MPD: Project measures / variables set: Rusyn5 liver

Project measures / variables set: Rusyn5 liver_GSSG

ID, description, units	MPD:43025 liver_GSSG oxidized liver glutathione (GSSG) [nmol/mg] high-fat diet and ethanol study
Measures	• high-fat only • high-fat and ethanol
Data set, strains	Rusyn5 inbred 14 strains sex: m age: 8-14wks
Procedure	metabolite quantification
Comparison	control group vs. treated group
Ontology mappings	VT:0000609 liver physiology trait VT:0010489 response to alcohol trait VT:0010516 blood glutathione amount MA:0000358 liver MP:0011601 abnormal glutathione peroxidase activity

Values Means Δ Means Z-scores

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Rusyn5 - oxidized liver glutathione (GSSG)

ANOVA, Q-Q NORMALITY ASSESSMENT

ANOVA Summary

Factor	DF	Sum of squares	Mean sum of squares	F value	p-value (Pr>F)
group	1	3.0633	3.0633	11.6275	0.0012
group:strain	13	4.9479	0.3806	1.4447	0.1692
Residuals	55	14.4897	0.2634
strain	13	10.4156	0.8012	3.0412	0.002

Q-Q normality assessment based on residuals

INDIVIDUAL MEASURES

Project	ID		Treatment	Measure / Variable Description	Panel	Strains tested	Sex	Age
Rusyn5	43025	metabolite quantification	high-fat diet and ethanol	oxidized liver glutathione (GSSG) [nmol/mg] high-fat only liver_GSSG_hf	inbred	14	m	8-14wks
Rusyn5	43026	metabolite quantification	high-fat diet and ethanol	oxidized liver glutathione (GSSG) [nmol/mg] high-fat and ethanol liver_GSSG_hfe	inbred	14	m	8-14wks