Project measure / variable:   Jaxwest1   HR_var

ID, description, units MPD:15109   HR_var   heart rate variability   [n/min]  
Data set, strains Jaxwest1   inbred   7 strains     sex: both     age: 8-10wks
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  STRAIN COMPARISON PLOT
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Jaxwest1 - heart rate variability



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested7 strains7 strains
Mean of the strain means59.5   n/min 51.8   n/min
Median of the strain means46.9   n/min 45.1   n/min
SD of the strain means± 35.7 ± 32.8
Coefficient of variation (CV)0.600 0.633
Min–max range of strain means6.48   –   108   n/min 14.0   –   106   n/min
Mean sample size per strain7.9   mice 7.6   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 1220.7136 1220.7136 0.6005 0.4404
strain 6 60927.7897 10154.6316 4.9949 0.0002
sex:strain 6 49205.2988 8200.8831 4.0339 0.0012
Residuals 94 191101.2411 2032.9919


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 108.0 27.0   8 9.56 0.251 70.3, 149.0 1.36
129S1/SvImJ m 106.0 68.3   8 24.1 0.647 5.0, 189.0 1.65
A/J f 46.3 29.0   8 10.3 0.626 16.2, 85.1 -0.37
A/J m 45.1 31.7   8 11.2 0.702 9.7, 96.6 -0.21
BALB/cJ f 46.9 39.7   7 15.0 0.846 18.8, 123.0 -0.35
BALB/cJ m 36.1 30.8   8 10.9 0.855 8.8, 90.1 -0.48
C57BL/6J f 101.0 56.5   8 20.0 0.558 18.5, 172.0 1.16
C57BL/6J m 27.3 24.0   7 9.08 0.88 4.0, 71.5 -0.75
DBA/2J f 67.3 52.1   8 18.4 0.774 7.8, 130.0 0.22
DBA/2J m 48.0 67.9   7 25.7 1.41 3.8, 191.0 -0.12
NOD/ShiLtJ f 6.48 2.76   8 0.975 0.426 4.4, 13.0 -1.49
NOD/ShiLtJ m 86.4 78.4   8 27.7 0.907 10.3, 211.0 1.05
SJL/J f 40.5 32.5   8 11.5 0.801 9.3, 100.0 -0.53
SJL/J m 14.0 15.7   7 5.94 1.12 5.0, 49.0 -1.15


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 107.775 15.9413 139.4268 76.1232
129S1/SvImJ m 105.5 15.9413 137.1518 73.8482
A/J f 46.35 15.9413 78.0018 14.6982
A/J m 45.075 15.9413 76.7268 13.4232
BALB/cJ f 46.9 17.0419 80.7372 13.0628
BALB/cJ m 36.0625 15.9413 67.7143 4.4107
C57BL/6J f 101.225 15.9413 132.8768 69.5732
C57BL/6J m 27.3 17.0419 61.1372 0.0
DBA/2J f 67.275 15.9413 98.9268 35.6232
DBA/2J m 48.0143 17.0419 81.8514 14.1771
NOD/ShiLtJ f 6.475 15.9413 38.1268 0.0
NOD/ShiLtJ m 86.4 15.9413 118.0518 54.7482
SJL/J f 40.5375 15.9413 72.1893 8.8857
SJL/J m 14.0 17.0419 47.8372 0.0


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 106.6375 11.2722 129.0187 84.2563
A/J both 45.7125 11.2722 68.0937 23.3313
BALB/cJ both 41.4813 11.6678 64.648 18.3145
C57BL/6J both 64.2625 11.6678 87.4292 41.0958
DBA/2J both 57.6446 11.6678 80.8114 34.4779
NOD/ShiLtJ both 46.4375 11.2722 68.8187 24.0563
SJL/J both 27.2687 11.6678 50.4355 4.102




  GWAS USING LINEAR MIXED MODELS