Project measure / variable:   Schughart3   pctbwA_d5

ID, description, units MPD:57115   pctbwA_d5   body weight as percent of baseline, 10 FFU group   [%]  post-infection day 5  
influenza A (H3N2) virus study
Data set, strains Schughart3   inbred w/CC8   8 strains     sex: both     age: 7-13wks
Procedure body weight
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  STRAIN COMPARISON PLOT
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Schughart3 - body weight as percent of baseline, 10 FFU group post-infection day 5



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested8 strains8 strains
Mean of the strain means86.4   % 90.3   %
Median of the strain means86.8   % 93.0   %
SD of the strain means± 6.90 ± 6.70
Coefficient of variation (CV)0.0798 0.0742
Min–max range of strain means76.9   –   96.3   % 80.3   –   97.8   %
Mean sample size per strain10.5   mice 10.2   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 832.4877 832.4877 30.5037 < 0.0001
strain 7 6307.3176 901.0454 33.0157 < 0.0001
sex:strain 7 237.7889 33.9698 1.2447 0.282
Residuals 150 4093.7081 27.2914


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 87.5 6.13   9 2.04 0.0701 78.8, 97.2 0.16
129S1/SvImJ m 95.4 4.84   11 1.46 0.0507 87.4, 104.0 0.76
A/J f 76.9 3.02   10 0.955 0.0393 71.0, 80.8 -1.38
A/J m 80.3 2.71   10 0.856 0.0337 76.8, 86.0 -1.49
C57BL/6J f 86.2 7.59   11 2.29 0.0881 75.5, 96.0 -0.03
C57BL/6J m 92.6 7.93   10 2.51 0.0857 80.2, 101.0 0.34
CAST/EiJ f 80.2 4.43   10 1.4 0.0552 73.6, 89.5 -0.9
CAST/EiJ m 82.6 4.87   7 1.84 0.059 76.6, 89.6 -1.15
NOD/ShiLtJ f 90.6 7.06   10 2.23 0.0779 79.1, 103.0 0.61
NOD/ShiLtJ m 95.5 5.07   15 1.31 0.0532 85.5, 104.0 0.77
NZO/HlLtJ f 96.3 4.02   10 1.27 0.0418 87.8, 103.0 1.43
NZO/HlLtJ m 97.8 4.32   9 1.44 0.0442 92.7, 104.0 1.12
PWK/PhJ f 93.4 3.06   12 0.882 0.0327 88.8, 98.1 1.01
PWK/PhJ m 93.5 6.2   10 1.96 0.0663 86.2, 108.0 0.48
WSB/EiJ f 80.2 3.47   12 1.0 0.0432 74.2, 85.0 -0.9
WSB/EiJ m 84.8 5.42   10 1.71 0.0639 78.9, 92.8 -0.82


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 87.5111 1.7414 90.9519 84.0703
129S1/SvImJ m 95.44 1.5751 98.5523 92.3277
A/J f 76.861 1.652 80.1252 73.5968
A/J m 80.33 1.652 83.5942 77.0658
C57BL/6J f 86.15 1.5751 89.2623 83.0377
C57BL/6J m 92.565 1.652 95.8292 89.3008
CAST/EiJ f 80.186 1.652 83.4502 76.9218
CAST/EiJ m 82.5871 1.9745 86.4886 78.6857
NOD/ShiLtJ f 90.556 1.652 93.8202 87.2918
NOD/ShiLtJ m 95.4727 1.3489 98.1379 92.8074
NZO/HlLtJ f 96.282 1.652 99.5462 93.0178
NZO/HlLtJ m 97.7789 1.7414 101.2197 94.3381
PWK/PhJ f 93.4158 1.5081 96.3956 90.436
PWK/PhJ m 93.528 1.652 96.7922 90.2638
WSB/EiJ f 80.2125 1.5081 83.1923 77.2327
WSB/EiJ m 84.785 1.652 88.0492 81.5208


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 91.4756 1.174 93.7953 89.1558
A/J both 78.5955 1.1681 80.9036 76.2874
C57BL/6J both 89.3575 1.1413 91.6126 87.1024
CAST/EiJ both 81.3866 1.2872 83.93 78.8431
NOD/ShiLtJ both 93.0143 1.0664 95.1214 90.9073
NZO/HlLtJ both 97.0304 1.2002 99.4018 94.659
PWK/PhJ both 93.4719 1.1184 95.6818 91.262
WSB/EiJ both 82.4987 1.1184 84.7086 80.2889




  GWAS USING LINEAR MIXED MODELS