tissue mass, head excluded   [g]
7 strains   age 11-13wks
  Inbred
 
body weight         scales  
Jaxwest1
body weight   [g]
7 strains   age 11-13wks
  Inbred
 
bone — mineral density and content — femur         DXA  
Jaxwest1
femur bone mineral density and content  
      • BMD  • BMC 
7 strains   age 11-13wks
  Inbred
 
bone — mineral density and content — spine         DXA  
Jaxwest1
spine bone mineral density and content  
      • BMD  • BMC 
7 strains   age 11-13wks
  Inbred
 
bone — mineral density and content — whole body without head         DXA  
Jaxwest1
bone mineral density and content  
      • BMD  • BMC 
7 strains   age 11-13wks
  Inbred
 
cardiovascular — blood pressure         tail cuff  
Jaxwest1
systolic blood pressure   [mmHg]
7 strains   age 9-14wks
  Inbred
 
cardiovascular — ECG parameters — conscious         ECG  
Jaxwest1
intervals [ms]  
      • RR   • PQ   • PR   • QRS   • QT   • QTc   • ST 
7 strains   age 8-10wks
  Inbred
 
cardiovascular — heart rate — conscious         ECG  
Jaxwest1
heart rate [n/min]  
      • heart rate  • variability  • CV 
7 strains   age 8-10wks
  Inbred
 
cardiovascular — heart rate — conscious         tail cuff  
Jaxwest1
pulse rate   [n/min]
7 strains   age 9-14wks
  Inbred
 
muscle — skeletal — function         grip strength  
Jaxwest1
grip strength, peak tension over 5 trials [g]  
      • mean   • maximum 
7 strains   age 9-12wks
  Inbred
 
neurosensory — nociception — thermal         nociception assay  
Jaxwest1
sensitivity to thermal-induced pain using hotplate  
      • latency to respond    • hindpaw response 
7 strains   age 9-12wks
  Inbred



Number of mice tested per strain, for each measurement

  
Changelog There have been 3 updates or corrections to the data set since MPD release in Jun 2004  
Mice
Strain and animal info

Jaxwest1
downloads


Individual animal data
Table format (.csv)
Individual animal data in table format, with one row per animal and one column per measurement.
Individual animal data
List format (.csv)
Individual animal data organized as one row per animal / measurement reading.
Strain means (.csv) Strain means with SD, N, other summary statistics. One row per strain / sex / measurement.
Supplemental data are available

 See also the MPD download center for more general data download options.





 




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