Project measure / variable:   Rusyn6   TCOH_kidney_tce

ID, description, units MPD:51262   TCOH_kidney_tce   trichloroethanol (kidney TCOH)   [nmol/g]  
trichloroethylene study
Data set, strains Rusyn6   inbred   7 strains     sex: m     age: 6-7wks
Procedure drug and metabolite quantification
Ontology mappings

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  STRAIN COMPARISON PLOT
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Rusyn6 - trichloroethanol (kidney TCOH)



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested7 strains
Mean of the strain means2245   nmol/g
Median of the strain means2050   nmol/g
SD of the strain means± 938
Coefficient of variation (CV)0.418
Min–max range of strain means1162   –   3886   nmol/g
Mean sample size per strain3.6   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 6 16929380.5636 2821563.4273 5.6237 0.0019
Residuals 18 9031055.9908 501725.3328


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ m 3886.0 1288.0   3 744.0 0.332 2625.0, 5200.0 1.75
A/J m 2574.0 775.0   4 387.0 0.301 1834.0, 3324.0 0.35
BTBR T+ Itpr3tf/J m 1689.0 321.0   3 186.0 0.19 1421.0, 2045.0 -0.59
C57BL/6J m 1490.0 560.0   4 280.0 0.376 790.0, 2010.0 -0.81
CAST/EiJ m 1162.0 412.0   3 238.0 0.355 847.0, 1628.0 -1.16
NOD/ShiLtJ m 2050.0 714.0   4 357.0 0.348 1494.0, 2993.0 -0.21
NZW/LacJ m 2865.0 546.0   4 273.0 0.19 2192.0, 3461.0 0.66


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ m 3886.2333 408.952 4745.4097 3027.057
A/J m 2573.6 354.1629 3317.6686 1829.5314
BTBR T+ Itpr3tf/J m 1688.7667 408.952 2547.943 829.5903
C57BL/6J m 1490.5 354.1629 2234.5686 746.4314
CAST/EiJ m 1161.6 408.952 2020.7764 302.4236
NOD/ShiLtJ m 2050.05 354.1629 2794.1186 1305.9814
NZW/LacJ m 2865.075 354.1629 3609.1436 2121.0064




  GWAS USING LINEAR MIXED MODELS