Project measure / variable:   Mills1   retic_micronucl_M20

ID, description, units MPD:25227   retic_micronucl_M20   reticulocytes with micronuclei   [%]  at age 20mo  
Data set, strains Mills1   inbred   25 strains     sex: both     age: 87wks
Procedure chromosome instability assessment
Ontology mappings

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  STRAIN COMPARISON PLOT
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Mills1 - reticulocytes with micronuclei at age 20mo



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested23 strains22 strains
Mean of the strain means0.0413   % 0.0313   %
Median of the strain means0.0325   % 0.0300   %
SD of the strain means± 0.0269 ± 0.0162
Coefficient of variation (CV)0.652 0.518
Min–max range of strain means0.0150   –   0.115   % 0.00950   –   0.0670   %
Mean sample size per strain5.3   mice 4.3   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.0082 0.0082 4.3078 0.0397
strain 17 0.0692 0.0041 2.1438 0.008
sex:strain 17 0.0241 0.0014 0.7455 0.7516
Residuals 145 0.2752 0.0019


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 0.0255 0.0101   6 0.00412 0.396 0.012, 0.041 -0.59
129S1/SvImJ m 0.017 0.00515   5 0.0023 0.303 0.009, 0.022 -0.88
A/J f 0.0153 0.00643   3 0.00371 0.419 0.008, 0.02 -0.97
A/J m 0.0193 0.0117   3 0.00674 0.604 0.009, 0.032 -0.74
BALB/cByJ f 0.0228 0.00756   5 0.00338 0.332 0.015, 0.032 -0.69
BTBR T+ Itpr3tf/J f 0.072 0.0525   7 0.0198 0.729 0.033, 0.17 1.14
BTBR T+ Itpr3tf/J m 0.057 0.0293   4 0.0146 0.514 0.034, 0.098 1.58
BUB/BnJ f 0.0514 0.0326   5 0.0146 0.634 0.02, 0.1 0.37
BUB/BnJ m 0.031 0.0   1   0.0 0.0 0.031, 0.031 -0.02
C3H/HeJ f 0.023 0.00744   4 0.00372 0.323 0.016, 0.033 -0.68
C3H/HeJ m 0.031 0.0186   6 0.00761 0.601 0.013, 0.06 -0.02
C57BL/10J f 0.0372 0.0133   5 0.00594 0.357 0.023, 0.05 -0.15
C57BL/10J m 0.0262 0.0231   6 0.00944 0.884 0.011, 0.072 -0.31
C57BL/6J f 0.0227 0.00916   6 0.00374 0.404 0.013, 0.036 -0.69
C57BLKS/J m 0.0415 0.0148   2   0.0105 0.358 0.031, 0.052 0.63
C57BR/cdJ f 0.089 0.11   6 0.045 1.24 0.014, 0.3 1.77
C57BR/cdJ m 0.0472 0.024   9 0.008 0.508 0.022, 0.087 0.98
C57L/J f 0.015 0.00949   6 0.00387 0.632 0.003, 0.03 -0.98
C57L/J m 0.0397 0.0259   6 0.0106 0.652 0.01, 0.083 0.52
CBA/J m 0.0103 0.00197   6 0.000803 0.19 0.008, 0.013 -1.29
DBA/2J f 0.0325 0.0094   6 0.00384 0.289 0.021, 0.048 -0.33
DBA/2J m 0.039 0.0121   4 0.00607 0.311 0.028, 0.05 0.48
FVB/NJ f 0.0338 0.0167   6 0.00683 0.494 0.009, 0.046 -0.28
FVB/NJ m 0.0372 0.00898   5 0.00402 0.241 0.026, 0.045 0.36
KK/HlJ f 0.0336 0.00796   7 0.00301 0.237 0.027, 0.051 -0.29
KK/HlJ m 0.027 0.0127   2   0.009 0.471 0.018, 0.036 -0.26
LP/J f 0.0174 0.00945   5 0.00423 0.543 0.009, 0.032 -0.89
LP/J m 0.0117 0.00914   6 0.00373 0.783 0.004, 0.027 -1.21
MRL/MpJ f 0.0235 0.00495   2   0.0035 0.211 0.02, 0.027 -0.66
MRL/MpJ m 0.0095 0.00212   2   0.0015 0.223 0.008, 0.011 -1.34
NOD.B10Sn-H2b/J f 0.0566 0.0357   5 0.0159 0.63 0.027, 0.11 0.57
NOD.B10Sn-H2b/J m 0.059 0.0509   2   0.036 0.863 0.023, 0.095 1.71
NON/ShiLtJ f 0.0853 0.0345   7 0.013 0.404 0.028, 0.13 1.63
NON/ShiLtJ m 0.067 0.0198   2   0.014 0.296 0.053, 0.081 2.2
P/J f 0.0246 0.0152   5 0.00682 0.62 0.013, 0.05 -0.62
P/J m 0.011 0.0   1   0.0 0.0 0.011, 0.011 -1.25
PL/J f 0.0612 0.036   5 0.0161 0.589 0.033, 0.12 0.74
PWD/PhJ f 0.0235 0.00766   6 0.00313 0.326 0.015, 0.035 -0.66
PWD/PhJ m 0.029 0.0139   8 0.00493 0.481 0.015, 0.053 -0.14
RIIIS/J f 0.045 0.0129   5 0.00577 0.287 0.027, 0.061 0.14
RIIIS/J m 0.0208 0.0113   6 0.0046 0.541 0.007, 0.038 -0.65
SM/J f 0.115 0.198   5 0.0888 1.72 0.018, 0.47 2.74
SM/J m 0.0342 0.00898   5 0.00402 0.263 0.021, 0.046 0.18
WSB/EiJ f 0.0243 0.00503   3 0.00291 0.207 0.019, 0.029 -0.63
WSB/EiJ m 0.0228 0.0109   6 0.00447 0.479 0.014, 0.044 -0.52


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 0.0255 0.0178 0.0607 0.0
129S1/SvImJ m 0.017 0.0195 0.0555 0.0
A/J f 0.0153 0.0252 0.065 0.0
A/J m 0.0193 0.0252 0.069 0.0
BTBR T+ Itpr3tf/J f 0.072 0.0165 0.1045 0.0395
BTBR T+ Itpr3tf/J m 0.057 0.0218 0.1 0.014
C3H/HeJ f 0.023 0.0218 0.066 0.0
C3H/HeJ m 0.031 0.0178 0.0662 0.0
C57BL/10J f 0.0372 0.0195 0.0757 0.0
C57BL/10J m 0.0262 0.0178 0.0613 0.0
C57BR/cdJ f 0.089 0.0178 0.1242 0.0538
C57BR/cdJ m 0.0472 0.0145 0.0759 0.0185
C57L/J f 0.015 0.0178 0.0502 0.0
C57L/J m 0.0397 0.0178 0.0748 0.0045
DBA/2J f 0.0325 0.0178 0.0677 0.0
DBA/2J m 0.039 0.0218 0.082 0.0
FVB/NJ f 0.0338 0.0178 0.069 0.0
FVB/NJ m 0.0372 0.0195 0.0757 0.0
KK/HlJ f 0.0336 0.0165 0.0661 0.001
KK/HlJ m 0.027 0.0308 0.0879 0.0
LP/J f 0.0174 0.0195 0.0559 0.0
LP/J m 0.0117 0.0178 0.0468 0.0
MRL/MpJ f 0.0235 0.0308 0.0844 0.0
MRL/MpJ m 0.0095 0.0308 0.0704 0.0
NOD.B10Sn-H2b/J f 0.0566 0.0195 0.0951 0.0181
NOD.B10Sn-H2b/J m 0.059 0.0308 0.1199 0.0
NON/ShiLtJ f 0.0853 0.0165 0.1178 0.0527
NON/ShiLtJ m 0.067 0.0308 0.1279 0.0061
PWD/PhJ f 0.0235 0.0178 0.0587 0.0
PWD/PhJ m 0.029 0.0154 0.0594 0.0
RIIIS/J f 0.045 0.0195 0.0835 0.0065
RIIIS/J m 0.0208 0.0178 0.056 0.0
SM/J f 0.1152 0.0195 0.1537 0.0767
SM/J m 0.0342 0.0195 0.0727 0.0
WSB/EiJ f 0.0243 0.0252 0.074 0.0
WSB/EiJ m 0.0228 0.0178 0.058 0.0


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 0.0213 0.0132 0.0473 0.0
A/J both 0.0173 0.0178 0.0525 0.0
BTBR T+ Itpr3tf/J both 0.0645 0.0137 0.0915 0.0375
C3H/HeJ both 0.027 0.0141 0.0548 0.0
C57BL/10J both 0.0317 0.0132 0.0578 0.0056
C57BR/cdJ both 0.0681 0.0115 0.0908 0.0454
C57L/J both 0.0273 0.0126 0.0522 0.0025
DBA/2J both 0.0358 0.0141 0.0635 0.008
FVB/NJ both 0.0355 0.0132 0.0616 0.0094
KK/HlJ both 0.0303 0.0175 0.0648 0.0
LP/J both 0.0145 0.0132 0.0406 0.0
MRL/MpJ both 0.0165 0.0218 0.0595 0.0
NOD.B10Sn-H2b/J both 0.0578 0.0182 0.0938 0.0218
NON/ShiLtJ both 0.0761 0.0175 0.1107 0.0416
PWD/PhJ both 0.0263 0.0118 0.0495 0.003
RIIIS/J both 0.0329 0.0132 0.059 0.0068
SM/J both 0.0747 0.0138 0.1019 0.0475
WSB/EiJ both 0.0236 0.0154 0.054 0.0




  GWAS USING LINEAR MIXED MODELS