Project measure / variable:   Palmer5   PPI

ID, description, units MPD:59732   PPI   percentage prepulse inhibition (PPI) evoked by 120 dB sound pressure level with 6 dB prepulse stimulus   [%]  
Data set, strains Palmer5   F1 Tcf7l2   30 strains     sex: both     age: 7-14wks
Procedure acoustic startle test
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  STRAIN COMPARISON PLOT
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Palmer5 - percentage prepulse inhibition (PPI) evoked by 120 dB sound pressure level with 6 dB prepulse stimulus



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested30 strains30 strains
Mean of the strain means50.4   % 50.8   %
Median of the strain means52.5   % 51.6   %
SD of the strain means± 11.1 ± 10.2
Coefficient of variation (CV)0.221 0.200
Min–max range of strain means27.9   –   74.7   % 29.1   –   73.2   %
Mean sample size per strain5.0   mice 5.1   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.0633 0.0633 0.0002 0.9881
strain 29 30614.6416 1055.6773 3.7061 < 0.0001
sex:strain 29 5009.4171 172.7385 0.6064 0.9462
Residuals 246 70072.685 284.8483


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129SB6F1 f 54.1 7.89   6 3.22 0.146 39.2, 60.5 0.33
129SB6F1 m 51.9 17.7   5 7.94 0.342 29.0, 72.9 0.11
AB6F1 f 57.7 12.8   3 7.41 0.222 43.0, 66.5 0.65
AB6F1 m 58.9 13.1   4 6.55 0.223 47.8, 75.6 0.8
AKB6F1 f 57.2 6.68   4 3.34 0.117 50.6, 65.9 0.61
AKB6F1 m 53.4 7.5   2   5.3 0.14 48.1, 58.7 0.26
BKSB6F1 f 57.2 15.8   5 7.06 0.276 30.5, 69.9 0.61
BKSB6F1 m 73.2 10.4   6 4.25 0.142 54.4, 82.2 2.21
BTBRB6F1 f 55.9 20.9   4 10.4 0.373 25.7, 71.7 0.49
BTBRB6F1 m 53.2 8.63   4 4.32 0.162 41.6, 60.6 0.24
BUB6F1 f 72.4 13.5   7 5.09 0.186 50.5, 88.2 1.97
BUB6F1 m 64.3 20.8   5 9.3 0.323 29.5, 84.5 1.33
C3B6F1 f 52.5 22.6   4 11.3 0.431 29.9, 75.4 0.19
C3B6F1 m 35.1 12.1   4 6.04 0.344 20.8, 47.4 -1.55
C57BL/6J f 71.4 6.28   8 2.22 0.088 61.5, 82.2 1.88
C57BL/6J m 69.1 9.27   9 3.09 0.134 53.1, 85.8 1.8
C57LB6F1 f 53.4 14.8   7 5.58 0.276 32.6, 69.5 0.27
C57LB6F1 m 52.9 19.5   5 8.7 0.367 27.8, 79.9 0.21
C58B6F1 f 46.3 14.5   6 5.94 0.314 19.7, 60.5 -0.37
C58B6F1 m 51.4 7.45   3 4.3 0.145 46.5, 60.0 0.06
CBAB6F1 f 57.7 10.3   5 4.61 0.179 40.8, 67.6 0.65
CBAB6F1 m 53.4 4.58   4 2.29 0.0859 46.5, 56.1 0.26
CByB6F1 f 38.0 9.04   4 4.52 0.238 26.8, 48.9 -1.11
CByB6F1 m 52.1 14.6   4 7.29 0.28 40.1, 73.1 0.13
D2B6F1 f 53.7 6.92   5 3.1 0.129 43.1, 59.8 0.3
D2B6F1 m 52.6 31.3   5 14.0 0.595 -1.1, 77.6 0.18
DDYB6F1 f 74.7 8.03   4 4.01 0.107 67.1, 82.1 2.18
DDYB6F1 m 64.5 16.3   5 7.28 0.252 46.4, 82.4 1.35
FVBB6F1 f 56.7 5.56   5 2.49 0.0981 48.4, 62.6 0.56
FVBB6F1 m 56.1 12.5   7 4.73 0.223 38.5, 71.3 0.52
IB6F1 f 39.5 18.6   6 7.59 0.47 10.6, 56.0 -0.98
IB6F1 m 47.3 18.0   6 7.33 0.379 15.1, 67.6 -0.35
KKB6F1 f 28.5 20.1   4 10.1 0.708 7.4, 54.2 -1.97
KKB6F1 m 35.9 13.8   5 6.16 0.383 19.3, 55.0 -1.47
LPB6F1 f 44.2 20.1   3 11.6 0.456 21.5, 59.9 -0.56
LPB6F1 m 33.7 28.0   5 12.5 0.831 -15.3, 54.2 -1.69
MAB6F1 f 45.9 14.8   6 6.03 0.322 27.0, 64.0 -0.41
MAB6F1 m 58.3 7.12   5 3.18 0.122 49.9, 68.3 0.74
MRLB6F1 f 56.8 9.55   7 3.61 0.168 41.8, 67.1 0.57
MRLB6F1 m 48.5 17.9   5 8.0 0.369 31.2, 71.4 -0.23
NODB6F1 f 42.8 11.8   5 5.26 0.274 23.1, 51.6 -0.68
NODB6F1 m 46.1 33.9   6 13.8 0.735 -10.3, 80.5 -0.46
NONB6F1 f 52.6 15.0   4 7.48 0.284 33.7, 66.3 0.2
NONB6F1 m 44.0 18.5   5 8.29 0.421 13.6, 62.6 -0.67
NZBB6F1 f 39.4 11.4   5 5.09 0.289 25.7, 50.5 -0.99
NZBB6F1 m 60.8 5.49   4 2.74 0.0902 56.1, 67.4 0.98
NZWB6F1 f 27.9 8.31   4 4.15 0.298 17.2, 37.5 -2.02
NZWB6F1 m 29.1 39.4   6 16.1 1.36 -49.5, 58.4 -2.14
PLB6F1 f 41.3 8.73   5 3.9 0.211 30.5, 49.9 -0.82
PLB6F1 m 51.2 17.1   6 6.97 0.334 31.3, 70.1 0.04
RIIIB6F1 f 50.1 11.3   5 5.03 0.225 35.1, 61.2 -0.03
RIIIB6F1 m 49.1 19.3   7 7.29 0.393 16.6, 67.0 -0.17
SEAB6F1 f 43.0 18.9   9 6.3 0.44 16.0, 66.7 -0.67
SEAB6F1 m 46.2 21.7   7 8.2 0.47 21.7, 72.4 -0.45
SJLB6F1 f 45.9 17.3   6 7.06 0.377 18.3, 69.0 -0.41
SJLB6F1 m 45.0 18.8   4 9.38 0.416 24.3, 65.5 -0.57
SMB6F1 f 43.2 7.48   3 4.32 0.173 34.6, 48.2 -0.65
SMB6F1 m 40.4 16.2   6 6.63 0.403 25.0, 67.2 -1.03
SWRB6F1 f 52.4 26.3   4 13.2 0.503 13.5, 70.3 0.18
SWRB6F1 m 46.5 20.9   4 10.5 0.45 28.5, 75.8 -0.42


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129SB6F1 f 54.1 6.8902 67.6713 40.5287
129SB6F1 m 51.94 7.5478 66.8066 37.0734
AB6F1 f 57.7333 9.7442 76.926 38.5406
AB6F1 m 58.875 8.4387 75.4964 42.2536
AKB6F1 f 57.225 8.4387 73.8464 40.6036
AKB6F1 m 53.4 11.9342 76.9062 29.8938
BKSB6F1 f 57.18 7.5478 72.0466 42.3134
BKSB6F1 m 73.1833 6.8902 86.7546 59.612
BTBRB6F1 f 55.9 8.4387 72.5214 39.2786
BTBRB6F1 m 53.25 8.4387 69.8714 36.6286
BUB6F1 f 72.4143 6.3791 84.9789 59.8497
BUB6F1 m 64.34 7.5478 79.2066 49.4734
C3B6F1 f 52.5 8.4387 69.1214 35.8786
C3B6F1 m 35.1 8.4387 51.7214 18.4786
C57BL/6J f 71.35 5.9671 83.1031 59.5969
C57BL/6J m 69.0889 5.6258 80.1698 58.008
C57LB6F1 f 53.4286 6.3791 65.9931 40.864
C57LB6F1 m 52.94 7.5478 67.8066 38.0734
C58B6F1 f 46.2833 6.8902 59.8546 32.712
C58B6F1 m 51.4333 9.7442 70.626 32.2406
CBAB6F1 f 57.72 7.5478 72.5866 42.8534
CBAB6F1 m 53.35 8.4387 69.9714 36.7286
CByB6F1 f 38.05 8.4387 54.6714 21.4286
CByB6F1 m 52.15 8.4387 68.7714 35.5286
D2B6F1 f 53.68 7.5478 68.5466 38.8134
D2B6F1 m 52.64 7.5478 67.5066 37.7734
DDYB6F1 f 74.725 8.4387 91.3464 58.1036
DDYB6F1 m 64.52 7.5478 79.3866 49.6534
FVBB6F1 f 56.72 7.5478 71.5866 41.8534
FVBB6F1 m 56.1286 6.3791 68.6931 43.564
IB6F1 f 39.5333 6.8902 53.1046 25.962
IB6F1 m 47.3167 6.8902 60.888 33.7454
KKB6F1 f 28.45 8.4387 45.0714 11.8286
KKB6F1 m 35.9 7.5478 50.7666 21.0334
LPB6F1 f 44.2 9.7442 63.3927 25.0073
LPB6F1 m 33.68 7.5478 48.5466 18.8134
MAB6F1 f 45.8833 6.8902 59.4546 32.312
MAB6F1 m 58.26 7.5478 73.1266 43.3934
MRLB6F1 f 56.7857 6.3791 69.3503 44.2211
MRLB6F1 m 48.48 7.5478 63.3466 33.6134
NODB6F1 f 42.82 7.5478 57.6866 27.9534
NODB6F1 m 46.0667 6.8902 59.638 32.4954
NONB6F1 f 52.65 8.4387 69.2714 36.0286
NONB6F1 m 43.98 7.5478 58.8466 29.1134
NZBB6F1 f 39.44 7.5478 54.3066 24.5734
NZBB6F1 m 60.825 8.4387 77.4464 44.2036
NZWB6F1 f 27.85 8.4387 44.4714 11.2286
NZWB6F1 m 29.05 6.8902 42.6213 15.4787
PLB6F1 f 41.26 7.5478 56.1266 26.3934
PLB6F1 m 51.2167 6.8902 64.788 37.6454
RIIIB6F1 f 50.1 7.5478 64.9666 35.2334
RIIIB6F1 m 49.1 6.3791 61.6646 36.5354
SEAB6F1 f 42.9556 5.6258 54.0365 31.8746
SEAB6F1 m 46.1571 6.3791 58.7217 33.5926
SJLB6F1 f 45.9167 6.8902 59.488 32.3454
SJLB6F1 m 45.025 8.4387 61.6464 28.4036
SMB6F1 f 43.2 9.7442 62.3927 24.0073
SMB6F1 m 40.35 6.8902 53.9213 26.7787
SWRB6F1 f 52.4 8.4387 69.0214 35.7786
SWRB6F1 m 46.525 8.4387 63.1464 29.9036


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129SB6F1 both 53.02 5.1099 63.0847 42.9553
AB6F1 both 58.3042 6.4452 70.9989 45.6094
AKB6F1 both 55.3125 7.3082 69.707 40.918
BKSB6F1 both 65.1817 5.1099 75.2464 55.1169
BTBRB6F1 both 54.575 5.9671 66.3281 42.8219
BUB6F1 both 68.3771 4.9412 78.1096 58.6447
C3B6F1 both 43.8 5.9671 55.5531 32.0469
C57BL/6J both 70.2194 4.1005 78.296 62.1429
C57LB6F1 both 53.1843 4.9412 62.9168 43.4518
C58B6F1 both 48.8583 5.9671 60.6114 37.1053
CBAB6F1 both 55.535 5.6609 66.685 44.385
CByB6F1 both 45.1 5.9671 56.8531 33.3469
D2B6F1 both 53.16 5.3371 63.6723 42.6477
DDYB6F1 both 69.6225 5.6609 80.7725 58.4725
FVBB6F1 both 56.4243 4.9412 66.1568 46.6918
IB6F1 both 43.425 4.8721 53.0214 33.8286
KKB6F1 both 32.175 5.6609 43.325 21.025
LPB6F1 both 38.94 6.1628 51.0785 26.8015
MAB6F1 both 52.0717 5.1099 62.1364 42.0069
MRLB6F1 both 52.6329 4.9412 62.3653 42.9004
NODB6F1 both 44.4433 5.1099 54.5081 34.3786
NONB6F1 both 48.315 5.6609 59.465 37.165
NZBB6F1 both 50.1325 5.6609 61.2825 38.9825
NZWB6F1 both 28.45 5.4472 39.179 17.721
PLB6F1 both 46.2383 5.1099 56.3031 36.1736
RIIIB6F1 both 49.6 4.9412 59.3325 39.8675
SEAB6F1 both 44.5563 4.2527 52.9327 36.18
SJLB6F1 both 45.4708 5.4472 56.1999 34.7418
SMB6F1 both 41.775 5.9671 53.5281 30.0219
SWRB6F1 both 49.4625 5.9671 61.2156 37.7094




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA