Odet1: Male reproduction in 8 inbred founder strains of the Collaborative Cross: Organ weights, testis histology and sperm count, morphology and metabolism (2015)

Odet F, Pan W, Bell TA, Goodson SG, Stevans AM, Yun Z, Aylor DL, Kao CY, McMillan L, de Villena FP, O'Brien DA. The Founder Strains of the Collaborative Cross Express a Complex Combination of Advantageous and Deleterious Traits for Male Reproduction. G3 (Bethesda). 2015 Oct 19;5(12):2671-83. doi: 10.1534/g3.115.020172.   PubMed 26483008  


       
Odet1 downloads
• Download Odet1 project data set     one row per animal, one column per trait
• Download Odet1 strain means, SD, N, etc.     one row per strain/sex/measure
Participants Deborah A O'Brien       University of North Carolina Chapel Hill, NC
Fanny Odet       University of North Carolina Chapel Hill, NC
Wenqi Pan       University of North Carolina Chapel Hill, NC
Fernando Pardo-Manuel de Villena       University of North Carolina Chapel Hill, NC
With: Bell TA, Goodson SG, Stevans AM, Yun Z, Aylor DL, Kao C-Y, McMillan L
ContactDeborah A O'Brien     dao@med.unc.edu     Lab web site
Part of a series: • Morphology, histology, metabolism   (this project) Odet1
• Sperm motility   see Odet2
Project type Phenotype strain survey data set
MPD identifiersOdet1     MPD:537
Data changelog No updates/corrections.       Initial release date: 04/2016.
Formatted citation
Click above to copy-paste the entire citation for this MPD web page.
Summary of procedures that were conducted
• body weight
• organ weights Male reproductive organ weights. Testes, seminal vesicles, epididymis, vas deferens.
• histopathology Male reproductive histopathology. Percent normal vs. abnormal sperm, seminiferous tubules.
• sperm count Sperm count. Hemocytometer.
• metabolic panel Male reproductive sperm lactate production.
Mice: inbred   8 strains   ♂   age 10-66wks   1 cohort

Select table page: First Prev Next Last
Data set MPD ID Procedure / Protocol Drug or Challenge Phenotype Measure Panel No. of Strains Sex Age Sample Size (Avg)
    Odet1 53701 body weight (none) body_weight   [g]  bw inbred w/CC8 8 m 10-66wks N=29
    Odet1 53711 organ weights (none) mean epididymis plus vas deferens weight   [g]  epidid_vasdef_wt inbred w/CC8 8 m 10-66wks N=21
    Odet1 53712 organ weights (none) seminal vesicles weight   [g]  seminal_ves_wt inbred w/CC8 8 m 10-66wks N=27
    Odet1 53713 organ weights (none) mean testis weight   [g]  testis_wt inbred w/CC8 8 m 10-66wks N=27
    Odet1 53721 histopathology (none) mean seminiferous tubule radius (transverse section)   [µm]  seminif_radius inbred w/CC8 8 m 10-66wks N=26
    Odet1 53722 histopathology (none) seminiferious epithelium length (transverse section)   [cm]  seminif_length inbred w/CC8 8 m 10-66wks N=26
    Odet1 53723 histopathology (none) number of seminiferous tubules (transverse section)   [n]  seminif_count inbred w/CC8 8 m 10-66wks N=26
    Odet1 53724 histopathology (none) number of seminiferous tubules with vacuoles (transverse section)   [n]  seminif_vacuoles inbred w/CC8 8 m 10-66wks N=26
    Odet1 53725 histopathology (none) number of seminiferous tubules with many vacuoles (transverse section)   [n]  seminif_many_vacuoles inbred w/CC8 8 m 10-66wks N=26
    Odet1 53726 histopathology (none) number of seminiferous tubules with germ cell loss (transverse section)   [n]  seminif_germ_loss inbred w/CC8 8 m 10-66wks N=18
    Odet1 53727 histopathology (none) number of seminiferous tubules with abnormal germ cells (transverse section)   [n]  seminif_germ_abnormal inbred w/CC8 8 m 10-66wks N=26
    Odet1 53728 histopathology (none) number of seminiferous tubules with germ cell sloughing (transverse section)   [n]  seminif_germ_slough inbred w/CC8 8 m 10-66wks N=26
    Odet1 53731 sperm count (none) sperm count per mouse (x 106)   [n]  sperm_per_mouse inbred w/CC8 8 m 10-66wks N=21
    Odet1 53732 sperm count (none) sperm count per mg testis weight (x 103)   [n]  sperm_per_testis inbred w/CC8 8 m 10-66wks N=20
    Odet1 53733 sperm count (none) sperm count per seminiferous epithelium length (x 103)   [n]  sperm_per_seminif inbred w/CC8 8 m 10-66wks N=19
    Odet1 53741 histopathology (none) percentage of sperm with normal morphology   [%]  sperm_normal inbred w/CC8 8 m 10-66wks N=14
    Odet1 53742 histopathology (none) percentage of sperm with abnormal head shape   [%]  sperm_abnormal_head inbred w/CC8 8 m 10-66wks N=14
    Odet1 53743 histopathology (none) percentage of sperm with abnormal tail bending   [%]  sperm_abnormal_tail inbred w/CC8 8 m 10-66wks N=14
    Odet1 53744 histopathology (none) percentage of sperm with broken tails   [%]  sperm_broken_tail inbred w/CC8 8 m 10-66wks N=14
    Odet1 53751 metabolic panel (none) lactate production per 108 sperm   [µmole]  sperm_lactate inbred w/CC8 8 m 10-66wks N=8
    All boxes             To see more rows use the paging control at top.