Project measure / variable:   Paigen2   TG

ID, description, units MPD:9921   TG   triglycerides (plasma, 4h fast)   [mg/dL]  baseline  
high-fat diet study
Data set, strains Paigen2   inbred w/CC7   42 strains     sex: both     age: 7-9wks
Procedure lipid profile
Ontology mappings

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  STRAIN COMPARISON PLOT
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Paigen2 - triglycerides (plasma, 4h fast) baseline



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested40 strains41 strains
Mean of the strain means119   mg/dL 137   mg/dL
Median of the strain means112   mg/dL 127   mg/dL
SD of the strain means± 53.5 ± 58.4
Coefficient of variation (CV)0.451 0.426
Min–max range of strain means48.2   –   303   mg/dL 55.2   –   352   mg/dL
Mean sample size per strain10.3   mice 12.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 81196.0742 81196.0742 41.4075 < 0.0001
strain 38 2826995.0372 74394.6062 37.939 < 0.0001
sex:strain 38 231775.0782 6099.3442 3.1105 < 0.0001
Residuals 814 1596173.371 1960.9009


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 48.2 11.6   10 3.66 0.24 25.0, 62.0 -1.31
129S1/SvImJ m 101.0 22.4   9 7.47 0.223 65.0, 124.0 -0.62
A/J f 80.9 22.0   11 6.65 0.272 54.0, 125.0 -0.7
A/J m 129.0 37.5   23 7.82 0.291 69.0, 255.0 -0.14
AKR/J f 124.0 36.2   14 9.69 0.292 62.0, 189.0 0.1
AKR/J m 108.0 26.6   9 8.88 0.246 80.0, 154.0 -0.5
BALB/cByJ f 140.0 36.1   12 10.4 0.259 85.0, 220.0 0.4
BALB/cByJ m 117.0 27.8   22 5.93 0.237 68.0, 167.0 -0.34
BTBR T+ Itpr3tf/J f 145.0 21.5   8 7.61 0.148 122.0, 183.0 0.5
BTBR T+ Itpr3tf/J m 119.0 25.1   7 9.5 0.211 100.0, 174.0 -0.31
BUB/BnJ f 132.0 55.7   11 16.8 0.421 43.0, 214.0 0.25
BUB/BnJ m 169.0 34.2   5 15.3 0.203 122.0, 212.0 0.55
C3H/HeJ f 66.4 23.3   10 7.37 0.351 40.0, 126.0 -0.97
C3H/HeJ m 92.1 27.8   26 5.46 0.302 45.0, 158.0 -0.77
C57BL/10J f 59.3 8.68   10 2.74 0.146 47.0, 70.0 -1.11
C57BL/10J m 69.4 9.24   15 2.39 0.133 53.0, 82.0 -1.16
C57BL/6J f 72.8 7.44   10 2.35 0.102 54.0, 81.0 -0.85
C57BL/6J m 100.0 25.3   10 7.99 0.252 59.0, 148.0 -0.63
C57BLKS/J f 81.3 29.5   10 9.34 0.363 51.0, 134.0 -0.7
C57BR/cdJ f 91.8 18.0   10 5.69 0.196 66.0, 119.0 -0.5
C57BR/cdJ m 68.2 9.87   12 2.85 0.145 50.0, 83.0 -1.18
C57L/J f 70.2 25.4   10 8.04 0.362 47.0, 113.0 -0.9
C57L/J m 60.1 17.4   10 5.49 0.289 46.0, 95.0 -1.32
C58/J f 84.2 31.1   5 13.9 0.37 55.0, 130.0 -0.64
C58/J m 99.8 57.9   11 17.5 0.58 42.0, 186.0 -0.64
CAST/EiJ f 113.0 59.1   9 19.7 0.521 42.0, 222.0 -0.1
CAST/EiJ m 267.0 85.9   10 27.2 0.321 63.0, 392.0 2.23
CBA/J f 113.0 22.9   8 8.09 0.202 63.0, 140.0 -0.1
CBA/J m 145.0 36.3   10 11.5 0.25 104.0, 210.0 0.14
CE/J m 159.0 43.3   9 14.4 0.271 78.0, 233.0 0.38
CZECHII/EiJ f 90.9 45.1   18 10.6 0.497 21.0, 168.0 -0.52
CZECHII/EiJ m 124.0 78.0   13 21.6 0.629 43.0, 325.0 -0.22
DBA/1J f 80.4 26.0   9 8.66 0.323 46.0, 132.0 -0.71
DBA/1J m 104.0 36.3   10 11.5 0.35 52.0, 173.0 -0.56
DBA/2J f 172.0 48.8   10 15.4 0.283 92.0, 271.0 1.0
DBA/2J m 219.0 54.0   10 17.1 0.247 146.0, 294.0 1.4
FVB/NJ f 198.0 59.4   11 17.9 0.3 81.0, 297.0 1.49
FVB/NJ m 142.0 28.9   10 9.15 0.204 110.0, 203.0 0.09
I/LnJ f 68.4 17.7   10 5.6 0.259 32.0, 87.0 -0.94
I/LnJ m 118.0 29.0   10 9.16 0.244 69.0, 165.0 -0.32
JF1/MsJ f 230.0 76.5   10 24.2 0.333 106.0, 373.0 2.08
JF1/MsJ m 200.0 50.3   14 13.5 0.251 71.0, 276.0 1.08
KK/HlJ f 228.0 60.6   10 19.2 0.266 144.0, 341.0 2.05
KK/HlJ m 245.0 62.3   8 22.0 0.254 158.0, 327.0 1.85
LP/J f 75.5 32.5   11 9.79 0.43 36.0, 142.0 -0.8
LP/J m 97.2 33.2   12 9.57 0.341 53.0, 162.0 -0.68
MA/MyJ f 119.0 35.6   10 11.3 0.298 72.0, 180.0 0.01
MA/MyJ m 129.0 35.4   10 11.2 0.274 93.0, 212.0 -0.14
MOLF/EiJ f 110.0 28.5   7 10.8 0.258 74.0, 149.0 -0.16
MOLF/EiJ m 105.0 15.3   13 4.24 0.146 75.0, 136.0 -0.55
MSM/MsJ f 114.0 28.4   8 10.0 0.248 81.0, 157.0 -0.08
MSM/MsJ m 93.0 20.6   13 5.73 0.222 44.0, 113.0 -0.75
NOD/ShiLtJ f 93.1 81.2   15 21.0 0.873 52.0, 383.0 -0.48
NOD/ShiLtJ m 96.2 24.9   12 7.18 0.258 65.0, 136.0 -0.7
NON/ShiLtJ f 303.0 44.7   10 14.1 0.148 232.0, 353.0 3.45
NON/ShiLtJ m 352.0 84.2   20 18.8 0.239 219.0, 483.0 3.68
NZB/BlNJ f 89.1 28.1   14 7.52 0.316 39.0, 147.0 -0.55
NZB/BlNJ m 138.0 29.6   10 9.35 0.214 83.0, 188.0 0.02
NZW/LacJ f 114.0 20.3   10 6.42 0.179 80.0, 141.0 -0.08
NZW/LacJ m 136.0 29.1   8 10.3 0.214 93.0, 180.0 -0.02
PERA/EiJ f 60.7 24.3   9 8.08 0.4 32.0, 96.0 -1.08
PERA/EiJ m 55.2 11.0   9 3.66 0.199 40.0, 71.0 -1.4
PL/J f 173.0 97.1   11 29.3 0.562 68.0, 415.0 1.02
PL/J m 174.0 44.8   11 13.5 0.258 109.0, 231.0 0.63
PWK/PhJ m 127.0 55.8   16 14.0 0.439 75.0, 263.0 -0.17
RF/J f 117.0 37.3   12 10.8 0.318 60.0, 194.0 -0.03
RF/J m 149.0 42.3   17 10.3 0.284 85.0, 226.0 0.21
RIIIS/J f 128.0 28.2   10 8.93 0.221 82.0, 168.0 0.18
RIIIS/J m 131.0 39.0   22 8.32 0.298 84.0, 220.0 -0.1
SEA/GnJ f 109.0 35.7   10 11.3 0.326 65.0, 160.0 -0.18
SEA/GnJ m 140.0 26.3   7 9.94 0.188 102.0, 172.0 0.05
SJL/J f 152.0 53.0   10 16.8 0.348 80.0, 243.0 0.63
SJL/J m 156.0 45.5   15 11.7 0.292 103.0, 238.0 0.33
SM/J f 184.0 44.8   9 14.9 0.243 90.0, 224.0 1.22
SM/J m 225.0 101.0   17 24.6 0.45 77.0, 519.0 1.51
SPRET/EiJ f 132.0 38.1   11 11.5 0.288 86.0, 218.0 0.25
SPRET/EiJ m 141.0 53.0   13 14.7 0.376 87.0, 234.0 0.07
SWR/J f 97.2 42.5   12 12.3 0.437 53.0, 213.0 -0.4
SWR/J m 122.0 43.1   12 12.4 0.354 69.0, 204.0 -0.26
WSB/EiJ f 79.9 14.4   8 5.1 0.18 63.0, 98.0 -0.72
WSB/EiJ m 93.9 25.9   14 6.93 0.276 58.0, 136.0 -0.74


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 48.2 14.0032 75.6867 20.7133
129S1/SvImJ m 100.6667 14.7607 129.6402 71.6932
A/J f 80.9091 13.3515 107.1166 54.7016
A/J m 128.7826 9.2334 146.9068 110.6584
AKR/J f 123.9286 11.8349 147.159 100.6981
AKR/J m 108.3333 14.7607 137.3068 79.3598
BALB/cByJ f 139.5 12.7831 164.5918 114.4082
BALB/cByJ m 117.4091 9.441 135.9406 98.8776
BTBR T+ Itpr3tf/J f 145.125 15.6561 175.856 114.394
BTBR T+ Itpr3tf/J m 119.0 16.737 151.8529 86.1471
BUB/BnJ f 132.2727 13.3515 158.4802 106.0652
BUB/BnJ m 168.8 19.8035 207.672 129.928
C3H/HeJ f 66.4 14.0032 93.8867 38.9133
C3H/HeJ m 92.0769 8.6844 109.1234 75.0304
C57BL/10J f 59.3 14.0032 86.7867 31.8133
C57BL/10J m 69.4 11.4336 91.8428 46.9572
C57BL/6J f 72.8 14.0032 100.2867 45.3133
C57BL/6J m 100.4 14.0032 127.8867 72.9133
C57BR/cdJ f 91.8 14.0032 119.2867 64.3133
C57BR/cdJ m 68.25 12.7831 93.3418 43.1582
C57L/J f 70.2 14.0032 97.6867 42.7133
C57L/J m 60.1 14.0032 87.5867 32.6133
C58/J f 84.2 19.8035 123.072 45.328
C58/J m 99.8182 13.3515 126.0257 73.6107
CAST/EiJ f 113.4444 14.7607 142.4179 84.4709
CAST/EiJ m 267.3 14.0032 294.7867 239.8133
CBA/J f 113.125 15.6561 143.856 82.394
CBA/J m 145.0 14.0032 172.4867 117.5133
CZECHII/EiJ f 90.8889 10.4374 111.3762 70.4015
CZECHII/EiJ m 123.9231 12.2816 148.0305 99.8157
DBA/1J f 80.4444 14.7607 109.4179 51.4709
DBA/1J m 103.6 14.0032 131.0867 76.1133
DBA/2J f 172.1 14.0032 199.5867 144.6133
DBA/2J m 218.6 14.0032 246.0867 191.1133
FVB/NJ f 197.5455 13.3515 223.753 171.3379
FVB/NJ m 141.9 14.0032 169.3867 114.4133
I/LnJ f 68.4 14.0032 95.8867 40.9133
I/LnJ m 118.5 14.0032 145.9867 91.0133
JF1/MsJ f 229.6 14.0032 257.0867 202.1133
JF1/MsJ m 200.4286 11.8349 223.659 177.1981
KK/HlJ f 227.8 14.0032 255.2867 200.3133
KK/HlJ m 245.25 15.6561 275.981 214.519
LP/J f 75.5455 13.3515 101.753 49.3379
LP/J m 97.25 12.7831 122.3418 72.1582
MA/MyJ f 119.4 14.0032 146.8867 91.9133
MA/MyJ m 129.2 14.0032 156.6867 101.7133
MOLF/EiJ f 110.4286 16.737 143.2814 77.5757
MOLF/EiJ m 105.0 12.2816 129.1074 80.8926
MSM/MsJ f 114.5 15.6561 145.231 83.769
MSM/MsJ m 93.0 12.2816 117.1074 68.8926
NOD/ShiLtJ f 93.0667 11.4336 115.5094 70.6239
NOD/ShiLtJ m 96.1667 12.7831 121.2584 71.0749
NON/ShiLtJ f 302.8 14.0032 330.2867 275.3133
NON/ShiLtJ m 351.85 9.9018 371.286 332.414
NZB/BlNJ f 89.0714 11.8349 112.3019 65.841
NZB/BlNJ m 138.3 14.0032 165.7867 110.8133
NZW/LacJ f 113.6 14.0032 141.0867 86.1133
NZW/LacJ m 136.25 15.6561 166.981 105.519
PERA/EiJ f 60.6667 14.7607 89.6402 31.6932
PERA/EiJ m 55.2222 14.7607 84.1957 26.2487
PL/J f 172.7273 13.3515 198.9348 146.5198
PL/J m 173.5455 13.3515 199.753 147.3379
RF/J f 117.3333 12.7831 142.4251 92.2416
RF/J m 149.2353 10.74 170.3166 128.154
RIIIS/J f 127.7 14.0032 155.1867 100.2133
RIIIS/J m 131.0909 9.441 149.6224 112.5594
SEA/GnJ f 109.4 14.0032 136.8867 81.9133
SEA/GnJ m 140.2857 16.737 173.1386 107.4329
SJL/J f 152.1 14.0032 179.5867 124.6133
SJL/J m 155.8 11.4336 178.2428 133.3572
SM/J f 184.2222 14.7607 213.1957 155.2487
SM/J m 225.4706 10.74 246.5519 204.3893
SPRET/EiJ f 132.3636 13.3515 158.5711 106.1561
SPRET/EiJ m 141.0769 12.2816 165.1843 116.9695
SWR/J f 97.25 12.7831 122.3418 72.1582
SWR/J m 121.9167 12.7831 147.0084 96.8249
WSB/EiJ f 79.875 15.6561 110.606 49.144
WSB/EiJ m 93.9286 11.8349 117.159 70.6981


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 74.4333 10.1731 94.4019 54.4647
A/J both 104.8458 8.1167 120.7779 88.9138
AKR/J both 116.131 9.4597 134.6992 97.5627
BALB/cByJ both 128.4545 7.9458 144.0511 112.858
BTBR T+ Itpr3tf/J both 132.0625 11.4591 154.5553 109.5697
BUB/BnJ both 150.5364 11.942 173.9771 127.0957
C3H/HeJ both 79.2385 8.2388 95.4102 63.0667
C57BL/10J both 64.35 9.039 82.0926 46.6074
C57BL/6J both 86.6 9.9018 106.036 67.164
C57BR/cdJ both 80.025 9.4802 98.6336 61.4164
C57L/J both 65.15 9.9018 84.586 45.714
C58/J both 92.0091 11.942 115.4498 68.5684
CAST/EiJ both 190.3722 10.1731 210.3408 170.4036
CBA/J both 129.0625 10.5024 149.6775 108.4475
CZECHII/EiJ both 107.406 8.0588 123.2245 91.5875
DBA/1J both 92.0222 10.1731 111.9908 72.0536
DBA/2J both 195.35 9.9018 214.786 175.914
FVB/NJ both 169.7227 9.6741 188.7119 150.7336
I/LnJ both 93.45 9.9018 112.886 74.014
JF1/MsJ both 215.0143 9.1673 233.0085 197.02
KK/HlJ both 236.525 10.5024 257.14 215.91
LP/J both 86.3977 9.2422 104.5391 68.2564
MA/MyJ both 124.3 9.9018 143.736 104.864
MOLF/EiJ both 107.7143 10.3799 128.0888 87.3398
MSM/MsJ both 103.75 9.9493 123.2792 84.2208
NOD/ShiLtJ both 94.6167 8.5752 111.4487 77.7846
NON/ShiLtJ both 327.325 8.5752 344.1571 310.4929
NZB/BlNJ both 113.6857 9.1673 131.68 95.6915
NZW/LacJ both 124.925 10.5024 145.54 104.31
PERA/EiJ both 57.9444 10.4374 78.4318 37.4571
PL/J both 173.1364 9.441 191.6679 154.6049
RF/J both 133.2843 8.348 149.6704 116.8982
RIIIS/J both 129.3955 8.4443 145.9705 112.8204
SEA/GnJ both 124.8429 10.9112 146.2603 103.4254
SJL/J both 153.95 9.039 171.6926 136.2074
SM/J both 204.8464 9.1272 222.7621 186.9307
SPRET/EiJ both 136.7203 9.0706 154.5248 118.9158
SWR/J both 109.5833 9.039 127.3259 91.8408
WSB/EiJ both 86.9018 9.813 106.1635 67.6401




  GWAS USING LINEAR MIXED MODELS