MPD: Project measures / variables set: Mills1 retic

Project measures / variables set: Mills1 retic_micronucl

ID, description, units	MPD:25225 retic_micronucl reticulocytes with micronuclei [%]
Measures	• 6mo • 12mo • 20mo
Data set, strains	Mills1 inbred 30 strains sex: both
Procedure	chromosome instability assessment
Comparison	aging-study, multiple cohorts
Ontology mappings	VT:0002447 erythrocyte morphology trait MA:0000059 blood MP:0002424 abnormal reticulocyte morphology MP:0008866 chromosomal instability

Values Means Δ Means Z-scores

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Mills1 - reticulocytes with micronuclei

ANOVA, Q-Q NORMALITY ASSESSMENT

ANOVA Summary

Factor	DF	Sum of squares	Mean sum of squares	F value	p-value (Pr>F)
age	2	0.0069	0.0035	1.0255	0.366
age:sex	2	0.0121	0.006	1.7818	0.1789
age:sex:strain	2	0.008	0.004	1.1781	0.3163
age:strain	2	0.0111	0.0056	1.6415	0.204
Residuals	50	0.1692	0.0034
sex	1	0.0001	0.0001	0.03	0.8631
sex:strain	1	0.0003	0.0003	0.1018	0.7511
strain	1	0.0015	0.0015	0.4574	0.5019

Q-Q normality assessment based on residuals

INDIVIDUAL MEASURES

Project	ID		Treatment	Measure / Variable Description	Panel	Strains tested	Sex	Age
Mills1	25225	chromosome instability assessment	(none)	reticulocytes with micronuclei [%] at age 6mo retic_micronucl_M06	inbred	7	both	26wks
Mills1	25226	chromosome instability assessment	(none)	reticulocytes with micronuclei [%] at age 12mo retic_micronucl_M12	inbred	30	both	52wks
Mills1	25227	chromosome instability assessment	(none)	reticulocytes with micronuclei [%] at age 20mo retic_micronucl_M20	inbred	25	both	87wks