MPD: Project measures / variables set: Rusyn6 KIM1

Project measures / variables set: Rusyn6 KIM1_kidney

ID, description, units	MPD:51255 KIM1_kidney kidney injury molecule 1 (KIM-1) positive proximal tubules [%] trichloroethylene study
Measures	• control • TCE
Data set, strains	Rusyn6 inbred 7 strains sex: m age: 6-7wks
Procedure	histopathology
Comparison	control group vs. treated group
Ontology mappings	VT:0010120 protein amount VT:0010487 response to xenobiotic stimulus trait MA:0000368 kidney MP:0008469 abnormal protein level MP:0008872 abnormal physiological response to xenobiotic

Values Means Δ Means Z-scores

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Rusyn6 - kidney injury molecule 1 (KIM-1) positive proximal tubules

ANOVA Summary

Factor	DF	Sum of squares	Mean sum of squares	F value	p-value (Pr>F)
group	1	1153.0014	1153.0014	9.9333	0.0031
group:strain	6	793.8679	132.3113	1.1399	0.3579
Residuals	39	4526.8825	116.0739
strain	6	2022.9169	337.1528	2.9046	0.0194

Q-Q normality assessment based on residuals

INDIVIDUAL MEASURES

Project	ID		Treatment	Measure / Variable Description	Panel	Strains tested	Sex	Age
Rusyn6	51255	histopathology	trichloroethylene	kidney injury molecule 1 (KIM-1) positive proximal tubules [%] control KIM1_kidney_ctrl	inbred	7	m	6-7wks
Rusyn6	51256	histopathology	trichloroethylene	kidney injury molecule 1 (KIM-1) positive proximal tubules [%] TCE KIM1_kidney_tce	inbred	7	m	6-7wks