Phenotype >
| Project data set: Wiltshire2 (2011) |
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| | Project |
Drug study: Behavioral responses to chronic fluoxetine treatment in males of 30 inbred mouse strains
Behaviors related to anxiety or mood disorders were assessed to identify biomarkers of anti-depressant responses by comparing behavioral phenotypes to neurobiochemical analyte levels
(Wiltshire3)
between two cohorts: 1) vehicle (control), and 2) fluoxetine (chronic treatment).
Study design:
control vs. intervention;
2 cohorts.
30 strains tested
only
Test age:
9-11wks
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| Investigators |
Wiltshire T, Pletcher MT
[Details, papers]
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| Part of a series: |
• Behavior phenotype data ... see Pletcher1
• Behavior phenotype data (fluoxetine study) ... this project ... Wiltshire2
• Neurobiochemical analyte data ... see Wiltshire3
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| Protocol |
View phenotyping protocol and methods
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Wiltshire2
measurements
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Number of mice tested per strain, for each measurement
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| Changelog |
There have been no updates or corrections
to the data set since MPD release
in
Dec 2011
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| Reference |
Benton CS, Miller BH, Skwerer S, Suzuki O, Schultz LE, Cameron MD, Marron JS, Pletcher MT, Wiltshire T. Evaluating genetic markers and neurobiochemical analytes for fluoxetine response using a panel of mouse inbred strains.
Psychopharmacology (Berl). 2012 May;221(2):297-315. Epub 2011 Nov 24.
PubMed 22113448
MGI
FullText
Related papers
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| Mice |
Strain and animal info
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| Note |
Some measurements were derived by MPD staff,
based on supplied data. [View list]
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Wiltshire2
downloads
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See also the MPD download center for more general data download options.
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