Project measures / variables set:   Paigen2   TG

ID, description, units MPD:9921   TG   triglycerides (plasma, 4h fast)   [mg/dL]  
high-fat diet study
Measures • baseline    • after 17wks on diet    • Δchange
Data set, strains Paigen2   inbred w/CC7   42 strains     sex: both     age: 7-9wks
Procedure lipid profile
Comparisonrepeated measures, baseline then treated, same cohort
Ontology mappings

  SIDE-BY-SIDE STRAIN CURVES
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  OVERLAPPING STRAIN CURVES
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Paigen2 - triglycerides (plasma, 4h fast)



  ANOVA, Q-Q NORMALITY ASSESSMENT

ANOVA Summary          "within" = Within error     "between" = Between Error (Animal ID)

Factor DF Sum of squares Mean sum of squares F value p-value (Pr>F)
between   sex 1 16987.8006 16987.8006 7.8611 0.0053
between   strain 33 1918073.0102 58123.4246 26.8966 < 0.0001
between   sex:strain 33 300502.537 9106.1375 4.2139 < 0.0001
between   Residuals 483 1043761.3509 2160.9966
within   group 1 415183.3938 415183.3938 177.0194 < 0.0001
within   group:sex 1 1969.3879 1969.3879 0.8397 0.3599
within   group:strain 33 1327570.3039 40229.4031 17.1524 < 0.0001
within   group:sex:strain 33 186429.9567 5649.3926 2.4087 < 0.0001
within   Residuals 483 1132833.9577 2345.4119

Q-Q normality assessment based on residuals

  


  INDIVIDUAL MEASURES
ProjectIDTreatmentMeasure / Variable Description PanelStrains
tested		SexAge
Paigen2 9921 lipid profile high-fat diet triglycerides (plasma, 4h fast)   [mg/dL]   baseline  TG inbred w/CC7 42 both 7-9wks
Paigen2 9922 lipid profile high-fat diet triglycerides (plasma, 4h fast)   [mg/dL]   after 17wks on diet  TG_fat17 inbred w/CC7 41 both 7-9wks
Paigen2 9923 lipid profile high-fat diet triglycerides (plasma, 4h fast)   [mg/dL]   fold change  TG_chg inbred w/CC7 41 both 7-9wks (supplemental /
  summary measure)



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