MPD: Project measures / variables set: Jentsch2 discrimination

Project measures / variables set: Jentsch2 discrimination_FR1

ID, description, units	MPD:49706 discrimination_FR1 Fixed ratio 1 - discrimination index between active and inactive levers [%] cocaine study
Measures	• day 1 • day 3 • day 5 • last day
Data set, strains	Jentsch2 BXD 4 strains sex: both age: 8-17wks
Procedure	operant conditioning chamber
Comparison	repeated measures, set of trials, same cohort
Ontology mappings	VT:0002063 learning/memory/conditioning trait VT:0010473 impulsivity behavior trait VT:0010531 operant conditioning behavior trait VT:0010718 response to cocaine trait MP:0001988 cocaine preference MP:0002803 abnormal operant conditioning behavior MP:0010698 abnormal impulsive behavior control MP:0020158 abnormal behavioral response to cocaine

Values Means Δ Means Z-scores

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Jentsch2 - Fixed ratio 1 - discrimination index between active and inactive levers

ANOVA Summary "within" = Within error "between" = Between Error (Animal ID)

Factor	DF	Sum of squares	Mean sum of squares	F value	p-value (Pr>F)
between sex	1	5259.9714	5259.9714	11.5069	0.0035
between strain	1	77.885	77.885	0.1704	0.6849
between sex:strain	1	35.4178	35.4178	0.0775	0.7841
between Residuals	17	7770.9522	457.1148
within group	3	4177.0365	1392.3455	4.3618	0.0083
within group:sex	3	3454.0648	1151.3549	3.6068	0.0194
within group:strain	3	258.7137	86.2379	0.2702	0.8466
within group:sex:strain	3	751.887	250.629	0.7851	0.5078
within Residuals	51	16280.0147	319.216

Q-Q normality assessment based on residuals

INDIVIDUAL MEASURES

Project	ID		Treatment	Measure / Variable Description	Panel	Strains tested	Sex	Age
Jentsch2	49706	operant conditioning chamber	cocaine	Fixed ratio 1 - discrimination index between active and inactive levers [%] day 1 discrimination1_FR1	BXD	4	both	8-17wks
Jentsch2	49707	operant conditioning chamber	cocaine	Fixed ratio 1 - discrimination index between active and inactive levers [%] day 3 discrimination3_FR1	BXD	4	both	8-17wks
Jentsch2	49708	operant conditioning chamber	cocaine	Fixed ratio 1 - discrimination index between active and inactive levers [%] day 5 discrimination5_FR1	BXD	4	both	8-17wks
Jentsch2	49709	operant conditioning chamber	cocaine	Fixed ratio 1 - discrimination index between active and inactive levers [%] last day discrimination_last_FR1	BXD	4	both	8-17wks