Bachmanov1: NaCl taste thresholds in males of 13 inbred mouse strains (2011)

Ishiwatari Y, Bachmanov AA. NaCl taste thresholds in 13 inbred mouse strains. Chem Senses. 2012 Jul;37(6):497-508. Epub 2012 Jan 31.   PubMed 22293936     FullText


       
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Participants Alexander A Bachmanov       Monell Chemical Senses Center Philadelphia, PA
With: Ishiwatari Y
ContactAlexander A Bachmanov     bachmanov@monell.org     Lab web site
AffiliationMonell Chemical Senses Center
AcknowledgementsFunding provided by NIH DC000882; Ajinomoto Inc., Firmenich SA, Givaudan SA, and International Flavors and Fragrances Inc.
Project type Phenotype strain survey data set
MPD identifiersBachmanov1     MPD:404
Data changelog No updates/corrections.       Initial release date: 05/2012.
Formatted citation
Click above to copy-paste the entire citation for this MPD web page.
Mice were evaluated using a high-throughput procedure to measure NaCl taste thresholds involving conditioned taste aversion (CTA), with oral self-administration of 150 mM LiCl as a conditioned stimulus followed by a series of 48-h two-bottle preference tests with increasing concentrations of NaCl.

Summary of procedures that were conducted
• intake monitoring Water intake. Daily.
• bottle choice test Sodium chloride solution taste threshold. Fluid intake.
• body weight
Mice: inbred   13 strains   ♂   age 7-8wks   1 cohort

Data set MPD ID Procedure / Protocol Drug or Challenge Phenotype Measure Panel No. of Strains Sex Age Sample Size (Avg)
    Bachmanov1 40401 intake monitoring (none) water intake   [mL]     daily    daily adj for body weight inbred 13 m 7-8wks N=10
    Bachmanov1 40403 bottle choice test (none) sodium chloride (NaCl) solution taste threshold   [mM]  NaCl_threshold inbred 13 m 7-8wks N=10
    Bachmanov1 40404 body weight (none) body weight   [g]  bw inbred 13 m 7-8wks N=10
    All boxes