MPD: Phenotype measures mapped to MA:0000368, kidney

Sort/ Pick	Data set	Procedure / Protocol	Treatment	Phenotype Measure / Variable (click to view)	Panel	No. of Strains	Sex	Age	Sample Size (Avg)	Year
Rusyn6:51	Rusyn6	organ weights	trichloroethylene	kidney weight as a percent of body weight [%] kidney_adj 51251 control TCE	inbred	7	m	6-7wks	N=4	2014

Rusyn6:54	Rusyn6	histopathology	trichloroethylene	BrdU-positive nuclei in kidney (proximal tubule cell proliferation), relative to control group [%] BrdU_kidney_tce 51254	inbred	7	m	6-7wks	N=3	2014

Rusyn6:55	Rusyn6	histopathology	trichloroethylene	kidney injury molecule 1 (KIM-1) positive proximal tubules [%] KIM1_kidney 51255 control TCE	inbred	7	m	6-7wks	N=4	2014

Rusyn6:58	Rusyn6	drug and metabolite quantification	trichloroethylene	trichloroacetic acid (kidney TCA) [nmol/g] TCA_kidney_tce 51258	inbred	7	m	6-7wks	N=4	2014

Rusyn6:60	Rusyn6	drug and metabolite quantification	trichloroethylene	dichloroacetic acid (kidney DCA) [nmol/g] DCA_kidney_tce 51260	inbred	6	m	6-7wks	N=3	2014

Rusyn6:62	Rusyn6	drug and metabolite quantification	trichloroethylene	trichloroethanol (kidney TCOH) [nmol/g] TCOH_kidney_tce 51262	inbred	7	m	6-7wks	N=4	2014

Rusyn6:64	Rusyn6	drug and metabolite quantification	trichloroethylene	S-(1,2-dichlorovinyl) glutathione (kidney DCVG) [pmol/g] DCVG_kidney_tce 51264	inbred	6	m	6-7wks	N=2	2014

Rusyn6:66	Rusyn6	drug and metabolite quantification	trichloroethylene	S-(1,2-dichlorovinyl)-L-cysteine (kidney DCVC) [pmol/g] DCVC_kidney_tce 51266	inbred	6	m	6-7wks	N=2	2014

Rusyn6:68	Rusyn6	RNA expression profiling	trichloroethylene	Acox1, mRNA in kidney, relative to control group [ratio] Acox1_kidney_tce 51268	inbred	7	m	6-7wks	N=3	2014

Rusyn6:70	Rusyn6	RNA expression profiling	trichloroethylene	Cyp4a10, mRNA in kidney, relative to control group [ratio] Cyp4a10_kidney_tce 51270	inbred	7	m	6-7wks	N=3	2014

Rusyn6

organ weights

trichloroethylene

kidney weight as a percent of body weight [%] kidney_adj 51251 control TCE

inbred

7

m

6-7wks

N=4

2014

Rusyn6

histopathology

trichloroethylene

BrdU-positive nuclei in kidney (proximal tubule cell proliferation), relative to control group [%] BrdU_kidney_tce 51254

inbred

7

m

6-7wks

N=3

2014

Rusyn6

histopathology

trichloroethylene

kidney injury molecule 1 (KIM-1) positive proximal tubules [%] KIM1_kidney 51255 control TCE

inbred

7

m

6-7wks

N=4

2014

Rusyn6

drug and metabolite quantification

trichloroethylene

trichloroacetic acid (kidney TCA) [nmol/g] TCA_kidney_tce 51258

inbred

7

m

6-7wks

N=4

2014

Rusyn6

drug and metabolite quantification

trichloroethylene

dichloroacetic acid (kidney DCA) [nmol/g] DCA_kidney_tce 51260

inbred

6

m

6-7wks

N=3

2014

Rusyn6

drug and metabolite quantification

trichloroethylene

trichloroethanol (kidney TCOH) [nmol/g] TCOH_kidney_tce 51262

inbred

7

m

6-7wks

N=4

2014

Rusyn6

drug and metabolite quantification

trichloroethylene

S-(1,2-dichlorovinyl) glutathione (kidney DCVG) [pmol/g] DCVG_kidney_tce 51264

inbred

6

m

6-7wks

N=2

2014

Rusyn6

drug and metabolite quantification

trichloroethylene

S-(1,2-dichlorovinyl)-L-cysteine (kidney DCVC) [pmol/g] DCVC_kidney_tce 51266

inbred

6

m

6-7wks

N=2

2014

Rusyn6

RNA expression profiling

trichloroethylene

Acox1, mRNA in kidney, relative to control group [ratio] Acox1_kidney_tce 51268

inbred

7

m

6-7wks

N=3

2014

Rusyn6

RNA expression profiling

trichloroethylene

Cyp4a10, mRNA in kidney, relative to control group [ratio] Cyp4a10_kidney_tce 51270

inbred

7

m

6-7wks

N=3

2014

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