Pletcher1: Open field and tail suspension tests in males of 32 inbred strains of mice (2007)

Miller BH, Schultz LE, Gulati A, Su AI, Pletcher MT. Phenotypic characterization of a genetically diverse panel of mice for behavioral despair and anxiety. PLoS One. 2010 Dec 29;5(12):e14458.   PubMed 21206921     FullText


       
Pletcher1 downloads
• Download Pletcher1 project data set     one row per animal, one column per trait
• Download Pletcher1 strain means, SD, N, etc.     one row per strain/sex/measure
Participants Mathew T Pletcher       Pfizer Global Research and Development Groton, CT
With: Miller BH, Schultz LE, Gulati A, Su AI
ContactMathew T Pletcher     Mathew.Pletcher@pfizer.com     Lab web site
Part of a series: • Behavior phenotype data   (this project) Pletcher1
• Behavior phenotype data (fluoxetine study)   see Wiltshire2
• Neurobiochemical analyte data   see Wiltshire3
AcknowledgementsFunding provided NIH MH084528; and a grant from the State of Florida
Project type Phenotype strain survey data set
MPD identifiersPletcher1     MPD:360
Data changelog 2 updates/corrections.       Initial release date: 03/2011.
Formatted citation
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Summary of procedures that were conducted
• body weight
• open field test Locomotor and anxiety-related behavior. 7 min test.
• tail suspension test Immobility percentage.
• hormone quantification Corticosterone (serum).
Mice: inbred   32 strains   ♂   age 7-9wks   1 cohort

Data set MPD ID Procedure / Protocol Drug or Challenge Phenotype Measure Panel No. of Strains Sex Age Sample Size (Avg)
    Pletcher1 36001 tail suspension test (none) TST immobility percentage   [%]  TST inbred 30 m 7-10wks* N=16
    Pletcher1 36004 body weight (none) body weight   [g]  bw inbred 31 m 7-10wks* N=13
    Pletcher1 36005 hormone quantification (none) serum corticosterone, log transformed   [log(µg/dL)]  corticosterone_log inbred 29 m 7-10wks* N=6
    Pletcher1 36006 open field test (none) percent of center avoidance (thigmotaxis)   [%]  OFT_thigmotaxis inbred 31 m 7-10wks* N=15
    Pletcher1 36007 open field test (none) total distance traveled, 7 min   [cm]  OFT_activity inbred 31 m 7-10wks* N=15
    Pletcher1 36020 hormone quantification (none) serum corticosterone   [µg/dL]  corticosterone inbred 29 m 7-10wks* N=6
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