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C57BL/6J
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Data set
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Rusyn6
(25)
Procedure / Protocol
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drug and metaboli...
(13)
histopathology
(3)
metabolic panel
(1)
organ weights
(2)
RNA expression pr...
(6)
Treatment
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trichloroethylene
(25)
Panel
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inbred
(25)
Sex
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m
(25)
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Procedure / Protocol
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Panel
No. of Strains
Sex
Age
Sample Size (Avg)
Year
Rusyn6:2
Rusyn6
drug and metabolite quantification
trichloroethylene
trichloroacetic acid (serum TCA) [nmol/mL]
TCA_serum_tce
51202
inbred
7
m
6-7wks
N=3
2014
Rusyn6:4
Rusyn6
drug and metabolite quantification
trichloroethylene
dichloroacetic acid (serum DCA) [nmol/mL]
DCA_serum_tce
51204
inbred
7
m
6-7wks
N=3
2014
Rusyn6:6
Rusyn6
drug and metabolite quantification
trichloroethylene
S-(1,2-dichlorovinyl) glutathione (serum DCVG) [pmol/mL]
DCVG_serum_tce
51206
inbred
4
m
6-7wks
N=2
2014
Rusyn6:8
Rusyn6
drug and metabolite quantification
trichloroethylene
S-(1,2-dichlorovinyl)-L-cysteine (serum DCVC) [pmol/mL]
DCVC_serum_tce
51208
inbred
7
m
6-7wks
N=3
2014
Rusyn6:9
Rusyn6
metabolic panel
trichloroethylene
blood urea nitrogen (serum BUN) [mg/dL]
BUN
51209
control TCE
inbred
7
m
6-7wks
N=4
2014
Rusyn6:11
Rusyn6
organ weights
trichloroethylene
liver weight as a percent of body weight [%]
liver_adj
51211
control TCE
inbred
7
m
6-7wks
N=4
2014
Rusyn6:14
Rusyn6
histopathology
trichloroethylene
BrdU-positive nuclei in liver (hepatocellular proliferation), relative to control group [%]
BrdU_liver_tce
51214
inbred
7
m
6-7wks
N=3
2014
Rusyn6:16
Rusyn6
drug and metabolite quantification
trichloroethylene
trichloroacetic acid (liver TCA) [nmol/g]
TCA_liver_tce
51216
inbred
7
m
6-7wks
N=4
2014
Rusyn6:18
Rusyn6
drug and metabolite quantification
trichloroethylene
dichloroacetic acid (liver DCA) [nmol/g]
DCA_liver_tce
51218
inbred
7
m
6-7wks
N=4
2014
Rusyn6:20
Rusyn6
drug and metabolite quantification
trichloroethylene
trichloroethanol (liver TCOH) [nmol/g]
TCOH_liver_tce
51220
inbred
7
m
6-7wks
N=4
2014
Rusyn6:22
Rusyn6
drug and metabolite quantification
trichloroethylene
S-(1,2-dichlorovinyl) glutathione (liver DCVG) [pmol/g]
DCVG_liver_tce
51222
inbred
7
m
6-7wks
N=4
2014
Rusyn6:26
Rusyn6
RNA expression profiling
trichloroethylene
Acox1, mRNA in liver, relative to control group [ratio]
Acox1_liver_tce
51226
inbred
7
m
6-7wks
N=3
2014
Rusyn6:28
Rusyn6
RNA expression profiling
trichloroethylene
Cyp4a10, mRNA in liver, relative to control group [ratio]
Cyp4a10_liver_tce
51228
inbred
7
m
6-7wks
N=3
2014
Rusyn6:30
Rusyn6
RNA expression profiling
trichloroethylene
Ppara, mRNA in liver, relative to control group [ratio]
Ppara_liver_tce
51230
inbred
7
m
6-7wks
N=3
2014
Rusyn6:51
Rusyn6
organ weights
trichloroethylene
kidney weight as a percent of body weight [%]
kidney_adj
51251
control TCE
inbred
7
m
6-7wks
N=4
2014
Rusyn6:54
Rusyn6
histopathology
trichloroethylene
BrdU-positive nuclei in kidney (proximal tubule cell proliferation), relative to control group [%]
BrdU_kidney_tce
51254
inbred
7
m
6-7wks
N=3
2014
Rusyn6:55
Rusyn6
histopathology
trichloroethylene
kidney injury molecule 1 (KIM-1) positive proximal tubules [%]
KIM1_kidney
51255
control TCE
inbred
7
m
6-7wks
N=4
2014
Rusyn6:58
Rusyn6
drug and metabolite quantification
trichloroethylene
trichloroacetic acid (kidney TCA) [nmol/g]
TCA_kidney_tce
51258
inbred
7
m
6-7wks
N=4
2014
Rusyn6:60
Rusyn6
drug and metabolite quantification
trichloroethylene
dichloroacetic acid (kidney DCA) [nmol/g]
DCA_kidney_tce
51260
inbred
6
m
6-7wks
N=3
2014
Rusyn6:62
Rusyn6
drug and metabolite quantification
trichloroethylene
trichloroethanol (kidney TCOH) [nmol/g]
TCOH_kidney_tce
51262
inbred
7
m
6-7wks
N=4
2014
Rusyn6:64
Rusyn6
drug and metabolite quantification
trichloroethylene
S-(1,2-dichlorovinyl) glutathione (kidney DCVG) [pmol/g]
DCVG_kidney_tce
51264
inbred
6
m
6-7wks
N=2
2014
Rusyn6:66
Rusyn6
drug and metabolite quantification
trichloroethylene
S-(1,2-dichlorovinyl)-L-cysteine (kidney DCVC) [pmol/g]
DCVC_kidney_tce
51266
inbred
6
m
6-7wks
N=2
2014
Rusyn6:68
Rusyn6
RNA expression profiling
trichloroethylene
Acox1, mRNA in kidney, relative to control group [ratio]
Acox1_kidney_tce
51268
inbred
7
m
6-7wks
N=3
2014
Rusyn6:70
Rusyn6
RNA expression profiling
trichloroethylene
Cyp4a10, mRNA in kidney, relative to control group [ratio]
Cyp4a10_kidney_tce
51270
inbred
7
m
6-7wks
N=3
2014
Rusyn6:72
Rusyn6
RNA expression profiling
trichloroethylene
Ppara, mRNA in kidney, relative to control group [ratio]
Ppara_kidney_tce
51272
inbred
7
m
6-7wks
N=3
2014
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