Project measure / variable:   Jaxwest1   QTc

ID, description, units MPD:15106   QTc   rate-corrected QT interval   [ms]  
Data set, strains Jaxwest1   inbred   7 strains     sex: both     age: 8-10wks
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  STRAIN COMPARISON PLOT
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Jaxwest1 - rate-corrected QT interval



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested7 strains7 strains
Mean of the strain means51.9   ms 50.5   ms
Median of the strain means52.6   ms 51.6   ms
SD of the strain means± 2.43 ± 4.10
Coefficient of variation (CV)0.0469 0.0813
Min–max range of strain means47.4   –   54.8   ms 41.7   –   53.8   ms
Mean sample size per strain7.9   mice 7.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 30.0525 30.0525 1.9715 0.1636
strain 6 786.7834 131.1306 8.6025 < 0.0001
sex:strain 6 140.6241 23.4374 1.5375 0.1746
Residuals 93 1417.6359 15.2434


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 54.8 4.92   8 1.74 0.0899 44.2, 60.1 1.19
129S1/SvImJ m 53.8 4.04   8 1.43 0.0752 47.0, 60.9 0.8
A/J f 52.3 2.86   8 1.01 0.0548 48.6, 56.7 0.16
A/J m 53.2 3.01   8 1.06 0.0564 49.1, 56.9 0.66
BALB/cJ f 52.9 1.31   7 0.496 0.0248 50.6, 54.1 0.41
BALB/cJ m 52.0 4.06   8 1.44 0.0782 44.5, 58.6 0.37
C57BL/6J f 52.6 3.36   8 1.19 0.0638 47.0, 56.3 0.28
C57BL/6J m 51.6 6.41   7 2.42 0.124 38.8, 56.5 0.27
DBA/2J f 53.3 4.32   8 1.53 0.0811 46.0, 59.2 0.57
DBA/2J m 49.6 3.77   7 1.42 0.0759 45.0, 56.6 -0.22
NOD/ShiLtJ f 50.1 4.26   8 1.51 0.0851 40.3, 53.6 -0.75
NOD/ShiLtJ m 51.6 3.03   8 1.07 0.0588 45.3, 54.8 0.27
SJL/J f 47.4 4.43   8 1.57 0.0934 40.6, 52.9 -1.86
SJL/J m 41.7 1.87   6 0.763 0.0448 40.1, 44.2 -2.14


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 54.7625 1.3804 57.5036 52.0214
129S1/SvImJ m 53.7625 1.3804 56.5036 51.0214
A/J f 52.275 1.3804 55.0161 49.5339
A/J m 53.2375 1.3804 55.9786 50.4964
BALB/cJ f 52.9143 1.4757 55.8447 49.9839
BALB/cJ m 51.9625 1.3804 54.7036 49.2214
C57BL/6J f 52.65 1.3804 55.3911 49.9089
C57BL/6J m 51.6143 1.4757 54.5447 48.6839
DBA/2J f 53.275 1.3804 56.0161 50.5339
DBA/2J m 49.6 1.4757 52.5304 46.6696
NOD/ShiLtJ f 50.0625 1.3804 52.8036 47.3214
NOD/ShiLtJ m 51.575 1.3804 54.3161 48.8339
SJL/J f 47.4 1.3804 50.1411 44.6589
SJL/J m 41.7 1.5939 44.8652 38.5348


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 54.2625 0.9761 56.2008 52.3242
A/J both 52.7562 0.9761 54.6945 50.818
BALB/cJ both 52.4384 1.0103 54.4447 50.4321
C57BL/6J both 52.1321 1.0103 54.1385 50.1258
DBA/2J both 51.4375 1.0103 53.4438 49.4312
NOD/ShiLtJ both 50.8187 0.9761 52.757 48.8805
SJL/J both 44.55 1.0543 46.6436 42.4564




  GWAS USING LINEAR MIXED MODELS