MPD: Project measures / variables set: Jaxpheno3 CHOL

Project measures / variables set: Jaxpheno3 CHOL

ID, description, units	MPD:22830 CHOL cholesterol (plasma CHOL) [mg/dL]
Measures	• age 8wks • age 16wks
Data set, strains	Jaxpheno3 inbred 11 strains sex: both
Procedure	lipid profile
Comparison	multiple cohorts measured at two age timepoints
Ontology mappings	VT:0000180 blood cholesterol amount MA:0002501 plasma MP:0000180 abnormal circulating cholesterol level

Values Means Δ Means Z-scores

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Jaxpheno3 - cholesterol (plasma CHOL)

ANOVA, Q-Q NORMALITY ASSESSMENT

ANOVA Summary

Factor	DF	Sum of squares	Mean sum of squares	F value	p-value (Pr>F)
age	1	64.61	64.61	0.1556	0.6934
age:sex	1	2477.5921	2477.5921	5.9665	0.0149
age:sex:strain	7	13906.137	1986.591	4.784	< 0.0001
age:strain	7	21260.3432	3037.1919	7.3141	< 0.0001
Residuals	545	226313.1238	415.2534
sex	1	78099.8131	78099.8131	188.0775	< 0.0001
sex:strain	7	14911.5617	2130.2231	5.1299	< 0.0001
strain	7	58220.424	8317.2034	20.0292	< 0.0001

Q-Q normality assessment based on residuals

INDIVIDUAL MEASURES

Project	ID		Treatment	Measure / Variable Description	Panel	Strains tested	Sex	Age
Jaxpheno3	22830	lipid profile	(none)	cholesterol (plasma CHOL) [mg/dL] at age 8wks CHOL8	inbred	11	both	8wks
Jaxpheno3	22831	lipid profile	(none)	cholesterol (plasma CHOL) [mg/dL] at age 16wks CHOL16	inbred	8	both	16wks