Project measure / variable:   Schughart3   pctbwB_d7

ID, description, units MPD:57137   pctbwB_d7   body weight as percent of baseline, 2000 FFU group   [%]  post-infection day 7  
influenza A (H3N2) virus study
Data set, strains Schughart3   inbred w/CC8   5 strains     sex: both     age: 7-13wks
Procedure body weight
Ontology mappings

  STRAIN COMPARISON PLOT
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Schughart3 - body weight as percent of baseline, 2000 FFU group post-infection day 7



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested4 strains5 strains
Mean of the strain means83.5   % 81.0   %
Median of the strain means83.8   % 75.0   %
SD of the strain means± 12.1 ± 11.5
Coefficient of variation (CV)0.145 0.142
Min–max range of strain means72.1   –   94.4   % 71.5   –   94.6   %
Mean sample size per strain6.5   mice 5.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 25.1757 25.1757 1.3936 0.2439
strain 3 4352.5022 1450.8341 80.3134 < 0.0001
sex:strain 3 27.0862 9.0287 0.4998 0.6843
Residuals 46 830.9739 18.0646


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 74.1 5.52   2   3.9 0.0745 70.2, 78.0 -0.78
129S1/SvImJ m 75.0 4.51   5 2.02 0.0602 70.6, 80.3 -0.52
C57BL/6J m 71.6 0.0   1   0.0 0.0 71.6, 71.6 -0.82
NOD/ShiLtJ f 72.1 1.34   4 0.669 0.0186 70.8, 73.3 -0.95
NOD/ShiLtJ m 71.5 1.12   3 0.646 0.0156 70.2, 72.3 -0.83
NZO/HlLtJ f 93.6 3.55   9 1.18 0.0379 85.9, 97.8 0.83
NZO/HlLtJ m 94.6 2.22   10 0.701 0.0234 91.9, 97.3 1.18
PWK/PhJ f 94.4 6.29   11 1.9 0.0666 85.2, 102.0 0.9
PWK/PhJ m 92.3 4.36   10 1.38 0.0472 87.4, 98.8 0.98


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 74.105 3.0054 80.1545 68.0555
129S1/SvImJ m 75.01 1.9008 78.8361 71.1839
NOD/ShiLtJ f 72.125 2.1251 76.4027 67.8473
NOD/ShiLtJ m 71.5233 2.4539 76.4627 66.5839
NZO/HlLtJ f 93.6478 1.4168 96.4995 90.796
NZO/HlLtJ m 94.597 1.344 97.3024 91.8916
PWK/PhJ f 94.4473 1.2815 97.0268 91.8677
PWK/PhJ m 92.295 1.344 95.0004 89.5896


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 74.5575 1.778 78.1364 70.9786
NOD/ShiLtJ both 71.8242 1.6231 75.0913 68.5571
NZO/HlLtJ both 94.1224 0.9764 96.0878 92.1569
PWK/PhJ both 93.3711 0.9285 95.2402 91.5021




  GWAS USING LINEAR MIXED MODELS