|Project data set: Wiltshire2 (2011)|
Drug study: Behavioral responses to chronic fluoxetine treatment in males of 30 inbred mouse strains
Behaviors related to anxiety or mood disorders were assessed to identify biomarkers of anti-depressant responses by comparing behavioral phenotypes to neurobiochemical analyte levels
between two cohorts: 1) vehicle (control), and 2) fluoxetine (chronic treatment).
control vs. intervention;
30 strains tested
Wiltshire T, Pletcher MT
|Part of a series:||
• Behavior phenotype data ... see Pletcher1|
• Behavior phenotype data (fluoxetine study) ... this project ... Wiltshire2
• Neurobiochemical analyte data ... see Wiltshire3
View phenotyping protocol and methods
Number of mice tested per strain, for each measurement
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There have been no updates or corrections
to the data set since MPD release
Benton CS, Miller BH, Skwerer S, Suzuki O, Schultz LE, Cameron MD, Marron JS, Pletcher MT, Wiltshire T. Evaluating genetic markers and neurobiochemical analytes for fluoxetine response using a panel of mouse inbred strains.
Psychopharmacology (Berl). 2012 May;221(2):297-315. Epub 2011 Nov 24.
Strain and animal info
Some measurements were derived by MPD staff,
based on supplied data. [View list]
See also the MPD download center for more general data download options.