Project measure / variable:   Rusyn6   DCVC_serum_tce

ID, description, units MPD:51208   DCVC_serum_tce   S-(1,2-dichlorovinyl)-L-cysteine (serum DCVC)   [pmol/mL]  
trichloroethylene study
Data set, strains Rusyn6   inbred   7 strains     sex: m     age: 6-7wks
Procedure drug and metabolite quantification
Ontology mappings

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  STRAIN COMPARISON PLOT
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Rusyn6 - S-(1,2-dichlorovinyl)-L-cysteine (serum DCVC)



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested7 strains
Mean of the strain means2.81   pmol/mL
Median of the strain means2.95   pmol/mL
SD of the strain means± 0.734
Coefficient of variation (CV)0.261
Min–max range of strain means1.80   –   3.73   pmol/mL
Mean sample size per strain2.9   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 5 6.7785 1.3557 0.6636 0.6575
Residuals 13 26.5583 2.0429


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ m 3.5 1.01   4 0.505 0.289 2.9, 5.0 0.94
A/J m 2.95 0.495   2   0.35 0.168 2.6, 3.3 0.19
BTBR T+ Itpr3tf/J m 2.4 0.455   4 0.227 0.189 2.0, 3.0 -0.55
C57BL/6J m 3.73 2.97   3 1.71 0.795 1.5, 7.1 1.26
CAST/EiJ m 1.8 0.0   1   0.0 0.0 1.8, 1.8 -1.37
NOD/ShiLtJ m 3.2 1.08   3 0.624 0.338 2.0, 4.1 0.54
NZW/LacJ m 2.07 1.16   3 0.669 0.561 1.3, 3.4 -1.0


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ m 3.5 0.7147 5.0439 1.9561
A/J m 2.95 1.0107 5.1334 0.7666
BTBR T+ Itpr3tf/J m 2.4 0.7147 3.9439 0.8561
C57BL/6J m 3.7333 0.8252 5.5161 1.9506
NOD/ShiLtJ m 3.2 0.8252 4.9828 1.4172
NZW/LacJ m 2.0667 0.8252 3.8494 0.2839




  GWAS USING LINEAR MIXED MODELS