Rating scale for wildness and ease of handling. Rating scales for difficulty in capturing and holding mice were devised to provide an impression of the difficulties encountered while working with common laboratory strains and four wild-derived inbred strains.

Available measurements   Mice & strains       Protocol       Plots & tools wizard Change list style       Show varnames       Verbose listing       Display strain data     Compare 2 strains behavior — wildness   Wahlsten2 number of tests [score]         with:             • sqeaks              • bites              • escapes              • placid (no wildness events)              21 strains   age 10-12wks Wahlsten2 overall mean ratings [score]         • capture rating        • hold rating        21 strains   age 10-12wks Wahlsten2 wildness rating [score]         during:             • capture and hold              • OF and EPM              • rotarod              • water escape              • weighing              21 strains   age 10-12wks Display strain means in the above table for: select a strain 129S1/SvImJ A/J AKR/J BALB/cByJ BTBR T+ tf/J C3H/HeJ C57BL/6J C57L/J C58/J CAST/EiJ DBA/2J FVB/NJ MOLF/EiJ NOD/ShiLtJ NZB/BlNJ PERA/EiJ PL/J SJL/J SM/J SPRET/EiJ SWR/J   Compare two strains: select strain 1 129S1/SvImJ A/J AKR/J BALB/cByJ BTBR T+ tf/J C3H/HeJ C57BL/6J C57L/J C58/J CAST/EiJ DBA/2J FVB/NJ MOLF/EiJ NOD/ShiLtJ NZB/BlNJ PERA/EiJ PL/J SJL/J SM/J SPRET/EiJ SWR/J vs. select strain 2 129S1/SvImJ A/J AKR/J BALB/cByJ BTBR T+ tf/J C3H/HeJ C57BL/6J C57L/J C58/J CAST/EiJ DBA/2J FVB/NJ MOLF/EiJ NOD/ShiLtJ NZB/BlNJ PERA/EiJ PL/J SJL/J SM/J SPRET/EiJ SWR/J   Compare female vs. male for: select a strain 129S1/SvImJ A/J AKR/J BALB/cByJ BTBR T+ tf/J C3H/HeJ C57BL/6J C57L/J C58/J CAST/EiJ DBA/2J FVB/NJ MOLF/EiJ NOD/ShiLtJ NZB/BlNJ PERA/EiJ PL/J SJL/J SM/J SPRET/EiJ SWR/J   Display overall measurement averages (all strains combined) in the above table

Notes

Wahlsten D, Metten P, Crabbe JC. A rating scale for wildness and ease of handling laboratory mice: results for 21 inbred strains tested in two laboratories. Genes Brain Behav. 2003 Apr;2(2):71-9.     PubMed    MGI There have been no updates or corrections to the dataset since it was first released in Mar, 2004 This study was conducted on the same set of mice tested for several behavioral parameters and examined for brain defects (Wahlsten1). Missing data code clarifications: DI = died; always occurred in home cage in colony room, never during the actual test ND = no data; almost always occurred because technician failed to record rating PP = physical problem; for strain C58/J, trial was stopped when they sank in water maze OT = other; average undefined because of missing values Some strain means have N < 5 animals (click for table).

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The Wahlsten2 project data set. Individual animal data in table format, with one row per animal and measurements organized as columns. Excel file Wahlsten2 individual animal data in list format. Most or all of the same information* as the file above, but organized as one row per animal / measurement. Excel file Wahlsten2 strain means, SD, SEM, N, Z-scores and other summary statistics. One row per strain / sex / measurement. Excel file These Excel files include data, descriptions, and units for all measurements listed above. Other download options are available via the Plots & Tools Wizard, above. Wahlsten2 protocol document HTML Wahlsten2 animal documentation HTML Supplemental data are available Click here for more info